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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trans-stilbene
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Accession:CHEBI:36007 term browser browse the term
Definition:The trans-isomer of stilbene.
Synonyms:exact_synonym: 1,1'-[(1E)-ethene-1,2-diyl]dibenzene
 related_synonym: (E)-1,2-diphenylethylene;   (E)-stilbene;   1,1'-(E)-ethene-1,2-diyldibenzene;   Formula=C14H12;   InChI=1S/C14H12/c1-3-7-13(8-4-1)11-12-14-9-5-2-6-10-14/h1-12H/b12-11+;   InChIKey=PJANXHGTPQOBST-VAWYXSNFSA-N;   SMILES=c1ccc(cc1)\\C=C\\c1ccccc1;   [(E)-2-phenylethenyl]benzene;   trans-1,2-diphenylethylene;   trans-alpha,beta-diphenylethylene
 xref: Beilstein:1616740;   CAS:103-30-0;   Gmelin:4381;   KNApSAcK:C00037932;   PMID:32201774;   PMID:32662469;   PMID:33564098;   Wikipedia:(E)-Stilbene



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isorhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Hydrogen Peroxide]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO isorhapontigenin results in decreased expression of CCND1 protein CTD PMID:37619952 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased expression of CDH1 protein CTD PMID:37619952 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased localization of CTNNB1 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased phosphorylation of CTNNB1 protein CTD PMID:37619952 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3A protein CTD PMID:37619952 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT3B protein CTD PMID:37619952 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression EXP isorhapontigenin affects the expression of FOS protein CTD PMID:15607907 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in increased phosphorylation of GSK3B protein CTD PMID:37619952 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects activity EXP isorhapontigenin affects the activity of IKBKB protein CTD PMID:15607907 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression EXP isorhapontigenin affects the expression of JUN protein CTD PMID:15607907 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein] CTD PMID:15607907 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:15607907 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP isorhapontigenin inhibits the reaction [AGT protein results in increased phosphorylation of MAPK8 protein] CTD PMID:15607907 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Meg3 maternally expressed 3 multiple interactions ISO isorhapontigenin inhibits the reaction [sodium bichromate results in decreased expression of MEG3] CTD PMID:37619952 NCBI chr 6:128,491,808...128,524,010 JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO isorhapontigenin results in decreased expression of MKI67 protein CTD PMID:37619952 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] inhibits the reaction [CTNNB1 protein modified form binds to NEDD9 protein]; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of and results in decreased localization of NEDD9 protein; [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of NEDD9 mRNA CTD PMID:37619952 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP isorhapontigenin affects the degradation of and affects the phosphorylation of NFKBIA protein CTD PMID:15607907 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of SNAI2 protein CTD PMID:37619952 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
pterostilbene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO pterostilbene results in increased expression of ACADM mRNA CTD PMID:26443543 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of ACOX1 protein CTD PMID:25083823 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased activity of AHR protein]; pterostilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:28279696 PMID:31004704 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of AKR1B1 protein] CTD PMID:21355597 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
multiple interactions
increases phosphorylation
ISO pterostilbene results in decreased expression of AKT1 mRNA
pterostilbene results in decreased phosphorylation of and results in decreased activity of AKT1 protein
pterostilbene results in increased phosphorylation of AKT1 protein
CTD PMID:20152895 PMID:24154491 PMID:31139082 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO pterostilbene results in decreased expression of AMACR mRNA CTD PMID:20152895 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form] CTD PMID:19549798 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]] CTD PMID:34405320 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]] CTD PMID:34405320 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions
ISO pterostilbene results in increased expression of BAD protein
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAD protein]
CTD PMID:20681671 PMID:31139082 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO pterostilbene results in increased expression of BAK1 protein CTD PMID:23313376 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects response to substance
increases expression
multiple interactions
ISO BAX protein affects the susceptibility to pterostilbene
pterostilbene results in increased expression of BAX protein
pterostilbene results in increased expression of BAX mRNA; pterostilbene results in increased expression of BAX protein
pterostilbene inhibits the reaction [sodium arsenite results in increased expression of BAX protein]
CTD PMID:20152895 PMID:20681671 PMID:22572619 PMID:23313376 PMID:24936659 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression
ISO [pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein; pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2 protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene results in increased expression of BCL2 protein
pterostilbene results in decreased expression of BCL2 mRNA; pterostilbene results in decreased expression of BCL2 protein
CTD PMID:18852136 PMID:20152895 PMID:20681671 PMID:24936659 PMID:31139082 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
ISO pterostilbene results in increased expression of BCL2L1 protein
pterostilbene results in decreased expression of BCL2L1 protein
pterostilbene inhibits the reaction [sodium arsenite results in decreased expression of BCL2L1 protein]
CTD PMID:20681671 PMID:23313376 PMID:31139082 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Becn1 beclin 1 multiple interactions ISO BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]] CTD PMID:34405320 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO pterostilbene results in increased expression of BID protein modified form CTD PMID:20681671 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions
increases expression
ISO calcipotriene promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; Calcitriol promotes the reaction [pterostilbene results in increased expression of CAMP protein]; paricalcitol promotes the reaction [pterostilbene results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP mRNA]; pterostilbene promotes the reaction [Calcitriol results in increased expression of CAMP protein]
pterostilbene results in increased expression of CAMP mRNA; pterostilbene results in increased expression of CAMP protein
