The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [ADCYAP1 protein alternative form results in decreased susceptibility to 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid]
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased degradation of GUCY1B1 protein BAY 58-2667 inhibits the reaction [1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased degradation of GUCY1B1 protein]; zinc protoporphyrin inhibits the reaction [1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased degradation of GUCY1B1 protein]
Tetrachlorodibenzodioxin results in decreased expression of AHR mRNA Tetrachlorodibenzodioxin results in increased expression of AHR protein Tetrachlorodibenzodioxin affects the localization of AHR protein
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]]
[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein; epigallocatechin gallate inhibits the reaction [[alpha-naphthoflavone co-treated with 3,4,3',4'-tetrachlorobiphenyl] results in increased activity of AHR protein]; epigallocatechin gallate inhibits the reaction [alpha-naphthoflavone results in increased activity of AHR protein]
alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A1 mRNA] alpha-naphthoflavone results in increased expression of CYP1A1 mRNA alpha-naphthoflavone results in decreased activity of CYP1A1 protein
beta-Naphthoflavone results in increased expression of CYP1A1 mRNA; beta-Naphthoflavone results in increased expression of CYP1A1 protein beta-Naphthoflavone results in increased activity of CYP1A1 protein epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; epigallocatechin gallate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
Carvedilol results in decreased expression of EDN1 protein Glyburide inhibits the reaction [Carvedilol results in decreased expression of EDN1 protein]
evodiamine results in increased expression of CASP1 mRNA 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased expression of CASP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of CASP1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of CASP1 protein]
evodiamine results in decreased expression of CHUK protein evodiamine inhibits the reaction [T-2 Toxin results in increased expression of CHUK protein]
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of CLDN1 protein]
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein]]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of GSDMD protein]
evodiamine inhibits the reaction [T-2 Toxin results in increased expression of IL18 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of IL18 protein]
evodiamine results in decreased expression of KEAP1 protein 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of KEAP1 protein]
evodiamine inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of IL1B protein] evodiamine results in decreased expression of IL1B mRNA
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide affects the reaction [evodiamine affects the reaction [T-2 Toxin affects the localization of NFE2L2 protein]]; evodiamine affects the reaction [T-2 Toxin affects the localization of NFE2L2 protein]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of NFE2L2 mRNA] evodiamine results in increased expression of NFE2L2 mRNA
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased expression of NLRP3 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of NLRP3 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of NLRP3 protein] evodiamine results in increased expression of NLRP3 mRNA
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of OCLN protein]
evodiamine inhibits the reaction [T-2 Toxin results in increased expression of PYCARD mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of PYCARD protein]
evodiamine results in decreased phosphorylation of RELA protein 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide affects the reaction [evodiamine affects the reaction [T-2 Toxin affects the localization of RELA protein]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in increased phosphorylation of RELA protein]]; evodiamine affects the reaction [T-2 Toxin affects the localization of RELA protein]; evodiamine inhibits the reaction [T-2 Toxin results in increased expression of RELA mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in increased phosphorylation of RELA protein]
2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein]]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 mRNA]; evodiamine inhibits the reaction [T-2 Toxin results in decreased expression of TJP1 protein]
Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]
Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]
Sirolimus results in increased expression of FOXO1 mRNA; Sirolimus results in increased expression of FOXO1 protein Sirolimus affects the localization of FOXO1 protein
Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] Sirolimus results in decreased expression of INS mRNA; Sirolimus results in decreased expression of INS protein
Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]]; Sirolimus inhibits the reaction [Benzo(a)pyrene results in decreased lipidation of MAP1LC3B protein]
Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of BECN1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of DCTN4 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of GPX1 mRNA]; Sirolimus affects the reaction [[MYD88 protein affects the susceptibility to Paraquat] which affects the expression of SOD1 mRNA]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of FIS1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of OPA1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of DNM1L mRNA]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in increased expression of FIS1 mRNA]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of BECN1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the expression of SQSTM1 protein]]; Sirolimus affects the reaction [Paraquat affects the reaction [MYD88 protein affects the lipidation of MAP1LC3B protein]]
Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat affects the expression of OPA1 protein]]; Sirolimus affects the reaction [MYD88 protein affects the reaction [Paraquat results in decreased expression of OPA1 mRNA]]
Thapsigargin results in increased expression of HSP90B1 protein PD 150606 inhibits the reaction [Thapsigargin results in increased cleavage of HSP90B1 protein] Thapsigargin results in decreased expression of HSP90B1 protein
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