CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: octadecanoid
Accession: CHEBI:36326
browse the term
Definition: Unsaturated C18 fatty acids and skeletally related compounds.
Synonyms: related_synonym: octadecanoids
cyclic_relationship: is_conjugate_acid_of CHEBI:131860
G
Cd36
CD36 molecule
increases expression
ISO
9,11-linoleic acid results in increased expression of CD36 mRNA
CTD
PMID:18155510
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Foxo1
forkhead box O1
affects localization
ISO
9,11-linoleic acid affects the localization of FOXO1 protein
CTD
PMID:15992797
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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Ppara
peroxisome proliferator activated receptor alpha
affects binding
ISO
9,11-linoleic acid binds to PPARA protein
CTD
PMID:23843199
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Ppard
peroxisome proliferator-activated receptor delta
affects binding
ISO
9,11-linoleic acid binds to PPARB protein
CTD
PMID:23843199
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
G
Pparg
peroxisome proliferator-activated receptor gamma
affects binding increases activity
ISO
9,11-linoleic acid binds to PPARG protein 9,11-linoleic acid results in increased activity of PPARG protein
CTD
PMID:18155510 PMID:23843199
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Tp53
tumor protein p53
multiple interactions
ISO
9,11-linoleic acid results in increased phosphorylation of and affects the localization of TP53 protein
CTD
PMID:15992797
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Abca1
ATP binding cassette subfamily A member 1
decreases expression
ISO
trilinolein results in decreased expression of ABCA1 mRNA
CTD
PMID:18356535
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcg5
ATP binding cassette subfamily G member 5
decreases expression
ISO
trilinolein results in decreased expression of ABCG5 mRNA
CTD
PMID:18356535
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abcg8
ATP binding cassette subfamily G member 8
decreases expression
ISO
trilinolein results in decreased expression of ABCG8 mRNA
CTD
PMID:18356535
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
decreases expression
ISO
trilinolein results in decreased expression of CYP27A1 mRNA
CTD
PMID:18356535
NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
trilinolein results in increased expression of HMGCR mRNA
CTD
PMID:18356535
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Mttp
microsomal triglyceride transfer protein
increases expression
ISO
trilinolein results in increased expression of MTTP mRNA
CTD
PMID:18356535
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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Npc1l1
NPC1 like intracellular cholesterol transporter 1
decreases expression
ISO
trilinolein results in decreased expression of NPC1L1 mRNA
CTD
PMID:18356535
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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Scd
stearoyl-CoA desaturase
multiple interactions decreases expression
ISO
Clofibrate inhibits the reaction [trilinolein results in decreased expression of SCD1 mRNA]
CTD
PMID:8790349
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Fech
ferrochelatase
affects abundance
ISO
FECH protein affects the abundance of 1-palmitoyl-2-linoleoylphosphatidylcholine
CTD
PMID:29906468
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
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Lipc
lipase C, hepatic type
decreases abundance
ISO
LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
decreases abundance
ISO
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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Cat
catalase
increases expression
ISO
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAT protein
CTD
PMID:10946007
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav1
caveolin 1
increases expression
ISO
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAV1 mRNA
CTD
PMID:27257344
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
EXP
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein
CTD
PMID:22135674
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Egr1
early growth response 1
multiple interactions
EXP
[13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein
CTD
PMID:22135674
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Ppara
peroxisome proliferator activated receptor alpha
increases expression
EXP
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARA protein
CTD
PMID:22135674
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
increases expression
EXP
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARG protein
CTD
PMID:22135674
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Gsta1
glutathione S-transferase alpha 1
affects metabolic processing
ISO
GSTA1 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid
CTD
PMID:12031293
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Gsta4
glutathione S-transferase alpha 4
affects metabolic processing
ISO
GSTA4 protein affects the metabolism of 13-oxo-9,11-octadecadienoic acid
CTD
PMID:12031293
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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Ephx3
epoxide hydrolase 3
multiple interactions
ISO
[EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] results in decreased abundance of [9,10,13-trihydroxy-11-octadecenoic acid binds to Ceramides]; [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] which results in decreased chemical synthesis of 9,10,13-trihydroxy-11-octadecenoic acid
CTD
PMID:33334892
NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122
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Adipor1
adiponectin receptor 1
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of ADIPOR1 mRNA
CTD
PMID:17408517
NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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Adipor2
adiponectin receptor 2
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of ADIPOR2 mRNA
CTD
PMID:17408517
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
G
Cd68
Cd68 molecule
affects expression
ISO
cis-9, trans-11-conjugated linoleic acid affects the expression of CD68 mRNA
CTD
PMID:17327424
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cycs
cytochrome c, somatic
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased activity of CYCS protein
CTD
PMID:17408517
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Fmo3
flavin containing dimethylaniline monoxygenase 3
decreases expression
ISO
cis-9, trans-11-conjugated linoleic acid results in decreased expression of FMO3 mRNA
CTD
PMID:17217560
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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Gsr
glutathione-disulfide reductase
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased activity of GSR protein
CTD
PMID:17408517
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Ins1
insulin 1
multiple interactions
ISO
cis-9, trans-11-conjugated linoleic acid promotes the reaction [INS1 protein affects the transport of Glucose]
CTD
PMID:17327424
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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Insr
insulin receptor
affects expression
ISO
cis-9, trans-11-conjugated linoleic acid affects the expression of INSR protein
CTD
PMID:17327424
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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Irs1
insulin receptor substrate 1
multiple interactions
EXP ISO
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in decreased phosphorylation of IRS1 protein cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of IRS1 mRNA]
CTD
PMID:17327424 PMID:17408517
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
EXP
[cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased phosphorylation of and results in increased activity of MAP2K1 protein; cis-9, trans-11-conjugated linoleic acid results in increased phosphorylation of and results in increased activity of MAP2K1 protein
CTD
PMID:17869086
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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Map2k3
mitogen activated protein kinase kinase 3
multiple interactions
EXP
[cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased phosphorylation of and results in increased activity of MAP2K3 protein; cis-9, trans-11-conjugated linoleic acid results in increased phosphorylation of and results in increased activity of MAP2K3 protein
CTD
PMID:17869086
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
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Me1
malic enzyme 1
increases expression
ISO
cis-9, trans-11-conjugated linoleic acid results in increased expression of ME1 mRNA
CTD
PMID:17217560
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Nfkb1
nuclear factor kappa B subunit 1
affects activity
ISO
cis-9, trans-11-conjugated linoleic acid affects the activity of NFKB1 protein
CTD
PMID:17327424
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkb2
nuclear factor kappa B subunit 2
affects activity
ISO
cis-9, trans-11-conjugated linoleic acid affects the activity of NFKB2 protein
CTD
PMID:17327424
NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
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Nr1h3
nuclear receptor subfamily 1, group H, member 3
affects expression
ISO
cis-9, trans-11-conjugated linoleic acid affects the expression of NR1H3 mRNA
CTD
PMID:17327424
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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Por
cytochrome p450 oxidoreductase
decreases expression
ISO
cis-9, trans-11-conjugated linoleic acid results in decreased expression of POR mRNA
CTD
PMID:17217560
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of PPARA mRNA; [trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased expression of PPARA protein
CTD
PMID:17408517
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased expression of PPARG protein]; [cis-9, trans-11-conjugated linoleic acid co-treated with trans-10,cis-12-conjugated linoleic acid] results in increased expression of PPARG protein
CTD
PMID:36875279
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Rel
REL proto-oncogene, NF-kB subunit
affects activity
ISO
cis-9, trans-11-conjugated linoleic acid affects the activity of REL protein
CTD
PMID:17327424
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
cis-9, trans-11-conjugated linoleic acid affects the expression of and affects the activity of RELA protein
CTD
PMID:17327424
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Relb
RELB proto-oncogene, NF-kB subunit
affects activity
ISO
cis-9, trans-11-conjugated linoleic acid affects the activity of RELB protein
CTD
PMID:17327424
NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
G
Scd
stearoyl-CoA desaturase
