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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fatty acid ester
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Accession:CHEBI:35748 term browser browse the term
Definition:A carboxylic ester in which the carboxylic acid component can be any fatty acid.
Synonyms:related_synonym: a fatty acid ester;   fatty acid esters
 alt_id: CHEBI:27315;   CHEBI:35747;   CHEBI:78205
 chemrof_smiles: *OC(*)=O
 chemrof_formula: CO2R2
 cyclic_relationship: has_functional_parent CHEBI:35366


show annotations for term's descendants           Sort by:
1,2-dibutyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il4 interleukin 4 multiple interactions ISO [dibutyrylglycerol analog co-treated with Fluorescein-5-isothiocyanate] affects the secretion of IL4 protein CTD PMID:29198882 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO dibutyrylglycerol analog results in increased activity of TRPA1 protein CTD PMID:29198882 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
1,2-didecanoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnlip pancreatic lipase increases metabolic processing ISO PNLIP protein results in increased metabolism of 1,2-didecanoylglycerol CTD PMID:9822688 NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:267,784,724...267,797,795 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 increases metabolic processing EXP PNLIPRP2 protein results in increased metabolism of 1,2-didecanoylglycerol CTD PMID:9822688 NCBI chr 1:267,883,906...267,902,572
Ensembl chr 1:267,883,906...267,902,572 		JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO 1,2-didecanoylglycerol results in increased expression of SPRR1A protein CTD PMID:8617999 NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991 		JBrowse link
1,2-dioctanoyl-sn-glycero-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO dioctanoylphosphatidic acid results in increased expression of PTGS2 protein CTD PMID:11854442 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
all-trans-retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP retinol palmitate results in increased activity of CAT protein CTD PMID:20679000 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein] CTD PMID:17377406 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO retinol palmitate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1RN protein] CTD PMID:17377406 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Lipe lipase E, hormone sensitive type increases hydrolysis
multiple interactions 		ISO LIPE protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate] 		CTD PMID:16741517 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression 		EXP retinol palmitate promotes the reaction [EP300 protein binds to MMP9 protein]; retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein]
retinol palmitate results in increased expression of MMP9 mRNA 		CTD PMID:17164434 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Plin3 perilipin 3 multiple interactions ISO PLIN3 protein inhibits the reaction [LIPE protein results in increased hydrolysis of retinol palmitate]; PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] CTD PMID:16741517 NCBI chr 9:1,198,336...1,210,212
Ensembl chr 9:1,198,336...1,210,231 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 increases hydrolysis
multiple interactions 		ISO PNPLA4 protein results in increased hydrolysis of retinol palmitate
PLIN3 protein inhibits the reaction [PNPLA4 protein results in increased hydrolysis of retinol palmitate] 		CTD PMID:16741517 NCBI chr  X:46,200,351...46,205,517
Ensembl chr  X:46,193,332...46,205,089 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP retinol palmitate promotes the reaction [RARA protein binds to MMP9 protein] CTD PMID:17164434 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP retinol palmitate results in increased expression of SCARB1 mRNA CTD PMID:17299104 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
bucladesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with LIPE protein] results in increased expression of ABCA1 protein; Oligomycins inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA] CTD PMID:20083572 PMID:23227865 PMID:23362264 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein] CTD PMID:16452108 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases activity
affects localization
increases expression 		EXP
ISO 		Bucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]
Bucladesine results in increased activity of ABCC2 protein
Bucladesine results in increased expression of ABCC2 mRNA; Bucladesine results in increased expression of ABCC2 protein
Bucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ABCC2 promoter]; Bucladesine results in increased activity of and affects the localization of ABCC2 protein; Dactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]; KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]; verlukast inhibits the reaction [Bucladesine results in increased activity of ABCC2 protein] 		CTD PMID:12029626 PMID:26049102 PMID:29052767 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Ache acetylcholinesterase increases activity
increases expression 		EXP Bucladesine results in increased activity of ACHE protein; Bucladesine results in increased activity of ACHE protein alternative form
Bucladesine results in increased expression of ACHE mRNA 		CTD PMID:18514641 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ADAMTS1 mRNA CTD PMID:20823114 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390 		JBrowse link
G Adm adrenomedullin decreases expression ISO Bucladesine results in decreased expression of ADM mRNA CTD PMID:19253104 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Agt angiotensinogen multiple interactions ISO AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein]; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]] CTD PMID:36682589 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Ahr aryl hydrocarbon receptor affects localization
increases activity
multiple interactions 		ISO Bucladesine affects the localization of AHR protein
Bucladesine results in increased activity of AHR protein
Bucladesine affects the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] 		CTD PMID:15972329 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] CTD PMID:21979172 NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866 		JBrowse link
G Ak5 adenylate kinase 5 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of AK5 mRNA CTD PMID:20823114 NCBI chr 2:244,057,240...244,241,372
Ensembl chr 2:244,057,240...244,241,366 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions ISO [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA CTD PMID:22859313 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642 		JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ANTXR1 mRNA CTD PMID:20823114 NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892 		JBrowse link
G Anxa2 annexin A2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ANXA2 mRNA CTD PMID:20823114 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO 27-hydroxycholesterol promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; 27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA; [Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol; Oligomycins inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 protein]; Probucol inhibits the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; Probucol inhibits the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; T0901317 promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol] CTD PMID:20083572 PMID:23227865 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Ar androgen receptor multiple interactions EXP [Quercetin co-treated with Bucladesine] results in increased expression of AR mRNA CTD PMID:23200735 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ARHGEF2 mRNA CTD PMID:20823114 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein]] CTD PMID:12164941 NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
increases expression 		ISO Bucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ATF2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of ATF2 protein modified form]
Bucladesine results in increased phosphorylation of ATF2 protein 		CTD PMID:26049102 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Atp11a ATPase phospholipid transporting 11A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP11A mRNA CTD PMID:20823114 NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ATP2B1 mRNA CTD PMID:20823114 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ATP6V0C mRNA CTD PMID:20823114 NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein]]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] CTD PMID:16822680 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BCAT1 mRNA CTD PMID:20823114 NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCKDK mRNA CTD PMID:20823114 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression 		ISO adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Bucladesine inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; Bucladesine inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]
Bucladesine results in decreased expression of BCL2 protein 		CTD PMID:10697531 PMID:16822680 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l13 Bcl2-like 13 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BCL2L13 mRNA CTD PMID:20823114 NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:155,728,284...155,781,158 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression 		ISO 1-bromopropane inhibits the reaction [Bucladesine results in increased expression of BDNF mRNA]; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:19189864 PMID:29698629 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BET1L mRNA CTD PMID:20823114 NCBI chr 1:205,361,041...205,365,036
Ensembl chr 1:205,361,041...205,364,706 		JBrowse link
G Bicd1 BICD cargo adaptor 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of BICD1 mRNA CTD PMID:20823114 NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:184,210,363...184,357,391 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO Bucladesine inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] CTD PMID:20522807 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of BSND mRNA CTD PMID:20823114 NCBI chr 5:126,480,590...126,489,389
Ensembl chr 5:126,480,592...126,489,389 		JBrowse link
G C1r complement C1r multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of C1R mRNA CTD PMID:20823114 NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714 		JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CALM1 mRNA CTD PMID:20823114 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calr calreticulin increases stability ISO Bucladesine results in increased stability of CALR protein CTD PMID:9473613 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Capn2 calpain 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAPN2 mRNA CTD PMID:20823114 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein]; Bucladesine promotes the reaction [Hydroxyurea results in increased activity of CASP3 protein] CTD PMID:10697531 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cast calpastatin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CAST mRNA CTD PMID:20823114 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180 		JBrowse link
G Cav2 caveolin 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CAV2 mRNA CTD PMID:20823114 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Bucladesine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein] CTD PMID:12538206 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CCNB1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CCNB1 protein CTD PMID:22534328 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions 		EXP
ISO 		Bucladesine results in increased expression of CCND1 protein
[Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] affects the expression of CCND1 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in decreased expression of CCND1 protein 		CTD PMID:16718685 PMID:21693435 PMID:22534328 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Bucladesine results in increased expression of CCND3 protein CTD PMID:16718685 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Cd69 Cd69 molecule decreases expression ISO Bucladesine results in decreased expression of CD69 protein CTD PMID:25433234 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:12538815 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cdc42bpa CDC42 binding protein kinase alpha multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CDC42BPA mRNA CTD PMID:20823114 NCBI chr13:94,215,359...94,435,681
Ensembl chr13:94,215,959...94,435,681 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions 		EXP
ISO 		Bucladesine results in increased expression of CDKN1A protein
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of CDKN1A mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of CDKN1A protein
GJA1 promotes the reaction [Bucladesine results in increased expression of CDKN1A protein] 		CTD PMID:16718685 PMID:20823114 PMID:22534328 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Bucladesine results in increased expression of CDKN1B protein CTD PMID:16718685 PMID:21693435 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions 		ISO Bucladesine results in increased expression of CEBPB protein
Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein] 		CTD PMID:19282384 PMID:19698295 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cebpz CCAAT/enhancer binding protein zeta multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CEBPZ mRNA CTD PMID:20823114 NCBI chr 6:21,872,071...21,889,755
Ensembl chr 6:21,872,025...21,889,749 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions
increases expression 		ISO
EXP 		[Bucladesine co-treated with Tretinoin] results in increased activity of CHAT protein; [Tretinoin co-treated with Bucladesine] results in increased activity of CHAT protein
Bucladesine results in increased expression of CHAT protein
Nicotine promotes the reaction [Bucladesine results in increased expression of CHAT protein] 		CTD PMID:16724269 PMID:20361958 PMID:29665406 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416 		JBrowse link
G Cldn5 claudin 5 increases expression ISO Bucladesine results in increased expression of CLDN5 mRNA CTD PMID:20711499 NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CNGB1 mRNA CTD PMID:20823114 NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,732,646...9,797,224 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:11576339 PMID:16430859 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA] CTD PMID:11576339 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A2 mRNA CTD PMID:20823114 NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of COL6A3 mRNA CTD PMID:20823114 NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of COX6A2 mRNA CTD PMID:20823114 NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716 		JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CPLX1 mRNA CTD PMID:20823114 NCBI chr14:1,329,073...1,360,781
Ensembl chr14:1,329,032...1,360,769 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions 		ISO Bucladesine results in increased phosphorylation of CREB1 protein
[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]
[Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein] 		CTD PMID:12164941 PMID:18787026 PMID:19282384 PMID:36565944 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crebbp CREB binding protein multiple interactions ISO [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; Bucladesine promotes the reaction [CREBBP protein binds to SOD2 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]
[Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]] 		CTD PMID:19282384 PMID:20685861 PMID:36565944 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CREM mRNA CTD PMID:20823114 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Bucladesine inhibits the reaction [arsenite results in increased expression of CRYAB protein] CTD PMID:8769853 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO Bucladesine promotes the reaction [Tretinoin results in increased expression of CSF1R mRNA] CTD PMID:8445950 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806 		JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions
affects localization 		ISO Bucladesine inhibits the reaction [CTBP1 protein binds to KAT2A protein]; Bucladesine inhibits the reaction [CTBP1 protein binds to NR5A1 protein]; Bucladesine promotes the reaction [CTBP1 protein binds to CTBP2 protein]
Bucladesine affects the localization of CTBP1 protein 		CTD PMID:18184656 NCBI chr14:81,679,956...81,707,331
Ensembl chr14:81,679,765...81,707,554 		JBrowse link
G Ctbp2 C-terminal binding protein 2 affects localization
multiple interactions 		ISO Bucladesine affects the localization of CTBP2 protein
Bucladesine promotes the reaction [CTBP1 protein binds to CTBP2 protein] 		CTD PMID:18184656 NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261 		JBrowse link
G Ctnnb1 catenin beta 1 increases phosphorylation EXP Bucladesine results in increased phosphorylation of CTNNB1 protein CTD PMID:26964897 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctps2 CTP synthase 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of CTPS2 mRNA CTD PMID:20823114 NCBI chr  X:35,277,658...35,418,505
Ensembl chr  X:35,277,658...35,418,505 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Bucladesine results in decreased expression of CXCL12 mRNA CTD PMID:20711499 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cyb5d1 cytochrome b5 domain containing 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CYB5D1 mRNA CTD PMID:20823114 NCBI chr10:54,612,230...54,616,375
Ensembl chr10:54,612,230...54,616,713 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression
multiple interactions 		EXP
ISO 		Bucladesine results in increased expression of CYP11A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP11A1 mRNA]
[Atrazine co-treated with Bucladesine] results in increased expression of CYP11A1 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of CYP11A1 mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP11A1 mRNA] 		CTD PMID:21693180 PMID:21979172 PMID:23200735 PMID:35987080 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of CYP11B1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP11B1 mRNA] 		CTD PMID:35987080 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions
increases expression 		ISO fluorene-9-bisphenol affects the reaction [Bucladesine results in increased expression of CYP11B2 mRNA] CTD PMID:35987080 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
increases expression
multiple interactions 		EXP
ISO 		Bucladesine results in decreased expression of CYP17A1 mRNA
Bucladesine results in increased expression of CYP17A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP17A1 mRNA]
[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of CYP17A1 mRNA] 		CTD PMID:21458522 PMID:21693180 PMID:23200735 PMID:35987080 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of CYP19A1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of CYP19A1 mRNA] 		CTD PMID:35987080 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP
ISO 		Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Bucladesine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] 		CTD PMID:1849469 PMID:16901605 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Bucladesine results in increased expression of CYP1B1 mRNA CTD PMID:11559018 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol] CTD PMID:8531136 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Dcn decorin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DCN protein] CTD PMID:20823114 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926 		JBrowse link
G Ddx27 DEAD-box helicase 27 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of DDX27 mRNA CTD PMID:20823114 NCBI chr 3:176,163,220...176,182,418
Ensembl chr 3:176,163,203...176,182,410 		JBrowse link
G Des desmin multiple interactions EXP
ISO 		[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of DES mRNA
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA 		CTD PMID:19089455 PMID:20823114 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347 		JBrowse link
G Dhx9 DExH-box helicase 9 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DHX9 mRNA CTD PMID:20823114 NCBI chr13:68,152,813...68,189,580
Ensembl chr13:68,152,813...68,189,546 		JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DIO2 mRNA CTD PMID:20823114 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Dtymk deoxythymidylate kinase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of DTYMK mRNA CTD PMID:20823114 NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504 		JBrowse link
G Eda ectodysplasin-A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EDA mRNA CTD PMID:20823114 NCBI chr  X:69,118,577...69,520,274
Ensembl chr  X:69,118,796...69,520,274 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA CTD PMID:20823114 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EFEMP1 mRNA CTD PMID:20823114 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EGR2 mRNA CTD PMID:20823114 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748 		JBrowse link
G Eno2 enolase 2 multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA CTD PMID:29698629 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220 		JBrowse link
G Epb41l4a erythrocyte membrane protein band 4.1 like 4A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPB41L4A mRNA CTD PMID:20823114 NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of EPHA3 mRNA CTD PMID:20823114 NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425 		JBrowse link
G Esr1 estrogen receptor 1 increases expression
multiple interactions 		EXP Bucladesine results in increased expression of ESR1 mRNA
[Quercetin co-treated with Bucladesine] results in increased expression of ESR1 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of ESR1 mRNA] 		CTD PMID:21693180 PMID:23200735 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EYA1 mRNA CTD PMID:20823114 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:9,646,591...9,884,614 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] CTD PMID:36565944 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183 		JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FADS2 mRNA CTD PMID:20823114 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions 		EXP Bucladesine results in increased expression of FAS mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of FAS mRNA] 		CTD PMID:12414803 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Fbxo11 F-box protein 11 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXO11 mRNA CTD PMID:20823114 NCBI chr 6:12,240,348...12,316,223
Ensembl chr 6:12,239,801...12,316,221 		JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FBXW5 mRNA CTD PMID:20823114 NCBI chr 3:28,720,670...28,725,237
Ensembl chr 3:28,720,778...28,725,235 		JBrowse link
G Fcer2 Fc epsilon receptor II decreases expression ISO Bucladesine results in decreased expression of FCER2 protein CTD PMID:1328389 NCBI chr12:6,540,697...6,552,364
Ensembl chr12:6,540,703...6,549,374 		JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FGD1 mRNA CTD PMID:20823114 NCBI chr  X:23,466,791...23,509,773
Ensembl chr  X:23,467,530...23,509,979 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions ISO FGF9 protein inhibits the reaction [Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; FGF9 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone] CTD PMID:22798350 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926 		JBrowse link
