|
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| G
|
Angpt1
|
angiopoietin 1
|
increases expression
|
EXP ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of ANGPT1 mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of ANGPT1 protein
|
CTD |
PMID:16735674 |
|
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
|
|
| G
|
Bach1
|
BTB domain and CNC homolog 1
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [alpha-pyrrolidinononanophenone analog results in increased expression of BACH1 protein]
|
CTD |
PMID:38040126 |
|
NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277
|
|
| G
|
Bmp4
|
bone morphogenetic protein 4
|
increases expression
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of BMP4 mRNA
|
CTD |
PMID:15991191 |
|
NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
|
|
| G
|
Cav1
|
caveolin 1
|
multiple interactions increases expression
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased ubiquitination of and results in decreased degradation of CAV1 protein; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased metabolism of and results in increased stability of CAV1 protein 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CAV1 protein
|
CTD |
PMID:19706615 |
|
NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
|
|
| G
|
Ccn4
|
cellular communication network factor 4
|
multiple interactions increases expression
|
ISO
|
CREB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; CTNNB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; Cycloheximide inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]; Dactinomycin inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA] 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 protein
|
CTD |
PMID:19238344 |
|
NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094
|
|
| G
|
Cdh2
|
cadherin 2
|
increases expression multiple interactions affects response to substance
|
ISO EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CDH2 mRNA CDH2 protein affects the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA] CDH2 protein affects the susceptibility to 2,2'-(hydroxynitrosohydrazono)bis-ethanamine
|
CTD |
PMID:16580782 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cldn5
|
claudin 5
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 protein]
|
CTD |
PMID:34391839 |
|
NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
increases phosphorylation multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased phosphorylation of CREB1 protein CREB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]
|
CTD |
PMID:19238344 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
increases expression increases activity multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased activity of CTNNB1 protein CDH2 protein affects the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA]; CTNNB1 mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA]
|
CTD |
PMID:16580782 PMID:19238344 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
decreases activity
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A1 protein
|
CTD |
PMID:15542068 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
decreases activity
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A2 protein
|
CTD |
PMID:15542068 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Gfap
|
glial fibrillary acidic protein
|
decreases expression
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased expression of GFAP mRNA
|
CTD |
PMID:16580782 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine affects the reaction [alpha-pyrrolidinononanophenone analog affects the expression of HMOX1 protein]
|
CTD |
PMID:38040126 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hnrnpd
|
heterogeneous nuclear ribonucleoprotein D
|
multiple interactions increases expression
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [HNRNPD protein binds to MMP9 3' UTR]; HNRNPD mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]] 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of HNRNPD protein
|
CTD |
PMID:16683234 |
|
NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Fructose results in increased expression of ICAM1 protein]
|
CTD |
PMID:18508964 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]
|
CTD |
PMID:16378139 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine promotes the reaction [HNRNPD protein binds to MMP9 3' UTR]; HNRNPD mutant form inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP9 protein]]
|
CTD |
PMID:16378139 PMID:16683234 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Ncf1
|
neutrophil cytosolic factor 1
|
increases metabolic processing
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased metabolism of NCF1 protein
|
CTD |
PMID:17568572 |
|
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
|
|
| G
|
Neurog1
|
neurogenin 1
|
increases expression
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of NEUROG1 mRNA
|
CTD |
PMID:16580782 |
|
NCBI chr17:8,368,096...8,369,615
Ensembl chr17:8,368,096...8,369,615
|
|
| G
|
Ocln
|
occludin
|
increases expression
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of OCLN protein
|
CTD |
PMID:16735674 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
| G
|
Rasd1
|
ras related dexamethasone induced 1
|
multiple interactions
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased nitrosation of and results in increased activity of RASD1 protein
|
CTD |
PMID:16908409 |
|
NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710
|
|
| G
|
Slc26a4
|
solute carrier family 26 member 4
|
decreases expression
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased expression of SLC26A4 protein
|
CTD |
PMID:22811483 |
|
NCBI chr 6:53,835,102...53,873,968
Ensembl chr 6:53,835,110...53,873,216
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
multiple interactions increases response to substance
|
EXP ISO
|
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein]; 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA]; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [Doxorubicin results in increased expression of SOD2 protein]; [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein; [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA; Dactinomycin inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA] SOD2 protein results in increased susceptibility to 2,2'-(hydroxynitrosohydrazono)bis-ethanamine
|
CTD |
PMID:10511315 PMID:14996425 PMID:19286953 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Tek
|
TEK receptor tyrosine kinase
|
increases expression
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TEK mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TEK protein
|
CTD |
PMID:16735674 |
|
NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
increases expression
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TGFB1 mRNA; 2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of TGFB1 protein
|
CTD |
PMID:12798441 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [TNF protein results in increased secretion of VWF protein]
|
CTD |
PMID:34678311 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Vamp2
|
vesicle-associated membrane protein 2
|
multiple interactions
|
EXP
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [lead acetate affects the localization of VAMP2 protein]
|
CTD |
PMID:22265330 |
|
NCBI chr10:54,292,423...54,296,657
Ensembl chr10:54,292,806...54,296,654
|
|
| G
|
Vwf
|
von Willebrand factor
|
multiple interactions
|
ISO
|
2,2'-(hydroxynitrosohydrazono)bis-ethanamine inhibits the reaction [TNF protein results in increased secretion of VWF protein]
|
CTD |
PMID:34678311 |
|
NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757
|
|
|
|
| G
|
Abcb1b
|
ATP-binding cassette, sub-family B member 1B
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ABCB1B mRNA
|
CTD |
PMID:14600272 PMID:23052194 |
|
NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
affects abundance
|
EXP
|
ABCC2 protein affects the abundance of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone metabolite
|
CTD |
PMID:17724374 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Aco1
|
aconitase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ACO1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of ACSL1 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Agpat1
|
1-acylglycerol-3-phosphate O-acyltransferase 1
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of AGPAT1 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr20:4,140,565...4,149,531
Ensembl chr20:4,140,565...4,150,445
|
|
| G
|
Aif1
|
allograft inflammatory factor 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of AIF1 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
increases metabolic processing
|
ISO
|
AKR1C1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:11306090 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akr1c2
|
aldo-keto reductase family 1, member C2
|
increases metabolic processing
|
ISO
|
AKR1C2 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:11306090 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686
|
|
| G
|
Akr7a3
|
aldo-keto reductase family 7 member A3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of AKR7A3 mRNA
|
CTD |
PMID:14600272 PMID:23052194 |
|
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions increases phosphorylation
|
ISO
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of EIF4EBP1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3A protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of AKT1 protein]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]; methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein]
|
CTD |
PMID:12511591 PMID:34784199 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ALDH1A1 mRNA
|
CTD |
PMID:14600272 PMID:22484513 PMID:23052194 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Aldh7a1
|
aldehyde dehydrogenase 7 family, member A1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ALDH7A1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467
|
|
| G
|
Anxa2
|
annexin A2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ANXA2 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
|
|
| G
|
Apex1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of APEX1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329
|
|
| G
|
Aph1b
|
aph-1 homolog B, gamma secretase subunit
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of APH1B mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:76,310,380...76,331,428
|
|
| G
|
Arid4b
|
AT-rich interaction domain 4B
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of ARID4B mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr17:55,833,908...55,958,382
Ensembl chr17:55,833,908...55,958,382
|
|
| G
|
Asl
|
argininosuccinate lyase
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ASL mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261
|
|
| G
|
Atf1
|
activating transcription factor 1
|
increases phosphorylation multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]
|
CTD |
PMID:16671086 |
|
NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485
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| G
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Atf3
|
activating transcription factor 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ATF3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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|
| G
|
Atm
|
ATM serine/threonine kinase
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of ATM mRNA]
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CTD |
PMID:21882252 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
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| G
|
Atp5mc1
|
ATP synthase membrane subunit c locus 1
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of ATP5MC1 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363
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|
| G
|
Atp6v1d
|
ATPase H+ transporting V1 subunit D
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ATP6V1D mRNA
|
CTD |
PMID:14600272 PMID:22484513 PMID:23052194 |
|
NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346
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|
| G
|
B4galt1
|
beta-1,4-galactosyltransferase 1
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of B4GALT1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of B4GALT1 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445
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|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAD protein]
|
CTD |
PMID:18508827 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
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|
| G
|
Barhl1
|
BarH-like homeobox 1
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BARHL1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BARHL1 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 3:32,639,283...32,646,605
Ensembl chr 3:32,638,644...32,646,605
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| G
|
Bax
|
BCL2 associated X, apoptosis regulator
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multiple interactions decreases expression increases expression
|
ISO EXP
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BAX mRNA; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of BAX protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BAX mRNA] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BAX protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BAX mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:21882252 PMID:22484513 PMID:23052194 PMID:30259641 More...
|
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions increases expression
|
ISO
|
Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 mRNA]; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BCL2 protein
|
CTD |
PMID:16582591 PMID:16835749 PMID:18508827 PMID:21776270 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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|
| G
|
Bhmt
|
betaine-homocysteine S-methyltransferase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BHMT mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715
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|
| G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
increases expression increases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein NNK increases expression of BIRC3 protein in nonsmall cell lung cancer cells SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BIRC3 protein]
|
CTD RGD |
PMID:18508827 PMID:18508827 |
RGD:152998973 |
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
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|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of BIRC5 mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of and results in increased expression of BIRC5 protein
|
CTD |
PMID:21167638 PMID:21776270 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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|
| G
|
Bola3
|
bolA family member 3
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BOLA3 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of BOLA3 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 4:117,411,044...117,420,491
Ensembl chr 4:117,410,680...117,420,491
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|
| G
|
Brca1
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BRCA1, DNA repair associated
|
increases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BRCA1 mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of BRCA1 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BTG2 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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|
| G
|
Btg3
|
BTG anti-proliferation factor 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of BTG3 mRNA
|
CTD |
PMID:22484513 PMID:23052194 |
|
NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082
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|
| G
|
Casp8
|
caspase 8
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CASP8 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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|
| G
|
Cbr1
|
carbonyl reductase 1
|
increases metabolic processing multiple interactions
|
ISO
|
CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone Ethacrynic Acid inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Quercetin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Rutin inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Vitamin K 3 inhibits the reaction [CBR1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
|
CTD |
PMID:11306090 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCL2 protein
|
CTD |
PMID:15762874 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccnb1
|
cyclin B1
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCNB1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions increases expression
|
ISO EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK4 protein binds to CCND1 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK6 protein binds to CCND1 protein]; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; Benzamides analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; diphenyleneiodonium inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 protein
|
CTD |
PMID:14600272 PMID:15890375 PMID:18805435 PMID:22484513 PMID:28321046 PMID:30236600 More...
|
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
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|
| G
|
Ccne1
|
cyclin E1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCNE1 protein
|
CTD |
PMID:30236600 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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|
| G
|
Ccng1
|
cyclin G1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCNG1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
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|
| G
|
Cct3
|
chaperonin containing TCP1 subunit 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCT3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925
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|
| G
|
Cdc20
|
cell division cycle 20
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDC20 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
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|
| G
|
Cdh1
|
cadherin 1
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDH1 protein
|
CTD |
PMID:30236600 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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|
| G
|
Cdh2
|
cadherin 2
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDH2 protein
|
CTD |
PMID:30236600 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDK1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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|
| G
|
Cdk16
|
cyclin-dependent kinase 16
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK16 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr X:4,046,330...4,057,825
Ensembl chr X:4,026,866...4,057,380
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|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
multiple interactions increases expression
|
ISO EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK4 protein binds to CCND1 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK4 mRNA
|
CTD |
PMID:15890375 PMID:18805435 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk6
|
cyclin-dependent kinase 6
|
multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK6 protein binds to CCND1 protein]
|
CTD |
PMID:18805435 |
|
NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
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|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression decreases expression multiple interactions
|
ISO EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A protein 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CDKN1A protein; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CDKN1A protein]
|
CTD |
PMID:14600272 PMID:15890375 PMID:18508827 PMID:18805435 PMID:20421341 PMID:21167638 PMID:22484513 PMID:23052194 PMID:30236600 More...
|
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1B protein 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1B protein]
|
CTD |
PMID:18805435 PMID:30236600 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
|
|
| G
|
Cdkn2a
|
cyclin-dependent kinase inhibitor 2A
|
multiple interactions
|
ISO
|
[Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A mRNA; [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of CDKN2A protein
|
CTD |
PMID:21167638 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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|
| G
|
Ces2c
|
carboxylesterase 2C
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CES2C mRNA
|
CTD |
PMID:23052194 |
|
NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:270,374,913...270,384,801
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|
| G
|
Ces2h
|
carboxylesterase 2H
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CES2 mRNA
|
CTD |
PMID:14600272 PMID:22484513 |
|
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
|
|
| G
|
Cgref1
|
cell growth regulator with EF hand domain 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CGREF1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 |
|
NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800
|
|
| G
|
Cgrrf1
|
cell growth regulator with ring finger domain 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CGRRF1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811
|
|
| G
|
Chd1l
|
chromodomain helicase DNA binding protein 1-like
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CHD1L mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 2:187,819,869...187,906,359
Ensembl chr 2:187,811,954...187,890,477
|
|
| G
|
Chrna7
|
cholinergic receptor nicotinic alpha 7 subunit
|
increases expression increases activity affects binding
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CHRNA7 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CHRNA7 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone binds to CHRNA7 protein
|
CTD |
PMID:16835749 PMID:17459420 PMID:19027725 |
|
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
|
|
| G
|
Chrna9
|
cholinergic receptor nicotinic alpha 9 subunit
|
multiple interactions
|
ISO
|
[Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CHRNA9 protein
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CTD |
PMID:30259641 |
|
NCBI chr14:42,588,948...42,595,669
Ensembl chr14:42,588,948...42,595,669
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| G
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Cntn1
|
contactin 1
|
increases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CNTN1 mRNA]
|
CTD |
PMID:19027725 |
|
NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391
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| G
|
Col6a1
|
collagen type VI alpha 1 chain
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of COL6A1 protein
|
CTD |
PMID:23692979 |
|
NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
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|
| G
|
Commd1
|
copper metabolism domain containing 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of COMMD1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr14:101,081,667...101,185,738
Ensembl chr14:101,081,667...101,185,639
|
|
| G
|
Cox17
|
cytochrome c oxidase copper chaperone COX17
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of COX17 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of COX17 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019
|
|
| G
|
Cr1l
|
complement C3b/C4b receptor 1 like
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CR1L mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
increases phosphorylation multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]
|
CTD |
PMID:16671086 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
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|
| G
|
Cryab
|
crystallin, alpha B
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CRYAB mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Cstb
|
cystatin B
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CSTB mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199
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|
| G
|
Ctnnb1
|
catenin beta 1
|
multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein]; wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTNNB1 protein]
|
CTD |
PMID:28321046 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Ctsd
|
cathepsin D
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSD mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
|
|
| G
|
Ctss
|
cathepsin S
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTSS mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CXCL10 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
|
|
| G
|
Cyb5a
|
cytochrome b5 type A
|
multiple interactions
|
ISO
|
CYB5A protein promotes the reaction [CYP2A6 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
|
CTD |
PMID:15728263 |
|
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094 Ensembl chr18:14,453,966...14,455,094
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|
| G
|
Cyb5r3
|
cytochrome b5 reductase 3
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CYB5R3 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO EXP
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CYP1A1 mRNA; CYP1A1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1A1 mRNA]; Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:11774366 PMID:20146248 PMID:23052194 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
|
|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions increases activity
|
ISO
|
CYP1A2 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP1A2 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:11774366 PMID:15728263 |
|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
|
|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions
|
ISO
|
CYP1B1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA]
|
CTD |
PMID:11774366 PMID:20146248 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
|
|
| G
|
Cyp2a1
|
cytochrome P450, family 2, subfamily a, polypeptide 1
|
multiple interactions increases hydroxylation decreases metabolic processing increases activity increases metabolic processing decreases hydroxylation affects metabolic processing
|
ISO
|
[CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-hydroxy-1-(3-pyridyl)-1-butanone; [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-oxo-4-(3-pyridinebutanal); [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] which results in increased abundance of 4-oxo-4-(3-pyridyl)butanoic acid; CYP2A13 gene polymorphism inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; CYP2A13 protein promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; CYP2A13 protein results in increased metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; CYP2A13 protein results in increased metabolism of and results in increased susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; Methoxsalen inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Methoxsalen inhibits the reaction [CYP2A13 protein results in increased metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Metyrapone inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Miconazole inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Tranylcypromine inhibits the reaction [CYP2A13 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CYP2A13 protein results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; CYP2A13 results in increased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2A13 protein SNP results in decreased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2A13 results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2A13 gene polymorphism results in decreased hydroxylation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2A13 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:12920169 PMID:14633739 PMID:15608128 PMID:16917071 PMID:17671098 PMID:17717079 PMID:17922361 PMID:18669584 PMID:21473878 PMID:26231820 PMID:27567546 More...
|
|
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
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|
| G
|
Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
increases activity
|
EXP
|
CYP2B1 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:10799646 |
|
NCBI chr 1:90,646,098...90,669,762
|
|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
affects metabolic processing multiple interactions increases activity
|
ISO
|
CYP2B6 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone [CYP2B6 protein co-treated with cupric chloride co-treated with NADP] results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2B6 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:10799646 PMID:12920169 PMID:32672941 |
|
NCBI chr 1:90,780,468...90,859,852
|
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| G
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Cyp2c12
|
cytochrome P450, family 2, subfamily c, polypeptide 12
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP2C12 mRNA
|
CTD |
PMID:22484513 PMID:23052194 |
|
NCBI chr 1:248,619,887...248,681,945
Ensembl chr 1:248,619,882...248,677,042
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|
| G
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Cyp2c6
|
cytochrome P450, family 2, subfamily C, polypeptide 6
|
multiple interactions
|
ISO
|
CYP2C19 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:11774366 |
|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
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|
| G
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Cyp2d4
|
cytochrome P450, family 2, subfamily d, polypeptide 4
|
increases metabolic processing
|
ISO
|
CYP2D6 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:2070484 |
|
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
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|
| G
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Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
affects metabolic processing increases metabolic processing increases activity
|
ISO EXP
|
CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein
|
CTD |
PMID:9774145 PMID:12115524 PMID:12920169 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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|
| G
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Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions increases metabolic processing
|
ISO
|
CYP3A4 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CYP3A4 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:9029045 PMID:11774366 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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|
| G
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Dapk1
|
death associated protein kinase 1
|
increases methylation
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased methylation of DAPK1 promoter
|
CTD |
PMID:15172992 |
|
NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
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|
| G
|
Dcn
|
decorin
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DCN mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
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|
| G
|
Ddah1
|
dimethylarginine dimethylaminohydrolase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DDAH1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626
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|
| G
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Ddx21
|
DExD-box helicase 21
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DDX21 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
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|
| G
|
Dhrs3
|
dehydrogenase/reductase 3
|
increases metabolic processing
|
ISO
|
DHRS3 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:25451588 |
|
NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653
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|
| G
|
Dhrs7
|
dehydrogenase/reductase 7
|
increases reduction
|
ISO
|
DHRS7 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:24246760 |
|
NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744
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|
| G
|
Dkc1
|
dyskerin pseudouridine synthase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKC1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr X:157,751,651...157,757,796
Ensembl chr Y:380,743...385,405 Ensembl chr X:380,743...385,405
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|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
multiple interactions increases expression
|
ISO
|
Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; Benzamides analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; diphenyleneiodonium inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]; Wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]
|
CTD |
PMID:28321046 |
|
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
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|
| G
|
Dmbt1
|
deleted in malignant brain tumors 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DMBT1 mRNA
|
CTD |
PMID:23052194 |
|
NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:195,047,713...195,126,704
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|
| G
|
Dpyd
|
dihydropyrimidine dehydrogenase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of DPYD mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
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|
| G
|
Dusp6
|
dual specificity phosphatase 6
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of DUSP6 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
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|
| G
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Dut
|
deoxyuridine triphosphatase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DUT mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956
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|
| G
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Eef1g
|
eukaryotic translation elongation factor 1 gamma
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EEF1G mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
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|
| G
|
Eef2
|
eukaryotic translation elongation factor 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EEF2 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
increases phosphorylation multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:16671086 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
increases expression multiple interactions
|
EXP ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EIF4EBP1 mRNA [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of EIF4EBP1 protein
|
CTD |
PMID:12511591 PMID:15890375 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
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|
| G
|
Ephx1
|
epoxide hydrolase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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|
| G
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Fam162a
|
family with sequence similarity 162, member A
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FAM162A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560
|
|
| G
|
Fasn
|
fatty acid synthase
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FASN protein
|
CTD |
PMID:18413838 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fen1
|
flap structure-specific endonuclease 1
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein]
|
CTD |
PMID:35435490 |
|
NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016
|
|
| G
|
Fkbp4
|
FKBP prolyl isomerase 4
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FKBP4 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918
|
|
| G
|
Fn1
|
fibronectin 1
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FN1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FOS mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of FOS mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Foxp1
|
forkhead box P1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of FOXP1 mRNA alternative form
|
CTD |
PMID:35435490 |
|
NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272
|
|
| G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FTH1 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
|
|
| G
|
Fxyd3
|
FXYD domain-containing ion transport regulator 3
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of FXYD3 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr 1:95,432,918...95,440,129
Ensembl chr 1:95,432,919...95,439,702
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GADD45A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gas6
|
growth arrest specific 6
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GAS6 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088
|
|
| G
|
Gata3
|
GATA binding protein 3
|
multiple interactions increases expression increases activity
|
ISO
|
Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GATA3 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GATA3 mRNA
|
CTD |
PMID:16582591 PMID:16835749 |
|
NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GCLC mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gdf15
|
growth differentiation factor 15
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GDF15 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:23052194 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gls2
|
glutaminase 2
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GLS2 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013
|
|
| G
|
Gnmt
|
glycine N-methyltransferase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GNMT mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692
|
|
| G
|
Gria3
|
glutamate ionotropic receptor AMPA type subunit 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GRIA3 mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679
|
|
| G
|
Grpel1
|
GrpE-like 1, mitochondrial
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GRPEL1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr14:78,517,049...78,522,868
Ensembl chr14:78,517,052...78,522,861
|
|
| G
|
Gsk3a
|
glycogen synthase kinase 3 alpha
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3A protein
|
CTD |
PMID:12511591 |
|
NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:89,943,669...89,953,593
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein
|
CTD |
PMID:12511591 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSR mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gss
|
glutathione synthetase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSS mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
|
|
| G
|
Gsta2
|
glutathione S-transferase alpha 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA2 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092
|
|
| G
|
Gsta4
|
glutathione S-transferase alpha 4
|
decreases expression increases expression increases activity
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GSTA4 mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA4 mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of GSTA4 protein
|
CTD |
PMID:9774145 |
|
NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
|
|
| G
|
Gsta5
|
glutathione S-transferase alpha 5
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GSTA5 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765
|
|
| G
|
Gtpbp1
|
GTP binding protein 1
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of GTPBP1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 7:113,128,645...113,153,094
Ensembl chr 7:113,128,670...113,154,621
|
|
| G
|
H2ax
|
H2A.X variant histone
|
multiple interactions increases expression increases phosphorylation
|
ISO EXP
|
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of H2AX protein; Caffeine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of H2AX protein]; CYP2A13 protein promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of H2AX protein]; GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; methyllycaconitine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form]; Wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX mRNA
|
CTD |
PMID:15890375 PMID:21882252 PMID:26231820 PMID:34784199 PMID:35435490 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
H2az1
|
H2A.Z variant histone 1
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of H2AZ1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:229,026,464...229,031,411
Ensembl chr 2:229,028,843...229,031,411
|
|
| G
|
H3f4
|
H3.4 histone, cluster member
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H3-4 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr10:44,240,282...44,240,842
|
|
| G
|
Hba-a3
|
hemoglobin alpha, adult chain 3
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HBA2 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr10:15,816,099...15,816,943
Ensembl chr10:15,816,096...15,817,167
|
|
| G
|
Hcrtr2
|
hypocretin receptor 2
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HCRTR2 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 8:85,870,279...85,986,405
Ensembl chr 8:85,870,279...85,986,405
|
|
| G
|
Hdc
|
histidine decarboxylase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HDC mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
|
|
| G
|
Hes1
|
hes family bHLH transcription factor 1
|
multiple interactions increases expression
|
ISO
|
2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HES1 mRNA]
|
CTD |
PMID:28321046 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
| G
|
Hmgb2
|
high mobility group box 2
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of HMGB2 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions increases expression
|
ISO EXP
|
SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein]; zinc protoporphyrin analog inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HMOX1 mRNA
|
CTD |
PMID:15890375 PMID:18508827 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
multiple interactions increases mutagenesis
|
ISO
|
[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene; Dibutyl Phthalate promotes the reaction [[Ozone co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of HPRT1 gene] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of HPRT1 gene
|
CTD |
PMID:15613823 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Hsd11b1
|
hydroxysteroid 11-beta dehydrogenase 1
|
multiple interactions increases reduction
|
ISO
|
drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Ethinyl Estradiol inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Progesterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]; Testosterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone]
|
CTD |
PMID:28257955 |
|
NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
|
|
| G
|
Hsd11b2
|
hydroxysteroid 11-beta dehydrogenase 2
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA; Grape Seed Proanthocyanidins inhibits the reaction [[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of HSD11B2 mRNA]
|
CTD |
PMID:20146248 |
|
NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812
|
|
| G
|
Hsf1
|
heat shock transcription factor 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSF1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
|
|
| G
|
Hspa9
|
heat shock protein family A (Hsp70) member 9
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPA9 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398
|
|
| G
|
Hspb1
|
heat shock protein family B (small) member 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPB1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
|
|
| G
|
Hspe1
|
heat shock protein family E (Hsp10) member 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPE1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502
|
|
| G
|
Hsph1
|
heat shock protein family H (Hsp110) member 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPH1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891
|
|
| G
|
Ide
|
insulin degrading enzyme
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IDE mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:244,415,495...244,516,925
Ensembl chr 1:244,416,343...244,514,526
|
|
| G
|
Igfbp1
|
insulin-like growth factor binding protein 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IGFBP1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
|
|
| G
|
Igfbp2
|
insulin-like growth factor binding protein 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IGFBP2 mRNA
|
CTD |
PMID:22484513 PMID:23052194 |
|
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of IGFBP3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Il6
|
interleukin 6
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of IL6 protein
|
CTD |
PMID:15762874 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Inmt
|
indolethylamine N-methyltransferase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of INMT mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755
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| G
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Ints4
|
integrator complex subunit 4
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of INTS4 mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 1:161,201,284...161,265,042
Ensembl chr 1:161,197,708...161,269,124
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| G
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Irf1
|
interferon regulatory factor 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of IRF1 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
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|
| G
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Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of JUN mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of JUN mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
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Kras
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KRAS proto-oncogene, GTPase
|
increases mutagenesis multiple interactions
|
EXP ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased mutagenesis of KRAS gene [Lipopolysaccharides co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased mutagenesis of KRAS gene
|
CTD |
PMID:18271921 PMID:21868532 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
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|
| G
|
Krt15
|
keratin 15
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of KRT15 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142
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|
| G
|
Lama5
|
laminin subunit alpha 5
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of LAMA5 mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173
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|
| G
|
Lgals3
|
galectin 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of LGALS3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
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|
| G
|
Ltb4r
|
leukotriene B4 receptor
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of LTB4R mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr15:33,233,120...33,235,636
Ensembl chr15:33,232,820...33,235,637
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|
| G
|
Map2k1
|
mitogen activated protein kinase kinase 1
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K1 protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K1 protein]
|
CTD |
PMID:21882252 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
|
|
| G
|
Map2k2
|
mitogen activated protein kinase kinase 2
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAP2K2 protein]
|
CTD |
PMID:21882252 |
|
NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases phosphorylation increases activity multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MAPK1 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of MAPK1 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK1 protein; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of MAPK1 protein; Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:15603589 PMID:16671086 PMID:17459420 PMID:18508827 PMID:21882252 PMID:30236600 PMID:30259641 More...
|
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases activity multiple interactions increases phosphorylation
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MAPK3 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of and results in increased activity of MAPK3 protein; [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK3 protein; [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of MAPK3 protein; Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:15603589 PMID:16671086 PMID:17459420 PMID:18508827 PMID:21882252 PMID:30236600 PMID:30259641 More...
|
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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|
| G
|
Mat1a
|
methionine adenosyltransferase 1A
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MAT1A mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr16:17,017,168...17,035,368
Ensembl chr16:17,016,030...17,035,367
|
|
| G
|
Mcam
|
melanoma cell adhesion molecule
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MCAM mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406
|
|
| G
|
Mcm6
|
minichromosome maintenance complex component 6
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MCM6 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MGMT mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:22484513 PMID:23052194 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
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|
| G
|
Mir155
|
microRNA 155
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIR155 mRNA
|
CTD |
PMID:32326378 |
|
NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178
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|
| G
|
Mir21
|
microRNA 21
|
multiple interactions increases expression
|
ISO
|
MIR21 mRNA affects the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIR21 mRNA
|
CTD |
PMID:32326378 |
|
NCBI chr10:71,902,600...71,902,691
|
|
| G
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Mis18a
|
MIS18 kinetochore protein A
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MIS18A mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr11:43,454,129...43,467,157
Ensembl chr11:43,454,161...43,476,264
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|
| G
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Mki67
|
marker of proliferation Ki-67
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MKI67 protein
|
CTD |
PMID:21776270 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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|
| G
|
Mlh1
|
mutL homolog 1
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MLH1 mRNA
|
CTD |
PMID:32326378 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
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|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MMP9 mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of MMP9 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
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Mrpl41
|
mitochondrial ribosomal protein L41
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MRPL41 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MRPL41 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 3:28,178,837...28,179,755
Ensembl chr 3:28,162,197...28,181,250
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|
| G
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Msh2
|
mutS homolog 2
|
multiple interactions decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of and affects the localization of MSH2 protein; MIR21 mRNA affects the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MSH2 mRNA
|
CTD |
PMID:32326378 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
|
|
| G
|
Mt1-ps3
|
metallothionein 1, pseudogene 3
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MT1E mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of MT1E mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr17:79,695,812...79,696,200
Ensembl chr17:79,695,809...79,696,200
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|
| G
|
Mt1a
|
metallothionein 1A
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT1A mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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|
| G
|
Mt2
|
metallothionein 2
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT2A mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
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|
| G
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Mta2
|
metastasis associated 1 family, member 2
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MTA2 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 1:215,267,286...215,276,008
Ensembl chr 1:215,267,046...215,276,062
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|
| G
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Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases activity increases expression
|
ISO EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of MYC protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MYC mRNA
|
CTD |
PMID:15890375 PMID:17459420 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
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|
| G
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Nanog
|
Nanog homeobox
|
increases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NANOG protein [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of NANOG protein
|
CTD |
PMID:30259641 |
|
NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061
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|
| G
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Nap1l1
|
nucleosome assembly protein 1-like 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NAP1L1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104
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|
| G
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Nfkb1
|
nuclear factor kappa B subunit 1
|
increases activity multiple interactions increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NFKB1 mRNA]; SN50 peptide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of NFKB1 protein]
|
CTD |
PMID:16582591 PMID:16835749 PMID:18508827 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
increases phosphorylation
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of NFKBIA protein
|
CTD |
PMID:18508827 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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|
| G
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Nhej1
|
nonhomologous end-joining factor 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NHEJ1 mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 9:83,974,995...84,071,161
Ensembl chr 9:83,974,997...84,070,594
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|
| G
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Nipbl
|
NIPBL, cohesin loading factor
|
multiple interactions increases expression increases response to substance
|
ISO
|
NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of FEN1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein modified form] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NIPBL mRNA alternative form NIPBL mRNA alternative form results in increased susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:35435490 |
|
NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277
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|
| G
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Npc1
|
NPC intracellular cholesterol transporter 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NPC1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800
|
|
| G
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Npm1
|
nucleophosmin 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NPM1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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|
| G
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Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NQO1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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|
| G
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Nrcam
|
neuronal cell adhesion molecule
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NRCAM mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 6:67,129,723...67,425,510
Ensembl chr 6:67,129,801...67,430,539
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|
| G
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Nrg1
|
neuregulin 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of NRG1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:23052194 |
|
NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849
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|
| G
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Nubpl
|
NUBP iron-sulfur cluster assembly factor, mitochondrial
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUBPL mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 6:75,294,609...75,516,603
Ensembl chr 6:75,294,632...75,516,601
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|
| G
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Nupr1
|
nuclear protein 1, transcriptional regulator
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of NUPR1 mRNA
|
CTD |
PMID:15890375 PMID:23052194 |
|
NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901
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|
| G
|
Oat
|
ornithine aminotransferase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OAT mRNA
|
CTD |
PMID:14600272 PMID:22484513 |
|
NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754
|
|
| G
|
Obp1f
|
odorant binding protein I f
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of OBP1F mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr X:45,833,861...45,839,070
|
|
| G
|
Obp3
|
alpha-2u globulin PGCL4
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OBP3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675
|
|
| G
|
Ocln
|
occludin
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of OCLN protein
|
CTD |
PMID:30236600 |
|
NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
|
|
| G
|
Odc1
|
ornithine decarboxylase 1
|
increases activity increases expression multiple interactions
|
ISO EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of ODC1 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ODC1 mRNA tocopheryloxybutyric acid inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of ODC1 protein]; tocopheryloxybutyric acid inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ODC1 mRNA]
|
CTD |
PMID:11301052 PMID:15890375 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions decreases expression
|
ISO
|
NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein
|
CTD |
PMID:35435490 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PCNA mRNA]; NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PCNA protein
|
CTD |
PMID:15890375 PMID:16582591 PMID:16835749 PMID:35435490 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pcsk2
|
proprotein convertase subtilisin/kexin type 2
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of PCSK2 mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr 3:151,333,938...151,636,628
Ensembl chr 3:151,333,234...151,638,849
|
|
| G
|
Pdcd4
|
programmed cell death 4
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PDCD4 mRNA
|
CTD |
PMID:21873647 |
|
NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189
|
|
| G
|
Per1
|
period circadian regulator 1
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of PER1 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of PER1 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211
|
|
| G
|
Pgd
|
phosphogluconate dehydrogenase
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PGD mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
|
|
| G
|
Phgdh
|
phosphoglycerate dehydrogenase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHGDH mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
|
|
| G
|
Phlda3
|
pleckstrin homology-like domain, family A, member 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PHLDA3 mRNA
|
CTD |
PMID:22484513 PMID:23052194 |
|
NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621
|
|
| G
|
Pla2g2a
|
phospholipase A2 group IIA
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLA2G2A mRNA
|
CTD |
PMID:24835565 |
|
NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
|
|
| G
|
Pla2g4a
|
phospholipase A2 group 4A
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLA2G4A mRNA
|
CTD |
PMID:24835565 |
|
NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641
|
|
| G
|
Plau
|
plasminogen activator, urokinase
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PLAU mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of PLAU mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030
|
|
| G
|
Plk2
|
polo-like kinase 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLK2 mRNA
|
CTD |
PMID:23052194 |
|
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
|
|
| G
|
Pln
|
phospholamban
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PLN mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241
|
|
| G
|
Por
|
cytochrome p450 oxidoreductase
|
affects response to substance
|
ISO
|
POR affects the susceptibility to 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:22710403 |
|
NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
|
|
| G
|
Prdx6
|
peroxiredoxin 6
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PRDX6 protein
|
CTD |
PMID:23692979 |
|
NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657
|
|
| G
|
Psma1
|
proteasome 20S subunit alpha 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949
|
|
| G
|
Psma2
|
proteasome 20S subunit alpha 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA2 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr17:55,250,054...55,260,441
Ensembl chr17:55,247,442...55,339,673
|
|
| G
|
Psma4
|
proteasome 20S subunit alpha 4
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA4 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979
|
|
| G
|
Psma5
|
proteasome 20S subunit alpha 5
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PSMA5 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867
|
|
| G
|
Psma7
|
proteasome 20S subunit alpha 7
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMA7 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253
|
|
| G
|
Psmb1
|
proteasome 20S subunit beta 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640
|
|
| G
|
Psmb3
|
proteasome 20S subunit beta 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883
|
|
| G
|
Psmb4
|
proteasome 20S subunit beta 4
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB4 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287
|
|
| G
|
Psmb5
|
proteasome 20S subunit beta 5
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMB5 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379
|
|
| G
|
Psmc1
|
proteasome 26S subunit, ATPase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858
|
|
| G
|
Psmc2
|
proteasome 26S subunit, ATPase 2
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC2 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390
|
|
| G
|
Psmc4
|
proteasome 26S subunit, ATPase 4
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC4 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060
|
|
| G
|
Psmc5
|
proteasome 26S subunit, ATPase 5
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMC5 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921
|
|
| G
|
Psmd1
|
proteasome 26S subunit, non-ATPase 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PSMD1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions increases activity
|
ISO
|
[4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased abundance of Dinoprostone]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; Propranolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; SB 203580 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]; U 0126 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of PTGS2 protein]
|
CTD |
PMID:15762874 PMID:18805435 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Ptk2
|
protein tyrosine kinase 2
|
multiple interactions
|
ISO
|
[Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of PTK2 protein
|
CTD |
PMID:30259641 |
|
NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
|
|
| G
|
Ptp4a1
|
protein tyrosine phosphatase 4A1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PTP4A1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
|
|
| G
|
Ptprv
|
protein tyrosine phosphatase, receptor type, V
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of PTPRV mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr13:49,099,922...49,120,247
Ensembl chr13:49,099,925...49,120,121
|
|
| G
|
Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PTTG1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
|
|
| G
|
R3hdm2
|
R3H domain containing 2
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of R3HDM2 mRNA
|
CTD |
PMID:22484513 |
|
NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862
|
|
| G
|
Rad23b
|
RAD23 homolog B, nucleotide excision repair protein
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RAD23B mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426
|
|
| G
|
Raf1
|
Raf-1 proto-oncogene, serine/threonine kinase
|
increases activity
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of RAF1 protein
|
CTD |
PMID:17459420 |
|
NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813
|
|
| G
|
Rarb
|
retinoic acid receptor, beta
|
increases methylation
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased methylation of RARB promoter
|
CTD |
PMID:14656941 |
|
NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
multiple interactions decreases expression increases phosphorylation
|
ISO EXP
|
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RB1 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RB1 mRNA
|
CTD |
PMID:15890375 PMID:18805435 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of RELA protein
|
CTD |
PMID:18508827 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Rfx1
|
regulatory factor X1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RFX1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr19:40,966,102...40,996,809
Ensembl chr19:40,966,102...40,996,809
|
|
| G
|
Rgmb
|
repulsive guidance molecule BMP co-receptor b
|
multiple interactions
|
ISO
|
[Benzo(a)pyrene co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of RGMB mRNA
|
CTD |
PMID:20146248 |
|
NCBI chr 1:65,439,748...65,465,149
Ensembl chr 1:65,441,410...65,465,098
|
|
| G
|
Rhcg
|
Rh family, C glycoprotein
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of RHCG mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 1:142,941,046...142,965,242
Ensembl chr 1:142,941,048...142,965,376
|
|
| G
|
Rheb
|
Ras homolog, mTORC1 binding
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RHEB mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:11,012,643...11,053,931
|
|
| G
|
Rhob
|
ras homolog family member B
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RHOB mRNA
|
CTD |
PMID:14600272 PMID:22484513 |
|
NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772
|
|
| G
|
Rpl10
|
ribosomal protein L10
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL10 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr X:157,205,850...157,208,057
Ensembl chr X:157,205,836...157,208,049
|
|
| G
|
Rpl10a
|
ribosomal protein L10A
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL10A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091
|
|
| G
|
Rpl13
|
ribosomal protein L13
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL13 mRNA
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CTD |
PMID:15890375 |
|
NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059
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| G
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Rpl15
|
ribosomal protein L15
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL15 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308
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| G
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Rpl17
|
ribosomal protein L17
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL17 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638 Ensembl chr18:111,722,010...111,722,638
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| G
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Rpl23
|
ribosomal protein L23
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL23 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214
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| G
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Rpl6
|
ribosomal protein L6
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL6 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr12:41,008,142...41,012,756
Ensembl chr12:41,008,142...41,025,733
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| G
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Rpl7a
|
ribosomal protein L7A
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL7A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 3:30,637,136...30,639,778
Ensembl chr 3:30,637,059...30,639,791 Ensembl chr18:30,637,059...30,639,791
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| G
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Rpl8
|
ribosomal protein L8
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPL8 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103 Ensembl chr 3:110,506,800...110,509,103
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| G
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Rps15a
|
ribosomal protein S15a
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS15A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:181,854,396...181,861,330
Ensembl chr 1:181,854,396...181,861,201
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|
| G
|
Rps19
|
ribosomal protein S19
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS19 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132 Ensembl chr 1:104,324,520...104,325,132
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| G
|
Rps24
|
ribosomal protein S24
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS24 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr16:95,429...101,146
Ensembl chr16:96,484...101,144
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|
| G
|
Rps27l
|
ribosomal protein S27-like
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS27L mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 8:76,443,658...76,448,593
Ensembl chr12:33,713,661...33,714,130 Ensembl chr 8:33,713,661...33,714,130
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| G
|
Rps3
|
ribosomal protein S3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS3 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776
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|
| G
|
Rps4x
|
ribosomal protein S4, X-linked
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS4X mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr X:71,338,478...71,342,921
Ensembl chr X:71,338,479...71,342,921 Ensembl chr 4:71,338,479...71,342,921
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|
| G
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Rps6kb1
|
ribosomal protein S6 kinase B1
|
multiple interactions increases phosphorylation
|
ISO
|
[Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased phosphorylation of RPS6KB1 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of RPS6KB1 protein
|
CTD |
PMID:30259641 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
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| G
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Rps7
|
ribosomal protein S7
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPS7 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 6:50,994,581...50,999,447
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| G
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Rpsa
|
ribosomal protein SA
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RPSA mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737
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| G
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RT1-Bb
|
RT1 class II, locus Bb
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of RT1-BB mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118
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|
| G
|
S100a4
|
S100 calcium-binding protein A4
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of S100A4 mRNA [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in decreased expression of S100A4 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837
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|
| G
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Sds
|
serine dehydratase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SDS mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773
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|
| G
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Selenoo
|
selenoprotein O
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SELENOO mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 7:122,047,555...122,058,448
Ensembl chr 7:122,047,555...122,058,447
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|
| G
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Selenow
|
selenoprotein W
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SELENOW mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:85,727,631...85,732,703
Ensembl chr 1:85,727,632...85,732,703
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|
| G
|
Serpina7
|
serpin family A member 7
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SERPINA7 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr X:107,452,044...107,510,958
Ensembl chr X:107,452,044...107,457,681
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|
| G
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Slc19a2
|
solute carrier family 19 member 2
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 protein [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A2 protein] which results in decreased uptake of Thiamine
|
CTD |
PMID:24244374 |
|
NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315
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|
| G
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Slc19a3
|
solute carrier family 19 member 3
|
multiple interactions decreases expression
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 protein] which results in decreased uptake of Thiamine 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC19A3 protein
|
CTD |
PMID:24244374 |
|
NCBI chr 9:91,723,799...91,747,499
Ensembl chr 9:91,724,718...91,754,991
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|
| G
|
Slc9a9
|
solute carrier family 9 member A9
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SLC9A9 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 8:104,112,279...104,675,944
Ensembl chr 8:104,112,559...104,676,891
|
|
| G
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Smg1
|
SMG1, nonsense mediated mRNA decay associated PI3K related kinase
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SMG1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 1:181,876,134...181,977,894
Ensembl chr 1:181,876,134...181,977,894
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|
| G
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Smoc1
|
SPARC related modular calcium binding 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SMOC1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956
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|
| G
|
Snai2
|
snail family transcriptional repressor 2
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SNAI2 protein
|
CTD |
PMID:30236600 |
|
NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349
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|
| G
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Soat2
|
sterol O-acyltransferase 2
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of SOAT2 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 7:135,160,424...135,173,521
Ensembl chr 7:135,160,402...135,173,513
|
|
| G
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Sprr1b
|
small proline-rich protein 1B
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of SPRR1B mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in increased expression of SPRR1B mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 2:180,704,457...180,706,355
Ensembl chr 2:180,704,457...180,706,355
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|
| G
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Sptan1
|
spectrin, alpha, non-erythrocytic 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of SPTAN1 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889
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|
| G
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Stat1
|
signal transducer and activator of transcription 1
|
increases activity multiple interactions increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]; Bungarotoxins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STAT1 mRNA]; Mecamylamine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of STAT1 protein]
|
CTD |
PMID:16582591 PMID:16835749 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
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|
| G
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Stmn1
|
stathmin 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of STMN1 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
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|
| G
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Tap1
|
transporter 1, ATP binding cassette subfamily B member
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TAP1 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810
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|
| G
|
Tars1
|
threonyl-tRNA synthetase 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TARS1 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 2:62,095,978...62,114,802
Ensembl chr 2:62,087,763...62,114,802
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|
| G
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Tat
|
tyrosine aminotransferase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TAT mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482
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|
| G
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Tbrg4
|
transforming growth factor beta regulator 4
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TBRG4 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr14:85,696,738...85,704,691
Ensembl chr14:85,695,893...85,704,659
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|
| G
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Timm10b
|
translocase of inner mitochondrial membrane 10B
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMM10B mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 1:169,392,355...169,395,201
Ensembl chr 1:169,392,177...169,395,205
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|
| G
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Timp1
|
TIMP metallopeptidase inhibitor 1
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMP1 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
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|
| G
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Tmsb10
|
thymosin, beta 10
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TMSB10 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 4:106,568,080...106,569,210
|
|
| G
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Tnfaip3
|
TNF alpha induced protein 3
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TNFAIP3 mRNA
|
CTD |
PMID:21873647 |
|
NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979
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|
| G
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Tnfrsf8
|
TNF receptor superfamily member 8
|
multiple interactions
|
ISO
|
[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in decreased expression of TNFRSF8 mRNA; Catechin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone co-treated with Benzo(a)pyrene] results in decreased expression of TNFRSF8 mRNA]
|
CTD |
PMID:21882252 |
|
NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:162,406,387...162,451,620
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|
| G
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Top2a
|
DNA topoisomerase II alpha
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TOP2A mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
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|
| G
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Tp53
|
tumor protein p53
|
multiple interactions increases expression increases ADP-ribosylation increases phosphorylation decreases expression affects localization
|
ISO
|
4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TP53 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite affects the localization of TP53 protein]; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone inhibits the reaction [sodium arsenite results in increased activity of TP53 protein] 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53 protein [Tetrachlorodibenzodioxin co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of TRP53 mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased ADP-ribosylation of TP53 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of TP53 protein 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone affects the localization of TP53 protein
|
CTD |
PMID:18805435 PMID:19931552 PMID:20421341 PMID:21167638 PMID:21776270 PMID:26231820 More...
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|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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|
| G
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Tp53bp1
|
tumor protein p53 binding protein 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TP53BP1 protein
|
CTD |
PMID:26231820 |
|
NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
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|
| G
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Tpd52
|
tumor protein D52
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TPD52 mRNA
|
CTD |
PMID:21873647 |
|
NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241
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| G
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Tsc22d1
|
TSC22 domain family, member 1
|
decreases expression
|
EXP ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TSC22D1 mRNA 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of TSC22 mRNA
|
CTD |
PMID:15890375 PMID:19038236 |
|
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
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|
| G
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Tuba1c
|
tubulin, alpha 1C
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TUBA1C mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311
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|
| G
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Tubb5
|
tubulin, beta 5 class I
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TUBB5 mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
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|
| G
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Twist1
|
twist family bHLH transcription factor 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TWIST1 mRNA
|
CTD |
PMID:21167638 |
|
NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965
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|
| G
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Tyms
|
thymidylate synthetase
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TYMS mRNA
|
CTD |
PMID:14600272 PMID:15890375 PMID:23052194 |
|
NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097
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|
| G
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Uba52
|
ubiquitin A-52 residue ribosomal protein fusion product 1
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UBA52 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr16:18,952,583...18,954,780
|
|
| G
|
Ube2r2
|
ubiquitin-conjugating enzyme E2R 2
|
increases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UBE2R2 mRNA
|
CTD |
PMID:19038236 |
|
NCBI chr 5:61,082,552...61,141,099
Ensembl chr 5:61,082,552...61,141,452
|
|
| G
|
Ugt1a5
|
UDP glucuronosyltransferase family 1 member A5
|
increases glucuronidation
|
ISO
|
UGT1A4 gene polymorphism results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; UGT1A4 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:14871856 PMID:31307193 |
|
NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Ugt1a7c
|
UDP glucuronosyltransferase 1 family, polypeptide A7C
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of UGT1A7 mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr 9:96,187,382...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Ugt1a9
|
UDP glucuronosyltransferase family 1 member A9
|
increases glucuronidation
|
ISO
|
UGT1A9 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:31307193 |
|
NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Ugt2b1
|
UDP glucuronosyltransferase 2 family, polypeptide B1
|
increases glucuronidation
|
ISO
|
UGT2B17 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:31307193 |
|
NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
|
|
| G
|
Ugt2b7
|
UDP glucuronosyltransferase family 2 member B7
|
decreases glucuronidation increases glucuronidation
|
ISO
|
UGT2B7 gene polymorphism results in decreased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone UGT2B7 protein results in increased glucuronidation of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
|
CTD |
PMID:14871856 PMID:31307193 |
|
NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of VEGFA mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
| G
|
Vim
|
vimentin
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of VIM mRNA
|
CTD |
PMID:14600272 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
|
|
| G
|
Xdh
|
xanthine dehydrogenase
|
decreases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XDH mRNA
|
CTD |
PMID:15890375 |
|
NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
|
|
| G
|
Xiap
|
X-linked inhibitor of apoptosis
|
increases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of XIAP protein [Nicotine co-treated with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] results in increased expression of XIAP protein
|
CTD |
PMID:30259641 |
|
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978
|
|
| G
|
Xpo1
|
exportin 1
|
decreases expression
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XPO1 protein
|
CTD |
PMID:20421341 |
|
NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714
|
|
| G
|
Xrcc1
|
X-ray repair cross complementing 1
|
decreases expression multiple interactions
|
ISO
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 mRNA; 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XRCC1 protein]
|
CTD |
PMID:35435490 |
|
NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
|
|
| G
|
Zmat3
|
zinc finger, matrin type 3
|
increases expression
|
EXP
|
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of ZMAT3 mRNA
|
CTD |
PMID:14600272 PMID:15890375 |
|
NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:117,034,517...117,065,294
|
|
|
|
| G
|
Atr
|
ATR serine/threonine kinase
|
multiple interactions decreases activity
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased phosphorylation of ATR protein]; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Cisplatin; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Hydroxyurea; [4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine results in decreased activity of ATR] which results in increased susceptibility to Temozolomide
|
CTD |
PMID:21730979 PMID:25748550 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Casp7
|
caspase 7
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP7 protein]
|
CTD |
PMID:26208482 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
|
|
| G
|
Casp8
|
caspase 8
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP8 protein]
|
CTD |
PMID:26208482 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
| G
|
Casp9
|
caspase 9
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased cleavage of CASP9 protein]
|
CTD |
PMID:26208482 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK1 protein]
|
CTD |
PMID:26208482 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein]
|
CTD |
PMID:26208482 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions
|
ISO
|
[4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein
|
CTD |
PMID:26208482 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
ISO
|
4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of and results in increased stability of TNF mRNA]; 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [trovafloxacin results in increased expression of TNF protein] 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [[trovafloxacin co-treated with TNF protein] results in increased phosphorylation of ATR protein]
|
CTD |
PMID:24817034 PMID:25748550 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases expression multiple interactions
|
ISO
|
Carmustine results in increased expression of ABCB1 protein [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine
|
CTD |
PMID:11792417 PMID:15239124 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
affects response to substance
|
ISO
|
ABCC2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
affects response to substance
|
ISO
|
ABCG5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
|
|
| G
|
Acer2
|
alkaline ceramidase 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of ACER2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:106,437,796...106,488,583
|
|
| G
|
Acp3
|
acid phosphatase 3
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of ACP3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033
|
|
| G
|
Actc1
|
actin, alpha, cardiac muscle 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ACTC1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:121,266,291...121,271,827
|
|
| G
|
Actg2
|
actin gamma 2, smooth muscle
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ACTG2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295
|
|
| G
|
Actn1
|
actinin, alpha 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ACTN1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172
|
|
| G
|
Adam15
|
ADAM metallopeptidase domain 15
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ADAM15 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:177,052,363...177,062,879
Ensembl chr 2:177,052,363...177,062,849
|
|
| G
|
Adamts4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ADAMTS4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514
|
|
| G
|
Adcyap1
|
adenylate cyclase activating polypeptide 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ADCYAP1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383
|
|
| G
|
Adra1b
|
adrenoceptor alpha 1B
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ADRA1B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347
|
|
| G
|
Agr3
|
anterior gradient 3, protein disulphide isomerase family member
|
affects response to substance
|
ISO
|
AGR3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:58,370,701...58,393,944
Ensembl chr 6:58,370,701...58,399,859
|
|
| G
|
Agt
|
angiotensinogen
|
decreases response to substance
|
ISO
|
AGT protein mutant form results in decreased susceptibility to Carmustine; AGT protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:11034089 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Akr1b1
|
aldo-keto reductase family 1 member B1
|
affects response to substance
|
ISO
|
AKR1B1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
|
|
| G
|
Akr1c1
|
aldo-keto reductase family 1, member C1
|
affects response to substance
|
ISO
|
AKR1C1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
decreases phosphorylation multiple interactions affects response to substance
|
EXP ISO
|
Carmustine results in decreased phosphorylation of AKT1 protein LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein] AKT1 protein affects the susceptibility to Carmustine
|
CTD |
PMID:18430789 PMID:19860839 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Akt2
|
AKT serine/threonine kinase 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of AKT2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
|
|
| G
|
Alad
|
aminolevulinate dehydratase
|
decreases expression multiple interactions
|
ISO
|
Carmustine results in decreased expression of ALAD mRNA [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein
|
CTD |
PMID:15980968 PMID:19162187 |
|
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
|
|
| G
|
Alas2
|
5'-aminolevulinate synthase 2
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of ALAS2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043
|
|
| G
|
Aldh1a3
|
aldehyde dehydrogenase 1 family, member A3
|
affects response to substance
|
ISO
|
ALDH1A3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
|
|
| G
|
Aldh1a7
|
aldehyde dehydrogenase family 1, subfamily A7
|
increases expression
|
EXP
|
Carmustine results in increased expression of ALDH1A7 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
|
|
| G
|
Alox12
|
arachidonate 12-lipoxygenase, 12S type
|
affects response to substance decreases expression
|
ISO EXP
|
ALOX12 protein affects the susceptibility to Carmustine Carmustine results in decreased expression of ALOX12 mRNA
|
CTD |
PMID:16005536 PMID:19373248 |
|
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
|
|
| G
|
Alox15b
|
arachidonate 15-lipoxygenase, type B
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ALOX15B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:54,391,331...54,400,648
Ensembl chr10:54,391,302...54,400,648
|
|
| G
|
Amh
|
anti-Mullerian hormone
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of AMH mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:9,557,451...9,559,867
|
|
| G
|
Ank2
|
ankyrin 2
|
affects response to substance
|
ISO
|
ANK2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259
|
|
| G
|
Ankrd1
|
ankyrin repeat domain 1
|
affects response to substance
|
ISO
|
ANKRD1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:243,228,460...243,237,014
Ensembl chr 1:243,228,448...243,263,751
|
|
| G
|
Ap1s2
|
adaptor related protein complex 1 subunit sigma 2
|
affects response to substance
|
ISO
|
AP1S2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr X:34,204,601...34,230,819
Ensembl chr X:34,204,603...34,228,529
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
affects response to substance
|
ISO
|
APC mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
Apc2
|
APC regulator of WNT signaling pathway 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of APC2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:10,043,010...10,065,037
Ensembl chr 7:10,043,010...10,065,210
|
|
| G
|
Apex1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
increases response to substance decreases response to substance
|
ISO
|
APEX1 protein mutant form results in increased susceptibility to Carmustine APEX1 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:12231548 PMID:16243814 PMID:17259346 PMID:19470598 |
|
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329
|
|
| G
|
Aplnr
|
apelin receptor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of APLNR mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:90,624,012...90,627,908
|
|
| G
|
Aqp8
|
aquaporin 8
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of AQP8 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242
|
|
| G
|
Arf1
|
ARF GTPase 1
|
affects response to substance
|
ISO
|
ARF1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:44,497,543...44,513,994
|
|
| G
|
Arpc2
|
actin related protein 2/3 complex, subunit 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ARPC2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:83,269,932...83,305,409
|
|
| G
|
Arrdc2
|
arrestin domain containing 2
|
affects response to substance
|
ISO
|
ARRDC2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158
|
|
| G
|
Artn
|
artemin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ARTN mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:136,750,188...136,755,645
Ensembl chr 5:136,750,188...136,753,457
|
|
| G
|
Asmtl
|
acetylserotonin O-methyltransferase-like
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ASMTL mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:21,429,119...21,431,847
Ensembl chr12:21,429,171...21,431,847
|
|
| G
|
Atp1a3
|
ATPase Na+/K+ transporting subunit alpha 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ATP1A3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:89,700,649...89,729,825
|
|
| G
|
Atp4b
|
ATPase H+/K+ transporting subunit beta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ATP4B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:82,846,329...82,855,242
Ensembl chr16:82,846,329...82,855,242
|
|
| G
|
Atp5f1d
|
ATP synthase F1 subunit delta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ATP5F1D mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583
|
|
| G
|
Atp6v0c
|
ATPase H+ transporting V0 subunit C
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ATP6V0C mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245
|
|
| G
|
Atr
|
ATR serine/threonine kinase
|
multiple interactions
|
ISO
|
ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]
|
CTD |
PMID:19261750 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Atxn2l
|
ataxin 2-like
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ATXN2L mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579
|
|
| G
|
Avpr1a
|
arginine vasopressin receptor 1A
|
increases expression
|
ISO
|
Carmustine results in increased expression of AVPR1A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837
|
|
| G
|
B4galt5
|
beta-1,4-galactosyltransferase 5
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of B4GALT5 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:176,437,073...176,488,978
|
|
| G
|
Baiap2
|
BAR/IMD domain containing adaptor protein 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BAIAP2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:105,721,371...105,788,549
Ensembl chr10:105,721,417...105,788,549
|
|
| G
|
Baiap3
|
BAI1-associated protein 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BAIAP3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:14,764,768...14,777,516
Ensembl chr10:14,756,693...14,777,516
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression
|
ISO
|
Carmustine results in increased expression of BAX protein
|
CTD |
PMID:20920327 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl10
|
BCL10, immune signaling adaptor
|
increases expression
|
ISO
|
Carmustine results in increased expression of BCL10 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions affects response to substance decreases expression
|
ISO
|
[Fenretinide co-treated with Carmustine] results in decreased expression of BCL2 protein BCL2 protein affects the susceptibility to Carmustine Carmustine results in decreased expression of BCL2 protein
|
CTD |
PMID:15332326 PMID:16187019 PMID:18430789 PMID:20920327 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l1
|
Bcl2-like 1
|
affects response to substance decreases expression multiple interactions
|
ISO EXP
|
BCL2L1 protein affects the susceptibility to Carmustine Carmustine results in decreased expression of BCL2L1 protein [Fenretinide co-treated with Carmustine] results in decreased expression of BCL2L1 protein Carmustine results in decreased expression of BCL2L1 mRNA; Carmustine results in decreased expression of BCL2L1 protein
|
CTD |
PMID:15332326 PMID:16187019 PMID:19860839 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
| G
|
Becn1
|
beclin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BECN1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
| G
|
Bicd1
|
BICD cargo adaptor 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BICD1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:184,210,363...184,357,391
|
|
| G
|
Blk
|
BLK proto-oncogene, Src family tyrosine kinase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BLK mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr15:41,802,701...41,841,004
Ensembl chr15:41,802,994...41,840,982
|
|
| G
|
Bmal1
|
basic helix-loop-helix ARNT like 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of BMAL1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
|
|
| G
|
Bmp5
|
bone morphogenetic protein 5
|
affects response to substance
|
ISO
|
BMP5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189
|
|
| G
|
Bmp7
|
bone morphogenetic protein 7
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BMP7 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137
|
|
| G
|
Brf1
|
BRF1 general transcription factor IIIB subunit
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of BRF1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386
|
|
| G
|
Ca6
|
carbonic anhydrase 6
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CA6 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:165,941,028...165,959,566
Ensembl chr 5:165,941,029...165,959,566
|
|
| G
|
Cadm1
|
cell adhesion molecule 1
|
affects response to substance
|
ISO
|
CADM1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
|
|
| G
|
Calb2
|
calbindin 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CALB2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952
|
|
| G
|
Casp3
|
caspase 3
|
increases activity multiple interactions increases cleavage increases expression
|
EXP ISO
|
Carmustine results in increased activity of CASP3 protein [Carmustine co-treated with 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid] results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; [LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Carmustine results in increased activity of and results in increased cleavage of CASP3 protein; pyrazolanthrone inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Zinc Sulfate inhibits the reaction [Carmustine results in increased activity of CASP3 protein] Carmustine results in increased expression of CASP3 protein
|
CTD |
PMID:18590702 PMID:19860839 PMID:20046642 PMID:20920327 PMID:21600974 PMID:24193513 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP
|
Carmustine results in decreased activity of CAT protein Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]
|
CTD |
PMID:20332008 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
affects activity affects response to substance increases expression decreases expression
|
ISO
|
Carmustine affects the activity of CCL2 protein CCL2 mRNA affects the susceptibility to Carmustine Carmustine results in increased expression of CCL2 mRNA Carmustine results in decreased expression of CCL2 protein
|
CTD |
PMID:15980968 PMID:16365179 PMID:17522861 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccn4
|
cellular communication network factor 4
|
affects response to substance
|
ISO
|
CCN4 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094
|
|
| G
|
Ccnd1
|
cyclin D1
|
affects response to substance
|
ISO
|
CCND1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccne1
|
cyclin E1
|
increases expression
|
EXP
|
Carmustine results in increased expression of CCNE1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
|
|
| G
|
Cd151
|
CD151 molecule (Raph blood group)
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CD151 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784
|
|
| G
|
Cd44
|
CD44 molecule
|
affects response to substance
|
ISO
|
CD44 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cd68
|
Cd68 molecule
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CD68 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540
|
|
| G
|
Cd79a
|
CD79a molecule
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CD79A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:89,621,460...89,625,813
Ensembl chr 1:89,621,460...89,625,812
|
|
| G
|
Cd80
|
Cd80 molecule
|
increases expression
|
ISO
|
Carmustine results in increased expression of CD80 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
|
|
| G
|
Cdc25b
|
cell division cycle 25B
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of CDC25B mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
|
|
| G
|
Cdh13
|
cadherin 13
|
affects response to substance
|
ISO
|
CDH13 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119
|
|
| G
|
Cdk8
|
cyclin-dependent kinase 8
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CDK8 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:13,851,024...13,919,017
Ensembl chr12:13,851,024...13,917,992
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
multiple interactions increases expression
|
ISO
|
[Carmustine co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein]
|
CTD |
PMID:15735757 PMID:16193384 PMID:18632648 PMID:20472715 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1c
|
cyclin-dependent kinase inhibitor 1C
|
affects response to substance
|
ISO
|
CDKN1C mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
|
|
| G
|
Cdkn2a
|
cyclin-dependent kinase inhibitor 2A
|
increases response to substance
|
ISO
|
CDKN2A protein results in increased susceptibility to Carmustine
|
CTD |
PMID:16786135 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
|
|
| G
|
Cdkn3
|
cyclin-dependent kinase inhibitor 3
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of CDKN3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
|
|
| G
|
Cdx4
|
caudal type homeo box 4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CDX4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:72,392,653...72,401,239
Ensembl chr X:72,392,653...72,401,239
|
|
| G
|
Cebpb
|
CCAAT/enhancer binding protein beta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CEBPB mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
|
|
| G
|
Cgref1
|
cell growth regulator with EF hand domain 1
|
increases expression
|
EXP
|
Carmustine results in increased expression of CGREF1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800
|
|
| G
|
Chd2
|
chromodomain helicase DNA binding protein 2
|
affects response to substance
|
ISO
|
CHD2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:136,597,993...136,726,874
Ensembl chr 1:136,599,900...136,710,335
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
multiple interactions
|
ISO
|
ATR protein affects the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Caffeine inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein; O(6)-benzylguanine promotes the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]; wortmannin inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein]
|
CTD |
PMID:19261750 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chrm4
|
cholinergic receptor, muscarinic 4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CHRM4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771
|
|
| G
|
Chrnb3
|
cholinergic receptor nicotinic beta 3 subunit
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CHRNB3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225
|
|
| G
|
Chrng
|
cholinergic receptor nicotinic gamma subunit
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CHRNG mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:95,325,984...95,332,092
Ensembl chr 9:95,325,984...95,332,092
|
|
| G
|
Ckm
|
creatine kinase, M-type
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CKM mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719
|
|
| G
|
Clic1
|
chloride intracellular channel 1
|
multiple interactions decreases response to substance
|
ISO
|
[4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CLIC1 protein] which results in increased susceptibility to Carmustine CLIC1 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:18590702 |
|
NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367
|
|
| G
|
Cntnap1
|
contactin associated protein 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of CNTNAP1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,611,890...86,631,730
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
affects response to substance
|
ISO
|
COL1A1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col5a3
|
collagen type V alpha 3 chain
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of COL5A3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 8:27,580,768...27,626,002
Ensembl chr 8:27,580,768...27,626,122
|
|
| G
|
Col9a1
|
collagen type IX alpha 1 chain
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of COL9A1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:34,081,364...34,164,552
Ensembl chr 9:34,003,905...34,164,543
|
|
| G
|
Cox6a2
|
cytochrome c oxidase subunit 6A2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of COX6A2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
|
|
| G
|
Crabp1
|
cellular retinoic acid binding protein 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CRABP1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:64,047,431...64,055,469
Ensembl chr 8:64,047,060...64,055,470
|
|
| G
|
Crat
|
carnitine O-acetyltransferase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CRAT mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
|
|
| G
|
Crybb1
|
crystallin, beta B1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CRYBB1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:50,030,146...50,043,756
Ensembl chr12:50,030,146...50,043,756
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
affects response to substance
|
ISO
|
CSF2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Csgalnact1
|
chondroitin sulfate N-acetylgalactosaminyltransferase 1
|
affects response to substance
|
ISO
|
CSGALNACT1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:25,761,946...26,097,306
Ensembl chr16:26,002,530...26,096,065
|
|
| G
|
Csrp3
|
cysteine and glycine rich protein 3
|
affects response to substance
|
ISO
|
CSRP3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:107,664,338...107,682,916
|
|
| G
|
Cst5
|
cystatin D
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CST5 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:158,033,791...158,038,345
Ensembl chr 3:158,033,791...158,038,345
|
|
| G
|
Ctf1
|
cardiotrophin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CTF1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395
|
|
| G
|
Ctnnal1
|
catenin alpha-like 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of CTNNAL1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637
|
|
| G
|
Ctsl
|
cathepsin L
|
increases expression
|
EXP
|
Carmustine results in increased expression of CTSL mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
| G
|
Cux2
|
cut-like homeobox 2
|
affects expression
|
EXP
|
Carmustine affects the expression of CUX2 mRNA
|
CTD |
PMID:19174181 |
|
NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528
|
|
| G
|
Cxcl1
|
C-X-C motif chemokine ligand 1
|
affects response to substance
|
ISO
|
CXCL1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
|
|
| G
|
Cxcl2
|
C-X-C motif chemokine ligand 2
|
affects response to substance
|
ISO
|
CXCL2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
affects response to substance
|
ISO
|
CXCL1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cyp19a1
|
cytochrome P450, family 19, subfamily a, polypeptide 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of CYP19A1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
|
|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions
|
ISO
|
CYP3A4 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
|
CTD |
PMID:16087946 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
multiple interactions
|
ISO
|
CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
|
CTD |
PMID:16087946 |
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Cyth1
|
cytohesin 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of CYTH1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:103,901,376...103,984,496
Ensembl chr10:103,864,804...103,984,383
|
|
| G
|
Def6
|
DEF6 guanine nucleotide exchange factor
|
affects response to substance
|
ISO
|
DEF6 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr20:6,270,323...6,291,724
Ensembl chr20:6,269,357...6,291,771
|
|
| G
|
Dhrs3
|
dehydrogenase/reductase 3
|
affects response to substance
|
ISO
|
DHRS3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653
|
|
| G
|
Dhx16
|
DEAH-box helicase 16
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of DHX16 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:2,866,804...2,879,790
Ensembl chr20:2,866,804...2,879,751
|
|
| G
|
Dhx37
|
DEAH-box helicase 37
|
affects response to substance
|
ISO
|
DHX37 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240
|
|
| G
|
Dkk1
|
dickkopf WNT signaling pathway inhibitor 1
|
increases response to substance
|
ISO
|
DKK1 protein results in increased susceptibility to Carmustine
|
CTD |
PMID:20920327 |
|
NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650
|
|
| G
|
Dmrtc2
|
DMRT-like family C2
|
affects response to substance
|
ISO
|
DMRTC2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:89,594,120...89,601,761
Ensembl chr 1:89,594,215...89,601,762
|
|
| G
|
Dnase1l2
|
deoxyribonuclease 1 like 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of DNASE1L2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:13,976,012...13,978,574
Ensembl chr10:13,976,012...13,978,366
|
|
| G
|
Dvl1
|
dishevelled segment polarity protein 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of DVL1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966
|
|
| G
|
Dyrk1b
|
dual specificity tyrosine phosphorylation regulated kinase 1B
|
affects response to substance
|
ISO
|
DYRK1B mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:92,606,743...92,624,089
Ensembl chr 1:92,607,303...92,614,744
|
|
| G
|
E2f1
|
E2F transcription factor 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of E2F1 protein
|
CTD |
PMID:18632648 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
|
|
| G
|
Ecm2
|
extracellular matrix protein 2
|
increases expression
|
ISO
|
Carmustine results in increased expression of ECM2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,326,359...15,358,855
|
|
| G
|
Ednra
|
endothelin receptor type A
|
affects response to substance
|
ISO
|
EDNRA mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284
|
|
| G
|
Eef1g
|
eukaryotic translation elongation factor 1 gamma
|
increases expression
|
ISO
|
Carmustine results in increased expression of EEF1G mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479
|
|
| G
|
Eif2b1
|
eukaryotic translation initiation factor 2B subunit alpha
|
increases expression
|
ISO
|
Carmustine results in increased expression of EIF2B1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:37,686,149...37,694,830
Ensembl chr12:37,686,559...37,708,078
|
|
| G
|
Eif4a2
|
eukaryotic translation initiation factor 4A2
|
affects response to substance
|
ISO
|
EIF4A2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr11:91,268,730...91,276,738
Ensembl chr11:91,268,731...91,275,323
|
|
| G
|
Eif6
|
eukaryotic translation initiation factor 6
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of EIF6 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525
|
|
| G
|
Elmo1
|
engulfment and cell motility 1
|
affects response to substance
|
ISO
|
ELMO1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:48,982,188...49,518,525
Ensembl chr17:48,982,188...49,518,159
|
|
| G
|
Enc1
|
ectodermal-neural cortex 1
|
increases expression
|
EXP
|
Carmustine results in increased expression of ENC1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of EPHX1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Espn
|
espin
|
increases expression
|
EXP
|
Carmustine results in increased expression of ESPN mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984
|
|
| G
|
Esrra
|
estrogen related receptor, alpha
|
increases expression
|
ISO
|
Carmustine results in increased expression of ESRRA mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
|
|
| G
|
Etv1
|
ETS variant transcription factor 1
|
affects response to substance affects expression
|
ISO EXP
|
ETV1 mRNA affects the susceptibility to Carmustine Carmustine affects the expression of ETV1 mRNA
|
CTD |
PMID:16365179 PMID:19174181 |
|
NCBI chr 6:61,316,836...61,408,985
Ensembl chr 6:61,317,429...61,408,959
|
|
| G
|
Extl1
|
exostosin-like glycosyltransferase 1
|
affects response to substance
|
ISO
|
EXTL1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:151,857,629...151,872,830
Ensembl chr 5:151,857,629...151,872,830
|
|
| G
|
Ezh2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of EZH2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183
|
|
| G
|
F3
|
coagulation factor III, tissue factor
|
increases expression
|
EXP
|
Carmustine results in increased expression of F3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
|
|
| G
|
Fancc
|
FA complementation group C
|
affects response to substance
|
ISO
|
FANCC mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096
|
|
| G
|
Fancd2
|
FA complementation group D2
|
increases ubiquitination affects localization
|
ISO
|
Carmustine results in increased ubiquitination of FANCD2 protein Carmustine affects the localization of FANCD2 protein
|
CTD |
PMID:17221219 |
|
NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035
|
|
| G
|
Fbln5
|
fibulin 5
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of FBLN5 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296
|
|
| G
|
Fbn1
|
fibrillin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of FBN1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283
|
|
| G
|
Fbxo32
|
F-box protein 32
|
affects response to substance
|
ISO
|
FBXO32 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491
|
|
| G
|
Fech
|
ferrochelatase
|
multiple interactions
|
ISO
|
[MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]
|
CTD |
PMID:12950064 |
|
NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546
|
|
| G
|
Fgf2
|
fibroblast growth factor 2
|
decreases response to substance
|
ISO
|
FGF2 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:20221717 |
|
NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493
|
|
| G
|
Fhl2
|
four and a half LIM domains 2
|
affects response to substance
|
ISO
|
FHL2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
|
|
| G
|
Fkbp1a
|
FKBP prolyl isomerase 1A
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of FKBP1A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233
|
|
| G
|
Fkbp5
|
FKBP prolyl isomerase 5
|
increases expression
|
EXP
|
Carmustine results in increased expression of FKBP5 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118
|
|
| G
|
Fnta
|
farnesyltransferase, CAAX box, subunit alpha
|
decreases expression increases expression
|
ISO
|
Carmustine results in decreased expression of FNTA mRNA Carmustine results in increased expression of FNTA mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:72,767,864...72,786,193
Ensembl chr16:72,767,627...72,788,229
|
|
| G
|
Foxf2
|
forkhead box F2
|
affects response to substance
|
ISO
|
FOXF2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:33,044,446...33,051,259
Ensembl chr17:32,846,603...33,051,259
|
|
| G
|
Foxj1
|
forkhead box J1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of FOXJ1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:102,065,163...102,069,945
Ensembl chr10:102,065,170...102,069,241
|
|
| G
|
Fth1
|
ferritin heavy chain 1
|
multiple interactions decreases response to substance decreases expression
|
ISO
|
Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of FTH1 mRNA] FTH1 results in decreased susceptibility to Carmustine Carmustine results in decreased expression of FTH1 mRNA
|
CTD |
PMID:15980968 PMID:16631525 PMID:21385903 |
|
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
|
|
| G
|
Ftl1
|
ferritin light chain 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of FTL mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:105,072,858...105,074,705
Ensembl chr X:45,399,355...45,399,915 Ensembl chr 2:45,399,355...45,399,915 Ensembl chr 1:45,399,355...45,399,915
|
|
| G
|
Fut8
|
fucosyltransferase 8
|
affects response to substance
|
ISO
|
FUT8 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:101,683,007...101,909,775
|
|
| G
|
Fyn
|
FYN proto-oncogene, Src family tyrosine kinase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of FYN mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
|
|
| G
|
Gabra2
|
gamma-aminobutyric acid type A receptor subunit alpha 2
|
decreases expression affects response to substance
|
ISO
|
Carmustine results in decreased expression of GABRA2 mRNA GABRA2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:15980968 PMID:16365179 |
|
NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,450,683...37,587,457
|
|
| G
|
Gabra6
|
gamma-aminobutyric acid type A receptor subunit alpha6
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GABRA6 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:27,311,965...27,327,337
Ensembl chr10:27,311,979...27,327,234
|
|
| G
|
Galnt15
|
polypeptide N-acetylgalactosaminyltransferase 15
|
affects response to substance
|
ISO
|
GALNT15 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285
|
|
| G
|
Gamt
|
guanidinoacetate N-methyltransferase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GAMT mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083
|
|
| G
|
Garnl3
|
GTPase activating Rap/RanGAP domain-like 3
|
affects response to substance
|
ISO
|
GARNL3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:36,686,388...36,830,011
Ensembl chr 3:36,686,389...36,830,020
|
|
| G
|
Gast
|
gastrin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GAST mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880
|
|
| G
|
Gclc
|
glutamate-cysteine ligase, catalytic subunit
|
multiple interactions
|
EXP
|
[Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GCLC protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GCLC protein
|
CTD |
PMID:12967637 PMID:16288907 |
|
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
|
|
| G
|
Gcm1
|
glial cells missing transcription factor 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of GCM1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:87,805,993...87,819,229
Ensembl chr 8:87,805,993...87,819,229
|
|
| G
|
Gdi1
|
GDP dissociation inhibitor 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of GDI1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:157,238,900...157,245,562
Ensembl chr X:157,238,892...157,245,560
|
|
| G
|
Gdi2
|
GDP dissociation inhibitor 2
|
increases expression
|
ISO
|
Carmustine results in increased expression of GDI2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147
|
|
| G
|
Gdnf
|
glial cell derived neurotrophic factor
|
decreases response to substance
|
ISO
|
GDNF protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:19138852 |
|
NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240
|
|
| G
|
Gfap
|
glial fibrillary acidic protein
|
decreases expression multiple interactions
|
ISO EXP
|
Carmustine results in decreased expression of GFAP mRNA Melatonin inhibits the reaction [Carmustine results in decreased expression of GFAP protein]
|
CTD |
PMID:15980968 PMID:17572393 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
|
|
| G
|
Ghsr
|
growth hormone secretagogue receptor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GHSR mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:112,196,767...112,201,181
|
|
| G
|
Glrb
|
glycine receptor, beta
|
affects response to substance
|
ISO
|
GLRB mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:168,432,736...168,505,614
Ensembl chr 2:168,432,736...168,505,614
|
|
| G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
increases expression
|
ISO
|
Carmustine results in increased expression of GNRHR mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr14:22,211,666...22,229,654
|
|
| G
|
Golga2
|
golgin A2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GOLGA2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:35,981,783...36,002,023
Ensembl chr 3:35,981,499...36,002,022
|
|
| G
|
Golga4
|
golgin A4
|
increases expression
|
ISO
|
Carmustine results in increased expression of GOLGA4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:127,085,830...127,163,227
Ensembl chr 8:127,085,848...127,163,603
|
|
| G
|
Gp1bb
|
glycoprotein Ib platelet subunit beta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GP1BB mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr11:95,882,561...95,883,738
|
|
| G
|
Gpr25
|
G protein-coupled receptor 25
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GPR25 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:50,264,516...50,266,422
Ensembl chr13:50,264,518...50,267,692
|
|
| G
|
Gpr32
|
G protein-coupled receptor 32
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GPR32 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:103,893,405...103,894,667
|
|
| G
|
Gpr37
|
G protein-coupled receptor 37
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GPR37 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:55,104,355...55,126,420
Ensembl chr 4:55,104,365...55,126,494
|
|
| G
|
Gpr65
|
G-protein coupled receptor 65
|
increases expression
|
ISO
|
Carmustine results in increased expression of GPR65 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:123,219,633...123,266,285
|
|
| G
|
Grb7
|
growth factor receptor bound protein 7
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GRB7 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,939,299...83,949,382
|
|
| G
|
Grn
|
granulin precursor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GRN mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
|
|
| G
|
Gsr
|
glutathione-disulfide reductase
|
multiple interactions decreases activity
|
ISO EXP
|
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Doxorubicin; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to zinc chloride; Glutathione Disulfide inhibits the reaction [Carmustine results in decreased activity of GSR protein]; NADP affects the reaction [Carmustine results in decreased activity of GSR protein] [Buthionine Sulfoximine co-treated with Carmustine] results in decreased activity of GSR protein; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of GSR protein; [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; Zinc Sulfate inhibits the reaction [Carmustine results in decreased activity of GSR protein] [[Carmustine results in decreased activity of GSR protein] which co-treated with Oligodeoxyribonucleotides analog] results in increased abundance of Glutathione Disulfide; [[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Carmustine results in decreased activity of GSR protein] which results in decreased susceptibility to chromium hexavalent ion; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein
|
CTD |
PMID:2116959 PMID:12114195 PMID:12433058 PMID:12477282 PMID:12632252 PMID:12967637 PMID:15104113 PMID:15321730 PMID:15720826 PMID:15857610 PMID:16160061 PMID:16288907 PMID:17382203 PMID:17498860 PMID:18155673 PMID:18528683 PMID:19401447 PMID:19668867 PMID:19856331 PMID:20046642 PMID:21600974 More...
