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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:elemental iodine
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Accession:CHEBI:36893 term browser browse the term


show annotations for term's descendants           Sort by:
1,1-dimethyl-4-phenylpiperazinium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO
EXP		 Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding competes with [Epibatidine binds to Chrna2 protein]		 CTD
RGD		 PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO
EXP		 Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding [Epibatidine binds to Chrna3 protein]		 CTD
RGD		 PMID:9454827 PMID:15016836 RGD:2303194 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO
EXP		 Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrna4 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrna4 protein]		 CTD
RGD		 PMID:9454827 PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions
increases response to substance
increases activity		 ISO Dimethylphenylpiperazinium Iodide inhibits the reaction [Bungarotoxins binds to CHRNA7 protein]
CHRNA7 protein mutant form results in increased susceptibility to Dimethylphenylpiperazinium Iodide
Dimethylphenylpiperazinium Iodide results in increased activity of CHRNA7 protein		 CTD PMID:10082212 PMID:10216184 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP		 Dimethylphenylpiperazinium Iodide inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]
1,1-dimethyl-4-phenylpiperazinium iodide affects binding to Chrnb2 protein; 1,1-dimethyl-4-phenylpiperazinium iodide competes with [Epibatidine binds to Chrnb2 protein]		 CTD
RGD		 PMID:14645658 PMID:15016836 RGD:2303194 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]; Dimethylphenylpiperazinium Iodide results in increased activity of [CHRNB4 protein binds to CHRNA4 protein] CTD PMID:9454827 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Tnf tumor necrosis factor increases activity EXP TNF results in increased activity of Dimethylphenylpiperazinium Iodide CTD PMID:15086448 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
4-DAMP methiodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 affects binding IDA 4-DAMP methiodide inhibits response to acetylcholine in rat aortic rings RGD PMID:8075871 RGD:2303390 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
diiodine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca4 ATP binding cassette subfamily A member 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ABCA4 mRNA CTD PMID:36706583 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ABCC6 mRNA CTD PMID:36706583 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ACOX2 mRNA CTD PMID:36706583 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ACTA2 mRNA CTD PMID:36706583 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of ADAMTS19 mRNA CTD PMID:36706583 NCBI chr18:52,346,448...52,531,245
Ensembl chr18:52,347,428...52,530,509 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ADRB3 mRNA CTD PMID:36706583 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ALDH1A1 mRNA CTD PMID:36706583 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH1L1 protein CTD PMID:30090431 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of ALDH5A1 protein CTD PMID:30090431 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Angptl2 angiopoietin-like 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ANGPTL2 mRNA CTD PMID:36706583 NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178 		JBrowse link
G Anxa8 annexin A8 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of ANXA8 mRNA CTD PMID:36706583 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of APOBEC1 mRNA CTD PMID:36706583 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390 		JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of AQP1 mRNA CTD PMID:36706583 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Art3 ADP-ribosyltransferase 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ART3 mRNA CTD PMID:36706583 NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BAX protein CTD PMID:17173243 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased expression of BCL2 protein CTD PMID:17173243 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G C1qtnf2 C1q and TNF related 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of C1QTNF2 mRNA CTD PMID:36706583 NCBI chr10:27,941,948...27,958,926
Ensembl chr10:27,941,948...27,959,185 		JBrowse link
G Calml4 calmodulin-like 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CALML4 mRNA CTD PMID:36706583 NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Diatrizoate co-treated with Iodine] results in increased activity of CASP3 protein CTD PMID:17173243 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cbr2 carbonyl reductase 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CBR2 mRNA CTD PMID:36706583 NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001 		JBrowse link
G Cck cholecystokinin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CCK mRNA CTD PMID:36706583 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ccl28 C-C motif chemokine ligand 28 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CCL28 mRNA CTD PMID:36706583 NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CCL3 mRNA CTD PMID:36706583 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CCN2 mRNA CTD PMID:36706583 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cd274 CD274 molecule increases expression
multiple interactions		 ISO Iodine results in increased expression of CD274 mRNA
CD274 protein affects the reaction [Iodine results in increased expression of PDCD1 mRNA]; CD274 protein affects the reaction [Iodine results in increased expression of PDCD1 protein]; CD274 protein affects the reaction [Iodine results in increased expression of PDCD1LG2 mRNA]		 CTD PMID:37598415 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd79a CD79a molecule multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CD79A mRNA CTD PMID:36706583 NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935 		JBrowse link
G Cd86 CD86 molecule increases expression EXP Iodine results in increased expression of CD86 mRNA CTD PMID:19035182 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdh23 cadherin-related 23 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CDH23 mRNA CTD PMID:36706583 NCBI chr20:28,240,643...28,622,490
Ensembl chr20:28,240,645...28,622,419 		JBrowse link
G Cdh3 cadherin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CDH3 mRNA CTD PMID:36706583 NCBI chr19:34,393,596...34,444,084
Ensembl chr19:34,393,727...34,444,084 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 decreases expression EXP Iodine deficiency results in decreased expression of CDK5R1 protein CTD PMID:22987596 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CEACAM10 mRNA CTD PMID:36706583 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915 		JBrowse link
G Cibar2 CBY1 interacting BAR domain containing 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FAM92B mRNA CTD PMID:36706583 NCBI chr19:48,217,617...48,229,418
Ensembl chr19:48,215,486...48,229,404 		JBrowse link
G Cimip2c ciliary microtubule inner protein 2C multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FAM166C mRNA CTD PMID:36706583 NCBI chr 6:25,905,294...25,923,615
Ensembl chr 6:25,905,294...25,923,615 		JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases abundance
increases uptake		 ISO CLCN5 gene mutant form results in increased abundance of Iodine
CLCN5 gene mutant form results in increased uptake of Iodine		 CTD PMID:16306076 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264 		JBrowse link
G Cldn2 claudin 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CLDN2 mRNA CTD PMID:36706583 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cldn5 claudin 5 multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of CLDN5 protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; Iodine results in increased expression of and results in increased localization of CLDN5 protein CTD PMID:16514648 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Clec7a C-type lectin domain containing 7A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CLEC7A mRNA CTD PMID:36706583 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Iodine results in increased expression of COL1A1 mRNA CTD PMID:22083529 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col24a1 collagen type XXIV alpha 1 chain multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of COL24A1 mRNA CTD PMID:36706583 NCBI chr 2:234,212,256...234,469,445
Ensembl chr 2:234,212,324...234,469,441 		JBrowse link
