serotonergic agonist - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	serotonergic agonist	go back to main search page
Accession:	CHEBI:35941	browse the term
Definition:	An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Synonyms:	related_synonym:	5-HT agonist; 5-hydroxytryptamine agonist; serotonergic agonists; serotonin agonist; serotonin agonists

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Rat (1023) Mouse (1011) Human (1026) Chinchilla (0) Bonobo (0) Dog (2) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (1023)

(S)-fenfluramine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

solute carrier family 22 member 2

multiple interactions

Dexfenfluramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

G

solute carrier family 6 member 4

affects activity

Dexfenfluramine affects the activity of SLC6A4 protein

NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384

1-(3-(trifluoromethyl)phenyl)piperazine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetyl-CoA acetyltransferase 2

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

betaine-homocysteine S-methyltransferase

decreases expression

1-(3-trifluoromethylphenyl)piperazine results in decreased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

cytochrome P450, family 51

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of CYP51 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

1-(3-trifluoromethylphenyl)piperazine results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

estrogen receptor 1

multiple interactions

1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [Estradiol binds to ESR1 protein]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

fatty acid desaturase 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid synthase

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

farnesyl diphosphate farnesyl transferase 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

gamma-aminobutyric acid type A receptor subunit alpha 1

multiple interactions

1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit gamma 2

multiple interactions

1-(3-trifluoromethylphenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

glycoprotein nmb

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

isopentenyl-diphosphate delta isomerase 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

methylsterol monooxygenase 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of MSMO1 mRNA

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

proprotein convertase subtilisin/kexin type 9

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of PCSK9 mRNA

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

progesterone receptor

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of PGR mRNA

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

Ras-related GTP binding D

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of RRAGD mRNA

NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356

G

squalene epoxidase

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

trefoil factor 1

increases expression

1-(3-trifluoromethylphenyl)piperazine results in increased expression of TFF1 mRNA

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

1-(3-chlorophenyl)piperazine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily d, polypeptide 4

affects metabolic processing
multiple interactions

CYP2D6 protein affects the metabolism of 1-(3-chlorophenyl)piperazine
Quinidine inhibits the reaction [CYP2D6 protein affects the metabolism of 1-(3-chlorophenyl)piperazine]

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

1-(3-chlorophenyl)piperazine results in increased expression of FOS protein
8-(5-(5-amino-2,4-dimethoxyphenyl)-5-oxopentyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione inhibits the reaction [1-(3-chlorophenyl)piperazine results in increased expression of FOS protein]

PMID:11298663 PMID:28186389

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

gamma-aminobutyric acid type B receptor subunit 2

multiple interactions

1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]

NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104

G

gamma-aminobutyric acid type A receptor subunit alpha 1

multiple interactions

1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; 3,4-Methylenedioxyamphetamine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

PMID:21729720 PMID:23266428 PMID:26344803

NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; 3,4-Methylenedioxyamphetamine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

PMID:23266428 PMID:26344803

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit gamma 2

multiple interactions

1-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]; 1-(3-chlorophenyl)piperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; 3,4-Methylenedioxyamphetamine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

PMID:21729720 PMID:23266428 PMID:26344803

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

5-hydroxytryptamine receptor 1A

multiple interactions

[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 2A

increases response to substance
multiple interactions
affects response to substance

HTR2A gene SNP results in increased susceptibility to 1-(3-chlorophenyl)piperazine
1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2A protein
HTR2A protein affects the susceptibility to 1-(3-chlorophenyl)piperazine

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

5-hydroxytryptamine receptor 2C

multiple interactions

[1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine

NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287

G

leptin

multiple interactions

1-(3-chlorophenyl)piperazine inhibits the reaction [Corticosterone results in decreased expression of LEP protein]; 8-(5-(5-amino-2,4-dimethoxyphenyl)-5-oxopentyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione inhibits the reaction [1-(3-chlorophenyl)piperazine inhibits the reaction [Corticosterone results in decreased expression of LEP protein]]

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [1-(3-chlorophenyl)piperazine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

phospholipase C beta 1

increases expression

1-(3-chlorophenyl)piperazine results in increased expression of PLCB1 mRNA; 1-(3-chlorophenyl)piperazine results in increased expression of PLCB1 protein

NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869

G

prolactin

multiple interactions
increases expression

Cocaine inhibits the reaction [1-(3-chlorophenyl)piperazine results in increased expression of PRL protein]

PMID:9598218 PMID:16418827

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

solute carrier family 6 member 4

affects response to substance

SLC6A4 protein affects the susceptibility to 1-(3-chlorophenyl)piperazine

NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384

1-benzylpiperazine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate-semialdehyde synthase

decreases expression

N-benzylpiperazine results in decreased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

acetyl-CoA acetyltransferase 2

increases expression

N-benzylpiperazine results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

acyl-CoA synthetase long-chain family member 3

increases expression

N-benzylpiperazine results in increased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

N-benzylpiperazine results in decreased expression of ACSM5 mRNA

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

beta-1,4-galactosyltransferase 1

increases expression

N-benzylpiperazine results in increased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

gamma-butyrobetaine hydroxylase 1

decreases expression

N-benzylpiperazine results in decreased expression of BBOX1 mRNA

NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458

G

betaine-homocysteine S-methyltransferase

decreases expression

N-benzylpiperazine results in decreased expression of BHMT mRNA

NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742

G

betaine-homocysteine S-methyltransferase 2

decreases expression

N-benzylpiperazine results in decreased expression of BHMT2 mRNA

NCBI chr 2:24,895,525...24,912,475
Ensembl chr 2:24,895,533...24,912,475

G

Cdk5 and Abl enzyme substrate 1

increases expression

N-benzylpiperazine results in increased expression of CABLES1 mRNA

NCBI chr18:3,076,556...3,181,181
Ensembl chr18:3,075,524...3,181,181

G

catalase

increases activity

1-benzylpiperazine results in increased activity of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

cysteine and glycine rich protein 3

increases expression

N-benzylpiperazine results in increased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cytochrome P450, family 2, subfamily a, polypeptide 1

decreases expression

N-benzylpiperazine results in decreased expression of CYP2A1 mRNA

NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

N-benzylpiperazine results in decreased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 4, subfamily a, polypeptide 1

decreases expression

N-benzylpiperazine results in decreased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily a, polypeptide 3

decreases expression

N-benzylpiperazine results in decreased expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 4, subfamily f, polypeptide 4

decreases expression

N-benzylpiperazine results in decreased expression of CYP4F4 mRNA

NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506

G

cytochrome P450, family 51

increases expression

N-benzylpiperazine results in increased expression of CYP51 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
Ensembl chr 6:30,036,865...30,055,410

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

N-benzylpiperazine results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dihydropyrimidine dehydrogenase

decreases expression

N-benzylpiperazine results in decreased expression of DPYD mRNA

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

dihydropyrimidinase-like 2

increases expression

N-benzylpiperazine results in increased expression of DPYSL2 mRNA

NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829

G

endonuclease/exonuclease/phosphatase family domain containing 1

increases expression

N-benzylpiperazine results in increased expression of EEPD1 mRNA

NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

decreases expression

N-benzylpiperazine results in decreased expression of EHHADH mRNA

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

fatty acid desaturase 1

increases expression

N-benzylpiperazine results in increased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid synthase

increases expression

N-benzylpiperazine results in increased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fructose-bisphosphatase 1

decreases expression

N-benzylpiperazine results in decreased expression of FBP1 mRNA

NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071

G

farnesyl diphosphate farnesyl transferase 1

increases expression

N-benzylpiperazine results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

increases expression

N-benzylpiperazine results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

folliculin

increases expression

N-benzylpiperazine results in increased expression of FLCN mRNA

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

G

formimidoyltransferase cyclodeaminase

decreases expression

N-benzylpiperazine results in decreased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

N-benzylpiperazine results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

gamma-aminobutyric acid type A receptor subunit alpha 1

multiple interactions

1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251

G

gamma-aminobutyric acid type A receptor subunit gamma 2

multiple interactions

1-benzylpiperazine analog inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 1-benzylpiperazine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

glycoprotein nmb

increases expression

N-benzylpiperazine results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

glycogen synthase 2

decreases expression

N-benzylpiperazine results in decreased expression of GYS2 mRNA

NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228

G

hydroxyacid oxidase 2

decreases expression

N-benzylpiperazine results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

N-benzylpiperazine results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

N-benzylpiperazine results in increased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