|
|
NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
affects response to substance decreases response to substance multiple interactions
|
ISO
|
GSTM1 gene affects the susceptibility to Carmustine GSTM1 protein results in decreased susceptibility to Carmustine GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
|
CTD |
PMID:16087946 PMID:20067466 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Gstm2
|
glutathione S-transferase mu 2
|
decreases nitrosation
|
ISO
|
GSTM2 protein results in decreased nitrosation of Carmustine
|
CTD |
PMID:11841793 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
| G
|
Gstm5
|
glutathione S-transferase, mu 5
|
multiple interactions affects metabolic processing decreases nitrosation
|
ISO
|
GSTM3 protein results in decreased nitrosation of and results in decreased activity of Carmustine GSTM3 protein affects the metabolism of Carmustine GSTM3 protein results in decreased nitrosation of Carmustine
|
CTD |
PMID:8395980 PMID:11841793 PMID:15247628 |
|
NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions decreases response to substance
|
ISO
|
GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan] GSTP1 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:12791655 PMID:16899598 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
affects response to substance affects metabolic processing decreases nitrosation
|
ISO
|
GSTT1 protein affects the susceptibility to Carmustine GSTT1 protein affects the metabolism of Carmustine GSTT1 protein results in decreased nitrosation of Carmustine
|
CTD |
PMID:11841793 PMID:16874663 PMID:17827337 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
Gtf2f1
|
general transcription factor IIF subunit 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of GTF2F1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:1,931,033...1,940,197
Ensembl chr 9:1,930,055...1,940,197
|
|
| G
|
Gucy1b2
|
guanylate cyclase 1 soluble subunit beta 2
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of GUCY1B2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr15:40,774,907...40,845,463
Ensembl chr15:40,774,906...40,845,463
|
|
| G
|
H2ax
|
H2A.X variant histone
|
decreases expression increases phosphorylation multiple interactions affects localization
|
ISO
|
Carmustine results in decreased expression of H2AX mRNA Carmustine results in increased phosphorylation of H2AX protein MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein]
|
CTD |
PMID:15980968 PMID:20472715 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hacl1
|
2-hydroxyacyl-CoA lyase 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of HACL1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410
|
|
| G
|
Hadh
|
hydroxyacyl-CoA dehydrogenase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HADH mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
|
|
| G
|
Hagh
|
hydroxyacyl glutathione hydrolase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HAGH mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:14,379,400...14,394,046
Ensembl chr10:14,382,410...14,394,043
|
|
| G
|
Hcfc1
|
host cell factor C1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HCFC1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:156,839,100...156,864,132
Ensembl chr X:156,839,100...156,863,813
|
|
| G
|
Hhat
|
hedgehog acyltransferase
|
affects response to substance
|
ISO
|
HHAT mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr13:106,558,635...106,814,723
Ensembl chr13:106,541,866...106,811,563
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
decreases response to substance multiple interactions
|
EXP
|
HIF1A protein results in decreased susceptibility to Carmustine [cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine; [Deferoxamine results in increased activity of HIF1A protein] which results in decreased susceptibility to Carmustine
|
CTD |
PMID:14980978 PMID:15965067 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
|
|
| G
|
Hmgn2
|
high mobility group nucleosomal binding domain 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HMGN2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:151,475,907...151,479,361
Ensembl chr 5:151,475,909...151,479,397
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
multiple interactions
|
ISO
|
Carmustine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]
|
CTD |
PMID:16631525 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hnf1a
|
HNF1 homeobox A
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HNF1A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755
|
|
| G
|
Hoxa4
|
homeo box A4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of HOXA4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:82,620,294...82,622,302
Ensembl chr 4:82,620,299...82,622,302
|
|
| G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
increases mutagenesis
|
ISO
|
Carmustine results in increased mutagenesis of HPRT1 gene
|
CTD |
PMID:17116724 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Icam5
|
intercellular adhesion molecule 5
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ICAM5 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:27,843,563...27,851,767
Ensembl chr 8:27,844,780...27,857,104
|
|
| G
|
Ids
|
iduronate 2-sulfatase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of IDS mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:154,070,781...154,093,681
Ensembl chr X:154,070,781...154,091,444
|
|
| G
|
Ier3
|
immediate early response 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of IER3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
decreases expression increases expression
|
ISO
|
Carmustine results in decreased expression of IGF1 protein Carmustine results in increased expression of IGF1 protein
|
CTD |
PMID:15286697 PMID:18443378 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Igf2
|
insulin-like growth factor 2
|
affects response to substance
|
ISO
|
IGF2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667
|
|
| G
|
Igfbp3
|
insulin-like growth factor binding protein 3
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of IGFBP3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944
|
|
| G
|
Ikbkg
|
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of IKBKG mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757
|
|
| G
|
Il12b
|
interleukin 12B
|
multiple interactions
|
ISO
|
Carmustine promotes the reaction [Lipopolysaccharides results in increased expression of IL12B protein]
|
CTD |
PMID:12688424 |
|
NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
|
|
| G
|
Il1b
|
interleukin 1 beta
|
multiple interactions
|
EXP
|
Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
|
CTD |
PMID:11970852 PMID:12433058 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il1r1
|
interleukin 1 receptor type 1
|
affects response to substance
|
ISO
|
IL1R1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
|
|
| G
|
Il6
|
interleukin 6
|
affects response to substance multiple interactions
|
ISO EXP
|
IL6 mRNA affects the susceptibility to Carmustine Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of IL6 protein]
|
CTD |
PMID:11970852 PMID:12433058 PMID:12477282 PMID:16365179 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Inhba
|
inhibin subunit beta A
|
affects response to substance
|
ISO
|
INHBA mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508
|
|
| G
|
Inppl1
|
inositol polyphosphate phosphatase-like 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of INPPL1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:165,595,063...165,609,503
|
|
| G
|
Insig1
|
insulin induced gene 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of INSIG1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
|
|
| G
|
Insl3
|
insulin-like 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of INSL3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:18,432,668...18,434,539
|
|
| G
|
Ipo4
|
importin 4
|
affects response to substance
|
ISO
|
IPO4 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241
|
|
| G
|
Irag2
|
inositol 1,4,5-triphosphate receptor associated 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of IRAG2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:179,819,526...179,874,408
Ensembl chr 4:179,820,188...179,874,406
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of IRS1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Islr
|
immunoglobulin superfamily containing leucine-rich repeat
|
decreases expression
|
ISO EXP
|
Carmustine results in decreased expression of ISLR mRNA
|
CTD |
PMID:15980968 PMID:16005536 |
|
NCBI chr 8:67,467,013...67,469,989
Ensembl chr 8:67,444,536...67,487,493
|
|
| G
|
Itga3
|
integrin subunit alpha 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ITGA3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901
|
|
| G
|
Itgb1
|
integrin subunit beta 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ITGB1 protein
|
CTD |
PMID:18443378 |
|
NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269
|
|
| G
|
Itgb3
|
integrin subunit beta 3
|
increases response to substance multiple interactions
|
ISO EXP
|
ITGB3 protein results in increased susceptibility to Carmustine 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [ITGB3 protein results in increased susceptibility to Carmustine]
|
CTD |
PMID:21332719 |
|
NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800
|
|
| G
|
Itih1
|
inter-alpha trypsin inhibitor, heavy chain 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ITIH1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853
|
|
| G
|
Kcna4
|
potassium voltage-gated channel subfamily A member 4
|
multiple interactions
|
EXP
|
[Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCNA4 protein
|
CTD |
PMID:16288907 |
|
NCBI chr 3:114,211,091...114,218,545
Ensembl chr 3:114,210,998...114,344,932
|
|
| G
|
Kcnab2
|
potassium voltage-gated channel subfamily A regulatory beta subunit 2
|
affects response to substance
|
ISO
|
KCNAB2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:168,182,228...168,270,760
Ensembl chr 5:168,184,613...168,270,760
|
|
| G
|
Kcnd2
|
potassium voltage-gated channel subfamily D member 2
|
multiple interactions
|
EXP
|
[Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 mRNA; [Carmustine co-treated with Buthionine Sulfoximine] results in decreased expression of KCND2 protein
|
CTD |
PMID:16288907 |
|
NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522
|
|
| G
|
Kcnh2
|
potassium voltage-gated channel subfamily H member 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of KCNH2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421
|
|
| G
|
Kif2c
|
kinesin family member 2C
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of KIF2C mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212
|
|
| G
|
Kif5a
|
kinesin family member 5A
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of KIF5A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:64,937,210...64,974,339
Ensembl chr 7:64,934,740...64,978,272
|
|
| G
|
Krt17
|
keratin 17
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of KRT17 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787
|
|
| G
|
Krt31
|
keratin 31
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of KRT31 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:85,479,533...85,483,300
Ensembl chr10:85,479,796...85,483,300
|
|
| G
|
Krt8
|
keratin 8
|
affects response to substance
|
ISO
|
KRT8 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Lad1
|
ladinin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of LAD1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709
|
|
| G
|
Lair1
|
leukocyte-associated immunoglobulin-like receptor 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of LAIR1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:79,140,850...79,261,546
Ensembl chr 1:79,198,311...79,258,037
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of LAMB3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lbp
|
lipopolysaccharide binding protein
|
affects response to substance
|
ISO
|
LBP mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
|
|
| G
|
Lcn2
|
lipocalin 2
|
increases response to substance multiple interactions
|
ISO EXP
|
LCN2 protein results in increased susceptibility to Carmustine [LCN2 protein co-treated with Carmustine] results in increased cleavage of and results in increased activity of CASP3 protein; LCN2 protein promotes the reaction [Carmustine results in decreased phosphorylation of AKT1 protein]
|
CTD |
PMID:19860839 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Ldlr
|
low density lipoprotein receptor
|
affects uptake
|
ISO
|
LDLR protein affects the uptake of Carmustine analog
|
CTD |
PMID:12107554 |
|
NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675
|
|
| G
|
Lif
|
LIF, interleukin 6 family cytokine
|
increases response to substance
|
ISO
|
LIF mRNA results in increased susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053
|
|
| G
|
Lig1
|
DNA ligase 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of LIG1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
| G
|
Lins1
|
lines homolog 1
|
affects response to substance
|
ISO
|
LINS1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:129,677,815...129,705,399
Ensembl chr 1:129,692,225...129,703,826
|
|
| G
|
Lman1l
|
lectin, mannose-binding, 1 like
|
affects response to substance
|
ISO
|
LMAN1L mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:66,906,684...66,925,512
Ensembl chr 8:66,906,624...66,919,584
|
|
| G
|
Lmtk2
|
lemur tyrosine kinase 2
|
affects response to substance
|
ISO
|
LMTK2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:15,540,428...15,622,392
Ensembl chr12:15,540,428...15,622,392
|
|
| G
|
Lmx1b
|
LIM homeobox transcription factor 1 beta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of LMX1B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:37,257,025...37,338,675
Ensembl chr 3:37,259,855...37,338,557
|
|
| G
|
Loxl1
|
lysyl oxidase-like 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of LOXL1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:67,587,636...67,612,224
Ensembl chr 8:67,587,636...67,612,224
|
|
| G
|
Lrch4
|
leucine rich repeats and calponin homology domain containing 4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of LRCH4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:24,694,364...24,709,354
Ensembl chr12:24,694,370...24,706,412
|
|
| G
|
Lsp1
|
lymphocyte-specific protein 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of LSP1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:207,044,157...207,077,891
Ensembl chr 1:207,044,159...207,077,893
|
|
| G
|
Mad1l1
|
mitotic arrest deficient 1 like 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MAD1L1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567
|
|
| G
|
Map4k2
|
mitogen activated protein kinase kinase kinase kinase 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MAP4K2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987
|
|
| G
|
Mapk10
|
mitogen activated protein kinase 10
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MAPK10 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100
|
|
| G
|
Masp1
|
MBL associated serine protease 1
|
affects response to substance
|
ISO
|
MASP1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470
|
|
| G
|
Mat1a
|
methionine adenosyltransferase 1A
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MAT1A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:17,017,168...17,035,368
Ensembl chr16:17,016,030...17,035,367
|
|
| G
|
Mdk
|
midkine
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MDK mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743
|
|
| G
|
Mdm4
|
MDM4 regulator of p53
|
multiple interactions decreases response to substance
|
ISO
|
[Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein; MDM4 protein promotes the reaction [Carmustine affects the localization of H2AX protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein]; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein]; MDM4 protein promotes the reaction [Carmustine results in increased phosphorylation of H2AX protein] MDM4 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:20472715 |
|
NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
|
|
| G
|
Mecom
|
MDS1 and EVI1 complex locus
|
affects response to substance
|
ISO
|
MECOM mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038
|
|
| G
|
Med1
|
mediator complex subunit 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MED1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545
|
|
| G
|
Meg3
|
maternally expressed 3
|
affects response to substance
|
ISO
|
MEG3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:134,274,056...134,306,249
|
|
| G
|
Mgat3
|
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MGAT3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:113,614,011...113,640,201
Ensembl chr 7:113,598,059...113,643,481
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
increases alkylation increases response to substance multiple interactions decreases expression decreases response to substance affects response to substance decreases activity
|
ISO EXP
|
Carmustine results in increased alkylation of MGMT protein MGMT mutant form results in increased susceptibility to Carmustine [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Carmustine; [MGMT protein mutant form co-treated with FECH protein] results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; [O(6)-benzyl-2'-deoxyguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzyl-N-acetylguanosine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [O(6)-benzylguanine co-treated with Carmustine] results in decreased activity of MGMT protein; [O(6)-benzylguanine results in decreased activity of MGMT protein] which results in increased susceptibility to Carmustine; [Tamoxifen results in increased degradation of MGMT protein] which results in increased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein mutant form results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [O(6)-benzylguanine co-treated with Carmustine]; O(6)-benzylguanine inhibits the reaction [MGMT protein mutant form results in decreased susceptibility to Carmustine] Carmustine results in decreased expression of MGMT protein MGMT protein results in decreased susceptibility to Carmustine [O(6)-benzylguanine results in decreased activity of MGMT protein] which affects the susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine]; MGMT protein results in decreased susceptibility to [Carmustine co-treated with O(6)-benzylguanine] MGMT protein affects the susceptibility to Carmustine Carmustine results in decreased activity of MGMT protein MGMT mRNA results in decreased susceptibility to Carmustine; MGMT protein mutant form results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine; MGMT protein results in decreased susceptibility to Carmustine analog; MGMT results in decreased susceptibility to Carmustine MGMT gene modified form affects the susceptibility to Carmustine; MGMT promoter modified form affects the susceptibility to Carmustine; MGMT protein affects the susceptibility to Carmustine
|
CTD |
PMID:8823159 PMID:9918549 PMID:11792417 PMID:11945064 PMID:12036916 PMID:12394182 PMID:12479369 PMID:12684420 PMID:12950064 PMID:14506174 PMID:14617757 PMID:14670122 PMID:14707273 PMID:14742745 PMID:15104113 PMID:15284838 PMID:15319033 PMID:15814657 PMID:15833865 PMID:16033832 PMID:16039682 PMID:16126841 PMID:16278409 PMID:16365179 PMID:16405512 PMID:16432170 PMID:16899598 PMID:16927363 PMID:17597106 PMID:18430789 PMID:18492797 PMID:19415780 PMID:19637364 PMID:19844954 PMID:20450874 PMID:20556481 PMID:20654586 PMID:26208482 More...
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|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Mgst2
|
microsomal glutathione S-transferase 2
|
affects response to substance
|
ISO
|
MGST2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
|
|
| G
|
Mlh1
|
mutL homolog 1
|
affects response to substance
|
ISO
|
MLH1 protein affects the susceptibility to Carmustine
|
CTD |
PMID:18430789 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
|
|
| G
|
Mlph
|
melanophilin
|
affects response to substance
|
ISO
|
MLPH mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 9:98,955,036...98,990,566
Ensembl chr 9:98,955,141...98,990,556
|
|
| G
|
Mpg
|
N-methylpurine-DNA glycosylase
|
decreases response to substance
|
ISO
|
MPG protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:16288039 |
|
NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052
|
|
| G
|
Mpst
|
mercaptopyruvate sulfurtransferase
|
affects response to substance
|
ISO
|
MPST mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650
|
|
| G
|
Msh2
|
mutS homolog 2
|
affects response to substance
|
ISO
|
MSH2 protein affects the susceptibility to Carmustine
|
CTD |
PMID:18430789 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
|
|
| G
|
Msr1
|
macrophage scavenger receptor 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MSR1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070
|
|
| G
|
Mt2
|
metallothionein 2
|
affects response to substance multiple interactions
|
ISO EXP
|
MT2A mRNA affects the susceptibility to Carmustine MT2 protein inhibits the reaction [Carmustine results in decreased activity of GSR protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein] MT2 protein affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 PMID:18528683 |
|
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
|
|
| G
|
Mturn
|
maturin, neural progenitor differentiation regulator homolog
|
affects response to substance
|
ISO
|
MTURN mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:85,137,825...85,158,790
Ensembl chr 4:85,137,846...85,158,789
|
|
| G
|
Muc2
|
mucin 2, oligomeric mucus/gel-forming
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MUC2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280
|
|
| G
|
Mug2
|
murinoglobulin 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PZP mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:156,836,140...156,908,972
|
|
| G
|
Mvd
|
mevalonate diphosphate decarboxylase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MVD mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366
|
|
| G
|
Mybl2
|
MYB proto-oncogene like 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of MYBL2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221
|
|
| G
|
Mybph
|
myosin binding protein H
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MYBPH mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928
|
|
| G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MYD88 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
|
|
| G
|
Myod1
|
myogenic differentiation 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MYOD1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:106,021,161...106,023,871
Ensembl chr 1:106,021,161...106,023,871
|
|
| G
|
Myog
|
myogenin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of MYOG mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:48,297,476...48,300,065
Ensembl chr13:48,297,235...48,300,065
|
|
| G
|
Nbl1
|
NBL1, DAN family BMP antagonist
|
affects response to substance
|
ISO
|
NBL1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:156,601,986...156,613,186
|
|
| G
|
Ndufc1
|
NADH:ubiquinone oxidoreductase subunit C1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of NDUFC1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:137,597,944...137,601,819
Ensembl chr 2:137,600,156...137,601,735
|
|
| G
|
Nek6
|
NIMA-related kinase 6
|
increases expression
|
EXP
|
Carmustine results in increased expression of NEK6 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 3:42,693,994...42,766,026
Ensembl chr 3:42,693,971...42,767,773
|
|
| G
|
Nes
|
nestin
|
increases expression multiple interactions
|
EXP
|
Carmustine results in increased expression of NES protein Melatonin inhibits the reaction [Carmustine results in increased expression of NES protein]
|
CTD |
PMID:17572393 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
|
|
| G
|
Nfat5
|
nuclear factor of activated T-cells 5
|
affects response to substance
|
ISO
|
NFAT5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418
|
|
| G
|
Nfe2l2
|
NFE2 like bZIP transcription factor 2
|
affects response to substance
|
ISO
|
[NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Carmustine
|
CTD |
PMID:19303893 |
|
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
|
|
| G
|
Nfib
|
nuclear factor I/B
|
affects response to substance
|
ISO
|
NFIB mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945
|
|
| G
|
Nfix
|
nuclear factor I X
|
affects response to substance
|
ISO
|
NFIX mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092
|
|
| G
|
Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions
|
ISO EXP
|
Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]] Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] [Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]; [Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
|
CTD |
PMID:11970852 PMID:12433058 PMID:12477282 PMID:12675310 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions increases response to substance
|
ISO EXP
|
NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]] Carmustine inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] NFKBIA gene mutant form results in increased susceptibility to Carmustine; NFKBIA mRNA results in increased susceptibility to Carmustine
|
CTD |
PMID:11970852 PMID:12433058 PMID:12675310 PMID:16365179 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
| G
|
Ngef
|
neuronal guanine nucleotide exchange factor
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of NGEF mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:95,594,823...95,692,251
|
|
| G
|
Ngf
|
nerve growth factor
|
affects activity
|
EXP
|
Carmustine affects the activity of NGF protein
|
CTD |
PMID:15935206 |
|
NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
|
|
| G
|
Nid2
|
nidogen 2
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of NID2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949
|
|
| G
|
Nin
|
ninein
|
affects response to substance
|
ISO
|
NIN mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:94,261,382...94,363,679
Ensembl chr 6:94,263,206...94,363,610
|
|
| G
|
Nkd2
|
NKD inhibitor of WNT signaling pathway 2
|
affects response to substance
|
ISO
|
NKD2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:31,268,856...31,299,390
Ensembl chr 1:31,272,519...31,299,387
|
|
| G
|
Nkx2-2
|
NK2 homeobox 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of NKX2-2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:155,072,621...155,083,699
Ensembl chr 3:155,073,250...155,083,249
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
multiple interactions decreases response to substance
|
ISO EXP
|
[NOS2 protein results in increased chemical synthesis of S-Nitrosoglutathione] which results in decreased susceptibility to Carmustine NOS2 protein results in decreased susceptibility to Carmustine [Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]
|
CTD |
PMID:7532384 PMID:15110396 PMID:15965067 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Npas1
|
neuronal PAS domain protein 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of NPAS1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:86,295,509...86,316,018
Ensembl chr 1:86,295,515...86,314,893
|
|
| G
|
Npas2
|
neuronal PAS domain protein 2
|
affects response to substance
|
ISO
|
NPAS2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037
|
|
| G
|
Npl
|
N-acetylneuraminate pyruvate lyase
|
affects response to substance
|
ISO
|
NPL mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr13:68,205,602...68,247,940
Ensembl chr13:68,205,603...68,247,999
|
|
| G
|
Npr1
|
natriuretic peptide receptor 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of NPR1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088
|
|
| G
|
Nr2f1
|
nuclear receptor subfamily 2, group F, member 1
|
affects response to substance
|
ISO
|
NR2F1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:9,776,179...9,785,924
|
|
| G
|
Nr4a2
|
nuclear receptor subfamily 4, group A, member 2
|
affects expression
|
EXP
|
Carmustine affects the expression of NR4A2 mRNA
|
CTD |
PMID:19174181 |
|
NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769
|
|
| G
|
Nrtn
|
neurturin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of NRTN mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,641,618...1,675,133
|
|
| G
|
Ogg1
|
8-oxoguanine DNA glycosylase
|
decreases response to substance
|
ISO
|
OGG1 protein results in decreased susceptibility to Carmustine
|
CTD |
PMID:11181913 PMID:11741815 |
|
NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604
|
|
| G
|
Omp
|
olfactory marker protein
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of OMP mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:161,851,499...161,852,049
|
|
| G
|
Orm1
|
orosomucoid 1
|
increases expression
|
EXP
|
Carmustine results in increased expression of ORM1 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:81,788,395...81,791,667
|
|
| G
|
P3h3
|
prolyl 3-hydroxylase 3
|
affects response to substance
|
ISO
|
P3H3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:159,332,514...159,348,428
Ensembl chr 4:159,332,434...159,348,004
|
|
| G
|
Paep
|
progestagen associated endometrial protein
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PAEP mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:28,929,252...28,932,592
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions increases cleavage
|
ISO
|
Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]
|
CTD |
PMID:24193513 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Pax8
|
paired box 8
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PAX8 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:27,584,002...27,640,631
|
|
| G
|
Pbx2
|
PBX homeobox 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PBX2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:4,156,107...4,161,503
Ensembl chr20:4,156,107...4,161,827
|
|
| G
|
Pcbd1
|
pterin-4 alpha-carbinolamine dehydratase 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PCBD1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:29,573,362...29,587,181
Ensembl chr20:29,573,423...29,587,180
|
|
| G
|
Pcdhb2
|
protocadherin beta 2
|
affects response to substance
|
ISO
|
PCDHB2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr18:29,280,004...29,282,790
Ensembl chr18:29,280,004...29,283,300
|
|
| G
|
Pcdhgc3
|
protocadherin gamma subfamily C, 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PCDHGC3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr18:29,884,245...29,919,095
|
|
| G
|
Pcolce
|
procollagen C-endopeptidase enhancer
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PCOLCE mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287
|
|
| G
|
Pcyt1a
|
phosphate cytidylyltransferase 1A, choline
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PCYT1A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr11:81,818,914...81,862,623
Ensembl chr11:81,819,285...81,862,395
|
|
| G
|
Pde5a
|
phosphodiesterase 5A
|
affects response to substance
|
ISO
|
PDE5A mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
increases expression
|
ISO
|
Carmustine results in increased expression of PDGFB protein
|
CTD |
PMID:15286697 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pfkfb2
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PFKFB2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971
|
|
| G
|
Pfkm
|
phosphofructokinase, muscle
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PFKM mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248
|
|
| G
|
Pfn1
|
profilin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PFN1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611
|
|
| G
|
Pgm2
|
phosphoglucomutase 2
|
affects response to substance
|
ISO
|
PGM2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr14:44,519,906...44,553,420
Ensembl chr14:44,519,906...44,553,770
|
|
| G
|
Phc2
|
polyhomeotic homolog 2
|
affects response to substance
|
ISO
|
PHC2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:146,285,000...146,383,664
Ensembl chr 5:146,285,008...146,383,663
|
|
| G
|
Phlda1
|
pleckstrin homology-like domain, family A, member 1
|
affects response to substance
|
ISO
|
PHLDA1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542
|
|
| G
|
Pik3c3
|
phosphatidylinositol 3-kinase, catalytic subunit type 3
|
affects response to substance
|
ISO
|
PIK3C3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539
|
|
| G
|
Pik3cd
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
|
affects response to substance
|
ISO
|
PIK3CD mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968
|
|
| G
|
Pik3r3
|
phosphoinositide-3-kinase regulatory subunit 3
|
increases expression
|
ISO
|
Carmustine results in increased expression of PIK3R3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762
|
|
| G
|
Pitpnc1
|
phosphatidylinositol transfer protein, cytoplasmic 1
|
affects response to substance
|
ISO
|
PITPNC1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344
|
|
| G
|
Pknox2
|
PBX/knotted 1 homeobox 2
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of PKNOX2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 8:44,789,464...45,051,933
Ensembl chr 8:44,789,467...44,979,754
|
|
| G
|
Pkp2
|
plakophilin 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of PKP2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr11:98,165,974...98,231,916
Ensembl chr11:98,165,974...98,231,916
|
|
| G
|
Pkp3
|
plakophilin 3
|
affects response to substance
|
ISO
|
PKP3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440
|
|
| G
|
Plekhg5
|
pleckstrin homology and RhoGEF domain containing G5
|
affects response to substance
|
ISO
|
PLEKHG5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229
|
|
| G
|
Pnpla2
|
patatin-like phospholipase domain containing 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of PNPLA2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359
|
|
| G
|
Polg2
|
DNA polymerase gamma 2, accessory subunit
|
affects response to substance
|
ISO
|
POLG2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:92,212,303...92,222,849
Ensembl chr10:92,212,304...92,222,726
|
|
| G
|
Polh
|
DNA polymerase eta
|
multiple interactions
|
ISO
|
[Carmustine co-treated with MDM4 protein] results in increased expression of POLH protein
|
CTD |
PMID:20472715 |
|
NCBI chr 9:22,275,929...22,310,576
Ensembl chr 9:22,275,946...22,310,577
|
|
| G
|
Polr2e
|
RNA polymerase II, I and III subunit E
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of POLR2E mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:10,317,332...10,321,280
Ensembl chr 7:10,317,389...10,321,276
|
|
| G
|
Popdc3
|
popeye domain cAMP effector 3
|
affects response to substance
|
ISO
|
POPDC3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr20:50,354,775...50,383,050
Ensembl chr20:50,354,767...50,385,674
|
|
| G
|
Ppm1g
|
protein phosphatase, Mg2+/Mn2+ dependent, 1G
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PPM1G mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:30,873,531...30,893,735
Ensembl chr 6:30,873,481...30,893,732
|
|
| G
|
Prc1
|
protein regulator of cytokinesis 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PRC1 mRNA
|
CTD |
PMID:17374387 |
|
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
|
|
| G
|
Prex1
|
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
|
affects response to substance
|
ISO
|
PREX1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764
|
|
| G
|
Prkaa2
|
protein kinase AMP-activated catalytic subunit alpha 2
|
affects response to substance
|
ISO
|
PRKAA2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
|
|
| G
|
Prl
|
prolactin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PRL mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
|
|
| G
|
Prm2
|
protamine 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PRM2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:5,383,208...5,383,949
Ensembl chr10:5,379,029...5,384,004
|
|
| G
|
Prph
|
peripherin
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of PRPH mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 7:132,096,888...132,101,070
Ensembl chr 7:132,097,285...132,101,068
|
|
| G
|
Prrx2
|
paired related homeobox 2
|
affects response to substance
|
ISO
|
PRRX2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:34,520,173...34,566,284
|
|
| G
|
Prss12
|
serine protease 12
|
affects response to substance
|
ISO
|
PRSS12 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941
|
|
| G
|
Pth2r
|
parathyroid hormone 2 receptor
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of PTH2R mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 9:74,199,785...74,304,326
Ensembl chr 9:74,199,785...74,304,326
|
|
| G
|
Ptpn3
|
protein tyrosine phosphatase, non-receptor type 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of PTPN3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:76,703,687...76,860,470
|
|
| G
|
Qpct
|
glutaminyl-peptide cyclotransferase
|
affects response to substance
|
ISO
|
QPCT mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:21,716,824...21,748,895
Ensembl chr 6:21,716,824...21,748,895
|
|
| G
|
Rab27b
|
RAB27B, member RAS oncogene family
|
affects response to substance
|
ISO
|
RAB27B mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr18:65,870,230...66,069,597
Ensembl chr18:65,876,342...66,067,700
|
|
| G
|
Rad23a
|
RAD23 homolog A, nucleotide excision repair protein
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RAD23A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543
|
|
| G
|
Rad51
|
RAD51 recombinase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RAD51 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
|
|
| G
|
Rad9a
|
RAD9 checkpoint clamp component A
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RAD9A mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161
|
|
| G
|
Rbm19
|
RNA binding motif protein 19
|
affects response to substance
|
ISO
|
RBM19 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:42,026,277...42,111,530
Ensembl chr12:42,026,278...42,111,530
|
|
| G
|
Rcn1
|
reticulocalbin 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RCN1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:112,295,838...112,310,082
Ensembl chr 3:112,295,838...112,310,082
|
|
| G
|
Rel
|
REL proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of REL protein]
|
CTD |
PMID:11970852 PMID:12433058 |
|
NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
ISO EXP
|
Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]; NFKBIA gene mutant form inhibits the reaction [Carmustine results in increased activity of [NFKB1 protein binds to RELA protein]] Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Carmustine inhibits the reaction [Lipopolysaccharides results in increased activity of [NFKB1 protein binds to RELA protein]] [Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]; diphenyleneiodonium inhibits the reaction [[Carmustine co-treated with Oligodeoxyribonucleotides analog] results in increased activity of [NFKB1 protein binds to RELA protein]]
|
CTD |
PMID:11970852 PMID:12433058 PMID:12477282 PMID:12675310 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Relb
|
RELB proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
Carmustine inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein]
|
CTD |
PMID:11970852 PMID:12433058 |
|
NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420
|
|
| G
|
Rfc3
|
replication factor C subunit 3
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of RFC3 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340
|
|
| G
|
Rgcc
|
regulator of cell cycle
|
affects response to substance
|
ISO
|
RGCC mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408
|
|
| G
|
Rgp1
|
RGP1 homolog, RAB6A GEF complex partner 1
|
affects response to substance
|
ISO
|
RGP1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:62,630,253...62,638,872
Ensembl chr 5:62,630,133...62,638,864
|
|
| G
|
Rgr
|
retinal G protein coupled receptor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RGR mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:12,821,858...12,836,665
Ensembl chr16:12,821,858...12,836,486
|
|
| G
|
Rhobtb3
|
Rho-related BTB domain containing 3
|
affects response to substance
|
ISO
|
RHOBTB3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906
|
|
| G
|
Rit2
|
Ras-like without CAAX 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of RIT2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr18:22,839,914...23,196,137
Ensembl chr18:22,839,915...23,269,823
|
|
| G
|
Rnase4
|
ribonuclease A family member 4
|
increases expression
|
ISO
|
Carmustine results in increased expression of RNASE4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639
|
|
| G
|
Rorb
|
RAR-related orphan receptor B
|
affects expression
|
EXP
|
Carmustine affects the expression of RORB mRNA
|
CTD |
PMID:19174181 |
|
NCBI chr 1:225,790,216...225,970,973
Ensembl chr 1:225,790,216...225,970,973
|
|
| G
|
S1pr3
|
sphingosine-1-phosphate receptor 3
|
affects response to substance
|
ISO
|
S1PR3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197
|
|
| G
|
Sat1
|
spermidine/spermine N1-acetyl transferase 1
|
affects response to substance
|
ISO
|
SAT1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr X:44,008,089...44,011,376
Ensembl chr X:44,006,781...44,011,374
|
|
| G
|
Scamp5
|
secretory carrier membrane protein 5
|
affects response to substance
|
ISO
|
SCAMP5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:66,739,794...66,778,538
Ensembl chr 8:66,741,940...66,751,099
|
|
| G
|
Scn1b
|
sodium voltage-gated channel beta subunit 1
|
increases expression
|
EXP
|
Carmustine results in increased expression of SCN1B mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:95,481,298...95,491,197
|
|
| G
|
Scn8a
|
sodium voltage-gated channel alpha subunit 8
|
affects response to substance
|
ISO
|
SCN8A mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:133,861,227...134,030,026
|
|
| G
|
Sdc1
|
syndecan 1
|
affects response to substance
|
ISO
|
SDC1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500
|
|
| G
|
Sema3a
|
semaphorin 3A
|
affects response to substance
|
ISO
|
SEMA3A mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:22,245,322...22,535,774
|
|
| G
|
Septin4
|
septin 4
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of SEPTIN4 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr10:72,863,969...72,888,018
Ensembl chr10:72,864,014...72,888,019
|
|
| G
|
Septin5
|
septin 5
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SEPTIN5 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr11:95,877,946...95,883,738
Ensembl chr11:95,873,864...95,883,737
|
|
| G
|
Serpinb1a
|
serpin family B member 1A
|
affects response to substance
|
ISO
|
SERPINB1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,799,415...31,808,166
|
|
| G
|
Sf1
|
splicing factor 1
|
affects response to substance
|
ISO
|
SF1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:213,099,260...213,113,590
|
|
| G
|
Sfpq
|
splicing factor proline and glutamine rich
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SFPQ mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926
|
|
| G
|
Sgca
|
sarcoglycan, alpha
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SGCA mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:80,397,158...80,416,165
Ensembl chr10:80,405,566...80,419,616
|
|
| G
|
Shmt2
|
serine hydroxymethyltransferase 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SHMT2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:65,244,247...65,249,580
Ensembl chr 7:65,244,247...65,249,567
|
|
| G
|
Shox1
|
SHOX homeobox 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SHOX mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:121,553,770...121,560,788
|
|
| G
|
Slc10a1
|
solute carrier family 10 member 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of SLC10A1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944
|
|
| G
|
Slc12a1
|
solute carrier family 12 member 1
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of SLC12A1 mRNA
|
CTD |
PMID:17727784 |
|
NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340
|
|
| G
|
Slc12a2
|
solute carrier family 12 member 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of SLC12A2 mRNA
|
CTD |
PMID:17727784 |
|
NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470
|
|
| G
|
Slc14a1
|
solute carrier family 14 member 1 (Kidd blood group)
|
affects response to substance
|
ISO
|
SLC14A1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489
|
|
| G
|
Slc15a2
|
solute carrier family 15 member 2
|
affects response to substance
|
ISO
|
SLC15A2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr11:77,519,565...77,548,609
Ensembl chr11:77,519,529...77,548,606
|
|
| G
|
Slc16a2
|
solute carrier family 16 member 2
|
increases expression
|
ISO
|
Carmustine results in increased expression of SLC16A2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:72,791,096...72,914,299
Ensembl chr X:72,781,876...72,914,498
|
|
| G
|
Slc19a2
|
solute carrier family 19 member 2
|
decreases expression
|
EXP
|
Carmustine results in decreased expression of SLC19A2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315
|
|
| G
|
Slc22a5
|
solute carrier family 22 member 5
|
affects response to substance
|
ISO
|
SLC22A5 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077
|
|
| G
|
Slc30a3
|
solute carrier family 30 member 3
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SLC30A3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:30,984,241...31,004,689
Ensembl chr 6:30,984,276...31,005,120
|
|
| G
|
Slc3a2
|
solute carrier family 3 member 2
|
increases expression
|
EXP
|
Carmustine results in increased expression of SLC3A2 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064
|
|
| G
|
Slc6a2
|
solute carrier family 6 member 2
|
increases expression
|
ISO
|
Carmustine results in increased expression of SLC6A2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348
|
|
| G
|
Slco1a4
|
solute carrier organic anion transporter family, member 1a4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SLCO1A2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816
|
|
| G
|
Slpi
|
secretory leukocyte peptidase inhibitor
|
affects response to substance
|
ISO
|
SLPI mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822
|
|
| G
|
Smarcd1
|
SWI/SNF related BAF chromatin remodeling complex subunit D1
|
increases expression
|
ISO
|
Carmustine results in increased expression of SMARCD1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:132,708,627...132,719,167
Ensembl chr 7:132,708,432...132,719,167
|
|
| G
|
Smpd2
|
sphingomyelin phosphodiesterase 2
|
increases expression
|
ISO
|
Carmustine results in increased expression of SMPD2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:46,568,627...46,571,741
Ensembl chr20:46,568,629...46,571,741
|
|
| G
|
Snapc1
|
small nuclear RNA activating complex, polypeptide 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of SNAPC1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 6:98,420,588...98,442,065
Ensembl chr 6:98,420,340...98,442,489
|
|
| G
|
Snapc3
|
small nuclear RNA activating complex, polypeptide 3
|
increases expression
|
ISO
|
Carmustine results in increased expression of SNAPC3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:102,863,867...102,890,573
Ensembl chr 5:102,863,854...102,893,499
|
|
| G
|
Sncg
|
synuclein, gamma
|
increases expression
|
ISO
|
Carmustine results in increased expression of SNCG mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:9,706,765...9,712,072
Ensembl chr16:9,706,753...9,712,076
|
|
| G
|
Snrpb2
|
small nuclear ribonucleoprotein polypeptide B2
|
increases expression
|
ISO
|
Carmustine results in increased expression of SNRPB2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:150,852,814...150,862,364
Ensembl chr 3:150,852,790...150,863,428
|
|
| G
|
Socs1
|
suppressor of cytokine signaling 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SOCS1 mRNA
|
CTD |
PMID:17374387 |
|
NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
decreases activity
|
ISO
|
Carmustine results in decreased activity of SOD1 protein
|
CTD |
PMID:19856331 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
affects response to substance increases response to substance multiple interactions decreases activity
|
ISO
|
SOD2 mRNA affects the susceptibility to Carmustine SOD2 protein results in increased susceptibility to Carmustine Pyruvates inhibits the reaction [SOD2 protein results in increased susceptibility to Carmustine] Carmustine results in decreased activity of SOD2 protein
|
CTD |
PMID:8877099 PMID:16365179 PMID:19856331 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Sorbs2
|
sorbin and SH3 domain containing 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SORBS2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986
|
|
| G
|
Sox9
|
SRY-box transcription factor 9
|
affects response to substance
|
ISO
|
SOX9 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250
|
|
| G
|
Sparc
|
secreted protein acidic and cysteine rich
|
affects response to substance
|
ISO
|
SPARC mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268
|
|
| G
|
Speg
|
striated muscle enriched protein kinase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SPEG mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 9:84,314,387...84,371,816
Ensembl chr 9:84,314,387...84,371,813
|
|
| G
|
Spen
|
spen family transcriptional repressor
|
affects response to substance
|
ISO
|
SPEN mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:159,058,258...159,131,789
Ensembl chr 5:159,058,258...159,165,934
|
|
| G
|
Sprr2b
|
small proline rich protein 2B
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SPRR2B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:180,548,428...180,548,700
|
|
| G
|
Sqle
|
squalene epoxidase
|
affects response to substance
|
ISO
|
SQLE mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050
|
|
| G
|
Srp14
|
signal recognition particle 14
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SRP14 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:125,896,128...125,899,819
Ensembl chr 3:125,896,556...125,899,819
|
|
| G
|
Sry
|
sex determining region Y
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of SRY mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr Y:465,260...465,772
Ensembl chr Y:465,260...465,772
|
|
| G
|
St3gal1
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
|
affects response to substance
|
ISO
|
ST3GAL1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242
|
|
| G
|
St6gal1
|
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of ST6GAL1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415
|
|
| G
|
St8sia1
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of ST8SIA1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:177,513,966...177,651,553
Ensembl chr 4:177,520,926...177,651,553
|
|
| G
|
Stam
|
signal transducing adaptor molecule
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of STAM mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr17:82,028,779...82,074,717
Ensembl chr17:82,028,703...82,075,013
|
|
| G
|
Stc1
|
stanniocalcin 1
|
affects response to substance
|
ISO
|
STC1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
|
|
| G
|
Stmn1
|
stathmin 1
|
affects response to substance
|
ISO
|
STMN1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:17440165 |
|
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
|
|
| G
|
Sts
|
steroid sulfatase
|
increases expression
|
ISO
|
Carmustine results in increased expression of STS mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr X:46,102,524...46,110,868
Ensembl chr X:46,102,548...46,111,104
|
|
| G
|
Stx1b
|
syntaxin 1B
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of STX1B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:191,846,016...191,864,878
Ensembl chr 1:191,833,743...191,871,633
|
|
| G
|
Stxbp2
|
syntaxin binding protein 2
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of STXBP2 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:6,487,265...6,498,351
Ensembl chr12:6,487,297...6,504,212
|
|
| G
|
Stxbp6
|
syntaxin binding protein 6
|
affects response to substance
|
ISO
|
STXBP6 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 6:67,647,721...67,884,369
Ensembl chr 6:67,650,556...67,884,725
|
|
| G
|
Synpo2
|
synaptopodin 2
|
affects response to substance
|
ISO
|
SYNPO2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:213,901,685...214,055,844
Ensembl chr 2:213,900,868...214,055,844
|
|
| G
|
Syp
|
synaptophysin
|
multiple interactions decreases expression
|
EXP
|
Melatonin inhibits the reaction [Carmustine results in decreased expression of SYP protein]
|
CTD |
PMID:17572393 |
|
NCBI chr X:17,521,348...17,536,449
Ensembl chr X:17,521,348...17,536,984
|
|
| G
|
Tac1
|
tachykinin, precursor 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TAC1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546
|
|
| G
|
Tagln
|
transgelin
|
affects response to substance
|
ISO
|
TAGLN mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563
|
|
| G
|
Tbx3
|
T-box transcription factor 3
|
affects response to substance
|
ISO
|
TBX3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:42,540,378...42,555,490
Ensembl chr12:42,540,378...42,554,171
|
|
| G
|
Tcf21
|
transcription factor 21
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TCF21 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:24,520,499...24,523,358
Ensembl chr 1:24,520,481...24,523,348
|
|
| G
|
Tcim
|
transcriptional and immune response regulator
|
increases response to substance
|
ISO
|
TCIM mRNA results in increased susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:74,298,344...74,299,637
Ensembl chr16:74,298,344...74,299,636
|
|
| G
|
Tdrp
|
testis development related protein
|
affects response to substance
|
ISO
|
TDRP mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:82,326,837...82,354,861
Ensembl chr16:82,314,220...82,354,861
|
|
| G
|
Tert
|
telomerase reverse transcriptase
|
decreases response to substance
|
ISO
|
TERT protein mutant form results in decreased susceptibility to Carmustine
|
CTD |
PMID:12488552 |
|
NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111
|
|
| G
|
Tfap2c
|
transcription factor AP-2 gamma
|
affects response to substance
|
ISO
|
TFAP2C mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:181,733,419...181,741,404
|
|
| G
|
Tfdp1
|
transcription factor Dp-1
|
affects response to substance
|
ISO
|
TFDP1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:82,864,220...82,903,166
Ensembl chr16:82,864,226...82,902,996
|
|
| G
|
Tfpi2
|
tissue factor pathway inhibitor 2
|
affects response to substance
|
ISO
|
TFPI2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426
|
|
| G
|
Tgfb1
|
transforming growth factor, beta 1
|
multiple interactions decreases expression
|
EXP
|
Melatonin inhibits the reaction [Carmustine results in decreased expression of TGFB1 protein]
|
CTD |
PMID:17572393 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
|
|
| G
|
Th
|
tyrosine hydroxylase
|
increases activity increases expression
|
EXP
|
Carmustine results in increased activity of TH protein Carmustine results in increased expression of TH mRNA; Carmustine results in increased expression of TH protein
|
CTD |
PMID:14670008 |
|
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
|
|
| G
|
Thbd
|
thrombomodulin
|
affects response to substance
|
ISO
|
THBD mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582
|
|
| G
|
Tle3
|
TLE family member 3, transcriptional corepressor
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TLE3 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 8:70,753,182...70,799,080
Ensembl chr 8:70,753,383...70,799,074
|
|
| G
|
Tmbim6
|
transmembrane BAX inhibitor motif containing 6
|
increases expression decreases expression
|
ISO
|
Carmustine results in increased expression of TMBIM6 mRNA Carmustine results in decreased expression of TMBIM6 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:132,386,134...132,422,492
|
|
| G
|
Tmem158
|
transmembrane protein 158
|
affects response to substance
|
ISO
|
TMEM158 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 8:131,791,137...131,792,135
Ensembl chr 8:131,787,277...131,796,882
|
|
| G
|
Tmem19
|
transmembrane protein 19
|
affects response to substance
|
ISO
|
TMEM19 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 7:52,844,985...52,871,708
Ensembl chr 7:52,844,985...52,872,012
|
|
| G
|
Tmprss15
|
transmembrane serine protease 15
|
affects response to substance
|
ISO
|
TMPRSS15 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr11:31,164,633...31,289,143
Ensembl chr11:31,164,633...31,288,953
|
|
| G
|
Tnc
|
tenascin C
|
affects response to substance
|
ISO
|
TNC mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions increases expression
|
EXP ISO
|
[Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]; Zinc Sulfate inhibits the reaction [Carmustine results in increased expression of TNF protein] Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of TNF protein]
|
CTD |
PMID:7532384 PMID:11970852 PMID:12433058 PMID:12477282 PMID:18528683 PMID:20046642 More...
|
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfaip3
|
TNF alpha induced protein 3
|
increases response to substance
|
ISO
|
TNFAIP3 mRNA results in increased susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979
|
|
| G
|
Tnfrsf11b
|
TNF receptor superfamily member 11B
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TNFRSF11B mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
|
|
| G
|
Tnfrsf19
|
TNF receptor superfamily member 19
|
affects response to substance
|
ISO
|
TNFRSF19 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr15:39,268,305...39,334,566
Ensembl chr15:39,268,305...39,356,438
|
|
| G
|
Tnfsf10
|
TNF superfamily member 10
|
affects response to substance
|
ISO
|
TNFSF10 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 2:112,136,550...112,155,903
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions increases expression increases response to substance decreases response to substance affects response to substance
|
ISO
|
[Carmustine co-treated with O(6)-benzylguanine] results in increased expression of TP53 protein; MDM4 protein promotes the reaction [Carmustine results in increased expression of TP53 protein] TP53 results in increased susceptibility to Carmustine TP53 protein results in decreased susceptibility to Carmustine TP53 protein modified form affects the susceptibility to Carmustine
|
CTD |
PMID:10455409 PMID:11861384 PMID:15735757 PMID:16193384 PMID:18632648 PMID:20472715 More...
