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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dichlorobiphenyl
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Accession:CHEBI:36718 term browser browse the term
Definition:Any polychlorobiphenyl with molecular formula C12H8Cl2.
Synonyms:exact_synonym: dichloro-1,1'-biphenyl
 related_synonym: Formula=C12H8Cl2



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2,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions
ISO 2,4'-dichlorobiphenyl binds to AR protein
2,4'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]
CTD PMID:14565775 PMID:18324785 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,4'-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions
affects binding
ISO 2,4'-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
2,4'-dichlorobiphenyl metabolite binds to SULT2A1 protein
CTD PMID:24508592 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
2,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,5-dichlorobiphenyl analog results in increased activity of NR1I3 protein; 2,5-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions ISO 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein affects the metabolism of Dehydroepiandrosterone]; 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone] CTD PMID:17112228 PMID:24508592 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
2,6-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2,6-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
3,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 3,5-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases response to substance ISO MAPK1 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases response to substance ISO MAPK3 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Serpina7 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to SERPINA7 protein] CTD PMID:16478101 NCBI chr  X:137,979,998...137,985,985
Ensembl chr  X:137,980,006...137,985,985
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 affects binding
multiple interactions
ISO 3,5-dichlorobiphenyl metabolite binds to SULT2A1 protein
3,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
CTD PMID:24508592 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Ttr transthyretin multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to TTR protein] CTD PMID:16478101 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378
JBrowse link
4,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO 4,4'-dichlorobiphenyl results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr16:19,472,131...19,525,115
Ensembl chr16:19,472,128...19,525,125
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    role 22293
      chemical role 21547
        environmental contaminant 20144
          persistent organic pollutant 17806
            polychlorobiphenyl 6305
              dichlorobiphenyl 8
                2,4'-dichlorobiphenyl 3
                2,5-dichlorobiphenyl 2
                2,6-dichlorobiphenyl 1
                3,5-dichlorobiphenyl 6
                4,4'-dichlorobiphenyl 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22184
                    main group molecular entity 22184
                      s-block molecular entity 21804
                        hydrogen molecular entity 21721
                          hydrides 20775
                            organic hydride 20321
                              organic fundamental parent 20321
                                hydrocarbon 19903
                                  halohydrocarbon 16593
                                    haloarene 6677
                                      chloroarene 6307
                                        chlorobiphenyl 6307
                                          polychlorobiphenyl 6305
                                            dichlorobiphenyl 8
                                              2,4'-dichlorobiphenyl 3
                                              2,5-dichlorobiphenyl 2
                                              2,6-dichlorobiphenyl 1
                                              3,5-dichlorobiphenyl 6
                                              4,4'-dichlorobiphenyl 1
paths to the root