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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trans-stilbene
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Accession:CHEBI:36007 term browser browse the term
Definition:The trans-isomer of stilbene.
Synonyms:exact_synonym: 1,1'-[(1E)-ethene-1,2-diyl]dibenzene
 related_synonym: (E)-1,2-diphenylethylene;   (E)-stilbene;   1,1'-(E)-ethene-1,2-diyldibenzene;   Formula=C14H12;   InChI=1S/C14H12/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-12H/b12-11+;   InChIKey=PJANXHGTPQOBST-VAWYXSNFSA-N;   SMILES=c1ccc(cc1)\\C=C\\c1ccccc1;   [(E)-2-phenylethenyl]benzene;   trans-1,2-diphenylethylene;   trans-alpha,beta-diphenylethylene
 xref: Beilstein:1616740;   CAS:103-30-0;   Gmelin:4381;   KNApSAcK:C00037932;   PMID:32201774;   PMID:32662469;   PMID:33564098;   Wikipedia:(E)-Stilbene


show annotations for term's descendants           Sort by:
isorhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Hydrogen Peroxide]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO isorhapontigenin results in decreased expression of CCND1 protein CTD PMID:37619952 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased expression of CDH1 protein CTD PMID:37619952 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased localization of CTNNB1 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased phosphorylation of CTNNB1 protein CTD PMID:37619952 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3A protein CTD PMID:37619952 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dnmt3b DNA methyltransferase 3B multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3B protein CTD PMID:37619952 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Fos FBJ osteosarcoma oncogene affects expression ISO isorhapontigenin affects the expression of FOS protein CTD PMID:15607907 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta affects activity ISO isorhapontigenin affects the activity of IKBKB protein CTD PMID:15607907 NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Jun jun proto-oncogene affects expression ISO isorhapontigenin affects the expression of JUN protein CTD PMID:15607907 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:15607907 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:15607907 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Meg3 maternally expressed 3 multiple interactions ISO isorhapontigenin inhibits the reaction [sodium bichromate results in decreased expression of MEG3] CTD PMID:37619952 NCBI chr12:109,506,879...109,538,163
Ensembl chr12:109,506,877...109,538,165 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression ISO isorhapontigenin results in decreased expression of MKI67 protein CTD PMID:37619952 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of and results in decreased localization of NEDD9 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of NEDD9 mRNA CTD PMID:37619952 NCBI chr13:41,463,392...41,640,836
Ensembl chr13:41,463,057...41,640,838 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO isorhapontigenin affects the degradation of and affects the phosphorylation of NFKBIA protein CTD PMID:15607907 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Snai2 snail family zinc finger 2 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of SNAI2 protein CTD PMID:37619952 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
pterostilbene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions EXP pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain increases expression ISO pterostilbene results in increased expression of ACADM mRNA CTD PMID:26443543 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269 		JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of ACOX1 protein CTD PMID:25083823 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871 		JBrowse link
G Ahr aryl-hydrocarbon receptor increases activity
multiple interactions		 ISO pterostilbene results in increased activity of AHR protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased activity of AHR protein]; pterostilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]		 CTD PMID:28279696 PMID:31004704 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions EXP pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 protein] CTD PMID:21355597 NCBI chr 6:34,280,865...34,294,424
Ensembl chr 6:34,279,369...34,294,413 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases expression
increases phosphorylation
multiple interactions		 ISO pterostilbene results in decreased expression of AKT1 mRNA
pterostilbene results in increased phosphorylation of AKT1 protein
pterostilbene results in decreased phosphorylation of and results in decreased activity of AKT1 protein		 CTD PMID:20152895 PMID:24154491 PMID:31139082 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO pterostilbene results in decreased expression of AMACR mRNA CTD PMID:20152895 NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form] CTD PMID:19549798 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983 		JBrowse link
G Atg5 autophagy related 5 multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]] CTD PMID:34405320 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]] CTD PMID:34405320 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions		 EXP
ISO		 pterostilbene results in increased expression of BAD protein
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAD protein]		 CTD PMID:20681671 PMID:31139082 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO pterostilbene results in increased expression of BAK1 protein CTD PMID:23313376 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Bax BCL2-associated X protein affects response to substance
increases expression
multiple interactions		 ISO
EXP		 BAX protein affects the susceptibility to pterostilbene
pterostilbene results in increased expression of BAX protein
pterostilbene results in increased expression of BAX mRNA; pterostilbene results in increased expression of BAX protein
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAX protein]		 CTD PMID:20152895 PMID:20681671 PMID:22572619 PMID:23313376 PMID:24936659 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
increases expression
decreases expression		 ISO
EXP		 [pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein; pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene results in increased expression of BCL2 protein
pterostilbene results in decreased expression of BCL2 mRNA; pterostilbene results in decreased expression of BCL2 protein		 CTD PMID:18852136 PMID:20152895 PMID:20681671 PMID:24936659 PMID:31139082 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 pterostilbene results in increased expression of BCL2L1 protein
pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2L1 protein]
pterostilbene results in decreased expression of BCL2L1 protein		 CTD PMID:20681671 PMID:23313376 PMID:31139082 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO
EXP		 BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]] CTD PMID:34405320 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP pterostilbene results in increased expression of BID protein modified form CTD PMID:20681671 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions
increases expression		 ISO calcipotriene promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP protein]; paricalcitol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP protein]