increases expression
ISO
cis-9, trans-11-conjugated linoleic acid results in increased expression of SCD1 mRNA
CTD
PMID:17217560
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Slc2a4
solute carrier family 2 member 4
increases expression multiple interactions
ISO
cis-9, trans-11-conjugated linoleic acid results in increased expression of SLC2A4 protein cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of SLC2A4 mRNA]
CTD
PMID:17327424
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Sod2
superoxide dismutase 2
multiple interactions
EXP
[trans-10,cis-12-conjugated linoleic acid co-treated with cis-9, trans-11-conjugated linoleic acid] results in increased activity of SOD2 protein
CTD
PMID:17408517
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Srebf1
sterol regulatory element binding transcription factor 1
affects expression
ISO
cis-9, trans-11-conjugated linoleic acid affects the expression of SREBF1 mRNA
CTD
PMID:17327424
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Tnf
tumor necrosis factor
multiple interactions affects expression
ISO
cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of IRS1 mRNA]; cis-9, trans-11-conjugated linoleic acid inhibits the reaction [TNF protein results in decreased expression of SLC2A4 mRNA] cis-9, trans-11-conjugated linoleic acid affects the expression of TNF mRNA
CTD
PMID:17327424
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Pparg
peroxisome proliferator-activated receptor gamma
increases expression
ISO
9-hydroxy-10,12-octadecadienoic acid results in increased expression of PPARG
CTD
PMID:16647253
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Alox15
arachidonate 15-lipoxygenase
multiple interactions
ISO
[caffeic acid results in decreased activity of ALOX15 protein] which results in decreased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [caffeic acid results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; [Masoprocol results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [Sulindac results in increased expression of ALOX15 protein] which results in increased chemical synthesis of 13-hydroxy-9,11-octadecadienoic acid; [Vorinostat results in increased expression of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid
CTD
PMID:11406566 PMID:15574791
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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Cat
catalase
increases expression
ISO
13-hydroxy-9,11-octadecadienoic acid results in increased expression of CAT protein
CTD
PMID:10946007
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Lipc
lipase C, hepatic type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
G
Lipg
lipase G, endothelial type
multiple interactions affects abundance
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate LIPG gene mutant form affects the abundance of cholesteryl linoleate
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
G
Adgre1
adhesion G protein-coupled receptor E1
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of ADGRE1 mRNA; Linoleic Acids, Conjugated results in increased expression of ADGRE1 protein
CTD
PMID:17322064
NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
G
Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions decreases expression
EXP ISO
[picolinic acid co-treated with Linoleic Acids, Conjugated] results in increased expression of ADIPOQ protein Linoleic Acids, Conjugated results in decreased expression of ADIPOQ protein
CTD
PMID:17199723 PMID:17322064
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Adipor2
adiponectin receptor 2
decreases expression multiple interactions
ISO
Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of ADIPOR2 mRNA]
CTD
PMID:17322064
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
G
Apoc2
apolipoprotein C2
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of APOC2 mRNA
CTD
PMID:17322064
NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of BAX protein
CTD
PMID:20155912
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
Linoleic Acids, Conjugated results in decreased expression of BCL2 protein
CTD
PMID:15961301 PMID:20155912
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Casp3
caspase 3
increases activity
ISO
Linoleic Acids, Conjugated results in increased activity of CASP3 protein
CTD
PMID:20155912
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of CASP8 protein
CTD
PMID:20155912
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Cd36
CD36 molecule
decreases expression multiple interactions
ISO
Linoleic Acids, Conjugated results in decreased expression of CD36 mRNA rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of CD36 mRNA]
CTD
PMID:17322064
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cd68
Cd68 molecule
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of CD68 mRNA
CTD
PMID:17322064
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
G
Esr1
estrogen receptor 1
multiple interactions
ISO
Linoleic Acids, Conjugated results in decreased phosphorylation of and results in decreased activity of ESR1 protein; Okadaic Acid inhibits the reaction [Linoleic Acids, Conjugated results in decreased phosphorylation of ESR1 protein]
CTD
PMID:19800873
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of GADD45A protein
CTD
PMID:15961301
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases activity multiple interactions increases expression
ISO
Linoleic Acids, Conjugated results in increased activity of GCLC protein [Linoleic Acids, Conjugated results in increased activity of GCLC protein] which results in decreased susceptibility to tert-Butylhydroperoxide Linoleic Acids, Conjugated results in increased expression of GCLC mRNA
CTD
PMID:17092368
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gpx4
glutathione peroxidase 4
multiple interactions
ISO
Linoleic Acids, Conjugated promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]
CTD
PMID:14642406
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Gsk3b
glycogen synthase kinase 3 beta
increases activity decreases phosphorylation
ISO
Linoleic Acids, Conjugated results in increased activity of GSK3B protein Linoleic Acids, Conjugated results in decreased phosphorylation of GSK3B protein
CTD
PMID:19800873
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Icam1
intercellular adhesion molecule 1
decreases expression
ISO
Linoleic Acids, Conjugated results in decreased expression of ICAM1 protein
CTD
PMID:19800873
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Il1b
interleukin 1 beta
increases expression multiple interactions
ISO
Linoleic Acids, Conjugated results in increased expression of IL1B mRNA resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of IL1B mRNA]
CTD
PMID:18776171
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
increases expression decreases expression multiple interactions
ISO
Linoleic Acids, Conjugated results in increased expression of IL6 mRNA; Linoleic Acids, Conjugated results in increased expression of IL6 protein Linoleic Acids, Conjugated results in decreased expression of IL6 protein [Chromium co-treated with Linoleic Acids, Conjugated] results in decreased expression of IL6 protein resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of IL6 mRNA]
CTD
PMID:16933788 PMID:18776171
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ins1
insulin 1
multiple interactions decreases expression
ISO
[Linoleic Acids, Conjugated co-treated with Chromium] results in decreased expression of INS1 protein Linoleic Acids, Conjugated results in decreased expression of INS1 protein
CTD
PMID:16933788
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Ins2
insulin 2
decreases expression increases response to substance
ISO
Linoleic Acids, Conjugated results in decreased expression of INS protein Linoleic Acids, Conjugated results in increased susceptibility to INS protein
CTD
PMID:23073171
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Lep
leptin
multiple interactions decreases expression increases expression
ISO
[Linoleic Acids, Conjugated co-treated with Chromium] results in decreased expression of LEP protein Linoleic Acids, Conjugated results in decreased expression of LEP protein Linoleic Acids, Conjugated results in increased expression of LEP protein
CTD
PMID:16933788 PMID:17322064
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lpl
lipoprotein lipase
multiple interactions increases activity decreases expression
ISO
rosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of LPL mRNA] Linoleic Acids, Conjugated results in increased activity of LPL protein
CTD
PMID:17322064 PMID:23073171
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
G
Mmp2
matrix metallopeptidase 2
decreases activity
ISO
Linoleic Acids, Conjugated results in decreased activity of MMP2 protein
CTD
PMID:19800873
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Ogdh
oxoglutarate dehydrogenase
multiple interactions increases activity
EXP
Linoleic Acids, Conjugated inhibits the reaction [Acrolein results in decreased activity of OGDH protein] Linoleic Acids, Conjugated results in increased activity of OGDH protein
CTD
PMID:34238125
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
G
Pik3r1
phosphoinositide-3-kinase regulatory subunit 1
decreases expression
ISO
Linoleic Acids, Conjugated results in decreased expression of PIK3R1 protein
CTD
PMID:19800873
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
G
Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
Linoleic Acids, Conjugated binds to and results in increased activity of PPARA protein
CTD
PMID:16731579
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Ppard
peroxisome proliferator-activated receptor delta
multiple interactions
ISO EXP
Linoleic Acids, Conjugated binds to and results in increased activity of PPARB protein
CTD
PMID:16731579
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases activity increases expression multiple interactions decreases expression
ISO
Linoleic Acids, Conjugated results in decreased activity of PPARG protein Linoleic Acids, Conjugated results in increased expression of PPARG mRNA Linoleic Acids, Conjugated results in increased expression of PPARG mRNA; Linoleic Acids, Conjugated results in increased expression of PPARG protein Linoleic Acids, Conjugated results in increased phosphorylation of and results in increased activity of PPARG protein; resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in decreased activity of PPARG protein]; resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased phosphorylation of and results in increased activity of PPARG protein] Linoleic Acids, Conjugated results in decreased expression of PPARG protein
CTD
PMID:15961301 PMID:16933788 PMID:17322064 PMID:18776171
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
ISO