|
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Tpd52l1
|
TPD52 like 1
|
affects response to substance
|
ISO
|
TPD52L1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:27,991,131...28,110,158
|
|
| G
|
Traf1
|
TNF receptor-associated factor 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TRAF1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264
|
|
| G
|
Trex1
|
three prime repair exonuclease 1
|
increases expression
|
ISO
|
Carmustine results in increased expression of TREX1 mRNA
|
CTD |
PMID:23578789 |
|
NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:118,585,081...118,586,083
|
|
| G
|
Trim50
|
tripartite motif-containing 50
|
affects response to substance
|
ISO
|
TRIM50 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:26,937,349...26,954,286
Ensembl chr12:26,937,349...26,954,270
|
|
| G
|
Tspan4
|
tetraspanin 4
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TSPAN4 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 1:206,001,731...206,021,414
Ensembl chr 1:206,001,731...206,021,413
|
|
| G
|
Tubb5
|
tubulin, beta 5 class I
|
increases expression
|
ISO
|
Carmustine results in increased expression of TUBB mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
|
|
| G
|
Tubg1
|
tubulin, gamma 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of TUBG1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr10:86,553,143...86,559,733
Ensembl chr10:86,552,499...86,559,730
|
|
| G
|
Tufm
|
Tu translation elongation factor, mitochondrial
|
affects response to substance
|
ISO
|
TUFM mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:190,504,373...190,507,980
Ensembl chr 1:190,504,373...190,508,952
|
|
| G
|
Tulp3
|
TUB like protein 3
|
affects response to substance
|
ISO
|
TULP3 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 4:163,276,583...163,318,297
Ensembl chr 4:163,276,583...163,318,390
|
|
| G
|
Txnrd1
|
thioredoxin reductase 1
|
multiple interactions decreases activity
|
EXP
|
[Carmustine co-treated with Buthionine Sulfoximine] results in decreased activity of TXNRD1 protein Carmustine results in decreased activity of TXNRD1 protein
|
CTD |
PMID:16085187 PMID:16288907 |
|
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
|
|
| G
|
Ugt8
|
UDP glycosyltransferase 8
|
increases expression
|
ISO
|
Carmustine results in increased expression of UGT8 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 2:216,938,884...217,007,167
Ensembl chr 2:216,938,990...217,007,167
|
|
| G
|
Upf1
|
UPF1, RNA helicase and ATPase
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of UPF1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr16:19,110,531...19,131,327
Ensembl chr16:19,110,538...19,131,327
|
|
| G
|
Vamp4
|
vesicle-associated membrane protein 4
|
affects response to substance
|
ISO
|
VAMP4 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr13:77,453,135...77,475,909
Ensembl chr13:77,453,121...77,476,024
|
|
| G
|
Vat1l
|
vesicle amine transport 1-like
|
affects response to substance
|
ISO
|
VAT1L mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:59,103,636...59,272,950
Ensembl chr19:59,103,636...59,272,950
|
|
| G
|
Vgf
|
VGF nerve growth factor inducible
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of VGF mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr12:25,274,004...25,281,803
Ensembl chr12:25,273,333...25,282,703
|
|
| G
|
Vldlr
|
very low density lipoprotein receptor
|
affects response to substance
|
ISO
|
VLDLR mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:234,239,769...234,272,150
Ensembl chr 1:234,240,121...234,272,154
|
|
| G
|
Wasf2
|
WASP family member 2
|
affects response to substance
|
ISO
|
WASF2 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:150,620,733...150,685,943
|
|
| G
|
Wfdc1
|
WAP four-disulfide core domain 1
|
affects response to substance
|
ISO
|
WFDC1 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr19:64,628,689...64,647,739
Ensembl chr19:64,607,794...64,648,028
|
|
| G
|
Wipf1
|
WAS/WASL interacting protein family, member 1
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of WIPF1 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 3:78,721,486...78,824,199
Ensembl chr 3:78,714,299...78,780,277
|
|
| G
|
Wnt5a
|
Wnt family member 5A
|
affects response to substance
|
ISO
|
WNT5A mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860
|
|
| G
|
Wt1
|
WT1 transcription factor
|
decreases response to substance
|
ISO
|
WT1 results in decreased susceptibility to Carmustine
|
CTD |
PMID:20820871 |
|
NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:112,021,641...112,068,444
|
|
| G
|
Ywhah
|
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of YWHAH mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr14:81,920,819...81,930,202
Ensembl chr14:81,920,590...81,947,930
|
|
| G
|
Zbtb17
|
zinc finger and BTB domain containing 17
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ZBTB17 mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 5:159,036,482...159,057,580
Ensembl chr 5:159,036,515...159,057,581
|
|
| G
|
Zc3h13
|
zinc finger CCCH type containing 13
|
affects response to substance
|
ISO
|
ZC3H13 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr15:57,016,686...57,081,201
Ensembl chr15:57,016,781...57,081,201
|
|
| G
|
Zfp112
|
zinc finger protein 112
|
affects response to substance
|
ISO
|
ZNF112 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr 1:88,804,833...88,819,889
Ensembl chr 1:88,813,821...88,819,761
|
|
| G
|
Zfp189
|
zinc finger protein 189
|
increases expression
|
EXP
|
Carmustine results in increased expression of ZNF189 mRNA
|
CTD |
PMID:16005536 |
|
NCBI chr 5:68,668,225...68,679,606
Ensembl chr 5:68,668,244...68,679,812
|
|
| G
|
Zfp655
|
zinc finger protein 655
|
affects response to substance
|
ISO
|
ZNF655 mRNA affects the susceptibility to Carmustine
|
CTD |
PMID:16365179 |
|
NCBI chr12:14,466,006...14,489,049
Ensembl chr12:14,471,415...14,488,678
|
|
| G
|
Zyx
|
zyxin
|
decreases expression
|
ISO
|
Carmustine results in decreased expression of ZYX mRNA
|
CTD |
PMID:15980968 |
|
NCBI chr 4:72,203,991...72,213,181
Ensembl chr 4:72,204,007...72,213,181
|
|
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression
|
ISO
|
fotemustine results in increased expression of CDKN1A mRNA
|
CTD |
PMID:25125662 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Fas
|
Fas cell surface death receptor
|
increases expression
|
ISO
|
fotemustine results in increased expression of FAS mRNA
|
CTD |
PMID:25125662 |
|
NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases expression
|
ISO
|
FOS mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA] fotemustine results in increased expression of FOS mRNA; fotemustine results in increased expression of FOS protein
|
CTD |
PMID:23578789 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
increases expression
|
ISO
|
fotemustine results in increased expression of GADD45A mRNA
|
CTD |
PMID:25125662 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases expression
|
ISO
|
fotemustine results in increased expression of H2AX protein modified form
|
CTD |
PMID:25125662 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hsf1
|
heat shock transcription factor 1
|
increases activity
|
ISO
|
fotemustine results in increased activity of HSF1 protein
|
CTD |
PMID:34170685 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions increases expression
|
ISO
|
fotemustine promotes the reaction [JUN protein binds to TREX1 promoter]; JUN mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA] fotemustine results in increased expression of JUN mRNA; fotemustine results in increased expression of JUN protein
|
CTD |
PMID:23578789 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases response to substance
|
ISO
|
MGMT protein results in decreased susceptibility to fotemustine
|
CTD |
PMID:12970393 PMID:16039682 PMID:20556481 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Polh
|
DNA polymerase eta
|
multiple interactions decreases response to substance increases expression
|
ISO
|
Dactinomycin inhibits the reaction [fotemustine results in increased expression of POLH mRNA]; fotemustine promotes the reaction [TP53 protein binds to POLH promoter]; pifithrin inhibits the reaction [fotemustine results in increased expression of POLH mRNA]; pifithrin inhibits the reaction [fotemustine results in increased expression of POLH protein] POLH protein results in decreased susceptibility to fotemustine fotemustine results in increased expression of POLH mRNA; fotemustine results in increased expression of POLH protein
|
CTD |
PMID:25125662 |
|
NCBI chr 9:22,275,929...22,310,576
Ensembl chr 9:22,275,946...22,310,577
|
|
| G
|
Tp53
|
tumor protein p53
|
multiple interactions increases expression
|
ISO
|
fotemustine promotes the reaction [TP53 protein binds to POLH promoter] fotemustine results in increased expression of TP53 protein; fotemustine results in increased expression of TP53 protein modified form
|
CTD |
PMID:25125662 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Trex1
|
three prime repair exonuclease 1
|
multiple interactions affects response to substance increases expression
|
ISO
|
FOS mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA]; fotemustine promotes the reaction [JUN protein binds to TREX1 promoter]; JUN mutant form inhibits the reaction [fotemustine results in increased expression of TREX1 mRNA] TREX1 affects the susceptibility to fotemustine fotemustine results in increased expression of TREX1 mRNA; fotemustine results in increased expression of TREX1 protein
|
CTD |
PMID:23578789 |
|
NCBI chr 8:118,585,082...118,586,382
Ensembl chr 8:118,585,081...118,586,083
|
|
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
increases expression
|
ISO
|
Lomustine results in increased expression of ABCB1 protein
|
CTD |
PMID:15239124 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Ace2
|
angiotensin converting enzyme 2
|
decreases expression
|
ISO
|
Lomustine results in decreased expression of ACE2 mRNA
|
CTD |
PMID:32808185 |
|
NCBI chr X:33,925,458...33,972,851
Ensembl chr X:33,925,458...33,971,596
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression
|
ISO
|
Lomustine results in increased expression of CDKN1A mRNA; Lomustine results in increased expression of CDKN1A protein
|
CTD |
PMID:24211769 PMID:27358234 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
increases expression
|
ISO
|
Lomustine results in increased expression of DDIT3 protein
|
CTD |
PMID:27358234 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
| G
|
Ina
|
internexin neuronal intermediate filament protein, alpha
|
multiple interactions
|
ISO
|
INA affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine]
|
CTD |
PMID:21246521 |
|
NCBI chr 1:255,838,129...255,849,680
Ensembl chr 1:255,838,129...255,849,680
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
multiple interactions decreases response to substance
|
ISO
|
MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] MGMT mRNA results in decreased susceptibility to Lomustine
|
CTD |
PMID:15448748 PMID:16033832 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Polh
|
DNA polymerase eta
|
increases expression multiple interactions decreases response to substance
|
ISO
|
Lomustine results in increased expression of POLH mRNA; Lomustine results in increased expression of POLH protein pifithrin inhibits the reaction [Lomustine results in increased expression of POLH protein] POLH protein results in decreased susceptibility to Lomustine
|
CTD |
PMID:25125662 |
|
NCBI chr 9:22,275,929...22,310,576
Ensembl chr 9:22,275,946...22,310,577
|
|
| G
|
Socs1
|
suppressor of cytokine signaling 1
|
decreases expression
|
ISO
|
Lomustine results in decreased expression of SOCS1 mRNA
|
CTD |
PMID:17374387 |
|
NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847
|
|
| G
|
Srxn1
|
sulfiredoxin 1
|
increases expression
|
ISO
|
Lomustine results in increased expression of SRXN1 protein
|
CTD |
PMID:27358234 |
|
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
|
|
| G
|
Stmn1
|
stathmin 1
|
affects response to substance
|
ISO
|
STMN1 mRNA affects the susceptibility to Lomustine
|
CTD |
PMID:17440165 |
|
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
|
|
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
increases expression
|
EXP
|
diisopropanolnitrosamine results in increased expression of ALDH1A1 protein
|
CTD |
PMID:33211169 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Cd44
|
CD44 molecule
|
increases expression
|
EXP
|
diisopropanolnitrosamine results in increased expression of CD44 protein
|
CTD |
PMID:33211169 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Cp
|
ceruloplasmin
|
multiple interactions
|
EXP
|
[diisopropanolnitrosamine co-treated with Propylthiouracil] results in increased expression of CP protein
|
CTD |
PMID:19497425 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein
|
CTD |
PMID:34186418 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA]; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [bisphenol A co-treated with diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of ESR1 protein; [bisphenol A co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein
|
CTD |
PMID:29050248 PMID:34186418 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases phosphorylation
|
EXP
|
diisopropanolnitrosamine results in increased phosphorylation of H2AX protein
|
CTD |
PMID:33211169 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hdac6
|
histone deacetylase 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein
|
CTD |
PMID:34186418 |
|
NCBI chr X:17,222,538...17,244,373
Ensembl chr X:17,222,856...17,244,370
|
|
| G
|
Ifng
|
interferon gamma
|
multiple interactions
|
EXP
|
2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein]; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein
|
CTD |
PMID:14736494 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il2
|
interleukin 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IL2 protein
|
CTD |
PMID:14736494 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Kras
|
KRAS proto-oncogene, GTPase
|
increases mutagenesis
|
EXP
|
diisopropanolnitrosamine results in increased mutagenesis of KRAS gene
|
CTD |
PMID:18271921 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
|
|
| G
|
Krt14
|
keratin 14
|
increases expression
|
EXP
|
diisopropanolnitrosamine results in increased expression of KRT14 protein
|
CTD |
PMID:33211169 |
|
NCBI chr10:85,638,182...85,642,450
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
multiple interactions
|
EXP
|
[diisopropanolnitrosamine co-treated with Propylthiouracil] results in increased expression of MKI67 protein; [Sulfadimethoxine co-treated with diisopropanolnitrosamine] results in increased expression of MKI67 protein; Copper deficiency inhibits the reaction [[diisopropanolnitrosamine co-treated with Propylthiouracil] results in increased expression of MKI67 protein]; Copper inhibits the reaction [[diisopropanolnitrosamine co-treated with Propylthiouracil] results in increased expression of MKI67 protein]; Indomethacin inhibits the reaction [[Sulfadimethoxine co-treated with diisopropanolnitrosamine] results in increased expression of MKI67 protein]; nimesulide inhibits the reaction [[Sulfadimethoxine co-treated with diisopropanolnitrosamine] results in increased expression of MKI67 protein]
|
CTD |
PMID:19497425 PMID:22387750 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein
|
CTD |
PMID:34186418 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions
|
EXP
|
[Potassium Iodide co-treated with diisopropanolnitrosamine] results in increased expression of PCNA protein
|
CTD |
PMID:29050248 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Tshb
|
thyroid stimulating hormone subunit beta
|
multiple interactions
|
EXP
|
[diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of TSHB protein
|
CTD |
PMID:29050248 |
|
NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:192,913,171...192,942,984
|
|
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
decreases expression
|
ISO EXP
|
4-nitrosodimethylaniline results in decreased expression of MGMT protein
|
CTD |
PMID:15542103 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of ALDH1A1 protein
|
CTD |
PMID:33211169 PMID:35771629 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
multiple interactions
|
EXP
|
[Butylhydroxybutylnitrosamine co-treated with Propolis analog] results in increased expression of BIRC5 mRNA
|
CTD |
PMID:26111810 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
|
Cat
|
catalase
|
increases activity
|
ISO
|
Butylhydroxybutylnitrosamine results in increased activity of CAT protein
|
CTD |
PMID:22095756 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions
|
EXP
|
[Butylhydroxybutylnitrosamine co-treated with Propolis analog] results in increased expression of CCND1 mRNA
|
CTD |
PMID:26111810 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Cd44
|
CD44 molecule
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of CD44 protein
|
CTD |
PMID:33211169 PMID:35771629 |
|
NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
|
|
| G
|
Chrna7
|
cholinergic receptor nicotinic alpha 7 subunit
|
multiple interactions
|
EXP
|
[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of CHRNA7 protein
|
CTD |
PMID:29501575 |
|
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
|
|
| G
|
Gstm1
|
glutathione S-transferase mu 1
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of GSTM1 protein
|
CTD |
PMID:24998975 |
|
NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
increases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in increased expression of GSTO1 protein
|
CTD |
PMID:24998975 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of H2AX protein
|
CTD |
PMID:26338220 PMID:35771629 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hgf
|
hepatocyte growth factor
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of HGF protein
|
CTD |
PMID:35771629 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
|
|
| G
|
Ifng
|
interferon gamma
|
multiple interactions
|
EXP
|
2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein]; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein
|
CTD |
PMID:14736494 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Il2
|
interleukin 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IL2 protein
|
CTD |
PMID:14736494 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Krt14
|
keratin 14
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of KRT14 protein
|
CTD |
PMID:33211169 |
|
NCBI chr10:85,638,182...85,642,450
|
|
| G
|
Krt15
|
keratin 15
|
increases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in increased expression of KRT15 protein
|
CTD |
PMID:24998975 |
|
NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142
|
|
| G
|
Krt18
|
keratin 18
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of KRT18 protein
|
CTD |
PMID:24998975 |
|
NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848 Ensembl chr10:135,035,982...135,039,848
|
|
| G
|
Krt8
|
keratin 8
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of KRT8 protein
|
CTD |
PMID:24998975 |
|
NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403
|
|
| G
|
Ldhb
|
lactate dehydrogenase B
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of LDHB protein
|
CTD |
PMID:24998975 |
|
NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
multiple interactions
|
EXP
|
[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of MKI67 protein; Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of MKI67 protein]; methyllycaconitine inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of MKI67 protein]
|
CTD |
PMID:29501575 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mt-co1
|
mitochondrially encoded cytochrome c oxidase I
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of COX1 protein
|
CTD |
PMID:22095756 |
|
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
multiple interactions increases expression
|
ISO EXP
|
Butylhydroxybutylnitrosamine results in increased expression of and results in increased localization of MYC protein; Niacinamide inhibits the reaction [Butylhydroxybutylnitrosamine results in increased expression of and results in increased localization of MYC protein] Butylhydroxybutylnitrosamine results in increased expression of MYC mRNA
|
CTD |
PMID:22028816 PMID:35771629 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Nqo1
|
NAD(P)H quinone dehydrogenase 1
|
decreases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of NQO1 protein
|
CTD |
PMID:24998975 |
|
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
|
|
| G
|
Numa1
|
nuclear mitotic apparatus protein 1
|
multiple interactions
|
EXP
|
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of NUMA1 protein]; [Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of NUMA1 protein; lupeol inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of NUMA1 protein]
|
CTD |
PMID:26251508 |
|
NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848
|
|
| G
|
Pmp22
|
peripheral myelin protein 22
|
multiple interactions
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of and results in decreased localization of PMP22 protein; Niacinamide inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of and results in decreased localization of PMP22 protein]
|
CTD |
PMID:22028816 |
|
NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940
|
|
| G
|
Pten
|
phosphatase and tensin homolog
|
multiple interactions
|
EXP
|
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in decreased expression of PTEN protein]; [Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in decreased expression of PTEN protein; lupeol inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in decreased expression of PTEN protein]
|
CTD |
PMID:26251508 |
|
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
multiple interactions
|
EXP
|
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of PTGS2 protein]; [Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of PTGS2 protein; lupeol inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of PTGS2 protein]
|
CTD |
PMID:26251508 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions
|
EXP
|
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased phosphorylation of RELA protein]; [Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased phosphorylation of RELA protein; lupeol inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased phosphorylation of RELA protein]
|
CTD |
PMID:26251508 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Sp1
|
Sp1 transcription factor
|
increases expression
|
ISO
|
Butylhydroxybutylnitrosamine results in increased expression of SP1 protein
|
CTD |
PMID:24998975 |
|
NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
multiple interactions increases expression
|
EXP
|
[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form; Hexamethonium inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form]; methyllycaconitine inhibits the reaction [[Nicotine co-treated with Butylhydroxybutylnitrosamine] results in increased expression of STAT3 protein modified form] Butylhydroxybutylnitrosamine results in increased expression of STAT3 mRNA
|
CTD |
PMID:29501575 PMID:35771629 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions
|
EXP
|
3,3'-diindolylmethane inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of TNF protein]; [Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of TNF protein; lupeol inhibits the reaction [[Butylhydroxybutylnitrosamine co-treated with Cacodylic Acid] results in increased expression of TNF protein]
|
CTD |
PMID:26251508 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Top2a
|
DNA topoisomerase II alpha
|
multiple interactions
|
EXP
|
[Butylhydroxybutylnitrosamine co-treated with Propolis analog] results in increased expression of TOP2A mRNA
|
CTD |
PMID:26111810 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
|
|
| G
|
Tp53
|
tumor protein p53
|
affects activity
|
ISO
|
TRP53 affects the activity of Butylhydroxybutylnitrosamine
|
CTD |
PMID:10395176 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Ugt1a1
|
UDP glucuronosyltransferase family 1 member A1
|
multiple interactions decreases expression
|
ISO
|
oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA]
|
CTD |
PMID:15374950 |
|
NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Ugt1a6a
|
UDP glucuronosyltransferase family 1 member A6a
|
decreases expression multiple interactions
|
ISO
|
Butylhydroxybutylnitrosamine results in decreased expression of UGT1A mRNA oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A mRNA]
|
CTD |
PMID:15374950 |
|
NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
|
|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
increases expression
|
EXP
|
Butylhydroxybutylnitrosamine results in increased expression of VEGFA protein
|
CTD |
PMID:24888239 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
|
|
|
|
| G
|
Gjb1
|
gap junction protein, beta 1
|
decreases expression
|
EXP
|
N-ethyl-N-hydroxyethylnitrosamine results in decreased expression of GJB1 mRNA
|
CTD |
PMID:2559087 |
|
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
|
|
|
|
| G
|
Aars1
|
alanyl-tRNA synthetase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AARS1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:55,906,694...55,930,499
Ensembl chr19:55,906,702...55,930,497
|
|
| G
|
Abcd1
|
ATP binding cassette subfamily D member 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ABCD1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr X:156,579,669...156,601,448
Ensembl chr X:156,579,785...156,601,446
|
|
| G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of ABCG5 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
|
|
| G
|
Acaca
|
acetyl-CoA carboxylase alpha
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ACACA intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
|
|
| G
|
Acadl
|
acyl-CoA dehydrogenase, long chain
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of ACADL mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
|
|
| G
|
Actn4
|
actinin alpha 4
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of ACTN4 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320
|
|
| G
|
Adam1a
|
ADAM metallopeptidase domain 1a
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ADAM1A mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:40,674,460...40,680,988
Ensembl chr12:40,676,918...40,684,619
|
|
| G
|
Adgrf4
|
adhesion G protein-coupled receptor F4
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of ADGRF4 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 9:25,769,265...25,800,438
Ensembl chr 9:25,769,265...25,800,438
|
|
| G
|
Adgrv1
|
adhesion G protein-coupled receptor V1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ADGRV1 gene
|
CTD |
PMID:17329413 |
|
NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372
|
|
| G
|
Adra2b
|
adrenoceptor alpha 2B
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of ADRA2B gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525
|
|
| G
|
Aen
|
apoptosis enhancing nuclease
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of AEN mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898
|
|
| G
|
Aff1
|
ALF transcription elongation factor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AFF1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr14:6,165,864...6,328,848
Ensembl chr14:6,169,562...6,328,879
|
|
| G
|
Agap1
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AGAP1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:97,487,382...97,922,870
Ensembl chr 9:97,487,406...97,922,870
|
|
| G
|
Aip
|
aryl-hydrocarbon receptor-interacting protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AIP gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:210,837,473...210,848,691
Ensembl chr 1:210,836,755...210,848,634
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
increases phosphorylation
|
ISO
|
Ethylnitrosourea results in increased phosphorylation of AKT1 protein
|
CTD |
PMID:32902906 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Aldh1l2
|
aldehyde dehydrogenase 1 family, member L2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ALDH1L2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:22,141,872...22,193,403
Ensembl chr 7:22,141,842...22,193,398
|
|
| G
|
Alg5
|
ALG5, dolichyl-phosphate beta-glucosyltransferase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ALG5 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 2:141,087,126...141,101,397
Ensembl chr 2:141,087,147...141,102,951
|
|
| G
|
Alk
|
ALK receptor tyrosine kinase
|
multiple interactions increases mutagenesis
|
ISO
|
[Ethylnitrosourea results in increased mutagenesis of ALK protein] inhibits the reaction [crizotinib results in decreased phosphorylation of ALK protein]; [Ethylnitrosourea results in increased mutagenesis of ALK protein] which results in decreased susceptibility to crizotinib; [Ethylnitrosourea results in increased mutagenesis of ALK protein] which results in decreased susceptibility to NVP-TAE684
|
CTD |
PMID:21948233 PMID:22034911 |
|
NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721
|
|
| G
|
Alms1
|
ALMS1, centrosome and basal body associated protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ALMS1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 4:119,683,085...119,783,471
Ensembl chr 4:119,683,076...119,783,471
|
|
| G
|
Ankrd11
|
ankyrin repeat domain containing 11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ANKRD11 gene
|
CTD |
PMID:17986521 |
|
NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491
|
|
| G
|
Ankrd35
|
ankyrin repeat domain 35
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ANKRD35 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 2:186,895,896...186,915,903
Ensembl chr 2:186,895,945...186,915,902
|
|
| G
|
Ankrd6
|
ankyrin repeat domain 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ANKRD6 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:51,999,225...52,139,623
Ensembl chr 5:51,999,221...52,139,594
|
|
| G
|
Antxr1
|
ANTXR cell adhesion molecule 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ANTXR1 intron
|
CTD |
PMID:16300676 |
|
NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
|
|
| G
|
Aoc3
|
amine oxidase, copper containing 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AOC3 intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:86,773,018...86,780,961
|
|
| G
|
Ap2a1
|
adaptor related protein complex 2 subunit alpha 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AP2A1 exon
|
CTD |
PMID:16300676 |
|
NCBI chr 1:104,520,789...104,550,655
Ensembl chr 1:104,520,792...104,550,655
|
|
| G
|
Ap2m1
|
adaptor related protein complex 2 subunit mu 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AP2M1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of APC gene
|
CTD |
PMID:16724327 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
Aplnr
|
apelin receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of APLNR 3' UTR
|
CTD |
PMID:27776689 |
|
NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:90,624,012...90,627,908
|
|
| G
|
Aqp2
|
aquaporin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of AQP2 exon
|
CTD |
PMID:16121255 |
|
NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319
|
|
| G
|
Arcn1
|
archain 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ARCN1 gene
|
CTD |
PMID:20502676 |
|
NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005
|
|
| G
|
Arl13b
|
ARF like GTPase 13B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ARL13B gene
|
CTD |
PMID:15755804 |
|
NCBI chr11:13,597,538...13,663,681
Ensembl chr11:13,597,538...13,663,546
|
|
| G
|
Asip
|
agouti signaling protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of A gene
|
CTD |
PMID:9475716 PMID:10517996 |
|
NCBI chr 3:163,933,768...164,021,377
Ensembl chr 3:164,015,903...164,021,378
|
|
| G
|
Atf7ip
|
activating transcription factor 7 interacting protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ATF7IP mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 4:171,117,122...171,202,871
Ensembl chr 4:171,117,122...171,202,867
|
|
| G
|
Atg12
|
autophagy related 12
|
multiple interactions decreases expression
|
ISO
|
Quercetin inhibits the reaction [Ethylnitrosourea results in decreased expression of ATG12 protein]
|
CTD |
PMID:32902906 |
|
NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261
|
|
| G
|
Atrx
|
ATRX, chromatin remodeler
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of ATRX gene
|
CTD |
PMID:16495775 |
|
NCBI chr X:74,916,548...75,062,880
Ensembl chr X:74,916,548...75,062,880
|
|
| G
|
Avpr1a
|
arginine vasopressin receptor 1A
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of AVPR1A gene
|
CTD |
PMID:16495775 |
|
NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BAD gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bahd1
|
bromo adjacent homology domain containing 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BAHD1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 3:126,341,853...126,368,281
Ensembl chr 3:126,345,371...126,368,278
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
increases expression affects expression
|
ISO EXP
|
Ethylnitrosourea results in increased expression of BAX mRNA Ethylnitrosourea affects the expression of BAX mRNA
|
CTD |
PMID:11356909 PMID:15954086 PMID:19100860 PMID:30944280 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
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| G
|
Bcap31
|
B-cell receptor-associated protein 31
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BCAP31 gene
|
CTD |
PMID:27776689 |
|
NCBI chr X:156,548,911...156,581,002
Ensembl chr X:156,548,911...156,579,371
|
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| G
|
Bcat2
|
branched chain amino acid transaminase 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BCAT2 gene
|
CTD |
PMID:14755340 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of BCL2 mRNA
|
CTD |
PMID:30944280 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l1
|
Bcl2-like 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of BCL2L1 mRNA
|
CTD |
PMID:30944280 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
| G
|
Bdnf
|
brain-derived neurotrophic factor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of BDNF gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
|
Becn1
|
beclin 1
|
decreases phosphorylation multiple interactions
|
ISO
|
Ethylnitrosourea results in decreased phosphorylation of BECN1 protein Quercetin inhibits the reaction [Ethylnitrosourea results in decreased phosphorylation of BECN1 protein]
|
CTD |
PMID:32902906 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
|
|
| G
|
Bmp5
|
bone morphogenetic protein 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BMP5 gene
|
CTD |
PMID:9475716 PMID:9825669 PMID:10517996 |
|
NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189
|
|
| G
|
Bop1
|
BOP1 ribosomal biogenesis factor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BOP1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529
|
|
| G
|
Brwd1
|
bromodomain and WD repeat domain containing 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of BRWD1 gene
|
CTD |
PMID:18353305 |
|
NCBI chr11:48,756,174...48,853,692
Ensembl chr11:48,756,811...48,848,256
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of BTG2 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
C3
|
complement C3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of C3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
|
|
| G
|
Cabcoco1
|
ciliary associated calcium binding coiled-coil 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CABCOCO1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr20:20,057,462...20,166,732
Ensembl chr20:20,057,517...20,167,174
|
|
| G
|
Cacna1a
|
calcium voltage-gated channel subunit alpha1 A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CACNA1A exon; Ethylnitrosourea results in increased mutagenesis of CACNA1A gene
|
CTD |
PMID:16724327 PMID:17376154 |
|
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599
|
|
| G
|
Cacna2d2
|
calcium voltage-gated channel auxiliary subunit alpha2delta 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CACNA2D2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759
|
|
| G
|
Capsl
|
calcyphosine-like
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CAPSL exon; Ethylnitrosourea results in increased mutagenesis of CAPSL intron
|
CTD |
PMID:16300676 |
|
NCBI chr 2:60,122,162...60,152,692
Ensembl chr 2:60,138,589...60,152,838
|
|
| G
|
Card11
|
caspase recruitment domain family, member 11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CARD11 gene
|
CTD |
PMID:16724327 |
|
NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045
|
|
| G
|
Casp3
|
caspase 3
|
increases cleavage
|
ISO
|
Ethylnitrosourea results in increased cleavage of CASP3 protein
|
CTD |
PMID:28549617 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Cckbr
|
cholecystokinin B receptor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of CCKBR gene
|
CTD |
PMID:16495775 |
|
NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745
|
|
| G
|
Ccnd1
|
cyclin D1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of CCND1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccne2
|
cyclin E2
|
multiple interactions decreases expression
|
ISO
|
DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CCNE2 mRNA]; Ethylnitrosourea affects the reaction [DICER1 protein affects the expression of CCNE2 mRNA]
|
CTD |
PMID:24478143 |
|
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
|
|
| G
|
Ccng1
|
cyclin G1
|
increases expression
|
ISO EXP
|
Ethylnitrosourea results in increased expression of CCNG1 mRNA
|
CTD |
PMID:15954086 PMID:19100860 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
|
|
| G
|
Cct8
|
chaperonin containing TCP1 subunit 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CCT8 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328
|
|
| G
|
Cd302
|
CD302 molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CD302 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737
|
|
| G
|
Cd36
|
CD36 molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CD36 gene
|
CTD |
PMID:15690042 PMID:16724327 |
|
NCBI chr 4:18,209,088...18,302,142
|
|
| G
|
Cd4
|
Cd4 molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CD4 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461
|
|
| G
|
Cd59b
|
CD59b molecule
|
increases mutagenesis decreases lipidation multiple interactions
|
ISO EXP
|
Ethylnitrosourea results in increased mutagenesis of CD59 protein Ethylnitrosourea results in decreased lipidation of CD59 protein [Ethylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [Ethylnitrosourea results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein
|
CTD |
PMID:17045307 PMID:19965957 PMID:20202993 PMID:27931811 |
|
NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310
|
|
| G
|
Cd83
|
CD83 molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CD83 gene
|
CTD |
PMID:16724327 |
|
NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047
|
|
| G
|
Cdan1
|
codanin 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CDAN1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:128,129,664...128,143,520
Ensembl chr 3:128,129,301...128,143,549
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression decreases expression multiple interactions
|
EXP ISO
|
Ethylnitrosourea results in increased expression of CDKN1A mRNA Ethylnitrosourea results in decreased expression of CDKN1A mRNA DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CDKN1A mRNA]
|
CTD |
PMID:15954086 PMID:19100860 PMID:24211769 PMID:24478143 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn2a
|
cyclin-dependent kinase inhibitor 2A
|
increases response to substance multiple interactions decreases expression
|
ISO
|
CDKN2A gene mutant form results in increased susceptibility to Ethylnitrosourea Phytic Acid inhibits the reaction [Ethylnitrosourea results in decreased expression of CDKN2A]
|
CTD |
PMID:17943659 PMID:21154115 |
|
NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
|
|
| G
|
Cdkn2c
|
cyclin-dependent kinase inhibitor 2C
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of CDKN2C protein
|
CTD |
PMID:28549617 |
|
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
|
|
| G
|
Celsr1
|
cadherin, EGF LAG seven-pass G-type receptor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CELSR1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856
|
|
| G
|
Cep104
|
centrosomal protein 104
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CEP104 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695
|
|
| G
|
Cep95
|
centrosomal protein 95
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CEP95 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:92,231,829...92,259,813
Ensembl chr10:92,231,512...92,259,810
|
|
| G
|
Chd9
|
chromodomain helicase DNA binding protein 9
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CHD9 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:32,114,379...32,337,488
Ensembl chr19:32,115,920...32,319,042
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of CHEK2 protein
|
CTD |
PMID:28549617 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Chgb
|
chromogranin B
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of CHGB mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054
|
|
| G
|
Chrm5
|
cholinergic receptor, muscarinic 5
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of CHRM5 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166
|
|
| G
|
Chrna6
|
cholinergic receptor nicotinic alpha 6 subunit
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of CHRNA6 gene
|
CTD |
PMID:16495775 |
|
NCBI chr16:71,400,615...71,407,315
Ensembl chr16:71,400,615...71,407,315
|
|
| G
|
Chrnd
|
cholinergic receptor nicotinic delta subunit
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of CHRND gene
|
CTD |
PMID:16495775 |
|
NCBI chr 9:95,310,316...95,318,734
Ensembl chr 9:95,310,298...95,318,745
|
|
| G
|
Chst14
|
carbohydrate sulfotransferase 14
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CHST14 intron; Ethylnitrosourea results in increased mutagenesis of CHST14 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:126,370,348...126,372,405
Ensembl chr 3:126,370,348...126,372,777
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of COL1A2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col4a1
|
collagen type IV alpha 1 chain
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of COL4A1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
|
|
| G
|
Col6a3
|
collagen type VI alpha 3 chain
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of COL6A3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990
|
|
| G
|
Commd4
|
COMM domain containing 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of COMMD4 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 8:66,462,188...66,465,700
Ensembl chr 8:66,462,188...66,465,756
|
|
| G
|
Cox11
|
cytochrome c oxidase copper chaperone COX11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of COX11 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,955,783...75,963,489
|
|
| G
|
Cpn1
|
carboxypeptidase N subunit 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CPN1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:252,793,786...252,822,675
Ensembl chr 1:252,793,423...252,822,664
|
|
| G
|
Cryaa
|
crystallin, alpha A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CRYAA gene
|
CTD |
PMID:16724327 |
|
NCBI chr20:9,784,872...9,788,656
Ensembl chr20:9,784,857...9,788,654
|
|
| G
|
Crybg2
|
crystallin beta-gamma domain containing 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CRYBG2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:151,570,540...151,602,163
|
|
| G
|
Crygb
|
crystallin, gamma B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CRYGB exon
|
CTD |
PMID:15878859 |
|
NCBI chr 9:73,955,204...73,957,264
Ensembl chr 9:73,955,204...73,957,264
|
|
| G
|
Ctnna1
|
catenin alpha 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CTNNA1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007
|
|
| G
|
Ctrl
|
chymotrypsin-like
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CTRB1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr19:50,737,078...50,740,659
Ensembl chr19:50,737,079...50,738,979
|
|
| G
|
Cux2
|
cut-like homeobox 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CUX2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CYP17A1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Cyp46a1
|
cytochrome P450, family 46, subfamily a, polypeptide 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of CYP46A1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971
|
|
| G
|
Cysltr2
|
cysteinyl leukotriene receptor 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of CYSLTR2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr15:54,599,043...54,638,314
Ensembl chr15:54,598,818...54,713,597
|
|
| G
|
Dalrd3
|
DALR anticodon binding domain containing 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DALRD3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 8:118,142,009...118,147,082
Ensembl chr 8:118,144,197...118,147,822
|
|
| G
|
Dbh
|
dopamine beta-hydroxylase
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of DBH gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316
|
|
| G
|
Dcbld2
|
discoidin, CUB and LCCL domain containing 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of DCBLD2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr11:55,594,691...55,649,113
Ensembl chr11:55,594,691...55,649,085
|
|
| G
|
Dchs1
|
dachsous cadherin-related 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DCHS1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:169,516,758...169,550,789
Ensembl chr 1:169,516,762...169,536,639
|
|
| G
|
Dclre1b
|
DNA cross-link repair 1B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DCLRE1B mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:193,998,350...194,006,873
Ensembl chr 2:193,998,354...194,006,864
|
|
| G
|
Dcp1b
|
decapping mRNA 1B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DCP1B mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 4:154,030,181...154,068,038
Ensembl chr 4:154,030,690...154,068,035
|
|
| G
|
Ddx5
|
DEAD-box helicase 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DDX5 gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:92,224,393...92,231,928
Ensembl chr10:92,224,395...92,231,300
|
|
| G
|
Depdc1b
|
DEP domain containing 1B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DEPDC1B intron
|
CTD |
PMID:27776689 |
|
NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202
|
|
| G
|
Derl3
|
derlin 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DERL3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477
|
|
| G
|
Dffb
|
DNA fragmentation factor subunit beta
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DFFB intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225
|
|
| G
|
Dhx37
|
DEAH-box helicase 37
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DHX37 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240
|
|
| G
|
Dhx38
|
DEAH-box helicase 38
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DHX38 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:54,422,418...54,439,434
Ensembl chr19:54,422,418...54,439,423
|
|
| G
|
Dicer1
|
dicer 1 ribonuclease III
|
multiple interactions
|
ISO
|
DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CCNE2 mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CDKN1A mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of GADD45B mRNA]; DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of JUN mRNA]; Ethylnitrosourea affects the reaction [DICER1 protein affects the expression of CCNE2 mRNA]
|
CTD |
PMID:24478143 |
|
NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:129,396,014...129,457,252
|
|
| G
|
Dip2a
|
disco-interacting protein 2 homolog A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DIP2A intron
|
CTD |
PMID:27776689 |
|
NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,038...12,370,532
|
|
| G
|
Disp1
|
dispatched RND transporter family member 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DISP1 gene
|
CTD |
PMID:15755804 PMID:16724327 |
|
NCBI chr13:97,252,574...97,398,329
Ensembl chr13:97,252,574...97,398,460
|
|
| G
|
Dmd
|
dystrophin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DMD gene
|
CTD |
PMID:16724327 |
|
NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835
|
|
| G
|
Dnah5
|
dynein, axonemal, heavy chain 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DNAH5 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914
|
|
| G
|
Dnajc2
|
DnaJ heat shock protein family (Hsp40) member C2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DNAJC2 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 4:14,162,490...14,189,662
Ensembl chr 4:14,163,838...14,192,846
|
|
| G
|
Dnm3
|
dynamin 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DNM3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of DNMT1
|
CTD |
PMID:21154115 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Drd1
|
dopamine receptor D1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of DRD1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166
|
|
| G
|
Dscam
|
DS cell adhesion molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DSCAM mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:49,391,385...49,976,861
Ensembl chr11:49,347,531...49,976,238
|
|
| G
|
Dst
|
dystonin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DST gene
|
CTD |
PMID:16724327 |
|
NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533
|
|
| G
|
Dtx3l
|
deltex E3 ubiquitin ligase 3L
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DTX3L mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:78,320,225...78,329,837
Ensembl chr11:78,317,650...78,329,837
|
|
| G
|
Dvl3
|
dishevelled segment polarity protein 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DVL3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:93,869,834...93,887,013
Ensembl chr11:93,869,834...93,886,903
|
|
| G
|
Dync1h1
|
dynein cytoplasmic 1 heavy chain 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DYNC1H1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116
|
|
| G
|
Dync2h1
|
dynein cytoplasmic 2 heavy chain 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of DYNC2H1 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 8:12,473,955...12,697,075
Ensembl chr 8:12,473,955...12,697,058
|
|
| G
|
Edn3
|
endothelin 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EDN3 exon
|
CTD |
PMID:17516928 |
|
NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329
|
|
| G
|
Ednrb
|
endothelin receptor type B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EDNRB gene
|
CTD |
PMID:9475716 PMID:17174358 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EGFR gene
|
CTD |
PMID:15366372 PMID:16724327 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Eif3j
|
eukaryotic translation initiation factor 3, subunit J
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EIF3J gene
|
CTD |
PMID:27776689 |
|
NCBI chr 3:129,438,715...129,460,953
Ensembl chr 3:129,438,722...129,462,246
|
|
| G
|
Emx2
|
empty spiracles homeobox 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EMX2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671
|
|
| G
|
Enam
|
enamelin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ENAM exon; Ethylnitrosourea results in increased mutagenesis of ENAM intron
|
CTD |
PMID:15649948 PMID:17652207 |
|
NCBI chr14:19,840,773...19,865,476
Ensembl chr14:19,840,773...19,865,468
|
|
| G
|
Epb41l5
|
erythrocyte membrane protein band 4.1 like 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EPB41L5 gene
|
CTD |
PMID:15755804 |
|
NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of EPHX1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of ERBB2 gene
|
CTD |
PMID:16651423 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
|
|
| G
|
Exosc5
|
exosome component 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of EXOSC5 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046
|
|
| G
|
Fah
|
fumarylacetoacetate hydrolase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FAH gene
|
CTD |
PMID:16180137 PMID:16724327 |
|
NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046
|
|
| G
|
Fam216a
|
family with sequence similarity 216, member A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FAM216A gene
|
CTD |
PMID:27776689 |
|
NCBI chr12:39,859,307...39,868,450
Ensembl chr12:39,859,172...39,868,442
|
|
| G
|
Fam98a
|
family with sequence similarity 98, member A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FAM98A mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 6:25,626,108...25,640,767
Ensembl chr 6:25,625,984...25,640,767
|
|
| G
|
Fancc
|
FA complementation group C
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FANCC mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096
|
|
| G
|
Fat2
|
FAT atypical cadherin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FAT2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:39,864,765...39,957,027
Ensembl chr10:39,864,766...39,956,902
|
|
| G
|
Fdft1
|
farnesyl diphosphate farnesyl transferase 1
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of FDFT1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168
|
|
| G
|
Fech
|
ferrochelatase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FECH gene
|
CTD |
PMID:16724327 |
|
NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546
|
|
| G
|
Fmn2
|
formin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FMN2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of FOS mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
|
|
| G
|
Foxf2
|
forkhead box F2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FOXF2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr17:33,044,446...33,051,259
Ensembl chr17:32,846,603...33,051,259
|
|
| G
|
Foxn1
|
forkhead box N1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FOXN1 gene
|
CTD |
PMID:16972005 |
|
NCBI chr10:63,749,461...63,778,468
Ensembl chr10:63,749,461...63,771,771
|
|
| G
|
Foxo1
|
forkhead box O1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of FOXO1 protein
|
CTD |
PMID:32902906 |
|
NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419
|
|
| G
|
Frem1
|
Fras1 related extracellular matrix 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FREM1 gene
|
CTD |
PMID:23221805 |
|
NCBI chr 5:102,367,201...102,515,464
Ensembl chr 5:102,367,201...102,515,404
|
|
| G
|
Fryl
|
FRY like transcription coactivator
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of FRYL mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr14:35,307,225...35,545,199
Ensembl chr14:35,310,656...35,545,147
|
|
| G
|
Fshr
|
follicle stimulating hormone receptor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of FSHR gene
|
CTD |
PMID:16495775 |
|
NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288
|
|
| G
|
Gadd45b
|
growth arrest and DNA-damage-inducible, beta
|
increases expression decreases expression multiple interactions
|
ISO
|
Ethylnitrosourea results in increased expression of GADD45B mRNA Ethylnitrosourea results in decreased expression of GADD45B mRNA DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of GADD45B mRNA]
|
CTD |
PMID:19100860 PMID:24478143 |
|
NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718
|
|
| G
|
Gal3st3
|
galactose-3-O-sulfotransferase 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GAL3ST3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:212,022,989...212,032,802
Ensembl chr 1:212,023,000...212,032,801
|
|
| G
|
Gata1
|
GATA binding protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GATA1 gene
|
CTD |
PMID:16966598 |
|
NCBI chr X:17,193,291...17,209,462
Ensembl chr X:17,201,633...17,209,459
|
|
| G
|
Gata6
|
GATA binding protein 6
|
multiple interactions increases activity
|
ISO
|
Ethylnitrosourea promotes the reaction [GATA6 protein binds to KRAS exon] Ethylnitrosourea results in increased activity of GATA6 protein
|
CTD |
PMID:16271038 |
|
NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322
|
|
| G
|
Gck
|
glucokinase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GCK exon; Ethylnitrosourea results in increased mutagenesis of GCK gene
|
CTD |
PMID:15102714 PMID:15161764 PMID:16724327 PMID:18056790 |
|
NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949
|
|
| G
|
Gcm2
|
glial cells missing transcription factor 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GCM2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr17:23,858,379...23,867,495
Ensembl chr17:23,858,379...23,867,495
|
|
| G
|
Gdf15
|
growth differentiation factor 15
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of GDF15 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gfi1
|
growth factor independent 1 transcriptional repressor
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of GFI1 protein
|
CTD |
PMID:28549617 |
|
NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730
|
|
| G
|
Ggt1
|
gamma-glutamyltransferase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GGT1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GJA1 exon; Ethylnitrosourea results in increased mutagenesis of GJA1 gene
|
CTD |
PMID:15548583 PMID:16155213 PMID:16724327 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Gja8
|
gap junction protein, alpha 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GJA8 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 2:187,179,668...187,181,284
Ensembl chr 2:187,175,507...187,186,167
|
|
| G
|
Gjb1
|
gap junction protein, beta 1
|
multiple interactions
|
EXP
|
[Ethylnitrosourea co-treated with chlorendic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with ciprofibrate] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Dioxins] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Phenobarbital] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with pirinixic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Tamoxifen] results in decreased expression of GJB1 protein
|
CTD |
PMID:1973356 |
|
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
|
|
| G
|
Gjb2
|
gap junction protein, beta 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GJB2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
|
|
| G
|
Gli1
|
GLI family zinc finger 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GLI1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
| G
|
Gli3
|
GLI family zinc finger 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GLI3 gene
|
CTD |
PMID:18397875 |
|
NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198
|
|
| G
|
Glra1
|
glycine receptor, alpha 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GLRA1 exon
|
CTD |
PMID:16964444 |
|
NCBI chr10:40,128,284...40,228,612
Ensembl chr10:40,130,121...40,227,815
|
|
| G
|
Gna11
|
G protein subunit alpha 11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GNA11 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,814,327...8,830,558
|
|
| G
|
Gnaq
|
G protein subunit alpha q
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GNAQ gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:222,852,097...223,126,742
|
|
| G
|
Gnas
|
GNAS complex locus
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GNAS gene
|
CTD |
PMID:16724327 |
|
NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536
|
|
| G
|
Gnptg
|
N-acetylglucosamine-1-phosphate transferase subunit gamma
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GNPTG intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:14,756,685...14,761,636
|
|
| G
|
Gnrhr
|
gonadotropin releasing hormone receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GNRHR gene
|
CTD |
PMID:15625238 |
|
NCBI chr14:22,211,666...22,229,654
|
|
| G
|
Gpatch2
|
G patch domain containing 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GPATCH2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:101,316,413...101,457,109
Ensembl chr13:101,316,413...101,457,109
|
|
| G
|
Gpkow
|
G patch domain and KOW motifs
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GPKOW mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr X:17,463,521...17,478,298
Ensembl chr X:17,463,525...17,478,298
|
|
| G
|
Gpr137
|
G protein-coupled receptor 137
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GPR137 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:213,558,846...213,562,422
Ensembl chr 1:213,558,846...213,563,966
|
|
| G
|
Gpr153
|
G protein-coupled receptor 153
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GPR153 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 5:168,064,134...168,075,697
Ensembl chr 5:168,064,311...168,074,532
|
|
| G
|
Gpr33-ps1
|
G protein-coupled receptor 33, pseudogene 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GPR33 gene
|
CTD |
PMID:16720677 |
|
NCBI chr 6:75,209,776...75,210,781
Ensembl chr 6:75,209,776...75,210,781
|
|
| G
|
Grid2
|
glutamate ionotropic receptor delta type subunit 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GRID2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 4:93,745,165...95,222,354
Ensembl chr 4:93,745,277...95,219,868
|
|
| G
|
Grik1
|
glutamate ionotropic receptor kainate type subunit 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of GRIK1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr11:40,655,974...41,056,966
Ensembl chr11:40,655,975...41,056,517
|
|
| G
|
Grm6
|
glutamate metabotropic receptor 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GRM6 exon
|
CTD |
PMID:17430614 |
|
NCBI chr10:35,669,003...35,683,729
Ensembl chr10:35,669,003...35,683,729
|
|
| G
|
Grm8
|
glutamate metabotropic receptor 8
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of GRM8 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:56,770,771...57,687,639
|
|
| G
|
Grpr
|
gastrin releasing peptide receptor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of GRPR gene
|
CTD |
PMID:16495775 |
|
NCBI chr X:34,630,238...34,670,245
Ensembl chr X:34,630,229...34,670,245
|
|
| G
|
Gsdme
|
gasdermin E
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of GSDME mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
|
|
| G
|
Gsk3b
|
glycogen synthase kinase 3 beta
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of GSK3B protein
|
CTD |
PMID:28549617 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
|
|
| G
|
Gstt1
|
glutathione S-transferase theta 1
|
affects response to substance
|
ISO
|
GSTT1 gene polymorphism affects the susceptibility to Ethylnitrosourea
|
CTD |
PMID:17158087 |
|
NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases phosphorylation
|
ISO
|
Ethylnitrosourea results in increased phosphorylation of H2AX protein
|
CTD |
PMID:34510228 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
| G
|
Hadhb
|
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HADHB exon
|
CTD |
PMID:17116638 |
|
NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835
|
|
| G
|
Hdac1
|
histone deacetylase 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of HDAC1
|
CTD |
PMID:21154115 |
|
NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387
|
|
| G
|
Hectd1
|
HECT domain E3 ubiquitin protein ligase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HECTD1 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 6:74,916,803...75,003,408
Ensembl chr 6:74,916,803...75,003,408
|
|
| G
|
Hes3
|
hes family bHLH transcription factor 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HES3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:168,076,337...168,082,270
Ensembl chr 5:168,077,093...168,078,987
|
|
| G
|
Hfe
|
homeostatic iron regulator
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HFE mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208
|
|
| G
|
Hikeshi
|
heat shock protein nuclear import factor hikeshi
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HIKESHI gene
|
CTD |
PMID:16157679 |
|
NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911
|
|
| G
|
Hmcn2
|
hemicentin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HMCN2 3' UTR; Ethylnitrosourea results in increased mutagenesis of HMCN2 intron; Ethylnitrosourea results in increased mutagenesis of HMCN2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:34,986,246...35,136,047
Ensembl chr 3:34,986,263...35,136,106
|
|
| G
|
Hmgcs1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of HMGCS1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of HMOX1 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
|
|
| G
|
Hoxd12
|
homeo box D12
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HOXD12 gene
|
CTD |
PMID:19108020 |
|
NCBI chr 3:79,985,106...79,986,227
Ensembl chr 3:79,985,106...79,986,227
|
|
| G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
increases mutagenesis
|
EXP ISO
|
Ethylnitrosourea results in increased mutagenesis of HPRT1 gene
|
CTD |
PMID:22167886 PMID:32529823 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Hr
|
HR, lysine demethylase and nuclear receptor corepressor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HR exon; Ethylnitrosourea results in increased mutagenesis of HR gene
|
CTD |
PMID:16455232 PMID:16461637 PMID:16724327 |
|
NCBI chr15:52,036,540...52,056,019
Ensembl chr15:52,036,540...52,056,015
|
|
| G
|
Hras
|
HRas proto-oncogene, GTPase
|
increases response to substance
|
ISO
|
HRAS protein results in increased susceptibility to Ethylnitrosourea
|
CTD |
PMID:11182032 PMID:26558449 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
|
|
| G
|
Hrc
|
histidine rich calcium binding protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HRC mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:104,949,750...104,953,475
Ensembl chr 1:104,949,741...104,954,193
|
|
| G
|
Hsf1
|
heat shock transcription factor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of HSF1 3' UTR
|
CTD |
PMID:27776689 |
|
NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665
|
|
| G
|
Hsp90ab1
|
heat shock protein 90 alpha family class B member 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of HSP90AB1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
|
|
| G
|
Htt
|
huntingtin
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of HTT gene
|
CTD |
PMID:16495775 |
|
NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668
|
|
| G
|
Id1
|
inhibitor of DNA binding 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of ID1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
|
|
| G
|
Id3
|
inhibitor of DNA binding 3
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of ID3 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
|
|
| G
|
Ifi35
|
interferon-induced protein 35
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IFI35 gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
|
|
| G
|
Ift172
|
intraflagellar transport 172
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IFT172 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 6:30,801,841...30,841,239
Ensembl chr 6:30,801,918...30,840,830
|
|
| G
|
Ift88
|
intraflagellar transport 88
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IFT88 gene
|
CTD |
PMID:15755804 PMID:16724327 |
|
NCBI chr15:35,685,678...35,786,875
Ensembl chr15:35,688,927...35,781,634
|
|
| G
|
Igf1r
|
insulin-like growth factor 1 receptor
|
increases mutagenesis increases phosphorylation
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IGF1R gene Ethylnitrosourea results in increased phosphorylation of IGF1R protein
|
CTD |
PMID:16461637 PMID:32902906 |
|
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
|
|
| G
|
Ikzf1
|
IKAROS family zinc finger 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IKZF1 gene
|
CTD |
PMID:15790496 |
|
NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574
|
|
| G
|
Il7
|
interleukin 7
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IL7 exon
|
CTD |
PMID:17151827 PMID:17179092 |
|
NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389
|
|
| G
|
Ina
|
internexin neuronal intermediate filament protein, alpha
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of INA mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 1:255,838,129...255,849,680
Ensembl chr 1:255,838,129...255,849,680
|
|
| G
|
Inpp5d
|
inositol polyphosphate-5-phosphatase D
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of INPP5D protein
|
CTD |
PMID:32902906 |
|
NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
|
|
| G
|
Ins2
|
insulin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of INS2 gene
|
CTD |
PMID:18056790 |
|
NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
|
|
| G
|
Insig1
|
insulin induced gene 1
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of INSIG1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778
|
|
| G
|
Insr
|
insulin receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of INSR gene
|
CTD |
PMID:18056790 |
|
NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
|
|
| G
|
Iqck
|
IQ motif containing K
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IQCK mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:182,630,678...182,748,325
Ensembl chr 1:182,630,673...182,748,325
|
|
| G
|
Irx6
|
iroquois homeobox 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of IRX6 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:30,503,416...30,509,396
Ensembl chr19:30,503,419...30,509,382
|
|
| G
|
Itpkb
|
inositol-trisphosphate 3-kinase B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ITPKB gene
|
CTD |
PMID:16724327 |
|
NCBI chr13:94,601,072...94,696,180
Ensembl chr13:94,601,167...94,696,179
|
|
| G
|
Jag1
|
jagged canonical Notch ligand 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of JAG1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872
|
|
| G
|
Jak1
|
Janus kinase 1
|
increases phosphorylation
|
ISO
|
Ethylnitrosourea results in increased phosphorylation of JAK1 protein
|
CTD |
PMID:27725143 |
|
NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
|
|
| G
|
Jak3
|
Janus kinase 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of JAK3 gene
|
CTD |
PMID:16724327 |
|
NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222
|
|
| G
|
Jchain
|
joining chain of multimeric IgA and IgM
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of JCHAIN gene
|
CTD |
PMID:15175647 |
|
NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,822,976...19,838,307
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression decreases expression multiple interactions
|
ISO
|
Ethylnitrosourea results in increased expression of JUN mRNA Ethylnitrosourea results in decreased expression of JUN mRNA DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of JUN mRNA]
|
CTD |
PMID:19100860 PMID:24478143 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Kcna2
|
potassium voltage-gated channel subfamily A member 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNA2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:197,392,746...197,406,606
Ensembl chr 2:197,392,698...197,407,519
|
|
| G
|
Kcne1
|
potassium voltage-gated channel subfamily E regulatory subunit 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNE1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr11:45,066,875...45,080,024
Ensembl chr11:45,064,162...45,081,247
|
|
| G
|
Kcnh3
|
potassium voltage-gated channel subfamily H member 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNH3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 7:132,244,492...132,262,725
Ensembl chr 7:132,244,880...132,262,721
|
|
| G
|
Kcnj11
|
potassium inwardly-rectifying channel, subfamily J, member 11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNJ11 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169
|
|
| G
|
Kcnj8
|
potassium inwardly-rectifying channel, subfamily J, member 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNJ8 gene
|
CTD |
PMID:18026101 |
|
NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531
|
|
| G
|
Kcnk4
|
potassium two pore domain channel subfamily K member 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNK4 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:213,547,577...213,558,706
Ensembl chr 1:213,547,577...213,555,861
|
|
| G
|
Kcnq1
|
potassium voltage-gated channel subfamily Q member 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNQ1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:207,721,131...208,054,072
|
|
| G
|
Kcnq2
|
potassium voltage-gated channel subfamily Q member 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KCNQ2 exon
|
CTD |
PMID:16464983 |
|
NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:188,572,926...188,631,302
|
|
| G
|
Kdr
|
kinase insert domain receptor
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of KDR protein
|
CTD |
PMID:28549617 |
|
NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
|
|
| G
|
Kif3a
|
kinesin family member 3a
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KIF3A gene
|
CTD |
PMID:15755804 PMID:16724327 |
|
NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516
|
|
| G
|
Kiss1r
|
KISS1 receptor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of KISS1R gene
|
CTD |
PMID:16495775 |
|
NCBI chr 7:10,435,766...10,439,424
Ensembl chr 7:10,435,766...10,439,424
|
|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KIT exon; Ethylnitrosourea results in increased mutagenesis of KIT gene
|
CTD |
PMID:15731517 PMID:15820307 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
|
|
| G
|
Klk8
|
kallikrein related-peptidase 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KLK8 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:103,388,352...103,395,195
Ensembl chr 1:103,388,352...103,395,195
|
|
| G
|
Kmt2b
|
lysine methyltransferase 2B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KMT2B gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:94,949,144...94,969,239
Ensembl chr 1:94,949,144...94,968,441
|
|
| G
|
Kras
|
KRAS proto-oncogene, GTPase
|
multiple interactions increases mutagenesis
|
ISO
|
Ethylnitrosourea promotes the reaction [GATA6 protein binds to KRAS exon]; Ethylnitrosourea promotes the reaction [NFYA protein binds to KRAS exon] Ethylnitrosourea results in increased mutagenesis of KRAS gene
|
CTD |
PMID:15790496 PMID:16271038 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
|
|
| G
|
Krt35
|
keratin 35
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KRT35 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:85,526,571...85,529,968
Ensembl chr10:85,526,571...85,529,968
|
|
| G
|
Krt71
|
keratin 71
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of KRT71 gene
|
CTD |
PMID:17143583 |
|
NCBI chr 7:134,752,240...134,778,765
Ensembl chr 7:134,752,248...134,761,033
|
|
| G
|
Lama2
|
laminin subunit alpha 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LAMA2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:19,492,126...20,140,056
Ensembl chr 1:19,244,599...20,140,056
|
|
| G
|
Lamb3
|
laminin subunit beta 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LAMB3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
|
|
| G
|
Lamc2
|
laminin subunit gamma 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LAMC2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
|
|
| G
|
Large1
|
LARGE xylosyl- and glucuronyltransferase 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of LARGE1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,609,004...12,054,707
|
|
| G
|
Ldha
|
lactate dehydrogenase A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LDHA exon; Ethylnitrosourea results in increased mutagenesis of LDHA gene
|
CTD |
PMID:7534515 PMID:16180137 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Lepr
|
leptin receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LEPR gene
|
CTD |
PMID:16724327 |
|
NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215
|
|
| G
|
Lgals3
|
galectin 3
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of LGALS3 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Lhcgr
|
luteinizing hormone/choriogonadotropin receptor
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of LHCGR gene
|
CTD |
PMID:16495775 |
|
NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061
|
|
| G
|
Lhx2
|
LIM homeobox 2
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of LHX2 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645
|
|
| G
|
Lhx4
|
LIM homeobox 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LHX4 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:70,423,768...70,477,337
Ensembl chr13:70,427,399...70,467,505
|
|
| G
|
Lif
|
LIF, interleukin 6 family cytokine
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of LIF mRNA
|
CTD |
PMID:26198647 |
|
NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053
|
|
| G
|
Lmbr1
|
limb development membrane protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LMBR1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:6,649,824...6,820,525
Ensembl chr 4:6,649,821...6,822,238
|
|
| G
|
Lnx2
|
ligand of numb-protein X 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LNX2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:13,119,139...13,184,401
Ensembl chr12:13,119,139...13,184,401
|
|
| G
|
Lpar3
|
lysophosphatidic acid receptor 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LPAR3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197
|
|
| G
|
Lrp2
|
LDL receptor related protein 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LRP2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535
|
|
| G
|
Lrp5
|
LDL receptor related protein 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LRP5 gene
|
CTD |
PMID:18263894 |
|
NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822
|
|
| G
|
Lrp8
|
LDL receptor related protein 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LRP8 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:127,792,236...127,864,207
Ensembl chr 5:127,792,299...127,864,207
|
|
| G
|
Lrrc14
|
leucine rich repeat containing 14
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LRRC14 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:110,311,384...110,317,757
Ensembl chr 7:110,311,369...110,317,760
|
|
| G
|
Lsm3
|
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LSM3 3' UTR; Ethylnitrosourea results in increased mutagenesis of LSM3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 4:125,578,185...125,584,429
Ensembl chr 4:125,578,185...125,584,429
|
|
| G
|
Lta
|
lymphotoxin alpha
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LTA gene
|
CTD |
PMID:18384745 |
|
NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533
|
|
| G
|
Lum
|
lumican
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of LUM mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508
|
|
| G
|
Lxn
|
latexin
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of LXN mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
|
|
| G
|
Ly9
|
lymphocyte antigen 9
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LY9 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:86,610,762...86,633,314
Ensembl chr13:86,611,784...86,657,293
|
|
| G
|
Lypd2
|
Ly6/Plaur domain containing 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of LYPD2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:108,506,545...108,508,582
Ensembl chr 7:108,506,545...108,508,582
|
|
| G
|
Madd
|
MAP-kinase activating death domain
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MADD mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:97,570,787...97,613,509
|
|
| G
|
Man2c1
|
mannosidase, alpha, class 2C, member 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MAN2C1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 8:66,434,480...66,445,649
Ensembl chr 8:66,434,421...66,445,648
|
|
| G
|
Mapk6
|
mitogen-activated protein kinase 6
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of MAPK6 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 8:85,027,141...85,050,236
Ensembl chr 8:85,027,144...85,050,236
|
|
| G
|
Mbd1
|
methyl-CpG binding domain protein 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MBD1; Ethylnitrosourea results in increased expression of MBD1 mRNA
|
CTD |
PMID:19100860 PMID:21154115 |
|
NCBI chr18:70,145,093...70,159,744
Ensembl chr18:70,145,114...70,159,703
|
|
| G
|
Mc1r
|
melanocortin 1 receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MC1R exon; Ethylnitrosourea results in increased mutagenesis of MC1R promoter
|
CTD |
PMID:16300676 |
|
NCBI chr19:68,360,950...68,363,877
Ensembl chr19:68,360,950...68,363,877
|
|
| G
|
Mc3r
|
melanocortin 3 receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MC3R gene
|
CTD |
PMID:16720677 |
|
NCBI chr 3:181,434,776...181,435,873
Ensembl chr 3:181,434,776...181,435,873
|
|
| G
|
Mc4r
|
melanocortin 4 receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MC4R gene
|
CTD |
PMID:16720677 PMID:17143585 |
|
NCBI chr18:62,689,798...62,691,685
|
|
| G
|
Mcm3ap
|
minichromosome maintenance complex component 3 associated protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MCM3AP gene
|
CTD |
PMID:27776689 |
|
NCBI chr20:12,127,060...12,164,651
Ensembl chr20:12,127,060...12,164,651
|
|
| G
|
Mcrs1
|
microspherule protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MCRS1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 7:132,262,719...132,271,533
Ensembl chr 7:132,262,722...132,271,533
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
increases expression
|
EXP ISO
|
Ethylnitrosourea results in increased expression of MDM2 mRNA
|
CTD |
PMID:15954086 PMID:19100860 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
| G
|
Mecp2
|
methyl CpG binding protein 2
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MECP2
|
CTD |
PMID:21154115 |
|
NCBI chr X:156,932,481...156,995,981
Ensembl chr X:156,941,234...156,943,560
|
|
| G
|
Med12l
|
mediator complex subunit 12L
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MED12L mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:145,403,318...145,726,317
Ensembl chr 2:145,404,375...145,723,516
|
|
| G
|
Mettl24
|
methyltransferase like 24
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of METTL24 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr20:45,724,506...45,847,300
Ensembl chr20:45,724,982...45,843,959
|
|
| G
|
Mfsd3
|
major facilitator superfamily domain containing 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MFSD3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 7:110,300,254...110,304,108
Ensembl chr 7:110,302,018...110,304,112
|
|
| G
|
Mfsd4b1
|
major facilitator superfamily domain containing 4B1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MFSD4B1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr20:44,991,384...45,004,590
Ensembl chr20:44,991,384...45,006,161
|
|
| G
|
Mgat2
|
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of MGAT2 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 6:93,392,416...93,394,905
Ensembl chr 6:93,390,555...93,395,176
|
|
| G
|
Mgat5b
|
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MGAT5B intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:102,619,559...102,689,023
Ensembl chr10:102,619,559...102,689,017
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
increases alkylation increases expression
|
ISO EXP
|
Ethylnitrosourea results in increased alkylation of MGMT protein Ethylnitrosourea results in increased expression of MGMT mRNA
|
CTD |
PMID:8823159 PMID:11599795 PMID:15954086 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Mir22
|
microRNA 22
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MIR22 mRNA
|
CTD |
PMID:29777724 |
|
NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425
|
|
| G
|
Mir34a
|
microRNA 34a
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MIR34A mRNA
|
CTD |
PMID:22297810 |
|
NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053
|
|
| G
|
Mir409
|
microRNA 409
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MIR409 mRNA
|
CTD |
PMID:29777724 |
|
NCBI chr 6:134,579,185...134,579,261
|
|
| G
|
Mir425
|
microRNA 425
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MIR425 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 8:118,143,084...118,143,166
Ensembl chr 8:118,143,084...118,143,166
|
|
| G
|
Mir96
|
microRNA 96
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MIR96 gene
|
CTD |
PMID:19363478 |
|
NCBI chr 4:59,755,841...59,755,946
|
|
| G
|
Mlh1
|
mutL homolog 1
|
increases expression multiple interactions
|
ISO
|
Ethylnitrosourea results in increased expression of MLH1 Phytic Acid inhibits the reaction [Ethylnitrosourea results in increased expression of MLH1]
|
CTD |
PMID:21154115 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
|
|
| G
|
Mpo
|
myeloperoxidase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MPO mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
|
|
| G
|
Msh2
|
mutS homolog 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of MSH2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
|
|
| G
|
Msh6
|
mutS homolog 6
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of MSH6 gene
|
CTD |
PMID:16495775 PMID:18417481 |
|
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
|
|
| G
|
Mt-nd1
|
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of ND1 mRNA
|
CTD |
PMID:20438828 |
|
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
increases mutagenesis decreases expression
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MTOR gene Ethylnitrosourea results in decreased expression of MTOR protein
|
CTD |
PMID:15485918 PMID:16724327 PMID:32902906 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Muc4
|
mucin 4, cell surface associated
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MUC4 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:81,513,321...81,575,200
|
|
| G
|
Muc6
|
mucin 6, oligomeric mucus/gel-forming
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MUC6 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:206,155,826...206,194,384
Ensembl chr 1:206,155,593...206,191,864
|
|
| G
|
Myb
|
MYB proto-oncogene, transcription factor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYB gene
|
CTD |
PMID:16724327 |
|
NCBI chr 1:17,759,309...17,793,306
Ensembl chr 1:17,759,309...17,792,547
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of MYC mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Myd88
|
MYD88, innate immune signal transduction adaptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYD88 exon
|
CTD |
PMID:16300676 |
|
NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
|
|
| G
|
Myh2
|
myosin heavy chain 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYH2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:52,355,739...52,382,235
Ensembl chr10:52,355,739...52,382,235
|
|
| G
|
Myo1f
|
myosin IF
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYO1F intron
|
CTD |
PMID:27776689 |
|
NCBI chr 7:15,065,530...15,116,087
Ensembl chr 7:15,065,530...15,116,087
|
|
| G
|
Myo5a
|
myosin VA
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYO5A gene
|
CTD |
PMID:9475716 PMID:9825669 PMID:10517996 PMID:17174358 |
|
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265
|
|
| G
|
Myo6
|
myosin VI
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYO6 gene
|
CTD |
PMID:17329413 |
|
NCBI chr 8:89,967,351...90,122,219
Ensembl chr 8:89,967,377...90,122,215
|
|
| G
|
Myo7a
|
myosin VIIA
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of MYO7A gene
|
CTD |
PMID:15965244 |
|
NCBI chr 1:161,755,110...161,825,397
Ensembl chr 1:161,755,110...161,825,365
|
|
| G
|
Myoc
|
myocilin
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of MYOC gene
|
CTD |
PMID:16495775 |
|
NCBI chr13:77,509,963...77,520,361
Ensembl chr13:77,509,963...77,520,361
|
|
| G
|
Myrfl
|
myelin regulatory factor-like
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MYRFL intron
|
CTD |
PMID:27776689 |
|
NCBI chr 7:54,289,430...54,406,097
Ensembl chr 7:54,289,332...54,405,868
|
|
| G
|
Myt1
|
myelin transcription factor 1
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of MYT1 protein
|
CTD |
PMID:28549617 |
|
NCBI chr 3:189,263,569...189,327,844
Ensembl chr 3:189,263,467...189,327,844
|
|
| G
|
Ncaph2
|
non-SMC condensin II complex, subunit H2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NCAPH2 gene
|
CTD |
PMID:17640884 |
|
NCBI chr 7:122,302,550...122,319,570
Ensembl chr 7:122,300,252...122,319,569
|
|
| G
|
Nckap1
|
NCK-associated protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NCKAP1 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797
|
|
| G
|
Ndn
|
necdin, MAGE family member
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of NDN protein
|
CTD |
PMID:28549617 |
|
NCBI chr 1:125,261,059...125,262,658
Ensembl chr 1:125,260,997...125,262,785
|
|
| G
|
Neil1
|
nei-like DNA glycosylase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NEIL1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 8:66,446,106...66,452,844
Ensembl chr 8:66,445,953...66,452,378
|
|
| G
|
Net1
|
neuroepithelial cell transforming 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of NET1 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270
|
|
| G
|
Neurl2
|
neuralized E3 ubiquitin protein ligase 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NEURL2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:173,985,996...173,988,717
Ensembl chr 3:173,986,857...173,989,043
|
|
| G
|
Nfix
|
nuclear factor I X
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of NFIX mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092
|
|
| G
|
Nfya
|
nuclear transcription factor Y subunit alpha
|
multiple interactions increases activity
|
ISO
|
Ethylnitrosourea promotes the reaction [NFYA protein binds to KRAS exon] Ethylnitrosourea results in increased activity of NFYA protein
|
CTD |
PMID:16271038 |
|
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
|
|
| G
|
Nifk
|
nucleolar protein interacting with the FHA domain of MKI67
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of MKI67IP mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561
|
|
| G
|
Nlgn3
|
neuroligin 3
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NLGN3 gene
|
CTD |
PMID:16495775 |
|
NCBI chr X:70,469,251...70,497,380
Ensembl chr X:70,469,457...70,497,379
|
|
| G
|
Nmur2
|
neuromedin U receptor 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NMUR2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr10:40,666,824...40,682,679
Ensembl chr10:40,645,101...40,682,679
|
|
| G
|
Nol9
|
nucleolar protein 9
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NOL9 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:167,829,249...167,849,364
Ensembl chr 5:167,829,264...167,849,366
|
|
| G
|
Nos1
|
nitric oxide synthase 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NOS1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837
|
|
| G
|
Npr3
|
natriuretic peptide receptor 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NPR3 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066
|
|
| G
|
Npy2r
|
neuropeptide Y receptor Y2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NPY2R gene
|
CTD |
PMID:16495775 |
|
NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:170,200,027...170,210,448
|
|
| G
|
Npy4r
|
neuropeptide Y receptor Y4
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NPY4R gene
|
CTD |
PMID:16495775 |
|
NCBI chr16:9,474,051...9,475,307
Ensembl chr16:9,472,011...9,482,405
|
|
| G
|
Nr0b2
|
nuclear receptor subfamily 0, group B, member 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NR0B2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475
|
|
| G
|
Nr1d1
|
nuclear receptor subfamily 1, group D, member 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NR1D1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812
|
|
| G
|
Nsun7
|
NOP2/Sun RNA methyltransferase family member 7
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NSUN7 gene
|
CTD |
PMID:17442852 |
|
NCBI chr14:42,233,062...42,289,013
Ensembl chr14:42,233,062...42,288,958
|
|
| G
|
Ntrk2
|
neurotrophic receptor tyrosine kinase 2
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NTRK2 gene
|
CTD |
PMID:16495775 |
|
NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628
|
|
| G
|
Nts
|
neurotensin
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of NTS gene
|
CTD |
PMID:16495775 |
|
NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961
|
|
| G
|
Nup133
|
nucleoporin 133
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of NUP133 gene
|
CTD |
PMID:15755804 |
|
NCBI chr19:68,789,065...68,838,692
Ensembl chr19:68,789,065...68,838,692
|
|
| G
|
Obscn
|
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OBSCN mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:44,273,686...44,419,275
Ensembl chr10:44,288,866...44,419,297
|
|
| G
|
Oca2
|
OCA2 melanosomal transmembrane protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OCA2 gene
|
CTD |
PMID:17174358 |
|
NCBI chr 1:116,252,026...116,581,838
Ensembl chr 1:116,251,796...116,581,838
|
|
| G
|
Oprl1
|
opioid related nociceptin receptor 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of OPRL1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:189,212,175...189,217,426
|
|
| G
|
Oprm1
|
opioid receptor, mu 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of OPRM1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756
|
|
| G
|
Or10d3
|
olfactory receptor family 10 subfamily D member 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OR10D3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 8:48,734,800...48,735,738
Ensembl chr 8:48,734,800...48,735,738
|
|
| G
|
Or5e1
|
olfactory receptor family 5 subfamily E member 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OR5E1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:172,159,177...172,160,112
Ensembl chr 1:172,159,177...172,160,112
|
|
| G
|
Osbp2
|
oxysterol binding protein 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OSBP2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr14:82,808,693...82,970,386
Ensembl chr14:82,808,693...82,970,532
|
|
| G
|
Osbpl6
|
oxysterol binding protein-like 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OSBPL6 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:81,751,020...81,948,186
Ensembl chr 3:81,750,982...81,946,615
|
|
| G
|
Otof
|
otoferlin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OTOF exon; Ethylnitrosourea results in increased mutagenesis of OTOF gene
|
CTD |
PMID:17329413 PMID:17967520 |
|
NCBI chr 6:31,647,869...31,744,476
Ensembl chr 6:31,647,914...31,744,476
|
|
| G
|
Otop1
|
otopetrin 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of OTOP1 gene
|
CTD |
PMID:16972005 |
|
NCBI chr14:76,717,330...76,744,785
Ensembl chr14:76,716,329...76,744,785
|
|
| G
|
Pak4
|
p21 (RAC1) activated kinase 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PAK4 exon
|
CTD |
PMID:16300676 |
|
NCBI chr 1:92,977,437...93,016,721
Ensembl chr 1:92,977,437...93,016,721
|
|
| G
|
Parp9
|
poly (ADP-ribose) polymerase family, member 9
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PARP9 gene
|
CTD |
PMID:27776689 |
|
NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608
|
|
| G
|
Pax3
|
paired box 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PAX3 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141
|
|
| G
|
Pax6
|
paired box 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PAX6 exon; Ethylnitrosourea results in increased mutagenesis of PAX6 gene; Ethylnitrosourea results in increased mutagenesis of PAX6 intron
|
CTD |
PMID:16303964 PMID:16724327 |
|
NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763
|
|
| G
|
Pcdh15
|
protocadherin related 15
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PCDH15 gene
|
CTD |
PMID:15811708 |
|
NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958
|
|
| G
|
Pcdha4
|
protocadherin alpha 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PCDHA4 intron
|
CTD |
PMID:27776689 |
|
NCBI chr18:28,688,274...29,120,227
Ensembl chr18:28,855,256...29,120,227
|
|
| G
|
Pcdhb19
|
protocadherin beta 19
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PCDHB19 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr18:29,478,848...29,481,656
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
increases expression
|
EXP ISO
|
Ethylnitrosourea results in increased expression of PCNA mRNA Ethylnitrosourea results in increased expression of PCNA protein
|
CTD |
PMID:15954086 PMID:28549617 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pcsk5
|
proprotein convertase subtilisin/kexin type 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PCSK5 gene
|
CTD |
PMID:18519639 |
|
NCBI chr 1:224,263,823...224,694,350
Ensembl chr 1:224,264,678...224,694,347
|
|
| G
|
Pde4c
|
phosphodiesterase 4C
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PDE4C mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr16:18,724,703...18,745,528
Ensembl chr16:18,725,674...18,744,037
|
|
| G
|
Pde6b
|
phosphodiesterase 6B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PDE6B gene
|
CTD |
PMID:16123450 |
|
NCBI chr14:1,468,302...1,511,435
Ensembl chr14:1,468,302...1,511,435
|
|
| G
|
Pdp1
|
pyruvate dehydrogenase phosphatase catalytic subunit 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of PDP1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960
|
|
| G
|
Pdpk1
|
3-phosphoinositide dependent protein kinase-1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of PDPK1 protein
|
CTD |
PMID:32902906 |
|
NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181
|
|
| G
|
Phf2
|
PHD finger protein 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PHF2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr17:15,989,594...16,057,583
Ensembl chr17:15,981,604...16,057,583
|
|
| G
|
Piga
|
phosphatidylinositol glycan anchor biosynthesis, class A
|
multiple interactions increases mutagenesis
|
EXP ISO
|
[Ethylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [Ethylnitrosourea results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein; Ethylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein Ethylnitrosourea results in increased mutagenesis of PIGA; Ethylnitrosourea results in increased mutagenesis of PIGA gene
|
CTD |
PMID:19965957 PMID:20202993 PMID:20857433 PMID:21729764 PMID:22167886 PMID:22730214 PMID:22923490 PMID:24105957 PMID:27931811 PMID:29362862 PMID:30439388 More...
|
|
NCBI chr X:33,672,832...33,687,747
Ensembl chr X:33,674,923...33,687,636
|
|
| G
|
Pink1
|
PTEN induced kinase 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of PINK1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950
|
|
| G
|
Pitpnm1
|
phosphatidylinositol transfer protein, membrane-associated 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PITPNM1 gene; Ethylnitrosourea results in increased mutagenesis of PITPNM1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:210,823,568...210,836,989
Ensembl chr 1:210,823,565...210,836,990
|
|
| G
|
Pjvk
|
pejvakin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PJVK gene
|
CTD |
PMID:17329413 |
|
NCBI chr 3:82,002,106...82,012,273
Ensembl chr 3:82,002,368...82,012,451
|
|
| G
|
Pkd1
|
polycystin 1, transient receptor potential channel interacting
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PKD1 gene; Ethylnitrosourea results in increased mutagenesis of PKD1 mRNA
|
CTD |
PMID:16724327 PMID:27776689 |
|
NCBI chr10:14,077,733...14,125,682
Ensembl chr10:14,078,679...14,125,681
|
|
| G
|
Pkdrej
|
polycystin family receptor for egg jelly
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PKDREJ mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:118,788,939...118,795,313
Ensembl chr 7:118,784,555...118,797,948
|
|
| G
|
Plaa
|
phospholipase A2, activating protein
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of PLAA mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 5:114,544,327...114,576,023
Ensembl chr 5:114,544,325...114,576,109
|
|
| G
|
Plcb3
|
phospholipase C beta 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLCB3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583
|
|
| G
|
Plcg2
|
phospholipase C, gamma 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLCG2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684
|
|
| G
|
Plekhm3
|
pleckstrin homology domain containing M3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLEKHM3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:73,659,998...73,819,079
Ensembl chr 9:73,664,817...73,799,503
|
|
| G
|
Plin1
|
perilipin 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLIN1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206
|
|
| G
|
Plin3
|
perilipin 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLIN3 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:1,198,336...1,210,212
Ensembl chr 9:1,198,336...1,210,231
|
|
| G
|
Plk2
|
polo-like kinase 2
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of PLK2 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296
|
|
| G
|
Plxnb2
|
plexin B2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PLXNB2 intron; Ethylnitrosourea results in increased mutagenesis of PLXNB2 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746
|
|
| G
|
Pmch
|
pro-melanin-concentrating hormone
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of PMCH gene
|
CTD |
PMID:16495775 |
|
NCBI chr 7:24,399,404...24,400,720
Ensembl chr 7:24,399,404...24,400,720
|
|
| G
|
Pmp22
|
peripheral myelin protein 22
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PMP22 gene
|
CTD |
PMID:16724327 |
|
NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940
|
|
| G
|
Poglut1
|
protein O-glucosyltransferase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of POGLUT1 gene
|
CTD |
PMID:15755804 |
|
NCBI chr11:75,704,119...75,731,964
Ensembl chr11:75,703,833...75,733,519
|
|
| G
|
Pold1
|
DNA polymerase delta 1, catalytic subunit
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of POLD1 3' UTR; Ethylnitrosourea results in increased mutagenesis of POLD1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982
|
|
| G
|
Polq
|
DNA polymerase theta
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of POLQ gene
|
CTD |
PMID:16724327 |
|
NCBI chr11:77,179,190...77,281,270
Ensembl chr11:77,179,209...77,281,268
|
|
| G
|
Polr1e
|
RNA polymerase I subunit E
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of POLR1E mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:64,075,123...64,090,900
Ensembl chr 5:64,075,122...64,091,039
|
|
| G
|
Pomt1
|
protein-O-mannosyltransferase 1
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of POMT1 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 3:35,918,370...35,936,330
Ensembl chr 3:35,918,188...35,936,364
|
|
| G
|
Ppara
|
peroxisome proliferator activated receptor alpha
|
decreases expression decreases activity
|
ISO
|
Ethylnitrosourea results in decreased expression of PPARA mRNA Ethylnitrosourea results in decreased activity of PPARA protein
|
CTD |
PMID:25689681 PMID:30203046 |
|
NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
|
|
| G
|
Ppfia3
|
PTPRF interacting protein alpha 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PPFIA3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:104,953,598...104,982,373
Ensembl chr 1:104,953,598...104,982,278
|
|
| G
|
Ppia
|
peptidylprolyl isomerase A
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of PPIA mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115
|
|
| G
|
Ppp1r21
|
protein phosphatase 1, regulatory subunit 21
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PPP1R21 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 6:11,655,059...11,724,219
Ensembl chr 6:11,655,059...11,724,219
|
|
| G
|
Ppp1r3c
|
protein phosphatase 1, regulatory subunit 3C
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of PPP1R3C mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835
|
|
| G
|
Prim1
|
DNA primase subunit 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of PRIM1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 7:1,031,436...1,047,134
|
|
| G
|
Prkar1b
|
protein kinase cAMP-dependent type I regulatory subunit beta
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PRKAR1B mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766
|
|
| G
|
Prkar2b
|
protein kinase cAMP-dependent type II regulatory subunit beta
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of PRKAR2B mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411
|
|
| G
|
Prss1
|
serine protease 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TRY10 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:71,331,249...71,334,452
Ensembl chr 4:71,331,246...71,334,452
|
|
| G
|
Psmc2
|
proteasome 26S subunit, ATPase 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PSMC2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390
|
|
| G
|
Psmd13
|
proteasome 26S subunit, non-ATPase 13
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PSMD13 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:205,393,746...205,411,651
|
|
| G
|
Pten
|
phosphatase and tensin homolog
|
increases mutagenesis decreases expression
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PTEN gene Ethylnitrosourea results in decreased expression of PTEN protein
|
CTD |
PMID:15755804 PMID:16724327 PMID:32902906 |
|
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression multiple interactions
|
ISO
|
Ethylnitrosourea results in increased expression of PTGS2 Phytic Acid inhibits the reaction [Ethylnitrosourea results in increased expression of PTGS2]
|
CTD |
PMID:21154115 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Ptpn18
|
protein tyrosine phosphatase, non-receptor type 18
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PTPN18 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:44,166,571...44,185,885
Ensembl chr 9:44,168,269...44,186,917
|
|
| G
|
Ptprc
|
protein tyrosine phosphatase, receptor type, C
|
increases mutagenesis decreases expression
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of PTPRC gene Ethylnitrosourea results in decreased expression of PTPRC protein
|
CTD |
PMID:16724327 PMID:27725143 |
|
NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746
|
|
| G
|
Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of PTTG1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
|
|
| G
|
Qki
|
QKI, KH domain containing RNA binding
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of QKI gene
|
CTD |
PMID:16245024 |
|
NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:52,935,382...53,047,337
|
|
| G
|
Rab14
|
RAB14, member RAS oncogene family
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of RAB14 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 3:38,899,430...38,920,572
Ensembl chr 3:38,901,400...38,912,273
|
|
| G
|
Rab23
|
RAB23, member RAS oncogene family
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RAB23 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 9:43,440,047...43,463,327
Ensembl chr 9:43,440,273...43,463,325
|
|
| G
|
Rab3a
|
RAB3A, member RAS oncogene family
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RAB3A gene
|
CTD |
PMID:16724327 |
|
NCBI chr16:18,718,164...18,722,273
Ensembl chr16:18,718,167...18,721,842
|
|
| G
|
Rapgef6
|
Rap guanine nucleotide exchange factor 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RAPGEF6 intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:39,156,573...39,324,947
Ensembl chr10:39,156,620...39,324,946
|
|
| G
|
Rasa3
|
RAS p21 protein activator 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RASA3 intron
|
CTD |
PMID:27776689 |
|
NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984
|
|
| G
|
Rasgrf1
|
RAS protein-specific guanine nucleotide-releasing factor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RASGRF1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:99,324,749...99,454,089
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of RB1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Rbm22
|
RNA binding motif protein 22
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RBM22 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr18:56,283,807...56,294,615
Ensembl chr18:56,283,770...56,295,073
|
|
| G
|
Rcan1
|
regulator of calcineurin 1
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of RCAN1 mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236
|
|
| G
|
Rdh10
|
retinol dehydrogenase 10
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RDH10 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:7,969,931...7,998,834
Ensembl chr 5:7,971,705...7,999,019
|
|
| G
|
Recql4
|
RecQ like helicase 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RECQL4 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258
|
|
| G
|
Reln
|
reelin
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of RELN gene
|
CTD |
PMID:16495775 |
|
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
|
|
| G
|
Repin1
|
replication initiator 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of REPIN1 3' UTR
|
CTD |
PMID:27776689 |
|
NCBI chr 4:78,879,910...78,885,143
Ensembl chr 4:78,880,976...78,886,413
|
|
| G
|
Rfx4
|
regulatory factor X4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RFX4 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:20,741,079...20,902,851
|
|
| G
|
Rgs2
|
regulator of G-protein signaling 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RGS2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697
|
|
| G
|
Rho
|
rhodopsin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RHO gene
|
CTD |
PMID:16332273 |
|
NCBI chr 4:150,653,205...150,658,367
Ensembl chr 4:150,653,205...150,658,367
|
|
| G
|
Rnf38
|
ring finger protein 38
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RNF38 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:63,154,507...63,263,138
Ensembl chr 5:63,154,507...63,263,137
|
|
| G
|
Rpl27a
|
ribosomal protein L27A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RPL27A gene
|
CTD |
PMID:21674502 |
|
NCBI chr 1:172,971,957...172,977,591
|
|
| G
|
Rpl7
|
ribosomal protein L7
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RPL7 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451
|
|
| G
|
Rprd1a
|
regulation of nuclear pre-mRNA domain containing 1A
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of RPRD1A gene
|
CTD |
PMID:16495775 |
|
NCBI chr18:16,066,169...16,114,102
Ensembl chr18:16,066,169...16,114,282
|
|
| G
|
Rptor
|
regulatory associated protein of MTOR, complex 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RPTOR intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:105,376,943...105,675,416
Ensembl chr10:105,376,943...105,675,413
|
|
| G
|
Rrm2b
|
ribonucleotide reductase regulatory TP53 inducible subunit M2B
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of RRM2B mRNA
|
CTD |
PMID:21704725 |
|
NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670
|
|
| G
|
Rs1
|
retinoschisin 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RS1 intron
|
CTD |
PMID:16088326 |
|
NCBI chr X:37,771,135...37,800,894
Ensembl chr X:37,771,135...37,800,894
|
|
| G
|
Rtel1
|
regulator of telomere elongation helicase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RTEL1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709
|
|
| G
|
Rtf1
|
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of RTF1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:127,113,171...127,172,761
Ensembl chr 3:127,113,163...127,172,761
|
|
| G
|
Scd
|
stearoyl-CoA desaturase
|
decreases expression
|
EXP
|
Ethylnitrosourea results in decreased expression of SCD1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
|
|
| G
|
Scn8a
|
sodium voltage-gated channel alpha subunit 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SCN8A exon; Ethylnitrosourea results in increased mutagenesis of SCN8A gene
|
CTD |
PMID:15170223 PMID:19261867 |
|
NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:133,861,227...134,030,026
|
|
| G
|
Scnn1g
|
sodium channel epithelial 1 subunit gamma
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SCNN1G intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:185,736,191...185,770,097
|
|
| G
|
Scube2
|
signal peptide, CUB domain and EGF like domain containing 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SCUBE2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:173,264,862...173,341,323
Ensembl chr 1:173,264,865...173,334,372
|
|
| G
|
Sema3c
|
semaphorin 3C
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SEMA3C gene
|
CTD |
PMID:15548583 |
|
NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:18,538,454...18,701,740
|
|
| G
|
Sf3b2
|
splicing factor 3b, subunit 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SF3B2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:211,999,777...212,040,686
Ensembl chr 1:211,999,778...212,020,113
|
|
| G
|
Sfi1
|
SFI1 centrin binding protein
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SFI1 gene; Ethylnitrosourea results in increased mutagenesis of SFI1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr14:82,215,423...82,272,811
Ensembl chr14:82,214,608...82,272,711
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of SGK1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
| G
|
Sh2d4a
|
SH2 domain containing 4A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SH2D4A intron
|
CTD |
PMID:27776689 |
|
NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974
|
|
| G
|
Shh
|
sonic hedgehog signaling molecule
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SHH enhancer
|
CTD |
PMID:17049204 |
|
NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901
|
|
| G
|
Sim1
|
SIM bHLH transcription factor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SIM1 gene
|
CTD |
PMID:18056790 |
|
NCBI chr20:55,409,814...55,489,450
Ensembl chr20:55,410,577...55,489,449
|
|
| G
|
Slc4a1
|
solute carrier family 4 member 1 (Diego blood group)
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SLC4A1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258
|
|
| G
|
Slc6a3
|
solute carrier family 6 member 3
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of SLC6A3 gene
|
CTD |
PMID:16495775 |
|
NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962
|
|
| G
|
Slc6a4
|
solute carrier family 6 member 4
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of SLC6A4 gene
|
CTD |
PMID:16495775 |
|
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
|
|
| G
|
Slc6a8
|
solute carrier family 6 member 8
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of SLC6A8 gene
|
CTD |
PMID:16495775 |
|
NCBI chr X:156,536,017...156,545,321
Ensembl chr X:156,536,017...156,545,321
|
|
| G
|
Slc8b1
|
solute carrier family 8 member B1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SLC8B1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:41,690,333...41,713,657
Ensembl chr12:41,690,334...41,713,601
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| G
|
Slco2a1
|
solute carrier organic anion transporter family, member 2a1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SLCO2A1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:112,467,160...112,551,921
|
|
| G
|
Slfn5
|
schlafen family member 5
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SLFN5 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:68,378,440...68,392,515
Ensembl chr10:68,378,449...68,392,544
|
|
| G
|
Smad2
|
SMAD family member 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SMAD2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
|
|
| G
|
Smad4
|
SMAD family member 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SMAD4 gene
|
CTD |
PMID:16724327 |
|
NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684
|
|
| G
|
Smarcb1
|
SWI/SNF related BAF chromatin remodeling complex subunit B1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SMARCB1 gene
|
CTD |
PMID:27776689 |
|
NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055
|
|
| G
|
Smo
|
smoothened, frizzled class receptor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SMO gene
|
CTD |
PMID:15755804 PMID:16724327 |
|
NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281
|
|
| G
|
Snn
|
stannin
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of SNN mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr10:5,079,885...5,088,565
Ensembl chr 1:82,440,586...82,441,390 Ensembl chr10:82,440,586...82,441,390
|
|
| G
|
Snora75
|
small nucleolar RNA, H/ACA box 75
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SNORA75 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 9:94,448,219...94,448,355
Ensembl chr 9:94,448,219...94,448,355
|
|
| G
|
Sod1
|
superoxide dismutase 1
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of SOD1 mRNA
|
CTD |
PMID:20438828 |
|
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
|
|
| G
|
Sowahb
|
sosondowah ankyrin repeat domain family member B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SOWAHB mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr14:15,313,561...15,317,396
Ensembl chr14:15,309,246...15,321,591
|
|
| G
|
Sparc
|
secreted protein acidic and cysteine rich
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of SPARC mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268
|
|
| G
|
Spata25
|
spermatogenesis associated 25
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPATA25 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 3:173,981,863...173,983,818
Ensembl chr 3:173,981,866...173,983,818
|
|
| G
|
Speg
|
striated muscle enriched protein kinase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPEG mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 9:84,314,387...84,371,816
Ensembl chr 9:84,314,387...84,371,813
|
|
| G
|
Spg11
|
SPG11 vesicle trafficking associated, spatacsin
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPG11 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 3:129,453,118...129,526,469
Ensembl chr 3:129,461,477...129,526,742
|
|
| G
|
Spib
|
Spi-B transcription factor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPIB gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:104,155,456...104,161,311
Ensembl chr 1:104,155,464...104,161,517
|
|
| G
|
Spint1
|
serine peptidase inhibitor, Kunitz type 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPINT1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 3:126,685,017...126,697,957
Ensembl chr 3:126,685,422...126,697,956
|
|
| G
|
Spon2
|
spondin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SPON2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr14:81,713,070...81,742,510
Ensembl chr14:81,731,188...81,742,609
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of SPP1 mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Stat1
|
signal transducer and activator of transcription 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of STAT1 gene
|
CTD |
PMID:16688530 PMID:16724327 |
|
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stat3
|
signal transducer and activator of transcription 3
|
decreases phosphorylation increases mutagenesis
|
ISO
|
Ethylnitrosourea results in decreased phosphorylation of STAT3 protein Ethylnitrosourea results in increased mutagenesis of STAT3 mRNA
|
CTD |
PMID:27725143 PMID:27776689 |
|
NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
|
|
| G
|
Stat5a
|
signal transducer and activator of transcription 5A
|
increases phosphorylation
|
ISO
|
Ethylnitrosourea results in increased phosphorylation of STAT5 protein
|
CTD |
PMID:27725143 |
|
NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184
|
|
| G
|
Stat5b
|
signal transducer and activator of transcription 5B
|
increases activity
|
ISO
|
Ethylnitrosourea results in increased activity of STAT5B protein
|
CTD |
PMID:30114225 |
|
NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990
|
|
| G
|
Strip1
|
striatin interacting protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of STRIP1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 2:197,936,569...197,956,515
Ensembl chr 2:197,936,569...197,956,865
|
|
| G
|
Stx2
|
syntaxin 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of STX2 gene
|
CTD |
PMID:18277055 |
|
NCBI chr12:33,315,447...33,350,788
Ensembl chr12:33,315,750...33,350,788
|
|
| G
|
Stxbp4
|
syntaxin binding protein 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of STXBP4 gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:75,798,938...75,955,817
Ensembl chr10:75,798,938...75,955,737
|
|
| G
|
Syne2
|
spectrin repeat containing nuclear envelope protein 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of SYNE2 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 6:100,272,729...100,586,364
Ensembl chr 6:100,272,729...100,583,723
|
|
| G
|
Syp
|
synaptophysin
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of SYP gene
|
CTD |
PMID:16495775 |
|
NCBI chr X:17,521,348...17,536,449
Ensembl chr X:17,521,348...17,536,984
|
|
| G
|
Tbcd
|
tubulin folding cofactor D
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TBCD intron
|
CTD |
PMID:27776689 |
|
NCBI chr10:107,215,626...107,372,398
Ensembl chr10:107,215,633...107,372,402
|
|
| G
|
Tbx6
|
T-box transcription factor 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TBX6 gene
|
CTD |
PMID:15755804 PMID:16724327 |
|
NCBI chr 1:190,818,397...190,823,824
Ensembl chr 1:190,819,229...190,823,138
|
|
| G
|
Tek
|
TEK receptor tyrosine kinase
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of TEK protein
|
CTD |
PMID:28549617 |
|
NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991
|
|
| G
|
Tex46
|
testis expressed 46
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TEX46 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 5:154,132,763...154,137,196
Ensembl chr 5:154,132,763...154,137,196
|
|
| G
|
Tfcp2l1
|
transcription factor CP2-like 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TFCP2L1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr13:32,286,643...32,346,671
Ensembl chr13:32,286,643...32,346,671
|
|
| G
|
Tfrc
|
transferrin receptor
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of TFRC protein
|
CTD |
PMID:27725143 |
|
NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318
|
|
| G
|
Th
|
tyrosine hydroxylase
|
increases mutagenesis
|
EXP
|
Ethylnitrosourea results in increased mutagenesis of TH gene
|
CTD |
PMID:16495775 |
|
NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
|
|
| G
|
Ticam1
|
TIR domain containing adaptor molecule 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TICAM1 gene
|
CTD |
PMID:16724327 PMID:27776689 |
|
NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892
|
|
| G
|
Tlr8
|
toll-like receptor 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TLR8 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr X:30,708,714...30,733,104
Ensembl chr X:30,708,033...30,737,079
|
|
| G
|
Tlr9
|
toll-like receptor 9
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TLR9 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148
|
|
| G
|
Tmed4
|
transmembrane p24 trafficking protein 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TMED4 gene; Ethylnitrosourea results in increased mutagenesis of TMED4 intron
|
CTD |
PMID:27776689 |
|
NCBI chr14:85,338,980...85,343,577
Ensembl chr14:85,338,980...85,343,577
|
|
| G
|
Tmem8b
|
transmembrane protein 8B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TMEM8B intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:62,715,238...62,744,187
Ensembl chr 5:62,715,203...62,744,174
|
|
| G
|
Tmem91
|
transmembrane protein 91
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TMEM91 3' UTR; Ethylnitrosourea results in increased mutagenesis of TMEM91 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:90,307,264...90,314,796
Ensembl chr 1:90,306,289...90,313,320
|
|
| G
|
Tmprss7
|
transmembrane serine protease 7
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TMPRSS7 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:68,583,710...68,629,200
Ensembl chr11:68,586,092...68,629,145
|
|
| G
|
Tnf
|
tumor necrosis factor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TNF exon
|
CTD |
PMID:16751399 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tp53
|
tumor protein p53
|
increases mutagenesis decreases expression multiple interactions increases expression increases response to substance affects response to substance
|
EXP ISO
|
Ethylnitrosourea results in increased mutagenesis of TP53 gene Ethylnitrosourea results in decreased expression of TRP53 protein [Ethylnitrosourea results in increased mutagenesis of TP53 gene] which results in decreased activity of TP53 protein Ethylnitrosourea results in increased expression of TRP53 protein TRP53 gene mutant form results in increased susceptibility to Ethylnitrosourea TRP53 affects the susceptibility to Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of TRP53 exon; Ethylnitrosourea results in increased mutagenesis of TRP53 gene
|
CTD |
PMID:9667752 PMID:11053539 PMID:14715658 PMID:15790496 PMID:16357521 PMID:16436596 PMID:16495775 PMID:16724327 PMID:28549617 More...
