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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:zinc coordination entity
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Accession:CHEBI:36566 term browser browse the term
Synonyms:related_synonym: zinc coordination compounds;   zinc coordination entities


show annotations for term's descendants           Sort by:
mancozeb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase affects activity
multiple interactions 		EXP mancozeb affects the activity of ACHE protein
[carbendazim co-treated with mancozeb] results in increased activity of ACHE protein 		CTD PMID:10641187 PMID:33217513 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Actg1 actin, gamma 1 increases expression ISO mancozeb results in increased expression of ACTG1 protein CTD PMID:21375462 NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951 		JBrowse link
G Actmap actin maturation protease decreases expression ISO mancozeb results in decreased expression of ACTMAP mRNA CTD PMID:33396126 NCBI chr 1:91,618,012...91,627,490
Ensembl chr 1:91,617,859...91,627,489 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin decreases expression ISO mancozeb results in decreased expression of ALB protein CTD PMID:21375462 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity
multiple interactions 		EXP
ISO 		mancozeb results in decreased activity of ALDH2 protein
[Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of ALDH2 mRNA; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of and results in decreased activity of ALDH2 protein 		CTD PMID:17010440 PMID:34830855 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity EXP mancozeb results in decreased activity of ALDH5A1 protein CTD PMID:17010440 NCBI chr17:40,560,373...40,586,711
Ensembl chr17:40,558,347...40,586,714 		JBrowse link
G Angptl1 angiopoietin-like 1 decreases expression ISO mancozeb results in decreased expression of ANGPTL1 mRNA CTD PMID:33396126 NCBI chr13:71,463,913...71,531,810
Ensembl chr13:71,511,727...71,531,818 		JBrowse link
G Anxa2 annexin A2 decreases expression ISO mancozeb results in decreased expression of ANXA2 protein CTD PMID:21375462 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
decreases activity 		ISO mancozeb inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; mancozeb inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]
mancozeb results in decreased expression of AR mRNA
mancozeb results in decreased activity of AR protein 		CTD PMID:23871939 PMID:33396126 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO mancozeb results in decreased expression of ATP1A2 mRNA CTD PMID:33396126 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:87,261,968...87,286,911 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		ISO mancozeb results in increased expression of BAX mRNA
mancozeb results in increased expression of BAX protein
[Sulfur co-treated with mancozeb co-treated with metrafenone] results in decreased expression of BAX mRNA; [Sulfur co-treated with mancozeb] results in decreased expression of BAX mRNA; lupeol inhibits the reaction [mancozeb results in increased expression of BAX mRNA] 		CTD PMID:27235710 PMID:35564597 PMID:35617905 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO
EXP 		mancozeb results in decreased expression of BCL2 mRNA
mancozeb results in decreased expression of BCL2 protein
[Sulfur co-treated with mancozeb co-treated with metrafenone] results in decreased expression of BCL2 mRNA; [Sulfur co-treated with mancozeb] results in decreased expression of BCL2 mRNA; lupeol inhibits the reaction [mancozeb results in decreased expression of BCL2 mRNA]
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein] 		CTD PMID:16005924 PMID:27235710 PMID:35564597 PMID:35617905 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO mancozeb results in increased expression of CAR3 protein CTD PMID:21375462 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
increases cleavage 		ISO mancozeb results in increased activity of CASP3 protein
mancozeb results in increased expression of CASP3 protein
Acetylcysteine inhibits the reaction [mancozeb results in increased cleavage of CASP3 protein] 		CTD PMID:22824503 PMID:30037311 PMID:35617905 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity ISO mancozeb results in increased activity of CASP7 protein CTD PMID:22824503 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases activity ISO mancozeb results in increased activity of CASP8 protein CTD PMID:22824503 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity
increases expression 		ISO mancozeb results in increased activity of CASP9 protein
mancozeb results in increased expression of CASP9 protein 		CTD PMID:22824503 PMID:35617905 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
decreases activity 		ISO
EXP 		Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; lupeol inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Quercetin inhibits the reaction [mancozeb results in decreased activity of CAT protein]
Colforsin inhibits the reaction [mancozeb results in decreased activity of CAT protein] 		CTD PMID:23024109 PMID:27235710 PMID:29283200 PMID:30037311 PMID:35617905 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccdc106 coiled-coil domain containing 106 decreases expression ISO mancozeb results in decreased expression of CCDC106 mRNA CTD PMID:33396126 NCBI chr 1:77,808,723...77,812,816
Ensembl chr 1:77,808,723...77,852,105 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression 		ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein
mancozeb results in increased expression of CCND1 protein 		CTD PMID:19883720 PMID:21375462 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cdc25c cell division cycle 25C increases phosphorylation ISO mancozeb results in increased phosphorylation of CDC25C protein CTD PMID:21375462 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO lupeol inhibits the reaction [mancozeb results in increased expression of CDKN1A mRNA] CTD PMID:27235710 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cfap126 cilia and flagella associated protein 126 decreases expression ISO mancozeb results in decreased expression of CFAP126 mRNA CTD PMID:33396126 NCBI chr13:86,059,142...86,075,034
Ensembl chr13:86,059,142...86,075,034 		JBrowse link
G Cldn16 claudin 16 decreases expression ISO mancozeb results in decreased expression of CLDN16 mRNA CTD PMID:33396126 NCBI chr11:87,795,106...87,814,396
Ensembl chr11:87,795,106...87,814,396 		JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO mancozeb results in decreased expression of CTF1 mRNA CTD PMID:33396126 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO mancozeb results in increased expression of CYCS protein CTD PMID:27016407 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
decreases expression 		EXP
ISO 		mancozeb results in decreased activity of CYP1A1 protein
mancozeb results in decreased expression of CYP1A1 protein 		CTD PMID:1946188 PMID:31096615 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression ISO mancozeb results in decreased expression of CYP2B6 protein CTD PMID:31096615 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO mancozeb results in decreased expression of CYP2E1 mRNA CTD PMID:31096615 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO mancozeb results in decreased expression of CYP3A4 mRNA; mancozeb results in decreased expression of CYP3A4 protein CTD PMID:31096615 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression EXP mancozeb results in increased expression of DDIT4 protein CTD PMID:24764117 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO mancozeb results in decreased expression of DNMT1 protein CTD PMID:36007320 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO mancozeb results in decreased expression of DNMT3A protein CTD PMID:36007320 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO mancozeb results in decreased expression of DUSP1 mRNA CTD PMID:36007320 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Efcab12 EF-hand calcium binding domain 12 decreases expression ISO mancozeb results in decreased expression of EFCAB12 mRNA CTD PMID:33396126 NCBI chr 4:150,541,983...150,563,973
Ensembl chr 4:150,541,982...150,563,286 		JBrowse link
G Efna1 ephrin A1 decreases expression ISO mancozeb results in decreased expression of EFNA1 mRNA CTD PMID:36007320 NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726 		JBrowse link
G Efna3 ephrin A3 decreases expression ISO mancozeb results in decreased expression of EFNA3 mRNA CTD PMID:36007320 NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation ISO mancozeb results in increased phosphorylation of ELK1 protein CTD PMID:21375462 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO mancozeb results in decreased expression of ESR1 mRNA CTD PMID:33396126 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO mancozeb results in decreased expression of ESR2 mRNA; mancozeb results in decreased expression of ESR2 protein CTD PMID:33396126 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO mancozeb results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO mancozeb results in decreased expression of FOS mRNA CTD PMID:36007320 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
decreases expression
increases expression 		ISO lupeol inhibits the reaction [mancozeb results in increased expression of GADD45A mRNA]
mancozeb results in decreased expression of GADD45A mRNA 		CTD PMID:27235710 PMID:36007320 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Glyatl3 glycine-N-acyltransferase-like 3 decreases expression ISO mancozeb results in decreased expression of GLYATL3 mRNA CTD PMID:33396126 NCBI chr 9:27,474,057...27,492,281
Ensembl chr 9:27,474,057...27,492,281 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 affects activity EXP mancozeb affects the activity of GOT1 protein CTD PMID:10641187 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity
multiple interactions 		EXP mancozeb affects the activity of GPT protein
[2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide co-treated with mancozeb] results in increased expression of GPT protein; Resveratrol inhibits the reaction [[2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide co-treated with mancozeb] results in increased expression of GPT protein] 		CTD PMID:10641187 PMID:37009748 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions 		ISO mancozeb results in decreased expression of GPX1 mRNA
Acetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA] 		CTD PMID:30037311 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in increased expression of H2AX protein CTD PMID:34830855 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hdac3 histone deacetylase 3 decreases activity ISO mancozeb results in decreased activity of HDAC3 protein CTD PMID:21251949 NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025 		JBrowse link