Linoleic Acids, Conjugated results in increased expression of PTGS2 mRNA; Linoleic Acids, Conjugated results in increased expression of PTGS2 protein [Linoleic Acids, Conjugated results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprost; Resveratrol inhibits the reaction [[Linoleic Acids, Conjugated results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprost]; Resveratrol inhibits the reaction [Linoleic Acids, Conjugated results in increased expression of PTGS2 mRNA]
CTD
PMID:18776171
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Rxra
retinoid X receptor alpha
multiple interactions
ISO
Linoleic Acids, Conjugated binds to and results in increased activity of RXRA protein
CTD
PMID:16731579
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
G
Scd2
stearoyl-Coenzyme A desaturase 2
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of SCD mRNA
CTD
PMID:17322064
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
G
Sod2
superoxide dismutase 2
multiple interactions
EXP
Linoleic Acids, Conjugated inhibits the reaction [Acrolein results in decreased activity of SOD2 protein]
CTD
PMID:34238125
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Tnf
tumor necrosis factor
increases expression decreases expression
ISO
Linoleic Acids, Conjugated results in increased expression of TNF protein Linoleic Acids, Conjugated results in decreased expression of TNF protein
CTD
PMID:16933788
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tp53
tumor protein p53
increases expression
ISO
Linoleic Acids, Conjugated results in increased expression of TP53 protein
CTD
PMID:15961301
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Abcg8
ATP binding cassette subfamily G member 8
affects expression
EXP
Corn Oil affects the expression of ABCG8 mRNA
CTD
PMID:16360708
NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
G
Acaca
acetyl-CoA carboxylase alpha
increases expression
EXP
Corn Oil results in increased expression of ACACA mRNA
CTD
PMID:1973097
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acly
ATP citrate lyase
affects expression
EXP
Corn Oil affects the expression of ACLY mRNA
CTD
PMID:16360708
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
G
Acot2
acyl-CoA thioesterase 2
affects expression
EXP
Corn Oil affects the expression of ACOT2 mRNA
CTD
PMID:16360708
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
G
Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions
EXP
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]
CTD
PMID:29165388
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Akr1b7
aldo-keto reductase family 1, member B7
affects expression
EXP
Corn Oil affects the expression of AKR1B7 mRNA
CTD
PMID:16360708
NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
G
Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Corn Oil affects the expression of ALDH1A1 mRNA
CTD
PMID:16360708
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
G
Angptl4
angiopoietin-like 4
affects expression
EXP
Corn Oil affects the expression of ANGPTL4 mRNA
CTD
PMID:16360708
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
G
Areg
amphiregulin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA
CTD
PMID:32186404
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
G
Bad
BCL2-associated agonist of cell death
increases expression
EXP
Corn Oil results in increased expression of BAD mRNA
CTD
PMID:22760963
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Bdkrb1
bradykinin receptor B1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]
CTD
PMID:29165388
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
G
Bhlhe40
basic helix-loop-helix family, member e40
affects expression
EXP
Corn Oil affects the expression of BHLHE40 mRNA
CTD
PMID:16360708
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
G
Bhmt
betaine-homocysteine S-methyltransferase
affects expression
EXP
Corn Oil affects the expression of BHMT mRNA
CTD
PMID:16360708
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
G
Birc3
baculoviral IAP repeat-containing 3
increases expression
ISO
Corn Oil results in increased expression of BIRC3 mRNA
CTD
PMID:33263755
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
G
Bmp1
bone morphogenetic protein 1
affects expression
EXP
Corn Oil affects the expression of BMP1 mRNA
CTD
PMID:16360708
NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
G
Bmp2
bone morphogenetic protein 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA
CTD
PMID:32186404
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
G
Cadm1
cell adhesion molecule 1
affects expression
EXP
Corn Oil affects the expression of CADM1 mRNA
CTD
PMID:16360708
NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
G
Calca
calcitonin-related polypeptide alpha
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA
CTD
PMID:32186404
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
G
Car6
carbonic anhydrase 6
increases expression
ISO
Corn Oil results in increased expression of CAR6 mRNA
CTD
PMID:33263755
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
G
Card9
caspase recruitment domain family, member 9
increases expression
ISO
Corn Oil results in increased expression of CARD9 mRNA
CTD
PMID:33263755
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
G
Cat
catalase
multiple interactions decreases expression
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein
CTD
PMID:36432690
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Cav3
caveolin 3
decreases expression
ISO
Corn Oil results in decreased expression of CAV3 mRNA
CTD
PMID:33263755
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
G
Ccl3
C-C motif chemokine ligand 3
increases expression decreases expression
ISO EXP
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA
CTD
PMID:22760963 PMID:23409006
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Ccnd1
cyclin D1
affects expression
EXP
Corn Oil affects the expression of CCND1 mRNA
CTD
PMID:16360708
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cd36
CD36 molecule
decreases expression
EXP
Corn Oil results in decreased expression of CD36 mRNA
CTD
PMID:22760963
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cdhr1
cadherin-related family member 1
increases expression
EXP
Corn Oil results in increased expression of CDHR1 mRNA
CTD
PMID:22760963
NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
affects expression increases expression
EXP
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA
CTD
PMID:16360708 PMID:22760963
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Cenpt
centromere protein T
increases expression
EXP
Corn Oil results in increased expression of CENPT mRNA
CTD
PMID:22760963
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
G
Cfb
complement factor B
increases expression
EXP
Corn Oil results in increased expression of CFB mRNA
CTD
PMID:22760963
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cldn1
claudin 1
decreases expression
ISO
Corn Oil results in decreased expression of CLDN1 mRNA
CTD
PMID:33263755
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
G
Cldn9
claudin 9
increases expression
ISO
Corn Oil results in increased expression of CLDN9 mRNA
CTD
PMID:33263755
NCBI chr10:12,714,137...12,715,568
G
Cox7a1
cytochrome c oxidase subunit 7A1
decreases expression
ISO
Corn Oil results in decreased expression of COX7A1 mRNA
CTD
PMID:23409006
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression multiple interactions affects expression
EXP ISO
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA
CTD
PMID:16360708 PMID:22760963 PMID:36432690
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Cpt2
carnitine palmitoyltransferase 2
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA
CTD
PMID:36432690
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
G
Crot
carnitine O-octanoyltransferase
affects expression multiple interactions
EXP ISO
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA
CTD
PMID:16360708 PMID:36432690
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
G
Ctsg
cathepsin G
increases expression
EXP
Corn Oil results in increased expression of CTSG mRNA
CTD
PMID:22760963
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
G
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
affects expression
EXP
Corn Oil affects the expression of CYP17A1 mRNA
CTD
PMID:16360708
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
affects expression
EXP
Corn Oil affects the expression of CYP7A1 mRNA
CTD
PMID:16360708
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Cyp8b1
cytochrome P450 family 8 subfamily B member 1
affects expression
EXP
Corn Oil affects the expression of CYP8B1 mRNA
CTD
PMID:16360708
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
G
Ephx2
epoxide hydrolase 2
affects expression
EXP
Corn Oil affects the expression of EPHX2 mRNA
CTD
PMID:16360708
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
G
Ets1
ETS proto-oncogene 1, transcription factor
decreases expression
EXP
Corn Oil results in decreased expression of ETS1 mRNA
CTD
PMID:22760963
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
G
Fabp1
fatty acid binding protein 1
multiple interactions
EXP
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA
CTD
PMID:15016835
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
G
Fabp2
fatty acid binding protein 2
affects expression
EXP
Corn Oil affects the expression of FABP2 mRNA
CTD
PMID:16360708
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
G
Fabp7
fatty acid binding protein 7
affects expression
EXP
Corn Oil affects the expression of FABP7 mRNA
CTD
PMID:16360708
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
G
Fasn
fatty acid synthase
affects expression
EXP
Corn Oil affects the expression of FASN mRNA
CTD
PMID:16360708
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fcgrt
Fc gamma receptor and transporter
decreases expression
EXP
Corn Oil results in decreased expression of FCGRT mRNA
CTD
PMID:22760963
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
G
Fgb
fibrinogen beta chain
affects expression
EXP
Corn Oil affects the expression of FGB mRNA
CTD
PMID:16360708
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
G
Fgf21
fibroblast growth factor 21
affects expression
EXP
Corn Oil affects the expression of FGF21 mRNA
CTD
PMID:16360708
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
G
Fst
follistatin
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA
CTD
PMID:32186404
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
G0s2
G0/G1switch 2
affects expression
EXP
Corn Oil affects the expression of G0S2 mRNA
CTD
PMID:16360708
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
affects expression
EXP
Corn Oil affects the expression of GADD45A mRNA
CTD
PMID:16360708
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gal
galanin and GMAP prepropeptide
increases expression
EXP
Corn Oil results in increased expression of GAL mRNA
CTD
PMID:22760963
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gck