CTD PMID:24039193 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Casp1 caspase 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]] CTD PMID:34474091 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
increases expression
ISO pterostilbene results in increased cleavage of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP3 protein]; pterostilbene inhibits the reaction [sodium arsenite results in increased expression of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]
pterostilbene results in increased expression of CASP3 mRNA
CTD PMID:20152895 PMID:20681671 PMID:23313376 PMID:24936659 PMID:25341683 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 multiple interactions
increases activity
ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein] CTD PMID:25341683 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp7 caspase 7 multiple interactions ISO pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP7 protein] CTD PMID:33930484 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO pterostilbene results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:20681671 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
increases cleavage
ISO pterostilbene results in increased expression of CASP9 protein
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein]
pterostilbene results in increased cleavage of CASP9 protein
CTD PMID:20152895 PMID:20681671 PMID:25341683 PMID:33930484 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases expression
ISO CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]
pterostilbene results in increased expression of CAT mRNA
pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]
CTD PMID:25341683 PMID:26700463 PMID:34474091 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]
3-methyladenine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; Ammonium Chloride inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; ATG7 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; BECN1 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; Chloroquine inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CCN1 protein]
CTD PMID:34405320 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO
EXP
pterostilbene results in decreased expression of CCND1 protein
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of CCND1 protein]
CTD PMID:19549798 PMID:20398797 PMID:20681671 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression EXP pterostilbene results in decreased expression of CCNE1 protein CTD PMID:20398797 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO pterostilbene inhibits the reaction [Azoxymethane results in decreased expression of CDH1 protein]
pterostilbene results in increased expression of CDH1 protein
CTD PMID:20681671 PMID:23921149 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression EXP pterostilbene results in decreased expression of CDK2 protein CTD PMID:20398797 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP pterostilbene results in decreased expression of CDK4 protein CTD PMID:20398797 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO pterostilbene results in increased expression of CDKN1A protein
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]
CTD PMID:23313376 PMID:34405320 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO pterostilbene results in increased expression of CDKN1B protein CTD PMID:23313376 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions ISO CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN2A protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]] CTD PMID:34405320 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of CPT1A protein CTD PMID:25083823 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crp C-reactive protein multiple interactions ISO [resveratrol co-treated with pterostilbene co-treated with Quercetin co-treated with tocotrienol, delta co-treated with Niacin] results in decreased expression of CRP protein CTD PMID:24319627 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cycs cytochrome c, somatic affects localization
increases expression
ISO pterostilbene affects the localization of CYCS protein
pterostilbene results in increased expression of CYCS mRNA; pterostilbene results in increased expression of CYCS protein
CTD PMID:22450950 PMID:22572619 PMID:26443543 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions
ISO pterostilbene results in decreased expression of CYP1A1 mRNA
pterostilbene results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [pterostilbene results in increased expression of CYP1A1 protein]
CTD PMID:22450950 PMID:31004704 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO pterostilbene results in decreased activity of CYP1A2 protein CTD PMID:16684708 PMID:30394306 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO pterostilbene results in increased expression of CYP2B6 mRNA CTD PMID:30394306 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO pterostilbene results in decreased activity of CYP2C19 protein CTD PMID:30394306 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]
pterostilbene results in increased expression of DDIT3 mRNA; pterostilbene results in increased expression of DDIT3 protein
CTD PMID:22450950 PMID:25341683 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases cleavage ISO pterostilbene results in increased cleavage of DFFA protein CTD PMID:20681671 NCBI chr 5:159,540,715...159,553,639
Ensembl chr 5:159,540,715...159,553,633
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO pterostilbene results in increased expression of DHRS2 mRNA; pterostilbene results in increased expression of DHRS2 protein CTD PMID:24936659 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression
affects localization
ISO pterostilbene results in increased expression of DIABLO protein
pterostilbene affects the localization of DIABLO protein
CTD PMID:22450950 PMID:22572619 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT1 mRNA CTD PMID:26459286 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT3A mRNA CTD PMID:26459286 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO pterostilbene promotes the reaction [resveratrol results in decreased expression of DNMT3B mRNA] CTD PMID:26459286 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Egf epidermal growth factor multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] CTD PMID:19447859 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO pterostilbene results in increased phosphorylation of EIF2A protein CTD PMID:25341683 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form] CTD PMID:19549798 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713
JBrowse link
G Esr1 estrogen receptor 1 increases expression
multiple interactions
ISO pterostilbene results in increased expression of ESR1 protein
[resveratrol co-treated with pterostilbene] results in increased expression of ESR1 mRNA; [resveratrol co-treated with pterostilbene] results in increased expression of ESR1 protein