G Hdac6 histone deacetylase 6 decreases activity ISO mancozeb results in decreased activity of HDAC6 protein CTD PMID:21251949 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M increases expression ISO mancozeb results in increased expression of HNRNPM protein CTD PMID:21375462 NCBI chr 7:15,140,877...15,178,871
Ensembl chr 7:15,129,287...15,178,871 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO mancozeb results in increased expression of HSPA1B mRNA CTD PMID:36007320 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO mancozeb results in decreased expression of IFITM2 mRNA CTD PMID:33396126 NCBI chr 1:205,481,168...205,482,348 JBrowse link
G Ifng interferon gamma multiple interactions ISO mancozeb affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:15742816 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO mancozeb inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:16112155 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 affects expression ISO mancozeb affects the expression of IL2 protein CTD PMID:9012323 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression ISO mancozeb results in decreased expression of ITGB3 mRNA; mancozeb results in decreased expression of ITGB3 protein CTD PMID:33396126 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases activity EXP mancozeb results in increased activity of KCNQ2 protein CTD PMID:23542819 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor affects expression EXP mancozeb affects the expression of KISS1 mRNA CTD PMID:23660487 NCBI chr13:47,327,159...47,332,759
Ensembl chr13:47,327,004...47,332,906 		JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 increases expression ISO mancozeb results in increased expression of LTB4R2 mRNA CTD PMID:33396126 NCBI chr15:33,228,634...33,230,453
Ensembl chr15:33,228,634...33,230,453 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases expression ISO mancozeb results in increased expression of MAP3K5 mRNA CTD PMID:36007320 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 increases expression ISO mancozeb results in increased expression of MAP3K6 mRNA CTD PMID:36007320 NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mancozeb results in increased activity of MAPK1 protein]; mancozeb results in increased localization of and results in increased activity of MAPK1 protein CTD PMID:21375462 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mancozeb results in increased activity of MAPK3 protein]; mancozeb results in increased localization of and results in increased activity of MAPK3 protein CTD PMID:21375462 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression 		ISO lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] CTD PMID:27235710 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b decreases expression ISO mancozeb results in decreased expression of CYTB mRNA CTD PMID:35617905 NCBI chr MT:14,136...15,278
Ensembl chr MT:14,124...15,266 		JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO mancozeb results in decreased expression of ND3 mRNA CTD PMID:35617905 NCBI chr MT:9,451...9,798
Ensembl chr MT:9,436...9,783 		JBrowse link
G Mt-nd4l mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L decreases expression ISO mancozeb results in decreased expression of ND4L mRNA CTD PMID:35617905 NCBI chr MT:9,870...10,166
Ensembl chr MT:9,855...10,151 		JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 decreases expression ISO mancozeb results in decreased expression of ND6 mRNA CTD PMID:35617905 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO mancozeb results in decreased expression of MUC1 mRNA; mancozeb results in decreased expression of MUC1 protein CTD PMID:33396126 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
increases expression 		ISO
EXP 		[alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein
mancozeb results in decreased expression of MYC mRNA
mancozeb results in increased expression of MYC protein
mancozeb results in decreased expression of MYC protein
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of MYC protein] 		CTD PMID:16005924 PMID:19883720 PMID:36007320 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nhlrc1 NHL repeat containing E3 ubiquitin protein ligase 1 decreases expression ISO mancozeb results in decreased expression of NHLRC1 mRNA CTD PMID:33396126 NCBI chr17:17,880,570...17,883,411
Ensembl chr17:17,880,365...17,883,620 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions 		ISO mancozeb results in increased expression of NOS2 mRNA
Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOS2 mRNA] 		CTD PMID:30037311 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression 		ISO Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOX4 mRNA] CTD PMID:30037311 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO mancozeb results in decreased expression of NR4A1 mRNA CTD PMID:36007320 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO mancozeb results in increased activity of ODC1 protein CTD PMID:1733566 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions
decreases expression 		ISO lupeol inhibits the reaction [mancozeb results in decreased expression of OGG1 mRNA] CTD PMID:27235710 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Or1s2 olfactory receptor family 1 subfamily S member 2 increases expression ISO mancozeb results in increased expression of OR1S1 mRNA CTD PMID:33396126 NCBI chr 1:220,338,536...220,339,483
Ensembl chr 1:220,338,530...220,339,483 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO mancozeb results in decreased activity of and results in increased oxidation of PARK7 protein CTD PMID:36842454 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Pcdhb20 protocadherin beta 20 decreases expression ISO mancozeb results in decreased expression of PCDHB14 mRNA CTD PMID:33396126 NCBI chr18:29,485,888...29,489,282
Ensembl chr18:29,454,999...29,489,427 		JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO mancozeb results in increased expression of PRDX2 protein CTD PMID:21375462 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Prl prolactin multiple interactions
increases expression 		ISO [mancozeb co-treated with imidacloprid] results in increased expression of PRL protein
mancozeb results in increased expression of PRL mRNA 		CTD PMID:24530807 PMID:33396126 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Ptges prostaglandin E synthase increases expression
decreases expression
multiple interactions 		ISO mancozeb results in increased expression of PTGES mRNA
mancozeb results in decreased expression of PTGES protein
lupeol inhibits the reaction [mancozeb results in increased expression of PTGES mRNA] 		CTD PMID:27235710 PMID:32446389 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptges3 prostaglandin E synthase 3 decreases expression ISO mancozeb results in decreased expression of PTGES3 mRNA CTD PMID:32446389 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO mancozeb results in increased expression of PTGS2 protein CTD PMID:21375462 PMID:32446389 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Pvalb parvalbumin increases expression ISO mancozeb results in increased expression of PVALB protein CTD PMID:21375462 NCBI chr 7:111,653,820...111,668,469
Ensembl chr 7:111,653,111...111,668,446 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
affects localization
multiple interactions 		ISO mancozeb results in increased phosphorylation of RELA protein
mancozeb affects the localization of RELA protein
Acetylcysteine inhibits the reaction [mancozeb affects the localization of RELA protein]; lupeol inhibits the reaction [mancozeb affects the localization of RELA protein]; mancozeb inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein] 		CTD PMID:16112155 PMID:21375462 PMID:27235710 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO mancozeb results in increased expression of S100A6 protein CTD PMID:21375462 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO mancozeb results in increased expression of S100A9 protein CTD PMID:21375462 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Scx scleraxis bHLH transcription factor decreases expression ISO mancozeb results in decreased expression of SCX mRNA CTD PMID:33396126 NCBI chr 7:110,056,897...110,059,283
Ensembl chr 7:110,054,601...110,061,438 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C decreases expression ISO mancozeb results in decreased expression of SDHC mRNA CTD PMID:35617905 NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044 		JBrowse link
G Septin11 septin 11 increases expression ISO mancozeb results in increased expression of SEPTIN11 mRNA CTD PMID:33396126 NCBI chr14:15,119,760...15,275,222
Ensembl chr14:15,128,951...15,275,200 		JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO mancozeb results in decreased expression of SERPINF1 mRNA CTD PMID:33396126 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898 		JBrowse link
G Sirt1 sirtuin 1 decreases activity ISO mancozeb results in decreased activity of SIRT1 protein CTD PMID:21251949 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sirt2 sirtuin 2 decreases activity ISO mancozeb results in decreased activity of SIRT2 protein CTD PMID:21251949 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499 		JBrowse link
G Sirt3 sirtuin 3 decreases activity ISO mancozeb results in decreased activity of SIRT3 protein CTD PMID:21251949 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO mancozeb results in decreased expression of SLC14A1 mRNA CTD PMID:33396126 NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO mancozeb inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine] CTD PMID:27979590 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691 		JBrowse link
G Snord82 small nucleolar RNA, C/D box 82 increases expression ISO mancozeb results in increased expression of SNORD82 mRNA CTD PMID:33396126 NCBI chr 9:94,452,486...94,452,557
Ensembl chr 9:94,452,486...94,452,557 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
decreases activity 		ISO mancozeb results in decreased expression of SOD1 protein
mancozeb results in decreased activity of SOD1 protein 		CTD PMID:21375462 PMID:35617905 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 decreases expression ISO mancozeb results in decreased expression of SULT2B1 mRNA CTD PMID:33396126 NCBI chr 1:105,336,614...105,397,744
Ensembl chr 1:105,336,614...105,397,744 		JBrowse link