G Filip1l filamin A interacting protein 1-like multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FILIP1L mRNA CTD PMID:20823114 NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [bisphenol A co-treated with Bucladesine] results in increased methylation of FKBP5 intron; [Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 mRNA; [Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 protein; [Bucladesine co-treated with Dexamethasone] results in increased expression of FKBP5 mRNA; [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA; [Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 protein; [fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron; bisphenol A promotes the reaction [[fulvestrant co-treated with Bucladesine] results in increased methylation of FKBP5 intron]; Dexamethasone inhibits the reaction [[Bucladesine co-treated with bisphenol A] results in decreased expression of FKBP5 mRNA]; Estradiol inhibits the reaction [[Bucladesine co-treated with fulvestrant] results in decreased expression of FKBP5 mRNA] CTD PMID:26427651 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of FN1 mRNA CTD PMID:20823114 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
increases expression 		ISO Bucladesine affects the expression of FOS protein
Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]
Bucladesine results in increased expression of FOS mRNA; Bucladesine results in increased expression of FOS protein 		CTD PMID:7798212 PMID:9187264 PMID:19282384 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of FOXO1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FOXO1 mRNA; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of and results in increased localization of FOXO1 protein] CTD PMID:20823114 PMID:36682589 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of FSCN2 mRNA CTD PMID:20823114 NCBI chr10:106,121,038...106,139,683
Ensembl chr10:106,133,144...106,139,683 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
increases expression 		ISO IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of G6PC1 mRNA]; STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]]
Bucladesine results in increased expression of G6PC1 mRNA; Bucladesine results in increased expression of G6PC1 protein 		CTD PMID:22859313 PMID:26064446 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GARS1 mRNA CTD PMID:20823114 NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GBE1 mRNA CTD PMID:20823114 NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638 		JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GBP2 mRNA CTD PMID:20823114 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GCNT2 mRNA CTD PMID:20823114 NCBI chr17:24,002,592...24,107,339
Ensembl chr17:24,002,597...24,106,989 		JBrowse link
G Gdf3 growth differentiation factor 3 affects expression
multiple interactions 		ISO Bucladesine affects the expression of GDF3 mRNA; Bucladesine affects the expression of GDF3 protein
bisphenol A affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of GDF3 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of GDF3 protein]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 protein] 		CTD PMID:31400064 NCBI chr 4:157,503,547...157,507,923
Ensembl chr 4:157,502,884...157,507,907 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions ISO [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the phosphorylation of CREB1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] CTD PMID:36565944 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GIPC1 mRNA CTD PMID:20823114 NCBI chr19:41,380,125...41,392,078
Ensembl chr19:41,380,125...41,391,725 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression 		EXP GJA1 promotes the reaction [Bucladesine results in increased expression of CDKN1A protein]; Tolbutamide promotes the reaction [Bucladesine results in increased expression of GJA1 protein] CTD PMID:11741589 PMID:16718685 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions ISO Bucladesine promotes the reaction [Bezafibrate results in increased expression of GPD1 mRNA] CTD PMID:1976021 NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368 		JBrowse link
G Gpkow G patch domain and KOW motifs multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of GPKOW mRNA CTD PMID:20823114 NCBI chr  X:17,463,521...17,478,298
Ensembl chr  X:17,463,525...17,478,298 		JBrowse link
G Gpnmb glycoprotein nmb multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of GPNMB mRNA CTD PMID:20823114 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
increases expression 		ISO KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA1 mRNA] CTD PMID:26049102 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of GSTA2 mRNA
KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA2 mRNA] 		CTD PMID:26049102 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of GSTA4 mRNA
KT 5720 inhibits the reaction [Bucladesine results in increased expression of GSTA4 mRNA] 		CTD PMID:26049102 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Bucladesine results in increased expression of HIF1A mRNA CTD PMID:18591213 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression 		ISO [tris(2-butoxyethyl) phosphate co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1,3-dichloro-2-propyl)phosphate co-treated with santicizer 148 co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] inhibits the reaction [Bucladesine results in increased expression of HMGCR mRNA]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of HMGCR mRNA] CTD PMID:35987080 PMID:38603619 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of HOXA1 mRNA] CTD PMID:20823114 NCBI chr 4:82,586,505...82,589,209
Ensembl chr 4:82,586,505...82,589,209 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases expression
multiple interactions 		ISO Bucladesine results in decreased expression of HSD17B1 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in decreased expression of HSD17B1 mRNA] 		CTD PMID:35987080 NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,510,011...86,512,210 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression EXP Bucladesine results in increased expression of HSD17B12 mRNA CTD PMID:21458522 NCBI chr 3:100,445,393...100,568,898
Ensembl chr 3:100,445,400...100,568,938 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP Bucladesine results in increased expression of HSD3B1 mRNA CTD PMID:21458522 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of HSD3B2 mRNA
fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of HSD3B2 mRNA] 		CTD PMID:35987080 NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression
increases phosphorylation 		EXP
ISO 		Bucladesine results in increased expression of HSP27 protein
Bucladesine results in increased phosphorylation of HSPB1 protein 		CTD PMID:7541446 PMID:10559386 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of HTR1A mRNA CTD PMID:20823114 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760 		JBrowse link
G Iapp islet amyloid polypeptide increases expression EXP Bucladesine results in increased expression of IAPP mRNA CTD PMID:9142872 NCBI chr 4:176,968,097...176,975,363
Ensembl chr 4:176,968,097...176,975,363 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] CTD PMID:12538815 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of ID1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ID1 mRNA] 		CTD PMID:20522807 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IFRD2 mRNA CTD PMID:20823114 NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]; FGF9 protein inhibits the reaction [Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol]]; FGF9 protein inhibits the reaction [IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone]]; IGF1 protein promotes the reaction [Bucladesine results in increased abundance of Progesterone] CTD PMID:22798350 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of IGFBP1
[Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 mRNA]; Azacitidine promotes the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP1 protein] 		CTD PMID:12093828 PMID:20823114 PMID:30328349 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP3 mRNA CTD PMID:20823114 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IGFBP4 mRNA CTD PMID:20823114 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]] CTD PMID:12230500
G Il10 interleukin 10 decreases expression
multiple interactions 		ISO Bucladesine results in decreased expression of IL10
Bucladesine promotes the reaction [Zymosan results in increased expression of IL10 protein] 		CTD PMID:11301049 PMID:19273625 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IL12B mRNA CTD PMID:20823114 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13 interleukin 13 decreases expression
decreases secretion 		ISO Bucladesine results in decreased expression of IL13 mRNA
Bucladesine results in decreased secretion of IL13 protein 		CTD PMID:16083514 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Bucladesine promotes the reaction [IL1B protein results in increased abundance of Nitrites]; Dipyridamole promotes the reaction [Bucladesine promotes the reaction [IL1B protein results in increased abundance of Nitrites]] CTD PMID:8904084 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression
multiple interactions 		ISO Bucladesine results in increased expression of IL23A mRNA
[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of IL23A mRNA 		CTD PMID:19273625 PMID:20823114 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression ISO Bucladesine results in decreased expression of IL2RA protein CTD PMID:1709825 PMID:25433234 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO Bucladesine inhibits the reaction [Itraconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [terbinafine results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [terbinafine results in decreased secretion of IL4 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL4 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL4 protein] CTD PMID:11886533 PMID:12230500 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO Bucladesine inhibits the reaction [Itraconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Itraconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Ketoconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Ketoconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Miconazole results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Miconazole results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [terbinafine results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [terbinafine results in decreased secretion of IL5 protein]; Bucladesine inhibits the reaction [Tolnaftate results in decreased expression of IL5 mRNA]; Bucladesine inhibits the reaction [Tolnaftate results in decreased secretion of IL5 protein] CTD PMID:11886533 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Bucladesine co-treated with Theophylline] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:20388727 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inha inhibin subunit alpha decreases expression
multiple interactions 		EXP Bucladesine results in decreased expression of INHA mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of INHA mRNA; Atrazine inhibits the reaction [Bucladesine results in decreased expression of INHA mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of INHA mRNA] 		CTD PMID:21693180 PMID:23200735 NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009 		JBrowse link
G Insl3 insulin-like 3 multiple interactions
increases expression 		EXP [Atrazine co-treated with Bucladesine] results in increased expression of INSL3 mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of INSL3 mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of INSL3 mRNA] CTD PMID:21458522 PMID:21693180 PMID:23200735 NCBI chr16:18,432,668...18,434,539 JBrowse link
