The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.
[1-hydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [1-hydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA
1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]
1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL6 mRNA]; 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]
1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]
1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]; 1-hydroxy-2-naphthoic acid analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]
browse the term
