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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trans-stilbene
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Accession:CHEBI:36007 term browser browse the term
Definition:The trans-isomer of stilbene.
Synonyms:exact_synonym: 1,1'-[(1E)-ethene-1,2-diyl]dibenzene
 related_synonym: (E)-1,2-diphenylethylene;   (E)-stilbene;   1,1'-(E)-ethene-1,2-diyldibenzene;   Formula=C14H12;   InChI=1S/C14H12/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-12H/b12-11+;   InChIKey=PJANXHGTPQOBST-VAWYXSNFSA-N;   SMILES=c1ccc(cc1)\\C=C\\c1ccccc1;   [(E)-2-phenylethenyl]benzene;   trans-1,2-diphenylethylene;   trans-alpha,beta-diphenylethylene
 xref: Beilstein:1616740;   CAS:103-30-0;   Gmelin:4381;   KNApSAcK:C00037932;   PMID:32201774;   PMID:32662469;   PMID:33564098;   Wikipedia:(E)-Stilbene


show annotations for term's descendants           Sort by:
isorhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Hydrogen Peroxide]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G CCND1 cyclin D1 decreases expression EXP isorhapontigenin results in decreased expression of CCND1 protein CTD PMID:37619952 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CDH1 cadherin 1 multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in increased expression of CDH1 protein CTD PMID:37619952 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased localization of CTNNB1 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased phosphorylation of CTNNB1 protein CTD PMID:37619952 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3A protein CTD PMID:37619952 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3B protein CTD PMID:37619952 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO isorhapontigenin affects the expression of FOS protein CTD PMID:15607907 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta affects activity ISO isorhapontigenin affects the activity of IKBKB protein CTD PMID:15607907 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit affects expression ISO isorhapontigenin affects the expression of JUN protein CTD PMID:15607907 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:15607907 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:15607907 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions ISO isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MEG3 maternally expressed 3 multiple interactions EXP isorhapontigenin inhibits the reaction [sodium bichromate results in decreased expression of MEG3] CTD PMID:37619952 NCBI chr14:100,826,108...100,861,026
Ensembl chr14:100,779,206...100,861,031 		JBrowse link
G MKI67 marker of proliferation Ki-67 decreases expression EXP isorhapontigenin results in decreased expression of MKI67 protein CTD PMID:37619952 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423 		JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of and results in decreased localization of NEDD9 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of NEDD9 mRNA CTD PMID:37619952 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO isorhapontigenin affects the degradation of and affects the phosphorylation of NFKBIA protein CTD PMID:15607907 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of SNAI2 protein CTD PMID:37619952 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
pterostilbene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ACADM acyl-CoA dehydrogenase medium chain increases expression EXP pterostilbene results in increased expression of ACADM mRNA CTD PMID:26443543 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of ACOX1 protein CTD PMID:25083823 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177 		JBrowse link
G AHR aryl hydrocarbon receptor increases activity
multiple interactions		 EXP pterostilbene results in increased activity of AHR protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased activity of AHR protein]; pterostilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]		 CTD PMID:28279696 PMID:31004704 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 protein] CTD PMID:21355597 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases expression
increases phosphorylation
multiple interactions		 EXP pterostilbene results in decreased expression of AKT1 mRNA
pterostilbene results in increased phosphorylation of AKT1 protein
pterostilbene results in decreased phosphorylation of and results in decreased activity of AKT1 protein		 CTD PMID:20152895 PMID:24154491 PMID:31139082 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase decreases expression EXP pterostilbene results in decreased expression of AMACR mRNA CTD PMID:20152895 NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104 		JBrowse link
G ATF2 activating transcription factor 2 multiple interactions EXP pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form] CTD PMID:19549798 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATG5 autophagy related 5 multiple interactions ISO
EXP		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]] CTD PMID:34405320 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791 		JBrowse link
G ATG7 autophagy related 7 multiple interactions EXP ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]] CTD PMID:34405320 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G BAD BCL2 associated agonist of cell death increases expression
multiple interactions		 ISO
EXP		 pterostilbene results in increased expression of BAD protein
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAD protein]		 CTD PMID:20681671 PMID:31139082 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases expression EXP pterostilbene results in increased expression of BAK1 protein CTD PMID:23313376 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator affects response to substance
multiple interactions
increases expression		 EXP
ISO		 BAX protein affects the susceptibility to pterostilbene
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
pterostilbene results in increased expression of BAX mRNA; pterostilbene results in increased expression of BAX protein		 CTD PMID:20152895 PMID:20681671 PMID:22572619 PMID:23313376 PMID:24936659 More... NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
increases expression		 EXP
ISO		 [pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein; pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene results in decreased expression of BCL2 mRNA; pterostilbene results in decreased expression of BCL2 protein
pterostilbene results in increased expression of BCL2 protein		 CTD PMID:18852136 PMID:20152895 PMID:20681671 PMID:24936659 PMID:31139082 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 increases expression
multiple interactions
decreases expression		 ISO
EXP		 pterostilbene results in increased expression of BCL2L1 protein
pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2L1 protein]
pterostilbene results in decreased expression of BCL2L1 protein		 CTD PMID:20681671 PMID:23313376 PMID:31139082 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BECN1 beclin 1 multiple interactions ISO
EXP		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]
BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]		 CTD PMID:34405320 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BID BH3 interacting domain death agonist increases expression ISO pterostilbene results in increased expression of BID protein modified form CTD PMID:20681671 NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770 		JBrowse link
G CAMP cathelicidin antimicrobial peptide multiple interactions
increases expression		 EXP calcipotriene promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP protein]; paricalcitol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP protein]
pterostilbene results in increased expression of CAMP mRNA; pterostilbene results in increased expression of CAMP protein		 CTD PMID:24039193 NCBI chr 3:48,223,495...48,225,485
Ensembl chr 3:48,223,347...48,225,491 		JBrowse link
G CASP1 caspase 1 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]] CTD PMID:34474091 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CASP3 caspase 3 increases cleavage
increases expression
increases activity
multiple interactions		 ISO
EXP		 pterostilbene results in increased cleavage of CASP3 protein
pterostilbene results in increased expression of CASP3 mRNA