N-benzylpiperazine results in decreased expression of HMGCS2 mRNA

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

isopentenyl-diphosphate delta isomerase 1

increases expression

N-benzylpiperazine results in increased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

interleukin 1 receptor type 2

increases expression

N-benzylpiperazine results in increased expression of IL1R2 mRNA

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

G

insulin induced gene 1

increases expression

N-benzylpiperazine results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

kynureninase

decreases expression

N-benzylpiperazine results in decreased expression of KYNU mRNA

NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488

G

minichromosome maintenance complex component 6

increases expression

N-benzylpiperazine results in increased expression of MCM6 mRNA

NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960

G

malate dehydrogenase 1

decreases expression

N-benzylpiperazine results in decreased expression of MDH1 mRNA

NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925

G

methylsterol monooxygenase 1

increases expression

N-benzylpiperazine results in increased expression of MSMO1 mRNA

NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016

G

N-myc downstream regulated 1

increases expression

N-benzylpiperazine results in increased expression of NDRG1 mRNA

NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880

G

nuclear receptor subfamily 1, group I, member 3

decreases expression

N-benzylpiperazine results in decreased expression of NR1I3 mRNA

NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906

G

neuregulin 1

increases expression

N-benzylpiperazine results in increased expression of NRG1 mRNA

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

proprotein convertase subtilisin/kexin type 9

increases expression

N-benzylpiperazine results in increased expression of PCSK9 mRNA

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

increases expression

N-benzylpiperazine results in increased expression of PDP2 mRNA

NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074

G

proliferation and apoptosis adaptor protein 15

increases expression

N-benzylpiperazine results in increased expression of PEA15 mRNA

NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499

G

progesterone receptor

increases expression

1-benzylpiperazine results in increased expression of PGR mRNA

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

RAB30, member RAS oncogene family

increases expression

N-benzylpiperazine results in increased expression of RAB30 mRNA

NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181

G

RAB32, member RAS oncogene family

increases expression

N-benzylpiperazine results in increased expression of RAB32 mRNA

NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934

G

ras homolog family member Q

increases expression

N-benzylpiperazine results in increased expression of RHOQ mRNA

NCBI chr 6:7,613,632...7,652,047
Ensembl chr 1:106,622,141...106,623,699

G

ring finger protein 145

increases expression

N-benzylpiperazine results in increased expression of RNF145 mRNA

NCBI chr10:29,006,391...29,050,788
Ensembl chr10:29,011,548...29,050,781

G

Ras-related GTP binding D

increases expression

N-benzylpiperazine results in increased expression of RRAGD mRNA

NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356

G

solute carrier family 10 member 1

decreases expression

N-benzylpiperazine results in decreased expression of SLC10A1 mRNA

NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 38, member 7

increases expression

N-benzylpiperazine results in increased expression of SLC38A7 mRNA

NCBI chr19:9,209,203...9,225,472
Ensembl chr19:9,209,257...9,225,454

G

solute carrier family 39 member 10

increases expression

N-benzylpiperazine results in increased expression of SLC39A10 mRNA

NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325

G

solute carrier family 6 member 6

increases expression

N-benzylpiperazine results in increased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

solute carrier organic anion transporter family, member 1a4

decreases expression

N-benzylpiperazine results in decreased expression of SLCO1A2 mRNA

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

superoxide dismutase 1

increases activity

1-benzylpiperazine results in increased activity of SOD1 protein

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

serine palmitoyltransferase, long chain base subunit 2

increases expression

N-benzylpiperazine results in increased expression of SPTLC2 mRNA

NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542

G

squalene epoxidase

increases expression

N-benzylpiperazine results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sterol regulatory element binding transcription factor 1

increases expression

N-benzylpiperazine results in increased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

StAR-related lipid transfer domain containing 4

increases expression

N-benzylpiperazine results in increased expression of STARD4 mRNA

NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024

G

serine/threonine kinase 10

increases expression

N-benzylpiperazine results in increased expression of STK10 mRNA

NCBI chr10:17,117,860...17,212,065
Ensembl chr10:17,117,878...17,212,061

G

syntaxin 3

increases expression

N-benzylpiperazine results in increased expression of STX3 mRNA

NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805

G

tectonin beta-propeller repeat containing 1

increases expression

N-benzylpiperazine results in increased expression of TECPR1 mRNA

NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611

G

trefoil factor 1

increases expression

1-benzylpiperazine results in increased expression of TFF1 mRNA

NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597

G

transmembrane 4 L six family member 4

decreases expression

N-benzylpiperazine results in decreased expression of TM4SF4 mRNA

NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200

G

tripartite motif-containing 59

increases expression

N-benzylpiperazine results in increased expression of TRIM59 mRNA

NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031

G

tetratricopeptide repeat domain 36

decreases expression

N-benzylpiperazine results in decreased expression of TTC36 mRNA

NCBI chr 8:45,112,737...45,116,345

G

ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase

decreases expression

N-benzylpiperazine results in decreased expression of URAD mRNA

NCBI chr12:7,709,278...7,718,925
Ensembl chr12:7,709,312...7,718,923

G

ubiquitin specific peptidase 2

decreases expression

N-benzylpiperazine results in decreased expression of USP2 mRNA

NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331

G

WAP four-disulfide core domain 2

increases expression

N-benzylpiperazine results in increased expression of WFDC2 mRNA

NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807

2-methylserotonin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

5-hydroxytryptamine receptor 3A

multiple interactions

2-methyl-5-HT binds to and results in increased activity of HTR3A protein

NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389

G

interleukin 1 beta

multiple interactions

2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

2-methyl-5-HT promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

calcitonin-related polypeptide alpha

decreases expression

CGS 12066B results in decreased expression of CALCA mRNA

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

5-hydroxytryptamine receptor 1B

affects binding

CGS 12066B binds to HTR1B protein

NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549

4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

5-hydroxytryptamine receptor 1A

multiple interactions

[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to 1-(3-chlorophenyl)piperazine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Physostigmine]

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

5-methoxy-N,N-diisopropyltryptamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases activity
multiple interactions

5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein
[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions
decreases activity

[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily d, polypeptide 1

increases metabolic processing

CYP2D1 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine

NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084

G

cytochrome P450, family 2, subfamily d, polypeptide 2

increases metabolic processing

CYP2D2 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine

NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions
decreases activity

[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
decreases activity

[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

5-methoxytryptamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions

CYP2D6 protein binds to and results in decreased methylation of 5-Methoxytryptamine

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

5-hydroxytryptamine receptor 7

multiple interactions

[5-Methoxytryptamine binds to and results in increased activity of HTR7 protein] which results in increased abundance of Cyclic AMP

NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626

G

kynurenine 3-monooxygenase

increases expression

5-Methoxytryptamine results in increased expression of KMO mRNA

NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881

G

protein phosphatase 1, regulatory (inhibitor) subunit 1B

decreases phosphorylation
increases phosphorylation

5-Methoxytryptamine results in decreased phosphorylation of PPP1R1B protein
5-Methoxytryptamine results in increased phosphorylation of PPP1R1B protein

NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775

G

superoxide dismutase 2

decreases expression

5-Methoxytryptamine results in decreased expression of SOD2 mRNA

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

trace-amine-associated receptor 1

increases activity
multiple interactions

5-Methoxytryptamine results in increased activity of TAAR1 protein
[5-Methoxytryptamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP

NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084

G

tryptophan hydroxylase 1

decreases expression

5-Methoxytryptamine results in decreased expression of TPH1 mRNA

NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344

5-methyltryptamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions
decreases activity

[5-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions
decreases activity

[5-methyltryptamine analog results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases activity
multiple interactions

5-methyltryptamine analog results in decreased activity of CYP2C19 protein
[5-methyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions
decreases activity

[5-methyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity
multiple interactions

5-methyltryptamine analog results in decreased activity of CYP2E1 protein
[5-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

monoamine oxidase A

decreases activity

5-methyltryptamine results in decreased activity of MAOA protein

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

almotriptan

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases methylation
increases metabolic processing
increases hydroxylation

CYP1A1 protein results in decreased methylation of almotriptan
CYP1A1 protein results in increased metabolism of almotriptan
CYP1A1 protein results in increased hydroxylation of almotriptan

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases methylation

CYP1A2 protein results in decreased methylation of almotriptan

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases methylation

CYP2C19 protein results in decreased methylation of almotriptan

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily c, polypeptide 79

decreases methylation

CYP2C8 protein results in decreased methylation of almotriptan

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases methylation
increases hydroxylation

CYP2D6 protein results in decreased methylation of almotriptan
CYP2D6 protein results in increased hydroxylation of almotriptan

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases hydroxylation
decreases methylation

CYP3A4 protein results in increased hydroxylation of almotriptan
CYP3A4 protein results in decreased methylation of almotriptan

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

flavin containing dimethylaniline monoxygenase 3

increases oxidation

FMO3 protein results in increased oxidation of almotriptan

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

5-hydroxytryptamine receptor 1B

multiple interactions

HTR1B affects the reaction [almotriptan inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]]

NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549

G

monoamine oxidase A

increases metabolic processing

MAOA protein results in increased metabolism of almotriptan

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

alpha-methylserotonin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

interleukin 6

multiple interactions

alpha-methylserotonin results in increased expression of and results in increased secretion of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

aripiprazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acyl-CoA dehydrogenase, long chain

decreases expression

Aripiprazole results in decreased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

adenosine A2a receptor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ADORA2A mRNA

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

actin related protein 2/3 complex, subunit 1B

decreases expression

Aripiprazole results in decreased expression of ARPC1B mRNA

NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747

G

BCL10, immune signaling adaptor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of BCL10 mRNA

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

G

Bcl2-like 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of BCL2L1 mRNA

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

BCL6, transcription repressor

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

BH3 interacting domain death agonist

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of BID mRNA

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

complement C1r

multiple interactions

Aripiprazole promotes the reaction [Ozone results in decreased expression of C1R mRNA]

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

G

complement C2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of C2 mRNA

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

G

chromobox 7

decreases expression
increases expression

Aripiprazole results in decreased expression of CBX7 mRNA
Aripiprazole results in increased expression of CBX7 mRNA

NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973

G

C-C motif chemokine ligand 19

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL19 mRNA

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

G

C-C motif chemokine ligand 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 22

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in increased expression of CCL22 mRNA]

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

G

C-C motif chemokine ligand 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL3 mRNA

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL4 mRNA

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 5

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine receptor 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CCR3 mRNA

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

CD274 molecule

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CD274 mRNA

NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450

G

CD33 molecule

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CD33 mRNA

NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149

G

CD44 molecule

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

Cd70 molecule

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CD70 mRNA

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

G

CD83 molecule

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CD83 mRNA

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

G

cadherin 5

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in increased expression of CDH5 mRNA]

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cyclin-dependent kinase inhibitor 1A

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

CCAAT/enhancer binding protein beta

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

carboxylesterase 1D

multiple interactions

Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate]

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

complement factor B

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CFB mRNA

NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505

G

claudin 5

decreases expression

Aripiprazole results in decreased expression of CLDN5 mRNA

NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992

G

cannabinoid receptor 1

increases expression

Aripiprazole results in increased expression of CNR1 mRNA

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

catechol-O-methyltransferase

increases expression

Aripiprazole results in increased expression of COMT mRNA

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

cAMP responsive element binding protein 1

increases expression

Aripiprazole results in increased expression of CREB1 mRNA

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element binding protein 5

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CREB5 mRNA

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

CREB binding protein

decreases expression

Aripiprazole results in decreased expression of CREBBP mRNA

NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888

G

collapsin response mediator protein 1

increases expression

Aripiprazole results in increased expression of CRMP1 mRNA

NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177

G

colony stimulating factor 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CSF1 mRNA

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CSF2 mRNA

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CSF3 mRNA

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

C-X3-C motif chemokine ligand 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X-C motif chemokine ligand 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 5

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CXCR5 mRNA

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

G

C-X-C motif chemokine receptor 6

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CXCR6 mRNA

NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526

G

cytochrome b-245 beta chain

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

CYLD lysine 63 deubiquitinase

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of CYLD mRNA

NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658

G

discoidin domain receptor tyrosine kinase 2

decreases expression

Aripiprazole results in decreased expression of DDR2 mRNA

NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363

G

DExD-box helicase 50

increases expression

Aripiprazole results in increased expression of DDX50 mRNA

NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152

G

dynein, axonemal, light chain 4

decreases expression

Aripiprazole results in decreased expression of DNAL4 mRNA

NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283
Ensembl chr20:111,312,427...111,325,283

G

DNA methyltransferase 3 alpha

increases expression

Aripiprazole results in increased expression of DNMT3A mRNA

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

dopamine receptor D2

multiple interactions

[Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine

PMID:17069544 PMID:17327886

NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875

G

dual specificity phosphatase 4

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

dual specificity phosphatase 6

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

Epstein-Barr virus induced 3

multiple interactions

Aripiprazole promotes the reaction [Ozone results in increased expression of EBI3 mRNA]

NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544

G

early growth response 1

increases expression

Aripiprazole results in increased expression of EGR1 mRNA; Aripiprazole results in increased expression of EGR1 protein

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 2

increases expression

Aripiprazole results in increased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

early growth response 4

increases expression

Aripiprazole results in increased expression of EGR4 mRNA

NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328

G

elastase, neutrophil expressed

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ELANE mRNA

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

ELAV like RNA binding protein 2

increases expression

Aripiprazole results in increased expression of ELAVL2 mRNA

NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097

G

ETS proto-oncogene 1, transcription factor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ETS1 mRNA

NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010

G

exocyst complex component 2

increases expression

Aripiprazole results in increased expression of EXOC2 mRNA

NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289

G

F2R like trypsin receptor 1

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in increased expression of F2RL1 mRNA]

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

G

fasciculation and elongation protein zeta 1

multiple interactions
increases expression

[Aripiprazole co-treated with Ozone] results in increased expression of FEZ1 mRNA
Aripiprazole results in increased expression of FEZ1 mRNA

NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683

G

fibronectin 1

decreases expression

Aripiprazole results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

gamma-aminobutyric acid type A receptor subunit beta1

increases expression

Aripiprazole results in increased expression of GABRB1 mRNA

NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948

G

heparin-binding EGF-like growth factor

decreases expression

Aripiprazole results in decreased expression of HBEGF mRNA

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

5-hydroxytryptamine receptor 1A

multiple interactions

Aripiprazole binds to and affects the activity of HTR1A protein; Aripiprazole binds to and results in increased activity of HTR1A protein

PMID:17069544 PMID:21823597

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 2A

multiple interactions
decreases response to substance
affects response to substance

Aripiprazole binds to and results in decreased activity of HTR2A protein; Aripiprazole binds to and results in increased activity of HTR2A protein; Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein]
HTR2A gene SNP results in decreased susceptibility to Aripiprazole
HTR2A protein affects the susceptibility to Aripiprazole

PMID:16314884 PMID:21823597

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

5-hydroxytryptamine receptor 2C

multiple interactions

Aripiprazole binds to and affects the activity of HTR2C protein

NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287

G

intercellular adhesion molecule 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

intercellular adhesion molecule 4, Landsteiner-Wiener blood group

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ICAM4 mRNA

NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171

G

inducible T-cell co-stimulator ligand

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ICOSLG mRNA

NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703

G

interferon beta 1

increases expression
multiple interactions

Aripiprazole results in increased expression of IFNB1 mRNA
Aripiprazole promotes the reaction [Ozone results in increased expression of IFNB1 mRNA]

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of IFNG mRNA

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon gamma receptor 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IFNGR1 mRNA

NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IKBKE mRNA

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

G

interleukin 11

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL11 mRNA

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 1 alpha

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1A mRNA

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1R2 mRNA

NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725

G

interleukin 1 receptor accessory protein

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1RAP mRNA

NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530

G

interleukin 1 receptor accessory protein-like 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1RAPL2 mRNA

NCBI chr X:100,961,509...102,271,753
Ensembl chr X:100,961,812...102,271,753

G

interleukin 1 receptor-like 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL1RL1 mRNA

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 23 subunit alpha

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL23A mRNA

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 24

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL24 mRNA

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

interleukin 2 receptor subunit gamma

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of IL2RG mRNA

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

G

interleukin 4 receptor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL4R mRNA

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 5

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL5 mRNA

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL6 mRNA; Aripiprazole promotes the reaction [Ozone results in increased expression of IL6 mRNA]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7 receptor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of IL7R mRNA

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

inositol polyphosphate-5-phosphatase D

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of INPP5D mRNA

NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746

G

interleukin-1 receptor-associated kinase 2

multiple interactions

Aripiprazole promotes the reaction [Ozone results in increased expression of IRAK2 mRNA]

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

G

interferon regulatory factor 8

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of IRF8 mRNA

NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829

G

interferon stimulated exonuclease gene 20

increases expression
multiple interactions

Aripiprazole results in increased expression of ISG20 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of ISG20 mRNA

NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027

G

integrin subunit alpha 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ITGA2 mRNA

NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 5

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

potassium voltage-gated channel subfamily H member 2

multiple interactions
decreases activity

Aripiprazole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Aripiprazole results in decreased activity of KCNH2 protein

PMID:21158687 PMID:28551711

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

potassium inwardly-rectifying channel, subfamily J, member 3

increases expression

Aripiprazole results in increased expression of KCNJ3 mRNA

NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124

G

LIF, interleukin 6 family cytokine

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of LIF mRNA

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

G

leucine rich repeat neuronal 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of LRRN3 mRNA

NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330

G

lymphotoxin alpha

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of LTA mRNA

NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859

G

lymphotoxin beta

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

LYN proto-oncogene, Src family tyrosine kinase

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of LYN mRNA

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

G

monoamine oxidase B

increases expression

Aripiprazole results in increased expression of MAOB mRNA

NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003

G

mitogen-activated protein kinase 6

increases expression

Aripiprazole results in increased expression of MAPK6 mRNA

NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720

G

MAPK activated protein kinase 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of MAPKAPK2 mRNA

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

G

nuclear factor kappa B subunit 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of NFKB1 mRNA

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nuclear factor kappa B subunit 2

multiple interactions

Aripiprazole promotes the reaction [Ozone results in increased expression of NFKB2 mRNA]

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

NFKB inhibitor alpha

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of NFKBIA mRNA

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NLR family, pyrin domain containing 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of NLRP3 mRNA

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

nucleotide-binding oligomerization domain containing 2

multiple interactions
increases expression

[Aripiprazole co-treated with Ozone] results in increased expression of NOD2 mRNA
Aripiprazole results in increased expression of NOD2 mRNA

NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177

G

neural proliferation, differentiation and control, 1

decreases expression

Aripiprazole results in decreased expression of NPDC1 mRNA

NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866

G

5' nucleotidase, ecto

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881

G

neurotrimin

decreases expression

Aripiprazole results in decreased expression of NTM mRNA

NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595

G

programmed cell death 1 ligand 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PDCD1LG2 mRNA

NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938

G

platelet derived growth factor C

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of PDGFC mRNA

NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433

G

pyruvate dehydrogenase phosphatase catalytic subunit 1

increases expression

Aripiprazole results in increased expression of PDP1 mRNA

NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217

G

plasminogen activator, urokinase

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

plasminogen activator, urokinase receptor

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PLAUR mRNA

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

G

POU class 2 homeobox 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of POU2F2 mRNA

NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261

G

proteoglycan 2, pro eosinophil major basic protein

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PRG2 mRNA

NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101

G

protein kinase cAMP-activated catalytic subunit alpha

increases expression

Aripiprazole results in increased expression of PRKACA protein

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

G

protein kinase C, delta

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PRKCD mRNA

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

G

prolactin

multiple interactions
increases secretion
decreases secretion
decreases expression

Aripiprazole inhibits the reaction [haloperidol decanoate results in increased expression of PRL protein]; Aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein]
Aripiprazole results in increased secretion of PRL protein
Aripiprazole results in decreased secretion of PRL protein
Aripiprazole inhibits the reaction [talipexole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]
Aripiprazole results in decreased expression of PRL protein

PMID:8613910 PMID:17873694 PMID:19230981 PMID:19519261 PMID:19653986 More...