pterostilbene results in increased expression of CAMP mRNA; pterostilbene results in increased expression of CAMP protein		 CTD PMID:24039193 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]] CTD PMID:34474091 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
increases expression		 EXP
ISO		 pterostilbene results in increased cleavage of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP3 protein]; pterostilbene inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]
pterostilbene results in increased expression of CASP3 mRNA		 CTD PMID:20152895 PMID:20681671 PMID:23313376 PMID:24936659 PMID:25341683 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase multiple interactions
increases activity		 ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP7 protein] CTD PMID:33930484 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G Casp8 caspase 8 multiple interactions EXP pterostilbene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:20681671 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
increases cleavage		 ISO
EXP		 pterostilbene results in increased expression of CASP9 protein
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein]
pterostilbene results in increased cleavage of CASP9 protein		 CTD PMID:20152895 PMID:20681671 PMID:25341683 PMID:33930484 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cat catalase multiple interactions
increases expression		 ISO
EXP		 CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]
pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]
pterostilbene results in increased expression of CAT mRNA		 CTD PMID:25341683 PMID:26700463 PMID:34474091 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions EXP
ISO		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]
3-methyladenine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; Ammonium Chloride inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; Chloroquine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]		 CTD PMID:34405320 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO
EXP		 pterostilbene results in decreased expression of CCND1 protein
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 protein]		 CTD PMID:19549798 PMID:20398797 PMID:20681671 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO pterostilbene results in decreased expression of CCNE1 protein CTD PMID:20398797 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression		 EXP
ISO		 pterostilbene inhibits the reaction [Azoxymethane results in decreased expression of CDH1 protein]
pterostilbene results in increased expression of CDH1 protein		 CTD PMID:20681671 PMID:23921149 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO pterostilbene results in decreased expression of CDK2 protein CTD PMID:20398797 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO pterostilbene results in decreased expression of CDK4 protein CTD PMID:20398797 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO
EXP		 pterostilbene results in increased expression of CDKN1A protein
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]		 CTD PMID:23313376 PMID:34405320 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO pterostilbene results in increased expression of CDKN1B protein CTD PMID:23313376 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A multiple interactions ISO
EXP		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]] CTD PMID:34405320 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of CPT1A protein CTD PMID:25083823 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions ISO [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression		 ISO pterostilbene affects the localization of CYCS protein
pterostilbene results in increased expression of CYCS mRNA; pterostilbene results in increased expression of CYCS protein		 CTD PMID:22450950 PMID:22572619 PMID:26443543 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions		 ISO pterostilbene results in decreased expression of CYP1A1 mRNA
pterostilbene results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased expression of CYP1A1 protein]		 CTD PMID:22450950 PMID:31004704 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP
ISO		 pterostilbene results in decreased activity of CYP1A2 protein CTD PMID:16684708 PMID:30394306 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression ISO pterostilbene results in increased expression of CYP2B6 mRNA CTD PMID:30394306 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity ISO pterostilbene results in decreased activity of CYP2C19 protein CTD PMID:30394306 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]
pterostilbene results in increased expression of DDIT3 mRNA; pterostilbene results in increased expression of DDIT3 protein		 CTD PMID:22450950 PMID:25341683 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dffa DNA fragmentation factor, alpha subunit increases cleavage EXP pterostilbene results in increased cleavage of DFFA protein CTD PMID:20681671 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104 		JBrowse link
G Dhrs2 dehydrogenase/reductase member 2 increases expression ISO pterostilbene results in increased expression of DHRS2 mRNA; pterostilbene results in increased expression of DHRS2 protein CTD PMID:24936659 NCBI chr14:55,459,464...55,478,897
Ensembl chr14:55,459,464...55,478,892 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
affects localization		 ISO pterostilbene results in increased expression of DIABLO protein
pterostilbene affects the localization of DIABLO protein		 CTD PMID:22450950 PMID:22572619 NCBI chr 5:123,649,393...123,664,825
Ensembl chr 5:123,647,828...123,662,239 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT1 mRNA CTD PMID:26459286 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184 		JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT3A mRNA CTD PMID:26459286 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443 		JBrowse link
G Dnmt3b DNA methyltransferase 3B multiple interactions ISO pterostilbene promotes the reaction [resveratrol results in decreased expression of DNMT3B mRNA] CTD PMID:26459286 NCBI chr 2:153,491,332...153,529,650
Ensembl chr 2:153,491,370...153,529,650 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] CTD PMID:19447859 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO pterostilbene results in increased phosphorylation of EIF2A protein CTD PMID:25341683 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229 		JBrowse link
G Elk1 ELK1, member of ETS oncogene family multiple interactions ISO pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form] CTD PMID:19549798 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) increases expression
multiple interactions		 ISO pterostilbene results in increased expression of ESR1 protein
[resveratrol co-treated with pterostilbene] results in increased expression of ESR1 mRNA; [resveratrol co-treated with pterostilbene] results in increased expression of ESR1 protein		 CTD PMID:27159275 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions EXP ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein] CTD PMID:24361291 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP pterostilbene results in increased expression of FAS protein CTD PMID:20681671 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fasl Fas ligand increases expression EXP pterostilbene results in increased expression of FASL protein CTD PMID:20681671 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein CTD PMID:25083823 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein] CTD PMID:18551458 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Fut1 fucosyltransferase 1 increases expression ISO pterostilbene results in increased expression of FUT1 mRNA CTD PMID:22450950 NCBI chr 7:45,266,862...45,270,483