pterostilbene results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP3 protein]; pterostilbene inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]		 CTD PMID:20152895 PMID:20681671 PMID:23313376 PMID:24936659 PMID:25341683 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP4 caspase 4 multiple interactions
increases activity		 EXP 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CASP7 caspase 7 multiple interactions EXP pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP7 protein] CTD PMID:33930484 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G CASP8 caspase 8 multiple interactions ISO pterostilbene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:20681671 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 increases expression
multiple interactions
increases activity
increases cleavage		 EXP
ISO		 pterostilbene results in increased expression of CASP9 protein
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein]
pterostilbene results in increased cleavage of CASP9 protein		 CTD PMID:20152895 PMID:20681671 PMID:25341683 PMID:33930484 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions
increases expression		 EXP
ISO		 CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]
pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]
pterostilbene results in increased expression of CAT mRNA		 CTD PMID:25341683 PMID:26700463 PMID:34474091 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CCN1 cellular communication network factor 1 multiple interactions ISO
EXP		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]
3-methyladenine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; Ammonium Chloride inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; Chloroquine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]		 CTD PMID:34405320 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCND1 cyclin D1 decreases expression
multiple interactions		 EXP
ISO		 pterostilbene results in decreased expression of CCND1 protein
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 protein]		 CTD PMID:19549798 PMID:20398797 PMID:20681671 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNE1 cyclin E1 decreases expression ISO pterostilbene results in decreased expression of CCNE1 protein CTD PMID:20398797 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDH1 cadherin 1 multiple interactions
increases expression		 ISO
EXP		 pterostilbene inhibits the reaction [Azoxymethane results in decreased expression of CDH1 protein]
pterostilbene results in increased expression of CDH1 protein		 CTD PMID:20681671 PMID:23921149 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression ISO pterostilbene results in decreased expression of CDK2 protein CTD PMID:20398797 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression ISO pterostilbene results in decreased expression of CDK4 protein CTD PMID:20398797 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 EXP
ISO		 pterostilbene results in increased expression of CDKN1A protein
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]		 CTD PMID:23313376 PMID:34405320 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B increases expression EXP pterostilbene results in increased expression of CDKN1B protein CTD PMID:23313376 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A multiple interactions EXP
ISO		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]] CTD PMID:34405320 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of CPT1A protein CTD PMID:25083823 NCBI chr11:68,754,620...68,844,277
Ensembl chr11:68,754,620...68,844,410 		JBrowse link
G CRP C-reactive protein multiple interactions EXP [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CXCL3 C-X-C motif chemokine ligand 3 increases expression EXP pterostilbene results in increased expression of CXCL3 mRNA CTD PMID:22450950 NCBI chr 4:74,036,589...74,038,689
Ensembl chr 4:74,036,589...74,038,807 		JBrowse link
G CYCS cytochrome c, somatic affects localization
increases expression		 EXP pterostilbene affects the localization of CYCS protein
pterostilbene results in increased expression of CYCS mRNA; pterostilbene results in increased expression of CYCS protein		 CTD PMID:22450950 PMID:22572619 PMID:26443543 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression
multiple interactions
increases expression		 EXP pterostilbene results in decreased expression of CYP1A1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased expression of CYP1A1 protein]		 CTD PMID:22450950 PMID:31004704 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity ISO
EXP		 pterostilbene results in decreased activity of CYP1A2 protein CTD PMID:16684708 PMID:30394306 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 increases expression EXP pterostilbene results in increased expression of CYP2B6 mRNA CTD PMID:30394306 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 decreases activity EXP pterostilbene results in decreased activity of CYP2C19 protein CTD PMID:30394306 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression		 EXP 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]
pterostilbene results in increased expression of DDIT3 mRNA; pterostilbene results in increased expression of DDIT3 protein		 CTD PMID:22450950 PMID:25341683 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DFFA DNA fragmentation factor subunit alpha increases cleavage ISO pterostilbene results in increased cleavage of DFFA protein CTD PMID:20681671 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529 		JBrowse link
G DHRS2 dehydrogenase/reductase 2 increases expression EXP pterostilbene results in increased expression of DHRS2 mRNA; pterostilbene results in increased expression of DHRS2 protein CTD PMID:24936659 NCBI chr14:23,630,115...23,645,639
Ensembl chr14:23,630,115...23,645,639 		JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein increases expression
affects localization		 EXP pterostilbene results in increased expression of DIABLO protein
pterostilbene affects the localization of DIABLO protein		 CTD PMID:22450950 PMID:22572619 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062 		JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT1 mRNA CTD PMID:26459286 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286 		JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT3A mRNA CTD PMID:26459286 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta multiple interactions EXP pterostilbene promotes the reaction [resveratrol results in decreased expression of DNMT3B mRNA] CTD PMID:26459286 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] CTD PMID:19447859 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EGFR epidermal growth factor receptor multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EIF2A eukaryotic translation initiation factor 2A increases phosphorylation EXP pterostilbene results in increased phosphorylation of EIF2A protein CTD PMID:25341683 NCBI chr 3:150,546,787...150,586,016
Ensembl chr 3:150,546,678...150,586,016 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation		 EXP 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions EXP pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form] CTD PMID:19549798 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,520...47,650,604 		JBrowse link
G ESR1 estrogen receptor 1 increases expression
multiple interactions		 EXP pterostilbene results in increased expression of ESR1 protein
[resveratrol co-treated with pterostilbene] results in increased expression of ESR1 mRNA; [resveratrol co-treated with pterostilbene] results in increased expression of ESR1 protein		 CTD PMID:27159275 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 multiple interactions ISO ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein] CTD PMID:24361291 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G FAS Fas cell surface death receptor increases expression ISO pterostilbene results in increased expression of FAS protein CTD PMID:20681671 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand increases expression ISO pterostilbene results in increased expression of FASL protein CTD PMID:20681671 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FASN fatty acid synthase multiple interactions ISO [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein CTD PMID:25083823 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein] CTD PMID:18551458 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FUT1 fucosyltransferase 1 (H blood group) increases expression EXP pterostilbene results in increased expression of FUT1 mRNA CTD PMID:22450950 NCBI chr19:48,748,011...48,755,358