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

proline dehydrogenase

decreases expression

Aripiprazole results in decreased expression of PRODH mRNA

NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305

G

proteasome 26S subunit, ATPase 6

increases expression

Aripiprazole results in increased expression of PSMC6 mRNA

NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055

G

prostaglandin-endoperoxide synthase 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

PYD and CARD domain containing

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of PYCARD mRNA

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

G

RAB3A, member RAS oncogene family

increases expression

Aripiprazole results in increased expression of RAB3A mRNA

NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336

G

ras related dexamethasone induced 1

increases expression

Aripiprazole results in increased expression of RASD1 mRNA

NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186

G

RELB proto-oncogene, NF-kB subunit

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

RNA sensor RIG-1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of RIGI mRNA

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

G

SUMO1 activating enzyme subunit 1

increases expression

Aripiprazole results in increased expression of SAE1 mRNA

NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986

G

strawberry notch homolog 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of SBNO2 mRNA

NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527

G

serpin family B member 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of SERPINB2 mRNA

NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408

G

SH2B adaptor protein 2

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of SH2B2 mRNA

NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844

G

SLAM family member 6

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of SLAMF6 mRNA

NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300

G

solute carrier family 6 member 4

affects binding

Aripiprazole binds to SLC6A4 protein

NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384

G

solute carrier organic anion transporter family, member 2b1

decreases expression

Aripiprazole results in decreased expression of SLCO2B1 mRNA

NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353

G

slit guidance ligand 3

increases expression

Aripiprazole results in increased expression of SLIT3 mRNA

NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634

G

SMAD family member 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of SMAD3 mRNA

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

suppressor of cytokine signaling 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of SOCS1 mRNA

NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383

G

synaptotagmin 17

decreases expression
multiple interactions

Aripiprazole results in decreased expression of SYT17 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of SYT17 mRNA

NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960

G

TGF-beta activated kinase 1/MAP3K7 binding protein 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of TAB1 mRNA

NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058

G

tachykinin receptor 3

decreases expression
increases expression

Aripiprazole results in decreased expression of TACR3 mRNA
Aripiprazole results in increased expression of TACR3 mRNA

NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791

G

thrombomodulin

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of THBD mRNA

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

G

thrombospondin 1

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in increased expression of THBS1 mRNA]

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

TIR domain containing adaptor molecule 1

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TICAM1 mRNA

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

G

toll-like receptor 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of TLR3 mRNA

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

G

toll-like receptor 5

increases expression
multiple interactions

Aripiprazole results in increased expression of TLR5 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of TLR5 mRNA

NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738

G

tumor necrosis factor

multiple interactions

Aripiprazole promotes the reaction [Ozone results in increased expression of TNF mRNA]

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 3

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFAIP3 mRNA

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

G

TNF receptor superfamily member 11B

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in increased expression of TNFRSF11B mRNA]

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

G

TNF receptor superfamily member 12A

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF12A mRNA

NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045

G

TNF receptor superfamily member 14

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of TNFRSF14 mRNA

NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703

G

TNF receptor superfamily member 1B

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF1B mRNA

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

G

tumor necrosis factor receptor superfamily, member 22

multiple interactions

Aripiprazole inhibits the reaction [Ozone results in decreased expression of TNFRSF10C mRNA]

NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309

G

TNF receptor superfamily member 8

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF8 mRNA

NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421

G

TNF receptor superfamily member 9

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF9 mRNA

NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000

G

TNF superfamily member 10

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF10 mRNA

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 12

multiple interactions

[Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF12 mRNA

NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213

G

TNF superfamily member 15

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFSF15 mRNA

NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228

G

TNF superfamily member 18

multiple interactions

[Aripiprazole co-treated with Ozone] results in increased expression of TNFSF18 mRNA

NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169

G

tubulin, beta 2A class IIa

decreases expression

Aripiprazole results in decreased expression of TUBB2A mRNA

NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714

G

vascular endothelial growth factor A

multiple interactions

Aripiprazole promotes the reaction [Ozone results in increased expression of VEGFA mRNA]

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

WEE1 G2 checkpoint kinase

increases expression

Aripiprazole results in increased expression of WEE1 mRNA

NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688

G

zinc finger protein 354C

increases expression

Aripiprazole results in increased expression of ZNF354C mRNA

NCBI chr10:35,129,720...35,145,717
Ensembl chr10:35,132,959...35,145,661

buspirone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate-semialdehyde synthase

increases expression

Buspirone results in increased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP binding cassette subfamily A member 1

increases expression

Buspirone results in increased expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily C member 2

decreases expression

Buspirone results in decreased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily F member 1

decreases expression

Buspirone results in decreased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

ATP binding cassette subfamily G member 2

decreases expression

Buspirone results in decreased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

abhydrolase domain containing 14b

increases expression

Buspirone results in increased expression of ABHD14B mRNA

NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119

G

ankyrin repeat and BTB domain containing 1

increases expression

Buspirone results in increased expression of ABTB1 mRNA

NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:121,299,304...121,305,620

G

acetyl-CoA acyltransferase 2

increases expression

Buspirone results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acetyl-CoA carboxylase alpha

decreases expression

Buspirone results in decreased expression of ACACA mRNA

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA binding domain containing 4

increases expression

Buspirone results in increased expression of ACBD4 mRNA

NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500

G

ATP citrate lyase

decreases expression

Buspirone results in decreased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA synthetase family member 2

decreases expression

Buspirone results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 3

decreases expression

Buspirone results in decreased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase long-chain family member 4

increases expression

Buspirone results in increased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase long-chain family member 5

decreases expression

Buspirone results in decreased expression of ACSL5 mRNA

NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607

G

actin, beta

decreases expression

Buspirone results in decreased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin, gamma 1

decreases expression

Buspirone results in decreased expression of ACTG1 mRNA

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

G

actinin, alpha 1

decreases expression

Buspirone results in decreased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

aminoacylase 1

decreases expression

Buspirone results in decreased expression of ACY1 mRNA

NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682

G

ADAMTS-like 4

increases expression

Buspirone results in increased expression of ADAMTSL4 mRNA

NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848

G

adenylate cyclase 6

increases expression

Buspirone results in increased expression of ADCY6 mRNA

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

G

adiponectin receptor 2

decreases expression

Buspirone results in decreased expression of ADIPOR2 mRNA

NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355

G

adrenoceptor alpha 1A

multiple interactions

Buspirone binds to and results in decreased activity of ADRA1A protein

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

adrenoceptor alpha 1D

multiple interactions

Buspirone binds to and results in increased activity of ADRA1D protein

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

agmatinase

increases expression

Buspirone results in increased expression of AGMAT mRNA

NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276

G

adenosylhomocysteinase

increases expression

Buspirone results in increased expression of AHCY mRNA

NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393

G

allograft inflammatory factor 1

decreases expression

Buspirone results in decreased expression of AIF1 mRNA

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

androgen-induced 1

increases expression

Buspirone results in increased expression of AIG1 mRNA

NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084

G

adenylate kinase 4

decreases expression

Buspirone results in decreased expression of AK4 mRNA

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

A-kinase anchoring protein 8 like

increases expression

Buspirone results in increased expression of AKAP8L mRNA

NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275

G

aldo-keto reductase family 7 member A3

decreases expression

Buspirone results in decreased expression of AKR7A3 mRNA

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

aldehyde dehydrogenase 1 family, member B1

decreases expression

Buspirone results in decreased expression of ALDH1B1 mRNA

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

alkB homolog 7

increases expression

Buspirone results in increased expression of ALKBH7 mRNA

NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

Buspirone results in decreased expression of ANKH mRNA

NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187

G

ankyrin repeat and KH domain containing 1

increases expression

Buspirone results in increased expression of ANKHD1-EIF4EBP3 mRNA

NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024

G

ankyrin repeat domain 46

increases expression

Buspirone results in increased expression of ANKRD46 mRNA

NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132

G

ANTXR cell adhesion molecule 2

increases expression

Buspirone results in increased expression of ANTXR2 mRNA

NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094

G

annexin A3

decreases expression

Buspirone results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A5

decreases expression

Buspirone results in decreased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

apolipoprotein B

decreases expression

Buspirone results in decreased expression of APOB mRNA

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

Apol9a-Apol7a readthrough

decreases expression

Buspirone results in decreased expression of APOL7B mRNA

NCBI chr 7:109,118,559...109,149,798
Ensembl chr 7:109,131,064...109,147,649

G

apolipoprotein O

decreases expression

Buspirone results in decreased expression of APOO mRNA

NCBI chr X:59,157,971...59,262,940
Ensembl chr X:59,158,049...59,262,940

G

apolipoprotein O-like

decreases expression

Buspirone results in decreased expression of APOOL mRNA

NCBI chr X:77,377,723...77,443,672
Ensembl chr X:77,377,781...77,443,900

G

amyloid beta precursor protein

decreases expression

Buspirone results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

Rho GTPase activating protein 24

decreases expression

Buspirone results in decreased expression of ARHGAP24 mRNA

NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823

G

Rho GDP dissociation inhibitor beta

decreases expression

Buspirone results in decreased expression of ARHGDIB mRNA

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

ARF like GTPase 1

decreases expression

Buspirone results in decreased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