G Col4a3 collagen type IV alpha 3 chain multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of COL4A3 mRNA CTD PMID:36706583 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of COL8A1 mRNA CTD PMID:36706583 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of COLQ mRNA CTD PMID:36706583 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107 		JBrowse link
G Cort cortistatin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CORT mRNA CTD PMID:36706583 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cplx3 complexin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CPLX3 mRNA CTD PMID:36706583 NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297 		JBrowse link
G Cpz carboxypeptidase Z multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CPZ mRNA CTD PMID:36706583 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of CRHR2 mRNA CTD PMID:36706583 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Crygn crystallin, gamma N multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CRYGN mRNA CTD PMID:36706583 NCBI chr 4:10,394,015...10,401,542
Ensembl chr 4:10,394,020...10,401,543 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of CTH protein CTD PMID:30090431 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cwh43 cell wall biogenesis 43 C-terminal homolog multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CWH43 mRNA CTD PMID:36706583 NCBI chr14:34,754,279...34,800,530
Ensembl chr14:34,754,289...34,800,814 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of CYB5A protein CTD PMID:30090431 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CYP11A1 mRNA CTD PMID:36706583 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CYP19A1 mRNA CTD PMID:36706583 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Iodine deficiency co-treated with Propylthiouracil] results in increased expression of CYP2B10 mRNA CTD PMID:22503787 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CYP2F2 mRNA CTD PMID:36706583 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Depp1 DEPP autophagy regulator 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DEPP1 mRNA CTD PMID:36706583 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity
multiple interactions
increases expression
decreases expression		 ISO
EXP		 Iodine results in decreased activity of DIO1 protein
Methylnitrosourea inhibits the reaction [Iodine results in increased expression of DIO1 mRNA]
Selenium inhibits the reaction [Iodine results in decreased activity of DIO1 protein]; Selenium inhibits the reaction [Iodine results in decreased expression of DIO1 mRNA]		 CTD PMID:15922087 PMID:17044649 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DIO3 mRNA CTD PMID:36706583 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dio3os DIO3 opposite strand upstream RNA multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DIO3OS mRNA CTD PMID:36706583
G Dmbt1l1 deleted in malignant brain tumors 1 like 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CDCP3 mRNA CTD PMID:36706583 NCBI chr 1:185,949,897...186,084,340
Ensembl chr 1:185,949,881...186,084,338 		JBrowse link
G Dmkn dermokine multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DMKN mRNA CTD PMID:36706583 NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006 		JBrowse link
G Dmrt2 doublesex and mab-3 related transcription factor 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DMRT2 mRNA CTD PMID:36706583 NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DRD3 mRNA CTD PMID:36706583 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Dsc3 desmocollin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DSC3 mRNA CTD PMID:36706583 NCBI chr18:11,379,759...11,413,797
Ensembl chr18:11,377,347...11,413,797 		JBrowse link
G Dthd1 death domain containing 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of DTHD1 mRNA CTD PMID:36706583 NCBI chr14:46,670,438...46,673,183 JBrowse link
G Edaradd EDAR associated via death domain multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of EDARADD mRNA CTD PMID:36706583 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G Edn3 endothelin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of EDN3 mRNA CTD PMID:36706583 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Emx1 empty spiracles homeobox 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of EMX1 mRNA CTD PMID:36706583 NCBI chr 4:117,725,148...117,741,616
Ensembl chr 4:117,725,155...117,741,613 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ENPP2 mRNA CTD PMID:36706583 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Epn3 epsin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of EPN3 mRNA CTD PMID:36706583 NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356 		JBrowse link
G F5 coagulation factor V multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of F5 mRNA CTD PMID:36706583 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FAM180A mRNA CTD PMID:36706583 NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047 		JBrowse link
G Fap fibroblast activation protein, alpha multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FAP mRNA CTD PMID:36706583 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545 		JBrowse link
G Fat2 FAT atypical cadherin 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FAT2 mRNA CTD PMID:36706583 NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216 		JBrowse link
G Fbn2 fibrillin 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of FBN2 mRNA CTD PMID:36706583 NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976 		JBrowse link
G Fbxl22 F-box and leucine-rich repeat protein 22 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FBXL22 mRNA CTD PMID:36706583 NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685 		JBrowse link
G Fezf2 Fez family zinc finger 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FEZF2 mRNA CTD PMID:36706583 NCBI chr15:12,768,614...12,777,554
Ensembl chr15:12,773,762...12,777,554 		JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FGF7 mRNA CTD PMID:36706583 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Folr1 folate receptor alpha multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of FOLR1 mRNA CTD PMID:36706583 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Iodine results in increased expression of FOS mRNA; Iodine results in increased expression of FOS protein
[Selenium co-treated with Iodine] results in increased expression of FOS mRNA; [Selenium co-treated with Iodine] results in increased expression of FOS protein		 CTD PMID:12475444 PMID:12666833 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Frmd7 FERM domain containing 7 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of FRMD7 mRNA CTD PMID:36706583 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in decreased expression of FTCD protein CTD PMID:30090431 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of GAMT protein CTD PMID:30090431 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gbp4 guanylate binding protein 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GBP3 mRNA CTD PMID:36706583 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879 		JBrowse link
G Gjb6 gap junction protein, beta 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GJB6 mRNA CTD PMID:36706583 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Gkn3 gastrokine 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GKN3 mRNA CTD PMID:36706583 NCBI chr 4:119,828,859...119,833,924
Ensembl chr 4:119,829,005...119,834,842 		JBrowse link
G Gli1 GLI family zinc finger 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GLI1 mRNA CTD PMID:36706583 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gls2 glutaminase 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GLS2 mRNA CTD PMID:36706583 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Gypa glycophorin A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of GYPA mRNA CTD PMID:36706583 NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822 		JBrowse link
G Hdc histidine decarboxylase multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HDC mRNA CTD PMID:36706583 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hhatl hedgehog acyltransferase-like multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HHATL mRNA CTD PMID:36706583 NCBI chr 8:121,447,001...121,454,070
Ensembl chr 8:121,447,002...121,454,001 		JBrowse link
G Hkdc1 hexokinase domain containing 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HKDC1 mRNA CTD PMID:36706583 NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of HSD11B1 mRNA CTD PMID:36706583 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of IBSP mRNA CTD PMID:36706583 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression		 EXP
ISO		 [Iodine co-treated with Dibutyl Phthalate] results in increased expression of IFNG protein; pyrazolanthrone inhibits the reaction [[Iodine co-treated with Dibutyl Phthalate] results in increased expression of IFNG protein]