Ensembl chr19:48,748,011...48,755,390 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP pterostilbene results in increased expression of GDF15 mRNA CTD PMID:22450950 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GLO1 glyoxalase I multiple interactions EXP pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein] CTD PMID:33930484 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145 		JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA] CTD PMID:25341683 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein] CTD PMID:20681671 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSR glutathione-disulfide reductase multiple interactions
decreases expression		 ISO
EXP		 NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]
pterostilbene results in decreased expression of GSR mRNA		 CTD PMID:21355597 PMID:25341683 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP
ISO		 [Resveratrol co-treated with pterostilbene] results in decreased expression of H2AX protein modified form; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]] CTD PMID:26459286 PMID:34405320 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HDAC5 histone deacetylase 5 multiple interactions
increases phosphorylation		 EXP HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter] CTD PMID:26443543 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G HMGA1 high mobility group AT-hook 1 multiple interactions EXP
ISO		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of HMGA1 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]		 CTD PMID:34405320 PMID:34474091 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMGB1 high mobility group box 1 multiple interactions EXP NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]] CTD PMID:34474091 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression
multiple interactions		 EXP
ISO		 pterostilbene results in increased expression of HMOX1 mRNA; pterostilbene results in increased expression of HMOX1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of HMOX1 mRNA; pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 mRNA]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]
NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 protein]		 CTD PMID:21355597 PMID:22450950 PMID:25111660 PMID:31139082 PMID:33930484 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNRNPM heterogeneous nuclear ribonucleoprotein M increases expression EXP pterostilbene results in increased expression of HNRNPM mRNA CTD PMID:22450950 NCBI chr19:8,444,975...8,489,114
Ensembl chr19:8,444,767...8,489,114 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression		 EXP 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]
pterostilbene results in increased expression of HSPA5 mRNA; pterostilbene results in increased expression of HSPA5 protein		 CTD PMID:25341683 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 increases expression EXP pterostilbene results in increased expression of HSPA9 mRNA CTD PMID:22450950 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPE1 heat shock protein family E (Hsp10) member 1 decreases expression EXP pterostilbene results in decreased expression of HSPE1 protein CTD PMID:24936659 NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449 		JBrowse link
G IFNG interferon gamma multiple interactions EXP
ISO		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IFNG protein]
pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]		 CTD PMID:19549798 PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IL18 interleukin 18 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]] CTD PMID:34474091 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions EXP
ISO		 NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1A protein]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]		 CTD PMID:34405320 PMID:34474091 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:19549798 PMID:22698256 PMID:34474091 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions ISO
EXP		 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL6 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]		 CTD PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:26700463 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G ITGB8 integrin subunit beta 8 decreases expression
increases expression		 EXP pterostilbene results in decreased expression of ITGB8 mRNA
pterostilbene results in increased expression of ITGB8 mRNA		 CTD PMID:22450950 NCBI chr 7:20,329,766...20,415,754
Ensembl chr 7:20,330,702...20,415,754 		JBrowse link
G JAK2 Janus kinase 2 decreases phosphorylation EXP pterostilbene results in decreased phosphorylation of JAK2 protein CTD PMID:23313376 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein] CTD PMID:18551458 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:26700463 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G KLF2 KLF transcription factor 2 multiple interactions
increases expression		 EXP MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]
pterostilbene results in increased expression of KLF2 mRNA; pterostilbene results in increased expression of KLF2 protein		 CTD PMID:26443543 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685 		JBrowse link
G LAMP1 lysosomal associated membrane protein 1 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in decreased expression of LAMP1 protein] CTD PMID:34405320 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672 		JBrowse link
G LDLR low density lipoprotein receptor decreases expression EXP pterostilbene results in decreased expression of LDLR mRNA CTD PMID:22153697 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]] CTD PMID:34405320 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK1 protein
pterostilbene results in decreased phosphorylation of MAPK1 protein		 CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 multiple interactions EXP MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]] CTD PMID:19549798 NCBI chr 6:36,027,808...36,124,214
Ensembl chr 6:36,027,752...36,122,511 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK3 protein
pterostilbene results in decreased phosphorylation of MAPK3 protein		 CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MAPK7 mitogen-activated protein kinase 7 multiple interactions
increases phosphorylation		 EXP MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein] CTD PMID:26443543 NCBI chr17:19,377,750...19,383,544
Ensembl chr17:19,377,721...19,383,544 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 PMID:24154491 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK9 protein CTD PMID:19447859 PMID:24154491 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression EXP pterostilbene results in decreased expression of MCL1 protein CTD PMID:23313376 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased phosphorylation of MLKL protein] CTD PMID:34474091 NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein] CTD PMID:20681671 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP28 matrix metallopeptidase 28 multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP26 protein] CTD PMID:20681671 NCBI chr17:35,756,249...35,795,641
Ensembl chr17:35,756,249...35,795,707 		JBrowse link
G MMP7 matrix metallopeptidase 7 multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP7 protein]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of MMP7 mRNA]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein] CTD PMID:20681671 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP9 matrix metallopeptidase 9 decreases expression
decreases activity
multiple interactions		 EXP
ISO		 pterostilbene results in decreased expression of MMP9 mRNA
pterostilbene results in decreased activity of MMP9 protein
pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein]
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]		 CTD PMID:19447859 PMID:19617202 PMID:20152895 PMID:20681671 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP pterostilbene results in decreased expression of MYC protein CTD PMID:19549798 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 multiple interactions EXP NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