ARF like GTPase 4A

increases expression

Buspirone results in increased expression of ARL4A mRNA

NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066

G

ARL6 interacting reticulophagy regulator 1

decreases expression

Buspirone results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994

G

acidic residue methyltransferase 1

decreases expression

Buspirone results in decreased expression of ARMT1 mRNA

NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302

G

arylsulfatase B

decreases expression

Buspirone results in decreased expression of ARSB mRNA

NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671

G

arsenite methyltransferase

increases expression

Buspirone results in increased expression of AS3MT mRNA

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

decreases expression

Buspirone results in decreased expression of ASAP2 mRNA

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975

G

asialoglycoprotein receptor 1

increases expression

Buspirone results in increased expression of ASGR1 mRNA

NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631

G

asparaginase

increases expression

Buspirone results in increased expression of ASPG mRNA

NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268

G

activating transcription factor 5

increases expression

Buspirone results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

autophagy related 2B

increases expression

Buspirone results in increased expression of ATG2B mRNA

NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015

G

atlastin GTPase 2

increases expression

Buspirone results in increased expression of ATL2 mRNA

NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421

G

ATPase phospholipid transporting 11C

increases expression

Buspirone results in increased expression of ATP11C mRNA

NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204

G

ATPase H+ transporting V0 subunit B

increases expression

Buspirone results in increased expression of ATP6V0B mRNA

NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401

G

ATPase H+ transporting V0 subunit e1

increases expression

Buspirone results in increased expression of ATP6V0E1 mRNA

NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434

G

ATPase H+ transporting V1 subunit G1

increases expression

Buspirone results in increased expression of ATP6V1G1 mRNA

NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463

G

Axl receptor tyrosine kinase

decreases expression

Buspirone results in decreased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

antizyme inhibitor 1

decreases expression

Buspirone results in decreased expression of AZIN1 mRNA

NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

increases expression

Buspirone results in increased expression of B4GALNT1 mRNA

NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

Buspirone results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

biglycan

decreases expression

Buspirone results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e40

decreases expression

Buspirone results in decreased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

biliverdin reductase B

increases expression

Buspirone results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

BCL2 interacting protein 3

increases expression

Buspirone results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

bolA family member 1

increases expression

Buspirone results in increased expression of BOLA1 mRNA

NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576

G

bisphosphoglycerate mutase

decreases expression

Buspirone results in decreased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

BTG anti-proliferation factor 2

decreases expression

Buspirone results in decreased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

similar to human chromosome 17 open reading frame 58

increases expression

Buspirone results in increased expression of C10H17ORF58 mRNA

NCBI chr10:91,972,938...91,977,606
Ensembl chr10:91,972,410...91,977,602

G

complement C1q B chain

decreases expression

Buspirone results in decreased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

similar to human chromosome 1 open reading frame 50

increases expression

Buspirone results in increased expression of C5H1ORF50 mRNA

NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762

G

complement C5 like 1

increases expression

Buspirone results in increased expression of C5L1 mRNA

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

G

complement C6

decreases expression

Buspirone results in decreased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

complement C8 gamma chain

increases expression

Buspirone results in increased expression of C8G mRNA

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

G

similar to human chromosome 11 open reading frame 54

decreases expression

Buspirone results in decreased expression of C8H11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 11 open reading frame 65

increases expression

Buspirone results in increased expression of C8H11ORF65 mRNA

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

similar to human chromosome 11 open reading frame 71

increases expression

Buspirone results in increased expression of C8H11ORF71 mRNA

NCBI chr 8:48,838,556...48,838,970
Ensembl chr 8:48,838,100...48,842,270

G

similar to human chromosome 15 open reading frame 61

increases expression

Buspirone results in increased expression of C8H15ORF61 mRNA

NCBI chr 8:63,868,125...63,872,863
Ensembl chr 8:63,868,125...63,872,751

G

caldesmon 1

decreases expression

Buspirone results in decreased expression of CALD1 mRNA

NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932

G

calmodulin 1

decreases expression

Buspirone results in decreased expression of CALM1 mRNA

NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227

G

calmodulin 2

decreases expression

Buspirone results in decreased expression of CALM2 mRNA

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

calreticulin

decreases expression

Buspirone results in decreased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

cyclase associated actin cytoskeleton regulatory protein 1

decreases expression

Buspirone results in decreased expression of CAP1 mRNA

NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769

G

carbonic anhydrase 3

decreases expression

Buspirone results in decreased expression of CAR3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 5A

increases expression

Buspirone results in increased expression of CAR5A mRNA

NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906

G

caspase 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased cleavage of CASP1 protein]

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 3

decreases expression

Buspirone results in decreased expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 6

increases expression

Buspirone results in increased expression of CASP6 mRNA

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

decreases expression

Buspirone results in decreased expression of CASP7 mRNA

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

catalase

increases expression

Buspirone results in increased expression of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 4

increases expression

Buspirone results in increased expression of CBR4 mRNA

NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712

G

coiled-coil domain containing 6

increases expression

Buspirone results in increased expression of CCDC6 mRNA

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

G

coiled-coil domain containing 80

decreases expression

Buspirone results in decreased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 9

decreases expression

Buspirone results in decreased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cyclin B2

decreases expression

Buspirone results in decreased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

decreases expression

Buspirone results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

CD164 molecule

decreases expression

Buspirone results in decreased expression of CD164 mRNA

NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634

G

Cd5 molecule-like

decreases expression

Buspirone results in decreased expression of CD5L mRNA

NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753

G

Cd68 molecule

decreases expression

Buspirone results in decreased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CD74 molecule

decreases expression

Buspirone results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cell division cycle 20

decreases expression

Buspirone results in decreased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

cyclin-dependent kinase 1

decreases expression

Buspirone results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase inhibitor 2C

decreases expression

Buspirone results in decreased expression of CDKN2C mRNA

NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278

G

cyclin-dependent kinase inhibitor 3

decreases expression

Buspirone results in decreased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CEA cell adhesion molecule 1

decreases expression

Buspirone results in decreased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CEA cell adhesion molecule 4

decreases expression

Buspirone results in decreased expression of CEACAM10 mRNA

NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915

G

centrosomal protein 20

decreases expression

Buspirone results in decreased expression of CEP20 mRNA

NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837

G

cofilin 1

decreases expression

Buspirone results in decreased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

cingulin

decreases expression

Buspirone results in decreased expression of CGN mRNA

NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645

G

choline phosphotransferase 1

increases expression

Buspirone results in increased expression of CHPT1 mRNA

NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103

G

churchill domain containing 1

increases expression

Buspirone results in increased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

CDC28 protein kinase regulatory subunit 2

decreases expression

Buspirone results in decreased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

C-type lectin domain family 4, member F

decreases expression

Buspirone results in decreased expression of CLEC4F mRNA

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

chloride intracellular channel 1

decreases expression

Buspirone results in decreased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

ClpB family mitochondrial disaggregase

decreases expression

Buspirone results in decreased expression of CLPB mRNA

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

G

clathrin, light chain B

increases expression

Buspirone results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

Buspirone results in decreased expression of CMTM6 mRNA

NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033

G

cyclin Pas1/PHO80 domain containing 1

increases expression

Buspirone results in increased expression of CNPPD1 mRNA

NCBI chr 9:76,633,475...76,640,164
Ensembl chr 9:76,633,477...76,640,188

G

cannabinoid receptor 1

affects response to substance

CNR1 affects the susceptibility to Buspirone

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

cordon-bleu WH2 repeat protein-like 1

increases expression

Buspirone results in increased expression of COBLL1 mRNA

NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194

G

collagen type XIV alpha 1 chain

decreases expression

Buspirone results in decreased expression of COL14A1 mRNA

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

collagen type I alpha 2 chain

decreases expression

Buspirone results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

decreases expression

Buspirone results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

COMM domain containing 5

increases expression

Buspirone results in increased expression of COMMD5 mRNA

NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764

G

COPI coat complex subunit gamma 1

decreases expression

Buspirone results in decreased expression of COPG1 mRNA

NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616

G

coronin 1C

decreases expression

Buspirone results in decreased expression of CORO1C mRNA

NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179

G

cytochrome c oxidase assembly factor COX14

increases expression

Buspirone results in increased expression of COX14 mRNA

NCBI chr 7:130,852,226...130,854,316

G

cytochrome c oxidase subunit 7A2 like

increases expression

Buspirone results in increased expression of COX7A2L mRNA

NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273

G

carnitine palmitoyltransferase 1A

increases expression

Buspirone results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

increases expression

Buspirone results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

cAMP responsive element modulator

decreases expression

Buspirone results in decreased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

cryptochrome circadian regulator 1

decreases expression

Buspirone results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

chromosome segregation 1 like

decreases expression

Buspirone results in decreased expression of CSE1L mRNA

NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865

G

colony stimulating factor 1 receptor

decreases expression

Buspirone results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

casein kinase 2 alpha 2

increases expression

Buspirone results in increased expression of CSNK2A2 mRNA

NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080

G

cysteine and glycine-rich protein 1

decreases expression

Buspirone results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cathepsin D

increases expression

Buspirone results in increased expression of CTSD mRNA

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin L

increases expression

Buspirone results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cathepsin S

decreases expression

Buspirone results in decreased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

cathepsin Z

decreases expression

Buspirone results in decreased expression of CTSZ mRNA

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

C-X-C motif chemokine ligand 11

increases expression

Buspirone results in increased expression of CXCL11 mRNA

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

cytochrome b-245 beta chain

decreases expression

Buspirone results in decreased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

