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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:interferon inducer
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Accession:CHEBI:36710 term browser browse the term
Definition:An agent that promotes the production and release of interferons.
Synonyms:related_synonym: interferon inducers


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imiquimod term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation 		ISO epigallocatechin gallate inhibits the reaction [Imiquimod results in increased phosphorylation of AKT1 protein] CTD PMID:24990399 PMID:29402411 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases expression ISO imiquimod results in decreased expression of APEX1 mRNA CTD PMID:21878529 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO imiquimod results in decreased expression of BCL2 protein CTD PMID:20033192 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO imiquimod results in decreased expression of BLM mRNA CTD PMID:21878529 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:143,819,090...143,905,210 		JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO imiquimod results in decreased expression of BRCA2 mRNA CTD PMID:21878529 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Imiquimod results in increased expression of BST2 protein CTD PMID:31093508 NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression 		ISO evodiamine inhibits the reaction [Imiquimod results in increased expression of CALCA mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of CALCA protein]
Imiquimod results in increased expression of CALCA mRNA; Imiquimod results in increased expression of CALCA protein 		CTD PMID:38948922 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Casp1 caspase 1 increases activity
multiple interactions 		ISO Imiquimod results in increased activity of CASP1 protein
[Dronabinol inhibits the reaction [Imiquimod results in increased activity of CASP1 protein]] which affects the localization of IL1B protein; Dronabinol inhibits the reaction [Imiquimod results in increased activity of CASP1 protein]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased cleavage of CASP1 protein; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased cleavage of CASP1 protein] 		CTD PMID:31383729 PMID:36577999 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage 		ISO imiquimod results in increased activity of CASP3 protein
imiquimod results in increased cleavage of CASP3 protein 		CTD PMID:12902443 PMID:20033192 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO Imiquimod results in increased secretion of CCL2 protein CTD PMID:34740670 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Imiquimod results in increased expression of CD274 protein CTD PMID:31093508 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951 		JBrowse link
G Cd40 CD40 molecule increases expression
multiple interactions 		ISO Imiquimod results in increased expression of CD40 protein
LGMN gene mutant form inhibits the reaction [Imiquimod results in increased expression of CD40 protein] 		CTD PMID:22916010 PMID:31093508 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd80 Cd80 molecule increases expression ISO Imiquimod results in increased expression of CD80 protein CTD PMID:31093508 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression 		ISO [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased expression of CD86 protein]; Tetrachlorodibenzodioxin promotes the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein] CTD PMID:21097750 PMID:22916010 PMID:31093508 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO imiquimod results in decreased expression of CHAF1A mRNA CTD PMID:21878529 NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868 		JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B decreases expression ISO imiquimod results in decreased expression of CHAF1B mRNA CTD PMID:21878529 NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733 		JBrowse link
G Ctsb cathepsin B increases activity ISO Imiquimod results in increased activity of CTSB protein CTD PMID:22916010 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Ctsk cathepsin K increases activity ISO Imiquimod results in increased activity of CTSK protein CTD PMID:22916010 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Ctsl cathepsin L increases activity ISO Imiquimod results in increased activity of CTSL protein CTD PMID:22916010 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Ctss cathepsin S increases activity ISO Imiquimod results in increased activity of CTSS protein CTD PMID:22916010 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein; Particulate Matter inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein]; Vehicle Emissions inhibits the reaction [[Pam(3)CSK(4) peptide co-treated with Antigens, Bacterial co-treated with Poly I-C co-treated with Lipopolysaccharides co-treated with FSL-1 lipoprotein, synthetic co-treated with imiquimod co-treated with Polyribonucleotides co-treated with ProMune] results in increased expression of CXCL10 protein] CTD PMID:28655636 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion
increases expression
multiple interactions 		ISO Imiquimod results in increased secretion of CXCL1 protein
Imiquimod results in increased expression of CXCL1 mRNA
hispidulin inhibits the reaction [Imiquimod results in increased expression of CXCL1 mRNA] 		CTD PMID:22916010 PMID:32679548 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases metabolic processing
increases chemical synthesis
multiple interactions