increases expression
increases phosphorylation		 ISO
EXP		 NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; pterostilbene results in increased expression of and results in increased localization of NFE2L2 protein; pterostilbene results in increased phosphorylation of and affects the localization of NFE2L2 protein
pterostilbene affects the localization of NFE2L2 protein
pterostilbene results in increased expression of NFE2L2 protein
pterostilbene results in increased phosphorylation of NFE2L2 protein
2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde affects the localization of NFE2L2 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]		 CTD PMID:21355597 PMID:25341683 PMID:26700463 PMID:31139082 PMID:33930484 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:18852136 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions EXP
ISO		 [pterostilbene co-treated with Quercetin] results in decreased degradation of NFKBIA protein; [pterostilbene co-treated with Quercetin] results in decreased phosphorylation of NFKBIA protein
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]		 CTD PMID:18551458 PMID:18852136 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]] CTD PMID:34474091 NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,332,331...247,449,108 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP
ISO		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]		 CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22698256 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 EXP pterostilbene results in increased expression of NQO1 mRNA; pterostilbene results in increased expression of NQO1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of NQO1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]		 CTD PMID:25111660 PMID:25341683 PMID:31139082 PMID:34474091 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 increases expression EXP pterostilbene results in increased expression of NQO2 mRNA; pterostilbene results in increased expression of NQO2 protein CTD PMID:24936659 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755 		JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions
affects binding		 EXP pterostilbene binds to and results in increased activity of NR1I2 protein
pterostilbene binds to NR1I2 protein		 CTD PMID:20869355 PMID:30394306 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487 		JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions EXP pterostilbene binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases expression
multiple interactions		 EXP pterostilbene results in increased expression of PARP1 protein modified form
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein]		 CTD PMID:19549798 PMID:33930484 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression ISO pterostilbene results in decreased expression of PCNA protein CTD PMID:20398797 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 increases expression EXP pterostilbene results in increased expression of PDK4 mRNA CTD PMID:26443543 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 decreases expression EXP pterostilbene results in decreased expression of PGAM1 protein CTD PMID:24936659 NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444 		JBrowse link
G PGR progesterone receptor multiple interactions EXP [resveratrol co-treated with pterostilbene] promotes the reaction [afimoxifene results in decreased expression of PGR mRNA]; [resveratrol co-treated with pterostilbene] promotes the reaction [Estradiol results in increased expression of PGR mRNA] CTD PMID:27159275 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions ISO
EXP		 pterostilbene binds to and results in increased activity of PPARA protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]		 CTD PMID:15853379 PMID:34474091 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha increases expression EXP pterostilbene results in increased expression of PPARGC1A mRNA CTD PMID:26443543 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases phosphorylation		 EXP PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein]
pterostilbene results in increased phosphorylation of PRKAA1 protein		 CTD PMID:26443543 NCBI chr 5:40,759,389...40,798,374
Ensembl chr 5:40,759,389...40,798,374 		JBrowse link
G PRKCB protein kinase C beta multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:21355597 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PSME3 proteasome activator subunit 3 decreases expression EXP pterostilbene results in decreased expression of PSME3 protein CTD PMID:24936659 NCBI chr17:42,833,397...42,843,760
Ensembl chr17:42,824,385...42,843,760 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]		 CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22842666 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]] CTD PMID:34474091 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RB1 RB transcriptional corepressor 1 decreases expression ISO pterostilbene results in decreased expression of RB1 protein CTD PMID:20398797 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO		 [pterostilbene co-treated with Quercetin] affects the localization of RELA protein; [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]		 CTD PMID:18551458 PMID:18852136 PMID:21355597 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 multiple interactions EXP NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein] CTD PMID:34474091 NCBI chr 6:3,063,967...3,115,187
Ensembl chr 6:3,063,824...3,115,187 		JBrowse link
G RIPK3 receptor interacting serine/threonine kinase 3 multiple interactions EXP NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]] CTD PMID:34474091 NCBI chr14:24,336,025...24,339,991
Ensembl chr14:24,336,025...24,340,022 		JBrowse link
G RPS12 ribosomal protein S12 decreases expression EXP pterostilbene results in decreased expression of RPS12 protein CTD PMID:24936659 NCBI chr 6:132,814,569...132,817,564
Ensembl chr 6:132,814,569...132,817,564 		JBrowse link
G SARS1 seryl-tRNA synthetase 1 increases expression EXP pterostilbene results in increased expression of SARS1 mRNA CTD PMID:22450950 NCBI chr 1:109,213,893...109,238,182
Ensembl chr 1:109,213,918...109,238,182 		JBrowse link
G SESN2 sestrin 2 multiple interactions EXP
ISO		 pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]
pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]]		 CTD PMID:34405320 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491 		JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 mRNA; [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 protein CTD PMID:26459286 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390 		JBrowse link
G SIRT2 sirtuin 2 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in decreased expression of SIRT2 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862 		JBrowse link
G SLC22A12 solute carrier family 22 member 12 multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr11:64,591,220...64,602,344
Ensembl chr11:64,590,641...64,602,353 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 decreases expression EXP pterostilbene results in decreased expression of SNAI1 protein CTD PMID:23921149 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases expression		 EXP [pterostilbene co-treated with kaempferol] results in increased expression of SOD1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of SOD1 protein; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of SOD1 mRNA]
pterostilbene results in increased expression of SOD1 protein		 CTD PMID:25111660 PMID:33930484 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression
increases activity		 EXP
ISO		 [pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein; HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]; pterostilbene results in increased expression of and results in increased activity of SOD2 protein; SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein]
pterostilbene results in increased expression of SOD2 protein
ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]