G Tek TEK receptor tyrosine kinase increases activity ISO mancozeb results in increased activity of TEK protein CTD PMID:21251949 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression ISO mancozeb results in decreased expression of TGFB1I1 mRNA CTD PMID:33396126 NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO mancozeb affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein]
mancozeb inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; mancozeb inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; mancozeb inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein] 		CTD PMID:15742816 PMID:15893782 PMID:16112155 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
multiple interactions 		ISO mancozeb results in decreased expression of TRP53 mRNA; mancozeb results in decreased expression of TRP53 protein
mancozeb results in increased expression of TP53 mRNA
lupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA] 		CTD PMID:22369882 PMID:27235710 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO mancozeb results in increased expression of TPI1 protein CTD PMID:21375462 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413 		JBrowse link
G Tpo thyroid peroxidase decreases activity EXP mancozeb results in decreased activity of TPO protein CTD PMID:9418944 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of TSHB protein CTD PMID:24530807 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression
multiple interactions 		ISO mancozeb results in decreased expression of XRCC1 mRNA
lupeol inhibits the reaction [mancozeb results in decreased expression of XRCC1 mRNA] 		CTD PMID:27235710 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Zfp358 zinc finger protein 358 decreases expression ISO mancozeb results in decreased expression of ZNF358 mRNA CTD PMID:33396126 NCBI chr12:6,350,266...6,354,359
Ensembl chr12:6,350,067...6,354,897 		JBrowse link
metiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCB1 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCB1 protein CTD PMID:32800223 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC1 mRNA CTD PMID:32800223 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCC2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCC2 mRNA CTD PMID:32800223 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of ABCG2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of ABCG2 protein CTD PMID:32800223 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BAX protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BAX protein CTD PMID:32800223 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of BBC3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BBC3 mRNA CTD PMID:32800223 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of BCL2 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of BCL2 protein CTD PMID:32800223 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of BIRC2 mRNA CTD PMID:32800223 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of CASP3 protein; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CASP3 protein CTD PMID:32800223 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CASP8 protein CTD PMID:32800223 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of CYCS mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of CYCS mRNA CTD PMID:32800223 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of GSTM1 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of GSTM1 mRNA CTD PMID:32800223 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Hdac3 histone deacetylase 3 decreases activity ISO polymarcine results in decreased activity of HDAC3 protein CTD PMID:21251949 NCBI chr18:30,021,847...30,041,061
Ensembl chr18:30,021,941...30,041,025 		JBrowse link
G Hdac6 histone deacetylase 6 decreases activity ISO polymarcine results in decreased activity of HDAC6 protein CTD PMID:21251949 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Mvp major vault protein multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of MVP mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in increased expression of MVP mRNA CTD PMID:32800223 NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:191,025,268...191,052,873 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of PMAIP1 mRNA CTD PMID:32800223 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Sirt1 sirtuin 1 decreases activity ISO polymarcine results in decreased activity of SIRT1 protein CTD PMID:21251949 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sirt2 sirtuin 2 decreases activity ISO polymarcine results in decreased activity of SIRT2 protein CTD PMID:21251949 NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499 		JBrowse link
G Sirt3 sirtuin 3 decreases activity ISO polymarcine results in decreased activity of SIRT3 protein CTD PMID:21251949 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO polymarcine inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine] CTD PMID:27979590 NCBI chr16:18,580,705...18,590,692
Ensembl chr16:18,580,705...18,590,691 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNF mRNA CTD PMID:32800223 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TNFRSF10A mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TNFRSF10A mRNA CTD PMID:32800223 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Cisplatin] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in decreased expression of TP53 mRNA; [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Temozolomide] which results in decreased expression of TP53 mRNA CTD PMID:32800223 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO [[Chlorpyrifos co-treated with decamethrin co-treated with polymarcine co-treated with Glyphosate] results in decreased susceptibility to Fluorouracil] which results in increased expression of XIAP mRNA CTD PMID:32800223 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
propineb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase decreases activity ISO propineb results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
zinc protoporphyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]]; zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]]
zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] 		CTD PMID:20052772 PMID:20861358 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Agt angiotensinogen multiple interactions ISO [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:20523338 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of AKT1 protein] CTD PMID:19387321 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alad aminolevulinate dehydratase affects abundance ISO ALAD gene SNP affects the abundance of zinc protoporphyrin CTD PMID:25963508 NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041 		JBrowse link
G Alb albumin multiple interactions ISO ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; ALB protein inhibits the reaction [zinc protoporphyrin results in increased expression of HMOX1 protein]
zinc protoporphyrin inhibits the reaction [ALB protein results in increased expression of HMOX1 protein]; zinc protoporphyrin promotes the reaction [ALB protein results in increased expression of TIMP1 protein] 		CTD PMID:19376148 PMID:21163135 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of ALMS1 mRNA CTD PMID:22839698 NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471 		JBrowse link
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of AP2A1 mRNA CTD PMID:22839698 NCBI chr 1:104,520,789...104,550,655
Ensembl chr 1:104,520,792...104,550,655 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of AP3D1 mRNA CTD PMID:22839698 NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:9,620,968...9,656,342 		JBrowse link
G Asf1a anti-silencing function 1A histone chaperone multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of ASF1A mRNA CTD PMID:22839698 NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions EXP zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in decreased expression of NFE2L2 mRNA]]; zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]; zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in increased expression of PTGS2 mRNA]]; zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in increased expression of PTGS2 protein]] CTD PMID:38573338 NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; zinc protoporphyrin inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in increased expression of BAX protein]]
zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in increased expression of BAX mRNA]]
zinc protoporphyrin inhibits the reaction [Cisplatin results in increased expression of BAX protein] 		CTD PMID:22763982 PMID:27523796 PMID:27815112 PMID:32621855 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; zinc protoporphyrin inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]
zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]] 		CTD PMID:22763982 PMID:27523796 PMID:32621855 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression 		EXP
ISO 		zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of BCL2L1 protein]
zinc protoporphyrin results in increased expression of BCL2L1 protein 		CTD PMID:20357190 PMID:27829220 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO zinc protoporphyrin results in increased expression of BCL2L11 protein CTD PMID:27829220 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions EXP zinc protoporphyrin inhibits the reaction [15-deoxyprostaglandin J2 results in decreased expression of BGLAP mRNA]; zinc protoporphyrin inhibits the reaction [Hemin results in decreased expression of BGLAP mRNA] CTD PMID:20020468 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein] CTD PMID:18508827 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP zinc protoporphyrin inhibits the reaction [monophosphoryl lipid A results in increased expression of CALCA mRNA] CTD PMID:11738242 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of CAND1 mRNA CTD PMID:22839698 NCBI chr 7:56,566,765...56,604,653
Ensembl chr 7:56,551,394...56,604,655 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]] CTD PMID:36858639 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
decreases activity 		ISO
EXP 		zinc protoporphyrin inhibits the reaction [[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Resveratrol inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]]; zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased activity of CASP3 protein]]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP3 protein]
zinc protoporphyrin results in increased cleavage of CASP3 protein
zinc protoporphyrin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP3 protein]]; zinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP3 protein]; zinc protoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [rutecarpine inhibits the reaction [tert-Butylhydroperoxide results in increased activity of CASP3 protein]]; zinc protoporphyrin promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein]; zinc protoporphyrin promotes the reaction [quinocetone results in increased activity of CASP3 protein]
zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of CASP3 protein]; zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in increased expression of CASP3 mRNA]]; zinc protoporphyrin promotes the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased cleavage of CASP3 protein]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased cleavage of CASP3 protein]
zinc protoporphyrin results in decreased activity of CASP3 protein 		CTD PMID:16051694 PMID:17928392 PMID:20357190 PMID:21295052 PMID:22763982 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO zinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP8 protein] CTD PMID:16051694 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased activity of CASP9 protein]]; zinc protoporphyrin promotes the reaction [quinocetone results in increased activity of CASP9 protein]
zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein]]; zinc protoporphyrin promotes the reaction [T-2 Toxin results in increased activity of CASP9 protein] 		CTD PMID:27375190 PMID:29432840 PMID:30261164 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions EXP
ISO 		zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in decreased expression of CAT protein]]
zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]] 		CTD PMID:32621855 PMID:35691465 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of CCDC6 mRNA CTD PMID:22839698 NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP
ISO 		zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of CCL2 protein]; zinc protoporphyrin promotes the reaction [Indomethacin results in increased expression of CCL2 mRNA]
zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]] 		CTD PMID:20357190 PMID:23892052 PMID:35691465 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CCR7 mRNA] CTD PMID:33049506 NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] CTD PMID:33049506 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 mRNA] CTD PMID:33049506 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd83 CD83 molecule multiple interactions ISO zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CD83 mRNA] CTD PMID:33049506 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 mRNA] CTD PMID:33049506 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cdk13 cyclin-dependent kinase 13 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of CDK13 mRNA CTD PMID:22839698 NCBI chr17:51,945,975...52,040,218
Ensembl chr17:51,946,701...52,037,257 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CDKN1A protein] CTD PMID:18508827 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Chd7 chromodomain helicase DNA binding protein 7 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of CHD7 mRNA CTD PMID:22839698 NCBI chr 5:26,609,245...26,792,736
Ensembl chr 5:26,609,407...26,792,734 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of CMBL mRNA CTD PMID:22839698 NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP zinc protoporphyrin results in increased expression of CXCL1 mRNA CTD PMID:25780291 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]] CTD PMID:20861358 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression EXP zinc protoporphyrin results in increased expression of CXCL2 mRNA CTD PMID:25780291 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A1 protein CTD PMID:26747958 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A2 protein CTD PMID:26747958 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2B1 protein CTD PMID:26747958 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP
ISO 		[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA; [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 protein; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]
zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]]; zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]] 		CTD PMID:19325051 PMID:26747958 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Dcun1d1 defective in cullin neddylation 1 domain containing 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of DCUN1D1 mRNA CTD PMID:22839698 NCBI chr 2:120,649,445...120,700,879
Ensembl chr 2:120,649,445...120,700,870 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP zinc protoporphyrin promotes the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of DDIT3 protein]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of DDIT3 protein] CTD PMID:26747958 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dhx29 DExH-box helicase 29 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of DHX29 mRNA CTD PMID:22839698 NCBI chr 2:46,293,901...46,344,652
Ensembl chr 2:46,293,677...46,344,948 		JBrowse link
G Dusp10 dual specificity phosphatase 10 multiple interactions ISO zinc protoporphyrin inhibits the reaction [andrographolide results in increased expression of DUSP10 mRNA]; zinc protoporphyrin inhibits the reaction [andrographolide results in increased expression of DUSP10 protein] CTD PMID:29165873 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP zinc protoporphyrin promotes the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased phosphorylation of EIF2AK3 protein]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26747958 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eml4 EMAP like 4 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of EML4 mRNA CTD PMID:22839698 NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [F2 protein results in increased expression of PTGS2 protein]]; zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [F2 protein results in increased secretion of Dinoprostone]] CTD PMID:26385185 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Faslg Fas ligand multiple interactions ISO zinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP3 protein]; zinc protoporphyrin inhibits the reaction [FASLG protein results in increased activity of CASP8 protein]; zinc protoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of CASP3 protein] CTD PMID:16051694 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fbxw12 F-box and WD repeat domain containing 12 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of FBXW12 mRNA CTD PMID:22839698 NCBI chr 8:118,660,777...118,680,565
Ensembl chr 8:118,660,605...118,680,572 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of FGFR1 mRNA CTD PMID:22839698 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Diazoxide inhibits the reaction [Oxygen deficiency results in increased expression of FLT1 protein]] CTD PMID:25371888 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO zinc protoporphyrin results in increased expression of FOS mRNA CTD PMID:10381381 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fut4 fucosyltransferase 4 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of FUT4 mRNA CTD PMID:22839698 NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:19,868,079...19,872,436 		JBrowse link
G Glul glutamate-ammonia ligase multiple interactions EXP zinc protoporphyrin inhibits the reaction [Resveratrol inhibits the reaction [Ammonia results in decreased activity of GLUL protein]]; zinc protoporphyrin inhibits the reaction [Resveratrol results in increased activity of GLUL protein] CTD PMID:26318273 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520 		JBrowse link
G Gpr132 G protein-coupled receptor 132 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of GPR132 mRNA CTD PMID:22839698 NCBI chr 6:137,745,142...137,763,037
Ensembl chr 6:137,745,241...137,763,157 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX1 protein] CTD PMID:36696656 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]
zinc protoporphyrin inhibits the reaction [Cadmium results in decreased expression of GPX4 protein] 		CTD PMID:36696656 PMID:39025289 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gsdmd gasdermin D multiple interactions ISO zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]] CTD PMID:36858639 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 multiple interactions EXP zinc protoporphyrin inhibits the reaction [5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]]; zinc protoporphyrin inhibits the reaction [BAY 58-2667 inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]] CTD PMID:19466990 NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP zinc protoporphyrin inhibits the reaction [5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]]; zinc protoporphyrin inhibits the reaction [BAY 58-2667 binds to GUCY1B1 protein]; zinc protoporphyrin inhibits the reaction [BAY 58-2667 inhibits the reaction [Heme deficiency results in decreased activity of [GUCY1A1 protein binds to GUCY1B1 protein]]] CTD PMID:19466990 NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987 		JBrowse link
G Haus2 HAUS augmin like complex subunit 2 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of HAUS2 mRNA CTD PMID:22839698 NCBI chr 3:128,006,894...128,019,730
Ensembl chr 3:128,006,932...128,019,729 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP zinc protoporphyrin inhibits the reaction [Cadmium results in increased expression of HAVCR1 protein] CTD PMID:39025289 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hfe homeostatic iron regulator affects abundance ISO HFE gene polymorphism affects the abundance of zinc protoporphyrin CTD PMID:25963508 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO zinc protoporphyrin inhibits the reaction [HIF1A protein results in increased activity of SOD2 protein] CTD PMID:17066447 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP
ISO 		zinc protoporphyrin promotes the reaction [lead acetate results in increased expression of HMGB1 mRNA]
zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]] 		CTD PMID:29447957 PMID:30261164 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
increases expression
affects expression
decreases activity 		ISO
EXP 		[zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] which results in increased susceptibility to 2-butenal; [zinc protoporphyrin results in decreased activity of HMOX1 protein] which results in increased susceptibility to Arsenic Trioxide; [zinc protoporphyrin results in decreased activity of HMOX1] which results in decreased susceptibility to peoniflorin; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron]; zinc protoporphyrin inhibits the reaction [[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in decreased abundance of Glutathione]]; zinc protoporphyrin inhibits the reaction [[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in increased abundance of Malondialdehyde]]; zinc protoporphyrin inhibits the reaction [[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased susceptibility to Ethanol]; zinc protoporphyrin inhibits the reaction [ALB protein results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Cilostazol results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [Cilostazol results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased activity of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]; zinc protoporphyrin inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; zinc protoporphyrin results in decreased expression of and results in decreased activity of HMOX1 protein; zinc protoporphyrin results in increased expression of and results in decreased activity of HMOX1 protein
