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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hepoxilin A3
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Accession:CHEBI:36190 term browser browse the term
Definition:A hepoxilin having (5Z,9E,14Z) double bond stereochemistry, an 8-hydroxy substituent and an 11S,12S-epoxy group.
Synonyms:exact_synonym: (5Z,9E)-8-hydroxy-10-{(2S,3S)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,9-dienoic acid
 related_synonym: (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyeicosa-5,9,14-trienoic acid;   (5Z,9E,14Z)-(11S,12S)-11,12-Epoxy-8-hydroxyicosa-5,9,14-trienoic acid;   8-EH-2;   8-Hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid;   8-hydroxy-10-(3-(2-octenyl)oxiranyl)-5,9-decadienoic acid;   8-hydroxy-11(S),12(S)-epoxy-eicosa- 5Z,9E,14Z-trienoic acid;   8-hydroxy-11S,12S-epoxy-5Z,14Z,9E-eicosatrienoic acid;   Formula=C20H32O4;   HXA3;   Hepoxilin A;   InChI=1S/C20H32O4/c1-2-3-4-5-6-10-13-18-19(24-18)16-15-17(21)12-9-7-8-11-14-20(22)23/h6-7,9-10,15-19,21H,2-5,8,11-14H2,1H3,(H,22,23)/b9-7-,10-6-,16-15+/t17?,18-,19-/m0/s1;   InChIKey=SGTUOBURCVMACZ-SEVPPISGSA-N;   SMILES=[H][C@@]1(C\\C=C/CCCCC)O[C@@]1([H])\\C=C\\C(O)C\\C=C/CCCC(O)=O
 alt_id: CHEBI:34783;   CHEBI:5670
 xref: CAS:85589-24-8;   CAS:94161-11-2;   KEGG:C14808;   LIPID_MAPS_instance:LMFA03090005
 xref_mesh: MESH:C038243
 xref: PMID:10100848;   PMID:10644052;   PMID:15123652;   PMID:8573089;   Reaxys:21024403
 cyclic_relationship: is_conjugate_acid_of CHEBI:132127


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hepoxilin A3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases export ISO ABCC2 protein results in increased export of 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid CTD PMID:30102254 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            xenobiotic metabolite 16158
              human xenobiotic metabolite 15778
                hepoxilin A3 1
                  (8S)-hepoxilin A3 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18000
                                        fatty acid 16833
                                          unsaturated fatty acid 1684
                                            polyunsaturated fatty acid 847
                                              trienoic fatty acid 268
                                                fatty acid 20:3 1
                                                  (5Z,9E,14Z)-icosa-5,9,14-trienoic acid 1
                                                    hepoxilin A3 1
                                                      (8S)-hepoxilin A3 0
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