|
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
| G
|
Trim11
|
tripartite motif-containing 11
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TRIM11 gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:44,255,019...44,270,711
Ensembl chr10:44,257,874...44,270,711
|
|
| G
|
Trim60
|
tripartite motif containing 60
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TRIM60 intron
|
CTD |
PMID:27776689 |
|
NCBI chr16:29,489,264...29,490,876
|
|
| G
|
Trpm4
|
transient receptor potential cation channel, subfamily M, member 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TRPM4 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:104,918,462...104,948,653
|
|
| G
|
Tsr3
|
TSR3 ribosome maturation factor
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TSR3 gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:14,761,656...14,764,061
Ensembl chr10:14,761,663...14,764,061
|
|
| G
|
Ttc13
|
tetratricopeptide repeat domain 13
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TTC13 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:69,534,989...69,589,590
Ensembl chr19:69,534,989...69,589,563
|
|
| G
|
Ttc21b
|
tetratricopeptide repeat domain 21B
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TTC21B gene
|
CTD |
PMID:18327258 |
|
NCBI chr 3:71,269,425...71,343,936
Ensembl chr 3:71,269,425...71,343,936
|
|
| G
|
Ttc8
|
tetratricopeptide repeat domain 8
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TTC8 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 6:123,927,657...124,025,354
Ensembl chr 6:123,927,907...123,982,117
|
|
| G
|
Ttll10
|
tubulin tyrosine ligase like 10
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TTLL10 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 5:171,912,371...171,937,733
Ensembl chr 5:171,912,376...171,926,337
|
|
| G
|
Tubb4b
|
tubulin, beta 4B class IVb
|
increases expression
|
ISO
|
Ethylnitrosourea results in increased expression of TUBB4B mRNA
|
CTD |
PMID:19100860 |
|
NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:28,435,148...28,439,719
|
|
| G
|
Twist1
|
twist family bHLH transcription factor 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TWIST1 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965
|
|
| G
|
Txnrd3
|
thioredoxin reductase 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TXNRD3 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 4:123,629,768...123,669,713
Ensembl chr 4:123,648,750...123,668,552
|
|
| G
|
Tyr
|
tyrosinase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TYR gene
|
CTD |
PMID:9475716 PMID:16180137 PMID:17174358 |
|
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
|
|
| G
|
Tyrp1
|
tyrosinase-related protein 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of TYRP1 gene
|
CTD |
PMID:9475716 PMID:10517996 PMID:17174358 |
|
NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:100,327,125...100,345,657
|
|
| G
|
U2af1l4
|
U2 small nuclear RNA auxiliary factor 1-like 4
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of U2AF1L4 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:94,943,684...94,945,906
Ensembl chr 1:94,942,544...94,946,391
|
|
| G
|
Ubash3a
|
ubiquitin associated and SH3 domain containing, A
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UBASH3A intron
|
CTD |
PMID:27776689 |
|
NCBI chr20:9,292,819...9,336,036
Ensembl chr20:9,287,590...9,344,772
|
|
| G
|
Ugcg
|
UDP-glucose ceramide glucosyltransferase
|
increases expression
|
EXP
|
Ethylnitrosourea results in increased expression of UGCG mRNA
|
CTD |
PMID:15954086 |
|
NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417
|
|
| G
|
Ugdh
|
UDP-glucose 6-dehydrogenase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UGDH gene
|
CTD |
PMID:15755804 |
|
NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629
|
|
| G
|
Ugt3a1
|
UDP glycosyltransferase family 3 member A1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UGT3A1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 2:60,062,257...60,077,354
Ensembl chr 2:60,061,775...60,077,354
|
|
| G
|
Ulk1
|
unc-51 like autophagy activating kinase 1
|
decreases phosphorylation multiple interactions
|
ISO
|
Ethylnitrosourea results in decreased phosphorylation of ULK1 protein Quercetin inhibits the reaction [Ethylnitrosourea results in decreased phosphorylation of ULK1 protein]
|
CTD |
PMID:32902906 |
|
NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746
|
|
| G
|
Unc13d
|
unc-13 homolog D
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UNC13D mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:101,795,652...101,810,409
Ensembl chr10:101,795,652...101,810,409
|
|
| G
|
Unkl
|
unk like zinc finger
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UNKL gene
|
CTD |
PMID:27776689 |
|
NCBI chr10:14,710,627...14,756,725
Ensembl chr10:14,710,563...14,756,724
|
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| G
|
Upf1
|
UPF1, RNA helicase and ATPase
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UPF1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr16:19,110,531...19,131,327
Ensembl chr16:19,110,538...19,131,327
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| G
|
Usp16
|
ubiquitin specific peptidase 16
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of USP16 gene
|
CTD |
PMID:27776689 |
|
NCBI chr11:40,166,651...40,196,792
Ensembl chr11:40,167,692...40,196,823
|
|
| G
|
Usp29
|
ubiquitin specific peptidase 29
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of USP29 exon
|
CTD |
PMID:16300676 |
|
NCBI chr 1:75,907,331...75,959,896
Ensembl chr 1:75,906,632...76,131,141
|
|
| G
|
Utp20
|
UTP20 small subunit processome component
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of UTP20 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 7:25,022,029...25,103,024
Ensembl chr 7:25,022,036...25,103,041
|
|
| G
|
Vat1
|
vesicle amine transport 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of VAT1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,889,793...86,897,411
|
|
| G
|
Vkorc1l1
|
vitamin K epoxide reductase complex, subunit 1-like 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of VKORC1L1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr12:32,354,078...32,404,327
|
|
| G
|
Wdfy3
|
WD repeat and FYVE domain containing 3
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of WDFY3 intron
|
CTD |
PMID:27776689 |
|
NCBI chr14:7,873,946...8,115,002
Ensembl chr14:7,911,151...8,114,993
|
|
| G
|
Wdr6
|
WD repeat domain 6
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of WDR6 gene
|
CTD |
PMID:27776689 |
|
NCBI chr 8:118,146,608...118,153,024
Ensembl chr 8:118,146,608...118,153,092
|
|
| G
|
Xrcc1
|
X-ray repair cross complementing 1
|
decreases expression
|
ISO
|
Ethylnitrosourea results in decreased expression of XRCC1 mRNA
|
CTD |
PMID:21071726 |
|
NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613
|
|
| G
|
Xrcc3
|
X-ray repair cross complementing 3
|
affects response to substance
|
ISO
|
XRCC3 gene polymorphism affects the susceptibility to Ethylnitrosourea
|
CTD |
PMID:17158087 |
|
NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822
|
|
| G
|
Xxylt1
|
xyloside xylosyltransferase 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of XXYLT1 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr11:83,163,432...83,295,879
Ensembl chr11:83,163,189...83,295,988
|
|
| G
|
Ybey
|
ybeY metalloendoribonuclease
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of YBEY intron
|
CTD |
PMID:27776689 |
|
NCBI chr20:12,164,678...12,175,150
Ensembl chr20:12,164,723...12,174,199
|
|
| G
|
Zap70
|
zeta chain of T cell receptor associated protein kinase 70
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZAP70 gene
|
CTD |
PMID:17767948 |
|
NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:46,485,598...46,509,062
|
|
| G
|
Zdhhc14
|
zinc finger DHHC-type palmitoyltransferase 14
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZDHHC14 intron
|
CTD |
PMID:27776689 |
|
NCBI chr 1:48,473,860...48,746,201
Ensembl chr 1:48,474,274...48,744,413
|
|
| G
|
Zfp110
|
zinc finger protein 110
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZFP110 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr 1:82,509,563...82,533,294
Ensembl chr 1:82,517,769...82,533,292
|
|
| G
|
Zfp319
|
zinc finger protein 319
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZFP319 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr19:9,708,881...9,712,860
Ensembl chr19:9,707,983...9,728,711
|
|
| G
|
Zfp568
|
zinc finger protein 568
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZFP568 gene
|
CTD |
PMID:15755804 |
|
NCBI chr 1:94,334,011...94,385,166
Ensembl chr 1:94,334,983...94,393,003
|
|
| G
|
Zfpm2
|
zinc finger protein, multitype 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZFPM2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr 7:73,563,732...74,001,041
Ensembl chr 7:73,563,732...74,001,041
|
|
| G
|
Zic2
|
Zic family member 2
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZIC2 gene
|
CTD |
PMID:16724327 |
|
NCBI chr15:105,982,711...105,988,167
Ensembl chr15:105,983,342...105,988,167
|
|
| G
|
Zmiz1
|
zinc finger, MIZ-type containing 1
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZMIZ1 intron
|
CTD |
PMID:27776689 |
|
NCBI chr16:1,033,983...1,239,425
Ensembl chr16:1,034,020...1,239,406
|
|
| G
|
Znf750
|
zinc finger protein 750
|
increases mutagenesis
|
ISO
|
Ethylnitrosourea results in increased mutagenesis of ZFP750 mRNA
|
CTD |
PMID:27776689 |
|
NCBI chr10:107,270,926...107,279,904
Ensembl chr10:107,270,763...107,279,300
|
|
|
|
| G
|
Abl1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ABL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846
|
|
| G
|
Acox2
|
acyl-CoA oxidase 2
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of ACOX2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392
|
|
| G
|
Adam10
|
ADAM metallopeptidase domain 10
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ADAM10 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600
|
|
| G
|
Agt
|
angiotensinogen
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
|
|
| G
|
Aifm1
|
apoptosis inducing factor, mitochondria associated 1
|
multiple interactions increases localization
|
ISO
|
benzamide inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]; phenanthridone inhibits the reaction [Methylnitronitrosoguanidine results in increased localization of AIFM1 protein]
|
CTD |
PMID:15589979 |
|
NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of AKT1 mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
|
Alb
|
albumin
|
decreases secretion
|
EXP
|
Methylnitronitrosoguanidine results in decreased secretion of ALB protein
|
CTD |
PMID:15772367 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
|
|
| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of ALDH1A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ALPL mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
|
|
| G
|
Ambp
|
alpha-1-microglobulin/bikunin precursor
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of AMBP mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850
|
|
| G
|
Anxa5
|
annexin A5
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of ANXA5 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400
|
|
| G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
affects response to substance decreases expression multiple interactions
|
ISO
|
APAF1 protein affects the susceptibility to Methylnitronitrosoguanidine Methylnitronitrosoguanidine results in decreased expression of APAF1 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of APAF1 protein]
|
CTD |
PMID:16019050 PMID:20434464 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of APC mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
App
|
amyloid beta precursor protein
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of APP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Araf
|
A-Raf proto-oncogene, serine/threonine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ARAF mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611
|
|
| G
|
Atm
|
ATM serine/threonine kinase
|
increases response to substance
|
ISO
|
ATM gene mutant form results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:15010311 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
|
|
| G
|
Atp1b3
|
ATPase Na+/K+ transporting subunit beta 3
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ATP1B3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304 Ensembl chr 8:65,253,361...65,254,304
|
|
| G
|
Atr
|
ATR serine/threonine kinase
|
multiple interactions
|
ISO
|
ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Axl
|
Axl receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of AXL mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
decreases expression decreases phosphorylation multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BAD mRNA Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of BAD protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAD mRNA]
|
CTD |
PMID:17828454 PMID:20434464 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bag1
|
BAG cochaperone 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BAG1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161
|
|
| G
|
Bak1
|
BCL2-antagonist/killer 1
|
multiple interactions
|
ISO
|
BAK1 protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib]
|
CTD |
PMID:18376143 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions decreases expression
|
EXP ISO
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BAX protein; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] Methylnitronitrosoguanidine results in decreased expression of BAX mRNA; Methylnitronitrosoguanidine results in decreased expression of BAX protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BAX protein] BAX protein results in increased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib]
|
CTD |
PMID:16030430 PMID:18376143 PMID:20434464 PMID:35103375 |
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcat2
|
branched chain amino acid transaminase 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BCAT2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of BCL2 protein Methylnitronitrosoguanidine results in increased expression of BCL2 protein weifuchun affects the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA; Methylnitronitrosoguanidine results in increased expression of BCL2 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein] [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2 protein]
|
CTD |
PMID:16019050 PMID:16030430 PMID:20434464 PMID:35103375 PMID:36403744 |
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions increases expression
|
ISO
|
BCL2L1 protein results in decreased susceptibility to [Methylnitronitrosoguanidine co-treated with veliparib] Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BCL2L1 mRNA]
|
CTD |
PMID:18376143 PMID:20434464 |
|
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
|
|
| G
|
Bcl2l11
|
Bcl2-like 11
|
multiple interactions
|
EXP
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]
|
CTD |
PMID:16030430 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
|
|
| G
|
Bdnf
|
brain-derived neurotrophic factor
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of BDNF mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
|
Bgn
|
biglycan
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of BGN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
|
|
| G
|
Bid
|
BH3 interacting domain death agonist
|
multiple interactions decreases expression
|
ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of BID mRNA]
|
CTD |
PMID:20434464 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
| G
|
Birc2
|
baculoviral IAP repeat-containing 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BIRC2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
|
|
| G
|
Blvrb
|
biliverdin reductase B
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of BLVRB mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
|
|
| G
|
Bmp4
|
bone morphogenetic protein 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BMP4 mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172
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| G
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Brca1
|
BRCA1, DNA repair associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BRCA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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| G
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Brca2
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BRCA2, DNA repair associated
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of BRCA2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
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| G
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Bsg
|
basigin
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multiple interactions increases expression
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of BSG mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005
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|
| G
|
Btg2
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BTG anti-proliferation factor 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of BTG2 protein
|
CTD |
PMID:24821435 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
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|
| G
|
C1qb
|
complement C1q B chain
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of C1QB mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
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| G
|
C1s
|
complement C1s
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of C1S mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
|
|
| G
|
Calm1
|
calmodulin 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CALM1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381
|
|
| G
|
Casp3
|
caspase 3
|
increases activity decreases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased activity of CASP3 protein Methylnitronitrosoguanidine results in decreased expression of CASP3 protein Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA; Methylnitronitrosoguanidine results in decreased expression of CASP3 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride promotes the reaction [Methylnitronitrosoguanidine results in increased activity of CASP3 protein] [Methylnitronitrosoguanidine co-treated with N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride] results in increased activity of CASP3 protein; [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP3 protein]
|
CTD |
PMID:15589979 PMID:16019050 PMID:16030430 PMID:17428624 PMID:20434464 PMID:24476502 PMID:35103375 More...
|
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
|
|
| G
|
Casp4
|
caspase 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CASP4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
|
|
| G
|
Casp8
|
caspase 8
|
multiple interactions
|
EXP
|
[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein; [S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
|
CTD |
PMID:16030430 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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|
| G
|
Casp9
|
caspase 9
|
increases activity decreases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased activity of CASP9 protein Methylnitronitrosoguanidine results in decreased expression of CASP9 protein corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CASP9 protein]
|
CTD |
PMID:15589979 PMID:16019050 PMID:20434464 PMID:35103375 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Cat
|
catalase
|
multiple interactions decreases activity
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in decreased activity of CAT protein]
|
CTD |
PMID:35103375 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cbx5
|
chromobox 5
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CBX5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118
|
|
| G
|
Ccna1
|
cyclin A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300
|
|
| G
|
Ccnb1
|
cyclin B1
|
multiple interactions decreases expression increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCNB1 mRNA] Methylnitronitrosoguanidine results in decreased expression of CCNB1 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCNB1 mRNA
|
CTD |
PMID:11516527 PMID:12135628 PMID:19851710 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCND1 protein Methylnitronitrosoguanidine results in increased expression of CCND1 mRNA; Methylnitronitrosoguanidine results in increased expression of CCND1 protein
|
CTD |
PMID:12135628 PMID:19851710 PMID:21628965 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccng1
|
cyclin G1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNG1 mRNA
|
CTD |
PMID:11516527 |
|
NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
|
|
| G
|
Ccnh
|
cyclin H
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CCNH mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860
|
|
| G
|
Cct2
|
chaperonin containing TCP1 subunit 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CCT2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
|
|
| G
|
Cd14
|
CD14 molecule
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of CD14 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CD14 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
|
|
| G
|
Cd59b
|
CD59b molecule
|
increases mutagenesis
|
ISO
|
Methylnitronitrosoguanidine results in increased mutagenesis of CD59 protein
|
CTD |
PMID:17045307 |
|
NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310
|
|
| G
|
Cd9
|
CD9 molecule
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CD9 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444
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|
| G
|
Cdh1
|
cadherin 1
|
multiple interactions decreases expression
|
EXP ISO
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein] Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA; Methylnitronitrosoguanidine results in decreased expression of CDH1 protein
|
CTD |
PMID:28428697 PMID:38184286 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
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|
| G
|
Cdh2
|
cadherin 2
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein] Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA; Methylnitronitrosoguanidine results in increased expression of CDH2 protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]
|
CTD |
PMID:38184286 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh8
|
cadherin 8
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CDH8 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr19:5,494,552...5,901,950
Ensembl chr19:5,500,221...5,902,627
|
|
| G
|
Cdk4
|
cyclin-dependent kinase 4
|
increases expression multiple interactions
|
EXP ISO
|
Methylnitronitrosoguanidine results in increased expression of CDK4 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDK4 protein] [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein
|
CTD |
PMID:12135628 PMID:21628965 PMID:36403744 |
|
NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
|
|
| G
|
Cdk5
|
cyclin-dependent kinase 5
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CDK5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
decreases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of CDKN1A mRNA Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein]
|
CTD |
PMID:12634122 PMID:19851710 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cdkn1b
|
cyclin-dependent kinase inhibitor 1B
|
decreases expression multiple interactions increases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDKN1B protein]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1B mRNA]
|
CTD |
PMID:11516527 PMID:12135628 |
|
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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|
| G
|
Cep43
|
centrosomal protein 43
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of CEP43 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:55,080,983...55,111,509
Ensembl chr 1:55,082,712...55,111,509
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|
| G
|
Chek1
|
checkpoint kinase 1
|
multiple interactions
|
ISO
|
CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
ISO
|
CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]
|
CTD |
PMID:26921499 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Ckb
|
creatine kinase B
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CKB mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
|
|
| G
|
Clta
|
clathrin, light chain A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CLTA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL1A2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col6a1
|
collagen type VI alpha 1 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL6A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
|
|
| G
|
Col8a1
|
collagen type VIII alpha 1 chain
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of COL8A1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229
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|
| G
|
Cox6a1
|
cytochrome c oxidase subunit 6A1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr12:46,922,709...46,925,762
Ensembl chr12:46,912,648...46,925,768
|
|
| G
|
Cox8a
|
cytochrome c oxidase subunit 8A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:213,831,302...213,833,623
Ensembl chr 1:213,831,298...213,833,623
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
multiple interactions increases expression
|
EXP
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CTNNB1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Ctsb
|
cathepsin B
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of CTSB mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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|
| G
|
Ctsl
|
cathepsin L
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CTSL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of CXCL12 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
|
|
| G
|
Cxcr4
|
C-X-C motif chemokine receptor 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CXCR4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
|
|
| G
|
Cyb561d2
|
cytochrome b561 family, member D2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of CYB561D2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:117,091,844...117,094,434
Ensembl chr 8:117,091,845...117,094,366
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
multiple interactions decreases expression
|
ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CYCS protein] Methylnitronitrosoguanidine results in decreased expression of CYCS mRNA; Methylnitronitrosoguanidine results in decreased expression of CYCS protein
|
CTD |
PMID:20434464 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Dab2
|
DAB adaptor protein 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DAB2 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888
|
|
| G
|
Dcn
|
decorin
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of DCN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
|
|
| G
|
Deaf1
|
DEAF1 transcription factor
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of DEAF1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106
|
|
| G
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Dek
|
DEK proto-oncogene
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DEK mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
|
|
| G
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Dlg1
|
discs large MAGUK scaffold protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of DLG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797
|
|
| G
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Dstn
|
destrin, actin depolymerizing factor
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of DSTN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769
|
|
| G
|
Dut
|
deoxyuridine triphosphatase
|
affects localization increases secretion
|
ISO
|
Methylnitronitrosoguanidine affects the localization of DUT protein Methylnitronitrosoguanidine results in increased secretion of DUT protein
|
CTD |
PMID:21658424 |
|
NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956
|
|
| G
|
E2f1
|
E2F transcription factor 1
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of E2F1 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
|
|
| G
|
E2f3
|
E2F transcription factor 3
|
multiple interactions
|
ISO
|
[[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of E2F3 protein]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]
|
CTD |
PMID:26921499 |
|
NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725
|
|
| G
|
Egf
|
epidermal growth factor
|
affects activity multiple interactions
|
ISO
|
Methylnitronitrosoguanidine affects the activity of EGF protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]; Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:15708576 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
affects localization multiple interactions
|
ISO
|
Methylnitronitrosoguanidine affects the localization of EGFR protein Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:15708576 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Egr1
|
early growth response 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EGR1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
| G
|
Eif1
|
eukaryotic translation initiation factor 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654 Ensembl chr10:25,895,968...25,896,654
|
|
| G
|
Eif3e
|
eukaryotic translation initiation factor 3 subunit E
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EIF3E mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785
|
|
| G
|
Eif5
|
eukaryotic translation initiation factor 5
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of EIF5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821
|
|
| G
|
Eif5a
|
eukaryotic translation initiation factor 5A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EIF5A mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
|
|
| G
|
Elk3
|
ETS transcription factor ELK3
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ELK3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:29,655,676...29,718,163
Ensembl chr 7:29,655,693...29,691,661
|
|
| G
|
Emp1
|
epithelial membrane protein 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EMP1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365
|
|
| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ENPP2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
|
|
| G
|
Epcam
|
epithelial cell adhesion molecule
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EPCAM mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
|
|
| G
|
Epha1
|
Eph receptor A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of EPHA1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474
|
|
| G
|
Ephb3
|
Eph receptor B3
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of EPHB3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775
|
|
| G
|
Eps8
|
EGFR pathway substrate 8, signaling adaptor
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of EPS8 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160
|
|
| G
|
Erbb2
|
erb-b2 receptor tyrosine kinase 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ERBB2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481
|
|
| G
|
Erbb4
|
erb-b2 receptor tyrosine kinase 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ERBB4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772
|
|
| G
|
Esr2
|
estrogen receptor 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ESR2 mRNA; Methylnitronitrosoguanidine results in increased expression of ESR2 protein
|
CTD |
PMID:21628965 PMID:22330348 |
|
NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
|
|
| G
|
Ets1
|
ETS proto-oncogene 1, transcription factor
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of ETS1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
|
|
| G
|
Faslg
|
Fas ligand
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FASLG protein
|
CTD |
PMID:24821435 |
|
NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503
|
|
| G
|
Fasn
|
fatty acid synthase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FASN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
|
|
| G
|
Fau
|
FAU ubiquitin like and ribosomal protein S30 fusion
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of FAU mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:212,779,473...212,781,026 Ensembl chr 1:212,779,473...212,781,026
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|
| G
|
Fcer1a
|
Fc epsilon receptor Ia
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FCER1A mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:88,218,427...88,224,723
Ensembl chr13:88,218,420...88,224,681
|
|
| G
|
Fcgr2a
|
Fc gamma receptor 2A
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FCGR3 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394 Ensembl chr13:85,855,437...85,864,394
|
|
| G
|
Fcgrt
|
Fc gamma receptor and transporter
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FCGRT mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:104,710,902...104,720,685
Ensembl chr 1:104,710,909...104,720,532
|
|
| G
|
Fes
|
FES proto-oncogene, tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FES mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181
|
|
| G
|
Fgf10
|
fibroblast growth factor 10
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FGF10 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980
|
|
| G
|
Flt1
|
Fms related receptor tyrosine kinase 1
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of FLT1 mRNA]
|
CTD |
PMID:20434464 |
|
NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750
|
|
| G
|
Folr1
|
folate receptor alpha
|
increases methylation
|
ISO
|
Methylnitronitrosoguanidine results in increased methylation of FOLR1 promoter
|
CTD |
PMID:29644877 |
|
NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
|
|
| G
|
Fosl1
|
FOS like 1, AP-1 transcription factor subunit
|
decreases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of FOSL1 mRNA Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:12634122 PMID:26921499 |
|
NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391
|
|
| G
|
Fst
|
follistatin
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of FST mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491
|
|
| G
|
Fstl1
|
follistatin-like 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of FSTL1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126
|
|
| G
|
Fyn
|
FYN proto-oncogene, Src family tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of FYN mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479
|
|
| G
|
Gadd45a
|
growth arrest and DNA-damage-inducible, alpha
|
decreases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of GADD45A mRNA]
|
CTD |
PMID:19851710 |
|
NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807
|
|
| G
|
Gcgr
|
glucagon receptor
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of GCGR mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr10:106,306,803...106,314,970
Ensembl chr10:106,306,559...106,314,969
|
|
| G
|
Gdf15
|
growth differentiation factor 15
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022
|
|
| G
|
Gja1
|
gap junction protein, alpha 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689
|
|
| G
|
Gjb2
|
gap junction protein, beta 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of GJB2 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877
|
|
| G
|
Gli1
|
GLI family zinc finger 1
|
increases expression
|
EXP
|
MNNG increases expression of Gli1 mRNA in rat stomach
|
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540
|
|
| G
|
Gpc4
|
glypican 4
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GPC4 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057
|
|
| G
|
Gss
|
glutathione synthetase
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of GSS mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306
|
|
| G
|
Gstm2
|
glutathione S-transferase mu 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of GSTM2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:198,312,179...198,316,962
|
|
| G
|
Gsto1
|
glutathione S-transferase omega 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTO1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167
|
|
| G
|
Gstp1
|
glutathione S-transferase pi 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of GSTP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
|
|
| G
|
Gtf2i
|
general transcription factor II I
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]
|
CTD |
PMID:26921499 |
|
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
|
|
| G
|
Gzmf
|
granzyme F
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of GZMG mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:33,975,543...33,997,505
Ensembl chr15:33,977,505...33,997,572
|
|
| G
|
H2ax
|
H2A.X variant histone
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; E2F3 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]
|
CTD |
PMID:26921499 PMID:27233451 PMID:38563870 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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|
| G
|
H4c14
|
H4 clustered histone 14
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of H4C2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:186,520,468...186,520,863
Ensembl chr 4:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938 Ensembl chr17:171,403,627...171,403,938
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|
| G
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Hba-a2
|
hemoglobin alpha, adult chain 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HBA1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
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|
| G
|
Hes1
|
hes family bHLH transcription factor 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HES1 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HES1 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
|
|
| G
|
Hes6
|
hes family bHLH transcription factor 6
|
multiple interactions increases expression
|
EXP
|
weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HES6 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096
|
|
| G
|
Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA; Methylnitronitrosoguanidine results in increased expression of HIF1A protein corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A mRNA]; weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HIF1A protein]
|
CTD |
PMID:35103375 PMID:36403744 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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|
| G
|
Hmgb1
|
high mobility group box 1
|
increases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of HMGB1 mRNA]
|
CTD |
PMID:12634122 PMID:35103375 |
|
NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327 Ensembl chr12:39,039,050...39,041,327
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|
| G
|
Hmgb2
|
high mobility group box 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of HMGB2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hpgd
|
15-hydroxyprostaglandin dehydrogenase
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of HPGD mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831
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|
| G
|
Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of HPRT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Hras
|
HRas proto-oncogene, GTPase
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased activity of HRAS protein]
|
CTD |
PMID:15708576 |
|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
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|
| G
|
Hsp90aa1
|
heat shock protein 90 alpha family class A member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AA1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499
|
|
| G
|
Hsp90ab1
|
heat shock protein 90 alpha family class B member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSP90AB1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926
|
|
| G
|
Hsp90b1
|
heat shock protein 90 beta family member 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of HSP90B1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293
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|
| G
|
Hspa1a
|
heat shock protein family A (Hsp70) member 1A
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of HSPA1A mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
|
|
| G
|
Hspd1
|
heat shock protein family D (Hsp60) member 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of HSPD1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
|
|
| G
|
Icam1
|
intercellular adhesion molecule 1
|
decreases response to substance multiple interactions increases expression
|
ISO
|
ICAM1 protein results in decreased susceptibility to Methylnitronitrosoguanidine prolinedithiocarbamate inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of ICAM1 protein] Methylnitronitrosoguanidine results in increased expression of ICAM1 mRNA; Methylnitronitrosoguanidine results in increased expression of ICAM1 protein
|
CTD |
PMID:22001597 |
|
NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
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|
| G
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Id1
|
inhibitor of DNA binding 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ID1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685
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|
| G
|
Ier3
|
immediate early response 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IER3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
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|
| G
|
Ifitm1
|
interferon induced transmembrane protein 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of IFITM1 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776
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|
| G
|
Ifrd1
|
interferon-related developmental regulator 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of IFRD1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
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|
| G
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Igkc
|
immunoglobulin kappa constant
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of IGKC mRNA
|
CTD |
PMID:15120970 |
|
|
|
| G
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Igsf6
|
immunoglobulin superfamily, member 6
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of IGSF6 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245
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|
| G
|
Ikbkb
|
inhibitor of nuclear factor kappa B kinase subunit beta
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein]
|
CTD |
PMID:19851710 |
|
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
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|
| G
|
Il1b
|
interleukin 1 beta
|
increases secretion multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased secretion of IL1B protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL1B protein]
|
CTD |
PMID:38184286 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il6
|
interleukin 6
|
multiple interactions increases secretion increases expression
|
ISO EXP
|
weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein] weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IL6 protein]
|
CTD |
PMID:36403744 PMID:38184286 |
|
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
|
|
| G
|
Irak1
|
interleukin-1 receptor-associated kinase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of IRAK1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825
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|
| G
|
Itgb4
|
integrin subunit beta 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of ITGB4 mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932
|
|
| G
|
Jmjd6
|
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JMJD6 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:102,539,935...102,545,986
Ensembl chr10:102,539,894...102,545,986
|
|
| G
|
Jpt1
|
Jupiter microtubule associated homolog 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of JPT1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469
|
|
| G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
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|
| G
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Kctd12
|
potassium channel tetramerization domain containing 12
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of KCTD12 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539
|
|
| G
|
Kdm8
|
lysine demethylase 8
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]
|
CTD |
PMID:26025680 |
|
NCBI chr 1:189,444,527...189,459,507
Ensembl chr 1:189,444,555...189,459,491
|
|
| G
|
Kit
|
KIT proto-oncogene receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of KIT mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812
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|
| G
|
Kitlg
|
KIT ligand
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of KITLG mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
|
|
| G
|
Klf10
|
KLF transcription factor 10
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of KLF10 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948
|
|
| G
|
Klf7
|
KLF transcription factor 7
|
multiple interactions increases expression
|
ISO
|
KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KLF7 mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KLF7 protein] Methylnitronitrosoguanidine results in increased expression of KLF7 mRNA; Methylnitronitrosoguanidine results in increased expression of KLF7 protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in decreased expression of CDH1 mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of CDH2 mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased phosphorylation of RELA protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL1B protein]; KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased secretion of IL6 protein]
|
CTD |
PMID:38184286 |
|
NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:72,933,136...73,020,056
|
|
| G
|
Kras
|
KRAS proto-oncogene, GTPase
|
multiple interactions increases expression
|
EXP
|
geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of KRAS mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
|
|
| G
|
Krt17
|
keratin 17
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of KRT17 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787
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|
| G
|
Ldha
|
lactate dehydrogenase A
|
multiple interactions increases expression
|
EXP
|
corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of LDHA mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
|
|
| G
|
Lgals3
|
galectin 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Lgals8
|
galectin 8
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of LGALS8 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482
|
|
| G
|
Lig1
|
DNA ligase 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of LIG1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708
|
|
| G
|
Lipa
|
lipase A, lysosomal acid type
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of LIP1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
|
|
| G
|
Lox
|
lysyl oxidase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810
|
|
| G
|
Lpl
|
lipoprotein lipase
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LPL mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
|
|
| G
|
Map2k1
|
mitogen activated protein kinase kinase 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MAP2K1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
|
|
| G
|
Map3k12
|
mitogen activated protein kinase kinase kinase 12
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MAP3K12 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
multiple interactions decreases phosphorylation
|
ISO
|
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK1 protein]]
|
CTD |
PMID:17828454 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
increases phosphorylation
|
ISO
|
Methylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein
|
CTD |
PMID:22001597 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
multiple interactions decreases phosphorylation
|
ISO
|
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased phosphorylation of MAPK3 protein]]
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CTD |
PMID:17828454 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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| G
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Mapk4
|
mitogen-activated protein kinase 4
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of MAPK4 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr18:69,788,058...69,937,524
Ensembl chr18:69,788,060...69,837,037
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| G
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Mapk8
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mitogen-activated protein kinase 8
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increases phosphorylation
|
ISO
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Methylnitronitrosoguanidine results in increased phosphorylation of MAPK8 protein
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CTD |
PMID:22001597 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
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| G
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Mapk9
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mitogen-activated protein kinase 9
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of MAPK9 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
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| G
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Marcks
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myristoylated alanine rich protein kinase C substrate
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MARCKS mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA
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CTD |
PMID:19840844 |
|
NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
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| G
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Max
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MYC associated factor X
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increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of MAX mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:101,369,988...101,395,549
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| G
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Mcam
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melanoma cell adhesion molecule
|
increases expression
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ISO
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Methylnitronitrosoguanidine results in increased expression of MCAM mRNA
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CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406
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| G
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Mcm2
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minichromosome maintenance complex component 2
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decreases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MCM2 mRNA [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM2 mRNA
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CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094
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| G
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Mcm4
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minichromosome maintenance complex component 4
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MCM4 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536
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| G
|
Mcm6
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minichromosome maintenance complex component 6
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MCM6 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
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| G
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Mcpt1
|
mast cell protease 1
|
increases expression
|
EXP
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Methylnitronitrosoguanidine results in increased expression of MCPT1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr15:33,841,606...33,844,174
Ensembl chr15:33,841,606...33,844,174
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| G
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Mdm2
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MDM2 proto-oncogene
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increases expression multiple interactions
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ISO
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Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein]
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CTD |
PMID:12135628 PMID:12634122 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
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| G
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Mecom
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MDS1 and EVI1 complex locus
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of MECOM mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:114,837,815...115,393,052
Ensembl chr 2:114,837,840...115,393,038
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| G
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Met
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MET proto-oncogene, receptor tyrosine kinase
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MET mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
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| G
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Mgmt
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O-6-methylguanine-DNA methyltransferase
|
decreases response to substance
|
ISO
|
MGMT protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:1727384 PMID:15010311 PMID:16043385 |
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
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| G
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Mgst2
|
microsomal glutathione S-transferase 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MGST2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661
|
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| G
|
Mgst3
|
microsomal glutathione S-transferase 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MGST3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575
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| G
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Mir21
|
microRNA 21
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MIR21 mRNA
|
CTD |
PMID:24821435 |
|
NCBI chr10:71,902,600...71,902,691
|
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| G
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Mki67
|
marker of proliferation Ki-67
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MKI67 protein
|
CTD |
PMID:38563870 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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| G
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Mlh1
|
mutL homolog 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MLH1 protein
|
CTD |
PMID:17671175 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
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| G
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Mmp2
|
matrix metallopeptidase 2
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP2 protein [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MMP2 mRNA
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CTD |
PMID:19840844 PMID:20434464 |
|
NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
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|
| G
|
Mmp9
|
matrix metallopeptidase 9
|
multiple interactions increases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of MMP9 mRNA]; Methylnitronitrosoguanidine results in increased expression of and results in increased activity of MMP9 protein
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CTD |
PMID:20434464 |
|
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
|
|
| G
|
Mpg
|
N-methylpurine-DNA glycosylase
|
increases response to substance
|
ISO
|
MPG protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:15299078 |
|
NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052
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| G
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Mpp1
|
MAGUK p55 scaffold protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of MPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA
|
CTD |
PMID:19840844 |
|
|
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| G
|
Msh2
|
mutS homolog 2
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increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MSH2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
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| G
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Mst1
|
macrophage stimulating 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MST1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015
|
|
| G
|
Mt1a
|
metallothionein 1A
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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|
| G
|
Mthfr
|
methylenetetrahydrofolate reductase
|
increases methylation
|
ISO
|
Methylnitronitrosoguanidine results in increased methylation of MTHFR promoter
|
CTD |
PMID:29644877 |
|
NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105
|
|
| G
|
Mutyh
|
mutY DNA glycosylase
|
multiple interactions
|
ISO
|
MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein]
|
CTD |
PMID:26954031 |
|
NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:135,517,695...135,522,776
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| G
|
Mx2
|
MX dynamin like GTPase 2
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of MX2 mRNA
|
CTD |
PMID:12082013 |
|
NCBI chr11:50,375,101...50,399,373
Ensembl chr11:50,375,191...50,402,478
|
|
| G
|
Mybl1
|
MYB proto-oncogene like 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYBL1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYC protein Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MYC protein]
|
CTD |
PMID:12135628 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Myl2
|
myosin light chain 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYL2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149
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|
| G
|
Myl9
|
myosin light chain 9
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of MYL9 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410
|
|
| G
|
Mylk
|
myosin light chain kinase
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of MYLK mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659
|
|
| G
|
Nbl1
|
NBL1, DAN family BMP antagonist
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of NBL1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:156,601,986...156,613,186
|
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| G
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Nfkb1
|
nuclear factor kappa B subunit 1
|
multiple interactions increases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKB1 protein] Methylnitronitrosoguanidine results in increased expression of NFKB1 mRNA; Methylnitronitrosoguanidine results in increased expression of NFKB1 protein
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CTD |
PMID:19851710 PMID:38184286 |
|
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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| G
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Nfkbia
|
NFKB inhibitor alpha
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multiple interactions increases expression decreases expression
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of NFKBIA protein modified form] Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased degradation of NFKBIA protein Methylnitronitrosoguanidine results in decreased expression of NFKBIA mRNA; Methylnitronitrosoguanidine results in decreased expression of NFKBIA protein
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CTD |
PMID:19851710 PMID:22001597 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
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| G
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Nfya
|
nuclear transcription factor Y subunit alpha
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504
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| G
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Nfyb
|
nuclear transcription factor Y subunit beta
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]
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CTD |
PMID:26921499 |
|
NCBI chr 7:22,852,543...22,868,116
Ensembl chr 7:22,852,546...22,882,294
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| G
|
Nfyc
|
nuclear transcription factor Y subunit gamma
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 5:139,622,020...139,690,545
Ensembl chr 5:139,622,020...139,679,884
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|
| G
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Nnmt
|
nicotinamide N-methyltransferase
|
increases activity
|
EXP
|
Methylnitronitrosoguanidine results in increased activity of NNMT protein
|
CTD |
PMID:6652621 |
|
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
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|
| G
|
Nrp1
|
neuropilin 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of NRP1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702
|
|
| G
|
Odc1
|
ornithine decarboxylase 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of ODC1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146
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|
| G
|
Pa2g4
|
proliferation-associated 2G4
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PA2G4 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802
|
|
| G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
multiple interactions affects response to substance
|
ISO
|
[Hydrolyzable Tannins results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [nobotanin B results in decreased activity of PARG protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; benzamide inhibits the reaction [PARG affects the susceptibility to Methylnitronitrosoguanidine]
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CTD |
PMID:11593040 PMID:15591342 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
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|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
multiple interactions increases expression increases response to substance affects cleavage increases activity
|
ISO
|
[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine; [Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD; benzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]; Hydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]; MUTYH protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PARP1 protein] PARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:11593040 PMID:20434464 PMID:22001597 PMID:26954031 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
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|
| G
|
Pcbp2
|
poly(rC) binding protein 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCBP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412
|
|
| G
|
Pcdh7
|
protocadherin 7
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PCDH7 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665
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|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA Methylnitronitrosoguanidine results in increased expression of PCNA mRNA; Methylnitronitrosoguanidine results in increased expression of PCNA protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PCNA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PCNA mRNA]; Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein] Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]; geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PCNA protein]
|
CTD |
PMID:11516527 PMID:12135628 PMID:12634122 PMID:19840844 PMID:19851710 PMID:22330348 PMID:28428697 More...
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|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pdgfb
|
platelet derived growth factor subunit B
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PDGFB mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
|
|
| G
|
Pdgfra
|
platelet derived growth factor receptor alpha
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PDGFRA mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516
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|
| G
|
Pdia3
|
protein disulfide isomerase family A, member 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PDIA3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327
|
|
| G
|
Pea15
|
proliferation and apoptosis adaptor protein 15
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PEA15 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859
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|
| G
|
Pgk1
|
phosphoglycerate kinase 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PGK1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959
|
|
| G
|
Pgr
|
progesterone receptor
|
decreases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of PGR protein geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PGR protein]
|
CTD |
PMID:28428697 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
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|
| G
|
Pik3cg
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3CG mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509
|
|
| G
|
Pik3r1
|
phosphoinositide-3-kinase regulatory subunit 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of PIK3R1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347
|
|
| G
|
Plxna3
|
plexin A3
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PLXNA3 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr X:157,266,986...157,282,896
Ensembl chr X:157,267,107...157,282,891
|
|
| G
|
Podxl
|
podocalyxin-like
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PODXL mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PODXL mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789
|
|
| G
|
Postn
|
periostin
|
decreases expression
|
EXP
|
Methylnitronitrosoguanidine results in decreased expression of POSTN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300
|
|
| G
|
Ppp2r2a
|
protein phosphatase 2, regulatory subunit B, alpha
|
decreases response to substance
|
ISO
|
PPP2R2A protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr15:45,380,142...45,439,428
Ensembl chr15:45,379,683...45,439,405
|
|
| G
|
Ppp2r5c
|
protein phosphatase 2, regulatory subunit B', gamma
|
increases response to substance
|
ISO
|
PPP2R5C protein results in increased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr 6:135,282,947...135,419,591
Ensembl chr 6:135,324,067...135,419,597
|
|
| G
|
Ppp2r5e
|
protein phosphatase 2 regulatory subunit B', epsilon
|
decreases response to substance
|
ISO
|
PPP2R5E protein results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:25772433 |
|
NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573
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|
| G
|
Prkd1
|
protein kinase D1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PRKD1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509
|
|
| G
|
Pten
|
phosphatase and tensin homolog
|
decreases response to substance multiple interactions decreases expression
|
ISO EXP
|
PTEN protein results in decreased susceptibility to Methylnitronitrosoguanidine geraniol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of PTEN protein]
|
CTD |
PMID:20530668 PMID:28428697 |
|
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
|
|
| G
|
Ptn
|
pleiotrophin
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of PTN mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482
|
|
| G
|
Ptp4a1
|
protein tyrosine phosphatase 4A1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of PTP4A1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176
|
|
| G
|
Ptpra
|
protein tyrosine phosphatase, receptor type, A
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRA mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:138,103,261...138,212,835
Ensembl chr 3:138,098,110...138,213,126
|
|
| G
|
Ptprg
|
protein tyrosine phosphatase, receptor type, G
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRG mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr15:15,298,669...15,982,581
Ensembl chr15:15,302,133...15,982,668
|
|
| G
|
Ptprs
|
protein tyrosine phosphatase, receptor type, S
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of PTPRS mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 9:1,332,558...1,394,161
Ensembl chr 9:1,332,559...1,394,093
|
|
| G
|
Pttg1
|
PTTG1 regulator of sister chromatid separation, securin
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of PTTG1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309
|
|
| G
|
Pura
|
purine rich element binding protein A
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr18:28,159,103...28,179,539
Ensembl chr18:28,125,126...28,211,111
|
|
| G
|
Racgap1
|
Rac GTPase-activating protein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RACGAP1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738
|
|
| G
|
Rad21
|
RAD21 cohesin complex component
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RAD21 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657
|
|
| G
|
Rad23a
|
RAD23 homolog A, nucleotide excision repair protein
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of RAD23A mRNA
|
CTD |
PMID:12634122 PMID:12773770 |
|
NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543
|
|
| G
|
Rbbp5
|
RB binding protein 5, histone lysine methyltransferase complex subunit
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RBBP5 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr13:46,464,389...46,494,244
Ensembl chr13:46,464,389...46,491,238
|
|
| G
|
Rbm6
|
RNA binding motif protein 6
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RBM6 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 8:117,327,607...117,431,397
Ensembl chr 8:117,331,325...117,431,397
|
|
| G
|
Reck
|
reversion-inducing-cysteine-rich protein with kazal motifs
|
multiple interactions decreases expression
|
EXP
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of RECK protein] Methylnitronitrosoguanidine results in decreased expression of RECK mRNA; Methylnitronitrosoguanidine results in decreased expression of RECK protein
|
CTD |
PMID:20434464 |
|
NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions increases expression increases phosphorylation
|
EXP ISO
|
Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein] KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RELA protein] Methylnitronitrosoguanidine results in increased phosphorylation of RELA protein KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased phosphorylation of RELA protein] Methylnitronitrosoguanidine results in increased expression of RELA mRNA; Methylnitronitrosoguanidine results in increased expression of RELA protein
|
CTD |
PMID:19851710 PMID:38184286 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Reln
|
reelin
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of RELN mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162
|
|
| G
|
Rgs18
|
regulator of G-protein signaling 18
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of RGS18 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr13:59,043,431...59,066,342
Ensembl chr13:59,043,431...59,066,342
|
|
| G
|
Ros1
|
ROS proto-oncogene 1 , receptor tyrosine kinase
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of ROS1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,975,329...32,126,547
|
|
| G
|
Rpl7
|
ribosomal protein L7
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPL7 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451
|
|
| G
|
Rps11
|
ribosomal protein S11
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:104,742,155...104,744,337
|
|
| G
|
Rps20
|
ribosomal protein S20
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of RPS20 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621 Ensembl chr 9:42,839,965...43,095,621 Ensembl chr 5:42,839,965...43,095,621
|
|
| G
|
Rpsa
|
ribosomal protein SA
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RPSA mRNA
|
CTD |
PMID:12773770 |
|
NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737
|
|
| G
|
Rrm2
|
ribonucleotide reductase regulatory subunit M2
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]; [Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; CHEK1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; CHIR-124 inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [[FOSL1 protein binds to JUNB protein] which results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [DP1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [FOSL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [GTF2I protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [IFI16 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYB protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [NFYC protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [PURA protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [PURA protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2 protein; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein binds to RRM2 promoter]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine promotes the reaction [E2F3 protein results in increased expression of RRM2 mRNA]]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA]; NFYB protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2 protein]; RRM2 protein inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form]
|
CTD |
PMID:26921499 |
|
NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370
|
|
| G
|
Rrm2b
|
ribonucleotide reductase regulatory TP53 inducible subunit M2B
|
increases expression multiple interactions affects expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein]; E2F1 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; E2F3 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B mRNA]; Methylnitronitrosoguanidine results in increased expression of and affects the localization of RRM2B protein; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] Methylnitronitrosoguanidine affects the expression of RRM2B mRNA
|
CTD |
PMID:21704725 PMID:26921499 |
|
NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:70,965,590...70,993,670
|
|
| G
|
RT1-Db1
|
RT1 class II, locus Db1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of HLA-DRB1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165
|
|
| G
|
Ruvbl1
|
RuvB-like AAA ATPase 1
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [RUVBL1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 4:122,489,754...122,524,666
Ensembl chr 4:122,489,680...122,524,665
|
|
| G
|
Sec61g
|
Sec61 translocon subunit gamma
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr14:95,113,083...95,119,458
Ensembl chr 9:48,798,504...48,798,710 Ensembl chr14:48,798,504...48,798,710
|
|
| G
|
Selenop
|
selenoprotein P
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of SELENOP mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
|
|
| G
|
Serpine1
|
serpin family E member 1
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357
|
|
| G
|
Serping1
|
serpin family G member 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SERPING1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717
|
|
| G
|
Slc16a3
|
solute carrier family 16 member 3
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA corilagin inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SLC16A3 mRNA]
|
CTD |
PMID:35103375 |
|
NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903
|
|
| G
|
Smad2
|
SMAD family member 2
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SMAD2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388
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| G
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Smo
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smoothened, frizzled class receptor
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increases expression
|
EXP
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MNNG increases expression of Smo mRNA in rat stomach
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RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281
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| G
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Snai1
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snail family transcriptional repressor 1
|
increases expression multiple interactions
|
ISO
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Methylnitronitrosoguanidine results in increased expression of SNAI1 protein KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of SNAI1 protein]
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CTD |
PMID:38184286 |
|
NCBI chr 3:176,667,476...176,671,965
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| G
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Snora62
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small nucleolar RNA, H/ACA box 62
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increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of SNORA62 mRNA
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CTD |
PMID:12773770 |
|
NCBI chr 8:128,731,591...128,731,739
Ensembl chr 8:128,731,591...128,731,739
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| G
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Snrpn
|
small nuclear ribonucleoprotein polypeptide N
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of SNRPN mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 1:120,316,846...120,338,919
Ensembl chr 1:120,315,556...120,323,924
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| G
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Sparc
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secreted protein acidic and cysteine rich
|
decreases expression
|
ISO
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Methylnitronitrosoguanidine results in decreased expression of SPARC mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268
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| G
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Spink1
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serine peptidase inhibitor, Kazal type 1
|
increases expression
|
ISO
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Methylnitronitrosoguanidine results in increased expression of SPINK1 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545
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| G
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Spint2
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serine peptidase inhibitor, Kunitz type, 2
|
decreases expression increases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SPINT2 mRNA Methylnitronitrosoguanidine results in increased expression of SPINT2 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 1:93,685,637...93,708,091
Ensembl chr 1:93,685,641...93,708,091
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| G
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Spp1
|
secreted phosphoprotein 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SPP1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
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| G
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Sqle
|
squalene epoxidase
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increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of SQLE mRNA [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SQLE mRNA
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CTD |
PMID:12634122 PMID:19840844 |
|
NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050
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| G
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Srsf7
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serine and arginine rich splicing factor 7
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of SRSF7 mRNA
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CTD |
PMID:12634122 |
|
NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212
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| G
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Stk39
|
serine threonine kinase 39
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of STK39 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740
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| G
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Sufu
|
SUFU negative regulator of hedgehog signaling
|
decreases expression
|
EXP
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MNNG decreases expression of Sufu mRNA in rat stomach
|
RGD |
PMID:30537251 |
RGD:150520178 |
NCBI chr 1:255,199,108...255,296,983
Ensembl chr 1:255,199,164...255,296,981
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| G
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Sumo2
|
small ubiquitin-like modifier 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SUMO2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr10:101,270,899...101,283,458
Ensembl chr10:101,270,900...101,283,938 Ensembl chr 5:101,270,900...101,283,938
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| G
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Syn1
|
synapsin I
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of SYN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr X:3,725,745...3,780,940
Ensembl chr X:3,725,714...3,780,938
|
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| G
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Tbrg4
|
transforming growth factor beta regulator 4
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TBRG4 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:85,696,738...85,704,691
Ensembl chr14:85,695,893...85,704,659
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| G
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Tgfb1
|
transforming growth factor, beta 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA geraniol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TGFB1 mRNA]
|
CTD |
PMID:28428697 |
|
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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| G
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Thbs1
|
thrombospondin 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
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| G
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Thbs2
|
thrombospondin 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918
|
|
| G
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Tiam1
|
TIAM Rac1 associated GEF 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TIAM1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr11:42,517,527...42,866,280
Ensembl chr11:42,517,528...42,646,075
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|
| G
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Timp2
|
TIMP metallopeptidase inhibitor 2
|
decreases expression multiple interactions
|
EXP ISO
|
Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA; Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TIMP2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 mRNA]; Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TIMP2 protein]
|
CTD |
PMID:19840844 PMID:20434464 |
|
NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
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|
| G
|
Tlr2
|
toll-like receptor 2
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of TLR2 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TLR2 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
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|
| G
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Tlr4
|
toll-like receptor 4
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of TLR4 mRNA
|
CTD |
PMID:15120970 |
|
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
|
|
| G
|
Tmsb4x
|
thymosin beta 4, X-linked
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TMSB4X mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr X:30,761,611...30,763,612
Ensembl chr X:30,761,612...30,763,613
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|
| G
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Tnc
|
tenascin C
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TNC mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131
|
|
| G
|
Tnf
|
tumor necrosis factor
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increases expression multiple interactions increases secretion
|
EXP ISO
|
Methylnitronitrosoguanidine results in increased expression of TNF protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased secretion of TNF protein] weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TNF protein]
|
CTD |
PMID:36403744 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
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Tnfrsf25
|
TNF receptor superfamily member 25
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TNFRSF25 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:167,904,377...167,909,052
Ensembl chr 5:167,904,786...167,909,052
|
|
| G
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Top2a
|
DNA topoisomerase II alpha
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TOP2A mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
|
|
| G
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Tp53
|
tumor protein p53
|
increases expression multiple interactions decreases expression increases acetylation increases response to substance decreases response to substance
|
ISO EXP
|
Methylnitronitrosoguanidine results in increased expression of TP53 mRNA; Methylnitronitrosoguanidine results in increased expression of TP53 protein ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; CHEK2 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TP53 protein]; Methylnitronitrosoguanidine inhibits the reaction [TP53 protein binds to KDM8 protein]; TP53 protein mutant form inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of RRM2B protein] Methylnitronitrosoguanidine results in increased expression of TRP53 protein [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TRP53 mRNA; Cadmium Chloride inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TRP53 protein] Methylnitronitrosoguanidine results in decreased expression of TP53 protein Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of TP53 protein]; resveratrol inhibits the reaction [Methylnitronitrosoguanidine results in increased acetylation of TP53 protein] TP53 protein results in increased susceptibility to Methylnitronitrosoguanidine TP53 protein mutant form results in decreased susceptibility to Methylnitronitrosoguanidine
|
CTD |
PMID:9667752 PMID:11516527 PMID:12135628 PMID:12634122 PMID:15589979 PMID:17147953 PMID:19851710 PMID:26025680 PMID:26921499 More...
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|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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| G
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Tram1
|
translocation associated membrane protein 1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of TRAM1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 5:10,425,710...10,450,669
Ensembl chr 5:10,425,633...10,470,056
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|
| G
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Tsc22d1
|
TSC22 domain family, member 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of TSC22D1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322
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|
| G
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Ttc3
|
tetratricopeptide repeat domain 3
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of TTC3 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA
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CTD |
PMID:19840844 |
|
NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418
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| G
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Twist1
|
twist family bHLH transcription factor 1
|
multiple interactions increases expression
|
ISO
|
KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of TWIST1 protein]
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CTD |
PMID:38184286 |
|
NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965
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| G
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Txn1
|
thioredoxin 1
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of TXN1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
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|
| G
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Ubc
|
ubiquitin C
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275
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| G
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Ubd
|
ubiquitin D
|
increases expression
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of UBD mRNA
|
CTD |
PMID:12082013 |
|
NCBI chr20:1,390,734...1,392,685
Ensembl chr20:1,390,600...1,413,965
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|
| G
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Uchl1
|
ubiquitin C-terminal hydrolase L1
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of UCHL1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
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|
| G
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Ucp2
|
uncoupling protein 2
|
multiple interactions
|
ISO
|
[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of UCP2 mRNA
|
CTD |
PMID:19840844 |
|
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
|
|
| G
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Vcam1
|
vascular cell adhesion molecule 1
|
increases expression multiple interactions
|
EXP
|
Methylnitronitrosoguanidine results in increased expression of VCAM1 protein weifuchun inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VCAM1 protein]
|
CTD |
PMID:36403744 |
|
NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
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| G
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Vim
|
vimentin
|
increases expression multiple interactions
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of VIM mRNA; Methylnitronitrosoguanidine results in increased expression of VIM protein KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]]; KLF7 protein inhibits the reaction [MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein]]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]; MIR520F inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of VIM protein] KLF7 protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of VIM mRNA]
|
CTD |
PMID:12634122 PMID:12773770 PMID:38184286 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
|
|
| G
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Wars1
|
tryptophanyl-tRNA synthetase 1
|
decreases expression
|
ISO
|
Methylnitronitrosoguanidine results in decreased expression of WARS1 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
|
|
| G
|
Wnt2
|
Wnt family member 2
|
increases expression
|
ISO
|
Methylnitronitrosoguanidine results in increased expression of WNT2 mRNA
|
CTD |
PMID:12634122 |
|
NCBI chr 4:47,294,300...47,340,284
Ensembl chr 4:47,294,300...47,421,976
|
|
| G
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Yy1
|
YY1 transcription factor
|
multiple interactions
|
ISO
|
Methylnitronitrosoguanidine promotes the reaction [YY1 protein binds to RRM2 promoter]; Methylnitronitrosoguanidine promotes the reaction [YY1 protein results in increased expression of RRM2 mRNA]
|
CTD |
PMID:26921499 |
|
NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257
|
|
|
|
| G
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Abhd4
|
abhydrolase domain containing 4, N-acyl phospholipase B
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of ABHD4 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr15:31,674,090...31,686,051
Ensembl chr15:31,674,143...31,687,007
|
|
| G
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Acly
|
ATP citrate lyase
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ACLY mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631
|
|
| G
|
Actb
|
actin, beta
|
increases mutagenesis
|
EXP
|
Methylnitrosourea results in increased mutagenesis of ACTB gene
|
CTD |
PMID:10767621 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ADAMTS1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Afp
|
alpha-fetoprotein
|
decreases response to substance
|
EXP
|
AFP protein modified form results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:16322315 |
|
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
|
|
| G
|
Agtr1b
|
angiotensin II receptor, type 1b
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of AGTR1B mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 2:104,774,005...104,849,262
Ensembl chr 2:104,773,930...104,849,310
|
|
| G
|
Akr1b10
|
aldo-keto reductase family 1 member B10
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of AKR1B10 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
|
|
| G
|
Akr1b15
|
aldo-keto reductase family 1 member B15
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of AKR1B8 protein
|
CTD |
PMID:11565795 |
|
NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
|
|
| G
|
Akt1
|
AKT serine/threonine kinase 1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of AKT1 protein; [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of AKT1 protein; Methylnitrosourea results in increased phosphorylation of and results in increased activity of AKT1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of AKT1 protein]
|
CTD |
PMID:15581186 PMID:22465879 PMID:25164625 |
|
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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| G
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Akt2
|
AKT serine/threonine kinase 2
|
multiple interactions
|
EXP
|
[Hexachlorobenzene co-treated with Methylnitrosourea] results in increased phosphorylation of AKT2 protein
|
CTD |
PMID:22245120 |
|
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
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| G
|
Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of ALDH1A1 mRNA
|
CTD |
PMID:25922126 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
|
|
| G
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Angptl4
|
angiopoietin-like 4
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ANGPTL4 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
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|
| G
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Ap3s1
|
adaptor related protein complex 3 subunit sigma 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of AP3S1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr18:41,649,321...41,718,221
Ensembl chr18:41,648,796...41,767,641
|
|
| G
|
Apaf1
|
apoptotic peptidase activating factor 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of APAF1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
|
|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
increases response to substance
|
ISO
|
APC gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:12096346 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
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|
| G
|
Aqp1
|
aquaporin 1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of AQP1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504
|
|
| G
|
Areg
|
amphiregulin
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Estradiol] results in increased expression of AREG mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of AREG mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of AREG mRNA
|
CTD |
PMID:20732338 |
|
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641
|
|
| G
|
Asip
|
agouti signaling protein
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of A gene
|
CTD |
PMID:10517996 PMID:17174358 |
|
NCBI chr 3:163,933,768...164,021,377
Ensembl chr 3:164,015,903...164,021,378
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|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of ASNS mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Atf1
|
activating transcription factor 1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of ATF1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485
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|
| G
|
Atp6v1f
|
ATPase H+ transporting V1 subunit F
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of ATP6V1F gene
|
CTD |
PMID:16868089 |
|
NCBI chr 4:59,033,020...59,035,980
|
|
| G
|
Atr
|
ATR serine/threonine kinase
|
affects localization multiple interactions
|
ISO
|
Methylnitrosourea affects the localization of ATR protein MSH2 protein promotes the reaction [Methylnitrosourea affects the localization of ATR protein]
|
CTD |
PMID:21285353 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Aurka
|
aurora kinase A
|
multiple interactions decreases expression increases expression
|
EXP ISO
|
[Estrogens co-treated with Progesterone] inhibits the reaction [Methylnitrosourea results in increased expression of AURKA mRNA] Methylnitrosourea results in decreased expression of AURKA mRNA
|
CTD |
PMID:12124350 PMID:27233451 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
|
|
| G
|
Aurkb
|
aurora kinase B
|
decreases phosphorylation
|
ISO
|
Methylnitrosourea results in decreased phosphorylation of AURKB protein
|
CTD |
PMID:27233451 |
|
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
|
|
| G
|
Axin1
|
axin 1
|
decreases expression
|
EXP
|
N-methyl-N-nitrosourea decreases expression of Axin1 mRNA in colon
|
RGD |
PMID:28032729 |
RGD:150530464 |
NCBI chr10:15,667,894...15,720,092
Ensembl chr10:15,667,958...15,720,092
|
|
| G
|
B3galt1
|
Beta-1,3-galactosyltransferase 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of B3GALT1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 3:72,661,410...73,234,447
Ensembl chr 3:72,660,801...73,235,276
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAD mRNA
|
CTD |
PMID:20732338 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bax
|
BCL2 associated X, apoptosis regulator
|
multiple interactions increases expression
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased expression of BAX protein; [Methylnitrosourea co-treated with Estradiol] results in decreased expression of BAX mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of BAX mRNA; [Methylnitrosourea co-treated with Progesterone] results in decreased expression of BAX mRNA; FGF1 protein modified form inhibits the reaction [Methylnitrosourea results in increased expression of BAX protein]; Niacinamide inhibits the reaction [Methylnitrosourea results in increased expression of BAX protein] Methylnitrosourea results in increased expression of BAX mRNA; Methylnitrosourea results in increased expression of BAX protein
|
CTD |
PMID:16011256 PMID:16047940 PMID:16168987 PMID:20732338 PMID:22465879 PMID:28688903 More...
|
|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
|
|
| G
|
Bcl10
|
BCL10, immune signaling adaptor
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of BCL10 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
|
|
| G
|
Bcl2
|
BCL2, apoptosis regulator
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of BCL2 protein; [Methylnitrosourea co-treated with Estradiol] results in increased expression of BCL2 mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of BCL2 mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of BCL2 mRNA; FGF1 protein modified form inhibits the reaction [Methylnitrosourea results in decreased expression of BCL2 protein] Methylnitrosourea results in increased expression of BCL2 mRNA
|
CTD |
PMID:15240709 PMID:16011256 PMID:16047940 PMID:20732338 PMID:22465879 PMID:24463056 More...