Buspirone results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily c, polypeptide 22

decreases expression

Buspirone results in decreased expression of CYP2C22 mRNA

NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738

G

cytochrome P450, family 2, subfamily d, polypeptide 4

increases oxidation
increases expression

CYP2D6 protein results in increased oxidation of Buspirone
Buspirone results in increased expression of CYP2D4 mRNA

PMID:15640381 PMID:24136188

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily j, polypeptide 3

increases expression

Buspirone results in increased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases oxidation
increases metabolic processing
multiple interactions

CYP3A4 protein results in increased oxidation of Buspirone
CYP3A4 protein results in increased metabolism of Buspirone
Resveratrol inhibits the reaction [CYP3A4 protein results in increased metabolism of Buspirone]

PMID:15640381 PMID:20716633

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases oxidation
increases expression

CYP3A5 protein results in increased oxidation of Buspirone
Buspirone results in increased expression of CYP3A9 mRNA

PMID:15640381 PMID:24136188

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

Buspirone results in increased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily b, polypeptide 1

increases expression

Buspirone results in increased expression of CYP4B1 mRNA

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

Buspirone results in decreased expression of CYP4F1 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

G

cytochrome P450, family 4, subfamily f, polypeptide 4

increases expression

Buspirone results in increased expression of CYP4F4 mRNA

NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506

G

cytochrome P450 family 8 subfamily B member 1

increases expression

Buspirone results in increased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dishevelled associated activator of morphogenesis 1

decreases expression

Buspirone results in decreased expression of DAAM1 mRNA

NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114

G

DAB adaptor protein 2

decreases expression

Buspirone results in decreased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

death associated protein kinase 1

decreases expression

Buspirone results in decreased expression of DAPK1 mRNA

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

diazepam binding inhibitor

decreases expression

Buspirone results in decreased expression of DBI mRNA

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

G

dopa decarboxylase

decreases expression

Buspirone results in decreased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DDHD domain containing 1

decreases expression

Buspirone results in decreased expression of DDHD1 mRNA

NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952

G

DEAD-box helicase 1

decreases expression

Buspirone results in decreased expression of DDX1 mRNA

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

G

2,4-dienoyl-CoA reductase 1

increases expression

Buspirone results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

DEK proto-oncogene

decreases expression

Buspirone results in decreased expression of DEK mRNA

NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808

G

DEP domain containing MTOR-interacting protein

increases expression

Buspirone results in increased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

dehydrogenase/reductase 7

increases expression

Buspirone results in increased expression of DHRS7 mRNA

NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892

G

dihydrolipoamide dehydrogenase

decreases expression

Buspirone results in decreased expression of DLD mRNA

NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

Buspirone results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member C9

decreases expression

Buspirone results in decreased expression of DNAJC9 mRNA

NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118

G

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

increases expression

Buspirone results in increased expression of DPM1 mRNA

NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

increases expression

Buspirone results in increased expression of DPM3 mRNA

NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668

G

dihydropyrimidinase-like 2

decreases expression

Buspirone results in decreased expression of DPYSL2 mRNA

NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829

G

deoxythymidylate kinase

decreases expression

Buspirone results in decreased expression of DTYMK mRNA

NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870

G

deoxyuridine triphosphatase

decreases expression

Buspirone results in decreased expression of DUT mRNA

NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771

G

dynein light chain LC8-type 1

decreases expression

Buspirone results in decreased expression of DYNLL1 mRNA

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

G

dynein light chain Tctex-type 3

decreases expression

Buspirone results in decreased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

enoyl-CoA hydratase 1

increases expression

Buspirone results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

ethylmalonyl-CoA decarboxylase 1

decreases expression

Buspirone results in decreased expression of ECHDC1 mRNA

NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319

G

enoyl CoA hydratase domain containing 3

increases expression

Buspirone results in increased expression of ECHDC3 mRNA

NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516

G

enoyl-CoA delta isomerase 1

increases expression

Buspirone results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

ER degradation enhancing alpha-mannosidase like protein 1

increases expression

Buspirone results in increased expression of EDEM1 mRNA

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

G

elongation factor Tu GTP binding domain containing 2

decreases expression

Buspirone results in decreased expression of EFTUD2 mRNA

NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079

G

EH domain binding protein 1

decreases expression

Buspirone results in decreased expression of EHBP1 mRNA

NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332

G

EI24, autophagy associated transmembrane protein

increases expression

Buspirone results in increased expression of EI24 mRNA

NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571

G

eukaryotic translation initiation factor 3, subunit C

decreases expression

Buspirone results in decreased expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 3, subunit L

decreases expression

Buspirone results in decreased expression of EIF3L mRNA

NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614

G

eukaryotic translation initiation factor 4A2

increases expression

Buspirone results in increased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

eukaryotic translation initiation factor 4B

increases expression

Buspirone results in increased expression of EIF4B mRNA

NCBI chr 7:133,206,637...133,228,436

G

ELOVL fatty acid elongase 5

decreases expression

Buspirone results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

ELOVL fatty acid elongase 6

decreases expression

Buspirone results in decreased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

glutamyl aminopeptidase

decreases expression

Buspirone results in decreased expression of ENPEP mRNA

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

epoxide hydrolase 1

decreases expression

Buspirone results in decreased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

ergosterol biosynthesis 28 homolog

increases expression

Buspirone results in increased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

endoplasmic reticulum-golgi intermediate compartment 1

decreases expression

Buspirone results in decreased expression of ERGIC1 mRNA

NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957

G

endoplasmic reticulum protein 29

decreases expression

Buspirone results in decreased expression of ERP29 mRNA

NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376

G

ethanolamine kinase 2

increases expression

Buspirone results in increased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

EWS RNA-binding protein 1

decreases expression

Buspirone results in decreased expression of EWSR1 mRNA

NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544

G

exosome component 5

increases expression

Buspirone results in increased expression of EXOSC5 mRNA

NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265

G

fatty acid binding protein 5

decreases expression

Buspirone results in decreased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid desaturase 1

decreases expression

Buspirone results in decreased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

decreases expression

Buspirone results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

FAM111 trypsin like peptidase A

decreases expression

Buspirone results in decreased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

family with sequence similarity 98, member A

decreases expression

Buspirone results in decreased expression of FAM98A mRNA

NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742

G

fatty acid synthase

decreases expression

Buspirone results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 1

decreases expression

Buspirone results in decreased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

F-box protein 31

increases expression

Buspirone results in increased expression of FBXO31 mRNA

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

F-box and WD repeat domain containing 2

increases expression

Buspirone results in increased expression of FBXW2 mRNA

NCBI chr 3:18,088,859...18,114,387
Ensembl chr 3:18,088,865...18,114,381

G

Fc gamma receptor 2A

decreases expression

Buspirone results in decreased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

fasciculation and elongation protein zeta 2

decreases expression

Buspirone results in decreased expression of FEZ2 mRNA

NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626

G

fibrinogen alpha chain

decreases expression

Buspirone results in decreased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibroblast growth factor receptor 2

decreases expression

Buspirone results in decreased expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

folliculin

increases expression

Buspirone results in increased expression of FLCN mRNA

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

G

flavin containing dimethylaniline monoxygenase 3

increases expression

Buspirone results in increased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

flavin containing dimethylaniline monoxygenase 5

increases expression

Buspirone results in increased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

forkhead box A3

increases expression

Buspirone results in increased expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box O1

increases expression

Buspirone results in increased expression of FOXO1 mRNA

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

follistatin-like 1

decreases expression

Buspirone results in decreased expression of FSTL1 mRNA

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

formimidoyltransferase cyclodeaminase

increases expression

Buspirone results in increased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

Fus RNA binding protein

decreases expression

Buspirone results in decreased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FXYD domain-containing ion transport regulator 1

increases expression

Buspirone results in increased expression of FXYD1 mRNA

NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278

G

G0/G1switch 2

increases expression

Buspirone results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

decreases expression

Buspirone results in decreased expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

Buspirone results in decreased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase 1

decreases expression

Buspirone results in decreased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

glycyl-tRNA synthetase 1

decreases expression

Buspirone results in decreased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest specific 5

increases expression

Buspirone results in increased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