CTD PMID:27159275 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein] CTD PMID:24361291 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO pterostilbene results in increased expression of FAS protein CTD PMID:20681671 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression ISO pterostilbene results in increased expression of FASL protein CTD PMID:20681671 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase multiple interactions EXP [Dietary Sucrose co-treated with Dietary Fats co-treated with pterostilbene] affects the activity of FASN protein CTD PMID:25083823 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein] CTD PMID:18551458 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fut1 fucosyltransferase 1 increases expression ISO pterostilbene results in increased expression of FUT1 mRNA CTD PMID:22450950 NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO pterostilbene results in increased expression of GDF15 mRNA CTD PMID:22450950 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein] CTD PMID:33930484 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of GPX1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA] CTD PMID:25341683 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of GSK3B protein] CTD PMID:20681671 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
ISO NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]
pterostilbene results in decreased expression of GSR mRNA
CTD PMID:21355597 PMID:25341683 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Resveratrol co-treated with pterostilbene] results in decreased expression of H2AX protein modified form; CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of H2AX protein modified form]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]] CTD PMID:26459286 PMID:34405320 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions
increases phosphorylation
ISO HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter] CTD PMID:26443543 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Hmga1 high mobility group AT-hook 1 multiple interactions ISO CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of HMGA1 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of HMGA1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]
CTD PMID:34405320 PMID:34474091 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]] CTD PMID:34474091 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO pterostilbene results in increased expression of HMOX1 mRNA; pterostilbene results in increased expression of HMOX1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of HMOX1 mRNA; pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 mRNA]; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of HMOX1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]
NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]; pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 protein]
CTD PMID:21355597 PMID:22450950 PMID:25111660 PMID:31139082 PMID:33930484 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M increases expression ISO pterostilbene results in increased expression of HNRNPM mRNA CTD PMID:22450950 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]; CAT protein inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]
pterostilbene results in increased expression of HSPA5 mRNA; pterostilbene results in increased expression of HSPA5 protein
CTD PMID:25341683 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression ISO pterostilbene results in increased expression of HSPA9 mRNA CTD PMID:22450950 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression ISO pterostilbene results in decreased expression of HSPE1 protein CTD PMID:24936659 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Ifng interferon gamma multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IFNG protein]
pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]
CTD PMID:19549798 PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il18 interleukin 18 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]] CTD PMID:34474091 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1A protein]
CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1A mRNA]
CTD PMID:34405320 PMID:34474091 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:19549798 PMID:22698256 PMID:34474091 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL6 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]
CTD PMID:22698256 PMID:34405320 PMID:34474091 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins1 insulin 1 multiple interactions ISO pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein] CTD PMID:26700463 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Itgb8 integrin subunit beta 8 decreases expression
increases expression
ISO pterostilbene results in decreased expression of ITGB8 mRNA
pterostilbene results in increased expression of ITGB8 mRNA
CTD PMID:22450950 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO pterostilbene results in decreased phosphorylation of JAK2 protein CTD PMID:23313376 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein] CTD PMID:18551458 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:26700463 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions
increases expression
ISO MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]
pterostilbene results in increased expression of KLF2 mRNA; pterostilbene results in increased expression of KLF2 protein
CTD PMID:26443543 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of LAMP1 protein] CTD PMID:34405320 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO pterostilbene results in decreased expression of LDLR mRNA CTD PMID:22153697 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]] CTD PMID:34405320 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK1 protein
pterostilbene results in decreased phosphorylation of MAPK1 protein
CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]] CTD PMID:19549798 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pterostilbene results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pterostilbene results in increased phosphorylation of and results in increased activity of MAPK3 protein
pterostilbene results in decreased phosphorylation of MAPK3 protein
CTD PMID:19447859 PMID:24154491 PMID:26138072 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions
increases phosphorylation
ISO MAPK7 protein affects the reaction [pterostilbene results in increased expression of KLF2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein] CTD PMID:26443543 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK8 protein CTD PMID:19447859 PMID:24154491 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene results in decreased phosphorylation of and results in decreased activity of MAPK9 protein CTD PMID:19447859 PMID:24154491 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO pterostilbene results in decreased expression of MCL1 protein CTD PMID:23313376 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased phosphorylation of MLKL protein] CTD PMID:34474091 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein] CTD PMID:20681671 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp28 matrix metallopeptidase 28 multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP26 protein] CTD PMID:20681671 NCBI chr10:68,241,138...68,264,866
Ensembl chr10:68,241,138...68,264,866
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased activity of MMP7 protein]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of MMP7 mRNA]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP2 protein]; pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein] CTD PMID:20681671 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity
multiple interactions
ISO pterostilbene results in decreased expression of MMP9 mRNA
