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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlordiazepoxide
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Accession:CHEBI:3611 term browser browse the term
Definition:A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.
Synonyms:exact_synonym: 7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide
 related_synonym: 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide;   CDP;   Formula=C16H14ClN3O;   Helogaphen;   InChI=1S/C16H14ClN3O/c1-18-15-10-20(21)16(11-5-3-2-4-6-11)13-9-12(17)7-8-14(13)19-15/h2-9H,10H2,1H3,(H,18,19);   InChIKey=ANTSCNMPPGJYLG-UHFFFAOYSA-N;   Libritabs;   Multum;   Risolid;   SMILES=CNC1=Nc2ccc(Cl)cc2C(c2ccccc2)=N(=O)C1;   Silibrin;   Tropium;   chlordiazepoxide base;   chlordiazepoxidum;   clopoxide;   methaminodiazepoxide
 xref: CAS:58-25-3;   DrugBank:DB00475;   Drug_Central:594;   HMDB:HMDB0014618;   KEGG:D00267
 xref_mesh: MESH:D002707
 xref: PMID:17049372;   PMID:19643124;   PMID:9632243;   Patent:MY6500040;   Patent:US2893992;   Patent:US3122474;   Reaxys:550356;   Wikipedia:Chlordiazepoxide



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chlordiazepoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Chlordiazepoxide results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon decreases response to substance EXP GABRE protein results in decreased susceptibility to Chlordiazepoxide CTD PMID:11691872 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions EXP Chlordiazepoxide inhibits the reaction [TRH protein modified form binds to TRHR protein] CTD PMID:2845442 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          adjuvant 4836
            anaesthesia adjuvant 301
              chlordiazepoxide 4
                chlordiazepoxide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            inorganic hydride 18161
                              pnictogen hydride 18151
                                nitrogen hydride 18064
                                  azane 17872
                                    ammonia 17871
                                      organic amino compound 17871
                                        secondary amino compound 6954
                                          chlordiazepoxide 4
                                            chlordiazepoxide hydrochloride 0
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