|
|
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
|
|
| G
|
Bdnf
|
brain-derived neurotrophic factor
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of BDNF mRNA
|
CTD |
PMID:28688903 |
|
NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657
|
|
| G
|
Birc5
|
baculoviral IAP repeat-containing 5
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of BIRC5 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
|
Bmp5
|
bone morphogenetic protein 5
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of BMP5 gene
|
CTD |
PMID:10517996 PMID:17174358 |
|
NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189
|
|
| G
|
Bpnt1
|
3'(2'), 5'-bisphosphate nucleotidase 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of BPNT1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr13:99,397,127...99,425,056
Ensembl chr13:99,400,115...99,425,053
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of BTG2 mRNA
|
CTD |
PMID:21382384 |
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
Bub1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of BUB1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
|
|
| G
|
Capn1
|
calpain 1
|
decreases activity
|
EXP
|
Methylnitrosourea results in decreased activity of CAPN1 protein
|
CTD |
PMID:17069801 |
|
NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445
|
|
| G
|
Capn2
|
calpain 2
|
increases activity
|
EXP
|
Methylnitrosourea results in increased activity of CAPN2 protein
|
CTD |
PMID:17069801 |
|
NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625
|
|
| G
|
Car2
|
carbonic anhydrase 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CAR2 mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
|
|
| G
|
Casp3
|
caspase 3
|
multiple interactions
|
ISO EXP
|
MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]; MLH1 affects the reaction [MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]] [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP3 protein; [Methylnitrosourea co-treated with Estradiol] results in decreased expression of CASP3 mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP3 mRNA; [Methylnitrosourea co-treated with Progesterone] results in decreased expression of CASP3 mRNA
|
CTD |
PMID:13679151 PMID:20732338 PMID:22465879 |
|
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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|
| G
|
Casp6
|
caspase 6
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CASP6 mRNA
|
CTD |
PMID:28688903 |
|
NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726
|
|
| G
|
Casp8
|
caspase 8
|
multiple interactions increases expression
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in decreased activity of CASP8 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP8 mRNA Methylnitrosourea results in increased expression of CASP8 mRNA
|
CTD |
PMID:20732338 PMID:22465879 PMID:28688903 |
|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
|
|
| G
|
Casp9
|
caspase 9
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in decreased expression of CASP9 mRNA
|
CTD |
PMID:20732338 |
|
Ensembl chr 5:159,391,188...159,409,648
|
|
| G
|
Cat
|
catalase
|
decreases activity multiple interactions
|
EXP
|
Methylnitrosourea results in decreased activity of CAT protein [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased activity of CAT protein
|
CTD |
PMID:39197506 |
|
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
|
|
| G
|
Cbr1
|
carbonyl reductase 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CBR1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
|
|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
increases expression multiple interactions
|
EXP ISO
|
Methylnitrosourea results in increased expression of CCL2 mRNA Methylnitrosourea results in increased expression of CCL2 protein Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of CCL2 protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of CCL2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of CCL2 protein]
|
CTD |
PMID:16822543 PMID:17412507 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
|
|
| G
|
Ccl20
|
C-C motif chemokine ligand 20
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CCL20 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CCL3 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl4
|
C-C motif chemokine ligand 4
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CCL4 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CCL5 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccn2
|
cellular communication network factor 2
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of CCN2 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
|
|
| G
|
Ccn3
|
cellular communication network factor 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of CCN3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
|
|
| G
|
Ccna2
|
cyclin A2
|
increases expression decreases expression
|
ISO
|
Methylnitrosourea results in increased expression of CCNA2 mRNA; Methylnitrosourea results in increased expression of CCNA2 protein Methylnitrosourea results in decreased expression of CCNA2
|
CTD |
PMID:15870882 PMID:18593901 PMID:25270620 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
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|
| G
|
Ccnb1
|
cyclin B1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CCNB1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
|
|
| G
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Ccnd1
|
cyclin D1
|
increases expression multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of CCND1 protein [Methylnitrosourea co-treated with Estradiol] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Estradiol] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Testosterone] results in increased expression of CCND1 protein; Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of CCND1 protein]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of CCND1 protein]
|
CTD |
PMID:18155124 PMID:20732338 PMID:25164625 PMID:38977090 |
|
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccnd3
|
cyclin D3
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CCND3 protein
|
CTD |
PMID:18155124 |
|
NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
|
|
| G
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Cd59b
|
CD59b molecule
|
multiple interactions decreases lipidation
|
EXP
|
[Methylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [Methylnitrosourea results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein Methylnitrosourea results in decreased lipidation of CD59 protein
|
CTD |
PMID:19965957 PMID:20202993 PMID:27931811 |
|
NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310
|
|
| G
|
Cdh1
|
cadherin 1
|
multiple interactions decreases expression
|
EXP ISO
|
[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 mRNA; [Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 mRNA]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of CDH1 protein] Methylnitrosourea results in decreased expression of CDH1 mRNA
|
CTD |
PMID:25164625 PMID:27221058 |
|
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cdh2
|
cadherin 2
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of CDH2 mRNA; [Methylnitrosourea co-treated with Testosterone] results in increased expression of CDH2 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of CDH2 mRNA]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of CDH2 protein]
|
CTD |
PMID:25164625 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh22
|
cadherin 22
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of CDH22 mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
decreases expression increases expression
|
ISO EXP
|
Methylnitrosourea results in decreased expression of CDK1 Methylnitrosourea results in increased expression of CDK1 protein Methylnitrosourea results in increased expression of CDK1 mRNA
|
CTD |
PMID:15870882 PMID:16525678 PMID:18593901 |
|
NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
|
|
| G
|
Cdk2
|
cyclin dependent kinase 2
|
increases activity
|
EXP
|
Methylnitrosourea results in increased activity of CDK2 protein
|
CTD |
PMID:15581186 |
|
NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
|
|
| G
|
Cdk5r1
|
cyclin-dependent kinase 5 regulatory subunit 1
|
increases cleavage
|
EXP
|
Methylnitrosourea results in increased cleavage of CDK5R1 protein
|
CTD |
PMID:17069801 |
|
NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,978,911...65,989,272
|
|
| G
|
Cdk5rap1
|
CDK5 regulatory subunit associated protein 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of CDK5RAP1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 3:163,189,435...163,333,003
Ensembl chr 3:163,191,056...163,332,908
|
|
| G
|
Cdkn1a
|
cyclin-dependent kinase inhibitor 1A
|
increases expression decreases expression
|
ISO EXP
|
Methylnitrosourea results in increased expression of CDKN1A mRNA Methylnitrosourea results in decreased expression of CDKN1A protein
|
CTD |
PMID:15581186 PMID:18593901 PMID:28688903 PMID:29110037 |
|
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
|
|
| G
|
Cel
|
carboxyl ester lipase
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CEL mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019
|
|
| G
|
Cela2a
|
chymotrypsin like elastase 2A
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CELA2A mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 5:159,409,900...159,420,282
Ensembl chr 5:159,409,899...159,426,208
|
|
| G
|
Cenpa
|
centromere protein A
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of CENPA mRNA
|
CTD |
PMID:27233451 |
|
NCBI chr 6:31,420,062...31,431,703
|
|
| G
|
Cenpe
|
centromere protein E
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CENPE mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:226,310,970...226,369,636
Ensembl chr 2:226,300,798...226,369,636
|
|
| G
|
Cep290
|
centrosomal protein 290
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of CEP290 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 7:37,196,765...37,285,955
Ensembl chr 7:37,196,783...37,285,955
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
increases phosphorylation multiple interactions
|
ISO
|
Methylnitrosourea results in increased phosphorylation of CHEK2 protein MSH2 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of CHEK2 protein]
|
CTD |
PMID:21285353 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Ckap5
|
cytoskeleton associated protein 5
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CKAP5 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:97,946,966...98,049,050
Ensembl chr 3:97,947,031...98,049,049
|
|
| G
|
Cldn7
|
claudin 7
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of CLDN7 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
|
|
| G
|
Clu
|
clusterin
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CLU mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Col4a3
|
collagen type IV alpha 3 chain
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of COL4A3 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 9:91,323,990...91,453,088
Ensembl chr 9:91,323,990...91,453,077
|
|
| G
|
Col5a3
|
collagen type V alpha 3 chain
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of COL5A3 mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr 8:27,580,768...27,626,002
Ensembl chr 8:27,580,768...27,626,122
|
|
| G
|
Cpt1c
|
carnitine palmitoyltransferase 1c
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CPT1C mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 1:104,579,297...104,593,824
Ensembl chr 1:104,579,298...104,593,763
|
|
| G
|
Cradd
|
CASP2 and RIPK1 domain containing adaptor with death domain
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of CRADD gene
|
CTD |
PMID:16868089 |
|
NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:31,685,622...31,874,512
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein
|
CTD |
PMID:34186418 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CREM mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Crip2
|
cysteine-rich protein 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CRIP2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions increases expression
|
ISO
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of CSF2 protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of CSF2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of CSF2 protein]
|
CTD |
PMID:16822543 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Ctcf
|
CCCTC-binding factor
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of CTCF mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of CTNNB1 protein
|
CTD |
PMID:12096346 |
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
|
|
| G
|
Cwc27
|
CWC27 spliceosome associated cyclophilin
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of CWC27 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:37,498,462...37,709,691
Ensembl chr 2:37,498,468...37,709,355
|
|
| G
|
Cxcr1
|
C-X-C motif chemokine receptor 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of CXCR1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872
|
|
| G
|
Cyp27b1
|
cytochrome P450, family 27, subfamily b, polypeptide 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of CYP27B1 mRNA
|
CTD |
PMID:21843606 |
|
NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570
|
|
| G
|
Cyp2j4
|
cytochrome P450, family 2, subfamily j, polypeptide 4
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of CYP2J9 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042
|
|
| G
|
Dapk1
|
death associated protein kinase 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of DAPK1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
|
|
| G
|
Dbi
|
diazepam binding inhibitor
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of DBI mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
|
|
| G
|
Dbp
|
D-box binding PAR bZIP transcription factor
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of DBP mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
|
|
| G
|
Dcaf4
|
DDB1 and CUL4 associated factor 4
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of DCAF4 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 6:108,885,970...108,912,116
Ensembl chr 6:108,885,932...108,912,110
|
|
| G
|
Ddit4l
|
DNA-damage-inducible transcript 4-like
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of DDIT4L mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
|
|
| G
|
Depdc7
|
DEP domain containing 7
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of DEPDC7 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:111,554,706...111,575,979
|
|
| G
|
Dio1
|
iodothyronine deiodinase 1
|
multiple interactions
|
EXP
|
Methylnitrosourea inhibits the reaction [Iodine results in increased expression of DIO1 mRNA]
|
CTD |
PMID:15922087 |
|
NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771
|
|
| G
|
Dlgap1
|
DLG associated protein 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of DLGAP1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 9:117,304,144...118,173,463
Ensembl chr 9:117,614,061...118,173,463
|
|
| G
|
Dmbt1
|
deleted in malignant brain tumors 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of DMBT1 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:195,047,713...195,126,704
|
|
| G
|
Dnajb5
|
DnaJ heat shock protein family (Hsp40) member B5
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of DNAJB5 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:61,972,706...61,981,860
|
|
| G
|
Dnajc7
|
DnaJ heat shock protein family (Hsp40) member C7
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of DNAJC7 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489
|
|
| G
|
Dnpep
|
aspartyl aminopeptidase
|
decreases activity
|
EXP
|
Methylnitrosourea results in decreased activity of DNPEP protein
|
CTD |
PMID:16537183 |
|
NCBI chr 9:84,248,581...84,257,484
Ensembl chr 9:84,233,486...84,256,977
|
|
| G
|
Dpysl3
|
dihydropyrimidinase-like 3
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of DPYSL3 mRNA
|
CTD |
PMID:28688903 |
|
NCBI chr18:35,625,357...35,731,152
Ensembl chr18:35,625,357...35,731,152
|
|
| G
|
Dusp5
|
dual specificity phosphatase 5
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of DUSP5 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
|
|
| G
|
Dym
|
dymeclin
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of DYM gene
|
CTD |
PMID:16868089 |
|
NCBI chr18:70,879,835...71,176,006
Ensembl chr18:70,880,255...71,176,004
|
|
| G
|
Ech1
|
enoyl-CoA hydratase 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of ECH1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440
|
|
| G
|
Edf1
|
endothelial differentiation-related factor 1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of EDF1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:28,764,906...28,779,499
|
|
| G
|
Ednrb
|
endothelin receptor type B
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of EDNRB gene
|
CTD |
PMID:17174358 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
|
|
| G
|
Eed
|
embryonic ectoderm development
|
affects response to substance
|
ISO
|
EED protein affects the susceptibility to Methylnitrosourea
|
CTD |
PMID:11803473 |
|
NCBI chr 1:153,280,419...153,307,537
Ensembl chr 1:153,280,422...153,307,500
|
|
| G
|
Efna3
|
ephrin A3
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of EFNA3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843
|
|
| G
|
Efs
|
embryonal Fyn-associated substrate
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of EFS mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr15:32,362,401...32,374,490
Ensembl chr15:32,361,843...32,371,743
|
|
| G
|
Egf
|
epidermal growth factor
|
multiple interactions increases expression
|
EXP
|
[6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of EGF mRNA Methylnitrosourea results in increased expression of EGF mRNA
|
CTD |
PMID:39197506 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein; Hexachlorobenzene promotes the reaction [Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]]; Hexachlorobenzene promotes the reaction [Methylnitrosourea results in increased phosphorylation of EGFR protein]; Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]; Methylnitrosourea promotes the reaction [Hexachlorobenzene promotes the reaction [EGFR protein binds to SRC protein]]; Methylnitrosourea promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]; Methylnitrosourea results in increased phosphorylation of and results in decreased expression of EGFR protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein]
|
CTD |
PMID:22245120 PMID:25164625 |
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Egln3
|
egl-9 family hypoxia-inducible factor 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of EGLN3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015
|
|
| G
|
Eif2s2
|
eukaryotic translation initiation factor 2 subunit beta
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of EIF2S2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570
|
|
| G
|
Eif4ebp1
|
eukaryotic translation initiation factor 4E binding protein 1
|
multiple interactions increases phosphorylation
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of EIF4EBP1 protein; Methylnitrosourea promotes the reaction [sodium arsenite results in increased phosphorylation of EIF4EBP1 protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased phosphorylation of EIF4EBP1 protein]
|
CTD |
PMID:22465879 PMID:38977090 |
|
NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
|
|
| G
|
Elovl6
|
ELOVL fatty acid elongase 6
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ELOVL6 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549
|
|
| G
|
Eomes
|
eomesodermin
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of EOMES mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 8:127,059,215...127,067,070
Ensembl chr 8:127,059,215...127,067,070
|
|
| G
|
Ephx1
|
epoxide hydrolase 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of EPHX1 mRNA
|
CTD |
PMID:21382384 |
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
|
|
| G
|
Ercc4
|
ERCC excision repair 4, endonuclease catalytic subunit
|
decreases expression increases expression
|
ISO
|
Methylnitrosourea results in decreased expression of ERCC4 mRNA Methylnitrosourea results in increased expression of ERCC4 mRNA
|
CTD |
PMID:16616109 |
|
NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
|
|
| G
|
Ergic3
|
ERGIC and golgi 3
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of ERGIC3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:164,985,108...164,994,897
Ensembl chr 3:164,984,853...164,994,897
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions increases expression decreases phosphorylation increases response to substance
|
EXP
|
[6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of ESR1 mRNA; [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA]; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of ESR1 protein; Hexachlorobenzene promotes the reaction [Methylnitrosourea results in decreased phosphorylation of ESR1 protein]; Methylnitrosourea inhibits the reaction [Hexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein]] Methylnitrosourea results in increased expression of ESR1 mRNA ESR1 protein results in increased susceptibility to Methylnitrosourea
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CTD |
PMID:15528971 PMID:16891317 PMID:22245120 PMID:34186418 PMID:39197506 |
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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| G
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Ezr
|
ezrin
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increases expression
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EXP
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Methylnitrosourea results in increased expression of EZR mRNA
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CTD |
PMID:17412507 |
|
NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573
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| G
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F3
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coagulation factor III, tissue factor
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increases expression
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EXP
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Methylnitrosourea results in increased expression of F3 mRNA
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CTD |
PMID:17412507 |
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NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369
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| G
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Fabp3
|
fatty acid binding protein 3
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increases expression
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EXP
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Methylnitrosourea results in increased expression of FABP3 mRNA
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CTD |
PMID:17341692 |
|
NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881
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| G
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Faim2
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Fas apoptotic inhibitory molecule 2
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increases expression
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EXP
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Methylnitrosourea results in increased expression of FAIM2 mRNA
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CTD |
PMID:17412507 |
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NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026
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| G
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Fam187b
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family with sequence similarity 187, member B
|
decreases expression
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ISO
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Methylnitrosourea results in decreased expression of FAM187B mRNA
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CTD |
PMID:25270620 |
|
NCBI chr 1:95,329,482...95,346,940
Ensembl chr 1:95,332,631...95,371,536
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| G
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Fasn
|
fatty acid synthase
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increases expression
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EXP
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Methylnitrosourea results in increased expression of FASN mRNA
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CTD |
PMID:16525678 |
|
NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
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| G
|
Fbp2
|
fructose-bisphosphatase 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of FBP2 mRNA
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CTD |
PMID:25270620 |
|
NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366
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| G
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Fbxo15
|
F-box protein 15
|
decreases expression
|
ISO
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Methylnitrosourea results in decreased expression of FBXO15 mRNA
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CTD |
PMID:25270620 |
|
NCBI chr18:80,594,444...80,909,549
Ensembl chr 6:51,576,566...51,577,639 Ensembl chr18:51,576,566...51,577,639
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|
| G
|
Fbxo5
|
F-box protein 5
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increases expression
|
ISO
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Methylnitrosourea results in increased expression of FBXO5 mRNA
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CTD |
PMID:25270620 |
|
NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781
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|
| G
|
Fgf1
|
fibroblast growth factor 1
|
multiple interactions
|
EXP
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FGF1 protein modified form inhibits the reaction [Methylnitrosourea results in decreased expression of BCL2 protein]; FGF1 protein modified form inhibits the reaction [Methylnitrosourea results in increased expression of BAX protein]
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CTD |
PMID:16011256 |
|
NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393
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| G
|
Fgfr1
|
Fibroblast growth factor receptor 1
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multiple interactions
|
EXP
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Methylnitrosourea results in increased expression of and affects the localization of FGFR1 protein
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CTD |
PMID:15581186 |
|
NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855
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| G
|
Fgfr2
|
fibroblast growth factor receptor 2
|
multiple interactions
|
EXP
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Methylnitrosourea results in increased expression of and affects the localization of FGFR2 protein
|
CTD |
PMID:15581186 |
|
NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914
|
|
| G
|
Fgfr4
|
fibroblast growth factor receptor 4
|
multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of and affects the localization of FGFR4 protein
|
CTD |
PMID:15581186 |
|
NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389
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|
| G
|
Fhit
|
fragile histidine triad diadenosine triphosphatase
|
increases methylation decreases expression
|
EXP
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Methylnitrosourea results in increased methylation of FHIT intron; Methylnitrosourea results in increased methylation of FHIT promoter Methylnitrosourea results in decreased expression of FHIT mRNA; Methylnitrosourea results in decreased expression of FHIT protein
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CTD |
PMID:15937960 PMID:17412507 |
|
NCBI chr15:16,365,401...17,872,901
Ensembl chr15:16,747,338...17,872,621
|
|
| G
|
Fos
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
increases expression multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of FOS mRNA; Methylnitrosourea results in increased expression of FOS protein [tetramethylpyrazine affects the expression of FOS mRNA] which results in decreased susceptibility to Methylnitrosourea; Niacinamide inhibits the reaction [Methylnitrosourea results in increased expression of FOS protein]
|
CTD |
PMID:16168987 PMID:16268501 PMID:17412507 |
|
NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
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|
| G
|
Foxa1
|
forkhead box A1
|
decreases expression
|
ISO
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Methylnitrosourea results in decreased expression of FOXA1 mRNA
|
CTD |
PMID:27221058 |
|
NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191
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|
| G
|
Foxa2
|
forkhead box A2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of FOXA2 mRNA
|
CTD |
PMID:27221058 |
|
NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757
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|
| G
|
Fshb
|
follicle stimulating hormone subunit beta
|
multiple interactions decreases expression
|
EXP
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Hexachlorobenzene inhibits the reaction [Methylnitrosourea results in decreased expression of FSHB protein]
|
CTD |
PMID:22245120 |
|
NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072
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|
| G
|
Galnt16
|
polypeptide N-acetylgalactosaminyltransferase 16
|
increases mutagenesis
|
ISO
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Methylnitrosourea results in increased mutagenesis of GALNT16 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 6:105,900,987...105,982,039
Ensembl chr 6:105,901,153...105,991,350
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|
| G
|
Galnt6
|
polypeptide N-acetylgalactosaminyltransferase 6
|
increases expression
|
ISO
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Methylnitrosourea results in increased expression of GALNT6 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 7:133,668,612...133,715,909
Ensembl chr 7:133,668,615...133,698,439
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|
| G
|
Gbp2
|
guanylate binding protein 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of GBP2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810
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|
| G
|
Gfap
|
glial fibrillary acidic protein
|
increases expression decreases expression
|
EXP
|
Methylnitrosourea results in increased expression of GFAP protein Methylnitrosourea results in decreased expression of GFAP mRNA
|
CTD |
PMID:18155124 PMID:28688903 |
|
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685
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|
| G
|
Gh1
|
growth hormone 1
|
decreases response to substance
|
EXP
|
GH1 gene mutant form results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:12082019 |
|
NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
|
|
| G
|
Gjb1
|
gap junction protein, beta 1
|
decreases response to substance
|
ISO
|
GJB1 protein results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:17463168 |
|
NCBI chr X:70,541,845...70,549,776
Ensembl chr X:70,541,862...70,549,843
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|
| G
|
Glipr1l2
|
GLIPR1 like 2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of GLIPR1L2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 7:49,401,847...49,432,249
Ensembl chr 7:49,401,860...49,432,267
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|
| G
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Gmcl1
|
germ cell-less 1, spermatogenesis associated
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of GMCL1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 4:120,697,976...120,737,267
Ensembl chr 4:120,697,976...120,737,257
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|
| G
|
Gpx2
|
glutathione peroxidase 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of GPX2 mRNA; Methylnitrosourea results in increased expression of GPX2 protein
|
CTD |
PMID:18056462 |
|
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
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|
| G
|
Grb14
|
growth factor receptor bound protein 14
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of GRB14 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:69,976,339...70,091,921
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|
| G
|
Grb2
|
growth factor receptor bound protein 2
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 mRNA; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of GRB2 protein
|
CTD |
PMID:22465879 |
|
NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138
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|
| G
|
Grin2a
|
glutamate ionotropic receptor NMDA type subunit 2A
|
decreases expression increases expression
|
EXP
|
Methylnitrosourea results in decreased expression of GRIN2A mRNA Methylnitrosourea results in increased expression of GRIN2A mRNA
|
CTD |
PMID:28688903 |
|
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378
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|
| G
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Gsk3b
|
glycogen synthase kinase 3 beta
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in decreased expression of GSK3B protein]
|
CTD |
PMID:25164625 |
|
NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
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|
| G
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H2ax
|
H2A.X variant histone
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of H2AX protein modified form
|
CTD |
PMID:27233451 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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|
| G
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H2bc4
|
H2B clustered histone 4
|
decreases expression
|
ISO
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Methylnitrosourea results in decreased expression of H2BC4 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr17:47,388,085...47,392,349
Ensembl chr17:47,404,375...47,419,020
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|
| G
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Hba-a2
|
hemoglobin alpha, adult chain 2
|
increases carbamoylation
|
ISO
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Methylnitrosourea results in increased carbamoylation of HBA1 protein
|
CTD |
PMID:15655799 |
|
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
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|
| G
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Hba-a3
|
hemoglobin alpha, adult chain 3
|
increases carbamoylation
|
ISO
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Methylnitrosourea results in increased carbamoylation of HBA2 protein
|
CTD |
PMID:15655799 |
|
NCBI chr10:15,816,099...15,816,943
Ensembl chr10:15,816,096...15,817,167
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|
| G
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Hbb
|
hemoglobin subunit beta
|
increases carbamoylation
|
ISO
|
Methylnitrosourea results in increased carbamoylation of HBB protein
|
CTD |
PMID:15655799 |
|
NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873
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|
| G
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Hdac6
|
histone deacetylase 6
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of HDAC6 protein
|
CTD |
PMID:34186418 |
|
NCBI chr X:17,222,538...17,244,373
Ensembl chr X:17,222,856...17,244,370
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|
| G
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Hesx1
|
HESX homeobox 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of HESX1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr16:2,198,589...2,200,694
Ensembl chr16:2,198,589...2,200,694
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|
| G
|
Hgf
|
hepatocyte growth factor
|
decreases expression multiple interactions
|
ISO
|
Methylnitrosourea results in decreased expression of HGF mRNA Quercetin inhibits the reaction [Methylnitrosourea results in decreased expression of HGF mRNA]
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CTD |
PMID:18675455 |
|
NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
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| G
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Hif1a
|
hypoxia inducible factor 1 subunit alpha
|
multiple interactions increases expression
|
EXP
|
Methylnitrosourea promotes the reaction [sodium arsenite results in increased phosphorylation of HIF1A protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased phosphorylation of HIF1A protein] Methylnitrosourea results in increased expression of HIF1A protein
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CTD |
PMID:38977090 |
|
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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| G
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Hivep2
|
HIVEP zinc finger 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of HIVEP2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 1:10,176,880...10,376,089
Ensembl chr 1:10,179,402...10,376,089
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|
| G
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Hk2
|
hexokinase 2
|
increases expression multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of HK2 protein Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of HK2 protein]
|
CTD |
PMID:38977090 |
|
NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
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|
| G
|
Hmgb2
|
high mobility group box 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of HMGB2 mRNA; Methylnitrosourea results in increased expression of HMGB2 protein
|
CTD |
PMID:16525678 PMID:29877212 |
|
NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860
|
|
| G
|
Hmgb3
|
high mobility group box 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of HMGB3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr X:154,341,106...154,346,087
Ensembl chr X:154,340,935...154,346,097
|
|
| G
|
Hmox1
|
heme oxygenase 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of HMOX1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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|
| G
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Hprt1
|
hypoxanthine phosphoribosyltransferase 1
|
increases mutagenesis increases expression
|
EXP ISO
|
Methylnitrosourea results in increased mutagenesis of HPRT1 gene Methylnitrosourea results in increased expression of HPRT1 mRNA
|
CTD |
PMID:18249417 PMID:25270620 |
|
NCBI chr X:137,655,744...137,687,718
Ensembl chr X:137,655,680...137,687,712
|
|
| G
|
Hras
|
HRas proto-oncogene, GTPase
|
multiple interactions increases response to substance increases mutagenesis decreases response to substance
|
ISO EXP
|
limonene inhibits the reaction [HRAS protein results in increased susceptibility to Methylnitrosourea] Methylnitrosourea results in increased mutagenesis of HRAS gene HRAS protein results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:10767621 PMID:11182032 PMID:11376698 PMID:11802805 PMID:11973638 PMID:12117780 PMID:15688392 PMID:28421967 More...
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|
NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
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|
| G
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Id3
|
inhibitor of DNA binding 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of ID3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856
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|
| G
|
Ier3
|
immediate early response 3
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of IER3 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377
|
|
| G
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Ifng
|
interferon gamma
|
multiple interactions decreases response to substance
|
ISO EXP
|
IFNG protein inhibits the reaction [Methylnitrosourea results in decreased expression of IL10 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of CCL2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of CSF2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of IL2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of IL4 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of LEP protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of THPO protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of TNF protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of VEGFA protein] IFNG protein results in decreased susceptibility to Methylnitrosourea 2-Acetylaminofluorene inhibits the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein]; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IFNG protein
|
CTD |
PMID:14736494 PMID:15240709 PMID:16080182 PMID:16822543 |
|
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
|
|
| G
|
Ifrd1
|
interferon-related developmental regulator 1
|
multiple interactions increases expression
|
ISO
|
Quercetin inhibits the reaction [Methylnitrosourea results in increased expression of IFRD1 mRNA]
|
CTD |
PMID:18675455 |
|
NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131
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|
| G
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Igdcc4
|
immunoglobulin superfamily, DCC subclass, member 4
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of IGDCC4 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 8:74,517,082...74,552,834
Ensembl chr 8:74,517,086...74,552,834
|
|
| G
|
Igf1
|
insulin-like growth factor 1
|
increases response to substance
|
ISO
|
IGF1 protein results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:15528971 |
|
NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
|
|
| G
|
Igf1r
|
insulin-like growth factor 1 receptor
|
multiple interactions increases expression
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R mRNA; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of IGF1R protein; Hexachlorobenzene inhibits the reaction [Methylnitrosourea results in increased expression of IGF1R protein]
|
CTD |
PMID:16237195 PMID:22465879 |
|
NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
|
|
| G
|
Igfbp2
|
insulin-like growth factor binding protein 2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of IGFBP2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
|
|
| G
|
Ikzf1
|
IKAROS family zinc finger 1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of IKZF1 mRNA
|
CTD |
PMID:16616109 |
|
NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574
|
|
| G
|
Il10
|
interleukin 10
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in decreased expression of IL10 protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in decreased expression of IL10 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in decreased expression of IL10 protein] Methylnitrosourea results in increased expression of IL10 mRNA; Methylnitrosourea results in increased expression of IL10 protein
|
CTD |
PMID:14999141 PMID:16822543 |
|
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
|
|
| G
|
Il17b
|
interleukin 17B
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of IL17B mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr18:57,411,532...57,415,903
Ensembl chr18:57,411,532...57,415,903
|
|
| G
|
Il1b
|
interleukin 1 beta
|
increases expression multiple interactions
|
ISO EXP
|
Methylnitrosourea results in increased expression of IL1B mRNA Quercetin inhibits the reaction [Methylnitrosourea results in increased expression of IL1B mRNA]
|
CTD |
PMID:17412507 PMID:18675455 |
|
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
|
|
| G
|
Il2
|
interleukin 2
|
multiple interactions increases expression
|
ISO EXP
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of IL2 protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of IL2 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of IL2 protein] [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with Butylhydroxybutylnitrosamine co-treated with diisopropanolnitrosamine co-treated with 1,2-Dimethylhydrazine] results in decreased expression of IL2 protein
|
CTD |
PMID:14736494 PMID:16822543 |
|
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
|
|
| G
|
Il4
|
interleukin 4
|
multiple interactions increases expression
|
ISO
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of IL4 protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of IL4 protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of IL4 protein]
|
CTD |
PMID:16822543 |
|
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
|
|
| G
|
Insr
|
insulin receptor
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of INSR protein
|
CTD |
PMID:16237195 |
|
NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
|
|
| G
|
Irf1
|
interferon regulatory factor 1
|
decreases response to substance increases expression
|
ISO EXP
|
IRF1 protein results in decreased susceptibility to Methylnitrosourea Methylnitrosourea results in increased expression of IRF1 mRNA
|
CTD |
PMID:15240709 PMID:17412507 |
|
NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947
|
|
| G
|
Irs1
|
insulin receptor substrate 1
|
multiple interactions increases phosphorylation
|
EXP
|
Hexachlorobenzene inhibits the reaction [Methylnitrosourea results in increased phosphorylation of IRS1 protein]
|
CTD |
PMID:16237195 |
|
NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
|
|
| G
|
Jam2
|
junctional adhesion molecule 2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of JAM2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510
|
|
| G
|
Jun
|
Jun proto-oncogene, AP-1 transcription factor subunit
|
increases expression multiple interactions increases phosphorylation
|
EXP
|
Methylnitrosourea results in increased expression of JUN protein [tetramethylpyrazine affects the expression of JUN mRNA] which results in decreased susceptibility to Methylnitrosourea; Niacinamide inhibits the reaction [Methylnitrosourea results in increased expression of JUN protein]; Niacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of JUN protein]
|
CTD |
PMID:16168987 PMID:16268501 |
|
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
|
|
| G
|
Junb
|
JunB proto-oncogene, AP-1 transcription factor subunit
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of JUNB mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218
|
|
| G
|
Kif3b
|
kinesin family member 3B
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of KIF3B gene
|
CTD |
PMID:16868089 |
|
NCBI chr 3:162,218,621...162,258,191
Ensembl chr 3:162,218,682...162,258,581
|
|
| G
|
Kitlg
|
KIT ligand
|
decreases expression multiple interactions
|
ISO
|
Methylnitrosourea results in decreased expression of KITL mRNA Quercetin inhibits the reaction [Methylnitrosourea results in decreased expression of KITL mRNA]
|
CTD |
PMID:18675455 |
|
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
|
|
| G
|
Klhl22
|
kelch-like family member 22
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of KLHL22 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr11:96,695,168...96,736,079
Ensembl chr11:96,695,171...96,738,065
|
|
| G
|
Klk1
|
kallikrein 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of KLK1 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270
|
|
| G
|
Kras
|
KRAS proto-oncogene, GTPase
|
decreases response to substance increases mutagenesis
|
EXP ISO
|
KRAS protein results in decreased susceptibility to Methylnitrosourea Methylnitrosourea results in increased mutagenesis of KRAS gene
|
CTD |
PMID:11973638 PMID:12483526 PMID:18062963 |
|
NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320
|
|
| G
|
Lcn2
|
lipocalin 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of LCN2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842
|
|
| G
|
Lep
|
leptin
|
multiple interactions increases expression
|
ISO
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of LEP protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of LEP protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of LEP protein]
|
CTD |
PMID:16822543 |
|
NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
|
|
| G
|
Lgals3
|
galectin 3
|
decreases expression increases expression
|
ISO EXP
|
Methylnitrosourea results in decreased expression of LGALS3 mRNA N-methyl-N-nitrosourea increases expression of Lgals3 protein in serum
|
CTD RGD |
PMID:25270620 PMID:28032729 |
RGD:150530464 |
NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737
|
|
| G
|
Ltb
|
lymphotoxin beta
|
decreases response to substance
|
ISO
|
LTB protein results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:15240709 |
|
NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054
|
|
| G
|
Macrod2
|
mono-ADP ribosylhydrolase 2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of MACROD2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:148,173,821...150,191,077
Ensembl chr 3:148,173,829...150,188,058
|
|
| G
|
Mad2l2
|
mitotic arrest deficient 2 like 2
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of MAD2L2 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:163,846,687...163,859,851
|
|
| G
|
Madcam1
|
mucosal vascular addressin cell adhesion molecule 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of MADCAM1 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 7:10,686,920...10,690,322
Ensembl chr 7:10,686,250...10,690,322
|
|
| G
|
Map2k1
|
mitogen activated protein kinase kinase 1
|
multiple interactions
|
EXP
|
Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAP2K1 protein
|
CTD |
PMID:12693035 |
|
NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
|
|
| G
|
Mapk1
|
mitogen activated protein kinase 1
|
increases response to substance multiple interactions
|
EXP
|
MAPK1 protein modified form results in increased susceptibility to Methylnitrosourea; MAPK1 protein results in increased susceptibility to Methylnitrosourea 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Methylnitrosourea results in increased activity of MAPK1 protein]; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MAPK1 protein; [Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of MAPK1 protein; Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of MAPK1 protein]
|
CTD |
PMID:12693035 PMID:15528971 PMID:22465879 PMID:25164625 |
|
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
|
|
| G
|
Mapk14
|
mitogen activated protein kinase 14
|
multiple interactions
|
EXP
|
Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK14 protein
|
CTD |
PMID:12693035 |
|
NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
|
|
| G
|
Mapk3
|
mitogen activated protein kinase 3
|
increases response to substance multiple interactions
|
EXP
|
MAPK3 protein modified form results in increased susceptibility to Methylnitrosourea; MAPK3 protein results in increased susceptibility to Methylnitrosourea 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Methylnitrosourea results in increased activity of MAPK3 protein]; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MAPK3 protein; [Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of MAPK3 protein; Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK3 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of MAPK3 protein]
|
CTD |
PMID:12693035 PMID:15528971 PMID:22465879 PMID:25164625 |
|
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
|
|
| G
|
Mapk8
|
mitogen-activated protein kinase 8
|
multiple interactions increases phosphorylation increases activity decreases response to substance
|
ISO EXP
|
Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein] Methylnitrosourea results in increased phosphorylation of MAPK8 protein Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased activity of MAPK8 protein]; Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK8 protein; Niacinamide inhibits the reaction [Methylnitrosourea results in increased phosphorylation of MAPK8 protein] MAPK8 gene mutant form results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:12693035 PMID:16168987 PMID:18593901 |
|
NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
|
|
| G
|
Mapkapk3
|
MAPK activated protein kinase 3
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of MAPKAPK3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228
|
|
| G
|
Mbp
|
myelin basic protein
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of MBP mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174
|
|
| G
|
Mcam
|
melanoma cell adhesion molecule
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of MCAM mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 8:53,376,225...53,384,407
Ensembl chr 8:53,376,197...53,384,406
|
|
| G
|
Mdm2
|
MDM2 proto-oncogene
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MDM2 mRNA
|
CTD |
PMID:28688903 |
|
NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
|
|
| G
|
Me1
|
malic enzyme 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ME1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
|
|
| G
|
Mgmt
|
O-6-methylguanine-DNA methyltransferase
|
increases alkylation increases expression decreases response to substance multiple interactions
|
ISO EXP
|
Methylnitrosourea results in increased alkylation of MGMT protein Methylnitrosourea results in increased expression of MGMT mRNA MGMT protein results in decreased susceptibility to Methylnitrosourea MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]; MGMT protein inhibits the reaction [TRP53 gene mutant form results in increased susceptibility to Methylnitrosourea]; MLH1 affects the reaction [MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]]; MLH1 protein promotes the reaction [MGMT protein results in decreased susceptibility to Methylnitrosourea] MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]
|
CTD |
PMID:8823159 PMID:11276365 PMID:11536039 PMID:12663516 PMID:13679151 PMID:15870882 PMID:17507295 PMID:23288051 PMID:28688903 More...
|
|
NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482
|
|
| G
|
Mipol1
|
mirror-image polydactyly 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of MIPOL1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 6:80,490,330...80,825,413
Ensembl chr 6:80,490,312...80,825,413
|
|
| G
|
Mir185
|
microRNA 185
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MIR185 mRNA
|
CTD |
PMID:30336191 |
|
NCBI chr11:96,169,028...96,169,107
Ensembl chr11:96,169,028...96,169,107
|
|
| G
|
Mir96
|
microRNA 96
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MIR96 mRNA
|
CTD |
PMID:30336191 |
|
NCBI chr 4:59,755,841...59,755,946
|
|
| G
|
Mki67
|
marker of proliferation Ki-67
|
increases expression multiple interactions
|
ISO EXP
|
Methylnitrosourea results in increased expression of MKI67 mRNA Methylnitrosourea results in increased expression of MKI67 protein Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of MKI67 protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased expression of MKI67 protein]
|
CTD |
PMID:25270620 PMID:38977090 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
|
|
| G
|
Mlf1
|
myeloid leukemia factor 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MLF1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 2:153,958,060...153,991,705
Ensembl chr 2:153,958,546...153,994,220
|
|
| G
|
Mlh1
|
mutL homolog 1
|
multiple interactions affects response to substance
|
ISO
|
Methylnitrosourea promotes the reaction [MSH2 protein binds to MLH1 protein binds to PMS2 protein] MLH1 protein affects the susceptibility to Methylnitrosourea MLH1 affects the reaction [MGMT protein affects the reaction [Methylnitrosourea results in increased activity of CASP3 protein]]; MLH1 protein promotes the reaction [MGMT protein results in decreased susceptibility to Methylnitrosourea]
|
CTD |
PMID:12967659 PMID:13679151 PMID:16204460 |
|
NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011
|
|
| G
|
Mlx
|
MAX dimerization protein MLX
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of MLX mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:86,519,517...86,524,607
Ensembl chr10:86,519,864...86,524,772
|
|
| G
|
Mmp3
|
matrix metallopeptidase 3
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MMP3 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
|
|
| G
|
Mpc1
|
mitochondrial pyruvate carrier 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of MPC1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064
|
|
| G
|
Mpg
|
N-methylpurine-DNA glycosylase
|
decreases response to substance increases response to substance
|
ISO
|
MPG protein results in decreased susceptibility to Methylnitrosourea MPG protein results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:15299078 PMID:16288039 PMID:17674369 |
|
NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052
|
|
| G
|
Mrpl47
|
mitochondrial ribosomal protein L47
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of MRPL47 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:117,436,199...117,447,790
Ensembl chr 2:117,428,621...117,447,517
|
|
| G
|
Mrps31
|
mitochondrial ribosomal protein S31
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of MRPS31 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr16:76,303,807...76,332,970
Ensembl chr16:76,301,645...76,333,065
|
|
| G
|
Msc
|
musculin
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of MSC mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:9,330,544...9,336,857
|
|
| G
|
Msh2
|
mutS homolog 2
|
multiple interactions increases response to substance affects response to substance
|
ISO
|
Methylnitrosourea promotes the reaction [MSH2 protein binds to MLH1 protein binds to PMS2 protein]; Methylnitrosourea promotes the reaction [MSH2 protein binds to PCNA protein binds to MSH6 protein] MSH2 protein results in increased susceptibility to Methylnitrosourea MSH2 protein affects the susceptibility to Methylnitrosourea MSH2 protein promotes the reaction [Methylnitrosourea affects the localization of ATR protein]; MSH2 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of CHEK2 protein]; MSH2 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]
|
CTD |
PMID:12185594 PMID:16204460 PMID:21285353 |
|
NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503
|
|
| G
|
Msh6
|
mutS homolog 6
|
multiple interactions
|
ISO
|
Methylnitrosourea promotes the reaction [MSH2 protein binds to PCNA protein binds to MSH6 protein]
|
CTD |
PMID:16204460 |
|
NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:12,316,198...12,333,844
|
|
| G
|
Mt1a
|
metallothionein 1A
|
multiple interactions increases expression
|
ISO
|
[Methylnitrosourea co-treated with Carrageenan] results in increased expression of MT1 protein Methylnitrosourea results in increased expression of MT1 protein
|
CTD |
PMID:15928667 |
|
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
|
|
| G
|
Mthfd2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of MTHFD2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
|
|
| G
|
Mtor
|
mechanistic target of rapamycin kinase
|
multiple interactions increases phosphorylation
|
EXP ISO
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MTOR protein; [Methylnitrosourea co-treated with Testosterone] results in increased expression of MTOR protein; Methylnitrosourea promotes the reaction [sodium arsenite results in increased phosphorylation of MTOR protein]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of MTOR protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased phosphorylation of MTOR protein] Methylnitrosourea promotes the reaction [sodium arsenite results in increased phosphorylation of MTOR protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased phosphorylation of MTOR protein]
|
CTD |
PMID:22465879 PMID:25164625 PMID:38977090 |
|
NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
|
|
| G
|
Myc
|
MYC proto-oncogene, bHLH transcription factor
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Methylnitrosourea results in increased expression of MYC mRNA [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [Diethylhexyl Phthalate co-treated with bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of MYC protein Methylnitrosourea results in decreased expression of MYC mRNA
|
CTD |
PMID:16616109 PMID:17412507 PMID:25270620 PMID:34186418 |
|
NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
|
|
| G
|
Myo5a
|
myosin VA
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of MYO5A gene
|
CTD |
PMID:10517996 PMID:17174358 |
|
NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265
|
|
| G
|
Ncor2
|
nuclear receptor co-repressor 2
|
affects expression
|
EXP
|
Methylnitrosourea affects the expression of NCOR2 mRNA
|
CTD |
PMID:21843606 |
|
NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612
|
|
| G
|
Nectin1
|
nectin cell adhesion molecule 1
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of NECTIN1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 8:52,998,662...53,061,745
Ensembl chr 8:52,998,662...53,086,664
|
|
| G
|
Nes
|
nestin
|
increases expression increases methylation
|
EXP ISO
|
Methylnitrosourea results in increased expression of NES protein Methylnitrosourea results in increased methylation of NES gene
|
CTD |
PMID:18155124 PMID:25922126 |
|
NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228
|
|
| G
|
Nfkbia
|
NFKB inhibitor alpha
|
multiple interactions increases expression
|
EXP
|
[Methylnitrosourea results in increased expression of NFKBIA protein] which affects the localization of RELA protein; tetramethylpyrazine inhibits the reaction [Methylnitrosourea results in increased expression of NFKBIA protein]
|
CTD |
PMID:15960898 PMID:16098260 PMID:16762860 |
|
NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
|
|
| G
|
Nme5
|
NME/NM23 family member 5
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of NME5 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,437,781...26,454,828
|
|
| G
|
Nnat
|
neuronatin
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of NNAT mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086
|
|
| G
|
Nnmt
|
nicotinamide N-methyltransferase
|
increases activity
|
EXP
|
Methylnitrosourea results in increased activity of NNMT protein
|
CTD |
PMID:6652621 |
|
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
|
|
| G
|
Nos2
|
nitric oxide synthase 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of NOS2 protein
|
CTD |
PMID:16052507 |
|
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
|
|
| G
|
Nrxn3
|
neurexin 3
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of NRXN3 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 6:113,372,667...115,004,073
Ensembl chr 6:113,443,524...115,002,540
|
|
| G
|
Ntm
|
neurotrimin
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of NTM mRNA
|
CTD |
PMID:25922126 |
|
NCBI chr 8:35,634,929...36,625,081
Ensembl chr 8:35,635,640...36,624,807
|
|
| G
|
Nusap1
|
nucleolar and spindle associated protein 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of NUSAP1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237
|
|
| G
|
Oaf
|
out at first homolog
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of OAF mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285
|
|
| G
|
Oca2
|
OCA2 melanosomal transmembrane protein
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of OCA2 gene
|
CTD |
PMID:10517996 PMID:17174358 |
|
NCBI chr 1:116,252,026...116,581,838
Ensembl chr 1:116,251,796...116,581,838
|
|
| G
|
Ogfrl1
|
opioid growth factor receptor-like 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of OGFRL1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 9:33,320,501...33,338,742
Ensembl chr 9:33,324,392...33,339,237
|
|
| G
|
Opn4
|
opsin 4
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of OPN4 mRNA; Methylnitrosourea results in decreased expression of OPN4 protein
|
CTD |
PMID:16580133 |
|
NCBI chr16:9,926,638...9,935,810
Ensembl chr16:9,926,902...9,949,928
|
|
| G
|
Pafah2
|
platelet-activating factor acetylhydrolase 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PAFAH2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:151,890,751...151,919,896
Ensembl chr 5:151,896,832...151,919,894
|
|
| G
|
Parg
|
poly (ADP-ribose) glycohydrolase
|
increases response to substance
|
ISO
|
PARG gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:15282315 |
|
NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
|
|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases response to substance multiple interactions increases activity affects response to substance
|
ISO EXP
|
PARP1 gene mutant form results in increased susceptibility to Methylnitrosourea Niacinamide inhibits the reaction [Methylnitrosourea results in increased activity of PARP1 protein] PARP1 protein affects the susceptibility to Methylnitrosourea PARP1 protein affects the reaction [Methylnitrosourea affects the activity of TRP53 protein]; PARP1 protein affects the reaction [Methylnitrosourea affects the expression of TRP53 protein]; PARP1 protein promotes the reaction [Methylnitrosourea affects the metabolism of SOD2 protein]
|
CTD |
PMID:11850828 PMID:15282315 PMID:16052507 PMID:16168987 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Parp2
|
poly (ADP-ribose) polymerase 2
|
increases response to substance
|
ISO
|
PARP2 gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:12727891 |
|
NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891
|
|
| G
|
Patj
|
PATJ, crumbs cell polarity complex component
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PATJ mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 5:118,177,557...118,480,301
Ensembl chr 5:118,177,565...118,480,301
|
|
| G
|
Pbk
|
PDZ binding kinase
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PBK mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570
|
|
| G
|
Pc
|
pyruvate carboxylase
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of PC mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940
|
|
| G
|
Pcna
|
proliferating cell nuclear antigen
|
multiple interactions increases expression
|
ISO EXP
|
Methylnitrosourea promotes the reaction [MSH2 protein binds to PCNA protein binds to MSH6 protein] [6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of PCNA protein; [Methylnitrosourea co-treated with Testosterone] results in increased expression of PCNA protein; Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of PCNA protein]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of PCNA protein]; sodium arsenite promotes the reaction [Methylnitrosourea results in increased expression of PCNA protein]
|
CTD |
PMID:16204460 PMID:18155124 PMID:25164625 PMID:38977090 PMID:39197506 |
|
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
|
|
| G
|
Pdk1
|
pyruvate dehydrogenase kinase 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of PDK1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
|
|
| G
|
Pdpk1
|
3-phosphoinositide dependent protein kinase-1
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein]
|
CTD |
PMID:25164625 |
|
NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181
|
|
| G
|
Perp
|
p53 apoptosis effector related to PMP22
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PERP mRNA
|
CTD |
PMID:21382384 PMID:25270620 |
|
NCBI chr 1:15,361,784...15,374,230
Ensembl chr 1:15,361,778...15,374,687
|
|
| G
|
Pfkp
|
phosphofructokinase, platelet
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of PFKP mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752
|
|
| G
|
Pgr
|
progesterone receptor
|
multiple interactions
|
EXP
|
[6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of PGR protein
|
CTD |
PMID:39197506 |
|
NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
|
|
| G
|
Phlda3
|
pleckstrin homology-like domain, family A, member 3
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PHLDA3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621
|
|
| G
|
Pias2
|
protein inhibitor of activated STAT, 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PIAS2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662
|
|
| G
|
Piezo1
|
piezo-type mechanosensitive ion channel component 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of PIEZO1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr19:67,453,120...67,515,347
Ensembl chr19:67,453,122...67,515,037
|
|
| G
|
Piga
|
phosphatidylinositol glycan anchor biosynthesis, class A
|
multiple interactions increases mutagenesis
|
EXP
|
[Methylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein] which affects the localization of CD59 protein; [Methylnitrosourea results in increased mutagenesis of PIGA gene] which results in decreased expression of CD59 protein; Methylnitrosourea results in increased mutagenesis of and results in decreased activity of PIGA protein Methylnitrosourea results in increased mutagenesis of PIGA; Methylnitrosourea results in increased mutagenesis of PIGA gene
|
CTD |
PMID:19965957 PMID:20202993 PMID:22923490 PMID:27931811 |
|
NCBI chr X:33,672,832...33,687,747
Ensembl chr X:33,674,923...33,687,636
|
|
| G
|
Pinx1
|
PIN2/TERF1 interacting, telomerase inhibitor 1
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of PINX1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr15:42,273,805...42,333,047
Ensembl chr15:42,273,799...42,333,047
|
|
| G
|
Pkib
|
cAMP-dependent protein kinase inhibitor beta
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of PKIB mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr20:37,511,564...37,608,607
Ensembl chr20:37,512,822...37,608,401
|
|
| G
|
Pkm
|
pyruvate kinase M1/2
|
increases expression multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of PKM protein Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of PKM protein]
|
CTD |
PMID:38977090 |
|
NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
|
|
| G
|
Pmaip1
|
phorbol-12-myristate-13-acetate-induced protein 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PMAIP1 mRNA
|
CTD |
PMID:18593901 |
|
NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382
|
|
| G
|
Pms2
|
PMS1 homolog 2, mismatch repair system component
|
multiple interactions increases response to substance affects response to substance
|
ISO
|
Methylnitrosourea promotes the reaction [MSH2 protein binds to MLH1 protein binds to PMS2 protein] PMS2 protein results in increased susceptibility to Methylnitrosourea PMS2 protein affects the susceptibility to Methylnitrosourea
|
CTD |
PMID:12967659 PMID:16204460 PMID:16426742 |
|
NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248
|
|
| G
|
Polb
|
DNA polymerase beta
|
increases response to substance
|
ISO
|
POLB gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:17166880 |
|
NCBI chr16:76,081,903...76,105,174
Ensembl chr16:76,081,864...76,108,180
|
|
| G
|
Pparg
|
peroxisome proliferator-activated receptor gamma
|
increases response to substance
|
ISO
|
PPARG gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:15930296 |
|
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
|
|
| G
|
Ppp1r10
|
protein phosphatase 1, regulatory subunit 10
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of PPP1R10 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418
|
|
| G
|
Praf2
|
PRA1 domain family, member 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PRAF2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr X:17,445,313...17,447,950
Ensembl chr X:17,445,313...17,447,950
|
|
| G
|
Prc1
|
protein regulator of cytokinesis 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PRC1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012
|
|
| G
|
Prdm14
|
PR/SET domain 14
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of PRDM14 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:10,864,137...10,876,666
Ensembl chr 5:10,864,137...10,876,666
|
|
| G
|
Prl
|
prolactin
|
multiple interactions
|
EXP
|
[6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt co-treated with Methylnitrosourea] results in increased expression of PRL protein
|
CTD |
PMID:39197506 |
|
NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
|
|
| G
|
Prune1
|
prune exopolyphosphatase 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of PRUNE1 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 2:185,519,569...185,548,402
Ensembl chr 2:185,520,781...185,548,402
|
|
| G
|
Pten
|
phosphatase and tensin homolog
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of PTEN mRNA
|
CTD |
PMID:16616109 |
|
NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330
|
|
| G
|
Ptgs2
|
prostaglandin-endoperoxide synthase 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of PTGS2
|
CTD |
PMID:28688903 |
|
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
|
|
| G
|
Ptpn14
|
protein tyrosine phosphatase, non-receptor type 14
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of PTPN14 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr13:103,799,473...103,951,708
Ensembl chr13:103,799,494...103,951,708
|
|
| G
|
Rara
|
retinoic acid receptor, alpha
|
increases mutagenesis increases expression multiple interactions
|
ISO EXP
|
Methylnitrosourea results in increased mutagenesis of RARA gene Methylnitrosourea results in increased expression of RARA mRNA Cholecalciferol inhibits the reaction [Methylnitrosourea results in increased expression of RARA mRNA]
|
CTD |
PMID:16868089 PMID:21843606 |
|
NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160
|
|
| G
|
Rb1
|
RB transcriptional corepressor 1
|
increases phosphorylation
|
EXP
|
Methylnitrosourea results in increased phosphorylation of RB1 protein
|
CTD |
PMID:15581186 |
|
NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
|
|
| G
|
Rbck1
|
RANBP2-type and C3HC4-type zinc finger containing 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of RBCK1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:161,249,390...161,266,032
|
|
| G
|
Rbm4
|
RNA binding motif protein 4
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of RBM4 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 1:211,507,845...211,516,907
Ensembl chr 1:211,506,343...211,516,891
|
|
| G
|
Rbm43
|
RNA binding motif protein 43
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of RBM43 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:56,802,384...56,821,371
Ensembl chr 3:56,803,593...56,811,350
|
|
| G
|
Rbp4
|
retinol binding protein 4
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of RBP4 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898
|
|
| G
|
Reg1a
|
regenerating family member 1 alpha
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of REG1 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585
|
|
| G
|
Reg3b
|
regenerating family member 3 beta
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of REG3B mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014
|
|
| G
|
Rela
|
RELA proto-oncogene, NF-kB subunit
|
multiple interactions increases expression decreases expression affects localization affects activity
|
EXP
|
3-aminobenzamide inhibits the reaction [Methylnitrosourea results in decreased expression of RELA protein modified form]; [Methylnitrosourea results in increased expression of NFKBIA protein] which affects the localization of RELA protein; tetramethylpyrazine promotes the reaction [Methylnitrosourea affects the localization of RELA protein] Methylnitrosourea results in increased expression of RELA protein Methylnitrosourea results in decreased expression of RELA protein; Methylnitrosourea results in decreased expression of RELA protein modified form Methylnitrosourea affects the activity of RELA protein
|
CTD |
PMID:15960898 PMID:16098260 PMID:16762860 PMID:17137578 |
|
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
|
|
| G
|
Rfx4
|
regulatory factor X4
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of RFX4 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:20,741,079...20,902,851
|
|
| G
|
Rhbdf2
|
rhomboid 5 homolog 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of RHBDF2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117
|
|
| G
|
Rnase1
|
ribonuclease A family member 1, pancreatic
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of RNASE1 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr15:26,835,436...26,837,145
Ensembl chr15:26,835,463...26,837,248
|
|
| G
|
Rps6kb1
|
ribosomal protein S6 kinase B1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of RPS6KB1 protein; Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of RPS6KB1 protein]; Methylnitrosourea results in increased expression of and results in increased phosphorylation of RPS6KB1 protein; sodium arsenite promotes the reaction [Methylnitrosourea results in increased expression of and results in increased phosphorylation of RPS6KB1 protein]
|
CTD |
PMID:22465879 PMID:38977090 |
|
NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238
|
|
| G
|
RT1-A2
|
RT1 class Ia, locus A2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of RT1-A2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr20:4,872,720...4,876,425
|
|
| G
|
Rxrg
|
retinoid X receptor gamma
|
affects expression
|
EXP
|
Methylnitrosourea affects the expression of RXRG mRNA
|
CTD |
PMID:21843606 |
|
NCBI chr13:82,276,330...82,318,097
Ensembl chr13:82,276,291...82,318,095
|
|
| G
|
S100a3
|
S100 calcium binding protein A3
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of S100A3 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 2:178,331,856...178,387,280
Ensembl chr 2:178,384,578...178,387,280
|
|
| G
|
Scarb2
|
scavenger receptor class B, member 2
|
multiple interactions
|
EXP
|
[Dichlorvos co-treated with Methylnitrosourea] results in increased expression of SCARB2 protein
|
CTD |
PMID:37469457 |
|
NCBI chr14:15,842,583...15,894,123
Ensembl chr14:15,842,515...15,896,671
|
|
| G
|
Scg2
|
secretogranin II
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of SCG2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598
|
|
| G
|
Scn10a
|
sodium voltage-gated channel alpha subunit 10
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of SCN10A mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:128,228,424...128,340,298
|
|
| G
|
Serpine2
|
serpin family E member 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of SERPINE2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202
|
|
| G
|
Sgk1
|
serum/glucocorticoid regulated kinase 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of SGK1 mRNA
|
CTD |
PMID:29110037 |
|
NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
|
|
| G
|
Shc1
|
SHC adaptor protein 1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of SHC1 mRNA; [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of SHC1 protein
|
CTD |
PMID:22465879 |
|
NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914
|
|
| G
|
Slc16a12
|
solute carrier family 16, member 12
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of SLC16A12 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 1:241,597,165...241,674,821
Ensembl chr 1:241,599,066...241,674,743
|
|
| G
|
Slc25a53
|
solute carrier family 25, member 53
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of SLC25A53 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr X:105,099,191...105,111,936
Ensembl chr X:105,099,112...105,113,009
|
|
| G
|
Slc26a4
|
solute carrier family 26 member 4
|
multiple interactions
|
EXP
|
Methylnitrosourea promotes the reaction [Iodine results in increased expression of SLC26A4 mRNA]
|
CTD |
PMID:15922087 |
|
NCBI chr 6:53,835,102...53,873,968
Ensembl chr 6:53,835,110...53,873,216
|
|
| G
|
Slc2a1
|
solute carrier family 2 member 1
|
increases expression multiple interactions
|
EXP
|
Methylnitrosourea results in increased expression of SLC2A1 protein Methylnitrosourea promotes the reaction [sodium arsenite results in increased expression of SLC2A1 protein]
|
CTD |
PMID:38977090 |
|
NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
|
|
| G
|
Slc4a1ap
|
solute carrier family 4 member 1 adaptor protein
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SLC4A1AP mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 6:30,625,931...30,653,859
Ensembl chr 6:30,625,931...30,653,792
|
|
| G
|
Smad4
|
SMAD family member 4
|
increases response to substance
|
ISO
|
SMAD4 gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:12096346 |
|
NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684
|
|
| G
|
Smad7
|
SMAD family member 7
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SMAD7 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849
|
|
| G
|
Smg6
|
SMG6 nonsense mediated mRNA decay factor
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SMG6 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:60,284,628...60,512,738
Ensembl chr10:60,284,628...60,512,733
|
|
| G
|
Snai1
|
snail family transcriptional repressor 1
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of SNAI1 mRNA; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of SNAI1 mRNA]
|
CTD |
PMID:25164625 |
|
NCBI chr 3:176,667,476...176,671,965
|
|
| G
|
Snai2
|
snail family transcriptional repressor 2
|
multiple interactions decreases expression
|
EXP ISO
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of SNAI2 mRNA; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of SNAI2 mRNA] Methylnitrosourea results in decreased expression of SNAI2 mRNA
|
CTD |
PMID:25164625 PMID:27221058 |
|
NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349
|
|
| G
|
Snrnp35
|
small nuclear ribonucleoprotein U11/U12 subunit 35
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SNRNP35 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr12:37,773,052...37,781,635
Ensembl chr12:37,771,759...37,783,908
|
|
| G
|
Snrpc
|
small nuclear ribonucleoprotein polypeptide C
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SNRPC mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr20:5,890,229...5,908,410
Ensembl chr20:5,890,229...5,908,410
|
|
| G
|
Socs3
|
suppressor of cytokine signaling 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of SOCS3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825
|
|
| G
|
Sod2
|
superoxide dismutase 2
|
affects metabolic processing multiple interactions
|
ISO
|
Methylnitrosourea affects the metabolism of SOD2 protein PARP1 protein promotes the reaction [Methylnitrosourea affects the metabolism of SOD2 protein]
|
CTD |
PMID:16052507 |
|
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
|
|
| G
|
Sos1
|
SOS Ras/Rac guanine nucleotide exchange factor 1
|
multiple interactions
|
EXP
|
[Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased expression of SOS1 mRNA
|
CTD |
PMID:22465879 |
|
NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350
|
|
| G
|
Sphk1
|
sphingosine kinase 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of SPHK1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
|
|
| G
|
Spink4
|
serine peptidase inhibitor, Kazal type 4
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of SPINK4 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 5:60,811,899...60,860,823
Ensembl chr 5:60,849,060...60,860,823
|
|
| G
|
Spp1
|
secreted phosphoprotein 1
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of SPP1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
|
|
| G
|
Spry2
|
sprouty RTK signaling antagonist 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of SPRY2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074
|
|
| G
|
Sptan1
|
spectrin, alpha, non-erythrocytic 1
|
increases cleavage
|
EXP
|
Methylnitrosourea results in increased cleavage of SPTAN1 protein
|
CTD |
PMID:17069801 |
|
NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889
|
|
| G
|
Src
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
multiple interactions increases expression
|
EXP
|
Hexachlorobenzene promotes the reaction [Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]]; Hexachlorobenzene promotes the reaction [Methylnitrosourea results in increased phosphorylation of SRC protein]; Methylnitrosourea inhibits the reaction [Hexachlorobenzene promotes the reaction [ESR1 protein binds to SRC protein]]; Methylnitrosourea promotes the reaction [EGFR protein binds to SRC protein]; Methylnitrosourea promotes the reaction [Hexachlorobenzene promotes the reaction [EGFR protein binds to SRC protein]]; Methylnitrosourea promotes the reaction [Hexachlorobenzene results in increased phosphorylation of SRC protein]; Methylnitrosourea results in increased phosphorylation of and results in increased expression of SRC protein Methylnitrosourea results in increased expression of SRC protein
|
CTD |
PMID:22245120 |
|
NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
|
|
| G
|
Stat4
|
signal transducer and activator of transcription 4
|
increases response to substance
|
ISO
|
STAT4 gene mutant form results in increased susceptibility to Methylnitrosourea
|
CTD |
PMID:11418001 |
|
NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346
|
|
| G
|
Stmn1
|
stathmin 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of STMN1 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842
|
|
| G
|
Stmn2
|
stathmin 2
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of STMN2 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335
|
|
| G
|
Syp
|
synaptophysin
|
affects expression
|
EXP
|
Methylnitrosourea affects the expression of SYP protein
|
CTD |
PMID:18155124 |
|
NCBI chr X:17,521,348...17,536,449
Ensembl chr X:17,521,348...17,536,984
|
|
| G
|
Tcrg
|
T cell receptor gamma chain
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of TCRG gene
|
CTD |
PMID:16868089 |
|
NCBI chr17:50,317,679...50,361,771
|
|
| G
|
Terc
|
telomerase RNA component
|
affects response to substance
|
ISO
|
TERC protein affects the susceptibility to Methylnitrosourea
|
CTD |
PMID:14612493 |
|
NCBI chr 2:114,744,148...114,744,535
|
|
| G
|
Tff2
|
trefoil factor 2
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of TFF2 mRNA
|
CTD |
PMID:15240709 |
|
NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,217,121...9,220,979
|
|
| G
|
Tgif1
|
TGFB-induced factor homeobox 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TGIF1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 9:118,194,735...118,204,354
Ensembl chr 9:118,194,444...118,204,442
|
|
| G
|
Thpo
|
thrombopoietin
|
multiple interactions increases expression
|
ISO
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of THPO protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of THPO protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of THPO protein]
|
CTD |
PMID:16822543 |
|
Ensembl chr11:93,686,834...93,693,320
|
|
| G
|
Thra
|
thyroid hormone receptor alpha
|
affects expression
|
EXP
|
Methylnitrosourea affects the expression of THRA mRNA
|
CTD |
PMID:21843606 |
|
NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
|
|
| G
|
Thrb
|
thyroid hormone receptor beta
|
affects expression
|
EXP
|
Methylnitrosourea affects the expression of THRB mRNA
|
CTD |
PMID:21843606 |
|
NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
|
|
| G
|
Thrsp
|
thyroid hormone responsive
|
decreases expression increases expression
|
EXP
|
Methylnitrosourea results in decreased expression of THRSP mRNA Methylnitrosourea results in increased expression of THRSP mRNA
|
CTD |
PMID:16525678 PMID:17341692 |
|
NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827
|
|
| G
|
Thumpd3
|
THUMP domain containing 3
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of THUMPD3 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 4:147,741,288...147,764,254
Ensembl chr 4:147,741,309...147,765,579
|
|
| G
|
Timp1
|
TIMP metallopeptidase inhibitor 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TIMP1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135
|
|
| G
|
Tinagl1
|
tubulointerstitial nephritis antigen-like 1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TINAGL1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 5:147,797,884...147,807,925
Ensembl chr 5:147,797,892...147,807,871
|
|
| G
|
Tkt
|
transketolase
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TKT mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431
|
|
| G
|
Tmem69
|
transmembrane protein 69
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of TMEM69 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 5:135,241,557...135,247,323
Ensembl chr 5:135,241,560...135,247,215
|
|
| G
|
Tnf
|
tumor necrosis factor
|
multiple interactions increases expression
|
ISO EXP
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of TNF protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of TNF protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of TNF protein] Methylnitrosourea results in increased expression of TNF mRNA
|
CTD |
PMID:16822543 PMID:28688903 |
|
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
|
|
| G
|
Tnfrsf11b
|
TNF receptor superfamily member 11B
|
decreases expression
|
EXP
|
Methylnitrosourea results in decreased expression of TNFRSF11B mRNA
|
CTD |
PMID:17341692 |
|
NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
|
|
| G
|
Tnfrsf12a
|
TNF receptor superfamily member 12A
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TNFRSF12A mRNA
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CTD |
PMID:17412507 |
|
NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704
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| G
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Tnip2
|
TNFAIP3 interacting protein 2
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TNIP2 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr14:80,452,936...80,470,141
Ensembl chr14:80,452,845...80,470,992
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| G
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Top2a
|
DNA topoisomerase II alpha
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of TOP2A mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
|
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| G
|
Top3b
|
DNA topoisomerase III beta
|
decreases expression increases expression
|
ISO
|
Methylnitrosourea results in decreased expression of TOP3B mRNA Methylnitrosourea results in increased expression of TOP3B mRNA
|
CTD |
PMID:16616109 PMID:25270620 |
|
NCBI chr11:97,601,223...97,629,678
Ensembl chr11:97,601,231...97,629,597
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| G
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Tor1b
|
torsin family 1, member B
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of TOR1B mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:34,640,929...34,647,023
Ensembl chr 3:34,640,931...34,647,027
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| G
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Tp53
|
tumor protein p53
|
multiple interactions increases stability affects response to substance increases response to substance increases phosphorylation increases expression
|
EXP ISO
|
[Estradiol co-treated with Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA; [Methylnitrosourea co-treated with Progesterone] results in decreased expression of TP53 mRNA; Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TP53 protein] Methylnitrosourea results in increased stability of TP53 protein Methylnitrosourea results in increased expression of and results in increased phosphorylation of TP53 protein; TP53 protein promotes the reaction [Methylnitrosourea results in decreased expression of VRK1 protein] TRP53 protein affects the susceptibility to Methylnitrosourea TRP53 gene mutant form results in increased susceptibility to Methylnitrosourea Methylnitrosourea results in increased phosphorylation of TRP53 protein Butylated Hydroxyanisole inhibits the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]; MAPK8 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]; MGMT protein inhibits the reaction [TRP53 gene mutant form results in increased susceptibility to Methylnitrosourea]; MSH2 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of TRP53 protein]; PARP1 protein affects the reaction [Methylnitrosourea affects the activity of TRP53 protein]; PARP1 protein affects the reaction [Methylnitrosourea affects the expression of TRP53 protein] Methylnitrosourea results in increased expression of TP53 mRNA
|
CTD |
PMID:11536039 PMID:11850828 PMID:12185594 PMID:17412507 PMID:18593901 PMID:20732338 PMID:21285353 PMID:27233451 PMID:28688903 PMID:29110037 More...
|
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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| G
|
Tp53bp1
|
tumor protein p53 binding protein 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of TP53BP1 protein
|
CTD |
PMID:27233451 |
|
NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747
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|
| G
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Tp53inp1
|
tumor protein p53 inducible nuclear protein 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of TRP53INP1 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484
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|
| G
|
Trip6
|
thyroid hormone receptor interactor 6
|
decreases expression
|
ISO
|
Methylnitrosourea results in decreased expression of TRIP6 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr12:25,022,959...25,027,366
Ensembl chr12:25,022,909...25,027,363
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| G
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Tspo
|
translocator protein
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of TSPO mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460
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|
| G
|
Ttk
|
Ttk protein kinase
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of TTK mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664
|
|
| G
|
Twist1
|
twist family bHLH transcription factor 1
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of TWIST1 mRNA; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of TWIST1 mRNA]
|
CTD |
PMID:25164625 |
|
NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965
|
|
| G
|
Tyr
|
tyrosinase
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of TYR gene
|
CTD |
PMID:17174358 |
|
NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
|
|
| G
|
Tyrp1
|
tyrosinase-related protein 1
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of TYRP1 gene
|
CTD |
PMID:17174358 |
|
NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:100,327,125...100,345,657
|
|
| G
|
Ubac2
|
UBA domain containing 2
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of UBAC2 gene
|
CTD |
PMID:16868089 |
|
NCBI chr15:105,366,776...105,514,435
Ensembl chr15:105,366,697...105,514,444
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|
| G
|
Ube2c
|
ubiquitin-conjugating enzyme E2C
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of UBE2C mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678
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| G
|
Ube2j1
|
ubiquitin-conjugating enzyme E2, J1
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of UBE2J1 mRNA
|
CTD |
PMID:17412507 |
|
NCBI chr 5:52,218,807...52,237,805
Ensembl chr 5:52,218,807...52,237,805
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|
| G
|
Upp1
|
uridine phosphorylase 1
|
increases expression decreases expression
|
EXP ISO
|
Methylnitrosourea results in increased expression of UPP1 mRNA Methylnitrosourea results in decreased expression of UPP1 mRNA
|
CTD |
PMID:17412507 PMID:25270620 |
|
NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034
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|
| G
|
Vegfa
|
vascular endothelial growth factor A
|
multiple interactions increases expression
|
ISO EXP
|
Butylated Hydroxytoluene inhibits the reaction [Methylnitrosourea results in increased expression of VEGFA protein]; Freund's Adjuvant inhibits the reaction [Methylnitrosourea results in increased expression of VEGFA protein]; IFNG protein inhibits the reaction [Methylnitrosourea results in increased expression of VEGFA protein] [Methylnitrosourea co-treated with Estradiol] results in increased expression of VEGFA mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of VEGFA mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of VEGFA mRNA
|
CTD |
PMID:16822543 PMID:20732338 |
|
NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
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|
| G
|
Vim
|
vimentin
|
multiple interactions
|
EXP
|
[Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM mRNA; [Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM mRNA]; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of VIM protein]
|
CTD |
PMID:25164625 |
|
NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746
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|
| G
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Vrk1
|
VRK serine/threonine kinase 1
|
decreases expression multiple interactions
|
ISO
|
Methylnitrosourea results in decreased expression of VRK1 protein TP53 protein promotes the reaction [Methylnitrosourea results in decreased expression of VRK1 protein]
|
CTD |
PMID:27233451 |
|
NCBI chr 6:130,679,400...130,746,089
Ensembl chr 6:130,679,515...130,746,752
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|
| G
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Wdr35
|
WD repeat domain 35
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of WDR35 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr 6:37,490,557...37,550,391
Ensembl chr 6:37,490,545...37,550,664
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|
| G
|
Wnt5a
|
Wnt family member 5A
|
increases expression increases expression
|
EXP
|
Methylnitrosourea results in increased expression of WNT5A mRNA N-methyl-N-nitrosourea increases expression of Wnt5a mRNA in colon
|
CTD RGD |
PMID:17341692 PMID:28032729 |
RGD:150530464 |
NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860
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|
| G
|
Xiap
|
X-linked inhibitor of apoptosis
|
decreases response to substance
|
ISO
|
XIAP protein results in decreased susceptibility to Methylnitrosourea
|
CTD |
PMID:12766084 |
|
NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978
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|
| G
|
Xrcc5
|
X-ray repair cross complementing 5
|
increases mutagenesis
|
ISO
|
Methylnitrosourea results in increased mutagenesis of XRCC5 gene
|
CTD |
PMID:16868089 |
|
NCBI chr 9:81,404,507...81,493,293
Ensembl chr 9:81,375,863...81,493,293
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|
| G
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Zeb1
|
zinc finger E-box binding homeobox 1
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of ZEB1 mRNA
|
CTD |
PMID:27221058 |
|
NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745
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|
| G
|
Zfp365
|
zinc finger protein 365
|
increases expression
|
ISO
|
Methylnitrosourea results in increased expression of ZFP365 mRNA
|
CTD |
PMID:25270620 |
|
NCBI chr20:20,665,122...20,688,607
Ensembl chr20:20,665,046...20,690,114
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|
| G
|
Znf8
|
zinc finger protein 8
|
increases expression
|
EXP
|
Methylnitrosourea results in increased expression of ZFP128 mRNA
|
CTD |
PMID:16525678 |
|
NCBI chr 1:82,570,719...82,584,121
Ensembl chr 1:82,570,687...82,584,119
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|
|
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| G
|
H2ax
|
H2A.X variant histone
|
multiple interactions
|
ISO
|
[CYP2A6 protein results in increased metabolism of 4-(N-nitroso-N-methylamino)butyric acid] which results in increased expression of H2AX protein
|
CTD |
PMID:35882637 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
|
|
|
|
| G
|
Ache
|
acetylcholinesterase
|
increases activity
|
ISO
|
dibutylnitrosamine results in increased activity of ACHE protein
|
CTD |
PMID:15881669 |
|
NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
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|
| G
|
Cyb5b
|
cytochrome b5 type B
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine
|
CTD |
PMID:11733072 |
|
NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980
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|
| G
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Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions
|
ISO
|
CYP1A1 protein affects the metabolism of and results in increased activity of dibutylnitrosamine
|
CTD |
PMID:11600130 |
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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|
| G
|
Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
increases hydroxylation
|
EXP
|
CYP2B1 protein results in increased hydroxylation of dibutylnitrosamine
|
CTD |
PMID:8625499 |
|
NCBI chr 1:90,646,098...90,669,762
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine
|
CTD |
PMID:11035158 PMID:11733072 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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|
| G
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Nras
|
NRAS proto-oncogene, GTPase
|
increases activity
|
EXP
|
dibutylnitrosamine results in increased activity of NRAS
|
CTD |
PMID:3040652 |
|
NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543
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|
| G
|
Parp1
|
poly (ADP-ribose) polymerase 1
|
increases cleavage
|
ISO
|
dibutylnitrosamine results in increased cleavage of PARP1 protein
|
CTD |
PMID:17929238 |
|
NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
|
|
| G
|
Por
|
cytochrome p450 oxidoreductase
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine
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CTD |
PMID:11035158 PMID:11733072 |
|
NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
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|
| G
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Tp53
|
tumor protein p53
|
increases response to substance
|
ISO
|
TRP53 gene mutant form results in increased susceptibility to dibutylnitrosamine
|
CTD |
PMID:12706858 |
|
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
|
|
|
|
| G
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Cyb5a
|
cytochrome b5 type A
|
multiple interactions
|
ISO
|
CYB5A protein promotes the reaction [CYP2A6 protein results in increased activity of N-nitroso(di-n-propyl)amine]; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine]
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CTD |
PMID:15728263 |
|
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094 Ensembl chr18:14,453,966...14,455,094
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|
| G
|
Cyb5b
|
cytochrome b5 type B
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine
|
CTD |
PMID:11733072 |
|
NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980
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|
| G
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Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
affects metabolic processing increases hydroxylation decreases nitrosation
|
EXP
|
CYP2B1 protein affects the metabolism of N-nitroso(di-n-propyl)amine CYP2B1 protein results in increased hydroxylation of N-nitroso(di-n-propyl)amine CYP2B1 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine
|
CTD |
PMID:8625499 PMID:10910959 |
|
NCBI chr 1:90,646,098...90,669,762
|
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| G
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Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
affects metabolic processing
|
ISO
|
CYP2B6 protein affects the metabolism of N-nitroso(di-n-propyl)amine
|
CTD |
PMID:10910959 |
|
NCBI chr 1:90,780,468...90,859,852
|
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| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions increases activity affects metabolic processing
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine] CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine
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CTD |
PMID:10910959 PMID:11035158 PMID:11733072 PMID:15728263 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
decreases nitrosation affects metabolic processing
|
ISO
|
CYP3A4 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine CYP3A4 protein affects the metabolism of N-nitroso(di-n-propyl)amine
|
CTD |
PMID:10910959 |
|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
|
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| G
|
Por
|
cytochrome p450 oxidoreductase
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine
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CTD |
PMID:11035158 PMID:11733072 |
|
NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809
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|
|
|
| G
|
Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
increases metabolic processing
|
ISO
|
CYP2E1 protein results in increased metabolism of N-nitrosodiethanolamine
|
CTD |
PMID:18616954 |
|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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| G
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H2ax
|
H2A.X variant histone
|
increases phosphorylation
|
EXP
|
N-nitrosodiethanolamine results in increased phosphorylation of H2AX protein
|
CTD |
PMID:37527026 |
|
NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
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|
| G
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Mki67
|
marker of proliferation Ki-67
|
increases expression
|
EXP
|
N-nitrosodiethanolamine results in increased expression of MKI67 protein
|
CTD |
PMID:37527026 |
|
NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
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|
|
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| G
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A1bg
|
alpha-1-B glycoprotein
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of A1BG mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of A1BG mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of A1BG mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of A1BG mRNA]
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CTD |
PMID:18164116 PMID:22129741 |
|
NCBI chr 7:94,383,333...94,387,922
Ensembl chr 7:94,383,333...94,387,496
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|
| G
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A2m
|
alpha-2-macroglobulin
|
multiple interactions increases expression decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of A2M mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of A2M protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of A2M promoter; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of A2M mRNA; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of A2M mRNA] Diethylnitrosamine results in increased expression of A2M mRNA; Diethylnitrosamine results in increased expression of A2M protein
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CTD |
PMID:20360939 PMID:20935162 PMID:25374375 PMID:27565560 PMID:28943392 PMID:29698782 More...