pterostilbene results in decreased activity of MMP9 protein
pterostilbene inhibits the reaction [MMP7 protein results in increased activity of MMP9 protein]
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]
CTD PMID:19447859 PMID:19617202 PMID:20152895 PMID:20681671 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO pterostilbene results in decreased expression of MYC protein CTD PMID:19549798 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]]; NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IL1A protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
affects localization
increases expression
increases phosphorylation
ISO NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of GSR mRNA]]; NFE2L2 protein promotes the reaction [pterostilbene promotes the reaction [Azoxymethane results in increased expression of HMOX1 mRNA]]; pterostilbene inhibits the reaction [NFE2L2 protein binds to KEAP1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; pterostilbene results in increased expression of and results in increased localization of NFE2L2 protein; pterostilbene results in increased phosphorylation of and affects the localization of NFE2L2 protein
pterostilbene affects the localization of NFE2L2 protein
pterostilbene results in increased expression of NFE2L2 protein
pterostilbene results in increased phosphorylation of NFE2L2 protein
2-tert-butylhydroquinone promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; CAT protein inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Pyruvaldehyde affects the localization of NFE2L2 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]
CTD PMID:21355597 PMID:25341683 PMID:26700463 PMID:31139082 PMID:33930484 More... NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein] CTD PMID:18852136 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [pterostilbene co-treated with Quercetin] results in decreased degradation of NFKBIA protein; [pterostilbene co-treated with Quercetin] results in decreased phosphorylation of NFKBIA protein
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]
CTD PMID:18551458 PMID:18852136 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]] CTD PMID:34474091 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]
CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22698256 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO pterostilbene results in increased expression of NQO1 mRNA; pterostilbene results in increased expression of NQO1 protein
[pterostilbene co-treated with kaempferol] results in increased expression of NQO1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of NQO1 protein; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased expression of NQO1 mRNA]; CAT protein inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]
CTD PMID:25111660 PMID:25341683 PMID:31139082 PMID:34474091 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 increases expression ISO pterostilbene results in increased expression of NQO2 mRNA; pterostilbene results in increased expression of NQO2 protein CTD PMID:24936659 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
affects binding
ISO pterostilbene binds to and results in increased activity of NR1I2 protein
pterostilbene binds to NR1I2 protein
CTD PMID:20869355 PMID:30394306 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO pterostilbene binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
ISO pterostilbene results in increased expression of PARP1 protein modified form
pterostilbene inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein]
CTD PMID:19549798 PMID:33930484 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP pterostilbene results in decreased expression of PCNA protein CTD PMID:20398797 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO pterostilbene results in increased expression of PDK4 mRNA CTD PMID:26443543 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression ISO pterostilbene results in decreased expression of PGAM1 protein CTD PMID:24936659 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgr progesterone receptor multiple interactions ISO [resveratrol co-treated with pterostilbene] promotes the reaction [afimoxifene results in decreased expression of PGR mRNA]; [resveratrol co-treated with pterostilbene] promotes the reaction [Estradiol results in increased expression of PGR mRNA] CTD PMID:27159275 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP
ISO
pterostilbene binds to and results in increased activity of PPARA protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]
CTD PMID:15853379 PMID:34474091 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO pterostilbene results in increased expression of PPARGC1A mRNA CTD PMID:26443543 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions
increases phosphorylation
ISO PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of HDAC5 protein]; PRKAA1 protein affects the reaction [pterostilbene results in increased phosphorylation of MAPK7 protein]
pterostilbene results in increased phosphorylation of PRKAA1 protein
CTD PMID:26443543 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of and results in increased activity of PRKCB protein] CTD PMID:21355597 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Psme3 proteasome activator subunit 3 decreases expression ISO pterostilbene results in decreased expression of PSME3 protein CTD PMID:24936659 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [Azoxymethane results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]
CTD PMID:18551458 PMID:19549798 PMID:20681671 PMID:21355597 PMID:22842666 More... NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]] CTD PMID:34474091 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP pterostilbene results in decreased expression of RB1 protein CTD PMID:20398797 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [pterostilbene co-treated with Quercetin] affects the localization of RELA protein; [pterostilbene co-treated with Quercetin] results in decreased activity of [NFKB1 protein binds to RELA protein]; RELA protein affects the reaction [[pterostilbene co-treated with Quercetin] results in decreased expression of BCL2 protein]
pterostilbene inhibits the reaction [Azoxymethane results in increased phosphorylation of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]