1,4-alpha-glucan branching enzyme 1

decreases expression

Buspirone results in decreased expression of GBE1 mRNA

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

glutaryl-CoA dehydrogenase

increases expression

Buspirone results in increased expression of GCDH mRNA

NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681

G

GTP cyclohydrolase I feedback regulator

increases expression

Buspirone results in increased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

Buspirone results in decreased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glycerophosphodiester phosphodiesterase 1

increases expression

Buspirone results in increased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

GDP dissociation inhibitor 2

decreases expression

Buspirone results in decreased expression of GDI2 mRNA

NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366

G

G elongation factor, mitochondrial 1

decreases expression

Buspirone results in decreased expression of GFM1 mRNA

NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471

G

gamma-glutamyl carboxylase

decreases expression

Buspirone results in decreased expression of GGCX mRNA

NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063

G

growth hormone receptor

decreases expression

Buspirone results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

glycine decarboxylase

decreases expression

Buspirone results in decreased expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

glutaredoxin

increases expression

Buspirone results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glycine-N-acyltransferase

increases expression

Buspirone results in increased expression of GLYAT mRNA

NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942

G

glucosamine-phosphate N-acetyltransferase 1

decreases expression

Buspirone results in decreased expression of GNPNAT1 mRNA

NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739

G

glycerol-3-phosphate acyltransferase, mitochondrial

decreases expression

Buspirone results in decreased expression of GPAM mRNA

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

glycerol-3-phosphate dehydrogenase 1

decreases expression

Buspirone results in decreased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

glutamic--pyruvic transaminase

increases expression

Buspirone results in increased expression of GPT mRNA

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

G1 to S phase transition 1

decreases expression

Buspirone results in decreased expression of GSPT1 mRNA

NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198

G

glutathione S-transferase pi 1

increases expression

Buspirone results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

increases expression

Buspirone results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

H1.0 linker histone

decreases expression

Buspirone results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.Z variant histone 1

decreases expression

Buspirone results in decreased expression of H2AZ1 mRNA

NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485

G

3-hydroxyacyl-CoA dehydratase 2

decreases expression

Buspirone results in decreased expression of HACD2 mRNA

NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889

G

3-hydroxyacyl-CoA dehydratase 3

decreases expression

Buspirone results in decreased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

2-hydroxyacyl-CoA lyase 1

increases expression

Buspirone results in increased expression of HACL1 mRNA

NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

Buspirone results in increased expression of HADHB mRNA

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacid oxidase 1

decreases expression

Buspirone results in decreased expression of HAO1 mRNA

NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721

G

histone acetyltransferase 1

decreases expression

Buspirone results in decreased expression of HAT1 mRNA

NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517

G

HAUS augmin-like complex, subunit 4

decreases expression

Buspirone results in decreased expression of HAUS4 mRNA

NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938

G

hemoglobin alpha, adult chain 1

decreases expression

Buspirone results in decreased expression of HBA-A1 mRNA

NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin alpha, adult chain 2

decreases expression

Buspirone results in decreased expression of HBA1 mRNA

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
Ensembl chr10:15,307,815...15,338,392

G

HECT domain E3 ubiquitin protein ligase 1

increases expression

Buspirone results in increased expression of HECTD1 mRNA

NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

Buspirone results in increased expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 1

increases expression

Buspirone results in increased expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes family bHLH transcription factor 6

decreases expression

Buspirone results in decreased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hexosaminidase subunit beta

increases expression

Buspirone results in increased expression of HEXB mRNA

NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223

G

hematopoietically expressed homeobox

decreases expression

Buspirone results in decreased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

Buspirone results in increased expression of HIBCH mRNA

NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824

G

HIG1 hypoxia inducible domain family, member 2A

increases expression

Buspirone results in increased expression of HIGD2A mRNA

NCBI chr17:10,021,853...10,022,777
Ensembl chr17:10,021,859...10,022,796

G

high mobility group box 2

decreases expression

Buspirone results in decreased expression of HMGB2 mRNA

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140

G

high mobility group nucleosomal binding domain 2

decreases expression

Buspirone results in decreased expression of HMGN2 mRNA

NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
Ensembl chr16:146,192,126...146,195,521

G

high mobility group nucleosomal binding domain 3

decreases expression

Buspirone results in decreased expression of HMGN3 mRNA

NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976

G

heme oxygenase 1

multiple interactions
increases expression

Buspirone inhibits the reaction [Methotrexate results in decreased expression of HMOX1 mRNA]
Buspirone results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A1

decreases expression

Buspirone results in decreased expression of HNRNPA1 mRNA

NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609

G

heterogeneous nuclear ribonucleoprotein A2/B1

decreases expression

Buspirone results in decreased expression of HNRNPA2B1 mRNA

NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249

G

heterogeneous nuclear ribonucleoprotein M

decreases expression

Buspirone results in decreased expression of HNRNPM mRNA

NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762

G

heterogeneous nuclear ribonucleoprotein R

decreases expression

Buspirone results in decreased expression of HNRNPR mRNA

NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867

G

hypoxanthine phosphoribosyltransferase 1

increases expression

Buspirone results in increased expression of HPRT1 mRNA

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

hydroxysteroid dehydrogenase like 2

increases expression

Buspirone results in increased expression of HSDL2 mRNA

NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839

G

heat shock protein family A (Hsp70) member 13

decreases expression

Buspirone results in decreased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 5

decreases expression

Buspirone results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

HIV-1 Tat specific factor 1

decreases expression

Buspirone results in decreased expression of HTATSF1 mRNA

NCBI chr X:134,935,426...134,949,607
Ensembl chr X:134,935,426...134,949,607

G

5-hydroxytryptamine receptor 1A

multiple interactions

Buspirone binds to and affects the activity of HTR1A protein
Buspirone binds to and results in decreased activity of HTR1A protein

PMID:2207497 PMID:15482641

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 2A

decreases expression

Buspirone results in decreased expression of HTR2A protein

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

hyaluronidase 3

decreases expression

Buspirone results in decreased expression of HYAL3 mRNA

NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647

G

hyccin PI4KA lipid kinase complex subunit 2

increases expression

Buspirone results in increased expression of HYCC2 mRNA

NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007

G

isoleucyl-tRNA synthetase 1

decreases expression

Buspirone results in decreased expression of IARS1 mRNA

NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237

G

intercellular adhesion molecule 1

decreases expression

Buspirone results in decreased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interferon-induced protein with tetratricopeptide repeats 2

decreases expression

Buspirone results in decreased expression of IFIT2 mRNA

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

G

interferon induced transmembrane protein 1

decreases expression

Buspirone results in decreased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

insulin-like growth factor 1

decreases expression

Buspirone results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 7

decreases expression

Buspirone results in decreased expression of IGFBP7 mRNA

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

IK cytokine

decreases expression

Buspirone results in decreased expression of IK mRNA

NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832

G

interleukin 1 beta

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 6 receptor

increases expression

Buspirone results in increased expression of IL6R mRNA

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

G

IMP U3 small nucleolar ribonucleoprotein 3

increases expression

Buspirone results in increased expression of IMP3 mRNA

NCBI chr 8:57,339,528...57,340,416
Ensembl chr 8:57,339,496...57,340,414

G

inhibin subunit beta A

decreases expression

Buspirone results in decreased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inositol hexakisphosphate kinase 1

increases expression

Buspirone results in increased expression of IP6K1 mRNA

NCBI chr 8:108,693,068...108,737,278

G

importin 9

decreases expression

Buspirone results in decreased expression of IPO9 mRNA

NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673

G

interferon regulatory factor 1

decreases expression

Buspirone results in decreased expression of IRF1 mRNA

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 7

decreases expression

Buspirone results in decreased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

immunity-related GTPase M

decreases expression

Buspirone results in decreased expression of IRGM mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

integrin subunit alpha 6

decreases expression

Buspirone results in decreased expression of ITGA6 mRNA

NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428

G

integrin subunit beta 2

decreases expression

Buspirone results in decreased expression of ITGB2 mRNA

NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600

G

Janus kinase 1

decreases expression

Buspirone results in decreased expression of JAK1 mRNA

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

junctional adhesion molecule 2

decreases expression

Buspirone results in decreased expression of JAM2 mRNA

NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063

G

Jupiter microtubule associated homolog 2

decreases expression

Buspirone results in decreased expression of JPT2 mRNA

NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression

Buspirone results in decreased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

junction plakoglobin

decreases expression

Buspirone results in decreased expression of JUP mRNA

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

potassium channel tetramerization domain containing 5

increases expression

Buspirone results in increased expression of KCTD5 mRNA

NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209

G

Kelch-like ECH-associated protein 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of KEAP1 mRNA]

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KH RNA binding domain containing, signal transduction associated 1

decreases expression

Buspirone results in decreased expression of KHDRBS1 mRNA

NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180

G

KLF transcription factor 15

increases expression

Buspirone results in increased expression of KLF15 mRNA

NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374

G

KLF transcription factor 9

increases expression

Buspirone results in increased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kelch-like family member 24

increases expression

Buspirone results in increased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

karyopherin subunit alpha 2

decreases expression

Buspirone results in decreased expression of KPNA2 mRNA

NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150

G

karyopherin subunit beta 1

decreases expression

Buspirone results in decreased expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

keratin 18

decreases expression

Buspirone results in decreased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166