zinc protoporphyrin results in decreased expression of HMOX1 mRNA; zinc protoporphyrin results in decreased expression of HMOX1 protein
zinc protoporphyrin results in increased expression of HMOX1 protein
zinc protoporphyrin affects the expression of HMOX1 mRNA; zinc protoporphyrin affects the expression of HMOX1 protein
zinc protoporphyrin results in decreased activity of HMOX1; zinc protoporphyrin results in decreased activity of HMOX1 protein
zinc protoporphyrin results in increased expression of HMOX1 mRNA; zinc protoporphyrin results in increased expression of HMOX1 protein
[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of HMOX1 mRNA; [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with zinc protoporphyrin] results in increased expression of HMOX1 mRNA; [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Resveratrol results in increased abundance of Glutathione]; [zinc protoporphyrin results in decreased activity of HMOX1 protein] which results in decreased susceptibility to Resveratrol; Hemin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA]]; Hemin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [Glucose results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Hemin promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA]]; zinc protoporphyrin inhibits the reaction [Hemin promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; zinc protoporphyrin inhibits the reaction [lead acetate results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [perflexane promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of and results in increased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Propofol promotes the reaction [Glucose results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Sildenafil Citrate results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [Sildenafil Citrate results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Tadalafil promotes the reaction [Cisplatin results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of HMOX1 protein]
[zinc protoporphyrin co-treated with Hemin] results in increased expression of HMOX1 mRNA; [zinc protoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; ALB protein inhibits the reaction [zinc protoporphyrin results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA]]; zinc protoporphyrin inhibits the reaction [8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone] results in increased expression of HMOX1 mRNA]; zinc protoporphyrin inhibits the reaction [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] promotes the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein results in increased abundance of Superoxides]; zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Resveratrol inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of HMOX1 protein]] 		CTD PMID:7524564 PMID:12352873 PMID:14649057 PMID:15602829 PMID:16462769 More... NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hmox2 heme oxygenase 2 decreases activity
decreases expression 		ISO
EXP 		zinc protoporphyrin results in decreased activity of HMOX2 protein
zinc protoporphyrin results in decreased expression of HMOX2 protein 		CTD PMID:21448202 PMID:25824035 NCBI chr10:11,303,512...11,337,640
Ensembl chr10:11,303,512...11,318,800 		JBrowse link
G Hp1bp3 heterochromatin protein 1, binding protein 3 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of HP1BP3 mRNA CTD PMID:22839698 NCBI chr 5:155,719,109...155,746,329
Ensembl chr 5:155,719,115...155,746,325 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased expression of HSD11B1 mRNA]] CTD PMID:27523796 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]
zinc protoporphyrin promotes the reaction [Indomethacin results in increased expression of ICAM1 mRNA]
zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] 		CTD PMID:19608869 PMID:23892052 PMID:33049506 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]] CTD PMID:20861358 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression 		EXP zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased expression of HMOX1 protein]
zinc protoporphyrin results in increased expression of IFNG mRNA 		CTD PMID:21295052 PMID:25780291 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of IL10 mRNA]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of IL10 protein]; zinc protoporphyrin inhibits the reaction [perflexane inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of IL10 protein]] CTD PMID:20056245 PMID:20360627 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO zinc protoporphyrin promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]] CTD PMID:33049506 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]]; zinc protoporphyrin inhibits the reaction [Hemin results in decreased susceptibility to IL18 protein] CTD PMID:18215737 PMID:36858639 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO
EXP 		zinc protoporphyrin inhibits the reaction [Cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL1B protein]]
zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]]; zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]
zinc protoporphyrin results in increased expression of IL1B mRNA
zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased expression of HMOX1 protein]; zinc protoporphyrin promotes the reaction [Indomethacin results in increased expression of IL1B mRNA] 		CTD PMID:20131233 PMID:21295052 PMID:23892052 PMID:25780291 PMID:27523796 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL23A mRNA]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL23A protein]] CTD PMID:33049506 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression 		ISO
EXP 		zinc protoporphyrin inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of IL6 protein]]
zinc protoporphyrin results in increased expression of IL6 mRNA
zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]] 		CTD PMID:19608869 PMID:20131233 PMID:21963524 PMID:25780291 PMID:27523796 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D decreases expression EXP zinc protoporphyrin results in decreased expression of INPP5D protein CTD PMID:25780291 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions EXP zinc protoporphyrin promotes the reaction [IRAK1 protein binds to MYD88 protein] CTD PMID:25780291 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 decreases expression EXP zinc protoporphyrin results in decreased expression of IRAK3 protein CTD PMID:25780291 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO zinc protoporphyrin results in increased expression of ITGAM protein CTD PMID:22118543 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO zinc protoporphyrin promotes the reaction [arsenic trioxide results in increased expression of JUN protein]
zinc protoporphyrin results in increased expression of JUN protein 		CTD PMID:27829220 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of KCNAB1 mRNA CTD PMID:22839698 NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:151,446,947...151,913,636 		JBrowse link
G Kctd20 potassium channel tetramerization domain containing 20 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of KCTD20 mRNA CTD PMID:22839698 NCBI chr20:7,017,480...7,034,440
Ensembl chr20:7,017,502...7,034,441 		JBrowse link
G Kidins220 kinase D-interacting substrate 220 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of KIDINS220 mRNA CTD PMID:22839698 NCBI chr 6:47,346,790...47,435,599
Ensembl chr 6:47,346,832...47,431,865 		JBrowse link
G Kitlg KIT ligand multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of KITLG mRNA CTD PMID:22839698 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of KRAS mRNA CTD PMID:22839698 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Larp1b La ribonucleoprotein 1B multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of LARP1B mRNA CTD PMID:22839698 NCBI chr 2:125,860,935...125,897,189
Ensembl chr 2:125,863,997...125,897,189 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP zinc protoporphyrin inhibits the reaction [Cadmium results in increased expression of LCN2 protein] CTD PMID:39025289 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of LDHA protein]] CTD PMID:36858639 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Lnx1 ligand of numb-protein X 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of LNX1 mRNA CTD PMID:22839698 NCBI chr14:33,868,517...33,971,217
Ensembl chr14:33,868,571...33,971,217 		JBrowse link
G Lyrm7 LYR motif containing 7 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of LYRM7 mRNA CTD PMID:22839698 NCBI chr10:39,465,019...39,483,973
Ensembl chr10:39,465,036...39,484,240 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of MACF1 mRNA CTD PMID:22839698 NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]]
zinc protoporphyrin results in increased phosphorylation of MAPK1 protein
zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; zinc protoporphyrin promotes the reaction [lipoteichoic acid results in increased phosphorylation of MAPK1 protein]; zinc protoporphyrin promotes the reaction [Peptidoglycan results in increased phosphorylation of MAPK1 protein] 		CTD PMID:19376148 PMID:20523338 PMID:27523796 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		ISO [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]]
zinc protoporphyrin results in increased phosphorylation of MAPK3 protein
zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; zinc protoporphyrin promotes the reaction [lipoteichoic acid results in increased phosphorylation of MAPK3 protein]; zinc protoporphyrin promotes the reaction [Peptidoglycan results in increased phosphorylation of MAPK3 protein] 		CTD PMID:19376148 PMID:20523338 PMID:27523796 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mark2 microtubule affinity regulating kinase 2 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of MARK2 mRNA CTD PMID:22839698 NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:213,890,213...213,955,149 		JBrowse link