CTD PMID:18551458 PMID:18852136 PMID:21355597 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK1 protein] CTD PMID:34474091 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO NFATC4 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]]; pterostilbene inhibits the reaction [Ethanol promotes the reaction [RIPK1 protein binds to RIPK3 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased expression of RIPK3 protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased activity of CAT protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMOX1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NFE2L2 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of NQO1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of PPARA protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CASP1 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL1B protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL6 mRNA]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of PYCARD protein]]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]] CTD PMID:34474091 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO pterostilbene results in decreased expression of RPS12 protein CTD PMID:24936659 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO pterostilbene results in increased expression of SARS1 mRNA CTD PMID:22450950 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of ATG5 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of BECN1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN1A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of CDKN2A protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of H2AX protein modified form]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of HMGA1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of MAP1LC3B protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in decreased expression of SESN2 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of IFNG protein]]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]] CTD PMID:34405320 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 mRNA; [resveratrol co-treated with pterostilbene] results in decreased expression of SIRT1 protein CTD PMID:26459286 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt2 sirtuin 2 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in decreased expression of SIRT2 protein]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of and results in increased acetylation of NFATC4 protein]]; SIRT2 protein affects the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of NFATC4 protein]] CTD PMID:34474091 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein] CTD PMID:22865646 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO pterostilbene results in decreased expression of SNAI1 protein CTD PMID:23921149 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO [pterostilbene co-treated with kaempferol] results in increased expression of SOD1 protein; [pterostilbene co-treated with Quercetin] results in increased expression of SOD1 protein; pterostilbene inhibits the reaction [Pyruvaldehyde results in decreased expression of SOD1 mRNA]
pterostilbene results in increased expression of SOD1 protein
CTD PMID:25111660 PMID:33930484 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
increases activity
ISO [pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein; HDAC5 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; MAPK7 protein affects the reaction [pterostilbene results in increased expression of SOD2 mRNA]; pterostilbene inhibits the reaction [HDAC5 protein binds to SOD2 promoter]; pterostilbene promotes the reaction [KLF2 protein binds to SOD2 promoter]; pterostilbene results in increased expression of and results in increased activity of SOD2 protein; SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein]
pterostilbene results in increased expression of SOD2 protein
ESR2 gene mutant form inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [pterostilbene results in increased expression of SOD2 protein]
pterostilbene results in increased activity of SOD2 protein
CTD PMID:18852136 PMID:22450950 PMID:22572619 PMID:24361291 PMID:26443543 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO SP1 protein affects the reaction [[pterostilbene co-treated with Quercetin] results in increased expression of SOD2 protein] CTD PMID:18852136 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO bafilomycin A1 inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; Cycloheximide promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]]; pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] CTD PMID:34405320 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
decreases phosphorylation
decreases activity
ISO pterostilbene results in decreased expression of STAT3 protein modified form
pterostilbene results in decreased phosphorylation of STAT3 protein
pterostilbene results in decreased activity of STAT3 protein
CTD PMID:22450950 PMID:23313376 PMID:26138072 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO pterostilbene results in increased phosphorylation of STK11 protein CTD PMID:26443543 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO pterostilbene inhibits the reaction [Ethanol results in increased expression of TERF1 protein] CTD PMID:34405320 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tert telomerase reverse transcriptase decreases expression
multiple interactions
ISO pterostilbene results in decreased expression of TERT mRNA; pterostilbene results in decreased expression of TERT protein
pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT mRNA]; pterostilbene inhibits the reaction [Ethanol results in decreased expression of TERT protein]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT mRNA]; Resveratrol promotes the reaction [pterostilbene results in decreased expression of TERT protein]
CTD PMID:26459286 PMID:34405320 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]; MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ATF2 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of ELK1 protein modified form]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 mRNA]; pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of TNF mRNA]]
pterostilbene inhibits the reaction [[Lipopolysaccharides co-treated with Thioglycolates] results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pterostilbene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; SESN2 protein promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased secretion of TNF protein]]
CTD PMID:19549798 PMID:22698256 PMID:23731018 PMID:34405320 PMID:34474091 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO pterostilbene results in increased expression of TP53 mRNA CTD PMID:20152895 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression ISO pterostilbene results in decreased expression of TPT1 protein CTD PMID:24936659 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
decreases activity
multiple interactions
ISO UGT1A1 protein results in increased glucuronidation of pterostilbene
pterostilbene results in decreased activity of UGT1A1 protein
pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
CTD PMID:23965644 PMID:31812603 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation
multiple interactions
decreases activity
ISO UGT1A3 protein results in increased glucuronidation of pterostilbene
pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A3 protein
CTD PMID:23965644 PMID:31812603 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
decreases activity
ISO pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A6 protein
CTD PMID:31812603 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects glucuronidation
multiple interactions
decreases activity
ISO UGT1A9 protein affects the glucuronidation of pterostilbene
pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
pterostilbene results in decreased activity of UGT1A9 protein
CTD PMID:23965644 PMID:31812603 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity
multiple interactions
ISO pterostilbene results in decreased activity of UGT2B7 protein
pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]