pterostilbene results in increased activity of SOD2 protein		 CTD PMID:18852136 PMID:22450950 PMID:22572619 PMID:24361291 PMID:26443543 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SP1 Sp1 transcription factor multiple interactions EXP SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein] CTD PMID:18852136 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446 		JBrowse link
G SQSTM1 sequestosome 1 multiple interactions ISO
EXP		 pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]
bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; Cycloheximide promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]		 CTD PMID:34405320 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 decreases expression
decreases phosphorylation
decreases activity		 EXP
ISO		 pterostilbene results in decreased expression of STAT3 protein modified form
pterostilbene results in decreased phosphorylation of STAT3 protein
pterostilbene results in decreased activity of STAT3 protein		 CTD PMID:22450950 PMID:23313376 PMID:26138072 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G STK11 serine/threonine kinase 11 increases phosphorylation EXP pterostilbene results in increased phosphorylation of STK11 protein CTD PMID:26443543 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G TERF1 telomeric repeat binding factor 1 multiple interactions EXP pterostilbene inhibits the reaction [Ethanol results in increased expression of TERF1 protein] CTD PMID:34405320 NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123 		JBrowse link
G TERT telomerase reverse transcriptase decreases expression
multiple interactions		 EXP pterostilbene results in decreased expression of TERT mRNA; pterostilbene results in decreased expression of TERT protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT protein]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT mRNA]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT protein]		 CTD PMID:26459286 PMID:34405320 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO		 MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]]		 CTD PMID:19549798 PMID:22698256 PMID:23731018 PMID:34405320 PMID:34474091 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 increases expression EXP pterostilbene results in increased expression of TP53 mRNA CTD PMID:20152895 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TPT1 tumor protein, translationally-controlled 1 decreases expression EXP pterostilbene results in decreased expression of TPT1 protein CTD PMID:24936659 NCBI chr13:45,333,471...45,341,183
Ensembl chr13:45,333,471...45,341,284 		JBrowse link
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
multiple interactions
decreases activity		 EXP UGT1A1 protein results in increased glucuronidation of pterostilbene
pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A1 protein		 CTD PMID:23965644 PMID:31812603 NCBI chr 2:233,760,270...233,773,300
Ensembl chr 2:233,760,270...233,773,300 		JBrowse link
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 affects glucuronidation EXP UGT1A10 protein affects the glucuronidation of pterostilbene CTD PMID:23965644 NCBI chr 2:233,636,448...233,773,300
Ensembl chr 2:233,636,448...233,773,300 		JBrowse link
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 increases glucuronidation
decreases activity
multiple interactions		 EXP UGT1A3 protein results in increased glucuronidation of pterostilbene
pterostilbene results in decreased activity of UGT1A3 protein
pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:23965644 PMID:31812603 NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300 		JBrowse link
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 decreases activity
multiple interactions		 EXP pterostilbene results in decreased activity of UGT1A6 protein
pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]		 CTD PMID:31812603 NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300 		JBrowse link
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 affects glucuronidation
multiple interactions
decreases activity		 EXP UGT1A8 protein affects the glucuronidation of pterostilbene
pterostilbene inhibits the reaction [[UGT1A8 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A8 protein		 CTD PMID:23965644 PMID:31812603 NCBI chr 2:233,617,633...233,773,300
Ensembl chr 2:233,617,633...233,773,300 		JBrowse link
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 affects glucuronidation
multiple interactions
decreases activity		 EXP UGT1A9 protein affects the glucuronidation of pterostilbene
pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A9 protein		 CTD PMID:23965644 PMID:31812603 NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300 		JBrowse link
G UGT2B15 UDP glucuronosyltransferase family 2 member B15 multiple interactions
decreases activity		 EXP pterostilbene inhibits the reaction [[UGT2B15 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT2B15 protein		 CTD PMID:31812603 NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652 		JBrowse link
G UGT2B4 UDP glucuronosyltransferase family 2 member B4 multiple interactions
decreases activity		 EXP pterostilbene inhibits the reaction [[UGT2B4 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT2B4 protein		 CTD PMID:31812603 NCBI chr 4:69,480,165...69,526,014
Ensembl chr 4:69,480,165...69,526,014 		JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 multiple interactions
decreases activity		 EXP pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT2B7 protein		 CTD PMID:31812603 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987 		JBrowse link
G UMOD uromodulin multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein] CTD PMID:22865646 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301 		JBrowse link
G ZBED1 zinc finger BED-type containing 1 decreases expression EXP pterostilbene results in decreased expression of ZBED1 mRNA CTD PMID:22450950 NCBI chr  X:2,486,435...2,500,976
NCBI chr  Y:2,486,435...2,500,976
Ensembl chr  Y:2,486,414...2,500,976
Ensembl chr  X:2,486,414...2,500,976 		JBrowse link
G ZNF488 zinc finger protein 488 decreases expression EXP pterostilbene results in decreased expression of ZNF488 mRNA CTD PMID:22450950 NCBI chr10:47,365,496...47,384,293
Ensembl chr10:47,365,496...47,384,293 		JBrowse link
rhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 increases activity EXP rhapontigenin analog results in increased activity of ESR1 protein CTD PMID:17935960 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 increases activity
multiple interactions		 EXP rhapontigenin analog results in increased activity of ESR2 protein
Fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein]		 CTD PMID:17692514 PMID:17935960 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G TF transferrin multiple interactions EXP rhapontigenin analog inhibits the reaction [Lipopolysaccharides results in increased activity of TF protein] CTD PMID:16507316 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
trans-pinosylvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB10 ATP binding cassette subfamily B member 10 decreases expression EXP pinosylvin results in decreased expression of ABCB10 mRNA CTD PMID:23333577 NCBI chr 1:229,516,582...229,558,707
Ensembl chr 1:229,516,582...229,558,707 		JBrowse link
G ABCE1 ATP binding cassette subfamily E member 1 decreases expression EXP pinosylvin results in decreased expression of ABCE1 mRNA CTD PMID:23333577 NCBI chr 4:145,098,311...145,129,524
Ensembl chr 4:145,098,288...145,129,524 		JBrowse link
G ARHGAP29 Rho GTPase activating protein 29 decreases expression EXP pinosylvin results in decreased expression of ARHGAP29 mRNA CTD PMID:23333577 NCBI chr 1:94,168,905...94,314,592
Ensembl chr 1:94,148,988...94,275,068 		JBrowse link
G ART1 ADP-ribosyltransferase 1 increases expression EXP pinosylvin results in increased expression of ART1 mRNA CTD PMID:23333577 NCBI chr11:3,645,128...3,664,416
Ensembl chr11:3,645,128...3,664,416 		JBrowse link
G BAG2 BAG cochaperone 2 decreases expression EXP pinosylvin results in decreased expression of BAG2 mRNA CTD PMID:23333577 NCBI chr 6:57,172,326...57,189,833
Ensembl chr 6:57,172,326...57,189,833 		JBrowse link
G BCAP29 B cell receptor associated protein 29 decreases expression EXP pinosylvin results in decreased expression of BCAP29 mRNA CTD PMID:23333577 NCBI chr 7:107,580,007...107,623,317