G

kynurenine aminotransferase 1

increases expression

Buspirone results in increased expression of KYAT1 mRNA

NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355

G

kynurenine aminotransferase 3

increases expression

Buspirone results in increased expression of KYAT3 mRNA

NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227

G

lactamase, beta

decreases expression

Buspirone results in decreased expression of LACTB mRNA

NCBI chr 8:67,571,504...67,587,592
Ensembl chr 8:67,571,500...67,587,539

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

increases expression

Buspirone results in increased expression of LAMTOR2 mRNA

NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013

G

lipopolysaccharide binding protein

increases expression

Buspirone results in increased expression of LBP mRNA

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

G

leucine carboxyl methyltransferase 1

decreases expression

Buspirone results in decreased expression of LCMT1 mRNA

NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112

G

lymphocyte cytosolic protein 1

decreases expression

Buspirone results in decreased expression of LCP1 mRNA

NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680

G

leptin receptor overlapping transcript-like 1

increases expression

Buspirone results in increased expression of LEPROTL1 mRNA

NCBI chr16:58,040,934...58,053,602
Ensembl chr16:58,040,960...58,053,593

G

leucine zipper and EF-hand containing transmembrane protein 1

decreases expression

Buspirone results in decreased expression of LETM1 mRNA

NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904

G

galectin 3

decreases expression

Buspirone results in decreased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

galectin 5

decreases expression

Buspirone results in decreased expression of LGALS5 mRNA

NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153

G

galectin 9

decreases expression

Buspirone results in decreased expression of LGALS9 mRNA

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

G

galectin-like

decreases expression

Buspirone results in decreased expression of LGALSL mRNA

NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980

G

legumain

decreases expression

Buspirone results in decreased expression of LGMN mRNA

NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480

G

lipase C, hepatic type

decreases expression

Buspirone results in decreased expression of LIPC mRNA

NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464

G

lectin, mannose-binding, 1

decreases expression

Buspirone results in decreased expression of LMAN1 mRNA

NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851

G

lecithin retinol acyltransferase

decreases expression

Buspirone results in decreased expression of LRAT mRNA

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

LDL receptor related protein 11

increases expression

Buspirone results in increased expression of LRP11 mRNA

NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110

G

leucine rich repeat containing 59

decreases expression

Buspirone results in decreased expression of LRRC59 mRNA

NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533

G

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

decreases expression

Buspirone results in decreased expression of LSM6 mRNA

NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484

G

leukotriene A4 hydrolase

decreases expression

Buspirone results in decreased expression of LTA4H mRNA

NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600

G

lymphocyte antigen 6 family member E

decreases expression

Buspirone results in decreased expression of LY6E mRNA

NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689

G

lymphatic vessel endothelial hyaluronan receptor 1

decreases expression

Buspirone results in decreased expression of LYVE1 mRNA

NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309

G

lysozyme 2

decreases expression

Buspirone results in decreased expression of LYZ2 mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

microtubule-associated protein 1 light chain 3 beta

increases expression

Buspirone results in increased expression of MAP1LC3B mRNA

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690

G

mitogen-activated protein kinase 9

decreases expression

Buspirone results in decreased expression of MAPK9 mRNA

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

microtubule-associated protein, RP/EB family, member 1

decreases expression

Buspirone results in decreased expression of MAPRE1 mRNA

NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983

G

membrane associated ring-CH-type finger 2

increases expression

Buspirone results in increased expression of MARCHF2 mRNA

NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794

G

membrane associated ring-CH-type finger 6

increases expression

Buspirone results in increased expression of MARCHF6 mRNA

NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910

G

MARCKS-like 1

decreases expression

Buspirone results in decreased expression of MARCKSL1 mRNA

NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817

G

meiosis regulator and mRNA stability factor 1

increases expression

Buspirone results in increased expression of MARF1 mRNA

NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753

G

methionine adenosyltransferase 1A

increases expression

Buspirone results in increased expression of MAT1A mRNA

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

mannose binding lectin 2

decreases expression

Buspirone results in decreased expression of MBL2 mRNA

NCBI chr 1:228,016,439...228,024,736

G

minichromosome maintenance complex component 7

decreases expression

Buspirone results in decreased expression of MCM7 mRNA

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

malic enzyme 1

decreases expression

Buspirone results in decreased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

methyltransferase 23, arginine

increases expression

Buspirone results in increased expression of METTL23 mRNA

NCBI chr10:102,047,090...102,053,379
Ensembl chr10:102,047,314...102,051,977

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

Buspirone results in increased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

monoglyceride lipase

decreases expression

Buspirone results in decreased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

MID1 interacting protein 1

decreases expression

Buspirone results in decreased expression of MID1IP1 mRNA

NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774

G

macrophage migration inhibitory factor

decreases expression

Buspirone results in decreased expression of MIF mRNA

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504

G

mortality factor 4 like 2

decreases expression

Buspirone results in decreased expression of MORF4L2 mRNA

NCBI chr X:100,082,562...100,093,658
Ensembl chr X:100,082,404...100,093,728

G

mitochondrial ribosomal protein L1

decreases expression

Buspirone results in decreased expression of MRPL1 mRNA

NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721

G

mitochondrial ribosomal protein L15

decreases expression

Buspirone results in decreased expression of MRPL15 mRNA

NCBI chr 5:14,729,961...14,741,276
Ensembl chr 5:14,729,979...14,741,276

G

mitochondrial ribosomal protein L34

increases expression

Buspirone results in increased expression of MRPL34 mRNA

NCBI chr16:18,152,470...18,153,205
Ensembl chr16:18,151,342...18,153,208

G

mitochondrial ribosomal protein S22

decreases expression

Buspirone results in decreased expression of MRPS22 mRNA

NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291

G

metallothionein 1

increases expression

Buspirone results in increased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr X:10,826,032...10,827,049

G

mitochondrial amidoxime reducing component 2

increases expression

Buspirone results in increased expression of MTARC2 mRNA

NCBI chr13:96,362,810...96,397,284

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

decreases expression

Buspirone results in decreased expression of MTHFD1 mRNA

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

MTSS I-BAR domain containing 1

increases expression

Buspirone results in increased expression of MTSS1 mRNA

NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968

G

microsomal triglyceride transfer protein

decreases expression

Buspirone results in decreased expression of MTTP mRNA

NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239

G

murinoglobulin 1

decreases expression

Buspirone results in decreased expression of MUG1 mRNA

NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051

G

MYD88, innate immune signal transduction adaptor

increases expression

Buspirone results in increased expression of MYD88 mRNA

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

myosin, heavy chain 9

decreases expression

Buspirone results in decreased expression of MYH9 mRNA

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

decreases expression

Buspirone results in decreased expression of NAA15 mRNA

NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756

G

N-acetylneuraminate synthase

decreases expression

Buspirone results in decreased expression of NANS mRNA

NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950

G

Nedd4 family interacting protein 1

increases expression

Buspirone results in increased expression of NDFIP1 mRNA

NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311

G

NADH:ubiquinone oxidoreductase subunit A6

increases expression

Buspirone results in increased expression of NDUFA6 mRNA

NCBI chr 7:113,866,382...113,870,239
Ensembl chr 7:113,866,382...113,870,239

G

NADH:ubiquinone oxidoreductase subunit A7

increases expression

Buspirone results in increased expression of NDUFA7 mRNA

NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976

G

NADH:ubiquinone oxidoreductase subunit B2

increases expression

Buspirone results in increased expression of NDUFB2 mRNA

NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851

G

nectin cell adhesion molecule 3

decreases expression

Buspirone results in decreased expression of NECTIN3 mRNA

NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
increases expression

Buspirone results in decreased expression of NFE2L2 mRNA
Buspirone inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 mRNA]
Buspirone results in increased expression of NFE2L2 mRNA

PMID:24136188 PMID:37341015

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NHP2 ribonucleoprotein

decreases expression

Buspirone results in decreased expression of NHP2 mRNA

NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545

G

nidogen 1

decreases expression

Buspirone results in decreased expression of NID1 mRNA

NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267

G

nitrilase 1

increases expression

Buspirone results in increased expression of NIT1 mRNA

NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332

G

neurolysin

decreases expression

Buspirone results in decreased expression of NLN mRNA

NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914

G

NLR family, pyrin domain containing 3

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of NLRP3 protein]

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression

Buspirone results in decreased expression of NME1 mRNA

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

NME/NM23 nucleoside diphosphate kinase 3

increases expression

Buspirone results in increased expression of NME3 mRNA

NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359

G

NOP53 ribosome biogenesis factor

increases expression

Buspirone results in increased expression of NOP53 mRNA

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

G

NOP58 ribonucleoprotein

decreases expression

Buspirone results in decreased expression of NOL5 mRNA

NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810

G

nitric oxide synthase 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of NOS1 mRNA]

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

G

notch receptor 2

decreases expression

Buspirone results in decreased expression of NOTCH2 mRNA

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

nuclear receptor subfamily 1, group D, member 2

increases expression

Buspirone results in increased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 1, group I, member 2

increases expression

Buspirone results in increased expression of NR1I2 mRNA

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor binding protein 2

increases expression

Buspirone results in increased expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

neuronal regeneration related protein

decreases expression

Buspirone results in decreased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL

decreases expression

Buspirone results in decreased expression of NSDHL mRNA

NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142

G

5' nucleotidase, ecto

decreases expression

Buspirone results in decreased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881