CTD PMID:31812603 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Umod uromodulin multiple interactions ISO pterostilbene inhibits the reaction [potassium oxonate results in increased expression of UMOD protein] CTD PMID:22865646 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Zfp488 zinc finger protein 488 decreases expression ISO pterostilbene results in decreased expression of ZNF488 mRNA CTD PMID:22450950 NCBI chr16:9,283,039...9,293,681
Ensembl chr16:9,283,043...9,293,671
JBrowse link
rhapontigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases activity ISO rhapontigenin analog results in increased activity of ESR1 protein CTD PMID:17935960 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity
multiple interactions
ISO rhapontigenin analog results in increased activity of ESR2 protein
Fulvestrant inhibits the reaction [rhapontigenin analog results in increased activity of ESR2 protein]
CTD PMID:17692514 PMID:17935960 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Tf transferrin multiple interactions ISO rhapontigenin analog inhibits the reaction [Lipopolysaccharides results in increased activity of TF protein] CTD PMID:16507316 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
trans-pinosylvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 decreases expression ISO pinosylvin results in decreased expression of ABCB10 mRNA CTD PMID:23333577 NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753
JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 decreases expression ISO pinosylvin results in decreased expression of ABCE1 mRNA CTD PMID:23333577 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO pinosylvin results in decreased expression of ARHGAP29 mRNA CTD PMID:23333577 NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028
JBrowse link
G Art1 ADP-ribosyltransferase 1 increases expression ISO pinosylvin results in increased expression of ART1 mRNA CTD PMID:23333577 NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172
JBrowse link
G Bag2 BAG cochaperone 2 decreases expression ISO pinosylvin results in decreased expression of BAG2 mRNA CTD PMID:23333577 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721
JBrowse link
G Bcap29 B-cell receptor-associated protein 29 decreases expression ISO pinosylvin results in decreased expression of BCAP29 mRNA CTD PMID:23333577 NCBI chr 6:48,182,702...48,222,698
Ensembl chr 6:48,182,706...48,222,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA CTD PMID:23333577 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA CTD PMID:23333577 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cbx3 chromobox 3 decreases expression ISO pinosylvin results in decreased expression of CBX3 mRNA CTD PMID:23333577 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO pinosylvin results in decreased expression of CCNA2 protein CTD PMID:23333577 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA
pinosylvin results in decreased expression of CCND1 protein
CTD PMID:23333577 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO pinosylvin results in decreased expression of CCNE1 protein CTD PMID:23333577 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO pinosylvin results in decreased expression of CDCA2 mRNA CTD PMID:23333577 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO pinosylvin results in decreased expression of CDK2 protein CTD PMID:23333577 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk2ap1 cyclin-dependent kinase 2 associated protein 1 decreases expression ISO pinosylvin results in decreased expression of CDK2AP1 mRNA CTD PMID:23333577 NCBI chr12:32,249,752...32,258,483
Ensembl chr12:32,249,747...32,258,479
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO pinosylvin results in decreased expression of CDK4 protein CTD PMID:23333577 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk8 cyclin-dependent kinase 8 decreases expression ISO pinosylvin results in decreased expression of CDK8 mRNA CTD PMID:23333577 NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO pinosylvin results in increased expression of CDKN1A mRNA CTD PMID:23333577 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cenpf centromere protein F decreases expression ISO pinosylvin results in decreased expression of CENPF mRNA CTD PMID:23333577 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO pinosylvin results in increased expression of CEP290 mRNA CTD PMID:23333577 NCBI chr 7:35,310,071...35,399,388
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B decreases expression ISO pinosylvin results in decreased expression of CHAF1B mRNA CTD PMID:23333577 NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070
JBrowse link
G Chd1 chromodomain helicase DNA binding protein 1 increases expression ISO pinosylvin results in increased expression of CHD1 mRNA CTD PMID:23333577 NCBI chr 1:56,661,743...56,729,119
Ensembl chr 1:56,664,054...56,728,125
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO pinosylvin results in decreased expression of CKS2 mRNA CTD PMID:23333577 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression ISO pinosylvin results in decreased expression of COX5A mRNA CTD PMID:23333577 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C decreases expression ISO pinosylvin results in decreased expression of COX7C mRNA CTD PMID:23333577 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BIRC5 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of BMP4 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of CCND1 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA; [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA; pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein CTD PMID:23333577 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dchs2 dachsous cadherin-related 2 increases expression ISO pinosylvin results in increased expression of DCHS2 mRNA CTD PMID:23333577 NCBI chr 2:168,478,298...168,685,802
Ensembl chr 2:168,478,826...168,682,732
JBrowse link
G Dhx15 DEAH-box helicase 15 decreases expression ISO pinosylvin results in decreased expression of DHX15 mRNA CTD PMID:23333577 NCBI chr14:58,787,147...58,825,083
Ensembl chr14:58,787,127...58,825,088
JBrowse link
G Dsg1 desmoglein 1 decreases expression ISO pinosylvin results in decreased expression of DSG1 mRNA CTD PMID:23333577 NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443
JBrowse link
G Eno1 enolase 1 decreases expression ISO pinosylvin results in decreased expression of ENO1 mRNA CTD PMID:23333577 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression ISO pinosylvin results in increased expression of ERCC1 mRNA CTD PMID:23333577 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Etfb electron transfer flavoprotein subunit beta increases expression ISO pinosylvin results in increased expression of ETFB mRNA CTD PMID:23333577 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Fbxo8 F-box protein 8 increases expression ISO pinosylvin results in increased expression of FBXO8 mRNA CTD PMID:23333577 NCBI chr16:33,665,305...33,711,215
Ensembl chr16:33,665,306...33,711,272