Ensembl chr 7:45,266,713...45,270,483 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO pterostilbene results in increased expression of GDF15 mRNA CTD PMID:22450950 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein] CTD PMID:33930484 NCBI chr17:30,811,835...30,831,633
Ensembl chr17:30,803,910...30,845,845 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA] CTD PMID:25341683 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein] CTD PMID:20681671 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gsr glutathione reductase multiple interactions
decreases expression		 EXP
ISO		 NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]
pterostilbene results in decreased expression of GSR mRNA		 CTD PMID:21355597 PMID:25341683 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO
EXP		 [Resveratrol co-treated with pterostilbene] results in decreased expression of H2AX protein modified form; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]] CTD PMID:26459286 PMID:34405320 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions
increases phosphorylation		 ISO HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter] CTD PMID:26443543 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992 		JBrowse link
G Hmga1 high mobility group AT-hook 1 multiple interactions ISO
EXP		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of HMGA1 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]		 CTD PMID:34405320 PMID:34474091 NCBI chr17:27,774,798...27,782,649
Ensembl chr17:27,775,471...27,782,648 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]] CTD PMID:34474091 NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO
EXP		 pterostilbene results in increased expression of HMOX1 mRNA; pterostilbene results in increased expression of HMOX1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of HMOX1 mRNA; pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 mRNA]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]
NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 protein]		 CTD PMID:21355597 PMID:22450950 PMID:25111660 PMID:31139082 PMID:33930484 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M increases expression ISO pterostilbene results in increased expression of HNRNPM mRNA CTD PMID:22450950 NCBI chr17:33,865,207...33,904,432
Ensembl chr17:33,865,207...33,905,834 		JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
increases expression		 ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]
pterostilbene results in increased expression of HSPA5 mRNA; pterostilbene results in increased expression of HSPA5 protein		 CTD PMID:25341683 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559 		JBrowse link
G Hspa9 heat shock protein 9 increases expression ISO pterostilbene results in increased expression of HSPA9 mRNA CTD PMID:22450950 NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410 		JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) decreases expression ISO pterostilbene results in decreased expression of HSPE1 protein CTD PMID:24936659 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466 		JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IFNG protein]
pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]		 CTD PMID:19549798 PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]] CTD PMID:34474091 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO
EXP		 NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1A protein]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]		 CTD PMID:34405320 PMID:34474091 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:19549798 PMID:22698256 PMID:34474091 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL6 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]		 CTD PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Ins1 insulin I multiple interactions EXP pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:26700463 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Itgb8 integrin beta 8 decreases expression
increases expression		 ISO pterostilbene results in decreased expression of ITGB8 mRNA
pterostilbene results in increased expression of ITGB8 mRNA		 CTD PMID:22450950 NCBI chr12:119,121,757...119,202,891
Ensembl chr12:119,121,757...119,202,537 		JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO pterostilbene results in decreased phosphorylation of JAK2 protein CTD PMID:23313376 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Jun jun proto-oncogene multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein] CTD PMID:18551458 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions EXP pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:26700463 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) multiple interactions
increases expression		 ISO MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]
pterostilbene results in increased expression of KLF2 mRNA; pterostilbene results in increased expression of KLF2 protein		 CTD PMID:26443543 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of LAMP1 protein] CTD PMID:34405320 NCBI chr 8:13,209,161...13,225,338
Ensembl chr 8:13,209,161...13,225,338 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO pterostilbene results in decreased expression of LDLR mRNA CTD PMID:22153697 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]] CTD PMID:34405320 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK1 protein
pterostilbene results in decreased phosphorylation of MAPK1 protein		 CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]] CTD PMID:19549798 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK3 protein
pterostilbene results in decreased phosphorylation of MAPK3 protein		 CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions
increases phosphorylation		 ISO MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein] CTD PMID:26443543 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 PMID:24154491 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK9 protein CTD PMID:19447859 PMID:24154491 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 decreases expression ISO pterostilbene results in decreased expression of MCL1 protein CTD PMID:23313376 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mlkl mixed lineage kinase domain-like multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased phosphorylation of MLKL protein] CTD PMID:34474091 NCBI chr 8:112,037,879...112,065,081
Ensembl chr 8:112,038,429...112,064,809 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein] CTD PMID:20681671 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp28 matrix metallopeptidase 28 (epilysin) multiple interactions EXP pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP26 protein] CTD PMID:20681671 NCBI chr11:83,331,594...83,353,890
Ensembl chr11:83,331,594...83,353,897 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions EXP pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP7 protein]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of MMP7 mRNA]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein] CTD PMID:20681671 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity
multiple interactions		 ISO
EXP		 pterostilbene results in decreased expression of MMP9 mRNA
pterostilbene results in decreased activity of MMP9 protein
pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein]
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]		 CTD PMID:19447859 PMID:19617202 PMID:20152895 PMID:20681671 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO pterostilbene results in decreased expression of MYC protein CTD PMID:19549798 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr14:56,062,252...56,071,400
Ensembl chr14:56,060,601...56,071,400 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
affects localization
increases expression
increases phosphorylation		 EXP
ISO		 NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; pterostilbene results in increased expression of and results in increased localization of NFE2L2 protein; pterostilbene results in increased phosphorylation of and affects the localization of NFE2L2 protein
pterostilbene affects the localization of NFE2L2 protein
pterostilbene results in increased expression of NFE2L2 protein
pterostilbene results in increased phosphorylation of NFE2L2 protein
2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde affects the localization of NFE2L2 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]		 CTD PMID:21355597 PMID:25341683 PMID:26700463 PMID:31139082 PMID:33930484 More... NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:18852136 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO
EXP		 [pterostilbene co-treated with Quercetin] results in decreased degradation of NFKBIA protein; [pterostilbene co-treated with Quercetin] results in decreased phosphorylation of NFKBIA protein
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]		 CTD PMID:18551458 PMID:18852136 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]] CTD PMID:34474091 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO
EXP		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]		 CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22698256 More... NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression
multiple interactions		 ISO pterostilbene results in increased expression of NQO1 mRNA; pterostilbene results in increased expression of NQO1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of NQO1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]		 CTD PMID:25111660 PMID:25341683 PMID:31139082 PMID:34474091 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 increases expression ISO pterostilbene results in increased expression of NQO2 mRNA; pterostilbene results in increased expression of NQO2 protein CTD PMID:24936659 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
affects binding		 ISO pterostilbene binds to and results in increased activity of NR1I2 protein
pterostilbene binds to NR1I2 protein		 CTD PMID:20869355 PMID:30394306 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO pterostilbene binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases expression
multiple interactions		 ISO pterostilbene results in increased expression of PARP1 protein modified form
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein]		 CTD PMID:19549798 PMID:33930484 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO pterostilbene results in decreased expression of PCNA protein CTD PMID:20398797 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression ISO pterostilbene results in increased expression of PDK4 mRNA CTD PMID:26443543 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression ISO pterostilbene results in decreased expression of PGAM1 protein CTD PMID:24936659 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO [resveratrol co-treated with pterostilbene] promotes the reaction [afimoxifene results in decreased expression of PGR mRNA]; [resveratrol co-treated with pterostilbene] promotes the reaction [Estradiol results in increased expression of PGR mRNA] CTD PMID:27159275 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO pterostilbene binds to and results in increased activity of PPARA protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]		 CTD PMID:15853379 PMID:34474091 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO pterostilbene results in increased expression of PPARGC1A mRNA CTD PMID:26443543 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions
increases phosphorylation		 ISO PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein]
pterostilbene results in increased phosphorylation of PRKAA1 protein		 CTD PMID:26443543 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions EXP pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:21355597 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) decreases expression ISO pterostilbene results in decreased expression of PSME3 protein CTD PMID:24936659 NCBI chr11:101,206,090...101,214,363
Ensembl chr11:101,207,039...101,214,363 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]		 CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22842666 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]] CTD PMID:34474091 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO pterostilbene results in decreased expression of RB1 protein CTD PMID:20398797 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO
EXP		 [pterostilbene co-treated with Quercetin] affects the localization of RELA protein; [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]		 CTD PMID:18551458 PMID:18852136 PMID:21355597 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein] CTD PMID:34474091 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]] CTD PMID:34474091 NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322 		JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO pterostilbene results in decreased expression of RPS12 protein CTD PMID:24936659 NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO pterostilbene results in increased expression of SARS1 mRNA CTD PMID:22450950 NCBI chr 3:108,332,180...108,352,575
Ensembl chr 3:108,332,181...108,352,525 		JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]] CTD PMID:34405320 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 mRNA; [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 protein CTD PMID:26459286 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Sirt2 sirtuin 2 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of SIRT2 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr 7:28,466,192...28,488,086
Ensembl chr 7:28,466,160...28,488,086 		JBrowse link
G Slc22a12 solute carrier family 22 (organic anion/cation transporter), member 12 multiple interactions EXP pterostilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062 		JBrowse link
G Snai1 snail family zinc finger 1 decreases expression ISO pterostilbene results in decreased expression of SNAI1 protein CTD PMID:23921149 NCBI chr 2:167,380,115...167,384,734
Ensembl chr 2:167,380,115...167,384,734 		JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
increases expression		 ISO [pterostilbene co-treated with kaempferol] results in increased expression of SOD1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of SOD1 protein; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of SOD1 mRNA]
pterostilbene results in increased expression of SOD1 protein		 CTD PMID:25111660 PMID:33930484 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
increases expression
increases activity		 ISO