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|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868
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|
| G
|
A3galt2
|
alpha 1,3-galactosyltransferase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of A3GALT2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:146,385,725...146,398,156
Ensembl chr 5:146,385,746...146,400,043
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|
| G
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Aaas
|
aladin WD repeat nucleoporin
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of AAAS mRNA
|
CTD |
PMID:21607683 |
|
NCBI chr 7:135,342,901...135,362,545
Ensembl chr 7:135,342,901...135,362,545
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|
| G
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Aadat
|
aminoadipate aminotransferase
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of AADAT mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540
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|
| G
|
Aanat
|
aralkylamine N-acetyltransferase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AANAT mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:102,323,647...102,330,639
Ensembl chr10:102,326,135...102,330,635
|
|
| G
|
Abca3
|
ATP binding cassette subfamily A member 3
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ABCA3 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABCA3 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285
|
|
| G
|
Abca5
|
ATP binding cassette subfamily A member 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCA5 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,739,610...95,808,424
|
|
| G
|
Abcb11
|
ATP binding cassette subfamily B member 11
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCB11 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ABCB11 mRNA Diethylnitrosamine results in decreased expression of ABCB11 mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
|
|
| G
|
Abcb1a
|
ATP binding cassette subfamily B member 1A
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Cisplatin] results in increased expression of ABCB1 protein; [Diethylnitrosamine co-treated with Epirubicin] results in increased expression of ABCB1 protein; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCB1A mRNA Diethylnitrosamine results in increased expression of ABCB1A mRNA Diethylnitrosamine results in increased expression of ABCB1 protein; Diethylnitrosamine results in increased expression of ABCB1A mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ABCB1A mRNA
|
CTD |
PMID:11818250 PMID:19638242 PMID:22129741 PMID:24535843 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
|
|
| G
|
Abcb1b
|
ATP-binding cassette, sub-family B member 1B
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ABCB1B mRNA [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCB1B mRNA
|
CTD |
PMID:17602206 PMID:22129741 |
|
NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567
|
|
| G
|
Abcb4
|
ATP binding cassette subfamily B member 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCB4 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 4:26,106,895...26,164,440
|
|
| G
|
Abcc2
|
ATP binding cassette subfamily C member 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA; [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA
|
CTD |
PMID:18544905 PMID:23665939 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
|
|
| G
|
Abcc3
|
ATP binding cassette subfamily C member 3
|
multiple interactions increases expression
|
ISO EXP
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA Diethylnitrosamine results in increased expression of ABCC3 mRNA [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ABCC3 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ABCC3 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCC3 mRNA
|
CTD |
PMID:18648771 PMID:19638242 PMID:19690152 PMID:20360939 PMID:22129741 |
|
NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494
|
|
| G
|
Abcc4
|
ATP binding cassette subfamily C member 4
|
multiple interactions
|
ISO EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ABCC4 mRNA; [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of ABCC4 mRNA [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCC4 mRNA
|
CTD |
PMID:19690152 PMID:22129741 PMID:24535843 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
|
|
| G
|
Abcc5
|
ATP binding cassette subfamily C member 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCC5 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
|
|
| G
|
Abcc6
|
ATP binding cassette subfamily C member 6
|
multiple interactions decreases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC6 mRNA Diethylnitrosamine results in decreased expression of ABCC6 mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCC6 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC6 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ABCC6 mRNA
|
CTD |
PMID:17602206 PMID:17917374 PMID:18544905 PMID:19638242 PMID:28943392 |
|
NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895
|
|
| G
|
Abcc9
|
ATP binding cassette subfamily C member 9
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ABCC9 mRNA [Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC9 mRNA
|
CTD |
PMID:17917374 PMID:18164116 |
|
NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348
|
|
| G
|
Abcd1
|
ATP binding cassette subfamily D member 1
|
multiple interactions
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCD1 mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCD1 mRNA
|
CTD |
PMID:17602206 PMID:17917374 |
|
NCBI chr X:156,579,669...156,601,448
Ensembl chr X:156,579,785...156,601,446
|
|
| G
|
Abcd2
|
ATP binding cassette subfamily D member 2
|
multiple interactions increases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCD2 mRNA Diethylnitrosamine results in increased expression of ABCD2 mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:124,142,595...124,191,202
|
|
| G
|
Abce1
|
ATP binding cassette subfamily E member 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ABCE1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of ABCE1 promoter
|
CTD |
PMID:25374375 |
|
NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819
|
|
| G
|
Abcf2
|
ATP binding cassette subfamily F member 2
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCF2 mRNA [Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCF2 mRNA
|
CTD |
PMID:17602206 PMID:17917374 |
|
NCBI chr 4:11,485,865...11,500,067
Ensembl chr 4:11,487,395...11,500,053
|
|
| G
|
Abcg1
|
ATP binding cassette subfamily G member 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ABCG1 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCG1 mRNA
|
CTD |
PMID:17602206 PMID:18164116 |
|
NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563
|
|
| G
|
Abcg4
|
ATP binding cassette subfamily G member 4
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr 8:53,508,005...53,525,314
Ensembl chr 8:53,508,005...53,523,571
|
|
| G
|
Abcg5
|
ATP binding cassette subfamily G member 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCG5 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG5 mRNA
|
CTD |
PMID:17602206 PMID:22129741 |
|
NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376
|
|
| G
|
Abcg8
|
ATP binding cassette subfamily G member 8
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG8 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730
|
|
| G
|
Abhd1
|
abhydrolase domain containing 1
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABHD1 mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464
|
|
| G
|
Abhd12
|
abhydrolase domain containing 12, lysophospholipase
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ABHD12 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:160,119,724...160,179,959
Ensembl chr 3:160,119,724...160,179,969
|
|
| G
|
Abhd15
|
abhydrolase domain containing 15
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ABHD15 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr10:62,861,335...62,866,726
Ensembl chr10:62,861,317...62,868,540
|
|
| G
|
Abhd2
|
abhydrolase domain containing 2, acylglycerol lipase
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ABHD2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674
|
|
| G
|
Abhd5
|
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ABHD5 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947
|
|
| G
|
Abhd8
|
abhydrolase domain containing 8
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABHD8 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr16:18,178,441...18,185,178
Ensembl chr16:18,178,441...18,191,638
|
|
| G
|
Abi2
|
abl-interactor 2
|
multiple interactions increases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABI2 mRNA Diethylnitrosamine results in increased expression of ABI2 mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597
|
|
| G
|
Abi3bp
|
ABI family member 3 binding protein
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ABI3BP mRNA Diethylnitrosamine results in increased expression of ABI3BP mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr11:57,381,282...57,597,989
Ensembl chr11:57,381,422...57,598,120
|
|
| G
|
Ablim3
|
actin binding LIM protein family, member 3
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ABLIM3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710
|
|
| G
|
Abr
|
ABR activator of RhoGEF and GTPase
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ABR gene
|
CTD |
PMID:23968726 |
|
NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467
|
|
| G
|
Abtb1
|
ankyrin repeat and BTB domain containing 1
|
multiple interactions affects response to substance
|
ISO
|
[ABTB1 protein affects the susceptibility to Diethylnitrosamine] which affects the expression of GPT protein; [ABTB1 protein affects the susceptibility to Diethylnitrosamine] which affects the expression of IL1B protein
|
CTD |
PMID:38866194 |
|
NCBI chr 4:122,856,558...122,862,895
Ensembl chr 4:122,856,564...122,862,789
|
|
| G
|
Abtb2
|
ankyrin repeat and BTB domain containing 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ABTB2 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABTB2 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 3:110,409,672...110,563,488
Ensembl chr 3:110,409,627...110,563,487
|
|
| G
|
Acaa1b
|
acetyl-Coenzyme A acyltransferase 1B
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ACAA1B mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569
|
|
| G
|
Acaa2
|
acetyl-CoA acyltransferase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ACAA2 mRNA
|
CTD |
PMID:14656948 |
|
NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420
|
|
| G
|
Acaca
|
acetyl-CoA carboxylase alpha
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ACACA mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888
|
|
| G
|
Acacb
|
acetyl-CoA carboxylase beta
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACACB mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214
|
|
| G
|
Acadl
|
acyl-CoA dehydrogenase, long chain
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ACADL mRNA
|
CTD |
PMID:11323195 |
|
NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164
|
|
| G
|
Acadm
|
acyl-CoA dehydrogenase medium chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACADM mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864
|
|
| G
|
Acan
|
aggrecan
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACAN mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
|
|
| G
|
Acap2
|
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACAP2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr11:83,043,442...83,159,105
Ensembl chr11:83,043,511...83,159,107
|
|
| G
|
Acat1
|
acetyl-CoA acetyltransferase 1
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA
|
CTD |
PMID:18253720 |
|
NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042
|
|
| G
|
Acat2
|
acetyl-CoA acetyltransferase 2
|
increases expression decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ACAT2 mRNA Diethylnitrosamine results in decreased expression of ACAT3 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACAT2 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:20387270 |
|
NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095
|
|
| G
|
Acbd3
|
acyl-CoA binding domain containing 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACBD3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr13:94,987,643...95,016,356
Ensembl chr13:94,987,541...95,016,355
|
|
| G
|
Acbd4
|
acyl-CoA binding domain containing 4
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ACBD4 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr10:88,548,146...88,558,588
Ensembl chr10:88,548,158...88,558,587
|
|
| G
|
Acbd5
|
acyl-CoA binding domain containing 5
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ACBD5 mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr17:90,114,250...90,156,286
Ensembl chr17:90,114,375...90,156,286
|
|
| G
|
Ace
|
angiotensin I converting enzyme
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACE mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942
|
|
| G
|
Acer3
|
alkaline ceramidase 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACER3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:161,915,397...162,017,802
Ensembl chr 1:161,915,397...162,017,912
|
|
| G
|
Acmsd
|
aminocarboxymuconate semialdehyde decarboxylase
|
multiple interactions
|
EXP
|
[Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of ACMSD mRNA
|
CTD |
PMID:15833021 |
|
NCBI chr13:41,752,894...41,798,427
Ensembl chr13:41,752,875...41,798,427
|
|
| G
|
Aco2
|
aconitase 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ACO2 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ACO2 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892
|
|
| G
|
Acot1
|
acyl-CoA thioesterase 1
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of ACOT1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACOT1 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749
|
|
| G
|
Acot2
|
acyl-CoA thioesterase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ACOT2 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACOT2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACOT2 mRNA
|
CTD |
PMID:17602206 PMID:20360939 PMID:22129741 |
|
NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502
|
|
| G
|
Acot3
|
acyl-CoA thioesterase 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACOT3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 6:109,413,617...109,419,840
Ensembl chr 6:109,413,534...109,421,427 Ensembl chr 6:109,413,534...109,421,427
|
|
| G
|
Acot4
|
acyl-CoA thioesterase 4
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACOT4 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138
|
|
| G
|
Acot5
|
acyl-CoA thioesterase 5
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACOT5 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 6:109,433,062...109,439,846
Ensembl chr 6:109,453,391...109,461,035 Ensembl chr 6:109,453,391...109,461,035
|
|
| G
|
Acot7
|
acyl-CoA thioesterase 7
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACOT7 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033
|
|
| G
|
Acot9
|
acyl-CoA thioesterase 9
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ACOT9 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205
|
|
| G
|
Acox1
|
acyl-CoA oxidase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACOX1 mRNA; [Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of ACOX1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA
|
CTD |
PMID:17602206 PMID:18253720 PMID:18775883 PMID:30298849 |
|
NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
|
|
| G
|
Acox2
|
acyl-CoA oxidase 2
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACOX2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ACOX2 mRNA Diethylnitrosamine results in decreased expression of ACOX2 mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392
|
|
| G
|
Acp3
|
acid phosphatase 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACP3 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACP3 mRNA
|
CTD |
PMID:17602206 PMID:22129741 |
|
NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033
|
|
| G
|
Acp5
|
acid phosphatase 5, tartrate resistant
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ACP5 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ACP5 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
|
|
| G
|
Acsl1
|
acyl-CoA synthetase long-chain family member 1
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of ACSL1 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ACSL1 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023
|
|
| G
|
Acsl3
|
acyl-CoA synthetase long-chain family member 3
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACSL3 mRNA Diethylnitrosamine results in increased expression of ACSL3 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097
|
|
| G
|
Acsl4
|
acyl-CoA synthetase long-chain family member 4
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ACSL4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:110,739,633...110,803,416
Ensembl chr X:110,739,648...110,803,261
|
|
| G
|
Acsl5
|
acyl-CoA synthetase long-chain family member 5
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of ACSL5 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ACSL5 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943
|
|
| G
|
Acsm1
|
acyl-CoA synthetase medium-chain family member 1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ACSM1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217
|
|
| G
|
Acsm2
|
acyl-CoA synthetase medium-chain family member 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ACSM2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM2 mRNA
|
CTD |
PMID:22129741 PMID:28943392 |
|
NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:183,347,705...183,386,453
|
|
| G
|
Acsm3
|
acyl-CoA synthetase medium-chain family member 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SAH mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of SAH mRNA
|
CTD |
PMID:17602206 PMID:28943392 |
|
NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437
|
|
| G
|
Acsm5
|
acyl-CoA synthetase medium-chain family member 5
|
multiple interactions decreases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSM5 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM5 mRNA] Diethylnitrosamine results in decreased expression of ACSM5 mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 1:183,302,241...183,328,175
Ensembl chr 1:183,294,105...183,329,925
|
|
| G
|
Acss1
|
acyl-CoA synthetase short-chain family member 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSS1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748
|
|
| G
|
Acta2
|
actin alpha 2, smooth muscle
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of ACTA2 protein salvianolic acid B affects the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of ACTA2 protein]]; salvianolic acid B inhibits the reaction [Diethylnitrosamine results in increased expression of ACTA2 protein]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in increased expression of ACTA2 protein]
|
CTD |
PMID:18522880 PMID:19822196 PMID:26589970 PMID:33290806 |
|
NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
|
|
| G
|
Actg1
|
actin, gamma 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ACTG1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951
|
|
| G
|
Actg2
|
actin gamma 2, smooth muscle
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ACTG2 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 4:117,579,513...117,604,379
Ensembl chr 4:117,579,514...117,604,295
|
|
| G
|
Actn3
|
actinin alpha 3
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ACTN3 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 1:211,588,473...211,604,401
Ensembl chr 1:211,588,474...211,604,401
|
|
| G
|
Actr10
|
actin related protein 10
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ACTR10 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:95,182,082...95,208,325
Ensembl chr 6:95,182,111...95,209,021
|
|
| G
|
Acvr2b
|
activin A receptor type 2B
|
multiple interactions
|
EXP
|
[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of SCGB2A2 protein
|
CTD |
PMID:20935162 |
|
NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:128,016,526...128,048,171
|
|
| G
|
Acvrl1
|
activin A receptor like type 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACVRL1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305
|
|
| G
|
Acy3
|
aminoacylase 3
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ACY3 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 1:210,709,238...210,715,258
Ensembl chr 1:210,709,294...210,715,633
|
|
| G
|
Adam23
|
ADAM metallopeptidase domain 23
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ADAM23 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 9:72,356,479...72,503,545
Ensembl chr 9:72,356,479...72,503,545
|
|
| G
|
Adam7
|
ADAM metallopeptidase domain 7
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADAM7 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr15:47,009,176...47,057,581
Ensembl chr15:47,009,176...47,057,581
|
|
| G
|
Adamdec1
|
ADAM-like, decysin 1
|
multiple interactions decreases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ADAMDEC1 mRNA Diethylnitrosamine results in decreased expression of ADAMDEC1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr15:47,076,011...47,097,065
Ensembl chr15:47,076,019...47,097,065
|
|
| G
|
Adamts1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ADAMTS1 mRNA
|
CTD |
PMID:12771043 |
|
NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390
|
|
| G
|
Adamts2
|
ADAM metallopeptidase with thrombospondin type 1 motif, 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ADAMTS2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483
|
|
| G
|
Adamts9
|
ADAM metallopeptidase with thrombospondin type 1 motif, 9
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ADAMTS9 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876
|
|
| G
|
Adamtsl4
|
ADAMTS-like 4
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADAMTSL4 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ADAMTSL4 mRNA
|
CTD |
PMID:17602206 PMID:24535843 |
|
NCBI chr 2:185,924,582...185,936,039
Ensembl chr 2:185,924,594...185,935,796
|
|
| G
|
Adcy2
|
adenylate cyclase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADCY2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645
|
|
| G
|
Adcy3
|
adenylate cyclase 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADCY3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173
|
|
| G
|
Adcy8
|
adenylate cyclase 8
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADCY8 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:98,306,464...98,555,038
|
|
| G
|
Adgrb2
|
adhesion G protein-coupled receptor B2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:147,581,573...147,646,726
Ensembl chr 5:147,611,580...147,646,726
|
|
| G
|
Adgrb3
|
adhesion G protein-coupled receptor B3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 9:34,917,474...35,645,350
Ensembl chr 9:34,917,474...35,644,811
|
|
| G
|
Adgrg1
|
adhesion G protein-coupled receptor G1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124
|
|
| G
|
Adgrg2
|
adhesion G protein-coupled receptor G2
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ADGRG2 mRNA Diethylnitrosamine results in decreased expression of ADGRG2 mRNA
|
CTD |
PMID:18164116 PMID:20360939 PMID:22129741 |
|
NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331
|
|
| G
|
Adgrg6
|
adhesion G protein-coupled receptor G6
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ADGRG6 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:10,633,004...10,774,685
Ensembl chr 1:10,631,829...10,774,023
|
|
| G
|
Adgrv1
|
adhesion G protein-coupled receptor V1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ADGRV1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:13,067,149...13,647,407
Ensembl chr 2:13,067,150...13,647,372
|
|
| G
|
Adh1c
|
alcohol dehydrogenase 1C (class I), gamma polypeptide
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADH1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291
|
|
| G
|
Adh4
|
alcohol dehydrogenase 4 (class II), pi polypeptide
|
decreases expression
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of ADH4 mRNA
|
CTD |
PMID:19638242 PMID:21527772 PMID:24535843 |
|
NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879
|
|
| G
|
Adh6
|
alcohol dehydrogenase 6 (class V)
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ADH6 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914
|
|
| G
|
Adh7
|
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ADH7 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691
|
|
| G
|
Adhfe1
|
alcohol dehydrogenase, iron containing, 1
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of ADHFE1 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ADHFE1 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835
|
|
| G
|
Adi1
|
acireductone dioxygenase 1
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ADI1 mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855
|
|
| G
|
Adk
|
adenosine kinase
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of ADK mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADK mRNA
|
CTD |
PMID:17602206 PMID:20360939 |
|
NCBI chr15:2,912,543...3,295,745
Ensembl chr15:2,912,544...3,295,745
|
|
| G
|
Adra1b
|
adrenoceptor alpha 1B
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of ADRA1B mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ADRA1B mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347
|
|
| G
|
Adra1d
|
adrenoceptor alpha 1D
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ADRA1D mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331
|
|
| G
|
Adrb3
|
adrenoceptor beta 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADRB3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420
|
|
| G
|
Adsl
|
adenylosuccinate lyase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADSL mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872
|
|
| G
|
Adtrp
|
androgen-dependent TFPI-regulating protein
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ADTRP mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622
|
|
| G
|
Aebp1
|
AE binding protein 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of AEBP1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843
|
|
| G
|
Aebp2
|
AE binding protein 2
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AEBP2 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422
|
|
| G
|
Aen
|
apoptosis enhancing nuclease
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of AEN mRNA
|
CTD |
PMID:19100860 PMID:21607683 |
|
NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898
|
|
| G
|
Afm
|
afamin
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of AFM mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AFM mRNA Diethylnitrosamine results in decreased expression of AFM mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AFM mRNA]
|
CTD |
PMID:17942915 PMID:19638242 PMID:28943392 |
|
NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039
|
|
| G
|
Afp
|
alpha-fetoprotein
|
decreases expression increases expression multiple interactions affects expression
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of AFP mRNA N-nitrosodiethylamine increases expression of Afp protein in serum in rats Diethylnitrosamine results in increased expression of AFP mRNA; Diethylnitrosamine results in increased expression of AFP protein [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Diethylnitrosamine] results in increased expression of AFP mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of AFP mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AFP mRNA; Diethylnitrosamine promotes the reaction [Carbon Tetrachloride results in increased expression of AFP mRNA]; Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Losartan inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Sorafenib inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] Diethylnitrosamine results in increased expression of AFP mRNA; Diethylnitrosamine results in increased expression of AFP protein; Diethylnitrosamine results in increased expression of AFP protein alternative form 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP protein; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of AFP protein; alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; alogliptin promotes the reaction [taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]]; brucine inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; carfilzomib inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; citral inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Dahuang Zhechong pill inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; formylchromone analog inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; FR 118487 inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of AFP protein]; Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; myrrh resin analog inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP protein]; piperlongumine inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of AFP protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AFP protein]; Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Rotenone inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein]; Silymarin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; taxifolin promotes the reaction [alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]]; thymoquinone inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein alternative form]; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] Diethylnitrosamine affects the expression of AFP mRNA
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CTD RGD |
PMID:11818250 PMID:15766596 PMID:19394651 PMID:19446540 PMID:19822196 PMID:21391223 PMID:21527772 PMID:23288052 PMID:24012840 PMID:24060683 PMID:24535843 PMID:24632418 PMID:24954034 PMID:27565560 PMID:28414157 PMID:28693887 PMID:28935427 PMID:29458170 PMID:29698782 PMID:29859236 PMID:29923357 PMID:30779474 PMID:32302048 PMID:33398415 PMID:33840231 PMID:35113675 PMID:35437842 PMID:36731809 PMID:25999787 More...
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RGD:152177911 |
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
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| G
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Agap2
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ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AGAP2 mRNA
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CTD |
PMID:20360939 |
|
NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:64,782,612...64,799,640
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| G
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Agfg1
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ArfGAP with FG repeats 1
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of AGFG1 mRNA
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CTD |
PMID:24535843 |
|
NCBI chr 9:91,572,962...91,630,688
Ensembl chr 9:91,573,157...91,626,910
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| G
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Agmat
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agmatinase
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decreases expression
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ISO
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Diethylnitrosamine results in decreased expression of AGMAT mRNA
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CTD |
PMID:24535843 |
|
NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:159,343,160...159,357,299
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| G
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Agr3
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anterior gradient 3, protein disulphide isomerase family member
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decreases expression
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ISO
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Diethylnitrosamine results in decreased expression of AGR3 mRNA
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CTD |
PMID:21527772 |
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NCBI chr 6:58,370,701...58,393,944
Ensembl chr 6:58,370,701...58,399,859
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| G
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Agt
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angiotensinogen
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multiple interactions
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ISO EXP
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IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA] [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGT mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AGT mRNA
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CTD |
PMID:17602206 PMID:18691550 PMID:28943392 |
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NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
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| G
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Agtpbp1
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ATP/GTP binding carboxypeptidase 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AGTPBP1 mRNA
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CTD |
PMID:28943392 |
|
NCBI chr17:5,092,108...5,244,414
Ensembl chr17:5,126,146...5,244,420
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| G
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Agtr1a
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angiotensin II receptor, type 1a
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGTR1A mRNA
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CTD |
PMID:17602206 |
|
NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
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| G
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Agtrap
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angiotensin II receptor-associated protein
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGTRAP mRNA
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CTD |
PMID:17602206 |
|
NCBI chr 5:163,790,565...163,802,174
Ensembl chr 5:163,791,887...163,802,174
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| G
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Agxt
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alanine--glyoxylate aminotransferase
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increases expression decreases expression multiple interactions
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ISO EXP
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Diethylnitrosamine results in increased expression of AGXT mRNA Diethylnitrosamine results in decreased expression of AGXT mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AGXT mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AGXT mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of AGXT mRNA; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGXT mRNA]
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CTD |
PMID:17942915 PMID:18164116 PMID:19041683 PMID:24535843 PMID:28943392 |
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NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:101,122,793...101,132,745
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| G
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Ahcy
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adenosylhomocysteinase
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decreases expression multiple interactions
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EXP ISO
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Diethylnitrosamine results in decreased expression of AHCY mRNA [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of AHCY mRNA
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CTD |
PMID:20360939 PMID:29127188 |
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NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587
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| G
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Ahnak
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AHNAK nucleoprotein
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increases expression
|
EXP
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Diethylnitrosamine results in increased expression of AHNAK mRNA
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CTD |
PMID:19638242 |
|
NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675
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| G
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Ahr
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aryl hydrocarbon receptor
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decreases response to substance increases expression decreases expression multiple interactions
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ISO EXP
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AHR protein results in decreased susceptibility to Diethylnitrosamine Diethylnitrosamine results in increased expression of AHR mRNA Diethylnitrosamine results in decreased expression of AHR protein [Diethylnitrosamine co-treated with Hexachlorobenzene] results in increased expression of AHR protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AHR protein; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of TP53 protein]] [Piperonyl Butoxide co-treated with Diethylnitrosamine] results in increased expression of AHR mRNA; AHR protein affects the reaction [Diethylnitrosamine affects the expression of APAF1 mRNA]; AHR protein affects the reaction [Diethylnitrosamine results in increased expression of IL6 protein]; AHR protein affects the reaction [Diethylnitrosamine results in increased expression of TNF mRNA]; AHR protein affects the reaction [Diethylnitrosamine results in increased expression of TNF protein]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of APAF1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2C mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNMT1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of HDAC1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of MCM7 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of SIRT1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRP53 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRP73 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC25B mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of SERPINE1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of TGFB2 mRNA]; AHR protein promotes the reaction [Diethylnitrosamine results in increased expression of IL6 mRNA]; Diethylnitrosamine promotes the reaction [AHR protein binds to CYP1A1 promoter] Diethylnitrosamine results in decreased expression of AHR mRNA
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CTD |
PMID:15459018 PMID:15535986 PMID:18282651 PMID:19690152 PMID:19996281 PMID:20935162 PMID:22129741 PMID:22687989 PMID:26219504 PMID:27565560 More...
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|
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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|
| G
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Ahrr
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aryl-hydrocarbon receptor repressor
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AHRR mRNA
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CTD |
PMID:18164116 |
|
NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866
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| G
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Ahsa1
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activator of Hsp90 ATPase activity 1
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of AHSA1 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AHSA1 mRNA]
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CTD |
PMID:17942915 |
|
NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595
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| G
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Aifm3
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AIF family member 3
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decreases expression
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ISO
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Diethylnitrosamine results in decreased expression of AIFM3 mRNA
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CTD |
PMID:24535843 |
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NCBI chr11:97,009,100...97,030,601
Ensembl chr11:97,008,426...97,023,334
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| G
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Ajuba
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ajuba LIM protein
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of AJUBA mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AJUBA mRNA
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CTD |
PMID:24535843 |
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NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042
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|
| G
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Ak4
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adenylate kinase 4
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decreases expression multiple interactions
|
EXP
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Diethylnitrosamine results in decreased expression of AK4 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AK4 mRNA
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CTD |
PMID:19638242 PMID:28943392 |
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NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401
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|
| G
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Akap8
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A-kinase anchoring protein 8
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increases expression
|
EXP
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Diethylnitrosamine results in increased expression of AKAP8 mRNA
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CTD |
PMID:20360939 |
|
NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900
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|
| G
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Akap9
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A-kinase anchoring protein 9
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multiple interactions increases expression
|
EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AKAP9 mRNA Diethylnitrosamine results in increased expression of AKAP9 mRNA
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CTD |
PMID:19041683 PMID:20360939 |
|
NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338
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|
| G
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Akr1a1
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aldo-keto reductase family 1 member A1
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multiple interactions increases response to substance
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EXP ISO
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AKR1A1 mRNA AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine [AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine] which results in decreased abundance of Ascorbic Acid; AKR1A1 gene mutant form promotes the reaction [Diethylnitrosamine results in decreased abundance of Ascorbic Acid]
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CTD |
PMID:17602206 PMID:32805337 |
|
NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035
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|
| G
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Akr1b1
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aldo-keto reductase family 1 member B1
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increases expression
|
EXP ISO
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Diethylnitrosamine results in increased expression of AKR1B1 mRNA
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CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315
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|
| G
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Akr1b10
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aldo-keto reductase family 1 member B10
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AKR1B10 mRNA
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CTD |
PMID:14656948 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
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|
| G
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Akr1b15
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aldo-keto reductase family 1 member B15
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multiple interactions increases expression
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR1B8 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR1B8 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AKR1B8 mRNA Diethylnitrosamine results in increased expression of AKR1B8 mRNA; Diethylnitrosamine results in increased expression of AKR1B8 protein
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CTD |
PMID:11565795 PMID:18164116 PMID:19638242 PMID:22129741 PMID:28943392 |
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NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
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|
| G
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Akr1b7
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aldo-keto reductase family 1, member B7
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increases expression multiple interactions
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EXP ISO
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Diethylnitrosamine results in increased expression of AKR1B7 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AKR1B7 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR1B7 mRNA
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CTD |
PMID:19638242 PMID:24535843 PMID:28943392 |
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NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909
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|
| G
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Akr1b8-ps1
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aldo-keto reductase family 1, member B8, pseudogene 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR1B8-PS1 mRNA
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CTD |
PMID:28943392 |
|
NCBI chr 1:240,221,768...240,222,776
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|
| G
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Akr1c1
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aldo-keto reductase family 1, member C1
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AKR1C6 mRNA
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CTD |
PMID:28943392 |
|
NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247
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|
| G
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Akr1c12
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aldo-keto reductase family 1, member C12
|
multiple interactions
|
EXP
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[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of AKR1C12 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AKR1C12 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR1C12 mRNA
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CTD |
PMID:14656948 PMID:16158176 PMID:28943392 |
|
NCBI chr17:70,955,288...70,971,412
Ensembl chr17:70,955,294...70,971,431
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|
| G
|
Akr1c3
|
aldo-keto reductase family 1, member C3
|
multiple interactions increases expression
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EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA Diethylnitrosamine results in increased expression of AKR1C18 mRNA
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CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438
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|
| G
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Akr1c3l1
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aldo-keto reductase family 1 member C3-like 1
|
multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AKR1C3L1 mRNA
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CTD |
PMID:28943392 |
|
NCBI chr17:70,745,496...70,791,411
Ensembl chr17:70,745,496...70,791,322
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|
| G
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Akr1c8
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aldo-keto reductase family 1 member C8
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR1CL mRNA
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CTD |
PMID:28943392 |
|
NCBI chr17:71,091,398...71,117,985
Ensembl chr17:71,083,080...71,117,957
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|
| G
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Akr1d1
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aldo-keto reductase family 1, member D1
|
decreases expression
|
EXP
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Diethylnitrosamine results in decreased expression of AKR1D1 mRNA
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CTD |
PMID:20360939 |
|
NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540
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|
| G
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Akr1e2
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aldo-keto reductase family 1, member E2
|
multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR1E1 mRNA
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CTD |
PMID:18164116 |
|
NCBI chr17:70,645,835...70,660,366
Ensembl chr17:70,645,869...70,660,360
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|
| G
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Akr7a3
|
aldo-keto reductase family 7 member A3
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multiple interactions increases expression decreases expression
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR7A3 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of AKR7A3 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of AKR7A3 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of AKR7A3 mRNA; [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of AKR7A3 mRNA; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of AKR7A3 mRNA] Diethylnitrosamine results in increased expression of AKR7A3 mRNA Diethylnitrosamine results in decreased expression of AKR7A3 mRNA
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CTD |
PMID:11323195 PMID:18164116 PMID:18754104 PMID:19638242 PMID:20033131 PMID:21813463 PMID:22129741 PMID:22467020 PMID:22687989 PMID:28943392 More...
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|
NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153
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|
| G
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Akt1
|
AKT serine/threonine kinase 1
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multiple interactions increases expression increases phosphorylation
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ISO EXP
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CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein]; Diethylnitrosamine inhibits the reaction [Cholic Acid results in increased activity of and results in increased phosphorylation of AKT1 protein] N-nitrosodiethylamine increases expression of Akt1 protein in liver in rats [Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of and results in increased phosphorylation of AKT1 protein; [Sorafenib co-treated with Methionine] inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein]; Chloroquine inhibits the reaction [[Diethylnitrosamine co-treated with N-nitrosomorpholine] results in increased expression of and results in increased phosphorylation of AKT1 protein]; Hesperidin inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein]; neferine inhibits the reaction [Diethylnitrosamine results in increased expression of AKT1 mRNA] Diethylnitrosamine results in increased expression of AKT1; Diethylnitrosamine results in increased expression of AKT1 mRNA
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CTD RGD |
PMID:17055752 PMID:20583210 PMID:24990399 PMID:27151938 PMID:30423403 PMID:30779474 PMID:38367245 PMID:25999787 More...
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RGD:152177911 |
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
|
|
| G
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Akt2
|
AKT serine/threonine kinase 2
|
increases phosphorylation
|
ISO
|
N-nitrosodiethylamine increases phosphorylation of Akt2 protein in liver
|
RGD |
PMID:28100771 |
RGD:127285675 |
NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420
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|
| G
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Alad
|
aminolevulinate dehydratase
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ALAD mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041
|
|
| G
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Alas2
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5'-aminolevulinate synthase 2
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALAS2 mRNA Diethylnitrosamine results in decreased expression of ALAS2 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043
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| G
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Alb
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albumin
|
decreases expression multiple interactions increases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ALB mRNA; Diethylnitrosamine results in decreased expression of ALB protein [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of ALB protein; piperlongumine inhibits the reaction [[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of ALB protein]; Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of ALB protein] Diethylnitrosamine results in increased expression of ALB mRNA; Diethylnitrosamine results in increased expression of ALB protein
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CTD |
PMID:20360939 PMID:28804948 PMID:29698782 PMID:35113675 PMID:38369053 |
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NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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| G
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Alcam
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activated leukocyte cell adhesion molecule
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of ALCAM mRNA
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CTD |
PMID:24535843 |
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NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876
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| G
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Aldh18a1
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aldehyde dehydrogenase 18 family, member A1
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multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ALDH18A1 mRNA Diethylnitrosamine results in increased expression of ALDH18A1 mRNA
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CTD |
PMID:17602206 PMID:24535843 |
|
NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383
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| G
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Aldh1a1
|
aldehyde dehydrogenase 1 family, member A1
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of ALDH1A1 mRNA Diethylnitrosamine results in increased expression of ALDH1A1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH1A1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ALDH1A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of ALDH1A1 mRNA
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CTD |
PMID:17602206 PMID:18977376 PMID:21295105 PMID:21527772 PMID:21813463 PMID:22129741 PMID:22687989 PMID:23830814 PMID:28943392 More...
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|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500
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| G
|
Aldh1a2
|
aldehyde dehydrogenase 1 family, member A2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ALDH1A2 mRNA
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CTD |
PMID:20360939 |
|
NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
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|
| G
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Aldh1a3
|
aldehyde dehydrogenase 1 family, member A3
|
multiple interactions
|
EXP
|
[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of ALDH1A3 mRNA
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CTD |
PMID:18977376 |
|
NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777
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|
| G
|
Aldh1a7
|
aldehyde dehydrogenase family 1, subfamily A7
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ALDH1A7 mRNA
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CTD |
PMID:22129741 |
|
NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523
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|
| G
|
Aldh1b1
|
aldehyde dehydrogenase 1 family, member B1
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ALDH1B1 mRNA Diethylnitrosamine results in increased expression of ALDH1B1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365
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| G
|
Aldh3a1
|
aldehyde dehydrogenase 3 family, member A1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ALDH3A1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3A1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ALDH3A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ALDH3A1 mRNA
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CTD |
PMID:18164116 PMID:19638242 PMID:22129741 PMID:28943392 |
|
NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151
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|
| G
|
Aldh3a2
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aldehyde dehydrogenase 3 family, member A2
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multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ALDH3A2 mRNA
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CTD |
PMID:24535843 |
|
NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648
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|
| G
|
Aldh3b1
|
aldehyde dehydrogenase 3 family, member B1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3B1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538
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|
| G
|
Aldoa
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aldolase, fructose-bisphosphate A
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ALDOA mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ALDOA mRNA Diethylnitrosamine results in increased expression of ALDOA mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211
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|
| G
|
Aldob
|
aldolase, fructose-bisphosphate B
|
multiple interactions
|
ISO
|
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of ALDOB protein
|
CTD |
PMID:23457121 |
|
NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740
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|
| G
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Alox5
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arachidonate 5-lipoxygenase
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ALOX5 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
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|
| G
|
Alpg
|
alkaline phosphatase, germ cell
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ALPG mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 9:95,187,995...95,205,127
Ensembl chr 9:95,198,334...95,205,742
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|
| G
|
Alpl
|
alkaline phosphatase, biomineralization associated
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALPL mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ALPL mRNA; Allyl Compounds inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Sulfides inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of ALPL protein]; Tocotrienols affects the reaction [[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein]
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CTD |
PMID:15548946 PMID:15554553 PMID:17602206 PMID:18164116 |
|
NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
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|
| G
|
Alpp
|
alkaline phosphatase, placental
|
multiple interactions increases activity
|
EXP
|
Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased activity of ALPP protein]
|
CTD |
PMID:15563447 |
|
NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451
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|
| G
|
Amacr
|
alpha-methylacyl-CoA racemase
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of AMACR mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AMACR mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379
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|
| G
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Amot
|
angiomotin
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increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of AMOT mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:113,778,990...113,837,846
Ensembl chr X:113,781,526...113,837,482
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|
| G
|
Ampd3
|
adenosine monophosphate deaminase 3
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AMPD3 mRNA Diethylnitrosamine results in increased expression of AMPD3 mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608
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|
| G
|
Amy1
|
amylase alpha 1
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AMY1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AMY1 mRNA Diethylnitrosamine results in decreased expression of AMY1 mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr 2:204,071,101...204,085,910
Ensembl chr 2:204,071,098...204,086,239
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|
| G
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Anapc5
|
anaphase-promoting complex subunit 5
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANAPC5 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762
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|
| G
|
Ang
|
angiogenin
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANG mRNA Diethylnitrosamine results in decreased expression of ANG mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:24535843 |
|
NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106
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|
| G
|
Angpt1
|
angiopoietin 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ANGPT1 mRNA Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of ANGPT1 mRNA]
|
CTD |
PMID:17034775 |
|
NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
|
|
| G
|
Angpt2
|
angiopoietin 2
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ANGPT2 mRNA Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of ANGPT2 mRNA]
|
CTD |
PMID:17034775 |
|
NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239
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|
| G
|
Angptl2
|
angiopoietin-like 2
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANGPTL2 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 3:36,914,876...36,944,715
Ensembl chr 3:36,914,745...36,945,876
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|
| G
|
Angptl4
|
angiopoietin-like 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANGPTL4 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANGPTL4 mRNA
|
CTD |
PMID:17602206 PMID:22129741 |
|
NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681
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|
| G
|
Angptl8
|
angiopoietin-like 8
|
decreases expression increases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ANGPTL8 mRNA Diethylnitrosamine results in increased expression of ANGPTL8 mRNA
|
CTD |
PMID:21527772 PMID:24535843 |
|
NCBI chr 8:28,652,555...28,654,581
Ensembl chr 8:28,652,555...28,654,581
|
|
| G
|
Ankrd17
|
ankyrin repeat domain 17
|
multiple interactions increases expression
|
EXP
|
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr14:18,007,342...18,145,980
Ensembl chr14:18,008,859...18,145,980
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|
| G
|
Ankrd29
|
ankyrin repeat domain 29
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANKRD29 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr18:3,711,052...3,768,997
Ensembl chr18:3,711,059...3,769,098
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|
| G
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Anln
|
anillin, actin binding protein
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of ANLN mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ANLN mRNA]
|
CTD |
PMID:17854601 PMID:19041683 |
|
NCBI chr 8:29,134,222...29,197,513
Ensembl chr 8:29,134,222...29,197,513
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|
| G
|
Anp32a
|
acidic nuclear phosphoprotein 32 family member A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANP32A mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922
|
|
| G
|
Anp32b
|
acidic nuclear phosphoprotein 32 family member B
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ANP32B mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437
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|
| G
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Anxa1
|
annexin A1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA1 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA1 mRNA Diethylnitrosamine results in increased expression of ANXA1 mRNA; Diethylnitrosamine results in increased expression of ANXA1 protein
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CTD |
PMID:18164116 PMID:19638242 PMID:20935162 PMID:28943392 |
|
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831
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|
| G
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Anxa2
|
annexin A2
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of ANXA2 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA2 mRNA
|
CTD |
PMID:12771043 PMID:19638242 PMID:21813463 PMID:24535843 PMID:28943392 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631
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|
| G
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Anxa3
|
annexin A3
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of ANXA3 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA3 mRNA
|
CTD |
PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849
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|
| G
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Anxa5
|
annexin A5
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multiple interactions increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA Diethylnitrosamine results in increased expression of ANXA5 mRNA; Diethylnitrosamine results in increased expression of ANXA5 protein [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA5 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ANXA5 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA5 mRNA
|
CTD |
PMID:17917374 PMID:18164116 PMID:19638242 PMID:20935162 PMID:28943392 |
|
NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400
|
|
| G
|
Anxa7
|
annexin A7
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ANXA7 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ANXA7 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891
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|
| G
|
Anxa8
|
annexin A8
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA8 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr16:9,403,267...9,418,317
Ensembl chr16:9,403,353...9,418,310
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|
| G
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Aoc1
|
amine oxidase, copper containing 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of AOC1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704
|
|
| G
|
Aox1
|
aldehyde oxidase 1
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of AOX1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AOX1 mRNA
|
CTD |
PMID:14656948 PMID:16158176 |
|
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
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|
| G
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Ap1m1
|
adaptor related protein complex 1 subunit mu 1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of AP1M1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr16:17,620,910...17,636,431
Ensembl chr16:17,616,187...17,636,462
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|
| G
|
Ap2b1
|
adaptor related protein complex 2 subunit beta 1
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of AP2B1 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AP2B1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539
|
|
| G
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Apaf1
|
apoptotic peptidase activating factor 1
|
multiple interactions affects expression
|
ISO EXP
|
AHR protein affects the reaction [Diethylnitrosamine affects the expression of APAF1 mRNA]; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of APAF1 mRNA] [3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of APAF1 mRNA
|
CTD |
PMID:19996281 PMID:27048571 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
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|
| G
|
Apc
|
APC regulator of WNT signaling pathway
|
decreases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of APC mRNA epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in decreased expression of APC mRNA]; epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in decreased expression of APC protein]; theaflavin inhibits the reaction [Diethylnitrosamine results in decreased expression of APC mRNA]; theaflavin inhibits the reaction [Diethylnitrosamine results in decreased expression of APC protein] Diethylnitrosamine results in decreased expression of APC mRNA; Diethylnitrosamine results in decreased expression of APC protein
|
CTD |
PMID:20360939 PMID:27058323 |
|
NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022
|
|
| G
|
Apcs
|
amyloid P component, serum
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APCS mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824
|
|
| G
|
Apeg3
|
antisense paternally expressed gene 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of APEG3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:76,154,484...76,155,415
Ensembl chr 1:76,154,982...76,155,263
|
|
| G
|
Apex1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APEX1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA Diethylnitrosamine results in decreased expression of APEX1 mRNA
|
CTD |
PMID:11323195 PMID:17602206 PMID:18253720 PMID:18775883 |
|
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329
|
|
| G
|
Aph1b
|
aph-1 homolog B, gamma secretase subunit
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of APH1B mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APH1B mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of APH1B mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:22129741 PMID:24535843 |
|
NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:76,310,380...76,331,428
|
|
| G
|
Apln
|
apelin
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of APLN mRNA Diethylnitrosamine results in increased expression of APLN mRNA
|
CTD |
PMID:18164116 PMID:19041683 |
|
NCBI chr X:132,058,739...132,091,518
Ensembl chr X:132,081,759...132,091,246
|
|
| G
|
Aplnr
|
apelin receptor
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of APLNR mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of APLNR mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:90,624,055...90,627,700
Ensembl chr 3:90,624,012...90,627,908
|
|
| G
|
Apoa1
|
apolipoprotein A1
|
multiple interactions
|
EXP
|
[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of APOA1 protein
|
CTD |
PMID:20935162 |
|
NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729
|
|
| G
|
Apoa2
|
apolipoprotein A2
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of APOA2 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APOA2 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410
|
|
| G
|
Apoa4
|
apolipoprotein A4
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOA4 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APOA4 mRNA Diethylnitrosamine results in increased expression of APOA4 mRNA
|
CTD |
PMID:18164116 PMID:24535843 PMID:28943392 |
|
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
|
|
| G
|
Apoc2
|
apolipoprotein C2
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of APOC2 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APOC2 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438
|
|
| G
|
Apoc3
|
apolipoprotein C3
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of APOC3 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679
|
|
| G
|
Apoe
|
apolipoprotein E
|
multiple interactions
|
EXP
|
[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of APOE protein
|
CTD |
PMID:20935162 |
|
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
|
|
| G
|
Apof
|
apolipoprotein F
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APOF mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 7:1,285,222...1,286,659
Ensembl chr 7:1,285,222...1,286,659
|
|
| G
|
Apol2
|
apolipoprotein L2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APOL3 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:111,211,893...111,217,223
|
|
| G
|
Apol9a
|
apolipoprotein L9a
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of APOL9A mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 7:111,021,452...111,030,380
Ensembl chr 7:111,021,453...111,028,213
|
|
| G
|
Apom
|
apolipoprotein M
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOM mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APOM mRNA Diethylnitrosamine results in increased expression of APOM mRNA Diethylnitrosamine results in decreased expression of APOM mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218
|
|
| G
|
Apon
|
apolipoprotein N
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of APON mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 7:1,271,514...1,272,917
Ensembl chr 7:1,271,515...1,272,917
|
|
| G
|
App
|
amyloid beta precursor protein
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of APP mRNA; Diethylnitrosamine results in increased expression of APP protein [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APP mRNA
|
CTD |
PMID:17602206 PMID:19542621 PMID:19638242 PMID:20387270 PMID:24535843 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
|
|
| G
|
Aprt
|
adenine phosphoribosyl transferase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of APRT mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr19:67,534,737...67,537,027
|
|
| G
|
Aqp1
|
aquaporin 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of AQP1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504
|
|
| G
|
Aqp4
|
aquaporin 4
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of AQP4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098
|
|
| G
|
Aqp7
|
aquaporin 7
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of AQP7 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AQP7 mRNA
|
CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618
|
|
| G
|
Aqp9
|
aquaporin 9
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of AQP9 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
|
|
| G
|
Arap1
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ARAP1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 1:165,160,701...165,226,219
Ensembl chr 1:165,160,678...165,226,218
|
|
| G
|
Arfip1
|
ARF interacting protein 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ARFIP1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 2:172,141,862...172,224,464
Ensembl chr 2:172,141,859...172,221,280
|
|
| G
|
Arg1
|
arginase 1
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ARG1 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARG1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713
|
|
| G
|
Arg2
|
arginase 2
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ARG2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375
|
|
| G
|
Arhgap19
|
Rho GTPase activating protein 19
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ARHGAP19 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP19 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 1:250,519,703...250,566,705
Ensembl chr 1:250,530,214...250,580,190
|
|
| G
|
Arhgap22
|
Rho GTPase activating protein 22
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ARHGAP22 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr16:8,480,222...8,637,823
Ensembl chr16:8,479,956...8,637,822
|
|
| G
|
Arhgap24
|
Rho GTPase activating protein 24
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ARHGAP24 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950
|
|
| G
|
Arhgap29
|
Rho GTPase activating protein 29
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ARHGAP29 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 2:212,744,626...212,816,710
Ensembl chr 2:212,755,803...212,986,729
|
|
| G
|
Arhgap5
|
Rho GTPase activating protein 5
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ARHGAP5 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP5 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 6:75,711,199...75,774,636
Ensembl chr 6:75,711,515...75,774,636
|
|
| G
|
Arhgef19
|
Rho guanine nucleotide exchange factor 19
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ARHGEF19 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGEF19 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 5:158,818,840...158,837,196
Ensembl chr 5:158,818,932...158,837,196
|
|
| G
|
Arhgef2
|
Rho/Rac guanine nucleotide exchange factor 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARHGEF2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646
|
|
| G
|
Arhgef37
|
Rho guanine nucleotide exchange factor 37
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ARHGEF37 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr18:57,205,621...57,271,284
Ensembl chr18:57,230,117...57,271,031
|
|
| G
|
Arl13a
|
ARF like GTPase 13A
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARL13A mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr X:101,673,637...101,699,986
Ensembl chr X:101,673,652...101,699,984
|
|
| G
|
Arl3
|
ARF like GTPase 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ARL3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:255,342,078...255,388,087
Ensembl chr 1:255,342,076...255,388,279
|
|
| G
|
Arl5a
|
ARF like GTPase 5A
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ARL5A mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARL5A mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 3:57,287,599...57,312,488
Ensembl chr 3:57,289,846...57,312,488
|
|
| G
|
Armcx1
|
armadillo repeat containing, X-linked 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ARMCX1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr X:102,192,225...102,196,130
Ensembl chr X:102,192,015...102,199,115
|
|
| G
|
Armcx3
|
armadillo repeat containing, X-linked 3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ARMCX3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:102,230,464...102,234,017
Ensembl chr X:102,219,848...102,263,297
|
|
| G
|
Arnt
|
aryl hydrocarbon receptor nuclear translocator
|
multiple interactions
|
ISO
|
[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of ARNT mRNA; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of ARNT mRNA]
|
CTD |
PMID:19182440 |
|
NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546
|
|
| G
|
Arpc1b
|
actin related protein 2/3 complex, subunit 1B
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ARPC1B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504
|
|
| G
|
Arrb1
|
arrestin, beta 1
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of ARRB1 mRNA [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ARRB1 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB1 mRNA]
|
CTD |
PMID:17942915 PMID:20360939 |
|
NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859
|
|
| G
|
Arrb2
|
arrestin, beta 2
|
multiple interactions increases expression
|
EXP
|
chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 mRNA]; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB2 protein] Diethylnitrosamine results in increased expression of ARRB2 mRNA; Diethylnitrosamine results in increased expression of ARRB2 protein
|
CTD |
PMID:21167192 PMID:22393308 |
|
NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487
|
|
| G
|
Arrdc2
|
arrestin domain containing 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARRDC2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr16:18,635,883...18,640,019
Ensembl chr16:18,635,883...18,640,158
|
|
| G
|
Arrdc3
|
arrestin domain containing 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARRDC3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875
|
|
| G
|
Arsb
|
arylsulfatase B
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ARSB gene
|
CTD |
PMID:23968726 |
|
NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:26,736,957...26,897,611
|
|
| G
|
Art1
|
ADP-ribosyltransferase 1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of ART1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 1:165,890,032...165,899,154
Ensembl chr 1:165,890,086...165,899,146
|
|
| G
|
As3mt
|
arsenite methyltransferase
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of AS3MT mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249
|
|
| G
|
Asah1
|
N-acylsphingosine amidohydrolase 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ASAH1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305
|
|
| G
|
Asb10
|
ankyrin repeat and SOCS box-containing 10
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ASB10 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 4:11,522,531...11,531,946
Ensembl chr 4:11,522,887...11,531,505
|
|
| G
|
Asb14
|
ankyrin repeat and SOCS box-containing 14
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ASB14 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASB14 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr16:2,102,303...2,131,379
Ensembl chr16:2,102,363...2,130,590
|
|
| G
|
Asb5
|
ankyrin repeat and SOCS box-containing 5
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ASB5 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr16:43,970,940...44,038,318
Ensembl chr16:43,970,940...44,010,437
|
|
| G
|
Asf1b
|
anti-silencing function 1B histone chaperone
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ASF1B mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASF1B mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr19:41,085,786...41,100,352
Ensembl chr19:41,086,114...41,100,352
|
|
| G
|
Asic5
|
acid sensing ion channel subunit family member 5
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ASIC5 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:169,606,059...169,634,885
Ensembl chr 2:169,606,059...169,634,885
|
|
| G
|
Asip
|
agouti signaling protein
|
increases response to substance
|
ISO
|
A protein results in increased susceptibility to Diethylnitrosamine
|
CTD |
PMID:15175105 |
|
NCBI chr 3:163,933,768...164,021,377
Ensembl chr 3:164,015,903...164,021,378
|
|
| G
|
Asns
|
asparagine synthetase (glutamine-hydrolyzing)
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of ASNS mRNA [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASNS mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASNS mRNA]
|
CTD |
PMID:17942915 PMID:19638242 PMID:22129741 |
|
NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
|
|
| G
|
Aspg
|
asparaginase
|
multiple interactions
|
ISO EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ASPG mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ASPG mRNA
|
CTD |
PMID:24535843 PMID:28943392 |
|
NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417
|
|
| G
|
Aspm
|
assembly factor for spindle microtubules
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ASPM mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489
|
|
| G
|
Asrgl1
|
asparaginase and isoaspartyl peptidase 1
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ASRGL1 mRNA Diethylnitrosamine results in decreased expression of ASRGL1 mRNA
|
CTD |
PMID:17602206 PMID:19638242 |
|
NCBI chr 1:215,436,180...215,456,188
Ensembl chr 1:215,435,218...215,456,198
|
|
| G
|
Ass1
|
argininosuccinate synthase 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ASS1 protein [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ASS1 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of ASS1 protein
|
CTD |
PMID:20935162 PMID:28943392 |
|
NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627
|
|
| G
|
Astl
|
astacin like metalloendopeptidase
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASTL mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 3:135,016,444...135,032,177
Ensembl chr 3:135,016,444...135,032,177
|
|
| G
|
Atad1
|
ATPase family, AAA domain containing 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ATAD1 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 1:239,957,329...240,023,792
Ensembl chr 1:239,957,882...240,009,822
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| G
|
Atf2
|
activating transcription factor 2
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ATF2 mRNA
|
CTD |
PMID:19690152 |
|
NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745
|
|
| G
|
Atf3
|
activating transcription factor 3
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of ATF3 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA
|
CTD |
PMID:18978307 PMID:19690152 |
|
NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
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| G
|
Atf4
|
activating transcription factor 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATF4 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
|
|
| G
|
Atf5
|
activating transcription factor 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATF5 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183
|
|
| G
|
Atic
|
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATIC mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756
|
|
| G
|
Atl2
|
atlastin GTPase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATL2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320
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| G
|
Atm
|
ATM serine/threonine kinase
|
multiple interactions decreases expression decreases activity increases phosphorylation increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA; ATM protein inhibits the reaction [Diethylnitrosamine results in increased cleavage of and results in increased activity of CASP3 protein]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATR mRNA]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATR protein]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDKN2A protein]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 mRNA]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 protein]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRP53 protein]; ATM protein promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; ATM protein promotes the reaction [Diethylnitrosamine results in increased expression of TERT protein]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATM mRNA]; XRCC6 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of ATM protein] Diethylnitrosamine results in decreased expression of ATM protein Diethylnitrosamine results in decreased activity of ATM protein ATM protein affects the reaction [Diethylnitrosamine results in increased expression of TP53 protein]
|
CTD |
PMID:11751435 PMID:17854601 PMID:17917374 PMID:18506893 PMID:19919837 |
|
NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
|
|
| G
|
Atox1
|
antioxidant 1 copper chaperone
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ATOX1 mRNA caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ATOX1 mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585
|
|
| G
|
Atp11c
|
ATPase phospholipid transporting 11C
|
multiple interactions increases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP11C mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432
|
|
| G
|
Atp13a1
|
ATPase 13A1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP13A1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr16:19,649,065...19,665,126
Ensembl chr16:19,649,066...19,665,120
|
|
| G
|
Atp13a4
|
ATPase 13A4
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of ATP13A4 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP13A4 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr11:84,727,014...84,864,747
Ensembl chr11:84,731,041...84,864,747
|
|
| G
|
Atp1a1
|
ATPase Na+/K+ transporting subunit alpha 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP1A1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425
|
|
| G
|
Atp1a4
|
ATPase Na+/K+ transporting subunit alpha 4
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ATP1A4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr13:87,216,139...87,252,155
Ensembl chr13:87,216,139...87,251,724
|
|
| G
|
Atp1b1
|
ATPase Na+/K+ transporting subunit beta 1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP1B1 mRNA Diethylnitrosamine results in increased expression of ATP1B1 mRNA
|
CTD |
PMID:17602206 PMID:19638242 |
|
NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549
|
|
| G
|
Atp1b3
|
ATPase Na+/K+ transporting subunit beta 3
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ATP1B3 mRNA
|
CTD |
PMID:11323195 |
|
NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304 Ensembl chr 8:65,253,361...65,254,304
|
|
| G
|
Atp2a1
|
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
|
multiple interactions decreases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP2A1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:190,457,198...190,475,423
|
|
| G
|
Atp2b2
|
ATPase plasma membrane Ca2+ transporting 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP2B2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239
|
|
| G
|
Atp2c1
|
ATPase secretory pathway Ca2+ transporting 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP2C1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 8:114,913,551...115,034,706
Ensembl chr 8:114,913,415...115,038,826
|
|
| G
|
Atp5f1b
|
ATP synthase F1 subunit beta
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein; [Diethylnitrosamine co-treated with Methapyrilene] results in decreased expression of ATP5F1B protein; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ATP5F1B protein
|
CTD |
PMID:28903497 |
|
NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462
|
|
| G
|
Atp5if1
|
ATP synthase inhibitory factor subunit 1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ATP5IF1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of ATP5IF1 promoter; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ATP5IF1 mRNA Diethylnitrosamine results in increased expression of ATP5IF1 mRNA
|
CTD |
PMID:19638242 PMID:25374375 PMID:28943392 |
|
NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677
|
|
| G
|
Atp5po
|
ATP synthase peripheral stalk subunit OSCP
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP5PO mRNA Diethylnitrosamine results in decreased expression of ATP5PO mRNA
|
CTD |
PMID:17602206 PMID:20360939 |
|
NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520
|
|
| G
|
Atp6v0d2
|
ATPase H+ transporting V0 subunit D2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ATP6V0D2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245
|
|
| G
|
Atp6v0e2
|
ATPase, H+ transporting V0 subunit e2
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ATP6V0E2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680
|
|
| G
|
Atp6v1c2
|
ATPase H+ transporting V1 subunit C2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP6V1C2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747
|
|
| G
|
Atp6v1d
|
ATPase H+ transporting V1 subunit D
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATP6V1D mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346
|
|
| G
|
Atp7b
|
ATPase copper transporting beta
|
affects response to substance
|
EXP
|
ATP7B protein affects the susceptibility to Diethylnitrosamine
|
CTD |
PMID:11509115 |
|
NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801
|
|
| G
|
Atp8b2
|
ATPase phospholipid transporting 8B2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ATP8B2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 2:177,676,205...177,699,575
Ensembl chr 2:177,676,208...177,699,575
|
|
| G
|
Atp8b3
|
ATPase phospholipid transporting 8B3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ATP8B3 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 7:9,823,496...9,846,137
Ensembl chr 7:9,826,275...9,846,195
|
|
| G
|
Atp8b4
|
ATPase phospholipid transporting 8B4 (putative)
|
multiple interactions decreases expression increases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP8B4 mRNA] Diethylnitrosamine results in decreased expression of ATP8B4 mRNA
|
CTD |
PMID:17942915 PMID:24535843 |
|
NCBI chr 3:134,008,367...134,212,394
Ensembl chr 3:134,009,580...134,210,260
|
|
| G
|
Atr
|
ATR serine/threonine kinase
|
multiple interactions increases expression
|
ISO
|
ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATR mRNA]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATR protein] Diethylnitrosamine results in increased expression of ATR mRNA; Diethylnitrosamine results in increased expression of ATR protein
|
CTD |
PMID:19919837 |
|
NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
|
|
| G
|
Atrn
|
attractin
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ATRN mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360
|
|
| G
|
Atrnl1
|
attractin like 1
|
multiple interactions decreases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ATRNL1 mRNA Diethylnitrosamine results in decreased expression of ATRNL1 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ATRNL1 mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 1:266,676,051...267,216,847
Ensembl chr 1:266,675,852...267,216,842
|
|
| G
|
Atxn10
|
ataxin 10
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ATXN10 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATXN10 mRNA
|
CTD |
PMID:17602206 PMID:18164116 |
|
NCBI chr 7:118,321,516...118,444,967
Ensembl chr 7:118,319,490...118,445,636
|
|
| G
|
Aurka
|
aurora kinase A
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AURKA mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AURKA mRNA]; XRCC6 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AURKA mRNA]
|
CTD |
PMID:17854601 PMID:18506893 PMID:24535843 |
|
NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771
|
|
| G
|
Aurkb
|
aurora kinase B
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AURKB mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285
|
|
| G
|
Avil
|
advillin
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AVIL mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436
|
|
| G
|
Avpr1a
|
arginine vasopressin receptor 1A
|
decreases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of AVPR1A mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AVPR1A mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AVPR1A mRNA
|
CTD |
PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837
|
|
| G
|
Axin2
|
axin 2
|
multiple interactions
|
ISO
|
[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of AXIN2 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of AXIN2 mRNA
|
CTD |
PMID:33398415 |
|
NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575
|
|
| G
|
Axl
|
Axl receptor tyrosine kinase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of AXL mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009
|
|
| G
|
Azgp1
|
alpha-2-glycoprotein 1, zinc-binding
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of AZGP1 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of AZGP1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of AZGP1 promoter; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AZGP1 mRNA
|
CTD |
PMID:19041683 PMID:19638242 PMID:25374375 PMID:28943392 |
|
NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020
|
|
| G
|
B2m
|
beta-2 microglobulin
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of B2M mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B2M mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
|
|
| G
|
B3galnt1
|
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of B3GALNT1 mRNA Diethylnitrosamine results in increased expression of B3GALNT1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404
|
|
| G
|
B3galt5
|
Beta-1,3-galactosyltransferase 5
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GALT5 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr11:49,053,959...49,100,398
Ensembl chr11:49,006,560...49,101,283
|
|
| G
|
B3gat1
|
beta-1,3-glucuronyltransferase 1
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of B3GAT1 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B3GAT1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 8:33,362,791...33,390,446
Ensembl chr 8:33,363,048...33,390,443
|
|
| G
|
B3gnt9
|
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GNT9 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of B3GNT9 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr19:50,039,649...50,042,206
Ensembl chr19:50,030,866...50,043,339
|
|
| G
|
B4galnt1
|
beta-1,4-N-acetyl-galactosaminyl transferase 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of B4GALNT1 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 7:64,873,909...64,881,512
Ensembl chr 7:64,874,022...64,881,516
|
|
| G
|
B4galt6
|
beta-1,4-galactosyltransferase 6
|
increases expression
|
EXP ISO
|
Diethylnitrosamine results in increased expression of B4GALT6 mRNA
|
CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr18:12,233,350...12,290,204
Ensembl chr18:12,233,351...12,290,204
|
|
| G
|
Baat
|
bile acid CoA:amino acid N-acyltransferase
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of BAAT mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BAAT mRNA
|
CTD |
PMID:12771043 PMID:19638242 PMID:28943392 |
|
NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181
|
|
| G
|
Bad
|
BCL2-associated agonist of cell death
|
multiple interactions decreases expression
|
EXP
|
[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of BAD mRNA; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAD protein] Diethylnitrosamine results in decreased expression of BAD mRNA; Diethylnitrosamine results in decreased expression of BAD protein
|
CTD |
PMID:27048571 PMID:31129132 |
|
NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
|
|
| G
|
Bag3
|
BAG cochaperone 3
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of BAG3 mRNA IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of BAG3 mRNA]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of BAG3 mRNA]
|
CTD |
PMID:18691550 |
|
NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280
|
|
| G
|
Bag4
|
BAG cochaperone 4
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BAG4 gene
|
CTD |
PMID:23968726 |
|
NCBI chr16:72,991,407...73,008,620
Ensembl chr16:72,991,362...73,013,273
|
|
| G
|
Bahd1
|
bromo adjacent homology domain containing 1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BAHD1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 3:126,341,853...126,368,281
Ensembl chr 3:126,345,371...126,368,278
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| G
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Bak1
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BCL2-antagonist/killer 1
|
multiple interactions
|
EXP
|
3,4,5,4'-tetramethoxystilbene inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BAK1 mRNA]; [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BAK1 mRNA
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CTD |
PMID:27048571 |
|
NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974
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| G
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Banf1
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barrier to autointegration nuclear assembly factor 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BANF1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552
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|
| G
|
Barx2
|
BARX homeobox 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BARX2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 8:38,509,277...38,576,978
Ensembl chr 8:38,509,277...38,576,978
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|
| G
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Basp1
|
brain abundant, membrane attached signal protein 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of BASP1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BASP1 mRNA
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CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 2:77,546,628...77,594,297
Ensembl chr 2:77,546,092...77,597,178
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| G
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Bax
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BCL2 associated X, apoptosis regulator
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multiple interactions decreases expression increases expression
|
EXP ISO
|
[2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BAX protein; [5,7-dimethoxyflavone co-treated with Diethylnitrosamine] results in increased expression of BAX protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein; [Diethylnitrosamine co-treated with Cyclohexanols] results in decreased expression of BAX protein; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of BAX mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BAX mRNA; chrysin promotes the reaction [Diethylnitrosamine results in increased expression of BAX protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BAX protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Resveratrol promotes the reaction [Diethylnitrosamine results in increased expression of BAX protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; zerumbone promotes the reaction [[2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BAX protein]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein] Diethylnitrosamine results in increased expression of BAX mRNA; Diethylnitrosamine results in increased expression of BAX protein Diethylnitrosamine results in decreased expression of BAX mRNA; Diethylnitrosamine results in decreased expression of BAX protein CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA]; maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased expression of BAX protein]
|
CTD |
PMID:11915028 PMID:17393424 PMID:18056438 PMID:19073162 PMID:19100860 PMID:19931519 PMID:20452335 PMID:21167192 PMID:21554863 PMID:21607683 PMID:22393308 PMID:23830814 PMID:26464624 PMID:27553677 PMID:30423403 PMID:31129132 PMID:34726822 PMID:35437842 More...
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|
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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| G
|
Bbc3
|
Bcl-2 binding component 3
|
increases expression
|
ISO
|
N-nitrosodiethylamine increases expression of Bbc3 mRNA in liver
|
RGD |
PMID:28100771 |
RGD:127285675 |
NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666
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|
| G
|
Bbox1
|
gamma-butyrobetaine hydroxylase 1
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of BBOX1 mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064
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|
| G
|
Bbs7
|
Bardet-Biedl syndrome 7
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of BBS7 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 2:121,362,884...121,402,473
Ensembl chr 2:121,362,885...121,402,473
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|
| G
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Bcas1
|
brain enriched myelin associated protein 1
|
multiple interactions increases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCAS1 mRNA Diethylnitrosamine results in increased expression of BCAS1 mRNA
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CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 3:179,554,754...179,637,800
Ensembl chr 3:179,551,704...179,637,743
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|
| G
|
Bcat2
|
branched chain amino acid transaminase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BCAT2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:105,175,157...105,196,474
Ensembl chr 1:105,176,977...105,196,463
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|
| G
|
Bckdhb
|
branched chain keto acid dehydrogenase E1 subunit beta
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of BCKDHB mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BCKDHB mRNA]
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CTD |
PMID:17942915 |
|
NCBI chr 8:93,725,277...93,907,799
Ensembl chr 8:93,725,275...93,907,798
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|
| G
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Bckdk
|
branched chain ketoacid dehydrogenase kinase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BCKDK mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453
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|
| G
|
Bcl10
|
BCL10, immune signaling adaptor
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BCL10 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829
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|
| G
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Bcl2
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BCL2, apoptosis regulator
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multiple interactions increases expression decreases response to substance
|
ISO EXP
|
BCL2 protein inhibits the reaction [TGFA protein results in increased susceptibility to Diethylnitrosamine]; maculosin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein] N-nitrosodiethylamine increases expression of Bcl2 mRNA in liver Diethylnitrosamine results in increased expression of BCL2 mRNA; Diethylnitrosamine results in increased expression of BCL2 protein [2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BCL2 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BCL2 mRNA; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of BCL2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BCL2 mRNA; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2 protein]; morin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; neferine inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; neferine inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of BCL2 mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; Resveratrol inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein]; Silymarin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of BCL2 mRNA]; Thioctic Acid inhibits the reaction [[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BCL2 mRNA]; thymoquinone inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of BCL2 mRNA]; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; zerumbone inhibits the reaction [[2-aminofluorene co-treated with Diethylnitrosamine] results in increased expression of BCL2 protein]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 protein] BCL2 protein results in decreased susceptibility to Diethylnitrosamine
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CTD RGD |
PMID:11915028 PMID:12000706 PMID:15682466 PMID:19073162 PMID:19931519 PMID:20452335 PMID:21295105 PMID:21776270 PMID:22393308 PMID:23830814 PMID:24535843 PMID:29923357 PMID:30423403 PMID:31129132 PMID:34726822 PMID:35437842 PMID:28100771 More...
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RGD:127285675 |
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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|
| G
|
Bcl2l1
|
Bcl2-like 1
|
multiple interactions increases expression
|
EXP ISO
|
5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein; [Diethylnitrosamine co-treated with Colchicine] results in decreased expression of BCL2L1 protein; [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BCL2L1 protein; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of BCL2L1 mRNA; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; chrysin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]; IFNA2 protein affects the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of BCL2L1 protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2L1 protein] N-nitrosodiethylamine increases expression of Bcl2l1 mRNA in liver Diethylnitrosamine results in increased expression of BCL2L1 mRNA; Diethylnitrosamine results in increased expression of BCL2L1 protein
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CTD RGD |
PMID:11749691 PMID:11915028 PMID:21167192 PMID:21554863 PMID:21607683 PMID:22393308 PMID:23830814 PMID:31129132 PMID:28100771 More...
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RGD:127285675 |
NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907 Ensembl chr 1:161,745,540...161,764,907
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|
| G
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Bcl2l11
|
Bcl2-like 11
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increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BCL2L11 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695
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|
| G
|
Bcl2l14
|
Bcl2-like 14
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increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BCL2L14 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079
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|
| G
|
Bcl2l2
|
Bcl2-like 2
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379
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|
| G
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Bcl6
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BCL6, transcription repressor
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multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCL6 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047
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|
| G
|
Bco1
|
beta-carotene oxygenase 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BCO1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917
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|
| G
|
Bco2
|
beta-carotene oxygenase 2
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of BCO2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:59,778,571...59,803,597
Ensembl chr 8:59,778,575...59,799,168
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|
| G
|
Bcor
|
BCL6 co-repressor
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BCOR gene
|
CTD |
PMID:23968726 |
|
NCBI chr X:13,282,431...13,402,254
Ensembl chr X:13,360,376...13,402,254
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|
| G
|
Bcr
|
BCR activator of RhoGEF and GTPase
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA
|
CTD |
PMID:18253720 |
|
NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333
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|
| G
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Bcs1l
|
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BCS1L mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 9:83,614,045...83,618,052
Ensembl chr 9:83,613,975...83,618,257
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|
| G
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Bdh1
|
3-hydroxybutyrate dehydrogenase 1
|
decreases expression multiple interactions
|
EXP
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Diethylnitrosamine results in decreased expression of BDH1 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BDH1 mRNA
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CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636
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|
| G
|
Bdh2
|
3-hydroxybutyrate dehydrogenase 2
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BDH2 mRNA Diethylnitrosamine results in decreased expression of BDH2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BDH2 mRNA
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CTD |
PMID:17602206 PMID:24535843 |
|
NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006
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|
| G
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Becn1
|
beclin 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BECN1 protein; alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BECN1 protein]; alogliptin promotes the reaction [taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BECN1 protein]]; taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BECN1 protein]; taxifolin promotes the reaction [alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BECN1 protein]]
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CTD |
PMID:33840231 |
|
NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002
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|
| G
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Bend5
|
BEN domain containing 5
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of BEND5 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 5:131,519,214...131,565,228
Ensembl chr 5:131,519,214...131,762,906
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|
| G
|
Bex1
|
brain expressed X-linked 1
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increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BEX2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:104,010,639...104,012,143
Ensembl chr X:104,010,371...104,011,236
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|
| G
|
Bex2
|
brain expressed X-linked 2
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increases expression multiple interactions
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ISO EXP
|
Diethylnitrosamine results in increased expression of BEX1 mRNA Diethylnitrosamine promotes the reaction [Carbon Tetrachloride results in increased expression of BEX1 mRNA] [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BEX1 mRNA
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CTD |
PMID:19638242 PMID:23288052 PMID:24535843 PMID:28943392 |
|
NCBI chr X:103,811,458...103,812,986
Ensembl chr X:103,808,935...103,812,092
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|
| G
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Bex3
|
brain expressed X-linked 3
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX3 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of BEX3 mRNA Diethylnitrosamine results in increased expression of BEX3 mRNA
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CTD |
PMID:18164116 PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906
|
|
| G
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Bex4
|
brain expressed, X-linked 4
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of BEX4 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX4 mRNA
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CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr X:103,923,609...103,925,041
Ensembl chr X:103,923,338...103,925,496
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|
| G
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Bgn
|
biglycan
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of BGN mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799
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|
| G
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Bhlhe41
|
basic helix-loop-helix family, member e41
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BHLHE41 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355
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|
| G
|
Bhmt
|
betaine-homocysteine S-methyltransferase
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BHMT mRNA [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of BHMT mRNA
|
CTD |
PMID:28943392 PMID:29127188 |
|
NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715
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|
| G
|
Bhmt2
|
betaine-homocysteine S-methyltransferase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of BHMT2 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326
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|
| G
|
Bicc1
|
BicC family RNA binding protein 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BICC1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr20:17,448,745...17,685,887
Ensembl chr20:17,448,765...17,685,885
|
|
| G
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Bid
|
BH3 interacting domain death agonist
|
affects response to substance
|
ISO
|
BID protein affects the susceptibility to Diethylnitrosamine
|
CTD |
PMID:15904428 |
|
NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275
|
|
| G
|
Bik
|
BCL2-interacting killer
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BIK mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317
|
|
| G
|
Birc3
|
baculoviral IAP repeat-containing 3
|
multiple interactions
|
EXP
|
[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BIRC3 mRNA
|
CTD |
PMID:27048571 |
|
NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590
|
|
| G
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Birc5
|
baculoviral IAP repeat-containing 5
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of BIRC5 mRNA Diethylnitrosamine affects the localization of and results in increased expression of BIRC5 protein Diethylnitrosamine results in increased expression of BIRC5 mRNA; Diethylnitrosamine results in increased expression of BIRC5 protein [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BIRC5 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BIRC5 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BIRC5 mRNA]
|
CTD |
PMID:17854601 PMID:18164116 PMID:20514400 PMID:21776270 PMID:24535843 PMID:33398415 More...