Iodine results in increased expression of IFNG protein		 CTD PMID:29385629 PMID:37598415 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of IGFBP6 mRNA CTD PMID:36706583 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression		 EXP
ISO		 [Iodine co-treated with Dibutyl Phthalate] results in increased expression of IL17A protein; pyrazolanthrone inhibits the reaction [[Iodine co-treated with Dibutyl Phthalate] results in increased expression of IL17A protein]
Iodine results in increased expression of IL17A protein		 CTD PMID:29385629 PMID:37598415 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Iodine co-treated with Dibutyl Phthalate] results in increased expression of IL1B protein CTD PMID:29385629 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 increases expression EXP
ISO		 Iodine results in increased expression of IL2 protein CTD PMID:19035182 PMID:37598415 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Iodine co-treated with Dibutyl Phthalate] results in increased expression of IL6 protein; pyrazolanthrone inhibits the reaction [[Iodine co-treated with Dibutyl Phthalate] results in increased expression of IL6 protein] CTD PMID:29385629 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Impg1 interphotoreceptor matrix proteoglycan 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of IMPG1 mRNA CTD PMID:36706583 NCBI chr 8:81,243,624...81,389,722
Ensembl chr 8:81,243,624...81,389,722 		JBrowse link
G Irx5 iroquois homeobox 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of IRX5 mRNA CTD PMID:36706583 NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ISG20 mRNA CTD PMID:36706583 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ITIH3 mRNA CTD PMID:36706583 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Iodine results in increased expression of JUN mRNA; Iodine results in increased expression of JUN protein
[Iodine co-treated with Dibutyl Phthalate] results in increased phosphorylation of and results in increased activity of JUN protein; [Selenium co-treated with Iodine] results in increased expression of JUN mRNA; [Selenium co-treated with Iodine] results in increased expression of JUN protein		 CTD PMID:12475444 PMID:12666833 PMID:29385629 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of KCNE2 mRNA CTD PMID:36706583 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of KCNJ10 mRNA CTD PMID:36706583 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of KCNJ13 mRNA CTD PMID:36706583 NCBI chr 9:88,063,003...88,071,112
Ensembl chr 9:88,063,003...88,071,112 		JBrowse link
G Kl Klotho multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of KL mRNA CTD PMID:36706583 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Klhl1 kelch-like family member 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of KLHL1 mRNA CTD PMID:36706583 NCBI chr15:72,698,191...73,142,726
Ensembl chr15:72,699,094...73,142,594 		JBrowse link
G Krt18 keratin 18 multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of KRT18 protein CTD PMID:30090431 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166 		JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of LBP mRNA CTD PMID:36706583 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lemd1 LEM domain containing 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of LEMD1 mRNA CTD PMID:36706583 NCBI chr13:43,631,705...43,697,765
Ensembl chr13:43,665,926...43,697,948 		JBrowse link
G Lep leptin multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of LEP protein CTD PMID:30090431 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of LGR5 mRNA CTD PMID:36706583 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP [Iodine deficiency co-treated with sodium perchlorate] results in decreased secretion of LHB protein CTD PMID:30090431 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Loxl1 lysyl oxidase-like 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of LOXL1 mRNA CTD PMID:36706583 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
G Lrp1 LDL receptor related protein 1 multiple interactions ISO [Iodine deficiency co-treated with Propylthiouracil] results in decreased expression of LRP1 protein; Triiodothyronine inhibits the reaction [[Iodine deficiency co-treated with Propylthiouracil] results in decreased expression of LRP1 protein] CTD PMID:23517243 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrp2 LDL receptor related protein 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of LRP2 mRNA CTD PMID:36706583 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Ly6a lymphocyte antigen 6 family member A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of LY6A mRNA CTD PMID:36706583 NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981 		JBrowse link
G Map1b microtubule-associated protein 1B decreases expression EXP Iodine deficiency results in decreased expression of MAP1B protein CTD PMID:27444543 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Mbp myelin basic protein decreases expression
multiple interactions		 ISO Iodine results in decreased expression of MBP mRNA
Selenium inhibits the reaction [Iodine results in decreased expression of MBP mRNA]		 CTD PMID:16229266 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mc3r melanocortin 3 receptor multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of MC3R mRNA CTD PMID:36706583 NCBI chr 3:161,016,347...161,017,444
Ensembl chr 3:161,016,347...161,017,444 		JBrowse link
G Mfap4 microfibril associated protein 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MFAP4 mRNA CTD PMID:36706583 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155 		JBrowse link
G Mfrp membrane frizzled-related protein multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MFRP mRNA CTD PMID:36706583 NCBI chr 8:44,445,636...44,450,859
Ensembl chr 8:44,445,697...44,450,859 		JBrowse link
G Mgp matrix Gla protein multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MGP mRNA CTD PMID:36706583 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Mirlet7bhg Mirlet7b host gene multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of LNCPPARA mRNA CTD PMID:36706583
G Misp3 MISP family member 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MISP3 mRNA CTD PMID:36706583 NCBI chr19:24,139,998...24,142,006
Ensembl chr19:24,140,033...24,142,631 		JBrowse link
G Msx1 msh homeobox 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MSX1 mRNA CTD PMID:36706583 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Mybpc3 myosin binding protein C3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MYBPC3 mRNA CTD PMID:36706583 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405 		JBrowse link
G Myh3 myosin heavy chain 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MYH3 mRNA CTD PMID:36706583 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992 		JBrowse link
G Myl4 myosin, light chain 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of MYL4 mRNA CTD PMID:36706583 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myot myotilin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of MYOT mRNA CTD PMID:36706583 NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841 		JBrowse link
G Ndnf neuron-derived neurotrophic factor multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NDNF mRNA CTD PMID:36706583 NCBI chr 4:94,944,392...94,981,871
Ensembl chr 4:94,944,360...94,981,873 		JBrowse link
G Neurod1 neuronal differentiation 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NEUROD1 mRNA CTD PMID:36706583 NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Neurod2 neuronal differentiation 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NEUROD2 mRNA CTD PMID:36706583 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986 		JBrowse link
G Neurod6 neuronal differentiation 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NEUROD6 mRNA CTD PMID:36706583 NCBI chr 4:84,846,659...84,849,905
Ensembl chr 4:84,846,231...84,849,999 		JBrowse link
G Neurog2 neurogenin 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NEUROG2 mRNA CTD PMID:36706583 NCBI chr 2:216,092,709...216,095,276
Ensembl chr 2:216,093,363...216,094,154 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Iodine deficiency results in increased expression of and results in decreased phosphorylation of NFKBIA protein CTD PMID:27444543 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nppc natriuretic peptide C multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NPPC mRNA CTD PMID:36706583 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Nptx1 neuronal pentraxin 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NPTX1 mRNA CTD PMID:36706583 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the reaction [[Iodine deficiency co-treated with Propylthiouracil] results in decreased expression of CYP3A11 mRNA] CTD PMID:22503787 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NR4A3 mRNA CTD PMID:36706583 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nrgn neurogranin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NRGN mRNA CTD PMID:36706583 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516 		JBrowse link