Ensembl chr 7:107,580,246...107,629,170 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA CTD PMID:23333577 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BMP4 bone morphogenetic protein 4 multiple interactions EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA CTD PMID:23333577 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G CBX3 chromobox 3 decreases expression EXP pinosylvin results in decreased expression of CBX3 mRNA CTD PMID:23333577 NCBI chr 7:26,201,443...26,213,607
Ensembl chr 7:26,201,162...26,213,607 		JBrowse link
G CCNA2 cyclin A2 decreases expression EXP pinosylvin results in decreased expression of CCNA2 protein CTD PMID:23333577 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CCND1 cyclin D1 multiple interactions
decreases expression		 EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA
pinosylvin results in decreased expression of CCND1 protein		 CTD PMID:23333577 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CCNE1 cyclin E1 decreases expression EXP pinosylvin results in decreased expression of CCNE1 protein CTD PMID:23333577 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CDCA2 cell division cycle associated 2 decreases expression EXP pinosylvin results in decreased expression of CDCA2 mRNA CTD PMID:23333577 NCBI chr 8:25,458,931...25,507,917
Ensembl chr 8:25,459,199...25,507,911 		JBrowse link
G CDK2 cyclin dependent kinase 2 decreases expression EXP pinosylvin results in decreased expression of CDK2 protein CTD PMID:23333577 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789 		JBrowse link
G CDK2AP1 cyclin dependent kinase 2 associated protein 1 decreases expression EXP pinosylvin results in decreased expression of CDK2AP1 mRNA CTD PMID:23333577 NCBI chr12:123,260,976...123,272,240
Ensembl chr12:123,250,112...123,272,334 		JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression EXP pinosylvin results in decreased expression of CDK4 protein CTD PMID:23333577 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013 		JBrowse link
G CDK8 cyclin dependent kinase 8 decreases expression EXP pinosylvin results in decreased expression of CDK8 mRNA CTD PMID:23333577 NCBI chr13:26,254,129...26,405,238
Ensembl chr13:26,254,104...26,420,982 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP pinosylvin results in increased expression of CDKN1A mRNA CTD PMID:23333577 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CENPF centromere protein F decreases expression EXP pinosylvin results in decreased expression of CENPF mRNA CTD PMID:23333577 NCBI chr 1:214,603,195...214,664,571
Ensembl chr 1:214,603,185...214,664,574 		JBrowse link
G CEP290 centrosomal protein 290 increases expression EXP pinosylvin results in increased expression of CEP290 mRNA CTD PMID:23333577 NCBI chr12:88,049,016...88,142,088
Ensembl chr12:88,049,016...88,142,099 		JBrowse link
G CHAF1B chromatin assembly factor 1 subunit B decreases expression EXP pinosylvin results in decreased expression of CHAF1B mRNA CTD PMID:23333577 NCBI chr21:36,385,392...36,419,015
Ensembl chr21:36,385,392...36,419,015 		JBrowse link
G CHD1 chromodomain helicase DNA binding protein 1 increases expression EXP pinosylvin results in increased expression of CHD1 mRNA CTD PMID:23333577 NCBI chr 5:98,853,985...98,929,007
Ensembl chr 5:98,853,985...98,929,007 		JBrowse link
G CKS2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP pinosylvin results in decreased expression of CKS2 mRNA CTD PMID:23333577 NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703 		JBrowse link
G COX5A cytochrome c oxidase subunit 5A decreases expression EXP pinosylvin results in decreased expression of COX5A mRNA CTD PMID:23333577 NCBI chr15:74,919,791...74,938,073
Ensembl chr15:74,919,791...74,938,083 		JBrowse link
G COX7C cytochrome c oxidase subunit 7C decreases expression EXP pinosylvin results in decreased expression of COX7C mRNA CTD PMID:23333577 NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA; pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein CTD PMID:23333577 NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096 		JBrowse link
G DCHS2 dachsous cadherin-related 2 increases expression EXP pinosylvin results in increased expression of DCHS2 mRNA CTD PMID:23333577 NCBI chr 4:154,231,742...154,491,799
Ensembl chr 4:154,231,742...154,491,799 		JBrowse link
G DHX15 DEAH-box helicase 15 decreases expression EXP pinosylvin results in decreased expression of DHX15 mRNA CTD PMID:23333577 NCBI chr 4:24,527,475...24,584,554
Ensembl chr 4:24,517,441...24,584,554 		JBrowse link
G DLEU2 deleted in lymphocytic leukemia 2 decreases expression EXP pinosylvin results in decreased expression of DLEU2 mRNA CTD PMID:23333577 NCBI chr13:49,982,549...50,125,541
Ensembl chr13:49,956,669...50,126,118 		JBrowse link
G DSG1 desmoglein 1 decreases expression EXP pinosylvin results in decreased expression of DSG1 mRNA CTD PMID:23333577 NCBI chr18:31,318,160...31,359,246
Ensembl chr18:31,318,160...31,359,246 		JBrowse link
G ENO1 enolase 1 decreases expression EXP pinosylvin results in decreased expression of ENO1 mRNA CTD PMID:23333577 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression EXP pinosylvin results in increased expression of ERCC1 mRNA CTD PMID:23333577 NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828 		JBrowse link
G ETFB electron transfer flavoprotein subunit beta increases expression EXP pinosylvin results in increased expression of ETFB mRNA CTD PMID:23333577 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388 		JBrowse link
G FBXO8 F-box protein 8 increases expression EXP pinosylvin results in increased expression of FBXO8 mRNA CTD PMID:23333577 NCBI chr 4:174,236,658...174,283,667
Ensembl chr 4:174,236,658...174,283,667 		JBrowse link
G FDPS farnesyl diphosphate synthase decreases expression EXP pinosylvin results in decreased expression of FDPS mRNA CTD PMID:23333577 NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666 		JBrowse link
G FH fumarate hydratase decreases expression EXP pinosylvin results in decreased expression of FH mRNA CTD PMID:23333577 NCBI chr 1:241,497,603...241,519,755
Ensembl chr 1:241,497,511...241,519,799 		JBrowse link
G FTH1 ferritin heavy chain 1 increases expression EXP pinosylvin results in increased expression of FTH1 mRNA CTD PMID:23333577 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP pinosylvin results in increased expression of GADD45A mRNA CTD PMID:23333577 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP pinosylvin results in increased expression of GDF15 mRNA; pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GNAI1 G protein subunit alpha i1 decreases expression EXP pinosylvin results in decreased expression of GNAI1 mRNA CTD PMID:23333577 NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181 		JBrowse link
G GTF2H5 general transcription factor IIH subunit 5 decreases expression EXP pinosylvin results in decreased expression of GTF2H5 mRNA CTD PMID:23333577 NCBI chr 6:158,168,350...158,199,344
Ensembl chr 6:158,168,350...158,199,344 		JBrowse link
G H3-3B H3.3 histone B decreases expression EXP pinosylvin results in decreased expression of H3-3B mRNA CTD PMID:23333577 NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893 		JBrowse link
G HAL histidine ammonia-lyase increases expression EXP pinosylvin results in increased expression of HAL mRNA CTD PMID:23333577 NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365 		JBrowse link
G HMOX2 heme oxygenase 2 increases expression EXP pinosylvin results in increased expression of HMOX2 mRNA CTD PMID:23333577 NCBI chr16:4,474,736...4,510,347
Ensembl chr16:4,474,690...4,510,347 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 decreases expression EXP pinosylvin results in decreased expression of HSP90AB1 mRNA CTD PMID:23333577 NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888 		JBrowse link
G ID2 inhibitor of DNA binding 2 multiple interactions
decreases expression		 EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA
pinosylvin results in decreased expression of ID2 mRNA		 CTD PMID:23333577 NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461 		JBrowse link
G IDI1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP pinosylvin results in decreased expression of IDI1 mRNA CTD PMID:23333577 NCBI chr10:1,039,152...1,056,704
Ensembl chr10:1,039,152...1,049,119 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein decreases expression EXP pinosylvin results in decreased expression of IL1RAP mRNA CTD PMID:23333577 NCBI chr 3:190,514,085...190,659,750