glucokinase
affects expression
EXP
Corn Oil affects the expression of GCK mRNA
CTD
PMID:16360708
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Gjd2
gap junction protein, delta 2
increases expression
ISO
Corn Oil results in increased expression of GJD2 mRNA
CTD
PMID:33263755
NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
G
Got1
glutamic-oxaloacetic transaminase 1
affects expression
EXP
Corn Oil affects the expression of GOT1 mRNA
CTD
PMID:16360708
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Got2
glutamic-oxaloacetic transaminase 2
decreases expression
EXP
Corn Oil results in decreased expression of GOT2 mRNA
CTD
PMID:34987138
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
affects expression
EXP
Corn Oil affects the expression of GPD2 mRNA
CTD
PMID:16360708
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]
CTD
PMID:29479035
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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H2ac25
H2A clustered histone 25
affects expression
EXP
Corn Oil affects the expression of H2A mRNA
CTD
PMID:16360708
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
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Hal
histidine ammonia lyase
affects expression
EXP
Corn Oil affects the expression of HAL mRNA
CTD
PMID:16360708
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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Hamp
hepcidin antimicrobial peptide
affects expression
EXP
Corn Oil affects the expression of HAMP mRNA
CTD
PMID:16360708
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
affects expression
EXP
Corn Oil affects the expression of HMGCR mRNA
CTD
PMID:16360708
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hoxa11
homeobox A11
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA
CTD
PMID:32186404
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
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Hp
haptoglobin
increases expression
EXP
Corn Oil results in increased expression of HP mRNA
CTD
PMID:22760963
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Corn Oil results in increased expression of HSP90AA1 mRNA
CTD
PMID:33263755
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Idi1
isopentenyl-diphosphate delta isomerase 1
affects expression
EXP
Corn Oil affects the expression of IDI1 mRNA
CTD
PMID:16360708
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
affects expression increases expression
EXP
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA
CTD
PMID:22760963
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
G
Igfbp1
insulin-like growth factor binding protein 1
affects expression
EXP
Corn Oil affects the expression of IGFBP1 mRNA
CTD
PMID:16360708
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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Ihh
Indian hedgehog signaling molecule
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA
CTD
PMID:32186404
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Il12b
interleukin 12B
increases secretion
EXP
Corn Oil results in increased secretion of IL12B protein
CTD
PMID:33263755
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il18
interleukin 18
increases expression
ISO
Corn Oil results in increased expression of IL18 mRNA
CTD
PMID:33263755
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1a
interleukin 1 alpha
increases secretion
EXP
Corn Oil results in increased secretion of IL1A protein
CTD
PMID:33263755
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
increases secretion
EXP
Corn Oil results in increased secretion of IL1B protein
CTD
PMID:33263755
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
Corn Oil results in increased expression of IL1RN mRNA
CTD
PMID:22760963
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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Il4
interleukin 4
increases expression increases secretion decreases expression
ISO EXP
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA
CTD
PMID:23409006 PMID:33263755
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il6r
interleukin 6 receptor
increases expression
EXP
Corn Oil results in increased expression of IL6R mRNA
CTD
PMID:22760963
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
G
Il9
interleukin 9
increases secretion
EXP
Corn Oil results in increased secretion of IL9 protein
CTD
PMID:33263755
NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
G
Inhbe
inhibin subunit beta E
affects expression
EXP
Corn Oil affects the expression of INHBE mRNA
CTD
PMID:16360708
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Ins1
insulin 1
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein]
CTD
PMID:29165388
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Irak1
interleukin-1 receptor-associated kinase 1
increases expression
ISO
Corn Oil results in increased expression of IRAK1 mRNA
CTD
PMID:33263755
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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Irf5
interferon regulatory factor 5
increases expression
ISO
Corn Oil results in increased expression of IRF5 mRNA
CTD
PMID:33263755
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
G
Irf7
interferon regulatory factor 7
increases expression
ISO
Corn Oil results in increased expression of IRF7 mRNA
CTD
PMID:33263755
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Corn Oil results in increased expression of JUN mRNA
CTD
PMID:33263755
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Klf2
KLF transcription factor 2
affects expression
EXP
Corn Oil affects the expression of KLF2 mRNA
CTD
PMID:16360708
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
G
Lcat
lecithin cholesterol acyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA
CTD
PMID:36432690
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
G
Lcn2
lipocalin 2
increases expression
EXP
Corn Oil results in increased expression of LCN2 mRNA
CTD
PMID:22760963
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Lep
leptin
multiple interactions
EXP
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein]
CTD
PMID:29165388
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lgals1
galectin 1
increases expression
EXP
Corn Oil results in increased expression of LGALS1 mRNA
CTD
PMID:22760963
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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Lox
lysyl oxidase
multiple interactions
ISO
Corn Oil results in increased activity of and results in increased cleavage of LOX protein
CTD
PMID:26240151
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Ly75
lymphocyte antigen 75
increases expression
EXP
Corn Oil results in increased expression of LY75 mRNA
CTD
PMID:22760963
NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
G
Map2k1
mitogen activated protein kinase kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAP2K1 mRNA
CTD
PMID:33263755
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k3
mitogen activated protein kinase kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAP2K3 mRNA
CTD
PMID:33263755
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
G
Map2k6
mitogen-activated protein kinase kinase 6
affects expression
EXP
Corn Oil affects the expression of MAP2K6 mRNA
CTD
PMID:16360708
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
G
Map3k7
mitogen activated protein kinase kinase kinase 7
increases expression
ISO
Corn Oil results in increased expression of MAP3K7 mRNA
CTD
PMID:33263755
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
G
Mapk1
mitogen activated protein kinase 1
increases expression
ISO
Corn Oil results in increased expression of MAPK1 mRNA
CTD
PMID:33263755
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk14
mitogen activated protein kinase 14
increases expression
ISO
Corn Oil results in increased expression of MAPK14 mRNA
CTD
PMID:33263755
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
G
Mapk3
mitogen activated protein kinase 3
increases expression
ISO
Corn Oil results in increased expression of MAPK3 mRNA
CTD
PMID:33263755
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mdm2
MDM2 proto-oncogene
decreases expression
EXP
Corn Oil results in decreased expression of MDM2 mRNA
CTD
PMID:22760963
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
G
Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression
EXP
Corn Oil results in increased expression of MGMT mRNA
CTD
PMID:22760963
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
G
Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
Corn Oil results in increased expression of MGST2 mRNA
CTD
PMID:22760963
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
G
Mlycd
malonyl-CoA decarboxylase
decreases expression
EXP
Corn Oil results in decreased expression of MLYCD mRNA
CTD
PMID:22760963
NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
G
Msmo1
methylsterol monooxygenase 1
affects expression
EXP
Corn Oil affects the expression of MSMO1 mRNA
CTD
PMID:16360708
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
G
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA
CTD
PMID:36432690
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
G
Mx2
MX dynamin like GTPase 2
affects expression
EXP
Corn Oil affects the expression of MX2 mRNA
CTD
PMID:16360708
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
G
Myd88
MYD88, innate immune signal transduction adaptor
increases expression
ISO
Corn Oil results in increased expression of MYD88 mRNA
CTD
PMID:33263755
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
G
Nfe2l2
NFE2 like bZIP transcription factor 2
decreases activity
ISO
Corn Oil results in decreased activity of NFE2L2 protein
CTD
PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkbia
NFKB inhibitor alpha
increases expression
ISO
Corn Oil results in increased expression of NFKBIA mRNA
CTD
PMID:33263755
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Nlrc4
NLR family, CARD domain containing 4
increases expression
ISO
Corn Oil results in increased expression of NLRC4 mRNA
CTD
PMID:33263755
NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
G
Nr1h4
nuclear receptor subfamily 1, group H, member 4
affects expression
EXP
Corn Oil affects the expression of NR1H4 mRNA
CTD
PMID:16360708
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
EXP
Corn Oil results in increased expression of NR4A2 mRNA
CTD
PMID:22760963
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
G
Nsmce3
NSE3 homolog, SMC5-SMC6 complex component
affects expression
EXP
Corn Oil affects the expression of NSMCE3 mRNA
CTD
PMID:16360708
NCBI chr 1:118,401,302...118,402,629
G
Oat
ornithine aminotransferase
affects expression
EXP
Corn Oil affects the expression of OAT mRNA
CTD
PMID:16360708
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
G
Osgin1
oxidative stress induced growth inhibitor 1
affects expression
EXP
Corn Oil affects the expression of OSGIN1 mRNA