G Nup62cl nucleoporin 62 C-terminal like multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NUP62CL mRNA CTD PMID:36706583 NCBI chr  X:103,668,458...103,724,957
Ensembl chr  X:103,668,455...103,724,081 		JBrowse link
G Nxph3 neurexophilin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of NXPH3 mRNA CTD PMID:36706583 NCBI chr10:80,456,283...80,459,949
Ensembl chr10:80,455,429...80,462,415 		JBrowse link
G Ocln occludin multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of OCLN protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of OCLN protein; [Selenium co-treated with Iodine] results in increased expression of and results in increased localization of OCLN protein; Iodine results in increased expression of and results in increased localization of OCLN protein CTD PMID:16514648 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Optc opticin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of OPTC mRNA CTD PMID:36706583 NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237 		JBrowse link
G Otogl otogelin-like multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of OTOGL mRNA CTD PMID:36706583 NCBI chr 7:43,065,800...43,211,400
Ensembl chr 7:43,067,644...43,223,592 		JBrowse link
G Padi6 peptidyl arginine deiminase 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PADI6 mRNA CTD PMID:36706583 NCBI chr 5:153,021,855...153,037,443
Ensembl chr 5:153,021,965...153,037,414 		JBrowse link
G Paqr5 progestin and adipoQ receptor family member 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PAQR5 mRNA CTD PMID:36706583 NCBI chr 8:62,431,867...62,513,688
Ensembl chr 8:62,431,867...62,513,688 		JBrowse link
G Paqr6 progestin and adipoQ receptor family member 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PAQR6 mRNA CTD PMID:36706583 NCBI chr 2:173,832,241...173,838,443
Ensembl chr 2:173,833,880...173,838,456 		JBrowse link
G Pcdhb1 protocadherin beta 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of PCDHB1 mRNA CTD PMID:36706583 NCBI chr18:28,913,835...28,916,746
Ensembl chr18:28,913,989...28,916,445 		JBrowse link
G Pdcd1 programmed cell death 1 increases expression
multiple interactions		 ISO Iodine results in increased expression of PDCD1 mRNA; Iodine results in increased expression of PDCD1 protein
CD274 protein affects the reaction [Iodine results in increased expression of PDCD1 mRNA]; CD274 protein affects the reaction [Iodine results in increased expression of PDCD1 protein]		 CTD PMID:37598415 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 multiple interactions
increases expression		 ISO CD274 protein affects the reaction [Iodine results in increased expression of PDCD1LG2 mRNA] CTD PMID:37598415 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Pla2g5 phospholipase A2, group V multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PLA2G5 mRNA CTD PMID:36706583 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Plcxd3 phosphatidylinositol-specific phospholipase C, X domain containing 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of PLCXD3 mRNA CTD PMID:36706583 NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON1 protein; [Iodine deficiency co-treated with sodium perchlorate] results in decreased expression of PON1 protein CTD PMID:30090431 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Pon2 paraoxonase 2 multiple interactions EXP [[Iodine deficiency co-treated with sodium perchlorate] affects the susceptibility to hexabromocyclododecane] which results in increased expression of PON2 protein CTD PMID:30090431 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248 		JBrowse link
G Prdm8 PR/SET domain 8 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PRDM8 mRNA CTD PMID:36706583 NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993 		JBrowse link
G Prickle4 prickle planar cell polarity protein 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of PRICKLE4 mRNA CTD PMID:36706583 NCBI chr 9:13,297,494...13,305,635
Ensembl chr 9:13,297,758...13,305,630 		JBrowse link
G Prokr2 prokineticin receptor 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of PROKR2 mRNA CTD PMID:36706583 NCBI chr 3:119,624,738...119,639,442
Ensembl chr 3:119,627,601...119,635,718 		JBrowse link
G Prr29 proline rich 29 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PRR29 mRNA CTD PMID:36706583 NCBI chr10:91,305,820...91,320,661
Ensembl chr10:91,305,723...91,310,439 		JBrowse link
G Prr32 proline rich 32 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PRR32 mRNA CTD PMID:36706583 NCBI chr  X:123,978,010...123,979,928
Ensembl chr  X:123,977,985...123,979,942 		JBrowse link
G Prss12 serine protease 12 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of PRSS12 mRNA CTD PMID:36706583 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126 		JBrowse link
G Ptprq protein tyrosine phosphatase, receptor type, Q multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of PTPRQ mRNA CTD PMID:36706583 NCBI chr 7:42,834,455...43,016,807
Ensembl chr 7:42,837,109...43,016,917 		JBrowse link
G Rasd2 RASD family, member 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RASD2 mRNA CTD PMID:36706583 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rasl10a RAS-like, family 10, member A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RASL10A mRNA CTD PMID:36706583 NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468 		JBrowse link
G Rbp2 retinol binding protein 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RBP2 mRNA CTD PMID:36706583 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Iodine deficiency results in decreased expression of and results in decreased phosphorylation of RELA protein CTD PMID:27444543 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Robo3 roundabout guidance receptor 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of ROBO3 mRNA CTD PMID:36706583 NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315 		JBrowse link
G Rp1 RP1, axonemal microtubule associated multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RP1 mRNA CTD PMID:36706583 NCBI chr 5:15,121,104...15,582,363
Ensembl chr 5:15,121,133...15,579,363 		JBrowse link
G Rspo2 R-spondin 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RSPO2 mRNA CTD PMID:36706583 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933 		JBrowse link
G Rtn4rl2 reticulon 4 receptor-like 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of RTN4RL2 mRNA CTD PMID:36706583 NCBI chr 3:69,954,557...69,971,108
Ensembl chr 3:69,955,169...69,971,488 		JBrowse link
G Rxfp3 relaxin family peptide receptor 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of RXFP3 mRNA CTD PMID:36706583 NCBI chr 2:60,003,256...60,004,686
Ensembl chr 2:60,003,256...60,004,686 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of S100A8 mRNA CTD PMID:36706583 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of S100A9 mRNA CTD PMID:36706583 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Satb2 SATB homeobox 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SATB2 mRNA CTD PMID:36706583 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Scara5 scavenger receptor class A, member 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SCARA5 mRNA CTD PMID:36706583 NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SCD1 mRNA CTD PMID:36706583 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of SCN9A mRNA CTD PMID:36706583 NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516 		JBrowse link
G Sebox SEBOX homeobox multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SEBOX mRNA CTD PMID:36706583 NCBI chr10:63,399,215...63,400,086
Ensembl chr10:63,399,165...63,400,606 		JBrowse link
G Sec14l4 SEC14-like lipid binding 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SEC14L4 mRNA CTD PMID:36706583 NCBI chr14:78,912,750...78,928,799
Ensembl chr14:78,912,750...78,956,099 		JBrowse link
G Sema3c semaphorin 3C multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SEMA3C mRNA CTD PMID:36706583 NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SEMA7A mRNA CTD PMID:36706583 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Serpina7 serpin family A member 7 multiple interactions EXP [Iodine co-treated with Dibutyl Phthalate] results in increased expression of SERPINA7 protein; pyrazolanthrone inhibits the reaction [[Iodine co-treated with Dibutyl Phthalate] results in increased expression of SERPINA7 protein] CTD PMID:29385629 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of SFRP2 mRNA CTD PMID:36706583 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sfrp5 secreted frizzled-related protein 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SFRP5 mRNA CTD PMID:36706583 NCBI chr 1:241,006,762...241,011,224