affects metabolic processing 		ISO CYP1A1 protein results in increased metabolism of Imiquimod
CYP1A1 protein results in increased chemical synthesis of Imiquimod metabolite
[CYP1A1 protein results in increased metabolism of Imiquimod] which results in increased chemical synthesis of Imiquimod metabolite
CYP1A1 protein affects the metabolism of Imiquimod
CYP1A1 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod] 		CTD PMID:31111189 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases metabolic processing
increases chemical synthesis
affects metabolic processing 		ISO [CYP1A2 protein results in increased metabolism of Imiquimod] which results in increased chemical synthesis of Imiquimod metabolite
CYP1A2 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod]
CYP1A2 protein results in increased chemical synthesis of Imiquimod metabolite
CYP1A2 protein affects the metabolism of Imiquimod 		CTD PMID:31111189 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases metabolic processing ISO CYP2C19 protein results in increased metabolism of Imiquimod CTD PMID:31111189 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of Imiquimod CTD PMID:31111189 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Dnm3 dynamin 3 increases expression ISO Imiquimod results in increased expression of DNM3 mRNA CTD PMID:38760990 NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO imiquimod results in decreased expression of ERCC2 mRNA CTD PMID:21878529 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease increases expression ISO imiquimod results in increased expression of ERCC5 mRNA CTD PMID:21878529 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084 		JBrowse link
G Fancl FA complementation group L decreases expression ISO imiquimod results in decreased expression of FANCL mRNA CTD PMID:21878529 NCBI chr14:104,449,403...104,515,297
Ensembl chr14:104,394,590...104,515,297 		JBrowse link
G Fbh1 F-box DNA helicase 1 decreases expression ISO imiquimod results in decreased expression of FBH1 mRNA CTD PMID:21878529 NCBI chr17:71,659,351...71,697,431
Ensembl chr17:71,659,249...71,697,432 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO imiquimod results in decreased expression of FGF2 CTD PMID:16368197 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Gsdmd gasdermin D multiple interactions ISO [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased cleavage of GSDMD protein; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased cleavage of GSDMD protein] CTD PMID:36577999 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gtf2h3 general transcription factor IIH subunit 3 decreases expression ISO imiquimod results in decreased expression of GTF2H3 mRNA CTD PMID:21878529 NCBI chr12:37,669,995...37,687,505
Ensembl chr12:37,669,997...37,686,466 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 decreases expression ISO imiquimod results in decreased expression of GTF2H4 mRNA CTD PMID:21878529 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760 		JBrowse link
G Gzmb granzyme B multiple interactions ISO Imiquimod results in increased expression of and results in increased secretion of GZMB protein CTD PMID:31093508 NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Imiquimod results in decreased expression of H2AX mRNA CTD PMID:21878529 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ICAM1 protein; Tetrachlorodibenzodioxin promotes the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ICAM1 protein] CTD PMID:21097750 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Hydroxychloroquine co-treated with Imiquimod] results in increased secretion of IL10 protein CTD PMID:31082466 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il11 interleukin 11 multiple interactions
decreases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL11 mRNA] CTD PMID:31054998 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915 		JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 multiple interactions
decreases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL11RA1 mRNA] CTD PMID:31054998 NCBI chr 5:61,727,650...61,737,265
Ensembl chr 5:61,727,931...61,737,264 		JBrowse link
G Il12a interleukin 12A multiple interactions
increases secretion 		ISO [imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]; Tetrachlorodibenzodioxin inhibits the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]
Imiquimod results in increased secretion of IL12A protein 		CTD PMID:21097750 PMID:31093508 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression
increases secretion 		ISO [Imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL12B mRNA]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased secretion of IL12B protein]; Tetrachlorodibenzodioxin inhibits the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:21097750 PMID:22916010 PMID:31054998 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL13RA1 mRNA] CTD PMID:31054998 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Imiquimod results in increased expression of IL13RA2 mRNA CTD PMID:31054998 NCBI chr  X:115,814,620...115,886,080
Ensembl chr  X:115,814,622...115,841,455 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases secretion
increases expression 		ISO (+)-JQ1 compound inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]; (+)-JQ1 compound inhibits the reaction [Imiquimod results in increased secretion of IL17A protein]; Chloroquine inhibits the reaction [Imiquimod results in increased expression of IL17A protein]; evodiamine inhibits the reaction [Imiquimod results in increased expression of IL17A protein]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL17A protein]; hispidulin inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]; Resveratrol inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]; SR 1078 inhibits the reaction [(+)-JQ1 compound inhibits the reaction [Imiquimod results in increased expression of IL17A mRNA]]; SR 1078 inhibits the reaction [(+)-JQ1 compound inhibits the reaction [Imiquimod results in increased secretion of IL17A protein]]