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|
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
|
|
| G
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Blnk
|
B-cell linker
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BLNK mRNA Diethylnitrosamine results in increased expression of BLNK mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533
|
|
| G
|
Bloc1s2
|
biogenesis of lysosomal organelles complex-1, subunit 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BLOC1S2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:252,973,818...252,980,873
Ensembl chr 1:252,973,202...252,980,873
|
|
| G
|
Bltp1
|
bridge-like lipid transfer protein family member 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BLTP1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:121,636,181...121,852,802
Ensembl chr 2:121,636,323...121,852,802
|
|
| G
|
Blvrb
|
biliverdin reductase B
|
multiple interactions
|
ISO
|
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of BLVRB protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BLVRB mRNA
|
CTD |
PMID:23457121 PMID:24535843 |
|
NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
|
|
| G
|
Bmal1
|
basic helix-loop-helix ARNT like 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of BMAL1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMAL1 mRNA
|
CTD |
PMID:18164116 PMID:22129741 |
|
NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739
|
|
| G
|
Bmal2
|
basic helix-loop-helix ARNT like 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BMAL2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:181,429,097...181,478,384
Ensembl chr 4:181,430,159...181,478,382
|
|
| G
|
Bmf
|
Bcl2 modifying factor
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of BMF mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258
|
|
| G
|
Bmp1
|
bone morphogenetic protein 1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP1 mRNA Diethylnitrosamine results in increased expression of BMP1 mRNA
|
CTD |
PMID:17602206 PMID:20360939 |
|
NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485
|
|
| G
|
Bmp2
|
bone morphogenetic protein 2
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BMP2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BMP2 mRNA
|
CTD |
PMID:17602206 PMID:24535843 |
|
NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760
|
|
| G
|
Bmp2k
|
BMP-2 inducible kinase
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of BMP2K mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,785,169...12,882,657
|
|
| G
|
Bmp5
|
bone morphogenetic protein 5
|
multiple interactions decreases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMP5 mRNA Diethylnitrosamine results in decreased expression of BMP5 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of BMP5 mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189
|
|
| G
|
Bmp7
|
bone morphogenetic protein 7
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of BMP7 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137
|
|
| G
|
Bok
|
BCL2 family apoptosis regulator BOK
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BOK mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833
|
|
| G
|
Bphl
|
biphenyl hydrolase like
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BPHL mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr17:31,006,283...31,042,631
Ensembl chr17:31,004,972...31,042,632
|
|
| G
|
Bpifb4
|
BPI fold containing family B, member 4
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of BPIFB4 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 3:162,881,478...162,908,207
Ensembl chr 3:162,881,437...162,908,207
|
|
| G
|
Braf
|
B-Raf proto-oncogene, serine/threonine kinase
|
increases mutagenesis
|
ISO
|
Diethylnitrosamine results in increased mutagenesis of BRAF gene
|
CTD |
PMID:15592514 PMID:25319454 |
|
NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931
|
|
| G
|
Brca1
|
BRCA1, DNA repair associated
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of BRCA1 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BRCA1 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
|
|
| G
|
Brca2
|
BRCA2, DNA repair associated
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of BRCA2 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BRCA2 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194
|
|
| G
|
Brf1
|
BRF1 general transcription factor IIIB subunit
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of BRF1 protein
|
CTD |
PMID:37021545 |
|
NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386
|
|
| G
|
Bri3
|
brain protein I3
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of BRI3 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr12:15,454,673...15,478,319
Ensembl chr12:15,454,673...15,478,319
|
|
| G
|
Brinp3
|
BMP/retinoic acid inducible neural specific 3
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of BRINP3 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr13:60,964,127...61,397,044
Ensembl chr13:60,966,100...61,397,039
|
|
| G
|
Bspry
|
B-box and SPRY domain containing
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BSPRY mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:80,942,979...80,988,154
|
|
| G
|
Bst2
|
bone marrow stromal cell antigen 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of BST2 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BST2 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
|
|
| G
|
Btaf1
|
B-TFIID TATA-box binding protein associated factor 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of BTAF1 mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr 1:244,065,728...244,156,457
Ensembl chr 1:244,065,743...244,156,457
|
|
| G
|
Btf3
|
basic transcription factor 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of BTF3 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125 Ensembl chr13:31,394,011...31,401,125
|
|
| G
|
Btf3l4
|
basic transcription factor 3-like 4
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of BTF3L4 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:128,796,594...128,816,219
Ensembl chr 5:128,796,594...128,816,602
|
|
| G
|
Btg2
|
BTG anti-proliferation factor 2
|
decreases response to substance increases expression decreases expression multiple interactions
|
ISO EXP
|
BTG2 protein results in decreased susceptibility to Diethylnitrosamine Diethylnitrosamine results in increased expression of BTG2 mRNA Diethylnitrosamine results in decreased expression of BTG2 mRNA Diethylnitrosamine affects the localization of and results in increased expression of BTG2 protein
|
CTD |
PMID:18393292 PMID:19100860 PMID:19254457 PMID:19638242 PMID:21607683 PMID:21813463 PMID:24535843 More...
|
|
NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690
|
|
| G
|
Btg3
|
BTG anti-proliferation factor 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BTG3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082
|
|
| G
|
Btn1a1
|
butyrophilin, subfamily 1, member A1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of BTN1A1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr17:42,080,217...42,092,286
Ensembl chr17:42,081,527...42,092,276
|
|
| G
|
Bub1
|
BUB1 mitotic checkpoint serine/threonine kinase
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BUB1 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of BUB1 mRNA]
|
CTD |
PMID:17854601 PMID:24535843 |
|
NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921
|
|
| G
|
C1galt1
|
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of C1GALT1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 4:36,894,440...36,932,434
Ensembl chr 4:36,894,488...36,932,441
|
|
| G
|
C1qa
|
complement C1q A chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of C1QA mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732
|
|
| G
|
C1qb
|
complement C1q B chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of C1QB mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840
|
|
| G
|
C1qc
|
complement C1q C chain
|
multiple interactions increases expression
|
ISO EXP
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of C1QC mRNA]
|
CTD |
PMID:17942915 PMID:19638242 |
|
NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468
|
|
| G
|
C1qtnf3
|
C1q and TNF related 3
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of C1QTNF3 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559
|
|
| G
|
C1s
|
complement C1s
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of C1S mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736
|
|
| G
|
C4b
|
complement C4B
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of C4B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289
|
|
| G
|
C4bpb
|
complement component 4 binding protein, beta
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of C4BPB mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793
|
|
| G
|
C5
|
complement C5
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of C5 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468
|
|
| G
|
C6
|
complement C6
|
decreases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of C6 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of C6 mRNA
|
CTD |
PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120
|
|
| G
|
C7h19orf25
|
similar to human chromosome 19 open reading frame 25
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of C7H19ORF25 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:10,040,929...10,043,057
Ensembl chr 7:10,040,893...10,043,042
|
|
| G
|
C8b
|
complement C8 beta chain
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of C8B mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of C8B mRNA
|
CTD |
PMID:24535843 PMID:28943392 |
|
NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516
|
|
| G
|
C8g
|
complement C8 gamma chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of C8G mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 3:28,718,648...28,720,232
|
|
| G
|
C9
|
complement C9
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of C9 mRNA
|
CTD |
PMID:12771043 |
|
NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752
|
|
| G
|
Ca1
|
carbonic anhydrase 1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CAR1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454
|
|
| G
|
Ca11
|
carbonic anhydrase 11
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAR11 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:105,306,347...105,311,651
Ensembl chr 1:105,302,289...105,311,832
|
|
| G
|
Ca14
|
carbonic anhydrase 14
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CAR14 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863
|
|
| G
|
Ca3
|
carbonic anhydrase 3
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CA3 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CA3 mRNA; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAR3 mRNA] Diethylnitrosamine results in decreased expression of CA3 mRNA; Diethylnitrosamine results in decreased expression of CAR3 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524
|
|
| G
|
Ca4
|
carbonic anhydrase 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAR4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916
|
|
| G
|
Ca5a
|
carbonic anhydrase 5A
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of CA5A mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CA5A mRNA Diethylnitrosamine results in decreased expression of CAR5A mRNA
|
CTD |
PMID:19638242 PMID:21527772 PMID:24535843 PMID:28943392 |
|
NCBI chr19:66,881,678...66,911,486
Ensembl chr19:66,881,693...66,911,486
|
|
| G
|
Cab39l
|
calcium binding protein 39-like
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CAB39L mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr15:37,782,778...37,885,191
Ensembl chr15:37,782,870...37,919,742
|
|
| G
|
Cables1
|
Cdk5 and Abl enzyme substrate 1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CABLES1 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956
|
|
| G
|
Cacna1a
|
calcium voltage-gated channel subunit alpha1 A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1A mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599
|
|
| G
|
Cacna1b
|
calcium voltage-gated channel subunit alpha1 B
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CACNA1B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:27,779,166...27,944,285
|
|
| G
|
Cacna1c
|
calcium voltage-gated channel subunit alpha1 C
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CACNA1C mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762
|
|
| G
|
Cacna1g
|
calcium voltage-gated channel subunit alpha1 G
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CACNA1G mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634
|
|
| G
|
Cacna1h
|
calcium voltage-gated channel subunit alpha1 H
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CACNA1H mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771
|
|
| G
|
Cacna2d1
|
calcium voltage-gated channel auxiliary subunit alpha2delta 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CACNA2D1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147
|
|
| G
|
Cacnb1
|
calcium voltage-gated channel auxiliary subunit beta 1
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CACNB1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:83,494,509...83,515,164
Ensembl chr10:83,494,509...83,515,146
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| G
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Cacng5
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calcium voltage-gated channel auxiliary subunit gamma 5
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CACNG5 mRNA
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CTD |
PMID:18164116 |
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NCBI chr10:93,327,142...93,369,244
Ensembl chr10:93,327,150...93,336,667
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| G
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Cad
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carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CAD mRNA
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CTD |
PMID:17602206 |
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NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:31,012,091...31,035,297
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| G
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Cadm1
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cell adhesion molecule 1
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multiple interactions decreases expression increases methylation
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EXP
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[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of CADM1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CADM1 gene Diethylnitrosamine results in decreased expression of CADM1 mRNA; Diethylnitrosamine results in decreased expression of CADM1 protein Diethylnitrosamine results in increased methylation of CADM1 5' UTR
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CTD |
PMID:17428255 PMID:21163286 |
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NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192
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| G
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Cadps
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calcium dependent secretion activator
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CADPS mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of CADPS promoter
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CTD |
PMID:25374375 |
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NCBI chr15:14,719,078...15,173,218
Ensembl chr15:14,720,726...15,173,211
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| G
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Cadps2
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calcium dependent secretion activator 2
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multiple interactions
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CADPS2 mRNA
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CTD |
PMID:24535843 |
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NCBI chr 4:52,746,054...53,275,252
Ensembl chr 4:52,746,065...53,275,004
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| G
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Calcb
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calcitonin-related polypeptide, beta
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of CALCB mRNA
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CTD |
PMID:21527772 |
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NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654
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| G
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Cald1
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caldesmon 1
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multiple interactions increases expression
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EXP
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Dahuang Zhechong pill inhibits the reaction [Diethylnitrosamine results in increased expression of CALD1 protein]; Sorafenib inhibits the reaction [Diethylnitrosamine results in increased expression of CALD1 protein]
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CTD |
PMID:36731809 |
|
NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085
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| G
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Calm2
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calmodulin 2
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CALM2 mRNA
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CTD |
PMID:17602206 |
|
NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657 Ensembl chr 6:64,519,554...64,520,657
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| G
|
Calml4
|
calmodulin-like 4
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multiple interactions increases expression
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CALML4 mRNA Diethylnitrosamine results in increased expression of CALML4 mRNA
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CTD |
PMID:24535843 |
|
NCBI chr 8:72,218,870...72,230,650
Ensembl chr 8:72,218,613...72,230,650
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| G
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Calr
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calreticulin
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CALR mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CALR mRNA
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CTD |
PMID:17602206 PMID:18544905 |
|
NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236
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|
| G
|
Camk2a
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calcium/calmodulin-dependent protein kinase II alpha
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multiple interactions
|
ISO
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[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CAMK2A gene
|
CTD |
PMID:23968726 |
|
NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504
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|
| G
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Camk2d
|
calcium/calmodulin-dependent protein kinase II delta
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CAMK2D mRNA
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CTD |
PMID:20360939 |
|
NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276
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|
| G
|
Camkv
|
CaM kinase-like vesicle-associated
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increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CAMKV mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 8:117,505,439...117,519,785
Ensembl chr 8:117,505,408...117,519,797
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| G
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Capg
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capping actin protein, gelsolin like
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multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CAPG gene
|
CTD |
PMID:23968726 |
|
NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672
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|
| G
|
Capn10
|
calpain 10
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CAPN10 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 9:100,943,665...100,957,910
Ensembl chr 9:100,945,551...100,957,912
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|
| G
|
Capn8
|
calpain 8
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multiple interactions decreases expression
|
EXP
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caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CAPN8 mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820
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|
| G
|
Capn9
|
calpain 9
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decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CAPN9 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr19:69,446,847...69,483,810
Ensembl chr19:69,446,847...69,483,810
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|
| G
|
Capza2
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capping actin protein of muscle Z-line subunit alpha 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CAPZA2 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CAPZA2 mRNA]
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CTD |
PMID:17942915 |
|
NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938
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|
| G
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Car2
|
carbonic anhydrase 2
|
increases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in increased expression of CA2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CAR2 mRNA [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAR2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CA2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CA2 mRNA
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CTD |
PMID:14656948 PMID:16158176 PMID:18164116 PMID:19638242 PMID:24535843 PMID:28943392 More...
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|
NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064
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|
| G
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Card10
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caspase recruitment domain family, member 10
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multiple interactions increases expression
|
ISO
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IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of CARD10 mRNA]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CARD10 mRNA]
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CTD |
PMID:18691550 |
|
NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:112,210,776...112,239,806
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|
| G
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Cars1
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cysteinyl-tRNA synthetase 1
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multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CARS1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407
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| G
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Cask
|
calcium/calmodulin dependent serine protein kinase
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increases expression
|
EXP
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Diethylnitrosamine results in increased expression of CASK mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948
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|
| G
|
Caskin1
|
CASK interacting protein 1
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multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CASKIN1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr10:14,016,780...14,037,927
Ensembl chr10:14,018,012...14,037,924
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|
| G
|
Casp1
|
caspase 1
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multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
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|
| G
|
Casp12
|
caspase 12
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multiple interactions increases expression
|
EXP ISO
|
[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of CASP12 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CASP12 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CASP12 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP12 mRNA Diethylnitrosamine results in increased expression of CASP12 mRNA
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CTD |
PMID:17602206 PMID:23830814 PMID:24535843 PMID:27048571 |
|
NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442
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|
| G
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Casp3
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caspase 3
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multiple interactions decreases expression increases cleavage increases expression decreases activity increases activity
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ISO EXP
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ATM protein inhibits the reaction [Diethylnitrosamine results in increased cleavage of and results in increased activity of CASP3 protein]; Cholic Acid inhibits the reaction [Diethylnitrosamine results in increased cleavage of CASP3 protein]; CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP3 protein]; CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 mRNA]; Diethylnitrosamine results in increased cleavage of and results in increased activity of CASP3 protein; eumelanin inhibits the reaction [Diethylnitrosamine results in increased expression of CASP3 protein]; maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; maculosin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein] Diethylnitrosamine results in decreased expression of CASP3 mRNA; Diethylnitrosamine results in decreased expression of CASP3 protein Diethylnitrosamine results in increased expression of CASP3 mRNA; Diethylnitrosamine results in increased expression of CASP3 protein 5,7-dimethoxyflavone promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 protein]; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP3 protein; [Diethylnitrosamine co-treated with chrysin] results in increased expression of CASP3 protein; [Diethylnitrosamine co-treated with lanreotide] results in increased activity of CASP3 protein; [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP3 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA; [Sodium Fluoride results in increased abundance of Fluorides] promotes the reaction [Diethylnitrosamine results in increased activity of CASP3 protein]; alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP3 protein]; alogliptin promotes the reaction [taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP3 protein]]; Diethylnitrosamine promotes the reaction [[Sodium Fluoride results in increased abundance of Fluorides] which results in increased activity of CASP3 protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; formylchromone analog inhibits the reaction [Diethylnitrosamine results in decreased activity of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP3 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP3 mRNA]; Hesperidin promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 protein]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; Plant Oils inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein modified form]; Polyphenols inhibits the reaction [Diethylnitrosamine results in increased activity of CASP3 protein]; taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP3 protein]; taxifolin promotes the reaction [alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP3 protein]]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP3 protein] Diethylnitrosamine results in decreased expression of CASP3 mRNA; Diethylnitrosamine results in decreased expression of CASP3 protein; Diethylnitrosamine results in decreased expression of CASP3 protein modified form
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CTD |
PMID:18056438 PMID:19427195 PMID:19602430 PMID:19874807 PMID:19919837 PMID:19931519 PMID:21167192 PMID:21167249 PMID:21554863 PMID:21907755 PMID:22393308 PMID:24954034 PMID:26464624 PMID:27151938 PMID:30423403 PMID:30779474 PMID:30920066 PMID:31129132 PMID:33840231 PMID:34726822 PMID:35437842 PMID:36113623 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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| G
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Casp4
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caspase 4
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multiple interactions increases expression
|
EXP ISO
|
3,4,5,4'-tetramethoxystilbene affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP4 mRNA]; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CASP4 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CASP4 mRNA; [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA] Diethylnitrosamine results in increased expression of CASP4 mRNA
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CTD |
PMID:17602206 PMID:18544905 PMID:24535843 PMID:27048571 |
|
NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727
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|
| G
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Casp7
|
caspase 7
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multiple interactions increases activity
|
ISO
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CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP7 protein]
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CTD |
PMID:21167249 |
|
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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|
| G
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Casp8
|
caspase 8
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multiple interactions decreases activity
|
EXP ISO
|
[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of CASP8 mRNA; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of CASP8 mRNA; [Diethylnitrosamine co-treated with thiosalicylic acid] results in increased activity of CASP8 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP8 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA] S-allylcysteine inhibits the reaction [Diethylnitrosamine results in decreased activity of CASP8 protein]
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CTD |
PMID:18544905 PMID:19427195 PMID:21907755 PMID:23830814 PMID:27048571 PMID:31067004 More...
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|
NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
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|
| G
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Casp8ap2
|
caspase 8 associated protein 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CASP8AP2 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CASP8AP2 mRNA]
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CTD |
PMID:17854601 |
|
NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
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|
| G
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Casp9
|
caspase 9
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increases expression multiple interactions decreases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CASP9 mRNA [3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of CASP9 mRNA; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP9 protein; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of CASP9 mRNA; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein; [ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA; alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP9 protein]; alogliptin promotes the reaction [taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP9 protein]]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased cleavage of and results in decreased expression of CASP9 protein]; geraniol inhibits the reaction [[ferric nitrilotriacetate co-treated with Diethylnitrosamine] results in decreased expression of CASP9 mRNA]; morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; neferine inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein]; taxifolin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP9 protein]; taxifolin promotes the reaction [alogliptin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CASP9 protein]]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 mRNA]; zolmitriptan inhibits the reaction [Diethylnitrosamine results in decreased expression of CASP9 protein] Diethylnitrosamine results in decreased expression of CASP9 mRNA; Diethylnitrosamine results in decreased expression of CASP9 protein MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CASP9 mRNA]
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CTD |
PMID:18691550 PMID:19931519 PMID:21907755 PMID:23830814 PMID:27048571 PMID:30423403 PMID:31129132 PMID:33840231 More...
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|
Ensembl chr 5:159,391,188...159,409,648
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|
| G
|
Cat
|
catalase
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decreases expression decreases abundance affects activity decreases activity multiple interactions
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ISO EXP
|
Diethylnitrosamine results in decreased expression of CAT mRNA Diethylnitrosamine results in decreased abundance of CAT protein Diethylnitrosamine affects the activity of CAT protein Diethylnitrosamine results in decreased activity of CAT protein Diethylnitrosamine results in decreased expression of CAT mRNA; Diethylnitrosamine results in decreased expression of CAT protein [3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of CAT mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased activity of CAT protein; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased activity of CAT protein; [Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid co-treated with isoquercitrin analog] results in increased expression of CAT mRNA; [Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of CAT protein; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CAT mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of CAT protein; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CAT mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of CAT protein; [Sodium Fluoride results in increased abundance of Fluorides] promotes the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; brucine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; citral inhibits the reaction [Diethylnitrosamine results in decreased expression of CAT protein]; Hesperidin inhibits the reaction [[Diethylnitrosamine co-treated with ferric nitrilotriacetate] results in decreased activity of CAT protein]; Hesperidin inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; neferine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Plant Oils inhibits the reaction [Diethylnitrosamine affects the activity of CAT protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Silymarin inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CAT mRNA]; Vitamin E inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein] [Gold binds to NKCT1 protein, Naja kaouthia] inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; eumelanin inhibits the reaction [Diethylnitrosamine results in decreased abundance of CAT protein]; Fluorouracil inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; indoleacetic acid inhibits the reaction [Diethylnitrosamine results in decreased expression of CAT mRNA]; maculosin inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]
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CTD |
PMID:11323195 PMID:16144695 PMID:16188247 PMID:17761372 PMID:18253720 PMID:18544905 PMID:19107877 PMID:19115120 PMID:19294768 PMID:19602430 PMID:20935162 PMID:20972371 PMID:22393308 PMID:24060683 PMID:24144777 PMID:27048571 PMID:27836789 PMID:28804948 PMID:28943392 PMID:29923357 PMID:30098279 PMID:30298849 PMID:30423403 PMID:30779474 PMID:30920066 PMID:32302048 PMID:34726822 PMID:35437842 PMID:36113623 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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| G
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Catsperd
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cation channel sperm associated auxiliary subunit delta
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of CATSPERD mRNA
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CTD |
PMID:24535843 |
|
NCBI chr 9:1,546,903...1,585,470
Ensembl chr 9:1,548,205...1,585,467
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| G
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Cav1
|
caveolin 1
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CAV1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAV mRNA
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CTD |
PMID:18164116 PMID:21527772 PMID:24535843 |
|
NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740
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|
| G
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Cav2
|
caveolin 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CAV2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425
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| G
|
Cavin2
|
caveolae associated protein 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CAVIN2 mRNA
|
CTD |
PMID:21527772 PMID:24535843 |
|
NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024
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|
| G
|
Cavin3
|
caveolae associated protein 3
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CAVIN3 mRNA Diethylnitrosamine results in increased expression of CAVIN3 mRNA
|
CTD |
PMID:14656948 PMID:19638242 |
|
NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981
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|
| G
|
Cbarp
|
CACN subunit beta associated regulatory protein
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CBARP gene
|
CTD |
PMID:23968726 |
|
NCBI chr 7:10,217,314...10,225,855
Ensembl chr 7:10,217,328...10,225,854
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|
| G
|
Cblc
|
Cbl proto-oncogene C
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CBLC mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709
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| G
|
Cbr1
|
carbonyl reductase 1
|
increases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CBR1 mRNA
|
CTD |
PMID:12771043 PMID:19638242 PMID:21607683 |
|
NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104 Ensembl chr11:46,378,411...46,381,104
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| G
|
Cbs
|
cystathionine beta synthase
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CBS mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CBS mRNA Diethylnitrosamine results in decreased expression of CBS mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066
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|
| G
|
Cbx3
|
chromobox 3
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CBX3 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911
|
|
| G
|
Cbx5
|
chromobox 5
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CBX5 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118
|
|
| G
|
Cbx6
|
chromobox 6
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CBX6 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:113,253,364...113,263,413
Ensembl chr 7:113,253,364...113,263,413
|
|
| G
|
Ccar1
|
cell division cycle and apoptosis regulator 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CCAR1 mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr20:31,228,624...31,271,233
Ensembl chr20:31,228,624...31,271,227
|
|
| G
|
Ccdc120
|
coiled-coil domain containing 120
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CCDC120 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCDC120 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:17,437,219...17,443,716
Ensembl chr X:17,425,624...17,444,717
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|
| G
|
Ccdc121
|
coiled-coil domain containing 121
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCDC121 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 6:30,690,831...30,693,437
Ensembl chr 6:30,690,831...30,693,437
|
|
| G
|
Ccdc136
|
coiled-coil domain containing 136
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CCDC136 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 4:58,963,196...58,992,962
Ensembl chr 4:58,962,908...58,992,975
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|
| G
|
Ccdc149
|
coiled-coil domain containing 149
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CCDC149 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:62,722,567...62,817,778
Ensembl chr14:62,722,600...62,817,777
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|
| G
|
Ccdc158
|
coiled-coil domain containing 158
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCDC158 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr14:15,695,456...15,752,896
Ensembl chr14:15,695,512...15,752,941
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|
| G
|
Ccdc162
|
coiled-coil domain containing 162
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CCDC162 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr20:46,627,277...46,820,216
Ensembl chr20:46,627,277...46,818,249
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|
| G
|
Ccdc33
|
coiled-coil domain containing 33
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CCDC33 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 8:67,331,519...67,430,194
Ensembl chr 8:67,331,519...67,413,485
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|
| G
|
Ccdc68
|
coiled-coil domain containing 68
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CCDC68 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526
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|
| G
|
Ccdc80
|
coiled-coil domain containing 80
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCDC80 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844
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|
| G
|
Cckbr
|
cholecystokinin B receptor
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCKBR mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745
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|
| G
|
Ccl11
|
C-C motif chemokine ligand 11
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCL11 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
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|
| G
|
Ccl2
|
C-C motif chemokine ligand 2
|
multiple interactions increases expression
|
EXP
|
[Copper co-treated with Diethylnitrosamine] results in increased expression of CCL2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA; [Iron co-treated with Diethylnitrosamine] results in increased expression of CCL2 mRNA; Iron promotes the reaction [[Copper co-treated with Diethylnitrosamine] results in increased expression of CCL2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA] Diethylnitrosamine results in increased expression of CCL2 mRNA; Diethylnitrosamine results in increased expression of CCL2 protein
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CTD |
PMID:20302851 PMID:21295105 PMID:25051504 |
|
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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|
| G
|
Ccl21
|
C-C motif chemokine ligand 21
|
multiple interactions increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA Diethylnitrosamine results in increased expression of CCL21B mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL21B mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CCL21B mRNA
|
CTD |
PMID:17917374 PMID:18164116 PMID:19638242 PMID:28943392 |
|
NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540
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|
| G
|
Ccl28
|
C-C motif chemokine ligand 28
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CCL28 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:53,334,071...53,358,709
|
|
| G
|
Ccl3
|
C-C motif chemokine ligand 3
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA; CCL3 protein affects the reaction [Diethylnitrosamine results in increased expression of MMP9 mRNA]; CCL3 protein affects the reaction [Diethylnitrosamine results in increased expression of MMP9 protein]
|
CTD |
PMID:16284949 PMID:17917374 |
|
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
|
|
| G
|
Ccl5
|
C-C motif chemokine ligand 5
|
multiple interactions increases expression decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CCL5 mRNA Diethylnitrosamine results in increased expression of CCL5 protein Diethylnitrosamine results in decreased expression of CCL5 protein
|
CTD |
PMID:20360939 PMID:25051504 |
|
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
|
|
| G
|
Ccl9
|
C-C motif chemokine ligand 9
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CCL6 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCL6 mRNA
|
CTD |
PMID:17602206 PMID:18164116 |
|
NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877
|
|
| G
|
Ccn1
|
cellular communication network factor 1
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN1 mRNA [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of CCN1 mRNA
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CTD |
PMID:18164116 PMID:33398415 |
|
NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
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|
| G
|
Ccn2
|
cellular communication network factor 2
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA [1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Diethylnitrosamine] results in increased expression of CCN2 mRNA Diethylnitrosamine results in increased expression of CCN2 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:21391223 |
|
NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976
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|
| G
|
Ccn3
|
cellular communication network factor 3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CCN3 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 7:87,983,788...87,990,810
Ensembl chr 7:87,982,216...87,994,581
|
|
| G
|
Ccn4
|
cellular communication network factor 4
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCN4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:100,534,578...100,566,287
Ensembl chr 7:100,534,505...100,563,094
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|
| G
|
Ccn5
|
cellular communication network factor 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN5 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
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|
| G
|
Ccna2
|
cyclin A2
|
multiple interactions increases expression
|
ISO EXP
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 mRNA]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNA2 protein] Diethylnitrosamine results in increased expression of CCNA2 mRNA; Diethylnitrosamine results in increased expression of CCNA2 protein [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNA2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNA2 mRNA
|
CTD |
PMID:17854601 PMID:18164116 PMID:19638242 PMID:22129741 PMID:24535843 |
|
NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
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|
| G
|
Ccnb1
|
cyclin B1
|
multiple interactions increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCNB1 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB1 mRNA] [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 protein; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 protein; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CCNB1 mRNA
|
CTD |
PMID:12616621 PMID:17854601 PMID:18164116 PMID:19996281 PMID:22129741 PMID:24535843 PMID:25242409 PMID:37021545 More...
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|
NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
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|
| G
|
Ccnb2
|
cyclin B2
|
multiple interactions increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCNB2 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB2 mRNA]
|
CTD |
PMID:17854601 PMID:24535843 PMID:25242409 |
|
NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682
|
|
| G
|
Ccnc
|
cyclin C
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:40,063,623...40,093,370
|
|
| G
|
Ccnd1
|
cyclin D1
|
multiple interactions increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with Cholic Acid] results in increased expression of CCND1 protein; [Diethylnitrosamine co-treated with Dietary Fats] affects the expression of CCND1 mRNA; [Diethylnitrosamine co-treated with Dietary Fats] affects the expression of CCND1 protein; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CCND1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA; ATM protein promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; Fosinopril inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; Losartan inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; Perindopril inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; Sorafenib inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; XRCC6 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 protein] N-nitrosodiethylamine increases expression of CcnD1 protein in rat liver N-nitrosodiethylamine increases expression of Ccnd1 protein in liver Diethylnitrosamine results in increased expression of CCND1 mRNA; Diethylnitrosamine results in increased expression of CCND1 protein Diethylnitrosamine results in increased expression of CCND1; Diethylnitrosamine results in increased expression of CCND1 mRNA; Diethylnitrosamine results in increased expression of CCND1 protein 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; [Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCND1 protein; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCND1 protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CCND1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of CCND1 promoter; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCND1 mRNA]; lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]; malachite green promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; Orphenadrine promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]; Phenobarbital promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]
|
CTD RGD |
PMID:10906429 PMID:11831363 PMID:12175673 PMID:12616621 PMID:14633663 PMID:17055752 PMID:17917374 PMID:18253720 PMID:18506893 PMID:18544905 PMID:18691550 PMID:18978307 PMID:19254457 PMID:19551842 PMID:19638242 PMID:19690152 PMID:19822196 PMID:19919837 PMID:20101389 PMID:20583210 PMID:21554863 PMID:23665939 PMID:24012840 PMID:24535843 PMID:25374375 PMID:26589970 PMID:27058323 PMID:27151938 PMID:29859236 PMID:30826251 PMID:37021545 PMID:11797828 PMID:28100771 More...
|
RGD:151356973, RGD:127285675 |
NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
|
|
| G
|
Ccndbp1
|
cyclin D1 binding protein 1
|
decreases response to substance
|
ISO
|
CCNDBP1 protein results in decreased susceptibility to Diethylnitrosamine
|
CTD |
PMID:16501603 |
|
NCBI chr 3:128,416,105...128,427,985
Ensembl chr 3:128,416,054...128,436,008
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|
| G
|
Ccne1
|
cyclin E1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CCNE1 mRNA]; malachite green promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein]; metanil yellow promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein]; Phenobarbital promotes the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of CCNE1 protein] N-nitrosodiethylamine increases expression of CcnE protein in rat liver N-nitrosodiethylamine increases expression of Ccne1 mRNA in liver [Diethylnitrosamine co-treated with Dietary Fats] affects the expression of CCNE1 protein Diethylnitrosamine results in increased expression of CCNE1 mRNA Diethylnitrosamine results in increased expression of CCNE1 mRNA; Diethylnitrosamine results in increased expression of CCNE1 protein
|
CTD RGD |
PMID:10906429 PMID:11831363 PMID:14633663 PMID:19254457 PMID:24012840 PMID:24535843 PMID:30826251 PMID:37021545 PMID:11797828 PMID:28100771 More...
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RGD:151356973, RGD:127285675 |
NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
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|
| G
|
Ccne2
|
cyclin E2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCNE2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
|
|
| G
|
Ccnf
|
cyclin F
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CCNF mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNF mRNA]
|
CTD |
PMID:17854601 |
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NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,758,421...13,783,837
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| G
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Ccng1
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cyclin G1
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multiple interactions increases expression affects response to substance
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ISO EXP
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[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA Diethylnitrosamine results in increased expression of CCNG1 mRNA CCNG1 protein affects the susceptibility to Diethylnitrosamine [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA
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CTD |
PMID:12668979 PMID:17602206 PMID:17917374 PMID:18544905 PMID:19100860 PMID:19638242 PMID:21607683 More...
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NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
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| G
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Ccnh
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cyclin H
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increases expression multiple interactions
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ISO EXP
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Diethylnitrosamine results in increased expression of CCNH mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCNH mRNA MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNH mRNA]
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CTD |
PMID:17602206 PMID:18691550 |
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NCBI chr 2:17,570,449...17,591,078
Ensembl chr 2:17,570,263...17,614,860
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| G
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Ccr1
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C-C motif chemokine receptor 1
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multiple interactions
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ISO
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CCR1 protein affects the reaction [Diethylnitrosamine results in increased expression of MMP9 mRNA]; CCR1 protein affects the reaction [Diethylnitrosamine results in increased expression of MMP9 protein]
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CTD |
PMID:16284949 |
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NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374
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| G
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Ccr4
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C-C motif chemokine receptor 4
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CCR4 mRNA
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CTD |
PMID:20360939 |
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NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642
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| G
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Ccs
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copper chaperone for superoxide dismutase
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCS mRNA
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CTD |
PMID:17602206 |
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NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260
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| G
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Cct2
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chaperonin containing TCP1 subunit 2
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCT2 mRNA
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CTD |
PMID:17602206 |
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NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977
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| G
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Cct3
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chaperonin containing TCP1 subunit 3
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCT3 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CCT3 mRNA
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CTD |
PMID:17602206 PMID:18164116 |
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NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925
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| G
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Cd14
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CD14 molecule
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multiple interactions increases expression
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EXP ISO
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD14 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CD14 mRNA Diethylnitrosamine results in increased expression of CD14 mRNA
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CTD |
PMID:17602206 PMID:20360939 PMID:24535843 |
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NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
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| G
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Cd151
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CD151 molecule (Raph blood group)
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD151 mRNA
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CTD |
PMID:20360939 |
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NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784
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| G
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Cd163
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CD163 molecule
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decreases expression multiple interactions
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ISO
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Diethylnitrosamine results in decreased expression of CD163 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CD163 mRNA
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CTD |
PMID:24535843 |
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NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146
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| G
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Cd24
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CD24 molecule
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multiple interactions increases expression
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD24 mRNA Diethylnitrosamine results in increased expression of CD24 mRNA
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CTD |
PMID:18164116 PMID:19638242 |
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NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
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| G
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Cd276
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Cd276 molecule
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multiple interactions increases expression
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EXP ISO
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD276 mRNA Diethylnitrosamine results in increased expression of CD276 mRNA
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CTD |
PMID:18164116 PMID:19638242 PMID:24535843 |
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NCBI chr 8:67,833,587...67,863,918
Ensembl chr 8:67,829,048...67,864,505
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| G
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Cd2ap
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CD2-associated protein
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of CD2AP mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CD2AP mRNA
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CTD |
PMID:24535843 |
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NCBI chr 9:25,580,071...25,679,968
Ensembl chr 9:25,583,975...25,679,968
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| G
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Cd36
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CD36 molecule
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increases expression
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EXP ISO
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Diethylnitrosamine results in increased expression of CD36 mRNA
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CTD |
PMID:12771043 PMID:19638242 |
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NCBI chr 4:18,209,088...18,302,142
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| G
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Cd37
|
CD37 molecule
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multiple interactions
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ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CD37 gene
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CTD |
PMID:23968726 |
|
NCBI chr 1:104,855,622...104,861,111
Ensembl chr 1:104,849,166...104,861,276
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| G
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Cd38
|
CD38 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD38 mRNA
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CTD |
PMID:18164116 |
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NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505
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| G
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Cd4
|
Cd4 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CD4 mRNA
|
CTD |
PMID:23830814 |
|
NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461
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| G
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Cd40
|
CD40 molecule
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increases expression
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ISO
|
Diethylnitrosamine results in increased expression of CD40 mRNA
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CTD |
PMID:24535843 |
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NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
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| G
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Cd44
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CD44 molecule
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increases expression multiple interactions
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ISO EXP
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Diethylnitrosamine results in increased expression of CD44 mRNA epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]; theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CD44 protein]
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CTD |
PMID:19638242 PMID:21527772 PMID:27058323 |
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NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
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| G
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Cd46
|
CD46 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CD46 mRNA
|
CTD |
PMID:17602206 |
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NCBI chr13:109,104,122...109,134,903
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| G
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Cd47
|
Cd47 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CD47 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CD47 mRNA
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CTD |
PMID:17602206 PMID:18164116 |
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NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272
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| G
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Cd48
|
Cd48 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD48 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr13:86,717,960...86,741,540
Ensembl chr13:86,717,961...86,742,942
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| G
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Cd52
|
CD52 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD52 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086
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| G
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Cd63
|
Cd63 molecule
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multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD63 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CD63 mRNA Diethylnitrosamine results in increased expression of CD63 mRNA
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CTD |
PMID:12771043 PMID:18164116 PMID:28943392 |
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NCBI chr 7:1,909,538...1,924,937
Ensembl chr 7:1,922,169...1,924,938
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| G
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Cd68
|
Cd68 molecule
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CD68 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540
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| G
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Cd74
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CD74 molecule
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increases expression multiple interactions
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EXP
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Diethylnitrosamine results in increased expression of CD74 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CD74 mRNA
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CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410
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| G
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Cd80
|
Cd80 molecule
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decreases expression
|
EXP
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Diethylnitrosamine results in decreased expression of CD80 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
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|
| G
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Cd86
|
CD86 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CD86 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
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| G
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Cd8a
|
CD8 subunit alpha
|
multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of CD8A mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CD8A mRNA
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CTD |
PMID:23830814 |
|
NCBI chr 4:104,924,116...104,928,353
Ensembl chr 4:104,900,833...104,928,358
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| G
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Cd9
|
CD9 molecule
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multiple interactions
|
EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD9 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444
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| G
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Cd93
|
CD93 molecule
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CD93 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:156,345,019...156,351,537
Ensembl chr 3:156,345,019...156,351,537
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| G
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Cdc20
|
cell division cycle 20
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multiple interactions increases expression
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ISO EXP
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC20 mRNA] [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDC20 mRNA
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CTD |
PMID:17854601 PMID:18164116 PMID:19638242 PMID:21295105 PMID:24535843 |
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NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799
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| G
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Cdc25b
|
cell division cycle 25B
|
multiple interactions increases expression
|
ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDC25B protein; AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC25B mRNA]; FOXM1 protein affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDC25B protein]
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CTD |
PMID:15082532 PMID:19996281 |
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NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492
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|
| G
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Cdc25c
|
cell division cycle 25C
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CDC25C mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDC25C protein; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC25C mRNA]
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CTD |
PMID:15082532 PMID:17854601 |
|
NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292
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|
| G
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Cdc34
|
cell division cycle 34, ubiquitin conjugating enzyme
|
multiple interactions
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ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CDC34 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 7:10,668,209...10,674,206
Ensembl chr 7:10,668,210...10,674,526
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| G
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Cdc37
|
cell division cycle 37, HSP90 cochaperone
|
multiple interactions
|
EXP
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[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDC37 protein; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDC37 mRNA
|
CTD |
PMID:16317707 PMID:17602206 |
|
NCBI chr 8:27,954,292...27,966,935
Ensembl chr 8:27,948,016...27,983,931
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| G
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Cdc42bpa
|
CDC42 binding protein kinase alpha
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDC42BPA mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681
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|
| G
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Cdc42bpb
|
CDC42 binding protein kinase beta
|
multiple interactions
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ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CDC42BPB gene
|
CTD |
PMID:23968726 |
|
NCBI chr 6:136,154,905...136,241,259
Ensembl chr 6:136,154,905...136,237,570
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| G
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Cdc45
|
cell division cycle 45
|
increases expression multiple interactions
|
ISO
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Diethylnitrosamine results in increased expression of CDC45 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC45 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981
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| G
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Cdc5l
|
cell division cycle 5-like
|
increases expression
|
EXP
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Diethylnitrosamine results in increased expression of CDC5L mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899
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|
| G
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Cdc6
|
cell division cycle 6
|
multiple interactions increases expression
|
ISO
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RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDC6 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241
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| G
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Cdca3
|
cell division cycle associated 3
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDCA3 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA3 mRNA]
|
CTD |
PMID:17854601 PMID:24535843 |
|
NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068
|
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| G
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Cdca5
|
cell division cycle associated 5
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CDCA5 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA5 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 1:212,807,863...212,821,313
Ensembl chr 1:212,804,014...212,821,309
|
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| G
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Cdca7
|
cell division cycle associated 7
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CDCA7 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA7 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947
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| G
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Cdca8
|
cell division cycle associated 8
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CDCA8 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDCA8 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CDCA8 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDCA8 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDCA8 mRNA]
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CTD |
PMID:17854601 PMID:18164116 PMID:22129741 PMID:24535843 |
|
NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283
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|
| G
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Cdh1
|
cadherin 1
|
increases expression increases expression multiple interactions decreases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CDH1 mRNA; Diethylnitrosamine results in increased expression of CDH1 protein N-nitrosodiethylamine co-treated with atorvastatin increases expression of Cdh1 mRNA in liver epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in decreased expression of CDH1 mRNA]; theaflavin inhibits the reaction [Diethylnitrosamine results in decreased expression of CDH1 mRNA]
|
CTD RGD |
PMID:24535843 PMID:25319454 PMID:27058323 PMID:25319454 |
RGD:152995431 |
NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
|
|
| G
|
Cdh11
|
cadherin 11
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH11 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDH11 mRNA
|
CTD |
PMID:18164116 PMID:22129741 |
|
NCBI chr19:2,152,961...2,312,140
Ensembl chr19:2,154,840...2,312,140
|
|
| G
|
Cdh13
|
cadherin 13
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH13 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119
|
|
| G
|
Cdh17
|
cadherin 17
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDH17 mRNA Diethylnitrosamine results in increased expression of CDH17 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226
|
|
| G
|
Cdh2
|
cadherin 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CDH2 gene
|
CTD |
PMID:21163286 |
|
NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
|
|
| G
|
Cdh3
|
cadherin 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257
|
|
| G
|
Cdh4
|
cadherin 4
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CDH4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 3:186,902,763...187,381,020
Ensembl chr 3:186,902,751...187,381,020
|
|
| G
|
Cdhr2
|
cadherin-related family member 2
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDHR2 mRNA Diethylnitrosamine results in increased expression of CDHR2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr17:9,881,979...9,917,698
Ensembl chr17:9,881,979...9,917,698
|
|
| G
|
Cdhr5
|
cadherin-related family member 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDHR5 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:205,802,686...205,811,184
Ensembl chr 1:205,802,686...205,811,093
|
|
| G
|
Cdk1
|
cyclin-dependent kinase 1
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CDK1 mRNA; Diethylnitrosamine results in increased expression of CDK1 protein [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK1 protein; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK1 protein [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK1 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK1 mRNA]
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CTD |
PMID:12616621 PMID:17854601 PMID:18164116 PMID:19638242 PMID:19887370 PMID:24535843 More...
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NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
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| G
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Cdk2
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cyclin dependent kinase 2
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increases expression multiple interactions affects expression
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EXP ISO
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Diethylnitrosamine results in increased expression of CDK2 protein Hesperidin inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 protein] Diethylnitrosamine affects the expression of CDK2 protein Diethylnitrosamine results in increased expression of CDK2 mRNA; Diethylnitrosamine results in increased expression of CDK2 protein [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein; CDKN1B protein inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2 mRNA]
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CTD |
PMID:11831363 PMID:17620307 PMID:17854601 PMID:26589970 PMID:30779474 |
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NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
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| G
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Cdk2ap2
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cyclin-dependent kinase 2 associated protein 2
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multiple interactions increases expression
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ISO
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MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2AP2 mRNA]
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CTD |
PMID:17942915 |
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NCBI chr 1:210,819,155...210,822,604
Ensembl chr 1:210,820,507...210,823,010
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| G
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Cdk4
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cyclin-dependent kinase 4
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multiple interactions increases expression
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDK4 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 protein; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA; [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein; thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of CDK4 protein]
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CTD |
PMID:11831363 PMID:12616621 PMID:17602206 PMID:19822196 PMID:24012840 PMID:26589970 More...
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NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
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| G
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Cdk5rap2
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CDK5 regulatory subunit associated protein 2
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CDK5RAP2 mRNA
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CTD |
PMID:19041683 |
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NCBI chr 5:88,807,402...88,976,005
Ensembl chr 5:88,807,402...88,976,069
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| G
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Cdk6
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cyclin-dependent kinase 6
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multiple interactions
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EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CDK6 mRNA
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CTD |
PMID:22129741 |
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NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701
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| G
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Cdkl3
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cyclin-dependent kinase-like 3
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multiple interactions
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EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CDKL3 mRNA
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CTD |
PMID:22129741 |
|
NCBI chr10:36,755,413...36,850,197
Ensembl chr10:36,764,377...36,878,660
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| G
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Cdkn1a
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cyclin-dependent kinase inhibitor 1A
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multiple interactions increases expression decreases expression
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ISO EXP
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[Diethylnitrosamine co-treated with Cholic Acid] results in decreased expression of CDKN1A protein; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A mRNA]; RB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A mRNA]; salvianolic acid B inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; salvianolic acid B inhibits the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] Diethylnitrosamine results in increased expression of CDKN1A mRNA; Diethylnitrosamine results in increased expression of CDKN1A protein 2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of CDKN1A protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDKN1A mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CDKN1A mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA; IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA]; lanreotide promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A mRNA]; Pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; Pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]; pyrazolanthrone promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] Diethylnitrosamine results in decreased expression of CDKN1A mRNA; Diethylnitrosamine results in decreased expression of CDKN1A protein
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CTD |
PMID:11003613 PMID:14633663 PMID:17582756 PMID:17917374 PMID:18164116 PMID:18253720 PMID:18282651 PMID:18544905 PMID:19100860 PMID:19418558 PMID:19822196 PMID:19874807 PMID:19996281 PMID:21607683 PMID:21813463 PMID:22129741 PMID:24012840 PMID:24535843 PMID:25242409 PMID:27151938 PMID:33290806 More...
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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| G
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Cdkn1b
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cyclin-dependent kinase inhibitor 1B
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multiple interactions decreases expression
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EXP ISO
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2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDKN1B mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA; Pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]]; Pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein] CDKN1B protein inhibits the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDK2 protein]; CDKN1B results in decreased susceptibility to [Diethylnitrosamine co-treated with Phenobarbital]
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CTD |
PMID:17582756 PMID:17602206 PMID:17620307 PMID:18253720 PMID:18544905 |
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NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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| G
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Cdkn1c
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cyclin-dependent kinase inhibitor 1C
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of CDKN1C mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDKN1C mRNA]
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CTD |
PMID:17854601 |
|
NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
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| G
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Cdkn2a
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cyclin-dependent kinase inhibitor 2A
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multiple interactions decreases expression increases methylation increases expression
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ISO EXP
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[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDKN2A protein; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDKN2A protein] Diethylnitrosamine results in decreased expression of CDKN2A mRNA Diethylnitrosamine results in increased methylation of CDKN2A promoter Diethylnitrosamine results in increased expression of CDKN2A mRNA; Diethylnitrosamine results in increased expression of CDKN2A protein [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A mRNA; [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CDKN2A protein; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDKN2A mRNA; Betaine promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA]; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2A mRNA]
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CTD |
PMID:15082532 PMID:16317707 PMID:17602206 PMID:19642983 PMID:19919837 PMID:20360939 PMID:23288052 PMID:24535843 More...
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NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
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| G
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Cdkn2b
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cyclin-dependent kinase inhibitor 2B
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decreases expression increases expression multiple interactions
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ISO EXP
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Diethylnitrosamine results in decreased expression of CDKN2B mRNA Diethylnitrosamine results in increased expression of CDKN2B mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA] IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2B mRNA]
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CTD |
PMID:18691550 PMID:21295105 PMID:24535843 |
|
NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855
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| G
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Cdkn2c
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cyclin-dependent kinase inhibitor 2C
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multiple interactions increases expression decreases expression
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ISO EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDKN2C mRNA; AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2C mRNA] Diethylnitrosamine results in increased expression of CDKN2C mRNA [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNA
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CTD |
PMID:18282651 PMID:19996281 PMID:20360939 PMID:24535843 |
|
NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
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| G
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Cdkn2d
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cyclin dependent kinase inhibitor 2D
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decreases expression multiple interactions
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ISO
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Diethylnitrosamine results in decreased expression of CDKN2D mRNA RB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN2D mRNA]
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CTD |
PMID:18282651 |
|
NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809
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| G
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Cdkn3
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cyclin-dependent kinase inhibitor 3
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multiple interactions increases expression
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CDKN3 mRNA Diethylnitrosamine results in increased expression of CDKN3 mRNA
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CTD |
PMID:24535843 |
|
NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722
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| G
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Cdo1
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cysteine dioxygenase type 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CDO1 mRNA
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CTD |
PMID:28943392 |
|
NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891
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| G
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Cdr2
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cerebellar degeneration-related protein 2
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDR2 mRNA
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CTD |
PMID:18164116 |
|
NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863
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| G
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Cdt1
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chromatin licensing and DNA replication factor 1
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of CDT1 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDT1 mRNA]
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CTD |
PMID:17854601 |
|
NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194
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| G
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Cdx2
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caudal type homeo box 2
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDX2 mRNA
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CTD |
PMID:18164116 |
|
NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246
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| G
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Ceacam1
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CEA cell adhesion molecule 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CEACAM1 mRNA
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CTD |
PMID:18164116 |
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NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798
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| G
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Ceacam20
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CEA cell adhesion molecule 20
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multiple interactions increases expression
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EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CEACAM20 mRNA; citral inhibits the reaction [Diethylnitrosamine results in increased expression of CEACAM20 protein]
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CTD |
PMID:22129741 PMID:32302048 |
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NCBI chr 1:88,750,010...88,771,679
Ensembl chr 1:88,750,000...88,772,779
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| G
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Ceacam4
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CEA cell adhesion molecule 4
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CEACAM10 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CEACAM10 mRNA
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CTD |
PMID:20360939 PMID:22129741 |
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NCBI chr 1:89,504,555...89,510,831
Ensembl chr 1:89,504,555...89,510,831
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| G
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Cebpa
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CCAAT/enhancer binding protein alpha
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decreases expression
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ISO EXP
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Diethylnitrosamine results in decreased expression of CEBPA mRNA
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CTD |
PMID:19638242 PMID:21527772 |
|
NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
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| G
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Cebpz
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CCAAT/enhancer binding protein zeta
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CEBPZ mRNA
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CTD |
PMID:19041683 |
|
NCBI chr 6:21,872,071...21,889,755
Ensembl chr 6:21,872,025...21,889,749
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| G
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Cela1
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chymotrypsin like elastase 1
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multiple interactions decreases expression
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELA1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CELA1 mRNA Diethylnitrosamine results in decreased expression of CELA1 mRNA
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CTD |
PMID:18164116 PMID:19638242 PMID:28943392 |
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NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:133,651,941...133,665,061
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| G
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Celsr1
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cadherin, EGF LAG seven-pass G-type receptor 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELSR1 mRNA
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CTD |
PMID:18164116 |
|
NCBI chr 7:118,867,450...119,004,859
Ensembl chr 7:118,867,450...119,004,856
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| G
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Celsr2
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cadherin, EGF LAG seven-pass G-type receptor 2
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of CELSR2 mRNA
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CTD |
PMID:24535843 |
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NCBI chr 2:198,717,333...198,741,689
Ensembl chr 2:198,717,896...198,741,581
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| G
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Cenpa
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centromere protein A
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multiple interactions increases expression
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ISO
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RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CENPA mRNA]
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CTD |
PMID:17854601 PMID:24535843 |
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NCBI chr 6:31,420,062...31,431,703
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| G
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Cenpc
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centromere protein C
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CENPC1 mRNA
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CTD |
PMID:19041683 |
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NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590
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| G
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Cenpf
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centromere protein F
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multiple interactions
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EXP ISO
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CENPF mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CENPF mRNA
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CTD |
PMID:22129741 PMID:24535843 |
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NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886
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| G
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Cenpi
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centromere protein I
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CENPI mRNA
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CTD |
PMID:18164116 |
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NCBI chr X:101,809,192...101,860,935
Ensembl chr X:101,809,659...101,860,934
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| G
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Cenpk
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centromere protein K
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multiple interactions
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EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CENPK mRNA
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CTD |
PMID:22129741 |
|
NCBI chr 2:37,094,163...37,155,158
Ensembl chr 2:37,094,248...37,119,488
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| G
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Cenpl
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centromere protein L
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multiple interactions
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CENPL mRNA
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CTD |
PMID:24535843 |
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NCBI chr13:75,870,479...75,885,466
Ensembl chr13:75,870,489...75,905,250
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| G
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Cenpp
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centromere protein P
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multiple interactions
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CENPP mRNA
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CTD |
PMID:24535843 |
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NCBI chr17:15,220,521...15,395,741
Ensembl chr17:15,220,291...15,395,739
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| G
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Cep55
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centrosomal protein 55
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multiple interactions
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ISO
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[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CEP55 mRNA
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CTD |
PMID:24535843 |
|
NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890
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| G
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Cep76
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centrosomal protein 76
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multiple interactions
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EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CEP76 mRNA
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CTD |
PMID:22129741 |
|
NCBI chr18:63,444,389...63,478,358
Ensembl chr18:63,443,746...63,478,358
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| G
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Cers2
|
ceramide synthase 2
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CERS2 mRNA
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CTD |
PMID:20387270 |
|
NCBI chr 2:185,579,511...185,587,789
Ensembl chr 2:185,579,119...185,588,839
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| G
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Cers4
|
ceramide synthase 4
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increases expression
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EXP
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Diethylnitrosamine results in increased expression of CERS4 mRNA
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CTD |
PMID:20387270 |
|
NCBI chr12:7,649,610...7,688,066
Ensembl chr12:7,649,610...7,688,070
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|
| G
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Cers6
|
ceramide synthase 6
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increases expression
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ISO
|
Diethylnitrosamine results in increased expression of LASS6 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:74,038,520...74,287,544
Ensembl chr 3:74,038,851...74,287,544
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|
| G
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Ces1d
|
carboxylesterase 1D
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multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CES1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CES1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA Diethylnitrosamine results in decreased expression of CES1D mRNA [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CES1D protein; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CES1D protein
|
CTD |
PMID:17602206 PMID:18253720 PMID:18544905 PMID:19041683 PMID:23457121 |
|
NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
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|
| G
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Ces1e
|
carboxylesterase 1E
|
multiple interactions
|
EXP
|
[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of CES1E protein
|
CTD |
PMID:20935162 |
|
NCBI chr19:30,006,173...30,042,628
Ensembl chr19:30,006,153...30,042,626
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|
| G
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Ces2a
|
carboxylesterase 2A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CES2A mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:135,885...142,935
Ensembl chr19:135,885...142,935
|
|
| G
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Ces2c
|
carboxylesterase 2C
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CES2C mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:270,374,913...270,384,801
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| G
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Ces2e
|
carboxylesterase 2E
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CES2E mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CES2E mRNA
|
CTD |
PMID:18164116 PMID:21607683 PMID:24535843 |
|
NCBI chr19:163,899...179,274
Ensembl chr19:163,859...179,308
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| G
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Ces2h
|
carboxylesterase 2H
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increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CES2 mRNA
|
CTD |
PMID:21813463 |
|
NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752
|
|
| G
|
Cfap45
|
cilia and flagella associated protein 45
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFAP45 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr13:87,521,831...87,545,236
Ensembl chr13:87,521,518...87,545,234
|
|
| G
|
Cfb
|
complement factor B
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CFB mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740
|
|
| G
|
Cfdp1
|
craniofacial development protein 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFDP1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:56,627,596...56,733,099
Ensembl chr19:56,626,963...56,733,098
|
|
| G
|
Cfh
|
complement factor H
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CFH mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532
|
|
| G
|
Cfhr1
|
complement factor H-related 1
|
decreases expression
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of CFHR1 mRNA
|
CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr13:53,946,298...53,961,282
Ensembl chr13:53,919,927...53,961,303
|
|
| G
|
Cfl1
|
cofilin 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CFL1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
|
|
| G
|
Cgm4
|
carcinoembryonic antigen gene family 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CGM4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:86,904,526...86,917,487
Ensembl chr 1:86,904,526...86,917,475
|
|
| G
|
Cgn
|
cingulin
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CGN gene
|
CTD |
PMID:23968726 |
|
NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635
|
|
| G
|
Cgref1
|
cell growth regulator with EF hand domain 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CGREF1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800
|
|
| G
|
Ch25h
|
cholesterol 25-hydroxylase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CH25H mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190
|
|
| G
|
Chaf1b
|
chromatin assembly factor 1 subunit B
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHAF1B mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733
|
|
| G
|
Champ1
|
chromosome alignment maintaining phosphoprotein 1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CHAMP1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr16:82,436,172...82,447,144
Ensembl chr16:82,434,823...82,458,984
|
|
| G
|
Chat
|
choline O-acetyltransferase
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CHAT mRNA
|
CTD |
PMID:19542621 |
|
NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416
|
|
| G
|
Chchd3
|
coiled-coil-helix-coiled-coil-helix domain containing 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CHCHD3 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 4:62,327,574...62,584,085
Ensembl chr 4:62,327,576...62,584,035
|
|
| G
|
Chchd6
|
coiled-coil-helix-coiled-coil-helix domain containing 6
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CHCHD6 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHCHD6 mRNA
|
CTD |
PMID:17602206 PMID:22129741 |
|
NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421
|
|
| G
|
Chdh
|
choline dehydrogenase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHDH mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr16:5,199,738...5,232,067
Ensembl chr16:5,200,763...5,232,997
|
|
| G
|
Chek1
|
checkpoint kinase 1
|
multiple interactions increases expression
|
ISO EXP
|
ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 mRNA]; ATM protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 protein]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CHEK1 mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK1 mRNA Diethylnitrosamine results in increased expression of CHEK1 mRNA; Diethylnitrosamine results in increased expression of CHEK1 protein
|
CTD |
PMID:17854601 PMID:19919837 PMID:22129741 |
|
NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
|
|
| G
|
Chek2
|
checkpoint kinase 2
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA; [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA]
|
CTD |
PMID:18253720 PMID:18544905 PMID:22129741 |
|
NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
|
|
| G
|
Cherp
|
calcium homeostasis endoplasmic reticulum protein
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CHERP mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549
|
|
| G
|
Chka
|
choline kinase alpha
|
multiple interactions increases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHKA mRNA Diethylnitrosamine results in increased expression of CHKA mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752
|
|
| G
|
Chmp4c
|
charged multivesicular body protein 4C
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CHMP4C mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:93,299,152...93,336,075
Ensembl chr 2:93,299,157...93,360,850
|
|
| G
|
Chpf
|
chondroitin polymerizing factor
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHPF mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CHPF mRNA
|
CTD |
PMID:18164116 PMID:28943392 |
|
NCBI chr 9:84,411,824...84,416,523
Ensembl chr 9:84,411,829...84,416,523
|
|
| G
|
Chrdl1
|
chordin-like 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CHRDL1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr X:111,685,864...111,789,684
Ensembl chr X:111,685,866...111,789,661
|
|
| G
|
Chrm2
|
cholinergic receptor, muscarinic 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHRM2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464
|
|
| G
|
Chrna2
|
cholinergic receptor nicotinic alpha 2 subunit
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CHRNA2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144
|
|
| G
|
Chrna4
|
cholinergic receptor nicotinic alpha 4 subunit
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CHRNA4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105
|
|
| G
|
Chrna7
|
cholinergic receptor nicotinic alpha 7 subunit
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CHRNA7 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858
|
|
| G
|
Chrnb1
|
cholinergic receptor nicotinic beta 1 subunit
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHRNB1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr10:54,999,943...55,015,137
Ensembl chr10:55,002,788...55,015,107
|
|
| G
|
Chrne
|
cholinergic receptor nicotinic epsilon subunit
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CHRNE mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:55,829,835...55,838,853
Ensembl chr10:55,829,836...55,834,154
|
|
| G
|
Chst12
|
carbohydrate sulfotransferase 12
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CHST12 gene
|
CTD |
PMID:23968726 |
|
NCBI chr12:19,224,545...19,243,012
Ensembl chr12:19,220,141...19,243,047
|
|
| G
|
Chst13
|
carbohydrate sulfotransferase 13
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CHST13 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 4:124,381,226...124,395,143
Ensembl chr 4:124,381,226...124,395,143
|
|
| G
|
Chst14
|
carbohydrate sulfotransferase 14
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of CHST14 promoter; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CHST14 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHST14 mRNA
|
CTD |
PMID:22129741 PMID:25374375 |
|
NCBI chr 3:126,370,348...126,372,405
Ensembl chr 3:126,370,348...126,372,777
|
|
| G
|
Chst4
|
carbohydrate sulfotransferase 4
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CHST4 mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr19:54,900,914...54,911,735
Ensembl chr19:54,882,719...54,916,648
|
|
| G
|
Chst6
|
carbohydrate sulfotransferase 6
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CHST6 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr19:56,769,991...56,790,276
Ensembl chr19:56,769,967...56,790,306
|
|
| G
|
Chst8
|
carbohydrate sulfotransferase 8
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA
|
CTD |
PMID:18253720 |
|
NCBI chr 1:96,431,144...96,572,880
Ensembl chr 1:96,431,145...96,572,880
|
|
| G
|
Chsy3
|
chondroitin sulfate synthase 3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CHSY3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr18:54,842,260...55,096,008
Ensembl chr18:54,842,180...55,095,981
|
|
| G
|
Chuk
|
component of inhibitor of nuclear factor kappa B kinase complex
|
increases activity
|
ISO
|
Diethylnitrosamine results in increased activity of CHUK protein
|
CTD |
PMID:15989949 |
|
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
|
|
| G
|
Cib2
|
calcium and integrin binding family member 2
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of CIB2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CIB2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:63,826,410...63,843,301
Ensembl chr 8:63,826,411...63,843,277
|
|
| G
|
Cib3
|
calcium and integrin binding family member 3
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CIB3 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CIB3 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr16:17,656,453...17,665,848
Ensembl chr16:17,656,453...17,665,848
|
|
| G
|
Cidea
|
cell death-inducing DFFA-like effector a
|
multiple interactions increases expression
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CIDEA mRNA Diethylnitrosamine results in increased expression of CIDEA mRNA
|
CTD |
PMID:22129741 PMID:24535843 |
|
NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382
|
|
| G
|
Cidec
|
cell death-inducing DFFA-like effector c
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CIDEC mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806
|
|
| G
|
Cimap1a
|
ciliary microtubule associated protein 1A
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CIMAP1A mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:205,355,601...205,358,882
Ensembl chr 1:205,355,675...205,358,882
|
|
| G
|
Cimap1b
|
ciliary microtubule associated protein 1B
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CIMAP1B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:122,323,860...122,326,921
Ensembl chr 7:122,323,860...122,326,876
|
|
| G
|
Cish
|
cytokine inducible SH2-containing protein
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CISH mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986
|
|
| G
|
Cited1
|
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CITED1 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr X:71,390,328...71,395,023
Ensembl chr X:71,390,331...71,393,649
|
|
| G
|
Cited2
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CITED2 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CITED2 mRNA MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CITED2 mRNA]
|
CTD |
PMID:18164116 PMID:18691550 |
|
NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782
|
|
| G
|
Cited4
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CITED4 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 5:139,532,165...139,533,056
Ensembl chr 5:139,531,584...139,533,361
|
|
| G
|
Ckap2
|
cytoskeleton associated protein 2
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CKAP2 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKAP2 mRNA]
|
CTD |
PMID:17854601 PMID:24535843 |
|
NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352
|
|
| G
|
Ckap4
|
cytoskeleton-associated protein 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CKAP4 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CKAP4 mRNA
|
CTD |
PMID:22129741 PMID:28943392 |
|
NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624
|
|
| G
|
Cks1b
|
CDC28 protein kinase regulatory subunit 1B
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CKS1B mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKS1B mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365
|
|
| G
|
Cks2
|
CDC28 protein kinase regulatory subunit 2
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CKS2 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CKS2 mRNA]
|
CTD |
PMID:17854601 PMID:25242409 |
|
NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519
|
|
| G
|
Clcf1
|
cardiotrophin-like cytokine factor 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CLCF1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064
|
|
| G
|
Clcn1
|
chloride voltage-gated channel 1
|
multiple interactions increases expression
|
EXP
|
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CLCN1 mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr 4:72,138,739...72,168,113
Ensembl chr 4:72,139,162...72,168,128
|
|
| G
|
Clcn2
|
chloride voltage-gated channel 2
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CLCN2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059
|
|
| G
|
Clcn5
|
chloride voltage-gated channel 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLCN5 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr X:17,857,260...18,011,844
Ensembl chr X:17,857,260...18,011,844
|
|
| G
|
Cldn1
|
claudin 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLDN1 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CLDN1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLDN1 mRNA
|
CTD |
PMID:17602206 PMID:18164116 PMID:22129741 |
|
NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
|
|
| G
|
Cldn15
|
claudin 15
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CLDN15 gene
|
CTD |
PMID:23968726 |
|
NCBI chr12:25,334,849...25,345,104
Ensembl chr12:25,334,849...25,343,477
|
|
| G
|
Cldn16
|
claudin 16
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CLDN16 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr11:87,795,106...87,814,396
Ensembl chr11:87,795,106...87,814,396
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|
| G
|
Cldn7
|
claudin 7
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CLDN7 mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA Diethylnitrosamine results in increased expression of CLDN7 mRNA
|
CTD |
PMID:18164116 PMID:20360939 PMID:24535843 |
|
NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905
|
|
| G
|
Clec1b
|
C-type lectin domain family 1, member B
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CLEC1B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:164,533,987...164,542,320
Ensembl chr 4:164,534,055...164,542,867
|
|
| G
|
Clec4a3
|
C-type lectin domain family 4, member A3
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CLEC4A3 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:157,885,899...157,896,728
Ensembl chr 4:157,885,895...157,896,727
|
|
| G
|
Clec4f
|
C-type lectin domain family 4, member F
|
decreases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of CLEC4F mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CLEC4F mRNA
|
CTD |
PMID:19041683 PMID:24535843 |
|
NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438
|
|
| G
|
Clec9a
|
C-type lectin domain containing 9A
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLEC9A mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 4:164,546,323...164,561,380
Ensembl chr 4:164,546,311...164,561,380
|
|
| G
|
Clic1
|
chloride intracellular channel 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CLIC1 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367
|
|
| G
|
Clic2
|
chloride intracellular channel 2
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CLIC2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr20:154,630...169,655
Ensembl chr20:154,255...169,648
|
|
| G
|
Clic5
|
chloride intracellular channel 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLIC5 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780
|
|
| G
|
Clns1a
|
chloride nucleotide-sensitive channel 1A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CLNS1A mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:161,429,437...161,450,904
Ensembl chr 1:161,421,808...161,450,902
|
|
| G
|
Clock
|
clock circadian regulator
|
multiple interactions increases response to substance increases expression
|
ISO EXP
|
CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP3 protein]; CLOCK protein promotes the reaction [Diethylnitrosamine results in increased activity of CASP7 protein]; CLOCK protein promotes the reaction [Diethylnitrosamine results in increased expression of and results in increased phosphorylation of TRP53 protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CLOCK mRNA] [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLOCK mRNA CLOCK protein results in increased susceptibility to Diethylnitrosamine
|
CTD |
PMID:17942915 PMID:20360939 PMID:21167249 |
|
NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872
|
|
| G
|
Clpx
|
caseinolytic mitochondrial matrix peptidase chaperone subunit X
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLPX mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762
|
|
| G
|
Clu
|
clusterin
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CLU mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CLU mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CLU mRNA
|
CTD |
PMID:14656948 PMID:16158176 PMID:18544905 |
|
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
|
|
| G
|
Clybl
|
citramalyl-CoA lyase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLYBL mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CLYBL mRNA
|
CTD |
PMID:17602206 PMID:18164116 |
|
NCBI chr15:105,690,283...105,912,347
Ensembl chr15:105,690,295...105,912,345
|
|
| G
|
Cma1
|
chymase 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CMA1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133
|
|
| G
|
Cmbl
|
carboxymethylenebutenolidase homolog
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CMBL mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880
|
|
| G
|
Cmtm6
|
CKLF-like MARVEL transmembrane domain containing 6
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the expression of and affects the localization of CMTM6 protein; [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of CMTM6 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230
|
|
| G
|
Cnmd
|
chondromodulin
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CNMD mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr15:61,450,617...61,475,382
Ensembl chr15:61,450,450...61,475,350
|
|
| G
|
Cnn3
|
calponin 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNN3 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 2:212,203,661...212,234,772
Ensembl chr 2:212,226,640...212,234,815
|
|
| G
|
Cnp
|
2',3'-cyclic nucleotide 3' phosphodiesterase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNP1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr10:86,011,504...86,018,063
Ensembl chr10:86,011,495...86,018,063
|
|
| G
|
Cntnap2
|
contactin associated protein 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CNTNAP2 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:75,109,858...77,366,258
|
|
| G
|
Cobl
|
cordon-bleu WH2 repeat protein
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COBL mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257
|
|
| G
|
Col16a1
|
collagen type XVI alpha 1 chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL16A1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011
|
|
| G
|
Col18a1
|
collagen type XVIII alpha 1 chain
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL18A1 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of COL18A1 mRNA Diethylnitrosamine results in decreased expression of COL18A1 mRNA
|
CTD |
PMID:17602206 PMID:18164116 PMID:19638242 |
|
NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112
|
|
| G
|
Col1a1
|
collagen type I alpha 1 chain
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of COL1A1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL1A1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of COL1A1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of COL1A1 promoter; [Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] affects the expression of COL1A1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:20045035 PMID:21295105 PMID:23830814 PMID:25374375 PMID:28943392 More...
|
|
NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
|
|
| G
|
Col1a2
|
collagen type I alpha 2 chain
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of COL1A2 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of COL1A2 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
|
|
| G
|
Col26a1
|
collagen type XXVI alpha 1 chain
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of COL26A1 gene
|
CTD |
PMID:23968726 |
|
NCBI chr12:25,429,362...25,575,205
Ensembl chr12:25,429,387...25,575,206
|
|
| G
|
Col27a1
|
collagen type XXVII alpha 1 chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL27A1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:81,662,822...81,781,502
Ensembl chr 5:81,661,685...81,781,502
|
|
| G
|
Col3a1
|
collagen type III alpha 1 chain
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of COL3A1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
|
|
| G
|
Col4a1
|
collagen type IV alpha 1 chain
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNA Diethylnitrosamine results in increased expression of COL4A1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:24535843 |
|
NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482
|
|
| G
|
Col4a2
|
collagen type IV alpha 2 chain
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COL4A2 mRNA
|
CTD |
PMID:12771043 |
|
NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520
|
|
| G
|
Col4a3
|
collagen type IV alpha 3 chain
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COL4A3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 9:91,323,990...91,453,088
Ensembl chr 9:91,323,990...91,453,077
|
|
| G
|
Col4a4
|
collagen type IV alpha 4 chain
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COL4A4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 9:91,281,324...91,323,577
Ensembl chr 9:91,203,670...91,323,577
|
|
| G
|
Col4a5
|
collagen type IV alpha 5 chain
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COL4A5 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214
|
|
| G
|
Col5a2
|
collagen type V alpha 2 chain
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of COL5A2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150
|
|
| G
|
Col6a1
|
collagen type VI alpha 1 chain
|
multiple interactions increases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of COL6A1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107
|
|
| G
|
Col6a2
|
collagen type VI alpha 2 chain
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL6A2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042
|
|
| G
|
Colec10
|
collectin subfamily member 10
|
multiple interactions decreases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of COLEC10 mRNA Diethylnitrosamine results in decreased expression of COLEC10 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:87,634,686...87,695,465
Ensembl chr 7:87,634,654...87,699,534
|
|
| G
|
Colec11
|
collectin sub-family member 11
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COLEC11 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 6:50,952,357...50,984,845
Ensembl chr 6:50,952,357...50,999,493
|
|
| G
|
Colec12
|
collectin sub-family member 12
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COLEC12 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297
|
|
| G
|
Colq
|
collagen like tail subunit of asymmetric acetylcholinesterase
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of COLQ mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of COLQ mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of COLQ mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr16:6,738,251...6,830,492
Ensembl chr16:6,738,251...6,793,501
|
|
| G
|
Commd3
|
COMM domain containing 3
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of COMMD3 gene
|
CTD |
PMID:23968726 |
|
NCBI chr17:86,235,863...86,239,610
Ensembl chr17:86,235,863...86,239,610
|
|
| G
|
Comt
|
catechol-O-methyltransferase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of COMT mRNA
|
CTD |
PMID:18544905 |
|
NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
|
|
| G
|
Coq3
|
coenzyme Q3 methyltransferase
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of COQ3 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 5:40,226,313...40,257,383
Ensembl chr 5:40,226,368...40,257,617
|
|
| G
|
Coq6
|
coenzyme Q6 monooxygenase
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of COQ6 mRNA
|
CTD |
PMID:16158176 |
|
NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310
|
|
| G
|
Coq8a
|
coenzyme Q8A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of COQ8A mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of COQ8A mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of COQ8A mRNA
|
CTD |
PMID:17602206 PMID:18164116 PMID:28943392 |
|
NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378
|
|
| G
|
Coq8b
|
coenzyme Q8B
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COQ8B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:91,653,241...91,676,822
Ensembl chr 1:91,654,225...91,676,819
|
|
| G
|
Corin
|
corin, serine peptidase
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CORIN mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649
|
|
| G
|
Coro1a
|
coronin 1A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CORO1A mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102
|
|
| G
|
Coro6
|
coronin 6
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CORO6 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,809,689...62,817,787
|
|
| G
|
Cotl1
|
coactosin-like F-actin binding protein 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of COTL1 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840
|
|
| G
|
Cox4i2
|
cytochrome c oxidase subunit 4i2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX4I2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 3:161,686,193...161,699,605
Ensembl chr 3:161,689,017...161,699,602
|
|
| G
|
Cox5b
|
cytochrome c oxidase subunit 5B
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of COX5B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403
|
|
| G
|
Cox6a2
|
cytochrome c oxidase subunit 6A2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of COX6A2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716
|
|
| G
|
Cox6b2
|
cytochrome c oxidase subunit 6B2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COX6B2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:78,122,871...78,124,096
Ensembl chr 1:78,122,453...78,124,094
|
|
| G
|
Cox6c
|
cytochrome c oxidase subunit 6C
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of COX6C protein [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of COX6C protein
|
CTD |
PMID:20935162 |
|
NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166
|
|
| G
|
Cox7a2
|
cytochrome c oxidase subunit 7A2
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of COX7A2 mRNA; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of COX7A2 mRNA]
|
CTD |
PMID:17602206 PMID:20360939 |
|
NCBI chr 8:89,597,051...89,611,032
Ensembl chr14:55,514,261...55,514,512 Ensembl chr 8:55,514,261...55,514,512
|
|
| G
|
Cp
|
ceruloplasmin
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of and results in increased activity of CP protein; Iron inhibits the reaction [Diethylnitrosamine results in increased expression of CP protein] Diethylnitrosamine results in increased expression of CP mRNA Diethylnitrosamine results in decreased expression of CP mRNA [Copper co-treated with Diethylnitrosamine] results in increased expression of CP protein
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CTD |
PMID:19061943 PMID:19638242 PMID:20302851 PMID:24535843 |
|
NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087
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| G
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Cpa1
|
carboxypeptidase A1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CPA1 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928
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|
| G
|
Cpe
|
carboxypeptidase E
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPE mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524
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|
| G
|
Cpeb2
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cytoplasmic polyadenylation element binding protein 2
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CPEB2 mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CPEB2 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CPEB2 mRNA]
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CTD |
PMID:17602206 PMID:17942915 |
|
NCBI chr14:71,999,958...72,056,012
Ensembl chr14:72,002,072...72,052,263
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|
| G
|
Cpeb4
|
cytoplasmic polyadenylation element binding protein 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CPEB4 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr10:16,222,271...16,284,248
Ensembl chr10:16,225,672...16,283,787
|
|
| G
|
Cplx1
|
complexin 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPLX1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr14:1,329,073...1,360,781
Ensembl chr14:1,329,032...1,360,769
|
|
| G
|
Cpne8
|
copine 8
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CPNE8 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:123,494,864...123,669,060
Ensembl chr 7:123,494,865...123,669,060
|
|
| G
|
Cpq
|
carboxypeptidase Q
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CPQ mRNA
|
CTD |
PMID:19041683 PMID:19638242 |
|
NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137
|
|
| G
|
Cps1
|
carbamoyl-phosphate synthase 1
|
multiple interactions
|
EXP ISO
|
[Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of CPS1 protein [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CPS1 mRNA
|
CTD |
PMID:20935162 PMID:24535843 |
|
NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734
|
|
| G
|
Cpsf3
|
cleavage and polyadenylation specific factor 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CPSF3 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136
|
|
| G
|
Cpt1b
|
carnitine palmitoyltransferase 1B
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPT1B mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036
|
|
| G
|
Cpz
|
carboxypeptidase Z
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPZ mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr14:79,448,242...79,471,557
Ensembl chr14:79,448,139...79,471,556
|
|
| G
|
Crabp1
|
cellular retinoic acid binding protein 1
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CRABP1 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 8:64,047,431...64,055,469
Ensembl chr 8:64,047,060...64,055,470
|
|
| G
|
Crabp2
|
cellular retinoic acid binding protein 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CRABP2 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:175,707,312...175,728,385
|
|
| G
|
Crat
|
carnitine O-acetyltransferase
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CRAT mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRAT mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRAT mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA
|
CTD |
PMID:12771043 PMID:18164116 PMID:18253720 PMID:22129741 |
|
NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
|
|
| G
|
Creb1
|
cAMP responsive element binding protein 1
|
multiple interactions
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of CREB1 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased phosphorylation of CREB1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [bisphenol A co-treated with Diethylnitrosamine] results in increased expression of and results in increased phosphorylation of CREB1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of and results in increased phosphorylation of CREB1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of CREB1 mRNA; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased phosphorylation of CREB1 protein; bisphenol A promotes the reaction [[Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of CREB1 protein]
|
CTD |
PMID:34186418 PMID:36608567 |
|
NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
|
|
| G
|
Creg1
|
cellular repressor of E1A-stimulated genes 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CREG mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272
|
|
| G
|
Creld2
|
cysteine-rich with EGF-like domains 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CRELD2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:121,788,754...121,796,230
Ensembl chr 7:121,788,745...121,796,228
|
|
| G
|
Crem
|
cAMP responsive element modulator
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CREM mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160
|
|
| G
|
Crisp2
|
cysteine-rich secretory protein 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRISP2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 9:27,604,024...27,628,520
Ensembl chr 9:27,604,257...27,629,870
|
|
| G
|
Crmp1
|
collapsin response mediator protein 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRMP1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr14:77,734,675...77,780,916
Ensembl chr14:77,734,675...77,780,916
|
|
| G
|
Crot
|
carnitine O-octanoyltransferase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CROT mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CROT mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CROT mRNA
|
CTD |
PMID:17602206 PMID:18164116 PMID:28943392 |
|
NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064
|
|
| G
|
Crp
|
C-reactive protein
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CRP mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CRP mRNA [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of CRP protein; [Gemcitabine co-treated with olsalazine] inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of CRP protein]; Gemcitabine inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of CRP protein]
|
CTD |
PMID:17602206 PMID:28943392 PMID:38798245 |
|
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
|
|
| G
|
Cryab
|
crystallin, alpha B
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CRYAB mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CRYAB mRNA Diethylnitrosamine results in increased expression of CRYAB mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:28943392 |
|
NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528
|
|
| G
|
Crybg2
|
crystallin beta-gamma domain containing 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CRYBG2 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:151,570,540...151,602,163
|
|
| G
|
Cryga
|
crystallin, gamma A
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRYGA mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYGA mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYGA mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr 9:73,975,914...74,006,614
Ensembl chr 9:73,975,914...74,003,290
|
|
| G
|
Cryge
|
crystallin, gamma E
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CRYGE mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 9:73,923,661...73,926,258
Ensembl chr 9:73,923,661...73,927,011
|
|
| G
|
Crygn
|
crystallin, gamma N
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CRYGN mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 4:11,286,475...11,294,002
Ensembl chr 4:11,286,475...11,294,002
|
|
| G
|
Cryl1
|
crystallin, lambda 1
|
multiple interactions increases expression
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of CRYL1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CRYL1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CRYL1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYL1 mRNA Diethylnitrosamine results in increased expression of CRYL1 mRNA
|
CTD |
PMID:14656948 PMID:16158176 PMID:19638242 PMID:22129741 PMID:28943392 |
|
NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563
|
|
| G
|
Crym
|
crystallin, mu
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CRYM mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:183,991,745...184,006,962
|
|
| G
|
Csad
|
cysteine sulfinic acid decarboxylase
|
multiple interactions decreases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CSAD mRNA Diethylnitrosamine results in decreased expression of CSAD mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581
|
|
| G
|
Csf2
|
colony stimulating factor 2
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA
|
CTD |
PMID:18253720 |
|
NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031
|
|
| G
|
Csk
|
C-terminal Src kinase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSK mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:66,925,651...66,930,274
|
|
| G
|
Csmd1
|
CUB and Sushi multiple domains 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CSMD1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CSMD1 mRNA
|
CTD |
PMID:18164116 PMID:22129741 |
|
NCBI chr16:78,920,549...80,520,710
Ensembl chr16:78,921,002...80,519,944
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|
| G
|
Csn3
|
casein kappa
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CSN3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:20,433,277...20,439,830
Ensembl chr14:20,433,277...20,439,832
|
|
| G
|
Csnk2b
|
casein kinase 2 beta
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of CSNK2B mRNA; Diethylnitrosamine results in increased expression of CSNK2B protein 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CSNK2B mRNA]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CSNK2B protein]
|
CTD |
PMID:21554863 |
|
NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525
|
|
| G
|
Cspg4
|
chondroitin sulfate proteoglycan 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CSPG4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:66,160,942...66,200,806
|
|
| G
|
Csrp2
|
cysteine and glycine-rich protein 2
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CSRP2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238
|
|
| G
|
Csrp3
|
cysteine and glycine rich protein 3
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CSRP3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:107,664,338...107,682,916
|
|
| G
|
Cst6
|
cystatin E/M
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CST6 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:212,084,676...212,086,384
|
|
| G
|
Cstb
|
cystatin B
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CSTB mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,158...10,247,199
|
|
| G
|
Cth
|
cystathionine gamma-lyase
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CTH mRNA [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased expression of CTH mRNA
|
CTD |
PMID:28943392 PMID:29127188 |
|
NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066
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|
| G
|
Cthrc1
|
collagen triple helix repeat containing 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CTHRC1 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654
|
|
| G
|
Ctnnb1
|
catenin beta 1
|
multiple interactions increases expression affects localization increases mutagenesis decreases response to substance
|
ISO EXP
|
[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of and results in increased phosphorylation of CTNNB1 protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased mutagenesis of CTNNB1 gene; [Diethylnitrosamine promotes the reaction [TGFB1 protein affects the susceptibility to Dietary Fats]] which results in increased expression of CTNNB1 protein; [Phenobarbital co-treated with Diethylnitrosamine] results in increased mutagenesis of CTNNB1 gene; CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MYC protein]; CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PTGS2 protein]; CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of AKT1 protein]; CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of GSK3B protein]; CTNNB1 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of PDK1 protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of EGFR protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of HGF protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of HGFAC protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of MET protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CCND1 protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of FAS protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of NFKB1 protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of NFKBIA protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of RELA protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in increased expression of TRAF1 protein]; epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 mRNA]; epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 protein]; theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 mRNA]; theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 protein] Diethylnitrosamine results in increased expression of CTNNB1 mRNA; Diethylnitrosamine results in increased expression of CTNNB1 protein Diethylnitrosamine affects the localization of CTNNB1 protein modified form 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine affects the localization of CTNNB1 protein modified form]; 5,7-dimethoxyflavone inhibits the reaction [Diethylnitrosamine results in increased expression of CTNNB1 mRNA] Diethylnitrosamine results in increased mutagenesis of CTNNB1 CTNNB1 protein results in decreased susceptibility to Diethylnitrosamine
|
CTD |
PMID:10463579 PMID:20583210 PMID:21047994 PMID:21554863 PMID:24535843 PMID:27058323 PMID:30826251 More...