Ensembl chr 1:241,006,762...241,011,224 		JBrowse link
G Sgpp2 sphingosine-1-phosphate phosphatase 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SGPP2 mRNA CTD PMID:36706583 NCBI chr 9:79,762,658...79,884,665
Ensembl chr 9:79,763,284...79,880,457 		JBrowse link
G Six2 SIX homeobox 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SIX2 mRNA CTD PMID:36706583 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Slc13a4 solute carrier family 13 member 4 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC13A4 mRNA CTD PMID:36706583 NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC17A7 mRNA CTD PMID:36706583 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC22A3 mRNA CTD PMID:36706583 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC22A6 mRNA CTD PMID:36706583 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173 		JBrowse link
G Slc26a10 solute carrier family 26, member 10 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC26A10 mRNA CTD PMID:36706583 NCBI chr 7:62,995,165...63,005,099
Ensembl chr 7:62,995,381...63,004,087 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC26A3 mRNA CTD PMID:36706583 NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 increases expression
multiple interactions		 EXP Iodine results in increased expression of SLC26A4 mRNA
Methylnitrosourea promotes the reaction [Iodine results in increased expression of SLC26A4 mRNA]		 CTD PMID:15922087 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc27a6 solute carrier family 27 member 6 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of SLC27A6 mRNA CTD PMID:36706583 NCBI chr18:52,040,241...52,099,622
Ensembl chr18:52,041,074...52,099,414 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC47A1 mRNA CTD PMID:36706583 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc4a5 solute carrier family 4 member 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SLC4A5 mRNA CTD PMID:36706583 NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases uptake
affects transport		 ISO
EXP		 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; 5-nitro-2-(3-phenylpropylamino)benzoic acid inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; [[Butyrates co-treated with decitabine] results in increased expression of SLC5A5 mRNA] which results in increased uptake of Iodine; captax inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; cypermethrin inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; decamethrin inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; Dibutyl Phthalate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; Indomethacin inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; mancozeb inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; polymarcine inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]; triclocarban inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine]
SLC5A5 protein affects the transport of Iodine		 CTD PMID:12602914 PMID:17332617 PMID:17408651 PMID:17967635 PMID:27979590 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SNED1 mRNA CTD PMID:36706583 NCBI chr 9:93,774,087...93,834,003
Ensembl chr 9:93,774,119...93,830,694 		JBrowse link
G Sostdc1 sclerostin domain containing 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SOSTDC1 mRNA CTD PMID:36706583 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
G Sowahb sosondowah ankyrin repeat domain family member B multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SOWAHB mRNA CTD PMID:36706583 NCBI chr14:15,029,203...15,033,038
Ensembl chr14:15,029,395...15,031,698 		JBrowse link
G Spo11 SPO11 initiator of meiotic double strand breaks multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SPO11 mRNA CTD PMID:36706583 NCBI chr 3:161,755,299...161,770,930
Ensembl chr 3:161,757,519...161,770,925 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SPTLC3 mRNA CTD PMID:36706583 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Srl sarcalumenin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of SRL mRNA CTD PMID:36706583 NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101 		JBrowse link
G Stac SH3 and cysteine rich domain multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of STAC mRNA CTD PMID:36706583 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008 		JBrowse link
G Stoml3 stomatin like 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of STOML3 mRNA CTD PMID:36706583 NCBI chr 2:137,572,691...137,582,402
Ensembl chr 2:137,572,691...137,590,681 		JBrowse link
G Strc stereocilin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of STRC mRNA CTD PMID:36706583 NCBI chr 3:108,335,920...108,355,114
Ensembl chr 3:108,335,747...108,354,134 		JBrowse link
G Tbr1 T-box brain transcription factor 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TBR1 mRNA CTD PMID:36706583 NCBI chr 3:46,350,237...46,368,397
Ensembl chr 3:46,351,213...46,361,041 		JBrowse link
G Tekt3 tektin 3 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TEKT3 mRNA CTD PMID:36706583 NCBI chr10:47,729,635...47,763,589
Ensembl chr10:47,729,635...47,763,588 		JBrowse link
G Tf transferrin multiple interactions ISO [ferric pyrophosphate co-treated with Iodine] results in increased expression of TF protein CTD PMID:16772442 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfrc transferrin receptor multiple interactions ISO [ferric pyrophosphate co-treated with Iodine] results in increased expression of TFRC protein CTD PMID:16772442 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tg thyroglobulin increases expression ISO Iodine results in increased expression of TG protein CTD PMID:37598415 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of THBS1 mRNA CTD PMID:36706583 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thra thyroid hormone receptor alpha increases expression
multiple interactions		 ISO Iodine results in increased expression of THRA mRNA
Selenium inhibits the reaction [Iodine results in increased expression of THRA mRNA]		 CTD PMID:17555094 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta increases expression
multiple interactions		 ISO Iodine results in increased expression of THRB mRNA
Selenium inhibits the reaction [Iodine results in increased expression of THRB mRNA]		 CTD PMID:17555094 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 protein; Iodine results in increased expression of and results in increased localization of TJP1 protein CTD PMID:16514648 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlr1 toll-like receptor 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of TLR1 mRNA CTD PMID:36706583 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tlr5 toll-like receptor 5 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of TLR5 mRNA CTD PMID:36706583 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tmem252 transmembrane protein 252 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TMEM252 mRNA CTD PMID:36706583 NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943 		JBrowse link
G Tmem72 transmembrane protein 72 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TMEM72 mRNA CTD PMID:36706583 NCBI chr 4:149,946,296...149,973,550
Ensembl chr 4:149,948,257...149,973,550 		JBrowse link
G Tmem82 transmembrane protein 82 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of TMEM82 mRNA CTD PMID:36706583 NCBI chr 5:153,927,486...153,931,942
Ensembl chr 5:153,927,471...153,936,979 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO Iodine inhibits the reaction [Mustard Gas results in increased expression of TNF protein]
Iodine results in increased expression of TNF protein		 CTD PMID:16001271 PMID:37598415 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TNNT1 mRNA CTD PMID:36706583 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
G Tnxb tenascin XB multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of TNXB mRNA CTD PMID:36706583
G Tp63 tumor protein p63 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TRP63 mRNA CTD PMID:36706583 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Trabd2b TraB domain containing 2B multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TRABD2B mRNA CTD PMID:36706583 NCBI chr 5:127,941,198...128,158,946
Ensembl chr 5:127,941,114...128,143,747 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TRAF1 mRNA CTD PMID:36706583 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TRAF3IP2 mRNA CTD PMID:36706583 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
increases secretion
affects abundance		 ISO
EXP		 efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]; Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]; sodium perchlorate inhibits the reaction [efavirenz promotes the reaction [TSHB protein affects the abundance of Iodine]]; sodium perchlorate inhibits the reaction [Nevirapine promotes the reaction [TSHB protein affects the abundance of Iodine]]