imiquimod results in increased secretion of IL17A protein
Imiquimod results in increased expression of IL17A mRNA; Imiquimod results in increased expression of IL17A protein 		CTD PMID:25965695 PMID:26149470 PMID:31054998 PMID:32679548 PMID:36002070 More... NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il17b interleukin 17B decreases expression
multiple interactions 		ISO Imiquimod results in decreased expression of IL17B mRNA
ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL17B mRNA] 		CTD PMID:31054998 NCBI chr18:57,411,532...57,415,903
Ensembl chr18:57,411,532...57,415,903 		JBrowse link
G Il17rb interleukin 17 receptor B decreases expression
multiple interactions 		ISO Imiquimod results in decreased expression of IL17RB mRNA
ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL17RB mRNA] 		CTD PMID:31054998 NCBI chr16:5,186,961...5,200,657
Ensembl chr16:5,186,961...5,200,694 		JBrowse link
G Il18 interleukin 18 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL18 mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] 		CTD PMID:31054998 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il18bp interleukin 18 binding protein increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL18BP mRNA
hispidulin inhibits the reaction [Imiquimod results in increased expression of IL18BP mRNA] 		CTD PMID:32679548 NCBI chr 1:165,784,916...165,787,990
Ensembl chr 1:165,784,069...165,786,955 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18RAP mRNA] CTD PMID:31054998 NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:50,263,733...50,296,583 		JBrowse link
G Il19 interleukin 19 increases expression
multiple interactions 		ISO imiquimod results in increased expression of IL19 mRNA
resveratrol inhibits the reaction [imiquimod results in increased expression of IL19 mRNA] 		CTD PMID:25965695 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1A mRNA] CTD PMID:31054998 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
increases expression 		ISO Imiquimod results in increased secretion of IL1B protein
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Imiquimod] results in increased secretion of IL1B protein; Chloroquine inhibits the reaction [Imiquimod results in increased expression of IL1B protein]; Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Imiquimod] results in increased secretion of IL1B protein]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1B mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL1B protein]; hispidulin inhibits the reaction [Imiquimod results in increased expression of IL1B mRNA]; lonidamine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Imiquimod] results in increased secretion of IL1B protein]
Imiquimod results in increased expression of IL1B mRNA; Imiquimod results in increased expression of IL1B protein
[Dronabinol inhibits the reaction [Imiquimod results in increased activity of CASP1 protein]] which affects the localization of IL1B protein; Cannabidiol inhibits the reaction [Imiquimod results in increased secretion of IL1B protein]; Dronabinol inhibits the reaction [Imiquimod results in increased expression of IL1B mRNA]; Dronabinol inhibits the reaction [Imiquimod results in increased secretion of IL1B protein]; JHW 015 inhibits the reaction [Imiquimod results in increased secretion of IL1B protein] 		CTD PMID:18403674 PMID:31054998 PMID:31082466 PMID:31383729 PMID:32679548 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1f10 interleukin 1 family member 10 decreases expression
multiple interactions 		ISO Imiquimod results in decreased expression of IL1F10 mRNA
ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL1F10 mRNA] 		CTD PMID:31054998 NCBI chr 3:27,470,798...27,473,726
Ensembl chr 3:27,470,798...27,473,726 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein increases expression ISO Imiquimod results in increased expression of IL1RAP mRNA CTD PMID:31054998 NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342 		JBrowse link
G Il2 interleukin 2 increases secretion ISO Imiquimod results in increased secretion of IL2 protein CTD PMID:34740670 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il20 interleukin 20 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL20 mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20 mRNA] 		CTD PMID:31054998 NCBI chr13:44,933,249...44,936,893
Ensembl chr13:44,933,249...44,936,893 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL20RB mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL20RB mRNA] 		CTD PMID:31054998 NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363 		JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL22RA1 mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL22RA1 mRNA] 		CTD PMID:31054998 NCBI chr 5:153,245,067...153,269,865
Ensembl chr 5:153,245,002...153,271,683 		JBrowse link
G Il23a interleukin 23 subunit alpha increases secretion
increases expression
multiple interactions 		ISO imiquimod results in increased secretion of IL23A protein
Imiquimod results in increased expression of IL23A mRNA; Imiquimod results in increased expression of IL23A protein