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO pinosylvin results in decreased expression of FDPS mRNA CTD PMID:23333577 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fh fumarate hydratase decreases expression ISO pinosylvin results in decreased expression of FH mRNA CTD PMID:23333577 NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO pinosylvin results in increased expression of FTH1 mRNA CTD PMID:23333577 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO pinosylvin results in increased expression of GADD45A mRNA CTD PMID:23333577 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO pinosylvin results in increased expression of GDF15 mRNA; pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression ISO pinosylvin results in decreased expression of GNAI1 mRNA CTD PMID:23333577 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 decreases expression ISO pinosylvin results in decreased expression of GTF2H5 mRNA CTD PMID:23333577 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G H3f3b H3.3 histone B decreases expression ISO pinosylvin results in decreased expression of H3-3B mRNA CTD PMID:23333577 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
Ensembl chr13:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase increases expression ISO pinosylvin results in increased expression of HAL mRNA CTD PMID:23333577 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hmox2 heme oxygenase 2 increases expression ISO pinosylvin results in increased expression of HMOX2 mRNA CTD PMID:23333577 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO pinosylvin results in decreased expression of HSP90AB1 mRNA CTD PMID:23333577 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions
decreases expression
ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of ID2 mRNA
pinosylvin results in decreased expression of ID2 mRNA
CTD PMID:23333577 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO pinosylvin results in decreased expression of IDI1 mRNA CTD PMID:23333577 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Il1rap interleukin 1 receptor accessory protein decreases expression ISO pinosylvin results in decreased expression of IL1RAP mRNA CTD PMID:23333577 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 increases expression ISO pinosylvin results in increased expression of IRF2BP1 mRNA CTD PMID:23333577 NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530
JBrowse link
G Jag1 jagged canonical Notch ligand 1 increases expression ISO pinosylvin results in increased expression of JAG1 mRNA CTD PMID:23333577 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Kbtbd6 kelch repeat and BTB domain containing 6 decreases expression ISO pinosylvin results in decreased expression of KBTBD6 mRNA CTD PMID:23333577 NCBI chr15:54,848,285...54,850,042
Ensembl chr15:54,848,446...54,850,453
JBrowse link
G Lrrc25 leucine rich repeat containing 25 increases expression ISO pinosylvin results in increased expression of LRRC25 mRNA CTD PMID:23333577 NCBI chr16:18,806,888...18,813,723
Ensembl chr16:18,806,890...18,813,671
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO pinosylvin results in decreased expression of LSM6 mRNA CTD PMID:23333577 NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO pinosylvin results in decreased expression of MCM5 mRNA CTD PMID:23333577 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Metap2 methionyl aminopeptidase 2 decreases expression ISO pinosylvin results in decreased expression of METAP2 mRNA CTD PMID:23333577 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Mex3d mex-3 RNA binding family member D decreases expression ISO pinosylvin results in decreased expression of MEX3D mRNA CTD PMID:23333577 NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MMP7 mRNA CTD PMID:23333577 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 decreases expression ISO pinosylvin results in decreased expression of MRPL14 mRNA CTD PMID:23333577 NCBI chr 9:15,302,840...15,315,195
Ensembl chr 9:15,302,427...15,315,267
JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 decreases expression ISO pinosylvin results in decreased expression of MRPL41 mRNA CTD PMID:23333577 NCBI chr 3:7,780,658...7,781,576
Ensembl chr 3:7,779,143...7,782,818
JBrowse link
G Mt4 metallothionein 4 increases expression ISO pinosylvin results in increased expression of MT4 mRNA CTD PMID:23333577 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
ISO [pinosylvin affects the localization of and results in decreased activity of CTNNB1 protein] which results in decreased expression of MYC mRNA
pinosylvin results in decreased expression of MYC protein
CTD PMID:23333577 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nup35 nucleoporin 35 decreases expression ISO pinosylvin results in decreased expression of NUP35 mRNA CTD PMID:23333577 NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130
JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 decreases expression ISO pinosylvin results in decreased expression of OAZ1 mRNA CTD PMID:23333577 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO pinosylvin results in decreased expression of PCNA mRNA CTD PMID:23333577 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Polr2j RNA polymerase II subunit J increases expression ISO pinosylvin results in increased expression of POLR2J mRNA CTD PMID:23333577 NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase decreases expression ISO pinosylvin results in decreased expression of PPAT mRNA CTD PMID:23333577 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Ptges2 prostaglandin E synthase 2 decreases expression ISO pinosylvin results in decreased expression of PTGES2 mRNA CTD PMID:23333577 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO pinosylvin results in decreased expression of PTK2 protein modified form CTD PMID:23333577 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 increases expression ISO pinosylvin results in increased expression of PXMP4 mRNA CTD PMID:23333577 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein decreases expression ISO pinosylvin results in decreased expression of RAD23B mRNA CTD PMID:23333577 NCBI chr 5:70,090,232...70,128,340
Ensembl chr 5:70,090,232...70,128,319
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO pinosylvin results in decreased expression of RB1 protein CTD PMID:23333577 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease decreases expression ISO pinosylvin results in decreased expression of RBBP8 mRNA CTD PMID:23333577 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rbx1 ring-box 1 decreases expression ISO pinosylvin results in decreased expression of RBX1 mRNA CTD PMID:23333577 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO pinosylvin results in decreased expression of RRM2 mRNA CTD PMID:23333577 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Sec22b SEC22 homolog B, vesicle trafficking protein increases expression ISO pinosylvin results in increased expression of SEC22B mRNA CTD PMID:23333577 NCBI chr 2:185,500,029...185,520,811
Ensembl chr 2:185,500,004...185,522,026
JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 decreases expression ISO pinosylvin results in decreased expression of SERBP1 mRNA CTD PMID:23333577 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha increases expression ISO pinosylvin results in increased expression of SGTA mRNA CTD PMID:23333577 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Slc38a2 solute carrier family 38, member 2 increases expression ISO pinosylvin results in increased expression of SLC38A2 mRNA CTD PMID:23333577 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 decreases expression ISO pinosylvin results in decreased expression of SNRPB2 mRNA CTD PMID:23333577 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G decreases expression ISO pinosylvin results in decreased expression of SNRPG mRNA CTD PMID:23333577 NCBI chr 4:118,812,278...118,819,827