[Iodine deficiency co-treated with sodium perchlorate] results in increased secretion of TSHB protein
Iodine deficiency results in increased secretion of TSHB protein		 CTD PMID:16030158 PMID:20882593 PMID:30090431 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Ttr transthyretin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TTR mRNA CTD PMID:36706583 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tuba8 tubulin, alpha 8 multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of TUBA8 mRNA CTD PMID:36706583 NCBI chr 4:154,440,045...154,456,918
Ensembl chr 4:154,440,074...154,456,917 		JBrowse link
G Ucma upper zone of growth plate and cartilage matrix associated multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of UCMA mRNA CTD PMID:36706583 NCBI chr17:73,293,977...73,303,709
Ensembl chr17:73,293,978...73,303,611 		JBrowse link
G Unc5cl unc-5 family C-terminal like multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of UNC5CL mRNA CTD PMID:36706583 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233 		JBrowse link
G Ush1c USH1 protein network component harmonin multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of USH1C mRNA CTD PMID:36706583 NCBI chr 1:96,695,303...96,743,671
Ensembl chr 1:96,695,307...96,743,671 		JBrowse link
G Ush1g USH1 protein network component sans multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of USH1G mRNA CTD PMID:36706583 NCBI chr10:100,559,721...100,563,590
Ensembl chr10:100,557,629...100,563,590 		JBrowse link
G Vip vasoactive intestinal peptide multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of VIP mRNA CTD PMID:36706583 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Wnt9a Wnt family member 9A multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of WNT9A mRNA CTD PMID:36706583 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
G Yy2 YY2 transcription factor multiple interactions ISO [Propylthiouracil co-treated with Iodine deficiency] results in increased expression of YY2 mRNA CTD PMID:36706583 NCBI chr  X:37,438,425...37,442,047
Ensembl chr  X:37,410,811...37,464,430 		JBrowse link
ecothiopate iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Echothiophate Iodide results in decreased activity of ACHE protein CTD PMID:16978018 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Alb albumin affects binding ISO Echothiophate Iodide binds to ALB protein CTD PMID:15525694 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Bche butyrylcholinesterase decreases activity
multiple interactions		 ISO Echothiophate Iodide results in decreased activity of BCHE protein
Echothiophate Iodide inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]		 CTD PMID:7377577 PMID:16213467 PMID:17698511 PMID:21802514 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 decreases activity ISO Echothiophate Iodide results in decreased activity of NCEH1 protein CTD PMID:16978018 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
iodide salt term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase increases expression EXP Iodides deficiency results in increased expression of AASS protein CTD PMID:26795019 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
G Actb actin, beta decreases expression EXP Iodides deficiency results in decreased expression of ACTB protein CTD PMID:26795019 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 increases expression EXP Iodides deficiency results in increased expression of AGXT2 protein CTD PMID:26795019 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 increases expression EXP Iodides deficiency results in increased expression of AKR1D1 protein CTD PMID:26795019 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression EXP Iodides deficiency results in increased expression of ALDH1L1 protein CTD PMID:26795019 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 multiple interactions EXP [hexabromocyclododecane co-treated with Iodides deficiency] results in decreased expression of ALDH1L2 protein CTD PMID:26795019 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP Iodides deficiency results in decreased expression of APMAP protein CTD PMID:26795019 NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341 		JBrowse link
G Aqp1 aquaporin 1 affects expression EXP Iodides deficiency affects the expression of AQP1 mRNA CTD PMID:21623536 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Arg1 arginase 1 increases expression EXP Iodides deficiency results in increased expression of ARG1 protein CTD PMID:26795019 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Best1 bestrophin 1 multiple interactions
increases transport		 ISO PAR-1-activating peptide promotes the reaction [BEST1 protein results in increased transport of Iodides] CTD PMID:19828819 NCBI chr 1:206,629,340...206,646,085
Ensembl chr 1:206,629,500...206,646,063 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions EXP [hexabromocyclododecane co-treated with Iodides deficiency] results in decreased expression of BHMT protein CTD PMID:26795019 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Car3 carbonic anhydrase 3 increases expression EXP Iodides deficiency results in increased expression of CA3 protein CTD PMID:26795019 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO 3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; 6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein] which results in increased expression of Iodides; [[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Brefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]; fenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; geldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; geldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]] CTD PMID:18230692 PMID:18297105 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 increases expression EXP Iodides deficiency results in increased expression of CPS1 protein CTD PMID:26795019 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase increases expression
multiple interactions		 EXP Iodides deficiency results in increased expression of DMGDH protein
hexabromocyclododecane inhibits the reaction [Iodides deficiency results in increased expression of DMGDH protein]		 CTD PMID:26795019 NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528 		JBrowse link
G Eno1 enolase 1 multiple interactions EXP [hexabromocyclododecane co-treated with Iodides deficiency] results in decreased expression of ENO1 protein CTD PMID:26795019 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression EXP Iodides deficiency results in decreased expression of ETFB protein CTD PMID:26795019 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase increases expression EXP Iodides deficiency results in increased expression of ETHE1 protein CTD PMID:26795019 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression EXP Iodides deficiency results in decreased expression of FDPS protein CTD PMID:26795019 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Iodides deficiency results in increased expression of GOT1 protein CTD PMID:26795019 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression EXP Iodides deficiency results in decreased expression of GSTA1 protein CTD PMID:26795019 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP Iodides deficiency results in decreased expression of GSTA2 protein CTD PMID:26795019 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression EXP Iodides deficiency results in decreased expression of GSTA3 protein CTD PMID:26795019 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression EXP Iodides deficiency results in decreased expression of GSTA4 protein CTD PMID:26795019 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP Iodides deficiency results in decreased expression of GSTP1 protein CTD PMID:26795019 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 multiple interactions ISO Iodides inhibits the reaction [Dichloroacetic Acid results in decreased activity of GSTZ1 protein] CTD PMID:24632415 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Iodides deficiency results in decreased expression of HSP90AA1 protein CTD PMID:26795019 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression EXP Iodides deficiency results in decreased expression of HSPA5 protein CTD PMID:26795019 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression EXP Iodides deficiency results in decreased expression of HSPA8 protein CTD PMID:26795019 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Iah1 isoamyl acetate hydrolyzing esterase 1 decreases expression EXP Iodides deficiency results in decreased expression of IAH1 protein CTD PMID:26795019 NCBI chr 6:40,865,530...40,872,747