EXP		 [pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein; HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]; pterostilbene results in increased expression of and results in increased activity of SOD2 protein; SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein]
pterostilbene results in increased expression of SOD2 protein
ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]
pterostilbene results in increased activity of SOD2 protein		 CTD PMID:18852136 PMID:22450950 PMID:22572619 PMID:24361291 PMID:26443543 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sp1 trans-acting transcription factor 1 multiple interactions ISO SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein] CTD PMID:18852136 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO
EXP		 bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; Cycloheximide promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] CTD PMID:34405320 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
decreases phosphorylation
decreases activity		 ISO
EXP		 pterostilbene results in decreased expression of STAT3 protein modified form
pterostilbene results in decreased phosphorylation of STAT3 protein
pterostilbene results in decreased activity of STAT3 protein		 CTD PMID:22450950 PMID:23313376 PMID:26138072 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO pterostilbene results in increased phosphorylation of STK11 protein CTD PMID:26443543 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516 		JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of TERF1 protein] CTD PMID:34405320 NCBI chr 1:15,875,634...15,914,283
Ensembl chr 1:15,875,870...15,914,276 		JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions		 ISO pterostilbene results in decreased expression of TERT mRNA; pterostilbene results in decreased expression of TERT protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT protein]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT mRNA]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT protein]		 CTD PMID:26459286 PMID:34405320 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]]		 CTD PMID:19549798 PMID:22698256 PMID:23731018 PMID:34405320 PMID:34474091 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO pterostilbene results in decreased expression of TPT1 protein CTD PMID:24936659 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965 		JBrowse link
G Trp53 transformation related protein 53 increases expression ISO pterostilbene results in increased expression of TP53 mRNA CTD PMID:20152895 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation
decreases activity
multiple interactions		 ISO UGT1A1 protein results in increased glucuronidation of pterostilbene
pterostilbene results in decreased activity of UGT1A1 protein
pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:23965644 PMID:31812603 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 affects glucuronidation ISO UGT1A10 protein affects the glucuronidation of pterostilbene CTD PMID:23965644 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions
decreases activity
increases glucuronidation		 ISO pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A3 protein
UGT1A3 protein results in increased glucuronidation of pterostilbene		 CTD PMID:23965644 PMID:31812603 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B decreases activity
multiple interactions		 ISO pterostilbene results in decreased activity of UGT1A6 protein
pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:31812603 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 affects glucuronidation
decreases activity
multiple interactions		 ISO UGT1A9 protein affects the glucuronidation of pterostilbene
pterostilbene results in decreased activity of UGT1A9 protein
pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:23965644 PMID:31812603 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 decreases activity
multiple interactions		 ISO pterostilbene results in decreased activity of UGT2B7 protein
pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:31812603 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796 		JBrowse link
G Umod uromodulin multiple interactions EXP pterostilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein] CTD PMID:22865646 NCBI chr 7:119,061,931...119,078,485
Ensembl chr 7:119,061,934...119,078,505 		JBrowse link
G Zfp488 zinc finger protein 488 decreases expression ISO pterostilbene results in decreased expression of ZNF488 mRNA CTD PMID:22450950 NCBI chr14:33,689,023...33,700,986
Ensembl chr14:33,689,027...33,700,721 		JBrowse link
rhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 (alpha) increases activity ISO rhapontigenin analog results in increased activity of ESR1 protein CTD PMID:17935960 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions
increases activity		 ISO Fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein] CTD PMID:17692514 PMID:17935960 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033 		JBrowse link
G Trf transferrin multiple interactions ISO rhapontigenin analog inhibits the reaction [Lipopolysaccharides results in increased activity of TF protein] CTD PMID:16507316 NCBI chr 9:103,086,075...103,107,485
Ensembl chr 9:103,081,200...103,107,643 		JBrowse link
trans-pinosylvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP-binding cassette, sub-family B member 10 decreases expression ISO pinosylvin results in decreased expression of ABCB10 mRNA CTD PMID:23333577 NCBI chr 8:124,679,198...124,709,877
Ensembl chr 8:124,679,198...124,709,861 		JBrowse link
G Abce1 ATP-binding cassette, sub-family E member 1 decreases expression ISO pinosylvin results in decreased expression of ABCE1 mRNA CTD PMID:23333577 NCBI chr 8:80,410,071...80,438,369
Ensembl chr 8:80,410,091...80,438,369 		JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO pinosylvin results in decreased expression of ARHGAP29 mRNA CTD PMID:23333577 NCBI chr 3:121,746,752...121,810,326
Ensembl chr 3:121,746,190...121,810,402 		JBrowse link
G Art1 ADP-ribosyltransferase 1 increases expression ISO pinosylvin results in increased expression of ART1 mRNA CTD PMID:23333577 NCBI chr 7:101,750,913...101,771,410
Ensembl chr 7:101,750,950...101,763,140 		JBrowse link
G Bag2 BCL2-associated athanogene 2 decreases expression ISO pinosylvin results in decreased expression of BAG2 mRNA CTD PMID:23333577 NCBI chr 1:33,784,565...33,796,831
Ensembl chr 1:33,784,565...33,796,876 		JBrowse link
G Bcap29 B cell receptor associated protein 29 decreases expression ISO pinosylvin results in decreased expression of BCAP29 mRNA CTD PMID:23333577 NCBI chr12:31,645,353...31,684,657
Ensembl chr12:31,640,966...31,684,657 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA CTD PMID:23333577 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA CTD PMID:23333577 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Cbx3 chromobox 3 decreases expression ISO pinosylvin results in decreased expression of CBX3 mRNA CTD PMID:23333577 NCBI chr 6:51,447,596...51,460,684
Ensembl chr 6:51,447,340...51,460,684 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO pinosylvin results in decreased expression of CCNA2 protein CTD PMID:23333577 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression		 ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA
pinosylvin results in decreased expression of CCND1 protein		 CTD PMID:23333577 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO pinosylvin results in decreased expression of CCNE1 protein CTD PMID:23333577 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959 		JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO pinosylvin results in decreased expression of CDCA2 mRNA CTD PMID:23333577 NCBI chr14:67,910,629...67,953,290
Ensembl chr14:67,913,780...67,953,290 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO pinosylvin results in decreased expression of CDK2 protein CTD PMID:23333577 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdk2ap1 cyclin dependent kinase 2 associated protein 1 decreases expression ISO pinosylvin results in decreased expression of CDK2AP1 mRNA CTD PMID:23333577 NCBI chr 5:124,483,502...124,492,691
Ensembl chr 5:124,483,480...124,501,145 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO pinosylvin results in decreased expression of CDK4 protein CTD PMID:23333577 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdk8 cyclin dependent kinase 8 decreases expression ISO pinosylvin results in decreased expression of CDK8 mRNA CTD PMID:23333577 NCBI chr 5:146,167,432...146,239,684
Ensembl chr 5:146,168,040...146,239,684 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO pinosylvin results in increased expression of CDKN1A mRNA CTD PMID:23333577 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cenpf centromere protein F decreases expression ISO pinosylvin results in decreased expression of CENPF mRNA CTD PMID:23333577 NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283 		JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO pinosylvin results in increased expression of CEP290 mRNA CTD PMID:23333577 NCBI chr10:100,323,410...100,409,527
Ensembl chr10:100,323,420...100,410,702 		JBrowse link
G Chaf1b chromatin assembly factor 1, subunit B decreases expression ISO pinosylvin results in decreased expression of CHAF1B mRNA CTD PMID:23333577 NCBI chr16:93,680,801...93,703,003
Ensembl chr16:93,680,789...93,703,003 		JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 increases expression ISO pinosylvin results in increased expression of CHD1 mRNA CTD PMID:23333577 NCBI chr17:15,925,229...15,992,874
Ensembl chr17:15,925,229...15,992,872 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO pinosylvin results in decreased expression of CKS2 mRNA CTD PMID:23333577 NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO pinosylvin results in decreased expression of COX5A mRNA CTD PMID:23333577 NCBI chr 9:57,423,012...57,439,710
Ensembl chr 9:57,428,557...57,439,709 		JBrowse link
G Cox7c cytochrome c oxidase subunit 7C decreases expression ISO pinosylvin results in decreased expression of COX7C mRNA CTD PMID:23333577 NCBI chr13:86,192,917...86,194,914
Ensembl chr13:86,192,935...86,195,023 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA; pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein CTD PMID:23333577 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Dchs2 dachsous cadherin related 2 increases expression ISO pinosylvin results in increased expression of DCHS2 mRNA CTD PMID:23333577 NCBI chr 3:83,032,589...83,270,336
Ensembl chr 3:83,035,255...83,264,516 		JBrowse link
G Dhx15 DEAH-box helicase 15 decreases expression ISO pinosylvin results in decreased expression of DHX15 mRNA CTD PMID:23333577 NCBI chr 5:52,307,545...52,347,888
Ensembl chr 5:52,307,545...52,347,856 		JBrowse link
G Dsg1a desmoglein 1 alpha decreases expression ISO pinosylvin results in decreased expression of DSG1 mRNA CTD PMID:23333577 NCBI chr18:20,443,982...20,476,407
Ensembl chr18:20,443,868...20,476,407 		JBrowse link
G Eno1 enolase 1, alpha non-neuron decreases expression ISO pinosylvin results in decreased expression of ENO1 mRNA CTD PMID:23333577 NCBI chr 4:150,321,165...150,333,336
Ensembl chr 4:150,321,178...150,333,336
Ensembl chr18:150,321,178...150,333,336 		JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 increases expression ISO pinosylvin results in increased expression of ERCC1 mRNA CTD PMID:23333577 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449 		JBrowse link
G Etfb electron transferring flavoprotein, beta polypeptide increases expression ISO pinosylvin results in increased expression of ETFB mRNA CTD PMID:23333577 NCBI chr 7:43,093,496...43,107,224
Ensembl chr 7:43,093,507...43,107,224 		JBrowse link
G Fbxo8 F-box protein 8 increases expression ISO pinosylvin results in increased expression of FBXO8 mRNA CTD PMID:23333577 NCBI chr 8:57,004,189...57,046,974
Ensembl chr 8:57,004,125...57,046,974 		JBrowse link
G Fdps farnesyl diphosphate synthetase decreases expression ISO pinosylvin results in decreased expression of FDPS mRNA CTD PMID:23333577 NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266 		JBrowse link
G Fh1 fumarate hydratase 1 decreases expression ISO pinosylvin results in decreased expression of FH mRNA CTD PMID:23333577 NCBI chr 1:175,428,944...175,453,201
Ensembl chr 1:175,427,940...175,453,201 		JBrowse link
G Fth1 ferritin heavy polypeptide 1 increases expression ISO pinosylvin results in increased expression of FTH1 mRNA CTD PMID:23333577 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression ISO pinosylvin results in increased expression of GADD45A mRNA CTD PMID:23333577 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO pinosylvin results in increased expression of GDF15 mRNA; pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression ISO pinosylvin results in decreased expression of GNAI1 mRNA CTD PMID:23333577 NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353 		JBrowse link
G Gtf2h5 general transcription factor IIH, polypeptide 5 decreases expression ISO pinosylvin results in decreased expression of GTF2H5 mRNA CTD PMID:23333577 NCBI chr17:6,130,103...6,135,763
Ensembl chr17:6,130,061...6,136,792 		JBrowse link
G H3f3b H3.3 histone B decreases expression ISO pinosylvin results in decreased expression of H3-3B mRNA CTD PMID:23333577 NCBI chr11:115,912,787...115,921,313
Ensembl chr11:115,912,738...115,918,788 		JBrowse link
G Hal histidine ammonia lyase increases expression ISO pinosylvin results in increased expression of HAL mRNA CTD PMID:23333577 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166 		JBrowse link
G Hmox2 heme oxygenase 2 increases expression ISO pinosylvin results in increased expression of HMOX2 mRNA CTD PMID:23333577 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 decreases expression ISO pinosylvin results in decreased expression of HSP90AB1 mRNA CTD PMID:23333577 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions
decreases expression		 ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA
pinosylvin results in decreased expression of ID2 mRNA		 CTD PMID:23333577 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO pinosylvin results in decreased expression of IDI1 mRNA CTD PMID:23333577 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein decreases expression ISO pinosylvin results in decreased expression of IL1RAP mRNA CTD PMID:23333577 NCBI chr16:26,400,259...26,548,878
Ensembl chr16:26,400,454...26,548,867 		JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 increases expression ISO pinosylvin results in increased expression of IRF2BP1 mRNA CTD PMID:23333577 NCBI chr 7:18,737,983...18,740,688
Ensembl chr 7:18,737,969...18,740,702 		JBrowse link
G Jag1 jagged 1 increases expression ISO pinosylvin results in increased expression of JAG1 mRNA CTD PMID:23333577 NCBI chr 2:136,923,371...136,958,440
