CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: apo carotenoid triterpenoid
Accession: CHEBI:36783
browse the term
Definition: A triterpenoid compound arising from loss of part of the carotene skeleton.
Synonyms: related_synonym: apocarotenoid triterpenoid; apocarotenoid triterpenoids
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Acadm
acyl-CoA dehydrogenase medium chain
increases expression
ISO
apocarotenal results in increased expression of ACADM mRNA
CTD
PMID:17034753
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Adh5
alcohol dehydrogenase 5 (class III), chi polypeptide
increases expression
ISO
apocarotenal results in increased expression of ADH5 mRNA
CTD
PMID:17034753
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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Aldh1b1
aldehyde dehydrogenase 1 family, member B1
decreases expression
ISO
apocarotenal results in decreased expression of ALDH1B1 mRNA
CTD
PMID:17034753
NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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Aldh3b1
aldehyde dehydrogenase 3 family, member B1
decreases expression
ISO
apocarotenal results in decreased expression of ALDH3B1 mRNA
CTD
PMID:17034753
NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
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Aldh4a1
aldehyde dehydrogenase 4 family, member A1
decreases expression
ISO
apocarotenal results in decreased expression of ALDH4A1 mRNA
CTD
PMID:17034753
NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345
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Ank2
ankyrin 2
increases expression
ISO
apocarotenal results in increased expression of ANK2 mRNA
CTD
PMID:17034753
NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
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Ank3
ankyrin 3
increases expression
ISO
apocarotenal results in increased expression of ANK3 mRNA
CTD
PMID:17034753
NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
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Asah1
N-acylsphingosine amidohydrolase 1
increases expression
ISO
apocarotenal results in increased expression of ASAH1 mRNA
CTD
PMID:17034753
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
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Asb1
ankyrin repeat and SOCS box-containing 1
increases expression
ISO
apocarotenal results in increased expression of ASB1 mRNA
CTD
PMID:17034753
NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
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Asb9
ankyrin repeat and SOCS box-containing 9
increases expression
ISO
apocarotenal results in increased expression of ASB9 mRNA
CTD
PMID:17034753
NCBI chr X:29,956,576...30,001,436
Ensembl chr X:29,956,576...30,001,105
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Bax
BCL2 associated X, apoptosis regulator
decreases expression
ISO
apocarotenal results in decreased expression of BAX mRNA
CTD
PMID:17034753
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bco2
beta-carotene oxygenase 2
multiple interactions
ISO
[BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Cryptoxanthins] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite; [BCO2 protein results in increased metabolism of Zeaxanthins] which results in increased chemical synthesis of apocarotenal metabolite
CTD
PMID:21106934
NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
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Casp8ap2
caspase 8 associated protein 2
increases expression
ISO
apocarotenal results in increased expression of CASP8AP2 mRNA
CTD
PMID:17034753
NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
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Cdh1
cadherin 1
increases expression
ISO
apocarotenal results in increased expression of CDH1 mRNA
CTD
PMID:17034753
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cldn10
claudin 10
increases expression
ISO
apocarotenal results in increased expression of CLDN10 mRNA
CTD
PMID:17034753
NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526
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Cldn18
claudin 18
increases expression
ISO
apocarotenal results in increased expression of CLDN18 mRNA
CTD
PMID:17034753
NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
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Col1a1
collagen type I alpha 1 chain
decreases expression
ISO
apocarotenal results in decreased expression of COL1A1 mRNA
CTD
PMID:17034753
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col4a1
collagen type IV alpha 1 chain
decreases expression
ISO
apocarotenal results in decreased expression of COL4A1 mRNA
CTD
PMID:17034753
NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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Col4a2
collagen type IV alpha 2 chain
decreases expression
ISO
apocarotenal results in decreased expression of COL4A2 mRNA
CTD
PMID:17034753
NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
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Crabp2
cellular retinoic acid binding protein 2
decreases expression
ISO
apocarotenal results in decreased expression of CRABP2 mRNA
CTD
PMID:17034753
NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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Ctsb
cathepsin B
decreases expression
ISO
apocarotenal results in decreased expression of CTSB mRNA
CTD
PMID:17034753
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Cxcl12
C-X-C motif chemokine ligand 12
increases expression
ISO
apocarotenal results in increased expression of CXCL12 mRNA
CTD
PMID:17034753
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcl6
C-X-C motif chemokine ligand 6
increases expression
ISO
apocarotenal results in increased expression of CXCL6 mRNA
CTD
PMID:17034753
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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Cxcl9
C-X-C motif chemokine ligand 9
increases expression
ISO
apocarotenal results in increased expression of CXCL9 mRNA
CTD
PMID:17034753
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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Cxcr4
C-X-C motif chemokine receptor 4
increases expression
ISO
apocarotenal results in increased expression of CXCR4 mRNA
CTD
PMID:17034753
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Dlx2
distal-less homeobox 2
increases expression
ISO
apocarotenal results in increased expression of DLX2 mRNA
CTD
PMID:17034753
NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597
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Dlx4
distal-less homeobox 4
increases expression
ISO
apocarotenal results in increased expression of DLX4 mRNA
CTD
PMID:17034753
NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,085,465...80,090,456
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Ercc2
ERCC excision repair 2, TFIIH core complex helicase subunit
decreases expression
ISO
apocarotenal results in decreased expression of ERCC2 mRNA
CTD
PMID:17034753
NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
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Ets1
ETS proto-oncogene 1, transcription factor
decreases expression
ISO
apocarotenal results in decreased expression of ETS1 mRNA
CTD
PMID:17034753
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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Fas
Fas cell surface death receptor
increases expression
ISO
apocarotenal results in increased expression of FAS mRNA
CTD
PMID:17034753
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Fasn
fatty acid synthase
decreases expression
ISO
apocarotenal results in decreased expression of FASN mRNA
CTD
PMID:17034753
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Gata6
GATA binding protein 6
increases expression
ISO
apocarotenal results in increased expression of GATA6 mRNA
CTD
PMID:17034753
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
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Gbp1
guanylate binding protein 1
increases expression
ISO
apocarotenal results in increased expression of GBP1 mRNA
CTD
PMID:17034753
NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131 Ensembl chr 2:231,398,163...231,432,131
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Gstk1
glutathione S-transferase kappa 1
decreases expression
ISO
apocarotenal results in decreased expression of GSTK1 mRNA
CTD
PMID:17034753
NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
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Gstm2
glutathione S-transferase mu 2
decreases expression
ISO
apocarotenal results in decreased expression of GSTM2 mRNA
CTD
PMID:17034753
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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Gstm4
glutathione S-transferase mu 4
decreases expression
ISO
apocarotenal results in decreased expression of GSTM4 mRNA
CTD
PMID:17034753
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
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Gstm5l
glutathione S-transferase, mu 5-like
increases expression
ISO
apocarotenal results in increased expression of GSTM5 mRNA
CTD
PMID:17034753
NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
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Gstz1
glutathione S-transferase zeta 1
decreases expression
ISO
apocarotenal results in decreased expression of GSTZ1 mRNA
CTD
PMID:17034753
NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
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Hoxa7
homeobox A7
increases expression
ISO
apocarotenal results in increased expression of HOXA7 mRNA
CTD
PMID:17034753
NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
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Hoxb6
homeo box B6
increases expression
ISO
apocarotenal results in increased expression of HOXB6 mRNA
CTD
PMID:17034753
NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
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Hoxc10
homeo box C10
increases expression
ISO
apocarotenal results in increased expression of HOXC10 mRNA
CTD
PMID:17034753
NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
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Irf8
interferon regulatory factor 8
increases expression
ISO
apocarotenal results in increased expression of IRF8 mRNA
CTD
PMID:17034753
NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
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Irx4
iroquois homeobox 4
decreases expression
ISO
apocarotenal results in decreased expression of IRX4 mRNA
CTD
PMID:17034753
NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549
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Itgb4
integrin subunit beta 4
decreases expression
ISO
apocarotenal results in decreased expression of ITGB4 mRNA
CTD
PMID:17034753
NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
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Ivl
involucrin
increases expression
ISO
apocarotenal results in increased expression of IVL mRNA
CTD
PMID:17034753
NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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Krt17
keratin 17
decreases expression
ISO
apocarotenal results in decreased expression of KRT17 mRNA
CTD
PMID:17034753
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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Krt2
keratin 2
increases expression
ISO
apocarotenal results in increased expression of KRT2 mRNA
CTD
PMID:17034753
NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:132,940,862...132,947,963
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Krt7
keratin 7
affects expression
ISO
apocarotenal affects the expression of KRT7 mRNA
CTD
PMID:17034753
NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
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Lhx3
LIM homeobox 3
increases expression
ISO
apocarotenal results in increased expression of LHX3 mRNA
CTD
PMID:17034753
NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
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LOC100912356
interferon alpha-1-like
increases expression
ISO
apocarotenal results in increased expression of IFNA5 mRNA
CTD
PMID:17034753
NCBI chr 5:103,227,820...103,230,500
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Mcl1
MCL1 apoptosis regulator, BCL2 family member
affects expression
ISO
apocarotenal affects the expression of MCL1 mRNA
CTD
PMID:17034753
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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Meis2
Meis homeobox 2
increases expression
ISO
apocarotenal results in increased expression of MEIS2 mRNA
CTD
PMID:17034753
NCBI chr 3:102,742,904...102,944,833
Ensembl chr 3:102,742,900...102,949,696
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Meox1
mesenchyme homeobox 1
increases expression
ISO
apocarotenal results in increased expression of MEOX1 mRNA
CTD
PMID:17034753
NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
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Mnx1
motor neuron and pancreas homeobox 1
increases expression
ISO
apocarotenal results in increased expression of MNX1 mRNA
CTD
PMID:17034753
NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
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Msh5
mutS homolog 5
increases expression
ISO
apocarotenal results in increased expression of MSH5 mRNA
CTD
PMID:17034753
NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
increases expression
ISO
apocarotenal results in increased expression of MUC5AC mRNA
CTD
PMID:17034753
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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Nos1
nitric oxide synthase 1
increases expression
ISO
apocarotenal results in increased expression of NOS1 mRNA
CTD
PMID:17034753
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Olr1
oxidized low density lipoprotein receptor 1
increases expression
ISO
apocarotenal results in increased expression of OLR1 mRNA
CTD
PMID:17034753
NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
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Pcdhgc3
protocadherin gamma subfamily C, 3
increases expression
ISO
apocarotenal results in increased expression of PCDHGC3 mRNA
CTD
PMID:17034753
NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
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Plscr1
phospholipid scramblase 1
increases expression
ISO
apocarotenal results in increased expression of PLSCR1 mRNA
CTD
PMID:17034753
NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
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Plscr3
phospholipid scramblase 3
increases expression
ISO
apocarotenal results in increased expression of PLSCR3 mRNA
CTD
PMID:17034753
NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709