Ensembl chr 6:40,865,502...40,872,978 		JBrowse link
G Lep leptin increases expression EXP Iodides deficiency results in increased expression of LEP protein CTD PMID:26795019 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nit1 nitrilase 1 increases expression EXP Iodides deficiency results in increased expression of NIT1 protein CTD PMID:26795019 NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332 		JBrowse link
G Ogdh oxoglutarate dehydrogenase increases expression EXP Iodides deficiency results in increased expression of OGDH protein CTD PMID:26795019 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Pah phenylalanine hydroxylase increases expression EXP Iodides deficiency results in increased expression of PAH protein CTD PMID:26795019 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pc pyruvate carboxylase decreases expression EXP Iodides deficiency results in decreased expression of PC protein CTD PMID:26795019 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP Iodides deficiency results in decreased expression of PDIA3 protein CTD PMID:26795019 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pon3 paraoxonase 3 decreases expression EXP Iodides deficiency results in decreased expression of PON3 protein CTD PMID:26795019 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Ppia peptidylprolyl isomerase A decreases expression EXP Iodides deficiency results in decreased expression of PPIA protein CTD PMID:26795019 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Qprt quinolinate phosphoribosyltransferase decreases expression EXP Iodides deficiency results in decreased expression of QPRT protein CTD PMID:26795019 NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486 		JBrowse link
G Sardh sarcosine dehydrogenase increases expression EXP Iodides deficiency results in increased expression of SARDH protein CTD PMID:26795019 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions EXP Iodides results in decreased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:16027156 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions EXP Iodides results in decreased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:16027156 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451 		JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions EXP Iodides results in decreased activity of [SCNN1A protein binds to SCNN1B protein binds to SCNN1G protein] CTD PMID:16027156 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects expression EXP Iodides deficiency affects the expression of SLC22A3 mRNA CTD PMID:21623536 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 affects transport ISO SLC26A4 protein affects the transport of Iodides CTD PMID:22116359 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
affects expression
increases uptake		 ISO
EXP		 Dexamethasone promotes the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]
Iodides deficiency affects the expression of SLC5A5 mRNA		 CTD PMID:15671536 PMID:15850642 PMID:15941870 PMID:16234306 PMID:21623536 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP Iodides deficiency results in increased expression of SULT1A1 protein CTD PMID:26795019 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tf transferrin decreases expression EXP Iodides deficiency results in decreased expression of TF protein CTD PMID:26795019 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tpmt thiopurine S-methyltransferase increases expression EXP Iodides deficiency results in increased expression of TPMT protein CTD PMID:26795019 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709 		JBrowse link
G Tpo thyroid peroxidase increases oxidation ISO TPO protein results in increased oxidation of Iodides CTD PMID:25595679 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
increases expression		 ISO
EXP		 [Iodides deficiency co-treated with perchlorate] results in increased expression of TSHB protein
Iodides deficiency results in increased expression of TSHB protein		 CTD PMID:18178547 PMID:20439182 PMID:26795019 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
potassium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 EXP Potassium Iodide results in increased phosphorylation of AKT1 protein
NOX4 protein affects the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]; Selenium inhibits the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]		 CTD PMID:38013145 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor decreases expression EXP Potassium Iodide results in decreased expression of AR mRNA CTD PMID:32593569 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Potassium Iodide results in increased expression of BAX protein CTD PMID:32593569 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Potassium Iodide results in decreased expression of BCL2 protein CTD PMID:32593569 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 ISO Potassium Iodide results in increased expression of BECN1 mRNA; Potassium Iodide results in increased expression of BECN1 protein
3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]		 CTD PMID:29923297 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP Potassium Iodide results in increased expression of BID protein CTD PMID:32593569 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Potassium Iodide results in decreased expression of BIRC5 protein CTD PMID:32593569 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp3 caspase 3 increases expression EXP Potassium Iodide results in increased expression of CASP3 protein CTD PMID:32593569 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases expression EXP Potassium Iodide results in increased expression of CASP9 protein CTD PMID:32593569 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Potassium Iodide results in decreased expression of CCND1 protein CTD PMID:32593569 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Potassium Iodide results in decreased expression of CDH1 protein CTD PMID:32593569 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 decreases expression EXP Potassium Iodide results in decreased expression of CDH2 protein CTD PMID:32593569 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP Potassium Iodide results in decreased expression of CDK4 protein CTD PMID:32593569 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP Potassium Iodide results in decreased expression of CLDN1 mRNA CTD PMID:32593569 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn5 claudin 5 decreases expression EXP Potassium Iodide results in decreased expression of CLDN5 mRNA CTD PMID:32593569 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression EXP Potassium Iodide results in decreased expression of CTNNB1 protein CTD PMID:32593569 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression EXP Potassium Iodide results in decreased expression of CXADR mRNA CTD PMID:32593569 NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046 		JBrowse link
G Cycs cytochrome c, somatic increases expression EXP Potassium Iodide results in increased expression of CYCS protein CTD PMID:32593569 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of DDIT3 mRNA; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of DDIT3 protein]
Potassium Iodide results in increased expression of DDIT3 mRNA		 CTD PMID:24231001 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Duox1 dual oxidase 1 multiple interactions EXP Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX1 mRNA] CTD PMID:27568464 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563 		JBrowse link
G Duox2 dual oxidase 2 multiple interactions EXP Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX2 mRNA] CTD PMID:27568464 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO [Sodium Fluoride co-treated with Potassium Iodide] results in increased expression of ERN1 mRNA; Potassium Iodide promotes the reaction [Sodium Fluoride results in increased expression of ERN1 protein] CTD PMID:24231001 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP [bisphenol A co-treated with diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of ESR1 protein; [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein CTD PMID:29050248 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F11r F11 receptor decreases expression EXP Potassium Iodide results in decreased expression of F11R protein CTD PMID:32593569 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Fn1 fibronectin 1 decreases expression EXP Potassium Iodide results in decreased expression of FN1 mRNA CTD PMID:32593569 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Foxe1 forkhead box E1 multiple interactions EXP [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 protein] CTD PMID:27568464 NCBI chr 5:60,630,027...60,632,835
Ensembl chr 5:60,630,027...60,632,835 		JBrowse link