Ensembl chr 2:136,923,376...136,958,564 		JBrowse link
G Kbtbd6 kelch repeat and BTB (POZ) domain containing 6 decreases expression ISO pinosylvin results in decreased expression of KBTBD6 mRNA CTD PMID:23333577 NCBI chr14:79,689,275...79,692,256
Ensembl chr14:79,689,275...79,692,258 		JBrowse link
G Lrrc25 leucine rich repeat containing 25 increases expression ISO pinosylvin results in increased expression of LRRC25 mRNA CTD PMID:23333577 NCBI chr 8:71,068,810...71,073,501
Ensembl chr 8:71,068,805...71,074,133 		JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO pinosylvin results in decreased expression of LSM6 mRNA CTD PMID:23333577 NCBI chr 8:79,531,497...79,547,781
Ensembl chr 8:79,531,494...79,547,769 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO pinosylvin results in decreased expression of MCM5 mRNA CTD PMID:23333577 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067 		JBrowse link
G Metap2 methionine aminopeptidase 2 decreases expression ISO pinosylvin results in decreased expression of METAP2 mRNA CTD PMID:23333577 NCBI chr10:93,694,351...93,732,952
Ensembl chr10:93,694,351...93,732,955 		JBrowse link
G Mex3d mex3 RNA binding family member D decreases expression ISO pinosylvin results in decreased expression of MEX3D mRNA CTD PMID:23333577 NCBI chr10:80,216,189...80,223,485
Ensembl chr10:80,216,189...80,223,493 		JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA CTD PMID:23333577 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,587 		JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 decreases expression ISO pinosylvin results in decreased expression of MRPL14 mRNA CTD PMID:23333577 NCBI chr17:45,991,689...46,009,421
Ensembl chr17:45,997,248...46,009,421 		JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 decreases expression ISO pinosylvin results in decreased expression of MRPL41 mRNA CTD PMID:23333577 NCBI chr 2:24,862,482...24,865,110
Ensembl chr 2:24,864,129...24,865,110 		JBrowse link
G Mt4 metallothionein 4 increases expression ISO pinosylvin results in increased expression of MT4 mRNA CTD PMID:23333577 NCBI chr 8:94,863,832...94,865,659
Ensembl chr 8:94,863,825...94,865,659 		JBrowse link
G Myc myelocytomatosis oncogene multiple interactions
decreases expression		 ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA
pinosylvin results in decreased expression of MYC protein		 CTD PMID:23333577 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Nup35 nucleoporin 35 decreases expression ISO pinosylvin results in decreased expression of NUP35 mRNA CTD PMID:23333577 NCBI chr 2:80,469,156...80,490,415
Ensembl chr 2:80,447,580...80,489,250 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 decreases expression ISO pinosylvin results in decreased expression of OAZ1 mRNA CTD PMID:23333577 NCBI chr10:80,662,490...80,665,124
Ensembl chr10:80,662,516...80,665,124 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO pinosylvin results in decreased expression of PCNA mRNA CTD PMID:23333577 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Polr2j polymerase (RNA) II (DNA directed) polypeptide J increases expression ISO pinosylvin results in increased expression of POLR2J mRNA CTD PMID:23333577 NCBI chr 5:136,145,545...136,151,801
Ensembl chr 5:136,145,485...136,151,801 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase decreases expression ISO pinosylvin results in decreased expression of PPAT mRNA CTD PMID:23333577 NCBI chr 5:77,061,096...77,099,425
Ensembl chr 5:77,061,096...77,099,425 		JBrowse link
G Ptges2 prostaglandin E synthase 2 decreases expression ISO pinosylvin results in decreased expression of PTGES2 mRNA CTD PMID:23333577 NCBI chr 2:32,285,902...32,292,752
Ensembl chr 2:32,285,908...32,295,784 		JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 decreases expression ISO pinosylvin results in decreased expression of PTK2 protein modified form CTD PMID:23333577 NCBI chr15:73,076,951...73,297,192
Ensembl chr15:73,076,951...73,295,129 		JBrowse link
G Pxmp4 peroxisomal membrane protein 4 increases expression ISO pinosylvin results in increased expression of PXMP4 mRNA CTD PMID:23333577 NCBI chr 2:154,427,678...154,445,592
Ensembl chr 2:154,427,678...154,445,628 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO pinosylvin results in decreased expression of RAD23B mRNA CTD PMID:23333577 NCBI chr 4:55,350,042...55,392,237
Ensembl chr 4:55,350,043...55,392,237 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO pinosylvin results in decreased expression of RB1 protein CTD PMID:23333577 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Rbbp8 retinoblastoma binding protein 8, endonuclease decreases expression ISO pinosylvin results in decreased expression of RBBP8 mRNA CTD PMID:23333577 NCBI chr18:11,766,333...11,876,264
Ensembl chr18:11,766,333...11,878,278 		JBrowse link
G Rbx1 ring-box 1 decreases expression ISO pinosylvin results in decreased expression of RBX1 mRNA CTD PMID:23333577 NCBI chr15:81,350,517...81,360,570
Ensembl chr15:81,350,497...81,360,570 		JBrowse link
G Rrm2 ribonucleotide reductase M2 decreases expression ISO pinosylvin results in decreased expression of RRM2 mRNA CTD PMID:23333577 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145 		JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein increases expression ISO pinosylvin results in increased expression of SEC22B mRNA CTD PMID:23333577 NCBI chr 3:97,808,543...97,829,634
Ensembl chr 3:97,808,506...97,830,592 		JBrowse link
G Serbp1 serpine1 mRNA binding protein 1 decreases expression ISO pinosylvin results in decreased expression of SERBP1 mRNA CTD PMID:23333577 NCBI chr 6:67,243,963...67,266,286
Ensembl chr 6:67,215,160...67,274,720 		JBrowse link
G Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha increases expression ISO pinosylvin results in increased expression of SGTA mRNA CTD PMID:23333577 NCBI chr10:80,879,905...80,896,105
Ensembl chr10:80,879,909...80,896,015 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression ISO pinosylvin results in increased expression of SLC38A2 mRNA CTD PMID:23333577 NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611 		JBrowse link
G Snrpb2 U2 small nuclear ribonucleoprotein B decreases expression ISO pinosylvin results in decreased expression of SNRPB2 mRNA CTD PMID:23333577 NCBI chr 2:142,904,989...142,913,972
Ensembl chr 2:142,904,959...142,914,773 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression ISO pinosylvin results in decreased expression of SNRPG mRNA CTD PMID:23333577 NCBI chr 6:86,348,522...86,355,884
Ensembl chr 6:86,348,286...86,356,310 		JBrowse link
G Src Rous sarcoma oncogene decreases expression ISO pinosylvin results in decreased expression of SRC protein modified form CTD PMID:23333577 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782 		JBrowse link
G Srsf10 serine and arginine-rich splicing factor 10 decreases expression ISO pinosylvin results in decreased expression of SRSF10 mRNA CTD PMID:23333577 NCBI chr 4:135,582,454...135,597,219
Ensembl chr 4:135,583,058...135,597,219 		JBrowse link
G Srsf11 serine and arginine-rich splicing factor 11 decreases expression ISO pinosylvin results in decreased expression of SRSF11 mRNA CTD PMID:23333577 NCBI chr 3:157,716,552...157,742,304
Ensembl chr 3:157,716,110...157,742,276 		JBrowse link
G Srsf3 serine and arginine-rich splicing factor 3 decreases expression ISO pinosylvin results in decreased expression of SFRS3 mRNA CTD PMID:23333577 NCBI chr17:29,251,634...29,262,346