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Plscr4
phospholipid scramblase 4
increases expression
ISO
apocarotenal results in increased expression of PLSCR4 mRNA
CTD
PMID:17034753
NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
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Rad51ap1
RAD51 associated protein 1
increases expression
ISO
apocarotenal results in increased expression of RAD51AP1 mRNA
CTD
PMID:17034753
NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524
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Rad51d
RAD51 paralog D
increases expression
ISO
apocarotenal results in increased expression of RAD51D mRNA
CTD
PMID:17034753
NCBI chr10:67,805,720...67,824,452
Ensembl chr10:67,740,712...67,824,434
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Rara
retinoic acid receptor, alpha
decreases expression
ISO
apocarotenal results in decreased expression of RARA mRNA
CTD
PMID:17034753
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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Rarb
retinoic acid receptor, beta
increases expression
ISO
apocarotenal results in increased expression of RARB mRNA
CTD
PMID:17034753
NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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Rarres1
retinoic acid receptor responder 1
increases expression
ISO
apocarotenal results in increased expression of RARRES1 mRNA
CTD
PMID:17034753
NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
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Six6
SIX homeobox 6
increases expression
ISO
apocarotenal results in increased expression of SIX6 mRNA
CTD
PMID:17034753
NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:91,634,568...91,639,548
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Sod1
superoxide dismutase 1
decreases expression
ISO
apocarotenal results in decreased expression of SOD1 mRNA
CTD
PMID:17034753
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sptlc2
serine palmitoyltransferase, long chain base subunit 2
affects expression
ISO
apocarotenal affects the expression of SPTLC2 mRNA
CTD
PMID:17034753
NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
ISO
apocarotenal results in increased expression of SREBF1 mRNA
CTD
PMID:17034753
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tgm4
transglutaminase 4
increases expression
ISO
apocarotenal results in increased expression of TGM4 mRNA
CTD
PMID:17034753
NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:122,689,429...122,726,463
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Tnfrsf9
TNF receptor superfamily member 9
increases expression
ISO
apocarotenal results in increased expression of TNFRSF9 mRNA
CTD
PMID:17034753
NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
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Tnfsf10
TNF superfamily member 10
increases expression
ISO
apocarotenal results in increased expression of TNFSF10 mRNA
CTD
PMID:17034753
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Txndc9
thioredoxin domain containing 9
increases expression
ISO
apocarotenal results in increased expression of TXNDC9 mRNA
CTD
PMID:17034753
NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279 Ensembl chr 9:40,211,412...40,384,279
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Xrcc3
X-ray repair cross complementing 3
increases expression
ISO
apocarotenal results in increased expression of XRCC3 mRNA
CTD
PMID:17034753
NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19874
chemical entity
19872
atom
19872
nonmetal atom
19794
carbon atom
19748
organic molecular entity
19748
isoprenoid
14063
apo carotenoid
123
apo carotenoid triterpenoid
76
(3R)-3-hydroxy-8'-apo-beta-carotenal
0
(3R)-3-hydroxy-8'-apo-beta-carotenol
0
4,4'-diapo-zeta-carotene +
0
4,4'-diapolycopen-4-al
0
4,4'-diapolycopen-4-oic acid
0
4,4'-diapolycopenedioic acid
0
4,4'-diaponeurosporenal
0
4,4'-diaponeurosporene
0
4,4'-diaponeurosporenoic acid
0
4,4'-diapophytoene +
0
4,4'-diapophytofluene +
0
8'-apo-beta,psi-caroten-8'-al
76
8'-apo-beta-carotenol
0
staphyloxanthin
0
Path 2
CHEBI ontology
19874
subatomic particle
19872
composite particle
19872
hadron
19872
baryon
19872
nucleon
19872
atomic nucleus
19872
atom
19872
main group element atom
19811
main group molecular entity
19811
s-block molecular entity
19647
hydrogen molecular entity
19628
hydrides
19139
organic hydride
18687
organic fundamental parent
18687
hydrocarbon
18438
terpene
14063
tetraterpene
599
carotene
599
carotenoid
599
apo carotenoid triterpenoid
76
(3R)-3-hydroxy-8'-apo-beta-carotenal
0
(3R)-3-hydroxy-8'-apo-beta-carotenol
0
4,4'-diapo-zeta-carotene +
0
4,4'-diapolycopen-4-al
0
4,4'-diapolycopen-4-oic acid
0
4,4'-diapolycopenedioic acid
0
4,4'-diaponeurosporenal
0
4,4'-diaponeurosporene
0
4,4'-diaponeurosporenoic acid
0
4,4'-diapophytoene +
0
4,4'-diapophytofluene +
0
8'-apo-beta,psi-caroten-8'-al
76
8'-apo-beta-carotenol
0
staphyloxanthin
0