evodiamine inhibits the reaction [Imiquimod results in increased expression of IL23A protein]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL23A mRNA]; ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL23A protein] 		CTD PMID:25965695 PMID:26149470 PMID:31054998 PMID:38948922 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il27 interleukin 27 multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL27 mRNA] CTD PMID:31054998 NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:190,603,522...190,609,258 		JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL33 mRNA] CTD PMID:31054998 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il36a interleukin 36, alpha increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL36A mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36A mRNA] 		CTD PMID:31054998 NCBI chr 3:27,395,146...27,399,695
Ensembl chr 3:27,395,146...27,399,695 		JBrowse link
G Il36b interleukin 36, beta increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL36B mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36B mRNA] 		CTD PMID:31054998 NCBI chr 3:27,422,980...27,521,344
Ensembl chr 3:27,423,171...27,428,678 		JBrowse link
G Il36g interleukin 36, gamma multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36G mRNA] CTD PMID:31054998 NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:27,346,670...27,352,834 		JBrowse link
G Il36rn interleukin 36 receptor antagonist multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL36RN mRNA] CTD PMID:31054998 NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:27,442,709...27,449,306 		JBrowse link
G Il4 interleukin 4 increases secretion ISO Imiquimod results in increased secretion of IL4 protein CTD PMID:34740670 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression 		ISO [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased secretion of IL6 protein; concanamycin B inhibits the reaction [Imiquimod results in increased secretion of IL6 protein]; hispidulin inhibits the reaction [Imiquimod results in increased expression of IL6 mRNA]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased secretion of IL6 protein]; MV026630 inhibits the reaction [Imiquimod results in increased secretion of IL6 protein]
[Hydroxychloroquine co-treated with Imiquimod] results in increased secretion of IL6 protein; Cannabidiol promotes the reaction [Imiquimod results in increased secretion of IL6 protein] 		CTD PMID:21097750 PMID:22916010 PMID:31082466 PMID:31093508 PMID:31383729 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il7 interleukin 7 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IL7 mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL7 mRNA] 		CTD PMID:31054998 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Il7r interleukin 7 receptor multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL7R mRNA] CTD PMID:31054998 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027 		JBrowse link
G Il9r interleukin 9 receptor decreases expression
multiple interactions 		ISO Imiquimod results in decreased expression of IL9R mRNA
ferulic acid inhibits the reaction [Imiquimod results in decreased expression of IL9R mRNA] 		CTD PMID:31054998 NCBI chr10:15,936,156...15,947,613
Ensembl chr10:15,936,156...15,947,613 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions
increases expression 		ISO ferulic acid inhibits the reaction [Imiquimod results in increased expression of IRAK2 mRNA] CTD PMID:31054998 NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of IRAK3 mRNA
ferulic acid inhibits the reaction [Imiquimod results in increased expression of IRAK3 mRNA] 		CTD PMID:31054998 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO [imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ITGAX protein; Tetrachlorodibenzodioxin inhibits the reaction [[imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ITGAX protein] CTD PMID:21097750 NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151 		JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO imiquimod results in decreased expression of KIF22 mRNA CTD PMID:21878529 NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:191,065,875...191,080,878 		JBrowse link
G Lgmn legumain increases activity
multiple interactions 		ISO Imiquimod results in increased activity of LGMN protein
LGMN gene mutant form inhibits the reaction [Imiquimod results in increased cleavage of TLR7 protein]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased expression of CD40 protein]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased expression of CD86 protein]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased secretion of IL12B protein]; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased secretion of IL6 protein] 		CTD PMID:22916010 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328 		JBrowse link
G Lig1 DNA ligase 1 decreases expression ISO imiquimod results in decreased expression of LIG1 mRNA CTD PMID:21878529 NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708 		JBrowse link
G Lrch4 leucine rich repeats and calponin homology domain containing 4 multiple interactions ISO LRCH4 protein promotes the reaction [Imiquimod results in increased expression of TNF protein] CTD PMID:30523158 NCBI chr12:24,694,364...24,709,354
Ensembl chr12:24,694,370...24,706,412 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO imiquimod results in decreased phosphorylation of MAPK1 protein CTD PMID:20033192 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO imiquimod results in decreased phosphorylation of MAPK3 protein CTD PMID:20033192 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mlh1 mutL homolog 1 decreases expression ISO imiquimod results in decreased expression of MLH1 mRNA CTD PMID:21878529 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO imiquimod results in decreased activity of MMP9 protein CTD PMID:14708627 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase decreases expression ISO imiquimod results in decreased expression of MPG mRNA CTD PMID:21878529 NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052 		JBrowse link