CTD
PMID:16360708
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
P2rx5
purinergic receptor P2X 5
affects expression
EXP
Corn Oil affects the expression of P2RX5 mRNA
CTD
PMID:16360708
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
G
Pax8
paired box 8
affects expression
EXP
Corn Oil affects the expression of PAX8 mRNA
CTD
PMID:16360708
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
G
Pdgfa
platelet derived growth factor subunit A
affects expression
EXP
Corn Oil affects the expression of PDGFA mRNA
CTD
PMID:16360708
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
G
Pdgfrb
platelet derived growth factor receptor beta
increases expression
EXP
Corn Oil results in increased expression of PDGFRB mRNA
CTD
PMID:22760963
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
G
Pdlim1
PDZ and LIM domain 1
affects expression
EXP
Corn Oil affects the expression of PDLIM1 mRNA
CTD
PMID:16360708
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
G
Pdlim2
PDZ and LIM domain 2
affects expression
EXP
Corn Oil affects the expression of PDLIM2 mRNA
CTD
PMID:16360708
NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
G
Pgf
placental growth factor
increases expression
EXP
Corn Oil results in increased expression of PGF mRNA
CTD
PMID:22760963
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
G
Pgrmc2
progesterone receptor membrane component 2
affects expression
EXP
Corn Oil affects the expression of PGRMC2 mRNA
CTD
PMID:16360708
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
increases expression
ISO
Corn Oil results in increased expression of PIK3CA mRNA
CTD
PMID:33263755
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Plin2
perilipin 2
affects expression
EXP
Corn Oil affects the expression of PLIN2 mRNA
CTD
PMID:16360708
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Prlr
prolactin receptor
affects expression
EXP
Corn Oil affects the expression of PRLR mRNA
CTD
PMID:16360708
NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA
CTD
PMID:32186404
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptprf
protein tyrosine phosphatase, receptor type, F
affects expression
EXP
Corn Oil affects the expression of PTPRF mRNA
CTD
PMID:16360708
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
G
Pycard
PYD and CARD domain containing
increases expression
ISO
Corn Oil results in increased expression of PYCARD mRNA
CTD
PMID:33263755
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
G
Rac1
Rac family small GTPase 1
increases expression
ISO
Corn Oil results in increased expression of RAC1 mRNA
CTD
PMID:33263755
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
G
Ripk1
receptor interacting serine/threonine kinase 1
increases expression
ISO
Corn Oil results in increased expression of RIPK1 mRNA
CTD
PMID:33263755
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
G
Ripk2
receptor-interacting serine-threonine kinase 2
increases expression
ISO
Corn Oil results in increased expression of RIPK2 mRNA
CTD
PMID:33263755
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
RT1-A
RT1 class I, locus A
increases expression
EXP
Corn Oil results in increased expression of RT1-A mRNA
CTD
PMID:22760963
G
RT1-Bb
RT1 class II, locus Bb
increases expression
EXP
Corn Oil results in increased expression of RT1-BB mRNA
CTD
PMID:22760963
NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
G
RT1-CE11
RT1 class I, locus CE11
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE11 mRNA
CTD
PMID:22760963
NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
G
RT1-CE14
RT1 class I, locus CE14
increases expression
EXP
Corn Oil results in increased expression of RT1-CE14 mRNA
CTD
PMID:22760963
NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
G
RT1-CE15
RT1 class I, locus CE15
decreases expression
EXP
Corn Oil results in decreased expression of RT1-CE15 mRNA
CTD
PMID:22760963
NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
G
RT1-CE16
RT1 class I, locus CE16
increases expression
EXP
Corn Oil results in increased expression of RT1-CE16 mRNA
CTD
PMID:22760963
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
G
RT1-CE2
RT1 class I, locus CE2
increases expression
EXP
Corn Oil results in increased expression of RT1-CE2 mRNA
CTD
PMID:22760963
NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
G
RT1-CE3
RT1 class I, locus CE3
increases expression
EXP
Corn Oil results in increased expression of RT1-CE3 mRNA
CTD
PMID:22760963
NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
G
RT1-CE4
RT1 class I, locus CE4
increases expression
EXP
Corn Oil results in increased expression of RT1-CE4 mRNA
CTD
PMID:22760963
NCBI chr20:3,431,509...3,504,535
G
RT1-CE5
RT1 class I, locus CE5
increases expression
EXP
Corn Oil results in increased expression of RT1-CE5 mRNA
CTD
PMID:22760963
NCBI chr20:3,403,418...3,479,476
G
RT1-N1
RT1 class Ib, locus N1
decreases expression
EXP
Corn Oil results in decreased expression of RT1-N1 mRNA
CTD
PMID:22760963
G
S100a8
S100 calcium binding protein A8
increases expression
EXP
Corn Oil results in increased expression of S100A8 mRNA
CTD
PMID:22760963
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
G
S100a9
S100 calcium binding protein A9
increases expression
EXP
Corn Oil results in increased expression of S100A9 mRNA
CTD
PMID:22760963
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
G
Scd
stearoyl-CoA desaturase
affects expression
EXP
Corn Oil affects the expression of SCD1 mRNA
CTD
PMID:16360708
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn1b
sodium voltage-gated channel beta subunit 1
affects expression
EXP
Corn Oil affects the expression of SCN1B mRNA
CTD
PMID:16360708
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
G
Sds
serine dehydratase
affects expression
EXP
Corn Oil affects the expression of SDS mRNA
CTD
PMID:16360708
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
G
Sfrp2
secreted frizzled-related protein 2
decreases expression
EXP
Corn Oil results in decreased expression of SFRP2 mRNA
CTD
PMID:22760963
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
G
Slc25a20
solute carrier family 25 member 20
multiple interactions
ISO
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA
CTD
PMID:36432690
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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Slc25a25
solute carrier family 25 member 25
affects expression
EXP
Corn Oil affects the expression of SLC25A25 mRNA
CTD
PMID:16360708
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
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Sod1
superoxide dismutase 1
decreases activity multiple interactions
ISO
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]
CTD
PMID:17194920
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sparc
secreted protein acidic and cysteine rich
increases expression
EXP
Corn Oil results in increased expression of SPARC mRNA
CTD
PMID:22760963
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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Sqle
squalene epoxidase
affects expression
EXP
Corn Oil affects the expression of SQLE mRNA
CTD
PMID:16360708
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Srebf1
sterol regulatory element binding transcription factor 1
affects expression
EXP
Corn Oil affects the expression of SREBF1 mRNA
CTD
PMID:16360708
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Sstr3
somatostatin receptor 3
decreases expression
EXP
Corn Oil results in decreased expression of SSTR3 mRNA
CTD
PMID:22760963
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
G
Sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
increases expression
ISO
Corn Oil results in increased expression of SUGT1 mRNA
CTD
PMID:33263755
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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Syk
spleen associated tyrosine kinase
increases expression
ISO
Corn Oil results in increased expression of SYK mRNA
CTD
PMID:23409006
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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Tac1
tachykinin, precursor 1
decreases expression
EXP
Corn Oil results in decreased expression of TAC1 mRNA
CTD
PMID:22760963
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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Tat
tyrosine aminotransferase
affects expression
EXP
Corn Oil affects the expression of TAT mRNA
CTD
PMID:16360708
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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Tbc1d14
TBC1 domain family, member 14
affects expression
EXP
Corn Oil affects the expression of TBC1D14 mRNA
CTD
PMID:16360708
NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
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Tgfa
transforming growth factor alpha
decreases expression
EXP
Corn Oil results in decreased expression of TGFA mRNA
CTD
PMID:22760963
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Ticam1
TIR domain containing adaptor molecule 1
increases expression
ISO
Corn Oil results in increased expression of TICAM1 mRNA
CTD
PMID:33263755
NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
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Tjp2
tight junction protein 2
increases expression
ISO
Corn Oil results in increased expression of TJP2 mRNA
CTD
PMID:33263755
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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Tjp3
tight junction protein 3
increases expression
ISO
Corn Oil results in increased expression of TJP3 mRNA
CTD
PMID:33263755
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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Tnfrsf1a
TNF receptor superfamily member 1A
increases expression
ISO
Corn Oil results in increased expression of TNFRSF1A mRNA
CTD
PMID:33263755
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tollip
toll interacting protein
increases expression
ISO
Corn Oil results in increased expression of TOLLIP mRNA
CTD
PMID:33263755
NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625
G
Tpcn2
two pore segment channel 2
affects expression
EXP
Corn Oil affects the expression of TPCN2 mRNA
CTD
PMID:16360708
NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
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Tpt1
tumor protein, translationally-controlled 1
increases expression
EXP
Corn Oil results in increased expression of TPT1 mRNA
CTD
PMID:22760963
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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Vegfb
vascular endothelial growth factor B
decreases expression
EXP
Corn Oil results in decreased expression of VEGFB mRNA
CTD
PMID:22760963
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Vnn1
vanin 1
affects expression
EXP
Corn Oil affects the expression of VNN1 mRNA
CTD
PMID:16360708
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