G Mfn1 mitofusin 1 multiple interactions EXP Hemin inhibits the reaction [zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in decreased expression of MFN1 mRNA]]; Hemin inhibits the reaction [zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in decreased expression of MFN1 protein]]; zinc protoporphyrin inhibits the reaction [Hemin inhibits the reaction [Lipopolysaccharides results in decreased expression of MFN1 mRNA]]; zinc protoporphyrin inhibits the reaction [Hemin inhibits the reaction [Lipopolysaccharides results in decreased expression of MFN1 protein]]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in decreased expression of MFN1 mRNA]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in decreased expression of MFN1 protein] CTD PMID:27830717 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of MLLT3 mRNA CTD PMID:22839698 NCBI chr 5:107,305,008...107,561,352
Ensembl chr 5:107,284,766...107,561,352 		JBrowse link
G Mmp2 matrix metallopeptidase 2 affects expression
multiple interactions 		EXP
ISO 		zinc protoporphyrin affects the expression of MMP2
zinc protoporphyrin inhibits the reaction [fisetin results in decreased expression of MMP2 mRNA]; zinc protoporphyrin inhibits the reaction [fisetin results in decreased expression of MMP2 protein] 		CTD PMID:23704825 PMID:30076913 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO zinc protoporphyrin promotes the reaction [arsenic trioxide results in increased expression of MMP9 protein]
zinc protoporphyrin inhibits the reaction [fisetin results in decreased expression of MMP9 mRNA]; zinc protoporphyrin inhibits the reaction [fisetin results in decreased expression of MMP9 protein] 		CTD PMID:27829220 PMID:30076913 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP zinc protoporphyrin inhibits the reaction [perflexane inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of MPO protein]]; zinc protoporphyrin promotes the reaction [Indomethacin results in increased activity of MPO protein]; zinc protoporphyrin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:17292349 PMID:20360627 PMID:23892052 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP zinc protoporphyrin promotes the reaction [IRAK1 protein binds to MYD88 protein]; zinc protoporphyrin promotes the reaction [TLR2 protein binds to MYD88 protein]; zinc protoporphyrin promotes the reaction [TLR4 protein binds to MYD88 protein]; zinc protoporphyrin promotes the reaction [TRAF6 protein binds to MYD88 protein] CTD PMID:25780291 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]] CTD PMID:19608869 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects expression 		EXP zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in decreased expression of NFE2L2 mRNA]]; zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]]; zinc protoporphyrin inhibits the reaction [Hemin results in increased expression of NFE2L2 protein]
zinc protoporphyrin affects the expression of NFE2L2 mRNA; zinc protoporphyrin affects the expression of NFE2L2 protein 		CTD PMID:23704825 PMID:25824035 PMID:38573338 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]] CTD PMID:21925249 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO zinc protoporphyrin inhibits the reaction [cilostazol results in increased expression of NFKBIA protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of NFKBIA protein]
zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]] 		CTD PMID:20131233 PMID:21925249 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP [Sildenafil Citrate co-treated with zinc protoporphyrin] results in increased expression of NOS1 mRNA CTD PMID:17627722 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP 		[zinc protoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; ALB protein inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; lactacystin inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; pyrazolanthrone inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; pyrazolanthrone inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; pyrazolanthrone inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]; zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of NOS2 mRNA; [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of NOS2 protein; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of NOS2 protein]; zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in increased expression of NOS2 mRNA]]; zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased expression of NOS2 mRNA]]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of NOS2 mRNA]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of NOS2 protein] 		CTD PMID:19376148 PMID:20357190 PMID:21925249 PMID:26460608 PMID:26747958 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of PDE4DIP mRNA CTD PMID:22839698 NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869 		JBrowse link
G Pgf placental growth factor multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of PGF mRNA CTD PMID:22839698 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Polr3k RNA polymerase III subunit K multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of POLR3K mRNA CTD PMID:22839698 NCBI chr 3:189,360,349...189,364,546
Ensembl chr 3:189,360,171...189,366,697 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO zinc protoporphyrin inhibits the reaction [cilostazol results in increased activity of PPARG protein]; zinc protoporphyrin inhibits the reaction [rosiglitazone results in increased activity of PPARG protein] CTD PMID:21660147 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of PPIL1 mRNA CTD PMID:22839698 NCBI chr20:7,303,919...7,323,962
Ensembl chr20:7,303,922...7,318,781 		JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of PRDX2 mRNA CTD PMID:22839698 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Prr11 proline rich 11 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of PRR11 mRNA CTD PMID:22839698 NCBI chr10:72,396,127...72,440,643
Ensembl chr10:72,398,667...72,418,275 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [F2 protein results in increased expression of PTGS2 protein]]; zinc protoporphyrin promotes the reaction [Arsenic Trioxide results in increased expression of PTGS2]
zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in increased expression of PTGS2 mRNA]]; zinc protoporphyrin affects the reaction [BACH1 protein affects the reaction [Doxorubicin results in increased expression of PTGS2 protein]]; zinc protoporphyrin inhibits the reaction [Cadmium results in increased expression of PTGS2 protein]
zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]; zinc protoporphyrin promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] 		CTD PMID:23649692 PMID:24003391 PMID:26385185 PMID:30261164 PMID:38573338 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of PTPN12 mRNA CTD PMID:22839698 NCBI chr 4:14,913,071...14,985,084
Ensembl chr 4:14,913,218...14,985,284 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of PTPRO mRNA CTD PMID:22839698 NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903 		JBrowse link
G Rap2c RAP2C, member of RAS oncogene family multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of RAP2C mRNA CTD PMID:22839698 NCBI chr  X:135,388,881...135,401,998
Ensembl chr  X:135,388,882...135,401,998 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]]; zinc protoporphyrin inhibits the reaction [Curcumin inhibits the reaction [quinocetone results in increased expression of RELA mRNA]]; zinc protoporphyrin promotes the reaction [quinocetone results in increased expression of RELA mRNA]
zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of RELA protein]
zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased localization of and results in increased activity of RELA protein]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein modified form]] 		CTD PMID:19608869 PMID:20131233 PMID:20357190 PMID:21925249 PMID:27375190 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rgcc regulator of cell cycle multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of RGCC mRNA CTD PMID:22839698 NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408 		JBrowse link
G Scaf11 SR-related CTD-associated factor 11 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SCAF11 mRNA CTD PMID:22839698 NCBI chr 7:129,450,872...129,503,280
Ensembl chr 7:129,417,955...129,503,280 		JBrowse link
G Scamp1 secretory carrier membrane protein 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SCAMP1 mRNA CTD PMID:22839698 NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742 		JBrowse link
G Sec23b Sec23 homolog B, COPII coat complex component multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SEC23B mRNA CTD PMID:22839698 NCBI chr 3:152,392,340...152,434,813
Ensembl chr 3:152,392,308...152,434,800 		JBrowse link
G Sel1l SEL1L adaptor subunit of SYVN1 ubiquitin ligase multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SEL1L mRNA CTD PMID:22839698 NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein] CTD PMID:34520103 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SLC22A3 mRNA CTD PMID:22839698 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc35e1 solute carrier family 35, member E1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SLC35E1 mRNA CTD PMID:22839698 NCBI chr16:17,384,980...17,398,227
Ensembl chr16:17,385,030...17,397,310 		JBrowse link
G Smcr8 SMCR8-C9orf72 complex subunit multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SMCR8 mRNA CTD PMID:22839698 NCBI chr10:45,957,146...45,968,388
Ensembl chr10:45,957,104...45,968,389 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SOD2 mRNA; zinc protoporphyrin inhibits the reaction [HIF1A protein results in increased activity of SOD2 protein] CTD PMID:17066447 PMID:22839698 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of SPTBN1 mRNA CTD PMID:22839698 NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]] CTD PMID:19608869 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Ssbp3 single stranded DNA binding protein 3 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of SSBP3 mRNA CTD PMID:22839698 NCBI chr 5:126,920,145...127,057,968
Ensembl chr 5:126,919,120...127,056,799 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of ST3GAL1 mRNA CTD PMID:22839698 NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO zinc protoporphyrin inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein] CTD PMID:19061877 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP
ISO 		zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]; zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]
zinc protoporphyrin inhibits the reaction [Nicotine results in increased phosphorylation of STAT3 protein] 		CTD PMID:24095726 PMID:24810525 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression
decreases secretion
increases expression 		EXP zinc protoporphyrin affects the expression of TGFB1