Ensembl chr 4:118,812,252...118,819,826
Ensembl chr  X:118,812,252...118,819,826
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases expression ISO pinosylvin results in decreased expression of SRC protein modified form CTD PMID:23333577 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srsf10 serine and arginine rich splicing factor 10 decreases expression ISO pinosylvin results in decreased expression of SRSF10 mRNA CTD PMID:23333577 NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
JBrowse link
G Srsf11 serine and arginine rich splicing factor 11 decreases expression ISO pinosylvin results in decreased expression of SRSF11 mRNA CTD PMID:23333577 NCBI chr 2:247,074,623...247,101,460
Ensembl chr 2:247,074,631...247,101,425
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO pinosylvin results in decreased expression of SFRS3 mRNA CTD PMID:23333577 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 decreases expression ISO pinosylvin results in decreased expression of SSBP1 mRNA CTD PMID:23333577 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Stx6 syntaxin 6 increases expression ISO pinosylvin results in increased expression of STX6 mRNA CTD PMID:23333577 NCBI chr13:67,332,329...67,378,580
Ensembl chr13:67,332,314...67,378,576
JBrowse link
G Tbc1d25 TBC1 domain family, member 25 increases expression ISO pinosylvin results in increased expression of TBC1D25 mRNA CTD PMID:23333577 NCBI chr  X:14,314,095...14,339,171
Ensembl chr  X:14,314,414...14,338,275
JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 decreases expression ISO pinosylvin results in decreased expression of TIMM13 mRNA CTD PMID:23333577 NCBI chr 7:8,809,069...8,810,172
Ensembl chr 7:8,809,058...8,809,910
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression ISO pinosylvin results in increased expression of TMED2 mRNA CTD PMID:23333577 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tmprss3 transmembrane serine protease 3 decreases expression ISO pinosylvin results in decreased expression of TMPRSS3 mRNA CTD PMID:23333577 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363
JBrowse link
G Tnrc6c trinucleotide repeat containing adaptor 6C decreases expression ISO pinosylvin results in decreased expression of TNRC6C mRNA CTD PMID:23333577 NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194
JBrowse link
G Tp53 tumor protein p53 increases expression ISO pinosylvin results in increased expression of TP53 protein CTD PMID:23333577 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO pinosylvin results in increased expression of TSC22D1 mRNA CTD PMID:23333577 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression ISO pinosylvin results in decreased expression of TUBA1B mRNA CTD PMID:23333577 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO pinosylvin results in decreased expression of TUBB mRNA CTD PMID:23333577 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Ube2d1 ubiquitin-conjugating enzyme E2D 1 decreases expression ISO pinosylvin results in decreased expression of UBE2D1 mRNA CTD PMID:23333577 NCBI chr20:17,309,315...17,343,770
Ensembl chr20:17,309,315...17,342,295
JBrowse link
G Ubxn2a UBX domain protein 2A decreases expression ISO pinosylvin results in decreased expression of UBXN2A mRNA CTD PMID:23333577 NCBI chr 6:27,884,364...27,912,767
Ensembl chr 6:27,884,680...27,912,649
Ensembl chr20:27,884,680...27,912,649
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression ISO pinosylvin results in increased expression of UCHL1 mRNA CTD PMID:23333577 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Usp22 ubiquitin specific peptidase 22 decreases expression ISO pinosylvin results in decreased expression of USP22 mRNA CTD PMID:23333577 NCBI chr10:45,828,619...45,855,468
Ensembl chr10:45,828,622...45,855,497
JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression ISO pinosylvin results in increased expression of USP7 mRNA CTD PMID:23333577 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355
JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 decreases expression ISO pinosylvin results in decreased expression of ZBTB44 mRNA CTD PMID:23333577 NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163
JBrowse link
G Zfp207 zinc finger protein 207 decreases expression ISO pinosylvin results in decreased expression of ZNF207 mRNA CTD PMID:23333577 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386
JBrowse link
G Zfp330 zinc finger protein 330 decreases expression ISO pinosylvin results in decreased expression of ZNF330 mRNA CTD PMID:23333577 NCBI chr19:25,313,655...25,324,958
Ensembl chr19:25,313,655...25,324,958
JBrowse link
trans-rhaponticin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:32662907 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] CTD PMID:32662907 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il10 interleukin 10 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] CTD PMID:32662907 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Ins1 insulin 1 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:32662907 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] CTD PMID:32662907 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] CTD PMID:32662907 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] CTD PMID:32662907 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] CTD PMID:32662907 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] CTD PMID:32662907 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] CTD PMID:32662907 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
trans-stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression
ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA
CTD PMID:21554123 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression
ISO 4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein
4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA
CTD PMID:21554123 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      atom 19872
        nonmetal atom 19794
          carbon atom 19748
            organic molecular entity 19748
              olefinic compound 16965
                stilbene 3404
                  trans-stilbene 258
                    N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                    piceatannol + 32
                    pterostilbene 152
                    trans-pinosylvin 102
                    trans-stilben-4-ol 0
                    trans-stilbene-4,4'-diol + 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                carbocyclic compound 18579
                                  benzenoid aromatic compound 18003
                                    benzenes 17868
                                      stilbene 3404
                                        trans-stilbene 258
                                          N-(trans-4'-nitro-4-stilbenyl)-N-methyl-5-aminopentanoic acid 0
                                          piceatannol + 32
                                          pterostilbene 152
                                          trans-pinosylvin 102
                                          trans-stilben-4-ol 0
                                          trans-stilbene-4,4'-diol + 10
paths to the root