Ensembl chr17:29,251,602...29,262,347 		JBrowse link
G Ssbp1 single-stranded DNA binding protein 1 decreases expression ISO pinosylvin results in decreased expression of SSBP1 mRNA CTD PMID:23333577 NCBI chr 6:40,448,302...40,458,757
Ensembl chr 6:40,448,286...40,461,634 		JBrowse link
G Stx6 syntaxin 6 increases expression ISO pinosylvin results in increased expression of STX6 mRNA CTD PMID:23333577 NCBI chr 1:155,034,374...155,083,405
Ensembl chr 1:155,034,461...155,084,002 		JBrowse link
G Tbc1d25 TBC1 domain family, member 25 increases expression ISO pinosylvin results in increased expression of TBC1D25 mRNA CTD PMID:23333577 NCBI chr  X:8,020,709...8,042,420
Ensembl chr  X:8,020,711...8,042,420 		JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 decreases expression ISO pinosylvin results in decreased expression of TIMM13 mRNA CTD PMID:23333577 NCBI chr10:80,735,284...80,736,803
Ensembl chr10:80,735,284...80,736,803 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression ISO pinosylvin results in increased expression of TMED2 mRNA CTD PMID:23333577 NCBI chr 5:124,678,835...124,688,566
Ensembl chr 5:124,678,758...124,688,569 		JBrowse link
G Tmprss3 transmembrane protease, serine 3 decreases expression ISO pinosylvin results in decreased expression of TMPRSS3 mRNA CTD PMID:23333577 NCBI chr17:31,398,237...31,419,478
Ensembl chr17:31,398,239...31,417,951 		JBrowse link
G Tnrc6c trinucleotide repeat containing 6C decreases expression ISO pinosylvin results in decreased expression of TNRC6C mRNA CTD PMID:23333577 NCBI chr11:117,544,529...117,654,265
Ensembl chr11:117,545,115...117,654,265 		JBrowse link
G Trp53 transformation related protein 53 increases expression ISO pinosylvin results in increased expression of TP53 protein CTD PMID:23333577 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO pinosylvin results in increased expression of TSC22D1 mRNA CTD PMID:23333577 NCBI chr14:76,652,401...76,745,205
Ensembl chr14:76,652,401...76,745,205 		JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression ISO pinosylvin results in decreased expression of TUBA1B mRNA CTD PMID:23333577 NCBI chr15:98,829,310...98,832,271
Ensembl chr15:98,829,306...98,832,446 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO pinosylvin results in decreased expression of TUBB mRNA CTD PMID:23333577 NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198 		JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 decreases expression ISO pinosylvin results in decreased expression of UBE2D1 mRNA CTD PMID:23333577 NCBI chr10:71,090,810...71,121,048
Ensembl chr10:71,090,810...71,121,092 		JBrowse link
G Ubxn2a UBX domain protein 2A decreases expression ISO pinosylvin results in decreased expression of UBXN2A mRNA CTD PMID:23333577 NCBI chr12:4,926,814...4,957,749
Ensembl chr12:4,929,032...4,957,705 		JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 increases expression ISO pinosylvin results in increased expression of UCHL1 mRNA CTD PMID:23333577 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577 		JBrowse link
G Usp22 ubiquitin specific peptidase 22 decreases expression ISO pinosylvin results in decreased expression of USP22 mRNA CTD PMID:23333577 NCBI chr11:61,042,607...61,065,885
Ensembl chr11:61,042,611...61,065,881 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression ISO pinosylvin results in increased expression of USP7 mRNA CTD PMID:23333577 NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172 		JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 decreases expression ISO pinosylvin results in decreased expression of ZBTB44 mRNA CTD PMID:23333577 NCBI chr 9:30,941,016...30,987,181
Ensembl chr 9:30,941,940...30,987,181 		JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO pinosylvin results in decreased expression of ZNF207 mRNA CTD PMID:23333577 NCBI chr11:80,274,105...80,299,387
Ensembl chr11:80,274,105...80,296,559 		JBrowse link
G Zfp330 zinc finger protein 330 decreases expression ISO pinosylvin results in decreased expression of ZNF330 mRNA CTD PMID:23333577 NCBI chr 8:83,490,247...83,500,774
Ensembl chr 8:83,490,236...83,500,789 		JBrowse link
trans-rhaponticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32662907 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] CTD PMID:32662907 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] CTD PMID:32662907 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Ins1 insulin I multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32662907 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] CTD PMID:32662907 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] CTD PMID:32662907 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] CTD PMID:32662907 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] CTD PMID:32662907 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:32662907 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
trans-stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding ISO 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression		 ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA		 CTD PMID:21554123 NCBI chr 4:137,589,548...137,692,540
Ensembl chr 4:137,589,548...137,692,540 		JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression		 ISO 4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein
4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA		 CTD PMID:21554123 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr11:69,501,108...69,508,852
Ensembl chr11:69,505,630...69,508,731 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22307
    chemical entity 22306
      atom 22302
        nonmetal atom 22132
          carbon atom 21924
            organic molecular entity 21924
              olefinic compound 17111
                stilbene 3488
                  trans-stilbene 259
                    N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                    piceatannol + 32
                    pterostilbene 153
                    trans-pinosylvin 102
                    trans-stilben-4-ol 0
                    trans-stilbene-4,4'-diol + 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 22307
    subatomic particle 22302
      composite particle 22302
        hadron 22302
          baryon 22302
            nucleon 22302
              atomic nucleus 22302
                atom 22302
                  main group element atom 22182
                    p-block element atom 22182
                      carbon group element atom 21984
                        carbon atom 21924
                          organic molecular entity 21924
                            organic molecule 21750
                              organic cyclic compound 21366
                                carbocyclic compound 19796
                                  benzenoid aromatic compound 18974
                                    benzenes 18790
                                      stilbene 3488
                                        trans-stilbene 259
                                          N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                                          piceatannol + 32
                                          pterostilbene 153
                                          trans-pinosylvin 102
                                          trans-stilben-4-ol 0
                                          trans-stilbene-4,4'-diol + 10
paths to the root