G Mpo myeloperoxidase increases activity
multiple interactions
increases expression 		ISO imiquimod results in increased activity of MPO protein
(+)-JQ1 compound inhibits the reaction [Imiquimod results in increased activity of MPO protein]; hispidulin inhibits the reaction [Imiquimod results in increased expression of MPO protein]; SR 1078 inhibits the reaction [(+)-JQ1 compound inhibits the reaction [Imiquimod results in increased activity of MPO protein]] 		CTD PMID:26149470 PMID:32679548 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease decreases expression ISO imiquimod results in decreased expression of MRE11A mRNA CTD PMID:21878529 NCBI chr 8:19,900,211...19,961,906
Ensembl chr 8:19,913,772...19,961,904 		JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO imiquimod results in decreased expression of MSH2 mRNA CTD PMID:21878529 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Ngf nerve growth factor increases expression
multiple interactions 		ISO Imiquimod results in increased expression of NGF mRNA; Imiquimod results in increased expression of NGF protein
evodiamine inhibits the reaction [Imiquimod results in increased expression of NGF mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of NGF protein] 		CTD PMID:38948922 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nudt1 nudix hydrolase 1 decreases expression ISO imiquimod results in decreased expression of NUDT1 mRNA CTD PMID:21878529 NCBI chr12:19,416,411...19,423,448
Ensembl chr12:19,416,411...19,424,158 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [resveratrol co-treated with imiquimod] results in increased expression of PCK1 mRNA CTD PMID:25965695 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions 		ISO Imiquimod results in increased expression of PCNA protein
Chloroquine inhibits the reaction [Imiquimod results in increased expression of PCNA protein] 		CTD PMID:36002070 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pmel premelanosome protein increases expression ISO Imiquimod results in increased expression of PMEL protein CTD PMID:38760990 NCBI chr 7:1,721,948...1,733,248
Ensembl chr 7:1,722,297...1,733,248 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component decreases expression ISO imiquimod results in decreased expression of PMS2 mRNA CTD PMID:21878529 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit decreases expression ISO imiquimod results in decreased expression of POLE mRNA CTD PMID:21878529 NCBI chr12:52,005,155...52,053,761
Ensembl chr12:52,005,155...52,053,662 		JBrowse link
G Poll DNA polymerase lambda decreases expression ISO imiquimod results in decreased expression of POLL mRNA CTD PMID:21878529 NCBI chr 1:254,349,229...254,357,689
Ensembl chr 1:254,349,231...254,358,020 		JBrowse link
G Pomc proopiomelanocortin increases expression ISO Imiquimod results in increased expression of POMC protein CTD PMID:38760990 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [resveratrol co-treated with imiquimod] results in decreased expression of PPP1R3C mRNA CTD PMID:25965695 NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835 		JBrowse link
G Prkch protein kinase C, eta increases expression ISO Imiquimod results in increased expression of PRKCH mRNA CTD PMID:38760990 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO imiquimod results in decreased expression of RAD51AP1 mRNA CTD PMID:21878529 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680 		JBrowse link
G Rad51d RAD51 paralog D decreases expression ISO imiquimod results in decreased expression of RAD51D mRNA CTD PMID:21878529 NCBI chr10:68,303,350...68,322,002
Ensembl chr10:68,238,273...68,321,902 		JBrowse link
G Rad54l RAD54 like decreases expression ISO imiquimod results in decreased expression of RAD54L mRNA CTD PMID:21878529 NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:134,811,532...134,841,425 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase decreases expression ISO Imiquimod results in decreased expression of RAD51D mRNA CTD PMID:21878529
G Rorc RAR-related orphan receptor C increases expression
multiple interactions 		ISO imiquimod results in increased expression of RORC mRNA; imiquimod results in increased expression of RORC protein
(+)-JQ1 compound inhibits the reaction [imiquimod results in increased expression of RORC mRNA]; (+)-JQ1 compound inhibits the reaction [imiquimod results in increased expression of RORC protein] 		CTD PMID:26149470 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO imiquimod results in decreased expression of RUVBL2 mRNA CTD PMID:21878529 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720 		JBrowse link
G S100a1 S100 calcium binding protein A1 increases expression ISO Imiquimod results in increased expression of S100A1 protein CTD PMID:38760990 NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:178,291,503...178,296,346 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO imiquimod inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO imiquimod inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Ssrp1 structure specific recognition protein 1 decreases expression ISO imiquimod results in decreased expression of SSRP1 mRNA CTD PMID:21878529 NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:90,530,829...90,541,129 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO imiquimod results in increased expression of STAT3 mRNA CTD PMID:26149470 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression 		ISO evodiamine inhibits the reaction [Imiquimod results in increased expression of TAC1 mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of TAC1 protein]