Corn Oil results in decreased expression of XIAP mRNA
CTD
PMID:33263755
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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Xpnpep2
X-prolyl aminopeptidase 2
affects expression
EXP
Corn Oil affects the expression of XPNPEP2 mRNA
CTD
PMID:16360708
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Corn Oil affects the expression of ZDHHC23 mRNA
CTD
PMID:16360708
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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Pparg
peroxisome proliferator-activated receptor gamma
increases activity
ISO
linoleamide analog results in increased activity of PPARG protein
CTD
PMID:29288688
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Abca1
ATP binding cassette subfamily A member 1
multiple interactions decreases expression increases expression increases phosphorylation increases degradation
ISO
1-Butanol inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]]; Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Cholesterol]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Phospholipids]]; triacsin C inhibits the reaction [Linoleic Acid results in increased degradation of ABCA1 protein] Linoleic Acid analog results in decreased expression of ABCA1 mRNA Linoleic Acid results in increased expression of ABCA1 mRNA Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] Linoleic Acid results in increased phosphorylation of ABCA1 protein
CTD
PMID:16118212 PMID:18356535 PMID:27939595
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcg1
ATP binding cassette subfamily G member 1
decreases expression
ISO
Linoleic Acid results in decreased expression of ABCG1 mRNA; Linoleic Acid results in decreased expression of ABCG1 protein
CTD
PMID:16730733
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
G
Acaca
acetyl-CoA carboxylase alpha
decreases expression
EXP
Linoleic Acid results in decreased expression of ACACA mRNA
CTD
PMID:14563831
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acadm
acyl-CoA dehydrogenase medium chain
increases expression
EXP
Linoleic Acid results in increased expression of ACADM mRNA
CTD
PMID:23056435
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acly
ATP citrate lyase
decreases expression
EXP
Linoleic Acid results in decreased expression of ACLY mRNA
CTD
PMID:14563831
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acmsd
aminocarboxymuconate semialdehyde decarboxylase
decreases expression
EXP
Linoleic Acid results in decreased expression of ACMSD mRNA
CTD
PMID:18320257
NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209
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Acox1
acyl-CoA oxidase 1
increases expression
EXP
Linoleic Acid results in increased expression of ACOX1 mRNA
CTD
PMID:18320257
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Adipoq
adiponectin, C1Q and collagen domain containing
decreases expression
ISO
Linoleic Acid results in decreased expression of ADIPOQ mRNA
CTD
PMID:17374693
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adipor1
adiponectin receptor 1
increases expression
ISO
Linoleic Acid analog results in increased expression of ADIPOR1 mRNA
CTD
PMID:27939595
NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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Ager
advanced glycosylation end product-specific receptor
multiple interactions
EXP
AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]
CTD
PMID:22467055
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Ahr
aryl hydrocarbon receptor
multiple interactions
ISO
Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]
CTD
PMID:18001219
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Alox15
arachidonate 15-lipoxygenase
increases oxidation
ISO
ALOX15 protein results in increased oxidation of Linoleic Acid
CTD
PMID:25786526
NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
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Apoa1
apolipoprotein A1
multiple interactions
ISO
Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]
CTD
PMID:16118212
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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App
amyloid beta precursor protein
multiple interactions
ISO
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Linoleic Acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Linoleic Acid]
CTD
PMID:39172838
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Ascl2
achaete-scute family bHLH transcription factor 2
decreases expression
ISO
Linoleic Acid results in decreased expression of ASCL2 mRNA
CTD
PMID:15708366
NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406
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Bche
butyrylcholinesterase
increases expression
ISO
Linoleic Acid results in increased expression of BCHE mRNA
CTD
PMID:27106529
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of BCL2 protein]
CTD
PMID:22467055
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Cat
catalase
increases expression multiple interactions
ISO EXP
Linoleic Acid results in increased expression of CAT protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased activity of CAT protein]
CTD
PMID:10946007 PMID:34111468
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccl2
C-C motif chemokine ligand 2
increases expression
ISO
Linoleic Acid results in increased expression of CCL2 protein
CTD
PMID:16305726
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Cd36
CD36 molecule
multiple interactions
EXP
[Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA
CTD
PMID:28552552
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Chrna7
cholinergic receptor nicotinic alpha 7 subunit
multiple interactions
EXP
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of CHRNA7 mRNA]
CTD
PMID:34111468
NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
G
Cnr1
cannabinoid receptor 1
multiple interactions affects response to substance
ISO
CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein] CNR1 protein affects the susceptibility to Linoleic Acid
CTD
PMID:30241419
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Col1a1
collagen type I alpha 1 chain
increases expression
ISO
Linoleic Acid results in increased expression of COL1A1 mRNA
CTD
PMID:26240151
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col3a1
collagen type III alpha 1 chain
decreases expression
ISO
Linoleic Acid results in decreased expression of COL3A1 mRNA
CTD
PMID:26240151
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression
EXP
Linoleic Acid results in increased expression of CPT1A mRNA
CTD
PMID:11171094
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Crebbp
CREB binding protein
multiple interactions
ISO
Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]
CTD
PMID:19263263
NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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Cycs
cytochrome c, somatic
multiple interactions
ISO
[Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein
CTD
PMID:27016407
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]
CTD
PMID:18001219
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity
ISO
Linoleic Acid results in decreased activity of CYP1A2 protein
CTD
PMID:16978661
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
multiple interactions decreases activity
ISO
CYP2C19 protein results in increased metabolism of [Linoleic Acid co-treated with NADP] Linoleic Acid results in decreased activity of CYP2C19 protein
CTD
PMID:16978661
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases activity
ISO
Linoleic Acid results in decreased activity of CYP2E1 protein
CTD
PMID:16978661
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
decreases activity
ISO
Linoleic Acid results in decreased activity of CYP3A4 protein
CTD
PMID:16978661
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Linoleic Acid analog results in increased expression of DDIT3 protein
CTD
PMID:27939595
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Dio1
iodothyronine deiodinase 1
decreases activity
ISO
Linoleic Acid results in decreased activity of DIO1 protein
CTD
PMID:30561685
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
G
Dio2
iodothyronine deiodinase 2
decreases activity
ISO
Linoleic Acid results in decreased activity of DIO2 protein
CTD
PMID:30561685
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
G
Dio3
iodothyronine deiodinase 3
decreases activity
ISO
Linoleic Acid results in decreased activity of DIO3 protein
CTD
PMID:30561685
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
G
Edn1
endothelin 1
decreases expression
ISO
Linoleic Acid results in decreased expression of EDN1 mRNA; Linoleic Acid results in decreased expression of EDN1 protein
CTD
PMID:16895544
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Fabp1
fatty acid binding protein 1
decreases expression
ISO
Linoleic Acid results in decreased expression of FABP1 mRNA
CTD
PMID:15708366
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
G
Fabp3
fatty acid binding protein 3
decreases expression
ISO
Linoleic Acid results in decreased expression of FABP3 mRNA
CTD
PMID:15708366
NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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Fabp4
fatty acid binding protein 4
affects localization
ISO
Linoleic Acid analog affects the localization of FABP4 protein
CTD
PMID:27939595
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fads2
fatty acid desaturase 2
multiple interactions increases expression
ISO
[Linoleic Acid co-treated with Testosterone] results in increased expression of FADS2 mRNA FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein] Linoleic Acid results in increased expression of FADS2 mRNA; Linoleic Acid results in increased expression of FADS2 protein
CTD
PMID:21457203 PMID:26240151
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fasn
fatty acid synthase
decreases expression
EXP
Linoleic Acid results in decreased expression of FASN mRNA
CTD
PMID:14563831
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Ffar3
free fatty acid receptor 3
increases expression
ISO
Linoleic Acid analog results in increased expression of FFAR3 mRNA
CTD
PMID:27939595
NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
G
Foxo1
forkhead box O1
decreases expression
ISO
Linoleic Acid results in decreased expression of FOXO1 protein
CTD
PMID:17374693
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Gcg
glucagon
multiple interactions
ISO
CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein]
CTD
PMID:30241419
NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Linoleic Acid metabolite results in increased expression of GCLM mRNA
CTD
PMID:26879219
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Gjb1
gap junction protein, beta 1
increases abundance
ISO
GJB1 protein results in increased abundance of Linoleic Acid