zinc protoporphyrin results in decreased secretion of TGFB1 protein
zinc protoporphyrin results in increased expression of TGFB1 protein 		CTD PMID:21163135 PMID:23525258 PMID:23704825 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression
multiple interactions 		EXP
ISO 		zinc protoporphyrin affects the expression of TIMP1
zinc protoporphyrin promotes the reaction [ALB protein results in increased expression of TIMP1 protein] 		CTD PMID:21163135 PMID:23704825 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions EXP zinc protoporphyrin promotes the reaction [TLR2 protein binds to MYD88 protein] CTD PMID:25780291 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP zinc protoporphyrin promotes the reaction [TLR4 protein binds to MYD88 protein] CTD PMID:25780291 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [cilostazol results in decreased susceptibility to TNF protein]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to NCF1 protein]]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of IL6 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]
[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of TNF mRNA; [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of TNF protein; zinc protoporphyrin inhibits the reaction [ADIPOQ protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; zinc protoporphyrin inhibits the reaction [naringenin results in decreased activity of TNF protein]; zinc protoporphyrin inhibits the reaction [perflexane inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [Tadalafil inhibits the reaction [Cisplatin results in increased expression of TNF protein]]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TNF mRNA]; zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of TNF protein]
zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; zinc protoporphyrin inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased localization of and results in increased activity of RELA protein]]; zinc protoporphyrin inhibits the reaction [manganese chloride promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [Nicotine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; zinc protoporphyrin inhibits the reaction [sesamol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] 		CTD PMID:19608869 PMID:20052772 PMID:20131233 PMID:20360627 PMID:21660147 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [SRC protein binds to TNFRSF1A protein]]] CTD PMID:19608869 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of TNRC6A mRNA CTD PMID:22839698 NCBI chr 1:186,992,457...187,146,764
Ensembl chr 1:186,992,504...187,146,756 		JBrowse link
G Tollip toll interacting protein decreases expression EXP zinc protoporphyrin results in decreased expression of TOLLIP protein CTD PMID:25780291 NCBI chr 1:206,391,120...206,413,809
Ensembl chr 1:206,380,308...206,411,988 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO
EXP 		[zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [cobaltiprotoporphyrin results in increased expression of TP53 protein]
zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in decreased expression of TP53 protein]
zinc protoporphyrin inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in increased expression of TRP53 protein]] 		CTD PMID:18042465 PMID:20357190 PMID:22763982 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP zinc protoporphyrin promotes the reaction [TRAF6 protein binds to MYD88 protein] CTD PMID:25780291 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Ubxn2a UBX domain protein 2A multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of UBXN2A mRNA CTD PMID:22839698 NCBI chr 6:33,603,804...33,645,958
Ensembl chr 6:33,603,804...33,632,202
Ensembl chr20:33,603,804...33,632,202 		JBrowse link
G Usp13 ubiquitin specific peptidase 13 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of USP13 mRNA CTD PMID:22839698 NCBI chr 2:117,502,811...117,617,049
Ensembl chr 2:117,505,122...117,630,161 		JBrowse link
G Usp34 ubiquitin specific peptidase 34 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of USP34 mRNA CTD PMID:22839698 NCBI chr14:101,487,110...101,677,519
Ensembl chr14:101,487,153...101,678,632 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO
EXP 		zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]; zinc protoporphyrin inhibits the reaction [HMOX1 protein inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]
zinc protoporphyrin promotes the reaction [Indomethacin results in increased expression of VCAM1 mRNA] 		CTD PMID:19608869 PMID:23892052 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vdr vitamin D receptor affects abundance ISO VDR gene polymorphism affects the abundance of zinc protoporphyrin CTD PMID:25963508 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of VPS33A mRNA CTD PMID:22839698 NCBI chr12:38,685,484...38,710,668
Ensembl chr12:38,685,538...38,712,277 		JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of WSB2 mRNA CTD PMID:22839698 NCBI chr12:44,878,483...44,899,474
Ensembl chr12:44,878,509...44,899,474 		JBrowse link
G Zfp36 zinc finger protein 36 multiple interactions ISO zinc protoporphyrin inhibits the reaction [[Nicotine co-treated with Lipopolysaccharides] results in increased expression of ZFP36 mRNA]; zinc protoporphyrin inhibits the reaction [cobaltiprotoporphyrin results in increased expression of ZFP36 mRNA]; zinc protoporphyrin inhibits the reaction [Hemin results in increased expression of ZFP36 mRNA]; zinc protoporphyrin inhibits the reaction [Nicotine results in increased expression of ZFP36 mRNA] CTD PMID:24095726 NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:92,796,628...92,799,108 		JBrowse link
G Zfp827 zinc finger protein 827 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in increased expression of ZNF827 mRNA CTD PMID:22839698 NCBI chr19:45,624,849...45,791,739
Ensembl chr19:45,614,604...45,844,430 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 multiple interactions ISO [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of ZFYVE16 mRNA CTD PMID:22839698 NCBI chr 2:25,448,264...25,495,180
Ensembl chr 2:25,448,829...25,483,295 		JBrowse link
zinc pyrithione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 increases expression ISO pyrithione zinc results in increased expression of ANXA5 mRNA CTD PMID:21424779 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO pyrithione zinc results in increased expression of BAX mRNA; pyrithione zinc results in increased expression of BAX protein CTD PMID:20151177 PMID:21424779 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO pyrithione zinc results in increased expression of BBC3 protein CTD PMID:20151177 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO pyrithione zinc results in decreased expression of BCL2L1 mRNA CTD PMID:21424779 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage ISO pyrithione zinc results in increased cleavage of BID protein CTD PMID:20151177 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Casp1 caspase 1 increases expression ISO pyrithione zinc results in increased expression of CASP1 mRNA CTD PMID:21424779 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 increases activity ISO pyrithione zinc results in increased activity of CASP3 protein CTD PMID:20151177 PMID:21557991 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity ISO pyrithione zinc results in increased activity of CASP7 protein CTD PMID:20151177 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases activity
increases expression 		ISO pyrithione zinc results in increased activity of CASP8 protein
pyrithione zinc results in increased expression of CASP8 mRNA 		CTD PMID:20151177 PMID:21424779 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO pyrithione zinc results in increased activity of CASP9 protein CTD PMID:20151177 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccng1 cyclin G1 decreases expression ISO pyrithione zinc results in decreased expression of CCNG1 mRNA CTD PMID:21424779 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO pyrithione zinc results in increased expression of CDKN1A mRNA; pyrithione zinc results in increased expression of CDKN1A protein CTD PMID:21424779 PMID:21557991 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects expression ISO pyrithione zinc affects the expression of CDKN2A protein CTD PMID:21557991 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO pyrithione zinc results in increased expression of CHEK2 mRNA CTD PMID:21424779 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Cryab crystallin, alpha B increases expression ISO pyrithione zinc results in increased expression of CRYAB mRNA; pyrithione zinc results in increased expression of CRYAB protein CTD PMID:19809895 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Ctsd cathepsin D increases expression ISO pyrithione zinc results in increased expression of CTSD protein CTD PMID:20151177 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Cycs cytochrome c, somatic affects localization ISO pyrithione zinc affects the localization of CYCS protein CTD PMID:21557991 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO pyrithione zinc results in increased expression of CYP1A1 mRNA CTD PMID:21424779 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO pyrithione zinc results in increased expression of CYP7A1 mRNA CTD PMID:21424779 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 increases expression ISO pyrithione zinc results in increased expression of DDB1 mRNA CTD PMID:21424779 NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO pyrithione zinc results in increased expression of DDIT3 mRNA CTD PMID:21424779 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO pyrithione zinc results in increased expression of DNAJA1 mRNA; pyrithione zinc results in increased expression of DNAJA1 protein CTD PMID:19809895 PMID:21424779 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO pyrithione zinc results in increased expression of DNAJB4 mRNA CTD PMID:21424779 NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042 		JBrowse link
G Egr1 early growth response 1 increases expression ISO pyrithione zinc results in increased expression of EGR1 mRNA CTD PMID:19809895 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression ISO pyrithione zinc results in increased expression of EPHX2 mRNA CTD PMID:21424779 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases expression ISO pyrithione zinc results in increased expression of FMO1 mRNA CTD PMID:21424779 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression
increases expression 		ISO pyrithione zinc results in decreased expression of FMO5 mRNA