Imiquimod results in increased expression of TAC1 mRNA; Imiquimod results in increased expression of TAC1 protein 		CTD PMID:38948922 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases secretion ISO Imiquimod results in increased secretion of TGFB1 protein CTD PMID:34740670 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO imiquimod results in increased expression of TIMP1 protein CTD PMID:14708627 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tlr7 toll-like receptor 7 multiple interactions
affects binding
increases cleavage 		ISO [Imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]; [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein; [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ICAM1 protein; [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ITGAX protein; [Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased secretion of IL6 protein; LGMN gene mutant form inhibits the reaction [Imiquimod results in increased cleavage of TLR7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] results in increased secretion of [IL12A protein binds to IL12B protein]]; Tetrachlorodibenzodioxin inhibits the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ITGAX protein]; Tetrachlorodibenzodioxin promotes the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of CD86 protein]; Tetrachlorodibenzodioxin promotes the reaction [[Imiquimod binds to and results in increased activity of TLR7 protein] which results in increased expression of ICAM1 protein]
Imiquimod binds to TLR7 protein 		CTD PMID:21097750 PMID:22916010 PMID:31093508 NCBI chr  X:30,644,324...30,670,796
Ensembl chr  X:30,644,355...30,672,151 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
decreases expression 		ISO CGP 57380 inhibits the reaction [Imiquimod results in increased expression of TNF protein]; evodiamine inhibits the reaction [Imiquimod results in increased expression of TNF protein]; hispidulin inhibits the reaction [Imiquimod results in increased expression of TNF protein]; LRCH4 protein promotes the reaction [Imiquimod results in increased expression of TNF protein]
Imiquimod results in increased expression of TNF mRNA; Imiquimod results in increased expression of TNF protein
Imiquimod results in increased secretion of TNF protein
Cannabidiol promotes the reaction [Imiquimod results in increased secretion of TNF protein]
Imiquimod results in decreased expression of TNF protein 		CTD PMID:18032482 PMID:25965695 PMID:26149470 PMID:30523158 PMID:31093508 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Trex1 three prime repair exonuclease 1 increases expression ISO imiquimod results in increased expression of TREX1 mRNA CTD PMID:21878529 NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:118,585,081...118,586,083 		JBrowse link
G Trim63 tripartite motif containing 63 multiple interactions ISO [resveratrol co-treated with imiquimod] results in increased expression of TRIM63 mRNA CTD PMID:25965695 NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of TRPV1 mRNA; Imiquimod results in increased expression of TRPV1 protein
evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV1 mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV1 protein] 		CTD PMID:38948922 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions
increases expression 		ISO evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV3 mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV3 protein]
Imiquimod results in increased expression of TRPV3 mRNA; Imiquimod results in increased expression of TRPV3 protein 		CTD PMID:38948922 NCBI chr10:58,382,054...58,413,657
Ensembl chr10:58,382,054...58,411,800 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases expression
multiple interactions 		ISO Imiquimod results in increased expression of TRPV4 mRNA; Imiquimod results in increased expression of TRPV4 protein
evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV4 mRNA]; evodiamine inhibits the reaction [Imiquimod results in increased expression of TRPV4 protein] 		CTD PMID:38948922 NCBI chr12:47,599,161...47,638,143
Ensembl chr12:47,599,035...47,638,143 		JBrowse link
G Tyr tyrosinase multiple interactions
increases activity 		ISO Imiquimod results in increased expression of and results in increased activity of TYR protein
Imiquimod results in increased activity of TYR protein 		CTD PMID:38760990 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO imiquimod results in decreased expression of UHRF1 mRNA CTD PMID:21878529 NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792 		JBrowse link
G Wrnip1 WRN helicase interacting protein 1 decreases expression ISO imiquimod results in decreased expression of WRNIP1 mRNA CTD PMID:21878529 NCBI chr17:31,830,159...31,850,408
Ensembl chr17:31,830,160...31,850,408 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO imiquimod results in increased expression of XPC mRNA CTD PMID:21878529 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305 		JBrowse link
tilorone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Tilorone results in decreased activity of ACHE protein CTD PMID:33400519 PMID:33844597 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        pharmaceutical 20359
          drug 20359
            interferon inducer 124
              imiquimod 123
              tilorone 1
              tilorone dihydrochloride 0
paths to the root