CTD
PMID:27859493
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
multiple interactions
EXP
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2A mRNA]
CTD
PMID:34111468
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
multiple interactions
EXP
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2B mRNA]
CTD
PMID:34111468
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Gsta1
glutathione S-transferase alpha 1
increases expression multiple interactions
ISO
Linoleic Acid results in increased expression of GSTA1 mRNA NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA]
CTD
PMID:28555106
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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Havcr1
hepatitis A virus cellular receptor 1
increases secretion
ISO
Linoleic Acid results in increased secretion of HAVCR1 protein
CTD
PMID:31686351
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA] Linoleic Acid metabolite results in increased expression of HMOX1 mRNA; Linoleic Acid metabolite results in increased expression of HMOX1 protein
CTD
PMID:26879219
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa5
heat shock protein family A (Hsp70) member 5
increases expression
ISO
Linoleic Acid analog results in increased expression of HSPA5 protein
CTD
PMID:27939595
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Ifng
interferon gamma
increases expression
ISO
Linoleic Acid results in increased expression of IFNG protein
CTD
PMID:16305726
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il10
interleukin 10
increases expression
ISO
Linoleic Acid results in increased expression of IL10 protein
CTD
PMID:16305726
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1b
interleukin 1 beta
increases expression multiple interactions
ISO EXP
Linoleic Acid results in increased expression of IL1B protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL1B mRNA]
CTD
PMID:16305726 PMID:34111468
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il2
interleukin 2
decreases expression
ISO
Linoleic Acid results in decreased expression of IL2 protein
CTD
PMID:16305726
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il4
interleukin 4
decreases expression
ISO
Linoleic Acid results in decreased expression of IL4 protein
CTD
PMID:16305726
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il5
interleukin 5
decreases expression
ISO
Linoleic Acid results in decreased expression of IL5 protein
CTD
PMID:16305726
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Il6
interleukin 6
affects expression multiple interactions increases expression increases secretion
ISO EXP
Linoleic Acid affects the expression of IL6 protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL6 mRNA] Linoleic Acid results in increased expression of IL6 mRNA Linoleic Acid results in increased secretion of IL6 protein
CTD
PMID:16305726 PMID:17374693 PMID:21457203 PMID:34111468
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Insr
insulin receptor
increases expression
ISO
Linoleic Acid analog results in increased expression of INSR mRNA
CTD
PMID:27939595
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
G
Iyd
iodotyrosine deiodinase
multiple interactions
ISO
Linoleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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Lcat
lecithin cholesterol acyltransferase
increases expression
ISO
Linoleic Acid analog results in increased expression of LCAT mRNA
CTD
PMID:27939595
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Lipc
lipase C, hepatic type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid
CTD
PMID:24777581
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipg
lipase G, endothelial type
multiple interactions
ISO
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid
CTD
PMID:24777581
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
G
Lox
lysyl oxidase
multiple interactions increases activity
ISO
FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein]; TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein]
CTD
PMID:26240151
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Lpin1
lipin 1
decreases expression
ISO
Linoleic Acid analog results in decreased expression of LPIN1 mRNA
CTD
PMID:27939595
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
G
Lrat
lecithin retinol acyltransferase
increases expression
EXP
Linoleic Acid results in increased expression of LRAT mRNA
CTD
PMID:12576510
NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD
PMID:23288142
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mmp9
matrix metallopeptidase 9
multiple interactions decreases expression
ISO EXP
Linoleic Acid results in decreased expression of and results in decreased activity of MMP9 protein [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of MMP9 protein] Linoleic Acid results in decreased expression of MMP9 mRNA
CTD
PMID:22467055 PMID:23288142
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Ncf1
neutrophil cytosolic factor 1
multiple interactions
ISO
Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF1 protein]
CTD
PMID:12101222
NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
G
Ncf2
neutrophil cytosolic factor 2
multiple interactions
ISO
Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein]
CTD
PMID:12101222
NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
G
Ncoa1
nuclear receptor coactivator 1
multiple interactions
ISO
Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein]
CTD
PMID:19263263
NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664
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Ncoa2
nuclear receptor coactivator 2
multiple interactions
ISO
Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein]
CTD
PMID:19263263
NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression multiple interactions
ISO
Linoleic Acid metabolite results in increased expression of NFE2L2 protein; Linoleic Acid results in increased expression of NFE2L2 mRNA; Linoleic Acid results in increased expression of NFE2L2 protein NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 protein]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA]
CTD
PMID:26879219 PMID:28555106
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
EXP
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of NFKB1 mRNA]
CTD
PMID:34111468
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
G
Nos2
nitric oxide synthase 2
multiple interactions
EXP
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of NOS2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of NOS2 protein]
CTD
PMID:22467055
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
decreases expression
ISO
Linoleic Acid results in decreased expression of NOS3 mRNA
CTD
PMID:16895544
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
Linoleic Acid metabolite results in increased expression of NQO1 mRNA
CTD
PMID:26879219
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr5a2
nuclear receptor subfamily 5, group A, member 2
multiple interactions
ISO
[NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Linoleic Acid analog
CTD
PMID:29515023
NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326
G
Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
ISO
[Glucose deficiency co-treated with Linoleic Acid] results in increased expression of PCK1 mRNA
CTD
PMID:8536680
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pdk4
pyruvate dehydrogenase kinase 4
increases expression
EXP
Linoleic Acid results in increased expression of PDK4 mRNA
CTD
PMID:23056435
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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Pld2
phospholipase D2
multiple interactions
ISO
PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]
CTD
PMID:16118212
NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
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Plin1
perilipin 1
increases expression
ISO
Linoleic Acid analog results in increased expression of PLIN1 mRNA
CTD
PMID:27939595
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
G
Pon1
paraoxonase 1
multiple interactions decreases activity
ISO
Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid] Linoleic Acid results in decreased activity of PON1 protein
CTD
PMID:12871208 PMID:15375178
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions increases expression affects abundance increases activity affects binding
ISO EXP
[Bezafibrate binds to and results in increased activity of PPARA protein] which results in increased oxidation of Linoleic Acid; Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]; Linoleic Acid binds to and results in increased activity of PPARA protein; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein]; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] Linoleic Acid results in increased expression of PPARA mRNA PPARA protein affects the abundance of Linoleic Acid Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Linoleic Acid]; Linoleic Acid binds to and results in increased activity of PPARA protein Linoleic Acid results in increased expression of PPARA mRNA; Linoleic Acid results in increased expression of PPARA protein Linoleic Acid results in increased activity of PPARA protein Linoleic Acid binds to PPARA protein
CTD
PMID:10403814 PMID:11172467 PMID:15491415 PMID:16731579 PMID:18154422 PMID:19263263 PMID:20404010 PMID:23056435 PMID:23619606 PMID:23843199 PMID:25786526 PMID:35752307 More...
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Ppard
peroxisome proliferator-activated receptor delta
multiple interactions decreases expression increases expression increases activity affects binding
ISO EXP
Linoleic Acid binds to and results in increased activity of PPARB protein Linoleic Acid results in decreased expression of PPARD mRNA Linoleic Acid results in increased expression of PPARD mRNA Linoleic Acid results in increased activity of PPARD protein Linoleic Acid binds to PPARB protein
CTD
PMID:11172467 PMID:15708366 PMID:16731579 PMID:23843199 PMID:25786526
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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Pparg
peroxisome proliferator-activated receptor gamma
affects binding multiple interactions increases expression increases activity decreases expression
ISO EXP
Linoleic Acid binds to PPARG protein Linoleic Acid binds to and results in increased activity of PPARG protein Linoleic Acid results in increased expression of PPARG mRNA resveratrol inhibits the reaction [Linoleic Acid results in increased expression of PPARG protein] Linoleic Acid results in increased activity of PPARG protein Linoleic Acid results in decreased expression of PPARG mRNA; Linoleic Acid results in decreased expression of PPARG protein
CTD
PMID:11172467 PMID:12021203 PMID:15708366 PMID:16731579 PMID:18154422 PMID:23843199 PMID:25672876 PMID:25786526 PMID:35752307 More...