G Ints7 integrator complex subunit 7 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA CTD PMID:20823114 NCBI chr13:105,686,208...105,739,609
Ensembl chr13:105,686,128...105,739,608 		JBrowse link
G Irf9 interferon regulatory factor 9 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of IRF9 mRNA CTD PMID:20823114 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ISG20L2 mRNA CTD PMID:20823114 NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095 		JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITGB1 mRNA CTD PMID:20823114 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Itih5 inter-alpha-trypsin inhibitor heavy chain 5 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of ITIH5 mRNA CTD PMID:20823114 NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO Bucladesine results in increased expression of JUN mRNA; Bucladesine results in increased expression of JUN protein
Bucladesine results in increased expression of JUN protein; Bucladesine results in increased expression of JUN protein modified form
Bucladesine promotes the reaction [JUN protein binds to ABCC2 promoter]; Bucladesine promotes the reaction [JUN protein binds to ATF2 protein]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein modified form]; KT 5720 inhibits the reaction [Bucladesine results in increased expression of JUN protein]
[Bucladesine co-treated with ciglitazone] results in increased expression of and results in increased phosphorylation of JUN protein; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of JUN mRNA]; Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein; ciglitazone promotes the reaction [Bucladesine results in increased expression of JUN mRNA]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein] 		CTD PMID:9187264 PMID:18755854 PMID:19282384 PMID:19698295 PMID:26049102 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kat2a lysine acetyltransferase 2A multiple interactions ISO Bucladesine inhibits the reaction [CTBP1 protein binds to KAT2A protein] CTD PMID:18184656 NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485 		JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KCNC4 mRNA CTD PMID:20823114 NCBI chr 2:197,747,095...197,788,467
Ensembl chr 2:197,759,010...197,788,433 		JBrowse link
G Kng1 kininogen 1 increases activity EXP Bucladesine results in increased activity of KNG1 CTD PMID:1334751 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148 		JBrowse link
G Krt8 keratin 8 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA; Azacitidine inhibits the reaction [[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of KRT8 mRNA] CTD PMID:20823114 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Lamb2 laminin subunit beta 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LAMB2 mRNA CTD PMID:20823114 NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LDHA mRNA CTD PMID:20823114 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Lep leptin decreases expression ISO Bucladesine results in decreased expression of LEP mRNA CTD PMID:9002984 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lgals3 galectin 3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of LGALS3 mRNA CTD PMID:20823114 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression
multiple interactions 		EXP Bucladesine results in decreased expression of LHCGR mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of LHCGR mRNA; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of LHCGR mRNA] 		CTD PMID:21693180 PMID:23200735 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061 		JBrowse link
G Lipe lipase E, hormone sensitive type affects localization
increases activity
increases expression
multiple interactions 		EXP
ISO 		Bucladesine affects the localization of LIPE protein
Bucladesine results in increased activity of LIPE protein
Bucladesine results in increased expression of LIPE mRNA
[Bucladesine co-treated with LIPE protein] results in increased expression of ABCA1 protein; [Bucladesine co-treated with LIPE protein] results in increased expression of and results in increased phosphorylation of STAR protein; Bucladesine results in increased expression of and results in increased phosphorylation of LIPE protein; CAY 10499 inhibits the reaction [Bucladesine results in increased activity of and results in increased phosphorylation of LIPE protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of PLIN1 mRNA]; LIPE protein affects the reaction [Bucladesine results in increased expression of SCARB1 mRNA]; LIPE protein affects the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of LIPE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of LIPE mRNA]; NR1H2 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]]; NR1H3 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]] 		CTD PMID:11160373 PMID:23362264 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117 		JBrowse link
G LOC120095955 mucin-12-like multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MUC12 mRNA CTD PMID:20823114 NCBI chr12:25,127,100...25,137,925 JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LPAR3 mRNA CTD PMID:20823114 NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of LTBP1 mRNA CTD PMID:20823114 NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036 		JBrowse link
G Ltc4s leukotriene C4 synthase decreases secretion ISO Bucladesine results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr10:35,060,002...35,066,466
Ensembl chr10:35,061,437...35,063,768 		JBrowse link
G Map1a microtubule-associated protein 1A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MAP1A mRNA CTD PMID:20823114 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA CTD PMID:29698629 NCBI chr 9:75,173,038...75,431,606
Ensembl chr 9:75,288,262...75,428,459 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MAP4K4 mRNA CTD PMID:20823114 NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK1 protein]; [1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK1 protein
Bucladesine results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Bucladesine results in increased phosphorylation of MAPK1 protein]; Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein]] 		CTD PMID:8526880 PMID:19282384 PMID:22875961 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		ISO 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK3 protein]; [1-Methyl-3-isobutylxanthine co-treated with Bucladesine] results in increased activity of MAPK3 protein
Bucladesine results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Bucladesine results in increased phosphorylation of MAPK3 protein]; Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein]] 		CTD PMID:8526880 PMID:19282384 PMID:22875961 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MGAT4B mRNA CTD PMID:20823114 NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309 		JBrowse link
G Mir125a microRNA 125a decreases expression EXP
ISO 		Bucladesine results in decreased expression of MIR125A mRNA CTD PMID:23045399 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759 		JBrowse link
G Mir145 microRNA 145 decreases expression EXP
ISO 		Bucladesine results in decreased expression of MIR145 mRNA CTD PMID:23045399 NCBI chr18:57,369,983...57,370,070 JBrowse link
G Mir27b microRNA 27b multiple interactions ISO [Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MIR27B mRNA CTD PMID:30328349 NCBI chr17:1,819,147...1,819,243 JBrowse link
G Mir455 microRNA 455 decreases expression EXP
ISO 		Bucladesine results in decreased expression of MIR455 mRNA CTD PMID:23045399 NCBI chr 5:81,704,834...81,704,911
Ensembl chr 5:81,704,834...81,704,911 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Bucladesine results in decreased expression of MKI67 protein CTD PMID:16718685 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of MMP2 mRNA CTD PMID:20823114 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTHFD2 mRNA CTD PMID:20823114 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MTR mRNA CTD PMID:20823114 NCBI chr17:62,911,705...62,996,544
Ensembl chr17:62,911,771...62,996,541 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Bucladesine results in decreased expression of MYC mRNA; Bucladesine results in decreased expression of MYC protein CTD PMID:7798212 PMID:9187264 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myh9 myosin, heavy chain 9 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYH9 mRNA CTD PMID:20823114 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963 		JBrowse link
G Myl12a myosin light chain 12A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12A mRNA CTD PMID:20823114 NCBI chr 9:118,338,592...118,346,277
Ensembl chr 9:118,338,604...118,342,634 		JBrowse link
G Myl12b myosin light chain 12B multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYL12B mRNA CTD PMID:20823114 NCBI chr 9:118,320,479...118,334,810
Ensembl chr 9:118,320,489...118,324,418 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYLK mRNA CTD PMID:20823114 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Myof myoferlin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of MYOF mRNA CTD PMID:20823114 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NCF1 mRNA CTD PMID:20823114 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NDST1 mRNA CTD PMID:20823114 NCBI chr18:56,407,308...56,470,007
Ensembl chr18:56,411,200...56,448,612 		JBrowse link
G Nefl neurofilament light chain multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA CTD PMID:29698629 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515 		JBrowse link
G Nefm neurofilament medium chain multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163 		JBrowse link
G Neurog1 neurogenin 1 multiple interactions
affects expression 		ISO bisphenol A affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of NEUROG1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of NEUROG1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of NEUROG1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of NEUROG1 protein]
Bucladesine affects the expression of NEUROG1 mRNA; Bucladesine affects the expression of NEUROG1 protein 		CTD PMID:31400064 NCBI chr17:8,368,096...8,369,615
Ensembl chr17:8,368,096...8,369,615 		JBrowse link
G Nexn nexilin (F actin binding protein) multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NEXN mRNA CTD PMID:20823114 NCBI chr 2:243,846,736...243,878,268
Ensembl chr 2:243,846,433...243,887,114 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases response to substance 		ISO [NFE2L2 gene mutant form results in increased susceptibility to Bucladesine] which results in increased expression of ALAS1 mRNA; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of CYP2A5 mRNA]; NFE2L2 gene mutant form promotes the reaction [Bucladesine results in increased expression of G6PC1 mRNA] CTD PMID:22859313 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Ngf nerve growth factor multiple interactions ISO [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of ENO2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of MAP2 mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFL mRNA; [Bucladesine co-treated with 1-Methyl-3-isobutylxanthine co-treated with EGF protein co-treated with FGF2 protein co-treated with NGF protein co-treated with BDNF protein] results in increased expression of NEFM mRNA CTD PMID:29698629 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NOM1 mRNA CTD PMID:20823114 NCBI chr 4:6,562,931...6,586,093
Ensembl chr 4:6,567,836...6,585,036 		JBrowse link
G Nphp1 nephrocystin 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NPHP1 mRNA CTD PMID:20823114 NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:135,413,927...135,469,505 		JBrowse link
G Nptxr neuronal pentraxin receptor multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NPTXR mRNA CTD PMID:20823114 NCBI chr 7:113,217,046...113,235,122
Ensembl chr 7:113,217,050...113,235,156 		JBrowse link