G Fst follistatin increases expression EXP Potassium Iodide results in increased expression of FST protein CTD PMID:32593569 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions		 EXP Potassium Iodide results in decreased expression of GPX1 mRNA
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Potassium Iodide] results in increased expression of GPX1 mRNA; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of GPX1 mRNA]		 CTD PMID:38013145 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression EXP Potassium Iodide results in decreased expression of HMOX1 protein CTD PMID:32593569 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 mRNA]; Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein] CTD PMID:24231001 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP Potassium Iodide results in decreased expression of ITGB1 protein CTD PMID:32593569 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP Potassium Iodide results in decreased expression of KIT mRNA; Potassium Iodide results in decreased expression of KIT protein CTD PMID:32593569 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Marveld2 MARVEL domain containing 2 decreases expression EXP Potassium Iodide results in decreased expression of MARVELD2 protein CTD PMID:32593569 NCBI chr 2:31,742,652...31,764,150
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression EXP Potassium Iodide results in decreased expression of NFE2L2 protein CTD PMID:32593569 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions EXP [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of NKX2-1 mRNA] CTD PMID:27568464 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP NOX4 protein affects the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein] CTD PMID:38013145 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Ocln occludin decreases expression EXP Potassium Iodide results in decreased expression of OCLN mRNA CTD PMID:32593569 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions EXP Potassium Iodide inhibits the reaction [Propylthiouracil results in increased expression of and results in increased activity of ODC1 protein] CTD PMID:8882155 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression EXP Potassium Iodide results in increased expression of PARP1 protein modified form CTD PMID:32593569 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pax8 paired box 8 multiple interactions EXP Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 protein] CTD PMID:27568464 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression		 EXP [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of PCNA protein
Potassium Iodide results in decreased expression of PCNA protein		 CTD PMID:29050248 PMID:32593569 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pten phosphatase and tensin homolog decreases expression EXP Potassium Iodide results in decreased expression of PTEN mRNA CTD PMID:38013145 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression		 ISO Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 mRNA]; Potassium Iodide inhibits the reaction [arsenic trioxide results in increased expression of PTGS2 protein]; Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased expression of PTGS2 mRNA]
Potassium Iodide results in decreased expression of PTGS2 protein		 CTD PMID:18588940 PMID:19014992 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression EXP Potassium Iodide results in decreased expression of PTK2 protein; Potassium Iodide results in decreased expression of PTK2 protein modified form CTD PMID:32593569 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions
decreases expression		 EXP Selenium inhibits the reaction [Potassium Iodide results in decreased expression of PTPN1 mRNA] CTD PMID:38013145 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA] CTD PMID:27568464 PMID:38013145 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression EXP Potassium Iodide results in increased expression of SOD1 protein CTD PMID:32593569 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased expression of SOD2 protein] CTD PMID:18588940 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 ISO 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; 3-methyladenine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]
Potassium Iodide results in increased expression of SQSTM1 mRNA; Potassium Iodide results in increased expression of SQSTM1 protein		 CTD PMID:29923297 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Potassium Iodide inhibits the reaction [monomethylarsonous acid results in increased phosphorylation of SRC protein] CTD PMID:18588940 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Testin testin gene decreases expression EXP Potassium Iodide results in decreased expression of TESTIN mRNA CTD PMID:32593569 NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385 		JBrowse link
G Tg thyroglobulin multiple interactions EXP [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG protein] CTD PMID:27568464 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression		 EXP Selenium inhibits the reaction [Potassium Iodide results in increased expression of TGFB1 mRNA] CTD PMID:38013145 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP Potassium Iodide results in decreased expression of TJP1 mRNA CTD PMID:32593569 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Potassium Iodide results in increased expression of TP53 protein CTD PMID:32593569 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpo thyroid peroxidase multiple interactions EXP [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO protein] CTD PMID:27568464 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP [diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of TSHB protein; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX2 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of NKX2-1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO protein] CTD PMID:27568464 PMID:29050248 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases expression		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Potassium Iodide results in decreased expression of TXNRD1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of TXNRD1 mRNA] CTD PMID:38013145 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Potassium Iodide inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA] CTD PMID:24231001 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
sodium iodide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions EXP Sodium Iodide promotes the reaction [perchlorate results in increased activity of CASP3 protein] CTD PMID:11834455 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cftr CF transmembrane conductance regulator affects export ISO CFTR protein affects the export of Sodium Iodide CTD PMID:14502435 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Iyd iodotyrosine deiodinase decreases expression EXP Sodium Iodide results in decreased expression of IYD mRNA CTD PMID:30814441 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions
increases uptake
increases activity
increases abundance
decreases export		 ISO
EXP		 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; dysidenin inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; Ouabain inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; perchlorate inhibits the reaction [mibolerone promotes the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]]; perchlorate inhibits the reaction [SLC5A5 protein results in increased abundance of Sodium Iodide]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; perrhenate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium bromide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium chlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of perrhenate analog]; Sodium Iodide inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Pertechnetate Tc 99m]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]; sodium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide]; sodium thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Sodium Iodide analog]
Sodium Iodide results in increased activity of SLC5A5 protein
SLC5A5 protein results in decreased export of Sodium Iodide		 CTD PMID:12488351 PMID:12489024 PMID:12541134 PMID:12601449 PMID:14633711 More... NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Tpo thyroid peroxidase multiple interactions ISO Sodium Iodide inhibits the reaction [Methimazole results in decreased activity of TPO protein] CTD PMID:7626075 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19901
    chemical entity 19899
      molecular entity 19899
        elemental molecular entity 17195
          elemental halogen 9706
            elemental iodine 343
              diatomic iodine + 240
              monoatomic iodine + 119
paths to the root