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
EXP ISO
Linoleic Acid results in increased expression of PPARGC1A mRNA
CTD
PMID:23056435
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Ppargc1b
PPARG coactivator 1 beta
increases expression
EXP
Linoleic Acid results in increased expression of PPARGC1B mRNA
CTD
PMID:23056435
NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
G
Psen1
presenilin 1
multiple interactions
ISO
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Linoleic Acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Linoleic Acid]
CTD
PMID:39172838
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression multiple interactions
EXP ISO
Linoleic Acid results in increased expression of PTGS2 mRNA Linoleic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD
PMID:14563831 PMID:18001219
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Rxra
retinoid X receptor alpha
affects binding multiple interactions
ISO
Linoleic Acid binds to RXRA protein Linoleic Acid binds to and results in increased activity of RXRA protein
CTD
PMID:16258897 PMID:16731579
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
G
Scd
stearoyl-CoA desaturase
multiple interactions increases expression
ISO
[Linoleic Acid co-treated with Testosterone] results in increased expression of SCD mRNA Linoleic Acid results in increased expression of SCD mRNA; Linoleic Acid results in increased expression of SCD protein
CTD
PMID:21457203
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Serpine1
serpin family E member 1
increases expression
ISO
Linoleic Acid results in increased expression of SERPINE1 mRNA
CTD
PMID:17374693
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Slc22a6
solute carrier family 22 member 6
decreases activity
ISO
Linoleic Acid results in decreased activity of SLC22A6 protein
CTD
PMID:29045746
NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
G
Slc22a8
solute carrier family 22 member 8
decreases activity
ISO
Linoleic Acid results in decreased activity of SLC22A8 protein
CTD
PMID:29045746
NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Smad3
SMAD family member 3
decreases abundance
ISO
SMAD3 protein results in decreased abundance of Linoleic Acid
CTD
PMID:23034213
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
G
Srebf1
sterol regulatory element binding transcription factor 1
decreases expression
EXP
Linoleic Acid results in decreased expression of SREBF1 mRNA
CTD
PMID:14563831
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
G
Tgfb1
transforming growth factor, beta 1
multiple interactions
ISO
TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein]
CTD
PMID:26240151
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Tnf
tumor necrosis factor
decreases response to substance multiple interactions
ISO EXP
Linoleic Acid results in decreased susceptibility to TNF protein Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of TNF mRNA]
CTD
PMID:22683933 PMID:34111468
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
ISO
TRPV1 results in increased susceptibility to [Linoleic Acid co-treated with Freund's Adjuvant]
CTD
PMID:23006841
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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Ucp2
uncoupling protein 2
increases expression
EXP
Linoleic Acid results in increased expression of UCP2 mRNA
CTD
PMID:11341955
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
G
Vegfa
vascular endothelial growth factor A
multiple interactions
EXP
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of VEGFA protein]
CTD
PMID:22467055
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Wnt10b
Wnt family member 10B
decreases expression
ISO
Linoleic Acid results in decreased expression of WNT10B mRNA
CTD
PMID:12021203
NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
G
Agt
angiotensinogen
multiple interactions increases lipidation
ISO
Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]
CTD
PMID:26111765
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
G
Cygb
cytoglobin
increases metabolic processing
EXP
CYGB protein results in increased metabolism of linoleic acid hydroperoxide
CTD
PMID:11320098
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
G
Gpx1
glutathione peroxidase 1
increases reduction
ISO
GPX1 protein results in increased reduction of linoleic acid hydroperoxide
CTD
PMID:8428933
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx2
glutathione peroxidase 2
increases reduction
ISO
GPX2 protein results in increased reduction of linoleic acid hydroperoxide
CTD
PMID:8428933
NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
G
Iyd
iodotyrosine deiodinase
multiple interactions
ISO
methyl linoleate inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine]
CTD
PMID:33352258
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
G
Abcb11
ATP binding cassette subfamily B member 11
affects expression
EXP
Soybean Oil affects the expression of ABCB11 mRNA
CTD
PMID:15770074
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
G
Abcb1b
ATP-binding cassette, sub-family B member 1B
affects expression
EXP
Soybean Oil affects the expression of ABCB1B mRNA
CTD
PMID:15770074
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
G
Abcb4
ATP binding cassette subfamily B member 4
affects expression
EXP
Soybean Oil affects the expression of ABCB4 mRNA
CTD
PMID:15770074
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
G
Abcc1
ATP binding cassette subfamily C member 1
affects expression
EXP
Soybean Oil affects the expression of ABCC1 mRNA
CTD
PMID:15770074
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Abcc2
ATP binding cassette subfamily C member 2
affects expression
EXP
Soybean Oil affects the expression of ABCC2 mRNA
CTD
PMID:15770074
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abcc5
ATP binding cassette subfamily C member 5
affects expression
EXP
Soybean Oil affects the expression of ABCC5 mRNA
CTD
PMID:15770074
NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
G
Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Soybean Oil affects the expression of ABCC6 mRNA
CTD
PMID:15770074
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
G
Acat1
acetyl-CoA acetyltransferase 1
decreases activity
EXP
Soybean Oil results in decreased activity of ACAT1 protein
CTD
PMID:12559476
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
G
Bcl2
BCL2, apoptosis regulator
increases expression
EXP
Soybean Oil results in increased expression of BCL2 protein
CTD
PMID:15309441
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Cat
catalase
increases activity
EXP
Soybean Oil results in increased activity of CAT protein
CTD
PMID:12781854
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Ccnd1
cyclin D1
increases expression
EXP
Soybean Oil results in increased expression of CCND1 mRNA
CTD
PMID:21088903
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
affects expression
EXP
Soybean Oil affects the expression of CYP4A1 mRNA
CTD
PMID:16079505
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
G
Cyp7a1
cytochrome P450 family 7 subfamily A member 1
increases activity
EXP
Soybean Oil results in increased activity of CYP7A1 protein
CTD
PMID:12559476
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein]
CTD
PMID:11600134
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases activity
EXP
Soybean Oil results in increased activity of HMGCR protein
CTD
PMID:12559476
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Il12b
interleukin 12B
decreases expression
ISO
Soybean Oil results in decreased expression of IL12B mRNA
CTD
PMID:10065739
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
G
Slc22a1
solute carrier family 22 member 1
affects expression
EXP
Soybean Oil affects the expression of SLC22A1 mRNA
CTD
PMID:15770074
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
G
Slc22a7
solute carrier family 22 member 7
affects expression
EXP
Soybean Oil affects the expression of SLC22A7 mRNA
CTD
PMID:15770074
NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19917
chemical entity
19915
atom
19915
nonmetal atom
19838
carbon atom
19790
organic molecular entity
19790
lipid
17994
fatty acid
16846
long-chain fatty acid
3472
octadecanoid
316
(10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid
0
(6E,8Z)-5-oxooctadecadienoic acid
0
(9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid
0
11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid
0
12,13-DiHODE
0
12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid
0
15,16-DiHODE
0
5(S),8(R)-DiHODE
0
7(S),8(S)-DiHODE
0
7-hydroxycoumarinyl-gamma-linolenate
0
8(R)-HPODE
0
9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid
0
HODE +
3
HPODE +
11
Jasmonate derivatives +
0
Oxo-dihydroxy-octadecadienoic acid
0
Oxo-octadecadienoic acid
0
Porrigenic acid
0
TriHOME +
1
hydroperoxyoctadecatrienoic acid +
0
hydroperoxyoctadecenoic acid +
0
octadecadienoic acid +
315
octadecatetraenoic acid +
0
Path 2
CHEBI ontology
19917
subatomic particle
19915
composite particle
19915
hadron
19915
baryon
19915
nucleon
19915
atomic nucleus
19915
atom
19915
main group element atom
19855
p-block element atom
19855
carbon group element atom
19794
carbon atom
19790
organic molecular entity
19790
heteroorganic entity
19548
organochalcogen compound
19307
organooxygen compound
19223
carbon oxoacid
18687
carboxylic acid
18684
monocarboxylic acid
18024
fatty acid
16846
long-chain fatty acid
3472
octadecanoid
316
(10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid
0
(6E,8Z)-5-oxooctadecadienoic acid
0
(9Z,11Z,13S,15Z)-12,13-epoxyoctadecatrienoic acid
0
11-hydroxy-(12S,13S)-epoxy-(9Z)-octadecenoic acid
0
12,13-DiHODE
0
12,13-epoxy-18-hydroxy-(9Z)-octadecenoic acid
0
15,16-DiHODE
0
5(S),8(R)-DiHODE
0
7(S),8(S)-DiHODE
0
7-hydroxycoumarinyl-gamma-linolenate
0
8(R)-HPODE
0
9,10-epoxy-18-hydroxy-(12Z)-octadecenoic acid
0
HODE +
3
HPODE +
11
Jasmonate derivatives +
0
Oxo-dihydroxy-octadecadienoic acid
0
Oxo-octadecadienoic acid
0
Porrigenic acid
0
TriHOME +
1
hydroperoxyoctadecatrienoic acid +
0
hydroperoxyoctadecenoic acid +
0
octadecadienoic acid +
315
octadecatetraenoic acid +
0