G Npy neuropeptide Y increases expression EXP Bucladesine results in increased expression of NPY mRNA CTD PMID:19912776 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression
multiple interactions 		ISO Bucladesine results in decreased expression of NR0B1 mRNA; Bucladesine results in decreased expression of NR0B1 protein
Cycloheximide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 protein]; NR0B1 protein inhibits the reaction [[Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [Bucladesine results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]] 		CTD PMID:18787026 PMID:19282384 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO NR1H2 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]] CTD PMID:23362264 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO NR1H3 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased phosphorylation of LIPE protein]] CTD PMID:23362264 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NR2F1 mRNA CTD PMID:20823114 NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:9,776,179...9,785,924 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions
increases expression 		ISO NR0B1 protein inhibits the reaction [Bucladesine results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein]
[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]; [Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 mRNA]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the expression of NR4A1 protein]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the methylation of NR4A1 promoter]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREB1 protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [CREBBP protein binds to NR4A1 promoter]]; methylmercuric chloride affects the reaction [[Doxycycline co-treated with Bucladesine co-treated with GDNF protein] affects the reaction [EZH2 protein binds to NR4A1 promoter]] 		CTD PMID:18787026 PMID:19282384 PMID:36565944 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions
increases expression 		ISO Bucladesine inhibits the reaction [CTBP1 protein binds to NR5A1 protein]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of NR5A1 mRNA]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of NR5A1 protein]
Bucladesine results in increased expression of NR5A1 mRNA; Bucladesine results in increased expression of NR5A1 protein
NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA] 		CTD PMID:18184656 PMID:18787026 PMID:35987080 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NRIP1 mRNA CTD PMID:20823114 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of NT5E mRNA CTD PMID:20823114 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645 		JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Bucladesine results in increased expression of NTF3 protein CTD PMID:19854260 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Nts neurotensin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NTS mRNA CTD PMID:20823114 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961 		JBrowse link
G Nup155 nucleoporin 155 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of NUP155 mRNA CTD PMID:20823114 NCBI chr 2:58,927,171...58,980,162
Ensembl chr 2:58,928,537...58,981,242 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
decreases activity 		ISO 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone promotes the reaction [Bucladesine results in decreased activity of ODC1 protein] CTD PMID:6284819 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogfrl1 opioid growth factor receptor-like 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OGFRL1 mRNA CTD PMID:20823114 NCBI chr 9:33,320,501...33,338,742
Ensembl chr 9:33,324,392...33,339,237 		JBrowse link
G Or8b8 olfactory receptor family 8 subfamily B member 8 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of OR8B8 mRNA CTD PMID:20823114 NCBI chr 8:45,882,321...45,883,253
Ensembl chr 8:45,882,321...45,883,253 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of P4HB mRNA CTD PMID:20823114 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911 		JBrowse link
G Paep progestagen associated endometrial protein multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PAEP mRNA CTD PMID:20823114 NCBI chr 3:28,929,252...28,932,592 JBrowse link
G Pakap paralemmin A kinase anchor protein multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PALM2AKAP2 mRNA CTD PMID:20823114 NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656 		JBrowse link
G Pax6 paired box 6 multiple interactions
affects expression 		ISO bisphenol A affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of PAX6 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of PAX6 protein]; Paraquat affects the reaction [Bucladesine affects the expression of PAX6 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of PAX6 protein]
Bucladesine affects the expression of PAX6 mRNA; Bucladesine affects the expression of PAX6 protein 		CTD PMID:31400064 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763 		JBrowse link
G Pcdh18 protocadherin 18 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDH18 mRNA CTD PMID:20823114 NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826 		JBrowse link
G Pcdhb5 protocadherin beta 5 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PCDHB4 mRNA CTD PMID:20823114 NCBI chr18:29,302,466...29,305,048 JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions
increases expression 		ISO
EXP 		Metformin inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA]
Lithium Chloride inhibits the reaction [Bucladesine results in increased expression of PCK1 mRNA] 		CTD PMID:1371108 PMID:24428821 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pdgfa platelet derived growth factor subunit A decreases expression ISO Bucladesine results in decreased expression of PDGFA mRNA CTD PMID:1650039 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PDK1 mRNA CTD PMID:20823114 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145 		JBrowse link
G Pf4 platelet factor 4 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of PF4 mRNA
[Bucladesine co-treated with Tetrachlorodibenzodioxin] results in increased expression of PF4 mRNA 		CTD PMID:21979172 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PGRMC2 mRNA CTD PMID:20823114 NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:125,996,193...126,012,090 		JBrowse link
G Pitpnc1 phosphatidylinositol transfer protein, cytoplasmic 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PITPNC1 mRNA CTD PMID:20823114 NCBI chr10:92,663,260...92,928,616
Ensembl chr10:92,663,260...92,928,344 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PKD2L1 mRNA CTD PMID:20823114 NCBI chr 1:252,982,096...253,019,235
Ensembl chr 1:252,982,096...253,023,359 		JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLAT mRNA CTD PMID:20823114 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plekhg3 pleckstrin homology and RhoGEF domain containing G3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PLEKHG3 mRNA CTD PMID:20823114 NCBI chr 6:100,998,965...101,042,120
Ensembl chr 6:100,994,417...101,042,118 		JBrowse link
G Plin1 perilipin 1 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of PLIN1 mRNA
LIPE protein affects the reaction [Bucladesine results in increased expression of PLIN1 mRNA] 		CTD PMID:23362264 NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206 		JBrowse link
G Pls3 plastin 3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PLS3 mRNA CTD PMID:20823114 NCBI chr  X:116,401,247...116,495,898
Ensembl chr  X:116,401,293...116,495,893 		JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions
increases activity 		ISO Ascorbic Acid inhibits the reaction [Bucladesine results in increased activity of PMP22 promoter] CTD PMID:15034573 NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940 		JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 increases expression
multiple interactions 		ISO Bucladesine results in increased expression of PNPLA6 mRNA
Bucladesine results in increased expression of and results in increased activity of PNPLA6 protein; Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein] 		CTD PMID:20380879 NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631 		JBrowse link
G Pomc proopiomelanocortin increases expression ISO Bucladesine results in increased expression of POMC mRNA; Bucladesine results in increased expression of POMC protein modified form CTD PMID:1325994 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects expression
multiple interactions 		ISO Bucladesine affects the expression of POU5F1 mRNA; Bucladesine affects the expression of POU5F1 protein
bisphenol A affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of POU5F1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of POU5F1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of POU5F1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of POU5F1 protein] 		CTD PMID:31400064 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions 		ISO Bucladesine results in increased expression of PPARG protein
[ciglitazone co-treated with Bucladesine] affects the expression of PPARG mRNA; [ciglitazone co-treated with Bucladesine] results in increased expression of PPARG protein 		CTD PMID:19698295 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions 		ISO Bucladesine results in increased expression of PPARGC1A mRNA; Bucladesine results in increased expression of PPARGC1A protein
IL22 protein inhibits the reaction [Bucladesine results in increased expression of PPARGC1A protein]; Metformin inhibits the reaction [Bucladesine results in increased expression of PPARGC1A mRNA] 		CTD PMID:24428821 PMID:26064446 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PPIA mRNA CTD PMID:20823114 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115 		JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP Bucladesine results in increased expression of PRIMA1 mRNA CTD PMID:18514641 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:128,103,175...128,154,865 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions
increases activity 		EXP KT 5720 inhibits the reaction [Bucladesine results in increased activity of PRKACA protein] CTD PMID:31300867 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prl prolactin multiple interactions ISO [Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of PRL protein; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA; [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL protein; [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein; AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]; Losartan inhibits the reaction [AGT protein promotes the reaction [[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased secretion of PRL protein]] CTD PMID:20823114 PMID:30328349 PMID:36682589 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Prl8a2 prolactin family 8, subfamily A, member 2 multiple interactions EXP [Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of PRL8A2 mRNA CTD PMID:19089455 NCBI chr17:37,821,651...37,830,676
Ensembl chr17:37,821,651...37,830,676 		JBrowse link
G Prss12 serine protease 12 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of PRSS12 mRNA CTD PMID:20823114 NCBI chr 2:214,308,695...214,368,679
Ensembl chr 2:214,308,774...214,369,941 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 mRNA]]; Bucladesine inhibits the reaction [Ketoconazole inhibits the reaction [Dinoprostone results in increased expression of PTGS2 protein]]; Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]
Bucladesine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] 		CTD PMID:11095985 PMID:12164941 PMID:24003391 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptk7 protein tyrosine kinase 7 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTK7 mRNA CTD PMID:20823114 NCBI chr 9:21,849,756...21,916,077