Ensembl chr 3:190,514,051...190,659,750 		JBrowse link
G IRF2BP1 interferon regulatory factor 2 binding protein 1 increases expression EXP pinosylvin results in increased expression of IRF2BP1 mRNA CTD PMID:23333577 NCBI chr19:45,883,608...45,886,141
Ensembl chr19:45,883,608...45,886,141 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 increases expression EXP pinosylvin results in increased expression of JAG1 mRNA CTD PMID:23333577 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999 		JBrowse link
G KBTBD6 kelch repeat and BTB domain containing 6 decreases expression EXP pinosylvin results in decreased expression of KBTBD6 mRNA CTD PMID:23333577 NCBI chr13:41,127,569...41,132,802
Ensembl chr13:41,127,569...41,132,802 		JBrowse link
G LRRC25 leucine rich repeat containing 25 increases expression EXP pinosylvin results in increased expression of LRRC25 mRNA CTD PMID:23333577 NCBI chr19:18,391,137...18,397,622
Ensembl chr19:18,391,137...18,397,622 		JBrowse link
G LSM6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression EXP pinosylvin results in decreased expression of LSM6 mRNA CTD PMID:23333577 NCBI chr 4:146,175,718...146,191,535
Ensembl chr 4:146,175,703...146,200,000 		JBrowse link
G MCM5 minichromosome maintenance complex component 5 decreases expression EXP pinosylvin results in decreased expression of MCM5 mRNA CTD PMID:23333577 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431 		JBrowse link
G METAP2 methionyl aminopeptidase 2 decreases expression EXP pinosylvin results in decreased expression of METAP2 mRNA CTD PMID:23333577 NCBI chr12:95,474,152...95,515,839
Ensembl chr12:95,473,520...95,515,839 		JBrowse link
G MEX3D mex-3 RNA binding family member D decreases expression EXP pinosylvin results in decreased expression of MEX3D mRNA CTD PMID:23333577 NCBI chr19:1,554,672...1,568,325
Ensembl chr19:1,554,672...1,568,325 		JBrowse link
G MMP7 matrix metallopeptidase 7 multiple interactions EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA CTD PMID:23333577 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MRPL14 mitochondrial ribosomal protein L14 decreases expression EXP pinosylvin results in decreased expression of MRPL14 mRNA CTD PMID:23333577 NCBI chr 6:44,113,451...44,127,452
Ensembl chr 6:44,113,451...44,127,452 		JBrowse link
G MRPL41 mitochondrial ribosomal protein L41 decreases expression EXP pinosylvin results in decreased expression of MRPL41 mRNA CTD PMID:23333577 NCBI chr 9:137,551,879...137,552,555
Ensembl chr 9:137,551,879...137,552,555 		JBrowse link
G MT4 metallothionein 4 increases expression EXP pinosylvin results in increased expression of MT4 mRNA CTD PMID:23333577 NCBI chr16:56,565,073...56,568,957
Ensembl chr16:56,565,073...56,568,957 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression		 EXP [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA
pinosylvin results in decreased expression of MYC protein		 CTD PMID:23333577 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NUP35 nucleoporin 35 decreases expression EXP pinosylvin results in decreased expression of NUP35 mRNA CTD PMID:23333577 NCBI chr 2:183,117,514...183,161,680
Ensembl chr 2:183,117,513...183,161,680 		JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 decreases expression EXP pinosylvin results in decreased expression of OAZ1 mRNA CTD PMID:23333577 NCBI chr19:2,269,486...2,273,488
Ensembl chr19:2,269,509...2,273,492 		JBrowse link
G PCNA proliferating cell nuclear antigen decreases expression EXP pinosylvin results in decreased expression of PCNA mRNA CTD PMID:23333577 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G POLR2J RNA polymerase II subunit J increases expression EXP pinosylvin results in increased expression of POLR2J mRNA CTD PMID:23333577 NCBI chr 7:102,473,128...102,478,922
Ensembl chr 7:102,473,128...102,478,922 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase decreases expression EXP pinosylvin results in decreased expression of PPAT mRNA CTD PMID:23333577 NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615 		JBrowse link
G PTGES2 prostaglandin E synthase 2 decreases expression EXP pinosylvin results in decreased expression of PTGES2 mRNA CTD PMID:23333577 NCBI chr 9:128,120,693...128,128,440
Ensembl chr 9:128,120,693...128,128,462 		JBrowse link
G PTK2 protein tyrosine kinase 2 decreases expression EXP pinosylvin results in decreased expression of PTK2 protein modified form CTD PMID:23333577 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PXMP4 peroxisomal membrane protein 4 increases expression EXP pinosylvin results in increased expression of PXMP4 mRNA CTD PMID:23333577 NCBI chr20:33,702,758...33,720,310
Ensembl chr20:33,702,758...33,720,319 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein decreases expression EXP pinosylvin results in decreased expression of RAD23B mRNA CTD PMID:23333577 NCBI chr 9:107,283,279...107,332,194
Ensembl chr 9:107,283,137...107,332,192 		JBrowse link
G RB1 RB transcriptional corepressor 1 decreases expression EXP pinosylvin results in decreased expression of RB1 protein CTD PMID:23333577 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G RBBP8 RB binding protein 8, endonuclease decreases expression EXP pinosylvin results in decreased expression of RBBP8 mRNA CTD PMID:23333577 NCBI chr18:22,914,139...23,026,486
Ensembl chr18:22,798,261...23,026,488 		JBrowse link
G RBX1 ring-box 1 decreases expression EXP pinosylvin results in decreased expression of RBX1 mRNA CTD PMID:23333577 NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309 		JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP pinosylvin results in decreased expression of RRM2 mRNA CTD PMID:23333577 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725 		JBrowse link
G SEC22B SEC22 homolog B, vesicle trafficking protein increases expression EXP pinosylvin results in increased expression of SEC22B mRNA CTD PMID:23333577 NCBI chr 1:120,150,898...120,176,520
Ensembl chr 1:120,150,898...120,176,520 		JBrowse link
G SERBP1 SERPINE1 mRNA binding protein 1 decreases expression EXP pinosylvin results in decreased expression of SERBP1 mRNA CTD PMID:23333577 NCBI chr 1:67,407,810...67,430,402
Ensembl chr 1:67,407,810...67,430,415 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha increases expression EXP pinosylvin results in increased expression of SGTA mRNA CTD PMID:23333577 NCBI chr19:2,754,715...2,783,273
Ensembl chr19:2,754,715...2,783,362 		JBrowse link
G SLC38A2 solute carrier family 38 member 2 increases expression EXP pinosylvin results in increased expression of SLC38A2 mRNA CTD PMID:23333577 NCBI chr12:46,358,188...46,372,773
Ensembl chr12:46,358,188...46,372,773 		JBrowse link
G SNRPB2 small nuclear ribonucleoprotein polypeptide B2 decreases expression EXP pinosylvin results in decreased expression of SNRPB2 mRNA CTD PMID:23333577 NCBI chr20:16,730,026...16,742,564
Ensembl chr20:16,729,961...16,742,564 		JBrowse link
G SNRPG small nuclear ribonucleoprotein polypeptide G decreases expression EXP pinosylvin results in decreased expression of SNRPG mRNA CTD PMID:23333577 NCBI chr 2:70,281,362...70,293,740
Ensembl chr 2:70,281,362...70,293,740 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase decreases expression EXP pinosylvin results in decreased expression of SRC protein modified form CTD PMID:23333577 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRSF10 serine and arginine rich splicing factor 10 decreases expression EXP pinosylvin results in decreased expression of SRSF10 mRNA CTD PMID:23333577 NCBI chr 1:23,964,347...23,980,327
Ensembl chr 1:23,964,347...23,980,927 		JBrowse link
G SRSF11 serine and arginine rich splicing factor 11 decreases expression EXP pinosylvin results in decreased expression of SRSF11 mRNA CTD PMID:23333577 NCBI chr 1:70,205,696...70,253,052
Ensembl chr 1:70,205,682...70,253,052 		JBrowse link
G SRSF3 serine and arginine rich splicing factor 3 decreases expression EXP pinosylvin results in decreased expression of SFRS3 mRNA CTD PMID:23333577 NCBI chr 6:36,594,362...36,605,600
Ensembl chr 6:36,594,353...36,605,911 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 decreases expression EXP pinosylvin results in decreased expression of SSBP1 mRNA CTD PMID:23333577 NCBI chr 7:141,738,321...141,750,488
Ensembl chr 7:141,738,334...141,787,922 		JBrowse link
