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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dichlorobiphenyl
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Accession:CHEBI:36718 term browser browse the term
Definition:Any polychlorobiphenyl with molecular formula C12H8Cl2.
Synonyms:exact_synonym: dichloro-1,1'-biphenyl
 related_synonym: Formula=C12H8Cl2



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2,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
2,4'-dichlorobiphenyl binds to AR protein
2,4'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD PMID:14565775 PMID:18324785 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,4'-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
affects binding
ISO 2,4'-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
2,4'-dichlorobiphenyl metabolite binds to SULT2A1 protein
CTD PMID:24508592 NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
2,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,5-dichlorobiphenyl analog results in increased activity of NR1I3 protein; 2,5-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein affects the metabolism of Dehydroepiandrosterone]; 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone] CTD PMID:17112228 PMID:24508592 NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
2,6-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2,6-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
3,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 3,5-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases response to substance EXP MAPK1 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases response to substance EXP MAPK3 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Serpina7 serpin family A member 7 multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to SERPINA7 protein] CTD PMID:16478101 NCBI chr  X:107,452,044...107,510,958
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding
multiple interactions
ISO 3,5-dichlorobiphenyl metabolite binds to SULT2A1 protein
3,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
CTD PMID:24508592 NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Ttr transthyretin multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to TTR protein] CTD PMID:16478101 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008
JBrowse link
4,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO 4,4'-dichlorobiphenyl results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19879
    role 19850
      chemical role 19480
        environmental contaminant 18860
          persistent organic pollutant 16781
            polychlorobiphenyl 6032
              dichlorobiphenyl 8
                2,4'-dichlorobiphenyl 3
                2,5-dichlorobiphenyl 2
                2,6-dichlorobiphenyl 1
                3,5-dichlorobiphenyl 6
                4,4'-dichlorobiphenyl 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19879
    subatomic particle 19877
      composite particle 19877
        hadron 19877
          baryon 19877
            nucleon 19877
              atomic nucleus 19877
                atom 19877
                  main group element atom 19816
                    main group molecular entity 19816
                      s-block molecular entity 19651
                        hydrogen molecular entity 19633
                          hydrides 19147
                            organic hydride 18697
                              organic fundamental parent 18697
                                hydrocarbon 18448
                                  halohydrocarbon 15854
                                    haloarene 6420
                                      chloroarene 6034
                                        chlorobiphenyl 6034
                                          polychlorobiphenyl 6032
                                            dichlorobiphenyl 8
                                              2,4'-dichlorobiphenyl 3
                                              2,5-dichlorobiphenyl 2
                                              2,6-dichlorobiphenyl 1
                                              3,5-dichlorobiphenyl 6
                                              4,4'-dichlorobiphenyl 1
paths to the root