Ensembl chr 9:21,849,801...21,916,078 		JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of PTPA mRNA CTD PMID:20823114 NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:34,087,575...34,162,772 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB1B mRNA CTD PMID:20823114 NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337
Ensembl chr  X:211,835,073...211,843,337 		JBrowse link
G Rab31 RAB31, member RAS oncogene family multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RAB31 mRNA CTD PMID:20823114 NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092 		JBrowse link
G Ran RAN, member RAS oncogene family multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RAN mRNA CTD PMID:20823114 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases activity
decreases phosphorylation
multiple interactions 		ISO
EXP 		Bucladesine results in decreased activity of RB1 protein
Bucladesine results in decreased phosphorylation of RB1 protein
Bucladesine inhibits the reaction [CASP3 protein results in increased cleavage of RB1 protein] 		CTD PMID:10697531 PMID:16718685 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Ren renin increases secretion
increases expression 		ISO Bucladesine results in increased secretion of REN protein
Bucladesine results in increased expression of REN mRNA 		CTD PMID:9256163 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RET mRNA CTD PMID:20823114 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RGS10 mRNA CTD PMID:20823114 NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RHOBTB3 mRNA CTD PMID:20823114 NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906 		JBrowse link
G Rin1 Ras and Rab interactor 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RIN1 mRNA CTD PMID:20823114 NCBI chr 1:211,785,107...211,789,755
Ensembl chr 1:211,784,943...211,791,368 		JBrowse link
G Rpn1 ribophorin I multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPN1 mRNA CTD PMID:20823114 NCBI chr 4:122,100,976...122,122,382
Ensembl chr 4:122,100,813...122,122,382 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of RPS6KB1 mRNA CTD PMID:20823114 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Rpsa ribosomal protein SA multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of RPSA mRNA CTD PMID:20823114 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737 		JBrowse link
G S100a14 S100 calcium binding protein A14 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of S100A14 mRNA CTD PMID:20823114 NCBI chr 2:178,305,976...178,308,004
Ensembl chr 2:178,306,025...178,307,999 		JBrowse link
G Saraf store-operated calcium entry-associated regulatory factor multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SARAF mRNA CTD PMID:20823114 NCBI chr16:64,720,404...64,738,653
Ensembl chr16:64,720,418...64,738,653 		JBrowse link
G Scamp4 secretory carrier membrane protein 4 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SCAMP4 mRNA CTD PMID:20823114 NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
increases expression 		ISO
EXP 		LIPE protein affects the reaction [Bucladesine results in increased expression of SCARB1 mRNA] CTD PMID:23045399 PMID:23362264 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Sdcbp syndecan binding protein multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SDCBP mRNA CTD PMID:20823114 NCBI chr 5:24,245,279...24,314,712
Ensembl chr 5:24,245,033...24,326,197 		JBrowse link
G Selenot selenoprotein T multiple interactions
increases expression 		EXP 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Bucladesine results in increased expression of SELENOT mRNA]; nickel chloride inhibits the reaction [Bucladesine results in increased expression of SELENOT mRNA] CTD PMID:18198219 NCBI chr 2:144,954,324...144,971,375
Ensembl chr 2:144,954,312...144,971,369 		JBrowse link
G Sema3a semaphorin 3A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of SEMA3A mRNA CTD PMID:20823114 NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:22,245,322...22,535,774 		JBrowse link
G Septin11 septin 11 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SEPTIN11 mRNA CTD PMID:20823114 NCBI chr14:15,119,760...15,275,222
Ensembl chr14:15,128,951...15,275,200 		JBrowse link
G Sfn stratifin multiple interactions ISO [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of SFN mRNA; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of SFN protein CTD PMID:22534328 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Sik3 SIK family kinase 3 multiple interactions
increases phosphorylation 		ISO yakuchinone-A inhibits the reaction [Bucladesine results in increased phosphorylation of SIK3 protein] CTD PMID:38164184 NCBI chr 8:55,208,969...55,419,138
Ensembl chr 8:55,208,815...55,419,138 		JBrowse link
G Slc18a3 solute carrier family 18 member A3 increases expression
multiple interactions 		EXP Bucladesine results in increased expression of SLC18A3 protein
Nicotine promotes the reaction [Bucladesine results in increased expression of SLC18A3 protein] 		CTD PMID:20361958 NCBI chr16:7,719,953...7,722,814 JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Progesterone co-treated with Bucladesine] results in increased expression of SLC2A1 protein CTD PMID:18948400 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions ISO Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA] CTD PMID:12820898 NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:165,866,172...165,894,038 		JBrowse link
G Smad6 SMAD family member 6 multiple interactions ISO Bucladesine inhibits the reaction [BMP4 protein results in increased expression of SMAD6 mRNA] CTD PMID:20522807 NCBI chr 8:73,345,457...73,414,985
Ensembl chr 8:73,345,460...73,414,149 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
increases activity 		ISO Bucladesine promotes the reaction [CREBBP protein binds to SOD2 promoter]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of SOD2 mRNA]; protein kinase inhibitor peptide inhibits the reaction [Bucladesine results in increased activity of SOD2 protein] CTD PMID:12093828 PMID:20685861 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sox1 SRY-box transcription factor 1 multiple interactions
affects expression 		ISO bisphenol A affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; bisphenol A affects the reaction [Bucladesine affects the expression of SOX1 protein]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; Methylmercury Compounds affects the reaction [Bucladesine affects the expression of SOX1 protein]; Paraquat affects the reaction [Bucladesine affects the expression of SOX1 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of SOX1 protein]
Bucladesine affects the expression of SOX1 mRNA; Bucladesine affects the expression of SOX1 protein 		CTD PMID:31400064 NCBI chr16:83,837,689...83,841,703
Ensembl chr16:83,802,160...83,841,775 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression 		ISO Organophosphates inhibits the reaction [Bucladesine results in increased expression of SREBF2 mRNA] CTD PMID:38603619 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SRSF7 mRNA CTD PMID:20823114 NCBI chr 6:20,564,035...20,571,205
Ensembl chr 6:20,564,044...20,571,212 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression
decreases expression 		ISO
EXP 		27-hydroxycholesterol promotes the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; [[T0901317 co-treated with LG 100268] promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]] which results in increased abundance of Progesterone; [Bucladesine co-treated with ciglitazone] results in increased expression of STAR mRNA; [Bucladesine co-treated with ciglitazone] results in increased phosphorylation of STAR protein; [Bucladesine co-treated with LIPE protein] results in increased expression of and results in increased phosphorylation of STAR protein; [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone; [Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone; [ciglitazone co-treated with Bucladesine] promotes the reaction [JUN protein results in increased expression of STAR mRNA]; [T0901317 co-treated with LG 100268] promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; bisindolylmaleimide I inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR mRNA]; Bucladesine promotes the reaction [ciglitazone results in increased expression of STAR protein]; Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [[T0901317 results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [[T0901317 results in increased expression of STAR protein] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [LG 100268 promotes the reaction [T0901317 results in increased expression of STAR mRNA]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [[LG 100268 results in increased expression of STAR mRNA] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [[LG 100268 results in increased expression of STAR protein] which results in increased abundance of Progesterone]]; Bucladesine promotes the reaction [T0901317 promotes the reaction [LG 100268 results in increased expression of STAR mRNA]]; Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA; Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein; CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; ciglitazone promotes the reaction [Bucladesine results in increased expression of STAR protein]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]; lead acetate inhibits the reaction [Bucladesine results in increased expression of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; LIPE protein affects the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR0B1 protein inhibits the reaction [[Bucladesine results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR1H2 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR1H3 protein affects the reaction [CAY 10499 inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; NR4A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Probucol inhibits the reaction [STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased expression of ABCA1 mRNA]; STAR protein promotes the reaction [[Bucladesine co-treated with APOA1 protein] results in increased secretion of Cholesterol]; Tetradecanoylphorbol Acetate promotes the reaction [[Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; U 0126 inhibits the reaction [Bucladesine results in increased phosphorylation of STAR protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]]
[IMOL S-140 co-treated with triphenyl phosphate co-treated with tris(chloroethyl)phosphate co-treated with diphenylcresyl phosphate co-treated with tert-butylphenyl diphenyl phosphate co-treated with tri-xylenyl phosphate] inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; [tris(2-butoxyethyl) phosphate co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1,3-dichloro-2-propyl)phosphate co-treated with santicizer 148 co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; fluorene-9-bisphenol inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Organophosphates inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]
Bucladesine results in increased expression of STAR mRNA; Bucladesine results in increased expression of STAR protein
Bucladesine results in decreased expression of STAR mRNA
[Atrazine co-treated with Bucladesine] results in increased expression of STAR mRNA; Atrazine inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Quercetin inhibits the reaction [[Atrazine co-treated with Bucladesine] results in increased expression of STAR mRNA] 		CTD PMID:10964798 PMID:10993823 PMID:11213355 PMID:18755854 PMID:18787026 More... NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO STAT3 gene mutant form affects the reaction [IL22 protein inhibits the reaction [Bucladesine results in increased expression of G6PC1 protein]] CTD PMID:26064446 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stk38 serine/threonine kinase 38 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of STK38 mRNA CTD PMID:20823114 NCBI chr20:7,035,923...7,070,657