G STX6 syntaxin 6 increases expression EXP pinosylvin results in increased expression of STX6 mRNA CTD PMID:23333577 NCBI chr 1:180,972,725...181,022,870
Ensembl chr 1:180,972,712...181,023,121 		JBrowse link
G TBC1D25 TBC1 domain family member 25 increases expression EXP pinosylvin results in increased expression of TBC1D25 mRNA CTD PMID:23333577 NCBI chr  X:48,539,714...48,562,609
Ensembl chr  X:48,539,714...48,562,609 		JBrowse link
G TIMM13 translocase of inner mitochondrial membrane 13 decreases expression EXP pinosylvin results in decreased expression of TIMM13 mRNA CTD PMID:23333577 NCBI chr19:2,425,625...2,427,586
Ensembl chr19:2,425,625...2,427,586 		JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 increases expression EXP pinosylvin results in increased expression of TMED2 mRNA CTD PMID:23333577 NCBI chr12:123,584,552...123,598,582
Ensembl chr12:123,584,533...123,598,582 		JBrowse link
G TMPRSS3 transmembrane serine protease 3 decreases expression EXP pinosylvin results in decreased expression of TMPRSS3 mRNA CTD PMID:23333577 NCBI chr21:42,371,890...42,396,052
Ensembl chr21:42,371,887...42,396,091 		JBrowse link
G TNRC6C trinucleotide repeat containing adaptor 6C decreases expression EXP pinosylvin results in decreased expression of TNRC6C mRNA CTD PMID:23333577 NCBI chr17:77,957,557...78,108,835
Ensembl chr17:77,958,703...78,108,822 		JBrowse link
G TP53 tumor protein p53 increases expression EXP pinosylvin results in increased expression of TP53 protein CTD PMID:23333577 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TSC22D1 TSC22 domain family member 1 increases expression EXP pinosylvin results in increased expression of TSC22D1 mRNA CTD PMID:23333577 NCBI chr13:44,432,143...44,577,344
Ensembl chr13:44,432,143...44,577,147 		JBrowse link
G TUBA1B tubulin alpha 1b decreases expression EXP pinosylvin results in decreased expression of TUBA1B mRNA CTD PMID:23333577 NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397 		JBrowse link
G TUBB tubulin beta class I decreases expression EXP pinosylvin results in decreased expression of TUBB mRNA CTD PMID:23333577 NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538 		JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 decreases expression EXP pinosylvin results in decreased expression of UBE2D1 mRNA CTD PMID:23333577 NCBI chr10:58,335,006...58,370,748
Ensembl chr10:58,334,979...58,370,751 		JBrowse link
G UBXN2A UBX domain protein 2A decreases expression EXP pinosylvin results in decreased expression of UBXN2A mRNA CTD PMID:23333577 NCBI chr 2:23,927,278...24,004,909
Ensembl chr 2:23,927,285...24,004,909 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression EXP pinosylvin results in increased expression of UCHL1 mRNA CTD PMID:23333577 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G USP22 ubiquitin specific peptidase 22 decreases expression EXP pinosylvin results in decreased expression of USP22 mRNA CTD PMID:23333577 NCBI chr17:20,999,596...21,043,419
Ensembl chr17:20,999,596...21,043,760 		JBrowse link
G USP7 ubiquitin specific peptidase 7 increases expression EXP pinosylvin results in increased expression of USP7 mRNA CTD PMID:23333577 NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328 		JBrowse link
G ZBTB44 zinc finger and BTB domain containing 44 decreases expression EXP pinosylvin results in decreased expression of ZBTB44 mRNA CTD PMID:23333577 NCBI chr11:130,226,677...130,314,917
Ensembl chr11:130,226,677...130,314,917 		JBrowse link
G ZNF100 zinc finger protein 100 decreases expression EXP pinosylvin results in decreased expression of ZNF100 mRNA CTD PMID:23333577 NCBI chr19:21,722,771...21,767,579
Ensembl chr19:21,722,771...21,767,579 		JBrowse link
G ZNF207 zinc finger protein 207 decreases expression EXP pinosylvin results in decreased expression of ZNF207 mRNA CTD PMID:23333577 NCBI chr17:32,350,157...32,381,885
Ensembl chr17:32,350,132...32,381,885 		JBrowse link
G ZNF330 zinc finger protein 330 decreases expression EXP pinosylvin results in decreased expression of ZNF330 mRNA CTD PMID:23333577 NCBI chr 4:141,220,535...141,234,697
Ensembl chr 4:141,220,887...141,234,697 		JBrowse link
G ZNF92 zinc finger protein 92 decreases expression EXP pinosylvin results in decreased expression of ZNF92 mRNA CTD PMID:23333577 NCBI chr 7:65,373,855...65,401,136
Ensembl chr 7:65,373,799...65,401,136 		JBrowse link
trans-rhaponticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32662907 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] CTD PMID:32662907 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL10 interleukin 10 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] CTD PMID:32662907 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32662907 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G MMP2 matrix metallopeptidase 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] CTD PMID:32662907 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] CTD PMID:32662907 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] CTD PMID:32662907 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] CTD PMID:32662907 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:32662907 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
trans-stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor affects binding ISO 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G CCNA2 cyclin A2 increases expression EXP 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883 		JBrowse link
G CTSD cathepsin D increases expression EXP 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G ECE1 endothelin converting enzyme 1 decreases activity
decreases expression		 EXP 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA		 CTD PMID:21554123 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EDN1 endothelin 1 decreases secretion
decreases expression		 EXP 4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein
4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA		 CTD PMID:21554123 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G PGR progesterone receptor increases expression EXP 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813 		JBrowse link
G SHBG sex hormone binding globulin affects binding EXP 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
G TFF1 trefoil factor 1 increases expression EXP 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr21:42,362,282...42,366,535
Ensembl chr21:42,362,282...42,366,535 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26503
    chemical entity 26483
      atom 26479
        nonmetal atom 25741
          carbon atom 25623
            organic molecular entity 25623
              olefinic compound 18256
                stilbene 3447
                  trans-stilbene 267
                    N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                    piceatannol + 32
                    pterostilbene 158
                    trans-pinosylvin 105
                    trans-stilben-4-ol 0
                    trans-stilbene-4,4'-diol + 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 26503
    subatomic particle 26479
      composite particle 26479
        hadron 26479
          baryon 26479
            nucleon 26479
              atomic nucleus 26479
                atom 26479
                  main group element atom 26216
                    p-block element atom 26216
                      carbon group element atom 25661
                        carbon atom 25623
                          organic molecular entity 25623
                            organic molecule 25366
                              organic cyclic compound 24419
                                carbocyclic compound 22172
                                  benzenoid aromatic compound 20262
                                    benzenes 19971
                                      stilbene 3447
                                        trans-stilbene 267
                                          N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                                          piceatannol + 32
                                          pterostilbene 158
                                          trans-pinosylvin 105
                                          trans-stilben-4-ol 0
                                          trans-stilbene-4,4'-diol + 10
paths to the root