pyrithione zinc results in increased expression of FMO5 mRNA 		CTD PMID:21424779 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO pyrithione zinc results in increased expression of GADD45A mRNA CTD PMID:21424779 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO pyrithione zinc results in increased expression of GDF15 mRNA CTD PMID:21424779 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO pyrithione zinc results in increased expression of GPX1 mRNA CTD PMID:21424779 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO pyrithione zinc results in increased expression of GSR mRNA CTD PMID:21424779 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO pyrithione zinc results in increased expression of GSTM3 mRNA CTD PMID:21424779 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		ISO pyrithione zinc results in increased expression of HMOX1 mRNA; pyrithione zinc results in increased expression of HMOX1 protein
MTF1 gene mutant form promotes the reaction [pyrithione zinc results in increased expression of HMOX1 mRNA] 		CTD PMID:19809895 PMID:21424779 PMID:23085594 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases expression ISO pyrithione zinc results in increased expression of HSF1 mRNA CTD PMID:21424779 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO pyrithione zinc results in increased expression of HSP90AA1 mRNA CTD PMID:21424779 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression ISO pyrithione zinc results in increased expression of HSP90AB1 mRNA CTD PMID:21424779 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO pyrithione zinc results in increased expression of HSPA1A mRNA; pyrithione zinc results in increased expression of HSPA1A protein CTD PMID:19809895 PMID:21424779 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression ISO pyrithione zinc results in increased expression of HSPA1L mRNA; pyrithione zinc results in increased expression of HSPA1L protein CTD PMID:19809895 PMID:21424779 NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO pyrithione zinc results in increased expression of HSPA4 mRNA CTD PMID:21424779 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO pyrithione zinc results in increased expression of HSPA5 mRNA CTD PMID:21424779 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO pyrithione zinc results in increased expression of HSPA6 mRNA; pyrithione zinc results in increased expression of HSPA6 protein CTD PMID:19809895 PMID:21424779 NCBI chr13:85,805,911...85,807,052 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO pyrithione zinc results in increased expression of HSPA8 mRNA CTD PMID:21424779 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO pyrithione zinc results in increased expression of HSPD1 mRNA CTD PMID:21424779 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO pyrithione zinc results in increased expression of HSPE1 mRNA CTD PMID:21424779 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO pyrithione zinc results in increased expression of HSPH1 mRNA CTD PMID:21424779 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression ISO pyrithione zinc results in decreased expression of IGFBP6 mRNA CTD PMID:21424779 NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO pyrithione zinc results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Lta lymphotoxin alpha increases expression ISO pyrithione zinc results in increased expression of LTA mRNA CTD PMID:21424779 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO pyrithione zinc results in increased expression of MDM2 mRNA CTD PMID:21424779 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mt1a metallothionein 1A increases expression ISO pyrithione zinc results in increased expression of MT1 mRNA CTD PMID:23085594 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mt2 metallothionein 2 increases expression
multiple interactions 		ISO pyrithione zinc results in increased expression of MT2A mRNA; pyrithione zinc results in increased expression of MT2A protein
[zinc chloride co-treated with pyrithione zinc] results in increased expression of MT2A mRNA 		CTD PMID:20151177 PMID:20801194 PMID:21424779 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 gene mutant form promotes the reaction [pyrithione zinc results in increased expression of HMOX1 mRNA] CTD PMID:23085594 NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression ISO pyrithione zinc results in decreased expression of MTOR protein CTD PMID:21557991 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions 		ISO pyrithione zinc results in increased expression of NFE2L2 protein
SQSTM1 protein affects the reaction [pyrithione zinc results in increased expression of NFE2L2 protein] 		CTD PMID:30261176 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO pyrithione zinc results in increased expression of NFKB1 mRNA CTD PMID:21424779 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO pyrithione zinc results in decreased expression of NFKBIA mRNA CTD PMID:21424779 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO pyrithione zinc results in increased expression of NOS2A mRNA CTD PMID:21424779 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
affects response to substance
increases activity 		ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased activity of PARP1 protein]
PARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]
PARP1 protein affects the susceptibility to pyrithione zinc 		CTD PMID:19809895 PMID:21424779 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression ISO pyrithione zinc results in decreased expression of POR mRNA CTD PMID:21424779 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO pyrithione zinc results in increased expression of PRDX1 mRNA CTD PMID:21424779 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO pyrithione zinc results in decreased expression of PTGS1 mRNA CTD PMID:21424779 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein increases expression ISO pyrithione zinc results in increased expression of RAD23A mRNA CTD PMID:21424779 NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543 		JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO pyrithione zinc results in increased expression of RAD50 mRNA CTD PMID:21424779 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Rps6 ribosomal protein S6 affects phosphorylation ISO pyrithione zinc affects the phosphorylation of RPS6 protein CTD PMID:21557991 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO pyrithione zinc results in decreased expression of SERPINE1 mRNA CTD PMID:21424779 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO pyrithione zinc results in increased expression of SOD1 mRNA CTD PMID:21424779 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO pyrithione zinc results in increased expression of SOD2 mRNA CTD PMID:21424779 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO SQSTM1 protein affects the reaction [pyrithione zinc results in increased expression of NFE2L2 protein] CTD PMID:30261176 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO pyrithione zinc results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO pyrithione zinc results in increased expression of TNF mRNA CTD PMID:21424779 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO Pentetic Acid inhibits the reaction [pyrithione zinc results in increased expression of TP53 protein]; Pentetic Acid inhibits the reaction [pyrithione zinc results in increased phosphorylation of TP53 protein]; pyrithione zinc results in increased expression of and results in increased phosphorylation of TP53 protein; pyrithione zinc results in increased phosphorylation of and results in increased activity of TP53 protein
pyrithione zinc results in increased expression of TP53 mRNA; pyrithione zinc results in increased expression of TP53 protein 		CTD PMID:20151177 PMID:21424779 PMID:21557991 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ung uracil-DNA glycosylase increases expression ISO pyrithione zinc results in increased expression of UNG mRNA CTD PMID:21424779 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
zineb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases expression EXP Zineb results in decreased expression of ACHE protein CTD PMID:3868355 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Zineb inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Casp3 caspase 3 increases activity ISO Zineb results in increased activity of CASP3 protein CTD PMID:17189834 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Zineb results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity 		ISO [Endosulfan co-treated with Zineb] results in increased activity of NFKB1 protein
Zineb results in increased activity of NFKB1 protein 		CTD PMID:17189834 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO Zineb inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; Zineb inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein] CTD PMID:29149346 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO Zineb results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Zineb inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Zineb promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] 		CTD PMID:15256756 PMID:16112155 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tpo thyroid peroxidase decreases activity ISO Zineb results in decreased activity of TPO protein CTD PMID:9248629 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      molecular entity 20871
        polyatomic entity 20745
          heteroatomic molecular entity 20606
            coordination entity 16221
              zinc group coordination entity 13147
                zinc coordination entity 308
                  diaminozinc 0
                  metiram 24
                  nickel-zinc ferrite 0
                  propineb 1
                  tetrachlorozincate(2-) + 0
                  zinc ferrite 0
                  zinc pyrithione 72
                  zinc tetrapyrrole + 158
                  zineb + 117
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  metal atom 18447
                    transition element atom 17990
                      d-block element atom 17985
                        zinc group element atom 14310
                          zinc atom 2866
                            zinc molecular entity 2866
                              zinc coordination entity 308
                                diaminozinc 0
                                metiram 24
                                nickel-zinc ferrite 0
                                propineb 1
                                tetrachlorozincate(2-) + 0
                                zinc ferrite 0
                                zinc pyrithione 72
                                zinc tetrapyrrole + 158
                                zineb + 117
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