|
|
NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
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|
| G
|
Ctps2
|
CTP synthase 2
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CTPS2 mRNA Diethylnitrosamine results in increased expression of CTPS2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505
|
|
| G
|
Ctrc
|
chymotrypsin C
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CTRC mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:159,430,333...159,439,557
Ensembl chr 5:159,430,335...159,439,545
|
|
| G
|
Ctrl
|
chymotrypsin-like
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of CTRB1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr19:50,737,078...50,740,659
Ensembl chr19:50,737,079...50,738,979
|
|
| G
|
Ctsb
|
cathepsin B
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CTSB mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSB mRNA
|
CTD |
PMID:12771043 PMID:17602206 |
|
NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478
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| G
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Ctsc
|
cathepsin C
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of CTSC mRNA Diethylnitrosamine results in increased expression of CTSC mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CTSC mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CTSC mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CTSC mRNA; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CTSC mRNA]
|
CTD |
PMID:17602206 PMID:17942915 PMID:18164116 PMID:24535843 |
|
NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082
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|
| G
|
Ctse
|
cathepsin E
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of CTSE mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CTSE mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr13:45,644,168...45,666,722
Ensembl chr13:45,644,147...45,666,722
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|
| G
|
Ctsk
|
cathepsin K
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CTSK mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
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|
| G
|
Ctsl
|
cathepsin L
|
increases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CTSL mRNA
|
CTD |
PMID:12771043 PMID:20360939 |
|
NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113
|
|
| G
|
Ctsm
|
cathepsin M
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CTSM mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr17:3,242,488...3,247,896
Ensembl chr17:3,242,488...3,247,896
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|
| G
|
Ctsr
|
cathepsin R
|
multiple interactions increases expression
|
EXP
|
caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CTSR mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr17:3,527,990...3,536,753
Ensembl chr17:3,527,990...3,536,746
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|
| G
|
Ctss
|
cathepsin S
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of CTSS mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CTSS mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440
|
|
| G
|
Ctxn1
|
cortexin 1
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CTXN1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr12:7,408,308...7,409,919
Ensembl chr12:7,408,309...7,409,919
|
|
| G
|
Cul5
|
cullin 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CUL5 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463
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|
| G
|
Cuta
|
cutA divalent cation tolerance homolog
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CUTA mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr20:5,024,816...5,026,446
Ensembl chr20:5,024,816...5,026,631
|
|
| G
|
Cux2
|
cut-like homeobox 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CUX2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CUX2 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CUX2 mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528
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|
| G
|
Cx3cl1
|
C-X3-C motif chemokine ligand 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CX3CL1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CX3CL1 mRNA
|
CTD |
PMID:18164116 PMID:23830814 |
|
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
|
|
| G
|
Cxadr
|
CXADR, Ig-like cell adhesion molecule
|
increases expression
|
EXP ISO
|
Diethylnitrosamine results in increased expression of CXADR mRNA
|
CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988
|
|
| G
|
Cxcl10
|
C-X-C motif chemokine ligand 10
|
decreases expression multiple interactions increases expression
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of CXCL10 protein [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CXCL10 mRNA Diethylnitrosamine results in increased expression of CXCL10 protein
|
CTD |
PMID:24535843 PMID:25051504 |
|
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
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|
| G
|
Cxcl11
|
C-X-C motif chemokine ligand 11
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CXCL11 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567
|
|
| G
|
Cxcl12
|
C-X-C motif chemokine ligand 12
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CXCL12 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CXCL12 mRNA Diethylnitrosamine results in decreased expression of CXCL12 mRNA
|
CTD |
PMID:12771043 PMID:17602206 PMID:19041683 PMID:19638242 PMID:28943392 |
|
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
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|
| G
|
Cxcl14
|
C-X-C motif chemokine ligand 14
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CXCL14 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172
|
|
| G
|
Cxcl16
|
C-X-C motif chemokine ligand 16
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CXCL16 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226
|
|
| G
|
Cxcl17
|
C-X-C motif chemokine ligand 17
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CXCL17 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:90,112,561...90,124,648
Ensembl chr 1:90,112,771...90,124,535
|
|
| G
|
Cxcl3
|
C-X-C motif chemokine ligand 3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CXCL1 mRNA
|
CTD |
PMID:19919837 |
|
NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
|
|
| G
|
Cxcr3
|
C-X-C motif chemokine receptor 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CXCR3 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
|
|
| G
|
Cyb561
|
cytochrome b-561
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CYB561 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr10:91,377,866...91,388,548
Ensembl chr10:91,377,866...91,385,097
|
|
| G
|
Cyb5a
|
cytochrome b5 type A
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYB5A protein; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of CYB5A protein; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYB5A mRNA]; citral inhibits the reaction [Diethylnitrosamine results in increased expression of CYB5A protein] MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYB5A mRNA] CYB5A protein promotes the reaction [CYP2A6 protein results in increased activity of Diethylnitrosamine]; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of Diethylnitrosamine]
|
CTD |
PMID:15728263 PMID:17942915 PMID:19409407 PMID:20360939 PMID:20935162 PMID:32302048 More...
|
|
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094 Ensembl chr18:14,453,966...14,455,094
|
|
| G
|
Cyb5b
|
cytochrome b5 type B
|
multiple interactions
|
ISO
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine
|
CTD |
PMID:11733072 |
|
NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980
|
|
| G
|
Cyb5r3
|
cytochrome b5 reductase 3
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYB5R3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYB5R3 mRNA
|
CTD |
PMID:18544905 |
|
NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306
|
|
| G
|
Cyb5r4
|
cytochrome b5 reductase 4
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CYB5R4 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 8:96,860,415...96,925,789
Ensembl chr 8:96,861,090...96,926,094
|
|
| G
|
Cyba
|
cytochrome b-245 alpha chain
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with Dietary Fats co-treated with Canrenoic Acid] results in increased expression of CYBA mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CYBA mRNA; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of CYBA mRNA]
|
CTD |
PMID:20360939 PMID:28943392 PMID:30298849 |
|
NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
|
|
| G
|
Cycs
|
cytochrome c, somatic
|
multiple interactions decreases expression
|
EXP
|
morin inhibits the reaction [Diethylnitrosamine results in decreased expression of CYCS protein]
|
CTD |
PMID:19931519 |
|
NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816 Ensembl chr18:80,982,668...80,984,816
|
|
| G
|
Cyfip2
|
cytoplasmic FMR1 interacting protein 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYFIP2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440
|
|
| G
|
Cygb
|
cytoglobin
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYGB mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CYGB mRNA
|
CTD |
PMID:18164116 PMID:28943392 |
|
NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272
|
|
| G
|
Cyp11a1
|
cytochrome P450, family 11, subfamily a, polypeptide 1
|
decreases activity multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased activity of CYP11A1 protein [nodularin co-treated with Diethylnitrosamine] results in decreased activity of CYP11A1 protein
|
CTD |
PMID:12112309 |
|
NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
|
|
| G
|
Cyp17a1
|
cytochrome P450, family 17, subfamily a, polypeptide 1
|
multiple interactions increases expression decreases activity
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP17A1 mRNA; [nodularin co-treated with Diethylnitrosamine] results in decreased activity of CYP17A1 protein Diethylnitrosamine results in increased expression of CYP17A1 mRNA Diethylnitrosamine results in decreased activity of CYP17A1 protein
|
CTD |
PMID:12112309 PMID:17602206 PMID:24535843 |
|
NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974
|
|
| G
|
Cyp1a1
|
cytochrome P450, family 1, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
ISO EXP
|
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA] which results in increased abundance of Reactive Oxygen Species; [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; Diethylnitrosamine promotes the reaction [AHR protein binds to CYP1A1 promoter]; Plant Extracts inhibits the reaction [[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA] which results in increased abundance of Reactive Oxygen Species]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of CYP1A1 mRNA] Diethylnitrosamine results in increased expression of CYP1A1 mRNA; Diethylnitrosamine results in increased expression of CYP1A1 protein [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP1A1 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of CYP1A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 protein; allyl sulfide inhibits the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; Diethylnitrosamine results in increased expression of and results in increased activity of CYP1A1 protein; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA]
|
CTD |
PMID:11165752 PMID:15535986 PMID:17162532 PMID:18164116 PMID:18648771 PMID:18754104 PMID:18977376 PMID:19182440 PMID:19690152 PMID:20033131 PMID:20045035 PMID:20101389 PMID:20118626 PMID:21295105 PMID:22129741 PMID:22687989 PMID:23457121 PMID:23494807 PMID:23665939 PMID:27565560 More...
|
|
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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|
| G
|
Cyp1a2
|
cytochrome P450, family 1, subfamily a, polypeptide 2
|
multiple interactions decreases expression
|
ISO EXP
|
[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] which results in increased abundance of Reactive Oxygen Species; [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA Diethylnitrosamine results in decreased expression of CYP1A2 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP1A2 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP1A2 mRNA]; Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein
|
CTD |
PMID:18164116 PMID:18253720 PMID:18754104 PMID:19638242 PMID:20033131 PMID:20045035 PMID:20118626 PMID:20360939 PMID:22129741 PMID:22687989 PMID:23494807 PMID:24535843 PMID:27565560 PMID:28943392 More...
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|
NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
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|
| G
|
Cyp1b1
|
cytochrome P450, family 1, subfamily b, polypeptide 1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA] Diethylnitrosamine results in increased expression of CYP1B1 mRNA
|
CTD |
PMID:18164116 PMID:20045035 PMID:22129741 PMID:27565560 |
|
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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|
| G
|
Cyp21a1
|
cytochrome P450, family 21, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP21A1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr20:4,028,323...4,031,549
Ensembl chr20:4,028,391...4,031,543
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|
| G
|
Cyp26a1
|
cytochrome P450, family 26, subfamily a, polypeptide 1
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP26A1 mRNA Diethylnitrosamine results in decreased expression of CYP26A1 mRNA
|
CTD |
PMID:12771043 PMID:18164116 PMID:24535843 |
|
NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
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|
| G
|
Cyp26c1
|
cytochrome P450, family 26, subfamily C, polypeptide 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP26C1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:244,870,412...244,881,610
Ensembl chr 1:244,871,612...244,880,297
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|
| G
|
Cyp27a1
|
cytochrome P450, family 27, subfamily a, polypeptide 1
|
increases expression decreases expression
|
EXP ISO
|
Diethylnitrosamine results in increased expression of CYP27A1 mRNA Diethylnitrosamine results in decreased expression of CYP27A1 mRNA
|
CTD |
PMID:20360939 PMID:24535843 |
|
NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215
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|
| G
|
Cyp2a1
|
cytochrome P450, family 2, subfamily a, polypeptide 1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2A1 protein Diethylnitrosamine results in increased expression of CYP2A22 mRNA
|
CTD |
PMID:16246485 PMID:21607683 |
|
NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730
|
|
| G
|
Cyp2a2
|
cytochrome P450, family 2, subfamily a, polypeptide 2
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2A2 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2A2 mRNA Diethylnitrosamine results in decreased expression of CYP2A2 mRNA
|
CTD |
PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 1:91,391,492...91,417,158
Ensembl chr 1:91,391,502...91,417,158
|
|
| G
|
Cyp2a3
|
cytochrome P450, family 2, subfamily a, polypeptide 3
|
multiple interactions
|
EXP
|
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA
|
CTD |
PMID:18253720 |
|
NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649
|
|
| G
|
Cyp2b1
|
cytochrome P450, family 2, subfamily b, polypeptide 1
|
multiple interactions increases expression
|
EXP
|
[Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 protein; [DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP2B1 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2B1 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2B1 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2B1 protein; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2B1 mRNA; [Diethylnitrosamine co-treated with Clofibrate] results in increased expression of CYP2B1 protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2B1 protein; [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 protein; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [trimethylarsine oxide co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 mRNA; [trimethylarsine oxide co-treated with Diethylnitrosamine] results in increased expression of CYP2B1 protein Diethylnitrosamine results in increased expression of CYP2B1 mRNA
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CTD |
PMID:9744545 PMID:10550479 PMID:11165752 PMID:12115560 PMID:15885732 PMID:16246485 PMID:20360939 PMID:21763762 More...
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NCBI chr 1:90,646,098...90,669,762
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|
| G
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Cyp2b12
|
cytochrome P450, family 2, subfamily b, polypeptide 12
|
multiple interactions
|
EXP
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[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2B12 mRNA
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CTD |
PMID:22129741 |
|
NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159
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| G
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Cyp2b15
|
cytochrome P450, family 2, subfamily b, polypeptide 15
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2B15 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2B15 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2B15 mRNA Diethylnitrosamine results in decreased expression of CYP2B15 mRNA
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CTD |
PMID:18253720 PMID:18544905 PMID:19638242 |
|
NCBI chr 1:91,221,865...91,234,169
Ensembl chr 1:91,221,865...91,234,169
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| G
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Cyp2b2
|
cytochrome P450, family 2, subfamily b, polypeptide 2
|
multiple interactions increases expression
|
EXP ISO
|
[Cacodylic Acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP2B2 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [Diethylnitrosamine co-treated with Clofibrate] results in increased expression of CYP2B2 protein; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA; [ethofenprox co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [monomethylarsonic acid co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; [trimethylarsine oxide co-treated with Diethylnitrosamine] results in increased expression of CYP2B2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA]; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP2B2 mRNA] Diethylnitrosamine results in increased expression of CYP2B13 mRNA Diethylnitrosamine results in increased expression of CYP2B2 mRNA
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CTD |
PMID:10550479 PMID:12115560 PMID:15885732 PMID:18977376 PMID:20033131 PMID:21763762 PMID:22129741 PMID:22467020 PMID:24535843 More...
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|
NCBI chr 1:90,722,243...90,736,272
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|
| G
|
Cyp2b3
|
cytochrome P450, family 2, subfamily b, polypeptide 3
|
multiple interactions
|
ISO
|
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP2B10 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2B10 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP2B10 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of CYP2B10 mRNA; NR1I3 protein affects the reaction [[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2B10 mRNA]
|
CTD |
PMID:15492232 PMID:17917374 PMID:19690152 PMID:20101389 PMID:23457121 PMID:33398415 More...
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|
NCBI chr 1:90,780,468...90,859,852
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|
| G
|
Cyp2c11
|
cytochrome P450, subfamily 2, polypeptide 11
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP2C mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA Diethylnitrosamine results in decreased expression of CYP2C mRNA; Diethylnitrosamine results in decreased expression of CYP2C11 mRNA; Diethylnitrosamine results in decreased expression of CYP2C11 protein
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CTD |
PMID:14965361 PMID:16246485 PMID:17602206 PMID:18164116 PMID:18253720 PMID:18544905 PMID:19041683 PMID:19638242 PMID:20360939 PMID:28943392 PMID:29698782 More...
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|
NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853
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|
| G
|
Cyp2c12
|
cytochrome P450, family 2, subfamily c, polypeptide 12
|
decreases expression multiple interactions increases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2C12 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CYP2C40 mRNA Diethylnitrosamine results in increased expression of CYP2C40 mRNA
|
CTD |
PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 1:248,619,887...248,681,945
Ensembl chr 1:248,619,882...248,677,042
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|
| G
|
Cyp2c13
|
cytochrome P450, family 2, subfamily c, polypeptide 13
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C13 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C13 mRNA; caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2C13 mRNA]
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CTD |
PMID:11323195 PMID:18544905 PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210
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| G
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Cyp2c22
|
cytochrome P450, family 2, subfamily c, polypeptide 22
|
decreases expression multiple interactions
|
EXP
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Diethylnitrosamine results in decreased expression of CYP2C22 mRNA [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C70 mRNA
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CTD |
PMID:18544905 PMID:20360939 |
|
NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182
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|
| G
|
Cyp2c23
|
cytochrome P450, family 2, subfamily c, polypeptide 23
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP2C23 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP2C23 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C23 mRNA Diethylnitrosamine results in decreased expression of CYP2C23 mRNA
|
CTD |
PMID:11323195 PMID:17602206 PMID:18164116 PMID:28943392 |
|
NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067
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|
| G
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Cyp2c24
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cytochrome P450, family 2, subfamily c, polypeptide 24
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2C55 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CYP2C55 mRNA
|
CTD |
PMID:20360939 PMID:28943392 |
|
NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607
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|
| G
|
Cyp2c6
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cytochrome P450, family 2, subfamily C, polypeptide 6
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6 protein; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP2C6 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C6 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP2C6 mRNA Diethylnitrosamine results in decreased expression of CYP2C29 mRNA Diethylnitrosamine results in decreased expression of CYP2C6 mRNA
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CTD |
PMID:9744545 PMID:12771043 PMID:16246485 PMID:20360939 PMID:22129741 PMID:28943392 More...
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|
NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
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|
| G
|
Cyp2c7
|
cytochrome P450, family 2, subfamily c, polypeptide 7
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C7 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C7 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2C7 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C7 mRNA Diethylnitrosamine results in decreased expression of CYP2C7 mRNA
|
CTD |
PMID:18164116 PMID:18253720 PMID:18544905 PMID:19638242 PMID:28943392 |
|
NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:247,966,346...248,022,388
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|
| G
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Cyp2d2
|
cytochrome P450, family 2, subfamily d, polypeptide 2
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2D2 mRNA; Diethylnitrosamine results in decreased expression of CYP2D26 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2D26 mRNA
|
CTD |
PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281
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|
| G
|
Cyp2d3
|
cytochrome P450, family 2, subfamily d, polypeptide 3
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2D13 mRNA [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2D13 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2D13 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D13 mRNA
|
CTD |
PMID:18253720 PMID:18544905 PMID:19638242 PMID:28943392 |
|
NCBI chr 7:115,797,785...115,802,142
Ensembl chr 7:115,797,789...115,802,158
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|
| G
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Cyp2d4
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cytochrome P450, family 2, subfamily d, polypeptide 4
|
increases expression multiple interactions
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ISO EXP
|
Diethylnitrosamine results in increased expression of CYP2D22 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2D22 mRNA] [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2D22 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2D22 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA
|
CTD |
PMID:17942915 PMID:18253720 PMID:18544905 PMID:28943392 |
|
NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
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|
| G
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Cyp2d5
|
cytochrome P450, family 2, subfamily d, polypeptide 5
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2D10 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2D10 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 7:115,779,981...115,784,554
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|
| G
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Cyp2e1
|
cytochrome P450, family 2, subfamily e, polypeptide 1
|
multiple interactions increases expression decreases expression increases response to substance increases activity affects metabolic processing
|
ISO EXP
|
[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine; [CYP2E1 protein co-treated with POR protein] results in increased susceptibility to Diethylnitrosamine; CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of Diethylnitrosamine]; CYP2E1 protein affects the metabolism of and results in increased activity of Diethylnitrosamine Diethylnitrosamine results in increased expression of CYP2E1 protein Diethylnitrosamine results in increased expression of CYP2E1 mRNA; Diethylnitrosamine results in increased expression of CYP2E1 protein Diethylnitrosamine results in decreased expression of CYP2E1 mRNA; Diethylnitrosamine results in decreased expression of CYP2E1 protein CYP2E1 protein results in increased susceptibility to Diethylnitrosamine [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA; [Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2E1 mRNA; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein]; allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 mRNA]; Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein; neferine inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2E1 mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein]; thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 protein] CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA]; CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 mRNA]; Vitamin D inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2E1 protein] CYP2E1 protein affects the metabolism of Diethylnitrosamine
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CTD |
PMID:2655891 PMID:11035158 PMID:11733072 PMID:11774366 PMID:14656948 PMID:14669323 PMID:15728263 PMID:16158176 PMID:16246485 PMID:17393424 PMID:18056438 PMID:18544905 PMID:19551842 PMID:19638242 PMID:20360939 PMID:23494807 PMID:28943392 PMID:30423403 PMID:35437842 PMID:36442531 More...
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|
NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
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|
| G
|
Cyp2f4
|
cytochrome P450, family 2, subfamily f, polypeptide 4
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2F2 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA Diethylnitrosamine results in decreased expression of CYP2F2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CYP2F2 mRNA
|
CTD |
PMID:18253720 PMID:18544905 PMID:24535843 |
|
NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553
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|
| G
|
Cyp2g1
|
cytochrome P450, family 2, subfamily g, polypeptide 1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of CYP2G1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:91,273,309...91,284,499
Ensembl chr 1:91,272,680...91,284,498
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|
| G
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Cyp2j3
|
cytochrome P450, family 2, subfamily j, polypeptide 3
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP2J3 mRNA
|
CTD |
PMID:19041683 PMID:20360939 |
|
NCBI chr 5:116,335,755...116,360,677
Ensembl chr 5:116,335,755...116,360,499
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|
| G
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Cyp2u1
|
cytochrome P450, family 2, subfamily u, polypeptide 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2U1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 2:222,523,516...222,541,055
Ensembl chr 2:222,523,518...222,541,124
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|
| G
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Cyp39a1
|
cytochrome P450, family 39, subfamily a, polypeptide 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of CYP39A1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060
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|
| G
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Cyp3a18
|
cytochrome P450, family 3, subfamily a, polypeptide 18
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP3A18 mRNA caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP3A18 mRNA]
|
CTD |
PMID:19638242 PMID:20360939 |
|
NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788
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|
| G
|
Cyp3a2
|
cytochrome P450, family 3, subfamily a, polypeptide 2
|
multiple interactions decreases expression
|
EXP
|
[DDT co-treated with Diethylnitrosamine] results in decreased expression of CYP3A2 mRNA; [DDT co-treated with Diethylnitrosamine] results in increased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in decreased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP3A2 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP3A2 protein; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP3A11 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of CYP3A11 mRNA; Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP3A2 protein Diethylnitrosamine results in decreased expression of CYP3A11 mRNA
|
CTD |
PMID:9744545 PMID:11165752 PMID:15885732 PMID:16246485 PMID:18164116 PMID:18977376 PMID:19638242 PMID:28943392 PMID:29698782 More...
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|
NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
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|
| G
|
Cyp3a23-3a1
|
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
|
multiple interactions decreases expression
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP3A23-3A1 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP3A23-3A1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP3A23-3A1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of CYP3A23-3A1 mRNA; Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP3A23-3A1 protein Diethylnitrosamine results in decreased expression of CYP3A23-3A1 mRNA
|
CTD |
PMID:14656948 PMID:16158176 PMID:17602206 PMID:18253720 PMID:18977376 PMID:19638242 PMID:20360939 PMID:28943392 PMID:29698782 More...
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|
NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813
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|
| G
|
Cyp3a62
|
cytochrome P450, family 3, subfamily a, polypeptide 62
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP3A62 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CYP3A62 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP3A62 mRNA
|
CTD |
PMID:18164116 PMID:22129741 PMID:28943392 |
|
NCBI chr12:21,511,763...21,547,598
Ensembl chr12:21,471,542...21,547,598
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|
| G
|
Cyp3a9
|
cytochrome P450, family 3, subfamily a, polypeptide 9
|
increases expression multiple interactions decreases expression
|
ISO EXP
|
Diethylnitrosamine results in increased expression of CYP3A13 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A13 mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP3A13 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP3A13 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA Diethylnitrosamine results in decreased expression of CYP3A13 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP3A13 mRNA]
|
CTD |
PMID:17602206 PMID:17942915 PMID:18164116 PMID:18253720 PMID:19638242 PMID:28943392 More...
|
|
NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154
|
|
| G
|
Cyp46a1
|
cytochrome P450, family 46, subfamily a, polypeptide 1
|
multiple interactions decreases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CYP46A1 mRNA Diethylnitrosamine results in decreased expression of CYP46A1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971
|
|
| G
|
Cyp4a1
|
cytochrome P450, family 4, subfamily a, polypeptide 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibrate] results in increased expression of CYP4A1 protein; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4A22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP4A22 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP4A1 mRNA
|
CTD |
PMID:10550479 PMID:18544905 PMID:18775883 PMID:22129741 |
|
NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231
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|
| G
|
Cyp4a2
|
cytochrome P450, family 4, subfamily a, polypeptide 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP4A2 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 5:134,160,356...134,170,908
Ensembl chr 5:134,160,358...134,176,156
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|
| G
|
Cyp4a3
|
cytochrome P450, family 4, subfamily a, polypeptide 3
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP4A14 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP4A14 mRNA
|
CTD |
PMID:11323195 PMID:28943392 |
|
NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236
|
|
| G
|
Cyp4a8
|
cytochrome P450, family 4, subfamily a, polypeptide 8
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP4A8 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP4A8 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4A8 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP4A8 mRNA
|
CTD |
PMID:18164116 PMID:18253720 PMID:22129741 PMID:28943392 |
|
NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226
|
|
| G
|
Cyp4b1
|
cytochrome P450, family 4, subfamily b, polypeptide 1
|
multiple interactions
|
ISO EXP
|
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CYP4B1 mRNA [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA
|
CTD |
PMID:17917374 PMID:18253720 PMID:18544905 PMID:18977376 |
|
NCBI chr 5:134,375,807...134,413,635
Ensembl chr 5:134,375,807...134,393,116
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|
| G
|
Cyp4f1
|
cytochrome P450, family 4, subfamily f, polypeptide 1
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of CYP4F14 mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP4F2 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4F2 mRNA Diethylnitrosamine results in decreased expression of CYP4F2 mRNA
|
CTD |
PMID:12771043 PMID:17602206 PMID:18544905 PMID:19638242 PMID:24535843 |
|
NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612
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|
| G
|
Cyp4f17
|
cytochrome P450, family 4, subfamily f, polypeptide 17
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP4F17 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 7:12,169,366...12,186,731
Ensembl chr 7:12,169,922...12,187,540
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|
| G
|
Cyp4f4
|
cytochrome P450, family 4, subfamily f, polypeptide 4
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of CYP4F4 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP4F4 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 7:12,367,711...12,384,010
Ensembl chr 7:12,367,660...12,384,010
|
|
| G
|
Cyp4f5
|
cytochrome P450, family 4, subfamily f, polypeptide 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CYP4F5 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:12,194,567...12,209,495
Ensembl chr 7:12,195,022...12,209,965
|
|
| G
|
Cyp4f6
|
cytochrome P450, family 4, subfamily f, polypeptide 6
|
multiple interactions increases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP4F16 mRNA]
|
CTD |
PMID:17942915 PMID:24535843 |
|
NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402
|
|
| G
|
Cyp51
|
cytochrome P450, family 51
|
multiple interactions increases expression decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP51 mRNA Diethylnitrosamine results in increased expression of CYP51 mRNA Diethylnitrosamine results in decreased expression of CYP51 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:24535843 |
|
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450
|
|
| G
|
Cyp7a1
|
cytochrome P450 family 7 subfamily A member 1
|
multiple interactions decreases expression increases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP7A1 mRNA; IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP7A1 mRNA] Diethylnitrosamine results in decreased expression of CYP7A1 mRNA [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA
|
CTD |
PMID:14656948 PMID:16158176 PMID:17917374 PMID:18253720 PMID:18691550 PMID:19638242 PMID:24535843 More...
|
|
NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
|
|
| G
|
Cyp7b1
|
cytochrome P450 family 7 subfamily B member 1
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of CYP7B1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA
|
CTD |
PMID:12771043 PMID:18253720 |
|
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
|
|
| G
|
Cyp8b1
|
cytochrome P450 family 8 subfamily B member 1
|
multiple interactions decreases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP8B1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA Diethylnitrosamine results in decreased expression of CYP8B1 mRNA
|
CTD |
PMID:18253720 PMID:18544905 PMID:24535843 PMID:28943392 |
|
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689
|
|
| G
|
Cyth2
|
cytohesin 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of CYTH2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:105,419,631...105,427,542
Ensembl chr 1:105,419,631...105,427,542
|
|
| G
|
Dab1
|
DAB adaptor protein 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DAB1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584
|
|
| G
|
Dab2
|
DAB adaptor protein 2
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of DAB2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888
|
|
| G
|
Dach2
|
dachshund family transcription factor 2
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DACH2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr X:82,644,374...83,210,181
Ensembl chr X:82,644,128...83,210,000
|
|
| G
|
Dact2
|
dishevelled-binding antagonist of beta-catenin 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DACT2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:63,854,182...63,864,153
Ensembl chr 1:63,854,182...63,864,255
|
|
| G
|
Dad1
|
defender against cell death 1
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of DAD1 mRNA
|
CTD |
PMID:11323195 |
|
NCBI chr15:31,647,326...31,667,159
Ensembl chr15:31,647,326...31,667,287
|
|
| G
|
Dao
|
D-amino-acid oxidase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DAO mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300
|
|
| G
|
Dap
|
death-associated protein
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of DAP mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of DAP mRNA
|
CTD |
PMID:14656948 PMID:16158176 |
|
NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:83,910,060...83,962,673
|
|
| G
|
Dapk1
|
death associated protein kinase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of DAPK1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of DAPK1 promoter
|
CTD |
PMID:20970405 |
|
NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581
|
|
| G
|
Dapk2
|
death-associated protein kinase 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DAPK2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617
|
|
| G
|
Dbi
|
diazepam binding inhibitor
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DBI mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450
|
|
| G
|
Dbn1
|
drebrin 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBN1 mRNA; [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DBN1 mRNA
|
CTD |
PMID:18164116 PMID:20360939 |
|
NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122
|
|
| G
|
Dbp
|
D-box binding PAR bZIP transcription factor
|
decreases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of DBP mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBP mRNA MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DBP mRNA]
|
CTD |
PMID:17942915 PMID:18164116 PMID:19638242 |
|
NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205
|
|
| G
|
Dcaf4
|
DDB1 and CUL4 associated factor 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of WDR21 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:108,885,970...108,912,116
Ensembl chr 6:108,885,932...108,912,110
|
|
| G
|
Dcakd
|
dephospho-CoA kinase domain containing
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DCAKD mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of DCAKD mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of DCAKD promoter
|
CTD |
PMID:17602206 PMID:25374375 |
|
NCBI chr10:88,457,829...88,489,011
Ensembl chr10:88,457,829...88,480,118
|
|
| G
|
Dck
|
deoxycytidine kinase
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DCK mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DCK mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,589,298...19,610,326
|
|
| G
|
Dclk1
|
doublecortin-like kinase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DCLK1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090
|
|
| G
|
Dclk3
|
doublecortin-like kinase 3
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DCLK3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:120,279,916...120,332,362
Ensembl chr 8:120,279,757...120,332,432
|
|
| G
|
Dcn
|
decorin
|
increases expression multiple interactions decreases expression
|
EXP ISO
|
Diethylnitrosamine results in increased expression of DCN mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of DCN mRNA Diethylnitrosamine results in decreased expression of DCN mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DCN mRNA
|
CTD |
PMID:19638242 PMID:24535843 PMID:28943392 |
|
NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
|
|
| G
|
Dct
|
dopachrome tautomerase
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DCT mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DCT mRNA; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DCT mRNA]
|
CTD |
PMID:17942915 PMID:24535843 |
|
NCBI chr15:101,469,159...101,508,029
Ensembl chr15:101,469,159...101,508,029
|
|
| G
|
Dctpp1
|
dCTP pyrophosphatase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DCTPP1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:191,307,935...191,313,405
|
|
| G
|
Dcxr
|
dicarbonyl and L-xylulose reductase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of DCXR mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr10:106,504,730...106,506,619
|
|
| G
|
Ddb1
|
damage-specific DNA binding protein 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DDB1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596
|
|
| G
|
Ddc
|
dopa decarboxylase
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DDC mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
|
|
| G
|
Ddhd1
|
DDHD domain containing 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DDHD1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr15:21,304,053...21,370,608
Ensembl chr15:21,303,826...21,370,608
|
|
| G
|
Ddit3
|
DNA-damage inducible transcript 3
|
multiple interactions increases expression
|
ISO EXP
|
Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA] [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA
|
CTD |
PMID:18544905 PMID:18691550 |
|
NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
|
|
| G
|
Ddit4
|
DNA-damage-inducible transcript 4
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of DDIT4 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037
|
|
| G
|
Ddit4l
|
DNA-damage-inducible transcript 4-like
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of DDIT4L mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of DDIT4L mRNA
|
CTD |
PMID:19638242 PMID:21607683 PMID:24535843 PMID:28943392 |
|
NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225
|
|
| G
|
Ddr1
|
discoidin domain receptor tyrosine kinase 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DDR1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276
|
|
| G
|
Ddx21
|
DExD-box helicase 21
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DDX21 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238
|
|
| G
|
Ddx24
|
DEAD-box helicase 24
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DDX24 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625
|
|
| G
|
Ddx56
|
DEAD-box helicase 56
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DDX56 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262
|
|
| G
|
Deaf1
|
DEAF1 transcription factor
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DEAF1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:205,831,428...205,865,106
Ensembl chr 1:205,831,336...205,865,106
|
|
| G
|
Defb1
|
defensin beta 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of DEFB1 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of DEFB1 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068
|
|
| G
|
Defb105a
|
defensin beta 105A
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB12 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr16:76,838,686...76,841,113
Ensembl chr16:76,838,664...76,841,113
|
|
| G
|
Defb17
|
defensin beta 17
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DEFB41 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 9:28,376,792...28,380,421
Ensembl chr 9:28,376,792...28,380,421
|
|
| G
|
Defb18
|
defensin beta 18
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB18 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 9:28,348,776...28,349,793
Ensembl chr 9:28,348,776...28,349,793
|
|
| G
|
Defb49
|
defensin beta 49
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB49 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DEFB49 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DEFB49 mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr 9:28,329,236...28,333,898
Ensembl chr 9:28,329,236...28,333,999
|
|
| G
|
Degs1
|
delta(4)-desaturase, sphingolipid 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DEGS1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr13:96,478,645...96,485,302
Ensembl chr13:96,478,646...96,485,302
|
|
| G
|
Dek
|
DEK proto-oncogene
|
multiple interactions increases expression
|
ISO
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DEK mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122
|
|
| G
|
Dennd4a
|
DENN domain containing 4A
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DENND4A gene
|
CTD |
PMID:23968726 |
|
NCBI chr 8:74,218,131...74,331,543
Ensembl chr 8:74,218,191...74,331,542
|
|
| G
|
Derl3
|
derlin 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DERL3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477
|
|
| G
|
Dgkb
|
diacylglycerol kinase, beta
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DGKB mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:60,368,519...61,124,420
|
|
| G
|
Dgki
|
diacylglycerol kinase, iota
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of DGKI promoter; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of DGKI mRNA
|
CTD |
PMID:25374375 |
|
NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832
|
|
| G
|
Dguok
|
deoxyguanosine kinase
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DGUOK mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DGUOK mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 4:117,544,784...117,572,414
Ensembl chr 4:117,544,773...117,572,414
|
|
| G
|
Dhcr7
|
7-dehydrocholesterol reductase
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DHCR7 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382
|
|
| G
|
Dhfr
|
dihydrofolate reductase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DHFR mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 2:25,320,895...25,346,004
|
|
| G
|
Dhh
|
desert hedgehog signaling molecule
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DHH mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:131,929,857...131,935,352
|
|
| G
|
Dhodh
|
dihydroorotate dehydrogenase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DHODH mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr19:54,460,636...54,483,049
Ensembl chr19:54,468,690...54,514,496
|
|
| G
|
Dhrs2
|
dehydrogenase/reductase 2
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DHRS2 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588
|
|
| G
|
Dhrs3
|
dehydrogenase/reductase 3
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DHRS3 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653
|
|
| G
|
Dhrs7
|
dehydrogenase/reductase 7
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of DHRS7 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744
|
|
| G
|
Dhtkd1
|
dehydrogenase E1 and transketolase domain containing 1
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DHTKD1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071
|
|
| G
|
Diablo
|
diablo, IAP-binding mitochondrial protein
|
multiple interactions
|
EXP
|
[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of DIABLO mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DIABLO mRNA
|
CTD |
PMID:17602206 PMID:27048571 |
|
NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
|
|
| G
|
Diaph3
|
diaphanous-related formin 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DIAPH3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr15:68,951,992...69,421,623
Ensembl chr15:68,951,989...69,421,552
|
|
| G
|
Dio1
|
iodothyronine deiodinase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DIO1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771
|
|
| G
|
Dio2
|
iodothyronine deiodinase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DIO2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594
|
|
| G
|
Dipk1a
|
divergent protein kinase domain 1A
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DIPK1A mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:1,917,353...1,988,188
Ensembl chr14:1,917,324...1,988,678
|
|
| G
|
Disc1
|
DISC1 scaffold protein
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of DISC1 mRNA caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of DISC1 mRNA]
|
CTD |
PMID:20360939 |
|
NCBI chr19:69,911,548...70,120,970
Ensembl chr19:69,911,976...70,120,970
|
|
| G
|
Dkk4
|
dickkopf WNT signaling pathway inhibitor 4
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DKK4 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr16:76,105,679...76,109,044
Ensembl chr16:76,105,679...76,109,044
|
|
| G
|
Dmbt1
|
deleted in malignant brain tumors 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of DMBT1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DMBT1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of DMBT1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:28943392 |
|
NCBI chr 1:195,047,702...195,126,704
Ensembl chr 1:195,047,713...195,126,704
|
|
| G
|
Dmgdh
|
dimethylglycine dehydrogenase
|
decreases expression multiple interactions
|
EXP ISO
|
Diethylnitrosamine results in decreased expression of DMGDH mRNA [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DMGDH mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:24535843 |
|
NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071
|
|
| G
|
Dmrt1
|
doublesex and mab-3 related transcription factor 1
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DMRT1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DMRT1 mRNA [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of DMRT1 gene
|
CTD |
PMID:20360939 PMID:22129741 PMID:23968726 |
|
NCBI chr 1:232,569,179...232,667,646
Ensembl chr 1:232,569,072...232,668,370
|
|
| G
|
Dmrta1
|
DMRT-like family A1
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of DMRTA1 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DMRTA1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 5:109,531,704...109,538,244
Ensembl chr 5:109,531,586...109,538,246
|
|
| G
|
Dnaaf1
|
dynein, axonemal, assembly factor 1
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of DNAAF1 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of DNAAF1 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr19:64,532,859...64,560,942
Ensembl chr19:64,532,860...64,561,435
|
|
| G
|
Dnah10
|
dynein, axonemal, heavy chain 10
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH10 mRNA Diethylnitrosamine results in increased expression of DNAH10 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860
|
|
| G
|
Dnah3
|
dynein, axonemal, heavy chain 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DNAH3 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DNAH3 mRNA]
|
CTD |
PMID:22129741 |
|
NCBI chr 1:183,738,013...183,910,831
Ensembl chr 1:183,738,013...183,910,432
|
|
| G
|
Dnah5
|
dynein, axonemal, heavy chain 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DNAH5 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914
|
|
| G
|
Dnah9
|
dynein, axonemal, heavy chain 9
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DNAH9 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr10:50,996,796...51,363,977
Ensembl chr10:50,996,796...51,363,963
|
|
| G
|
Dnai1
|
dynein, axonemal, intermediate chain 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DNAI1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 5:61,526,079...61,596,806
Ensembl chr 5:61,525,999...61,596,810
|
|
| G
|
Dnaja1
|
DnaJ heat shock protein family (Hsp40) member A1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DNAJA1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA1 mRNA
|
CTD |
PMID:17602206 PMID:18544905 |
|
NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160
|
|
| G
|
Dnaja2
|
DnaJ heat shock protein family (Hsp40) member A2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DNAJA2 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA
|
CTD |
PMID:18253720 PMID:18544905 |
|
NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120
|
|
| G
|
Dnajb1
|
DnaJ heat shock protein family (Hsp40) member B1
|
multiple interactions decreases expression
|
ISO EXP
|
IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNAJB1 mRNA] [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA
|
CTD |
PMID:18253720 PMID:18691550 |
|
NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416
|
|
| G
|
Dnajc9
|
DnaJ heat shock protein family (Hsp40) member C9
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DNAJC9 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNAJC9 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304
|
|
| G
|
Dnase2
|
deoxyribonuclease 2, lysosomal
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DNASE2A mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr19:40,149,505...40,152,225
Ensembl chr19:40,149,505...40,152,225
|
|
| G
|
Dnm1
|
dynamin 1
|
multiple interactions increases expression
|
ISO EXP
|
RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNM1 mRNA] [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1 mRNA
|
CTD |
PMID:17854601 PMID:18164116 |
|
NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:36,002,064...36,046,289
|
|
| G
|
Dnm1l
|
dynamin 1-like
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1L mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420
|
|
| G
|
Dnmt1
|
DNA methyltransferase 1
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNMT1 mRNA]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNMT1 mRNA] [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein
|
CTD |
PMID:17854601 PMID:19996281 PMID:21163286 |
|
NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
|
|
| G
|
Dnmt3a
|
DNA methyltransferase 3 alpha
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT3A protein
|
CTD |
PMID:21163286 |
|
NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
|
|
| G
|
Dnph1
|
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DNPH1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631
|
|
| G
|
Dntt
|
DNA nucleotidylexotransferase
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DNTT mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:249,805,802...249,837,685
Ensembl chr 1:249,805,802...249,837,684
|
|
| G
|
Dock3
|
dedicator of cyto-kinesis 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DOCK3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 8:116,431,158...116,782,218
Ensembl chr 8:116,431,159...116,782,195
|
|
| G
|
Dock8
|
dedicator of cytokinesis 8
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of DOCK8 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833
|
|
| G
|
Dock9
|
dedicator of cytokinesis 9
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DOCK9 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799
|
|
| G
|
Dok1
|
docking protein 1
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DOK1 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DOK1 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 4:117,095,171...117,098,251
Ensembl chr 4:117,095,175...117,097,825
|
|
| G
|
Dpep1
|
dipeptidase 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPEP1 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775
|
|
| G
|
Dpp4
|
dipeptidylpeptidase 4
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPP4 mRNA Diethylnitrosamine results in increased expression of DPP4 protein Vitamin D inhibits the reaction [Diethylnitrosamine results in increased expression of DPP4 protein]
|
CTD |
PMID:17602206 PMID:36442531 |
|
NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
|
|
| G
|
Dpp7
|
dipeptidylpeptidase 7
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPP7 mRNA Diethylnitrosamine results in increased expression of DPP7 mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 3:28,563,240...28,567,492
Ensembl chr 3:28,563,240...28,567,492
|
|
| G
|
Dpt
|
dermatopontin
|
multiple interactions
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPT mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DPT mRNA
|
CTD |
PMID:17602206 PMID:24535843 |
|
NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758
|
|
| G
|
Dpy19l3
|
dpy-19 like C-mannosyltransferase 3
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DPY19L3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 1:97,487,206...97,554,232
Ensembl chr 1:97,487,206...97,554,232
|
|
| G
|
Dpy30
|
dpy-30 histone methyltransferase complex regulatory subunit
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPY30 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930
|
|
| G
|
Dpyd
|
dihydropyrimidine dehydrogenase
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPYD mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DPYD mRNA Diethylnitrosamine results in decreased expression of DPYD mRNA
|
CTD |
PMID:17602206 PMID:18544905 PMID:19638242 |
|
NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778
|
|
| G
|
Dpys
|
dihydropyrimidinase
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of DPYS mRNA; [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPYS mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of DPYS mRNA Diethylnitrosamine results in decreased expression of DPYS mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:20360939 PMID:28943392 |
|
NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142
|
|
| G
|
Dpysl2
|
dihydropyrimidinase-like 2
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of DPYSL2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065
|
|
| G
|
Drc1
|
dynein regulatory complex subunit 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DRC1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 6:31,744,849...31,779,996
Ensembl chr 6:31,744,850...31,779,256
|
|
| G
|
Dsg1
|
desmoglein 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DSG1B mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DSG1B mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr18:11,948,098...11,980,455
Ensembl chr18:11,949,488...11,980,451
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|
| G
|
Dtnb
|
dystrobrevin, beta
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DTNB mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 6:32,286,022...32,483,007
Ensembl chr 6:32,285,941...32,485,872
|
|
| G
|
Dtymk
|
deoxythymidylate kinase
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of DTYMK mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DTYMK mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504
|
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| G
|
Dusp1
|
dual specificity phosphatase 1
|
multiple interactions increases expression
|
ISO EXP
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DUSP1 mRNA] [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of DUSP1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DUSP1 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of DUSP1 promoter
|
CTD |
PMID:15833021 PMID:17942915 PMID:25374375 |
|
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
|
|
| G
|
Dusp13b
|
dual specificity phosphatase 13B
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DUSP13B mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DUSP13B mRNA
|
CTD |
PMID:18164116 PMID:22129741 |
|
NCBI chr15:2,616,761...2,624,434
Ensembl chr15:2,609,049...2,624,887
|
|
| G
|
Dusp3
|
dual specificity phosphatase 3
|
multiple interactions decreases expression
|
EXP
|
[Sorafenib co-treated with Methionine] inhibits the reaction [Diethylnitrosamine results in decreased expression of DUSP3 mRNA]
|
CTD |
PMID:38367245 |
|
NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063
|
|
| G
|
Dusp4
|
dual specificity phosphatase 4
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of DUSP4 mRNA IKBKB protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DUSP4 mRNA]; MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DUSP4 mRNA]
|
CTD |
PMID:18691550 |
|
NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700
|
|
| G
|
Dusp5
|
dual specificity phosphatase 5
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of DUSP5 mRNA
|
CTD |
PMID:21527772 PMID:24535843 |
|
NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417
|
|
| G
|
Dusp6
|
dual specificity phosphatase 6
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in increased expression of DUSP6 mRNA Diethylnitrosamine results in increased expression of DUSP6 mRNA
|
CTD |
PMID:20360939 PMID:24535843 |
|
NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833
|
|
| G
|
Dvl1
|
dishevelled segment polarity protein 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DVL1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 5:171,738,911...171,750,967
Ensembl chr 5:171,739,133...171,750,966
|
|
| G
|
Dxo
|
decapping exoribonuclease
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DXO mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr20:3,997,953...4,000,115
Ensembl chr20:3,997,955...4,000,037
|
|
| G
|
Dync1li2
|
dynein, cytoplasmic 1 light intermediate chain 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DYNC1LI2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr19:538,207...561,110
Ensembl chr19:538,211...561,107
|
|
| G
|
Dynll1
|
dynein light chain LC8-type 1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DYNLL1 mRNA Diethylnitrosamine results in increased expression of DYNLL1 mRNA
|
CTD |
PMID:17602206 PMID:19041683 PMID:24535843 |
|
NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861
|
|
| G
|
Dynll2
|
dynein light chain LC8-type 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DYNLL2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285
|
|
| G
|
Dynlt1
|
dynein light chain Tctex-type 1
|
multiple interactions increases expression
|
ISO
|
MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DYNLT1 mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:49,282,243...49,298,951
|
|
| G
|
Dyrk3
|
dual specificity tyrosine phosphorylation regulated kinase 3
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of DYRK3 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr13:45,146,383...45,157,082
Ensembl chr13:45,146,384...45,157,249
|
|
| G
|
Dzip1l
|
DAZ interacting zinc finger protein 1-like
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DZIP1L mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 8:109,067,466...109,108,390
Ensembl chr 8:109,067,775...109,108,393
|
|
| G
|
E2f1
|
E2F transcription factor 1
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of E2F1 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of E2F1 mRNA]; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of E2F1 protein] Diethylnitrosamine results in increased expression of E2F1 mRNA; Diethylnitrosamine results in increased expression of E2F1 protein
|
CTD |
PMID:17854601 PMID:19887370 PMID:20101389 |
|
NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563
|
|
| G
|
E2f6
|
E2F transcription factor 6
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of E2F6 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 6:45,320,993...45,337,437
Ensembl chr 6:45,320,996...45,337,428
|
|
| G
|
Ebna1bp2
|
EBNA1 binding protein 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EBNA1BP2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637
|
|
| G
|
Ebp
|
EBP, cholestenol delta-isomerase
|
decreases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in decreased expression of EBP mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EBP mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781
|
|
| G
|
Ebpl
|
EBP like
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of EBPL mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of EBPL promoter
|
CTD |
PMID:25374375 |
|
NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537
|
|
| G
|
Echdc2
|
enoyl CoA hydratase domain containing 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ECHDC2 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of ECHDC2 promoter
|
CTD |
PMID:25374375 |
|
NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610
|
|
| G
|
Echs1
|
enoyl-CoA hydratase, short chain 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ECHS1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
|
|
| G
|
Ecm1
|
extracellular matrix protein 1
|
decreases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in decreased expression of ECM1 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ECM1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606
|
|
| G
|
Ect2
|
epithelial cell transforming 2
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of ECT2 mRNA [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ECT2 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ECT2 mRNA]
|
CTD |
PMID:17854601 PMID:24535843 |
|
NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626
|
|
| G
|
Eda2r
|
ectodysplasin A2 receptor
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of EDA2R mRNA
|
CTD |
PMID:21607683 |
|
NCBI chr X:66,225,557...66,280,674
Ensembl chr X:66,236,111...66,280,663
|
|
| G
|
Edn1
|
endothelin 1
|
multiple interactions increases expression
|
EXP
|
[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein; Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein]; Dahuang Zhechong pill inhibits the reaction [Diethylnitrosamine results in increased expression of EDN1 protein]
|
CTD |
PMID:20302851 PMID:36731809 |
|
NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
|
|
| G
|
Ednrb
|
endothelin receptor type B
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of EDNRB mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765
|
|
| G
|
Eef1e1
|
eukaryotic translation elongation factor 1 epsilon 1
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EEF1E1 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687
|
|
| G
|
Eeig2
|
EEIG family member 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of EEIG2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 2:199,296,582...199,351,449
Ensembl chr 2:199,296,582...199,351,449
|
|
| G
|
Efcab3
|
EF-hand calcium binding domain 3
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFCAB3 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:90,084,495...90,577,145
Ensembl chr10:90,084,397...90,577,144
|
|
| G
|
Efemp1
|
EGF containing fibulin extracellular matrix protein 1
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of EFEMP1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
|
|
| G
|
Efemp2
|
EGF containing fibulin extracellular matrix protein 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EFEMP2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739
|
|
| G
|
Efna1
|
ephrin A1
|
multiple interactions increases expression
|
ISO EXP
|
MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EFNA1 mRNA] [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFNA1 mRNA
|
CTD |
PMID:18691550 PMID:22129741 |
|
NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726
|
|
| G
|
Efna3
|
ephrin A3
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EFNA3 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 2:177,026,928...177,035,838
Ensembl chr 2:177,026,933...177,044,843
|
|
| G
|
Egf
|
epidermal growth factor
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of EGF mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
|
|
| G
|
Egflam
|
EGF-like, fibronectin type III and laminin G domains
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of EGFLAM mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 2:58,029,934...58,204,010
Ensembl chr 2:58,029,935...58,203,643
|
|
| G
|
Egfr
|
epidermal growth factor receptor
|
multiple interactions increases expression decreases expression
|
ISO EXP
|
[Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA; Acetylcysteine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of EGFR protein]; Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein; epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] Diethylnitrosamine results in decreased expression of EGFR mRNA; Diethylnitrosamine results in decreased expression of EGFR protein [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein; [Diethylnitrosamine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR protein; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EGFR mRNA; Curcumin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein]; turmeric extract inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA]
|
CTD |
PMID:8403215 PMID:15660382 PMID:17942915 PMID:19638242 PMID:20101389 PMID:20583210 PMID:27058323 PMID:28943392 PMID:29923357 PMID:37858842 More...
|
|
NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
|
|
| G
|
Egln3
|
egl-9 family hypoxia-inducible factor 3
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EGLN3 mRNA Diethylnitrosamine results in increased expression of EGLN3 mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015
|
|
| G
|
Egr1
|
early growth response 1
|
increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in increased expression of EGR1 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EGR1 mRNA] [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EGR1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of EGR1 mRNA
|
CTD |
PMID:17854601 PMID:18164116 PMID:18544905 PMID:19638242 PMID:21527772 PMID:24535843 More...
|
|
NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843
|
|
| G
|
Ehd2
|
EH-domain containing 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD2 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943
|
|
| G
|
Ehd4
|
EH-domain containing 4
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD4 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072
|
|
| G
|
Ehhadh
|
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
|
multiple interactions decreases expression
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EHHADH mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EHHADH mRNA Diethylnitrosamine results in decreased expression of EHHADH mRNA
|
CTD |
PMID:17602206 PMID:19638242 PMID:28943392 |
|
NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
|
|
| G
|
Ei24
|
EI24, autophagy associated transmembrane protein
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of EI24 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EI24 mRNA]
|
CTD |
PMID:17854601 |
|
NCBI chr 8:44,683,138...44,699,502
Ensembl chr 8:44,683,144...44,695,214
|
|
| G
|
Eif2s2
|
eukaryotic translation initiation factor 2 subunit beta
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF2S2 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570
|
|
| G
|
Eif3b
|
eukaryotic translation initiation factor 3, subunit B
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3B mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939
|
|
| G
|
Eif3c
|
eukaryotic translation initiation factor 3, subunit C
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3C mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067
|
|
| G
|
Eif3g
|
eukaryotic translation initiation factor 3, subunit G
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3G mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 8:27,705,914...27,709,946
Ensembl chr 8:27,705,915...27,709,987
|
|
| G
|
Eif3h
|
eukaryotic translation initiation factor 3, subunit H
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3H mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:84,980,891...85,064,284
Ensembl chr 7:84,980,891...85,071,546
|
|
| G
|
Eif3k
|
eukaryotic translation initiation factor 3, subunit K
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3K mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 1:93,387,628...93,397,551
Ensembl chr 1:93,387,628...93,397,802
|
|
| G
|
Eif3l
|
eukaryotic translation initiation factor 3, subunit L
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF3L mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 7:112,522,222...112,544,063
Ensembl chr 7:112,507,831...112,544,062
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| G
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Eif5a
|
eukaryotic translation initiation factor 5A
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EIF5A mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330
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| G
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Elac2
|
elaC ribonuclease Z 2
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ELAC2 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069
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| G
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Elavl1
|
ELAV like RNA binding protein 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ELAVL1 protein
|
CTD |
PMID:37021545 |
|
NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631
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| G
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Elf1
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E74 like ETS transcription factor 1
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ELF1 mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr15:61,354,026...61,395,762
Ensembl chr15:61,330,877...61,395,758
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| G
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Ell
|
elongation factor for RNA polymerase II
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ELL mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of ELL promoter
|
CTD |
PMID:25374375 |
|
NCBI chr16:18,877,751...18,925,449
Ensembl chr16:18,877,751...18,925,076
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| G
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Eln
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elastin
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ELN mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413
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| G
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Elob
|
elongin B
|
increases expression multiple interactions
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ISO
|
Diethylnitrosamine results in increased expression of ELOB mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ELOB mRNA]
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CTD |
PMID:17942915 |
|
NCBI chr10:13,353,413...13,358,484
Ensembl chr10:13,353,417...13,358,563
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| G
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Elovl3
|
ELOVL fatty acid elongase 3
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ELOVL3 mRNA
|
CTD |
PMID:12771043 PMID:24535843 |
|
NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:254,938,731...254,942,559
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| G
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Elovl7
|
ELOVL fatty acid elongase 7
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ELOVL7 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:41,522,738...41,592,020
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| G
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Emcn
|
endomucin
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of EMCN mRNA Diethylnitrosamine results in increased expression of EMCN mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 2:228,564,445...228,644,370
Ensembl chr 2:228,564,430...228,645,155
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| G
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Emilin2
|
elastin microfibril interfacer 2
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EMILIN2 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 9:118,607,312...118,667,087
Ensembl chr 9:118,606,891...118,666,957
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| G
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Emp1
|
epithelial membrane protein 1
|
decreases expression increases expression multiple interactions
|
ISO EXP
|
Diethylnitrosamine results in decreased expression of EMP1 mRNA Diethylnitrosamine results in increased expression of EMP1 mRNA [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EMP1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:21527772 |
|
NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365
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| G
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Emp2
|
epithelial membrane protein 2
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of EMP2 mRNA
|
CTD |
PMID:21607683 |
|
NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532
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| G
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Enc1
|
ectodermal-neural cortex 1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENC1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ENC1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ENC1 mRNA Diethylnitrosamine results in increased expression of ENC1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 PMID:21607683 PMID:22129741 PMID:24535843 PMID:28943392 More...
|
|
NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721
|
|
| G
|
Endod1
|
endonuclease domain containing 1
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ENDOD1 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr 8:19,490,615...19,520,007
Ensembl chr 8:19,490,615...19,520,007
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|
| G
|
Eng
|
endoglin
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ENG mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933
|
|
| G
|
Eno1
|
enolase 1
|
multiple interactions
|
EXP
|
[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of ENO1 mRNA; [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of ENO1 mRNA
|
CTD |
PMID:14656948 PMID:16158176 |
|
NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003 Ensembl chr 5:77,946,261...77,986,003
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|
| G
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Enpep
|
glutamyl aminopeptidase
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ENPEP mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218
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| G
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Enpp1
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ectonucleotide pyrophosphatase/phosphodiesterase 1
|
increases expression
|
EXP ISO
|
Diethylnitrosamine results in increased expression of ENPP1 mRNA
|
CTD |
PMID:19638242 PMID:24535843 |
|
NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044
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| G
|
Enpp2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
decreases expression
|
EXP
|
Diethylnitrosamine results in decreased expression of ENPP2 mRNA
|
CTD |
PMID:19638242 |
|
NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
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|
| G
|
Enpp5
|
ectonucleotide pyrophosphatase/phosphodiesterase family member 5
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENPP5 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 9:24,407,574...24,415,029
Ensembl chr 9:24,408,218...24,414,867
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|
| G
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Enpp7
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ectonucleotide pyrophosphatase/phosphodiesterase 7
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENPP7 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,740,763...104,745,760
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|
| G
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Entpd2
|
ectonucleoside triphosphate diphosphohydrolase 2
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENTPD2 mRNA Diethylnitrosamine results in increased expression of ENTPD2 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:28,611,772...28,618,184
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|
| G
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Entpd5
|
ectonucleoside triphosphate diphosphohydrolase 5
|
increases expression multiple interactions
|
EXP
|
Diethylnitrosamine results in increased expression of ENTPD5 mRNA [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of ENTPD5 mRNA
|
CTD |
PMID:19638242 PMID:28943392 |
|
NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495
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|
| G
|
Entrep1
|
endosomal transmembrane epsin interactor 1
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENTREP1 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 1:231,018,987...231,073,474
Ensembl chr 1:231,018,987...231,102,708
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|
| G
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Epb41
|
erythrocyte membrane protein band 4.1
|
multiple interactions
|
ISO
|
[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EPB41 gene
|
CTD |
PMID:23968726 |
|
NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540
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|
| G
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Epb41l3
|
erythrocyte membrane protein band 4.1-like 3
|
affects expression
|
EXP
|
Diethylnitrosamine affects the expression of EPB41L3 mRNA
|
CTD |
PMID:17428255 |
|
NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274
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|
| G
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Epcam
|
epithelial cell adhesion molecule
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPCAM mRNA Diethylnitrosamine results in increased expression of EPCAM mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702
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|
| G
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Epdr1
|
ependymin related 1
|
multiple interactions increases expression
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPDR1 mRNA Diethylnitrosamine results in increased expression of EPDR1 mRNA
|
CTD |
PMID:18164116 PMID:19638242 |
|
NCBI chr17:50,029,591...50,054,254
Ensembl chr17:50,029,256...50,054,250
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|
| G
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Epha8
|
Eph receptor A8
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EPHA8 mRNA
|
CTD |
PMID:28943392 |
|
NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966
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|
| G
|
Ephb1
|
Eph receptor B1
|
multiple interactions increases phosphorylation
|
EXP ISO
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPHB1 mRNA N-nitrosodiethylamine increases phosphorylation of Ephb1 protein in liver
|
CTD RGD |
PMID:22129741 PMID:28100771 |
RGD:127285675 |
NCBI chr 8:111,386,432...111,823,759
Ensembl chr 8:111,386,432...111,823,759
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|
| G
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Ephb4
|
EPH receptor B4
|
multiple interactions
|
EXP
|
1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of EPHB4 protein]; [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of EPHB4 protein
|
CTD |
PMID:28693887 |
|
NCBI chr12:24,963,174...24,988,473
Ensembl chr12:24,963,174...24,988,388
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|
| G
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Ephx1
|
epoxide hydrolase 1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of EPHX1 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 protein Diethylnitrosamine results in increased expression of EPHX1 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA]
|
CTD |
PMID:17602206 PMID:17854601 PMID:18544905 PMID:19638242 PMID:20360939 PMID:20935162 PMID:21607683 PMID:28943392 More...
|
|
NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981
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|
| G
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Ephx2
|
epoxide hydrolase 2
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX2 mRNA
|
CTD |
PMID:18544905 |
|
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
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|
| G
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Epor
|
erythropoietin receptor
|
increases expression multiple interactions
|
ISO
|
Diethylnitrosamine results in increased expression of EPOR mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPOR mRNA]
|
CTD |
PMID:17942915 |
|
NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322
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|
| G
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Eps15
|
epidermal growth factor receptor pathway substrate 15
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EPS15 mRNA
|
CTD |
PMID:18164116 |
|
NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856
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|
| G
|
Eps8
|
EGFR pathway substrate 8, signaling adaptor
|
multiple interactions
|
EXP
|
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPS8 mRNA
|
CTD |
PMID:22129741 |
|
NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160
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|
| G
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Erc1
|
ELKS/RAB6-interacting/CAST family member 1
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ERC1 mRNA
|
CTD |
PMID:20360939 |
|
NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987
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|
| G
|
Ercc2
|
ERCC excision repair 2, TFIIH core complex helicase subunit
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102
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|
| G
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Ercc3
|
ERCC excision repair 3, TFIIH core complex helicase subunit
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ERCC3 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of ERCC3 mRNA
|
CTD |
PMID:17602206 PMID:18544905 |
|
NCBI chr18:24,157,831...24,188,543
Ensembl chr18:24,148,084...24,190,898
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|
| G
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Ercc4
|
ERCC excision repair 4, endonuclease catalytic subunit
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA
|
CTD |
PMID:17917374 |
|
NCBI chr10:2,926,085...2,958,176
Ensembl chr10:2,920,455...2,955,539
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|
| G
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Ercc5
|
ERCC excision repair 5, endonuclease
|
multiple interactions increases expression
|
ISO
|
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA; RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ERCC5 mRNA]
|
CTD |
PMID:17854601 PMID:17917374 |
|
NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084
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|
| G
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Ercc6l
|
ERCC excision repair 6 like, spindle assembly checkpoint helicase
|
increases expression
|
EXP
|
Diethylnitrosamine results in increased expression of ERCC6L mRNA
|
CTD |
PMID:19041683 |
|
NCBI chr X:71,285,380...71,301,186
Ensembl chr X:71,285,380...71,301,186
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|
| G
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Ero1b
|
endoplasmic reticulum oxidoreductase 1 beta
|
increases expression
|
ISO
|
Diethylnitrosamine results in increased expression of ERO1B mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr17:92,913,696...92,987,401
Ensembl chr17:92,814,368...92,987,555
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|
| G
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Erp27
|
endoplasmic reticulum protein 27
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ERP27 mRNA
|
CTD |
PMID:21527772 PMID:24535843 |
|
NCBI chr 4:171,535,845...171,552,848
Ensembl chr 4:171,535,847...171,553,072
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|
| G
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Erp29
|
endoplasmic reticulum protein 29
|
multiple interactions
|
EXP
|
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ERP29 mRNA
|
CTD |
PMID:17602206 |
|
NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
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|
| G
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Esco2
|
establishment of sister chromatid cohesion N-acetyltransferase 2
|
multiple interactions
|
ISO
|
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of ESCO2 mRNA
|
CTD |
PMID:24535843 |
|
NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304 Ensembl chr15:44,210,641...44,231,304
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|
| G
|
Esm1
|
endothelial cell-specific molecule 1
|
multiple interactions increases expression
|
EXP ISO
|
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ESM1 mRNA Diethylnitrosamine results in increased expression of ESM1 mRNA
|
CTD |
PMID:18164116 PMID:24535843 |
|
NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:46,609,204...46,617,990
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|
| G
|
Espn
|
espin
|
decreases expression
|
ISO
|
Diethylnitrosamine results in decreased expression of ESPN mRNA
|
CTD |
PMID:21527772 |
|
NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984
|
|
| G
|
Esr1
|
estrogen receptor 1
|
multiple interactions increases expression
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA]; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [[Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein]; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA; [bisphenol A co-treated with Diethylnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR1 protein; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 mRNA; [Diethylnitrosamine co-treated with Methylnitrosourea co-treated with diisopropanolnitrosamine] results in increased expression of ESR1 protein Diethylnitrosamine results in increased expression of ESR1 protein
|
CTD |
PMID:34186418 PMID:36608567 |
|
NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
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|
| G
|
Esr2
|
estrogen receptor 2
|
multiple interactions increases expression
|
EXP
|
[bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [Diethylnitrosamine results in increased expression of ESR2 mRNA]; [bisphenol A co-treated with Diethylhexyl Phthalate] promotes the reaction [Diethylnitrosamine results in increased expression of ESR2 protein]; [bisphenol A co-treated with Diethylnitrosamine] results in increased expression of ESR2 protein; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR2 mRNA; [Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR2 protein; bisphenol A promotes the reaction [[Diethylhexyl Phthalate co-treated with Diethylnitrosamine] results in increased expression of ESR2 protein]; bisphenol A promotes the reaction [Diethylnitrosamine results in increased expression of ESR2 mRNA]
|
CTD |
PMID:36608567 |
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NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
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| G
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Etfbkmt
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electron transfer flavoprotein subunit beta lysine methyltransferase
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decreases expression
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ISO
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Diethylnitrosamine results in decreased expression of ETFBKMT mRNA
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CTD |
PMID:24535843 |
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NCBI chr 4:183,871,819...183,936,843
Ensembl chr 4:183,871,827...183,881,621
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| G
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Ethe1
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ETHE1, persulfide dioxygenase
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ETHE1 mRNA
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CTD |
PMID:28943392 |
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NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998
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| G
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Etnk1
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ethanolamine kinase 1
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ETNK1 mRNA
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CTD |
PMID:17602206 |
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NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721
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| G
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Etnppl
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ethanolamine-phosphate phospho-lyase
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decreases expression
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ISO
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Diethylnitrosamine results in decreased expression of ETNPPL mRNA
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CTD |
PMID:24535843 |
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NCBI chr 2:221,847,210...221,868,827
Ensembl chr 2:221,847,250...221,866,357
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| G
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Ets1
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ETS proto-oncogene 1, transcription factor
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of ETS1 mRNA
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CTD |
PMID:20360939 |
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NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021
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| G
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Ets2
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ETS proto-oncogene 2, transcription factor
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of ETS2 mRNA
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CTD |
PMID:12771043 |
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NCBI chr11:48,491,057...48,507,843
Ensembl chr11:48,491,394...48,507,842
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| G
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Etv4
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ETS variant transcription factor 4
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of ETV4 mRNA RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of ETV4 mRNA]
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CTD |
PMID:17854601 |
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NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318
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| G
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Etv5
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ETS variant transcription factor 5
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of ETV5 mRNA
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CTD |
PMID:24535843 |
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NCBI chr11:92,113,171...92,170,758
Ensembl chr11:92,113,224...92,170,767
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| G
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Exoc2
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exocyst complex component 2
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multiple interactions
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ISO
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[Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of EXOC2 gene
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CTD |
PMID:23968726 |
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NCBI chr17:33,714,949...33,906,901
Ensembl chr17:33,715,008...33,901,944
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| G
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Exoc4
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exocyst complex component 4
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increases expression
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ISO
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Diethylnitrosamine results in increased expression of EXOC4 mRNA
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CTD |
PMID:21607683 |
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NCBI chr 4:62,774,896...63,551,541
Ensembl chr 4:62,774,935...63,552,943
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| G
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Exoc8
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exocyst complex component 8
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increases expression multiple interactions
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ISO
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Diethylnitrosamine results in increased expression of EXOC8 mRNA MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EXOC8 mRNA]
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CTD |
PMID:17942915 |
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NCBI chr19:69,752,387...69,754,876
Ensembl chr19:69,727,231...69,804,820
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| G
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Exosc5
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exosome component 5
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multiple interactions
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EXP
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[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of EXOSC5 mRNA
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CTD |
PMID:17602206 |
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NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046
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