Ensembl chr20:7,035,933...7,069,711 		JBrowse link
G Sulf1 sulfatase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA CTD PMID:20823114 NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643 		JBrowse link
G Tagln transgelin multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TAGLN mRNA CTD PMID:20823114 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563 		JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TCEA1 mRNA CTD PMID:20823114 NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156 		JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TERT mRNA CTD PMID:20823114 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Testin testin gene decreases expression
multiple interactions 		EXP Bucladesine results in decreased expression of TESTIN mRNA
Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of TESTIN mRNA]; lonidamine inhibits the reaction [Bucladesine results in decreased expression of TESTIN mRNA] 		CTD PMID:11090432 NCBI chr17:3,829,012...3,864,995
Ensembl chr17:3,852,404...3,864,993 		JBrowse link
G Tfrc transferrin receptor decreases expression ISO Bucladesine results in decreased expression of TFRC protein CTD PMID:2989362 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tgfa transforming growth factor alpha decreases expression EXP Bucladesine results in decreased expression of TGFA mRNA CTD PMID:11843059 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA] CTD PMID:11576339 PMID:16430859 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate co-treated with Bucladesine] results in increased activity of TGM2 protein; [phenylsaligenin cyclic phosphate co-treated with Bucladesine] results in increased activity of TGM2 protein CTD PMID:32749514 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP Bucladesine results in increased expression of TH mRNA CTD PMID:19912776 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Bucladesine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein] CTD PMID:16716901 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tnc tenascin C multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TNC mRNA CTD PMID:20823114 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Bucladesine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Bucladesine inhibits the reaction [Dopamine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]]; Bucladesine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
Bucladesine inhibits the reaction [Zymosan results in increased expression of TNF protein] 		CTD PMID:11301049 PMID:12509806 PMID:12538815 PMID:15081246 PMID:20388727 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine co-treated with decitabine] results in increased expression of TP53 protein; [Estradiol co-treated with Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of TP53 protein CTD PMID:22534328 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpi1 triosephosphate isomerase 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TPI1 mRNA CTD PMID:20823114 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413 		JBrowse link
G Tpsg1 tryptase gamma 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of TPSG1 mRNA CTD PMID:20823114 NCBI chr10:14,889,838...14,895,605
Ensembl chr10:14,890,734...14,894,786 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of TXN mRNA CTD PMID:20823114 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Ube2d2b ubiquitin-conjugating enzyme E2D 2B multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of UBE2D4 mRNA CTD PMID:20823114 NCBI chr14:2,060,926...2,062,400
Ensembl chr14:2,048,235...2,063,764 		JBrowse link
G Ucp1 uncoupling protein 1 increases expression
multiple interactions 		EXP Bucladesine results in increased expression of UCP1 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of UCP1 mRNA] 		CTD PMID:12414803 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of UGCG mRNA CTD PMID:20823114 NCBI chr 5:78,828,006...78,860,725
Ensembl chr 5:78,828,006...78,860,417 		JBrowse link
G Usp12 ubiquitin specific peptidase 12 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA CTD PMID:20823114 NCBI chr12:13,423,625...13,477,547
Ensembl chr12:13,422,427...13,477,547 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Bucladesine results in increased expression of VEGFA mRNA CTD PMID:18591213 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin multiple interactions ISO [Azacitidine co-treated with Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VIM protein CTD PMID:20823114 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vps39 VPS39 subunit of HOPS complex multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of VPS39 mRNA CTD PMID:20823114 NCBI chr 3:127,721,076...127,758,658
Ensembl chr 3:127,721,076...127,758,768 		JBrowse link
G Wnt5a Wnt family member 5A multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WNT5A mRNA CTD PMID:20823114 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of WWTR1 mRNA CTD PMID:20823114 NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950 		JBrowse link
G Zbtb45 zinc finger and BTB domain containing 45 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZBTB45 mRNA CTD PMID:20823114 NCBI chr 1:82,707,633...82,712,926
Ensembl chr 1:82,707,634...82,710,277 		JBrowse link
G Zscan10 zinc finger and SCAN domain containing 10 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN10 mRNA CTD PMID:20823114 NCBI chr10:13,140,929...13,150,897
Ensembl chr10:13,140,929...13,150,897 		JBrowse link
G Zscan20 zinc finger and SCAN domain containing 20 multiple interactions ISO [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of ZSCAN20 mRNA CTD PMID:20823114 NCBI chr 5:146,214,023...146,240,678
Ensembl chr 5:146,215,082...146,240,777 		JBrowse link
chloramphenicol palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO chloramphenicol palmitate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
Dibutyl adipate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP di-n-butyl adipate binds to AR protein CTD PMID:14565775 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
Dimethyl adipate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression EXP dimethyladipate results in increased expression of HSPA1A protein CTD PMID:15690153 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
Dimethyl succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio2 iodothyronine deiodinase 2 increases activity EXP dimethyl succinate results in increased activity of DIO2 protein CTD PMID:17615150 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
Epolactaene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polb DNA polymerase beta multiple interactions EXP epolactaene binds to and results in decreased activity of POLB protein CTD PMID:15656580 NCBI chr16:76,081,903...76,105,174
Ensembl chr16:76,081,864...76,108,180 		JBrowse link
ethyl myristate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO ethyl myristate binds to and results in decreased activity of AR protein CTD PMID:27633901 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO ethyl myristate binds to and results in decreased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO ethyl myristate binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO ethyl myristate binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO ethyl myristate binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO ethyl myristate binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO ethyl myristate binds to and results in decreased activity of THRB protein CTD PMID:27633901 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
isopropyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of isopropyl palmitate analog CTD PMID:26820058 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
juvenile hormone III term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO juvenile hormone III binds to and results in increased activity of NR1H4 protein CTD PMID:15491415 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
lovastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression
decreases expression
multiple interactions 		ISO Lovastatin results in increased expression of ABCA1 mRNA
lovastatin decreases expression of ABCA1 mRNA in HepG2 cells
[Dietary Fats co-treated with Lovastatin] affects the expression of ABCA1 mRNA
Lovastatin results in decreased expression of ABCA1 mRNA 		CTD
RGD		 PMID:19260826 PMID:29852127 PMID:27765770 RGD:18936994 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity 		ISO Lovastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Lovastatin results in decreased activity of ABCB11 protein 		CTD PMID:23956101 PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
increases transport 		ISO Lovastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]
Lovastatin analog results in decreased activity of ABCB1 protein
ABCB1 protein results in increased transport of Lovastatin; ABCB1 protein results in increased transport of Lovastatin analog 		CTD PMID:15616150 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions 		ISO Lovastatin results in decreased activity of ABCC1 protein
[Lovastatin results in decreased activity of ABCC1 protein] which results in increased susceptibility to Antimony Sodium Gluconate; Doxorubicin inhibits the reaction [Lovastatin results in increased expression of ABCC1 mRNA] 		CTD PMID:18056276 PMID:22712078 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
decreases activity 		ISO
EXP 		ABCC2 protein binds to and results in increased uptake of Lovastatin analog; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
Lovastatin results in increased expression of ABCC2 mRNA
Lovastatin analog results in decreased activity of ABCC2 protein
ABCC2 protein binds to and results in increased uptake of Lovastatin analog; Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Lovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]; Lovastatin promotes the reaction [Cisplatin results in decreased expression of ABCC2 mRNA] 		CTD PMID:15616150 PMID:23562342 PMID:26739623 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression
multiple interactions 		ISO Lovastatin affects the expression of ABCG5 mRNA
[Dietary Fats co-treated with Lovastatin] affects the expression of ABCG5 mRNA 		CTD PMID:27208389 PMID:29852127 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 affects expression ISO Lovastatin affects the expression of ABCG8 mRNA CTD PMID:27208389 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of ACACA mRNA CTD PMID:29852127 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of ACOX1 mRNA CTD PMID:29852127 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of ACSS2 mRNA CTD PMID:29852127 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression 		ISO Lovastatin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Lovastatin results in decreased expression of ACTA2 protein 		CTD PMID:22129737 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Actb actin, beta decreases expression
increases expression 		ISO Lovastatin results in decreased expression of ACTB mRNA
Lovastatin results in increased expression of ACTB mRNA 		CTD PMID:20493250 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Actr3 actin related protein 3 increases expression ISO Lovastatin results in increased expression of ACTR3 mRNA CTD PMID:20493250 NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711 		JBrowse link
G Adam10 ADAM metallopeptidase domain 10 increases expression
multiple interactions 		EXP
ISO 		Lovastatin results in increased expression of ADAM10 protein
[Lovastatin co-treated with APP protein] results in increased expression of ADAM10 protein 		CTD PMID:29341888 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing affects expression
multiple interactions 		ISO Lovastatin affects the expression of ADIPOQ mRNA
