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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dichlorobiphenyl
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Accession:CHEBI:36718 term browser browse the term
Definition:Any polychlorobiphenyl with molecular formula C12H8Cl2.
Synonyms:exact_synonym: dichloro-1,1'-biphenyl
 related_synonym: Formula=C12H8Cl2


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2,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions		 EXP
ISO		 2,4'-dichlorobiphenyl binds to AR protein
2,4'-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein]		 CTD PMID:14565775 PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,4'-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
affects binding		 ISO 2,4'-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]
2,4'-dichlorobiphenyl metabolite binds to SULT2A1 protein		 CTD PMID:24508592 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
2,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,5-dichlorobiphenyl analog results in increased activity of NR1I3 protein; 2,5-dichlorobiphenyl results in increased activity of NR1I3 protein CTD PMID:26231822 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions ISO 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein affects the metabolism of Dehydroepiandrosterone]; 2,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone] CTD PMID:17112228 PMID:24508592 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
2,6-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 2,6-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
3,5-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 3,5-dichlorobiphenyl inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases response to substance EXP MAPK1 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases response to substance EXP MAPK3 protein modified form results in increased susceptibility to 3,5-dichlorobiphenyl analog CTD PMID:19631230 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Serpina7 serpin family A member 7 multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to SERPINA7 protein] CTD PMID:16478101 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 affects binding
multiple interactions		 ISO 3,5-dichlorobiphenyl metabolite binds to SULT2A1 protein
3,5-dichlorobiphenyl metabolite inhibits the reaction [SULT2A1 protein results in increased sulfation of Dehydroepiandrosterone]		 CTD PMID:24508592 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Ttr transthyretin multiple interactions ISO 3,5-dichlorobiphenyl metabolite inhibits the reaction [Thyroxine binds to TTR protein] CTD PMID:16478101 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
4,4'-dichlorobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO 4,4'-dichlorobiphenyl results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      chemical role 19473
        environmental contaminant 18852
          persistent organic pollutant 16768
            polychlorobiphenyl 6030
              dichlorobiphenyl 8
                2,4'-dichlorobiphenyl 3
                2,5-dichlorobiphenyl 2
                2,6-dichlorobiphenyl 1
                3,5-dichlorobiphenyl 6
                4,4'-dichlorobiphenyl 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            organic hydride 18687
                              organic fundamental parent 18687
                                hydrocarbon 18438
                                  halohydrocarbon 15850
                                    haloarene 6418
                                      chloroarene 6032
                                        chlorobiphenyl 6032
                                          polychlorobiphenyl 6030
                                            dichlorobiphenyl 8
                                              2,4'-dichlorobiphenyl 3
                                              2,5-dichlorobiphenyl 2
                                              2,6-dichlorobiphenyl 1
                                              3,5-dichlorobiphenyl 6
                                              4,4'-dichlorobiphenyl 1
paths to the root