[Dietary Fats co-treated with Lovastatin] affects the expression of ADIPOQ mRNA 		CTD PMID:27208389 PMID:29852127 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO Lovastatin results in decreased expression of AHCY mRNA CTD PMID:20493250 NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587 		JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases response to substance ISO AKAP7 SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr 1:21,906,503...22,168,663
Ensembl chr 1:21,906,676...22,037,090 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation 		ISO
EXP 		Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in decreased expression of AKT1 protein]
Lovastatin results in decreased phosphorylation of AKT1 protein 		CTD PMID:16425225 PMID:17472962 PMID:19760159 PMID:20578043 PMID:35734936 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions EXP Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased activity of ALOX15 protein] CTD PMID:35734936 NCBI chr10:55,559,060...55,567,535
Ensembl chr10:55,559,061...55,567,723 		JBrowse link
G Ank2 ankyrin 2 decreases response to substance ISO ANK2 SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:218,052,555...218,537,259 		JBrowse link
G Anxa4 annexin A4 decreases expression ISO Lovastatin results in decreased expression of ANXA4 mRNA CTD PMID:20493250 NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513 		JBrowse link
G Anxa5 annexin A5 decreases expression ISO Lovastatin results in decreased expression of ANXA5 mRNA CTD PMID:20493250 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO [Lovastatin co-treated with Niacin] results in increased expression of APOA1 protein; [Niacin co-treated with Lovastatin] results in increased expression of APOA1 protein CTD PMID:12633795 PMID:17319473 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apob apolipoprotein B multiple interactions
decreases secretion 		ISO [Niacin co-treated with Lovastatin] results in decreased expression of APOB protein
Lovastatin results in decreased secretion of APOB protein 		CTD PMID:11728391 PMID:12633795 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoe apolipoprotein E affects expression
multiple interactions 		ISO Lovastatin affects the expression of APOE mRNA
[Dietary Fats co-treated with Lovastatin] affects the expression of APOE mRNA 		CTD PMID:27208389 PMID:29852127 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G App amyloid beta precursor protein multiple interactions
increases cleavage
increases secretion 		EXP
ISO 		2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lovastatin results in increased secretion of APP protein modified form]; TAPI-2 inhibits the reaction [Lovastatin results in increased secretion of APP protein modified form]; U 0126 inhibits the reaction [Lovastatin results in increased secretion of APP protein]
[APP protein co-treated with Lovastatin] results in increased secretion of APP protein; [Lovastatin co-treated with APP protein] results in decreased expression of BACE1 protein; [Lovastatin co-treated with APP protein] results in increased expression of ADAM10 protein; [Lovastatin co-treated with APP protein] results in increased expression of BACE2 protein; [Lovastatin co-treated with APP protein] results in increased expression of CHRNA7 protein; [Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK1 protein; [Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK3 protein; Lovastatin affects the reaction [[MAPK1 protein co-treated with APP protein] affects the expression of APP protein]; Lovastatin affects the reaction [[MAPK1 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; Lovastatin affects the reaction [[MAPK3 protein co-treated with APP protein] affects the expression of APP protein]; Lovastatin affects the reaction [[MAPK3 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; U 0126 inhibits the reaction [[APP protein co-treated with Lovastatin] results in increased secretion of APP protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased expression of CHRNA7 protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK3 protein]
Lovastatin results in increased cleavage of APP protein
Lovastatin results in increased secretion of APP protein; Lovastatin results in increased secretion of APP protein modified form 		CTD PMID:19741129 PMID:29341888 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Lovastatin results in increased expression of ARHGDIA mRNA CTD PMID:20493250 NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 increases expression ISO Lovastatin results in increased expression of ASIC3 mRNA CTD PMID:38432573 NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:11,652,946...11,657,367 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of ATM protein modified form] CTD PMID:26739623 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atr ATR serine/threonine kinase multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of ATR protein modified form] CTD PMID:26739623 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718 		JBrowse link
G Bace1 beta-secretase 1 decreases expression
multiple interactions 		EXP
ISO 		Lovastatin results in decreased expression of BACE1 protein
[Lovastatin co-treated with APP protein] results in decreased expression of BACE1 protein 		CTD PMID:29341888 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918 		JBrowse link
G Bace2 beta-secretase 2 multiple interactions
increases expression 		ISO
EXP 		[Lovastatin co-treated with APP protein] results in increased expression of BACE2 protein
Lovastatin results in increased expression of BACE2 protein 		CTD PMID:29341888 NCBI chr11:50,176,852...50,258,948
Ensembl chr11:50,176,621...50,259,008 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
affects localization 		ISO
EXP 		Lovastatin results in increased expression of BAX protein
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of BAX protein]; Lovastatin promotes the reaction [Cisplatin results in increased expression of BAX mRNA]
Lovastatin affects the localization of BAX protein 		CTD PMID:10473109 PMID:15180944 PMID:26739623 PMID:35734936 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member increases cleavage
multiple interactions 		EXP Lovastatin results in increased cleavage of BCAR1 protein
Mevalonic Acid inhibits the reaction [Lovastatin results in increased cleavage of BCAR1 protein] 		CTD PMID:16367743 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO
EXP 		Lovastatin results in decreased expression of BCL2 protein
Lovastatin inhibits the reaction [Cholesterol, Dietary results in decreased expression of BCL2 protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in decreased expression of BCL2 protein] 		CTD PMID:10473109 PMID:11178870 PMID:12094262 PMID:35734936 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions 		EXP Lovastatin results in decreased expression of BCL2L1 protein
Mevalonic Acid inhibits the reaction [Lovastatin results in decreased expression of BCL2L1 protein] 		CTD PMID:11178870 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression 		ISO
EXP 		pyrazolanthrone inhibits the reaction [Lovastatin results in increased expression of BCL2L11 protein]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of BCL2L11 protein] 		CTD PMID:18766339 PMID:35734936 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased expression of BDNF protein] CTD PMID:24718106 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression 		ISO farnesyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in decreased expression of BIRC5 protein] CTD PMID:17472962 PMID:18815881 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of BRCA2 mRNA] CTD PMID:22712078 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194 		JBrowse link
G C1qbp complement C1q binding protein increases expression ISO Lovastatin results in increased expression of C1QBP mRNA CTD PMID:20493250 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235 		JBrowse link
G Calr calreticulin increases expression ISO Lovastatin results in increased expression of CALR mRNA CTD PMID:20493250 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of CAMK2B protein] CTD PMID:24718106 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Casp2 caspase 2 increases activity
multiple interactions 		ISO Lovastatin results in increased activity of CASP2 protein
Lovastatin promotes the reaction [RHOB protein binds to CASP2 protein] 		CTD PMID:12933658 PMID:16234849 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
decreases expression 		ISO
EXP 		farnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]
Lovastatin analog results in increased cleavage of CASP3 protein
Lovastatin results in increased activity of CASP3 protein
Lovastatin results in decreased expression of CASP3 mRNA
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of CASP3 protein]; Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein; Mevalonic Acid inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein] 		CTD PMID:11720884 PMID:12933658 PMID:15180944 PMID:16367743 PMID:18034278 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp6 caspase 6 increases activity ISO Lovastatin results in increased activity of CASP6 protein CTD PMID:11720884 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp8 caspase 8 increases activity ISO Lovastatin results in increased activity of CASP8 protein CTD PMID:15180944 PMID:15705602 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions 		ISO
EXP 		Lovastatin results in increased activity of CASP9 protein
Lovastatin inhibits the reaction [Cholesterol, Dietary results in decreased expression of CASP9 protein] 		CTD PMID:12933658 PMID:15180944 PMID:15705602 PMID:35734936 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions EXP Lovastatin inhibits the reaction [Cholesterol, Dietary results in decreased activity of CAT protein] CTD PMID:35734936 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA]; Lovastatin inhibits the reaction [Epirubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 PMID:28710503 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
increases expression 		ISO
EXP 		Lovastatin results in decreased expression of CCND1 protein
Lovastatin results in increased expression of CCND1 mRNA; Lovastatin results in increased expression of CCND1 protein 		CTD PMID:18034278 PMID:20578043 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Lovastatin results in decreased expression of CCND3 protein CTD PMID:10502407 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression ISO Lovastatin results in increased expression of CCT5 mRNA CTD PMID:20493250 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression ISO Lovastatin results in increased expression of CCT6A mRNA CTD PMID:20493250 NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 decreases expression ISO Lovastatin results in decreased expression of CCT8 mRNA CTD PMID:20493250 NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Lovastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA] CTD PMID:17507688 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd44 CD44 molecule decreases expression ISO Lovastatin results in decreased expression of CD44 mRNA; Lovastatin results in decreased expression of CD44 protein CTD PMID:21199873 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cdc42 cell division cycle 42 increases expression
decreases expression 		ISO Lovastatin results in increased expression of CDC42 protein
Lovastatin results in decreased expression of CDC42 mRNA 		CTD PMID:18766339 PMID:20493250 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity ISO Lovastatin results in decreased activity of CDK2 protein CTD PMID:10502407 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP Lovastatin results in decreased expression of CDK4 mRNA; Lovastatin results in decreased expression of CDK4 protein CTD PMID:20578043 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases cleavage EXP Lovastatin results in decreased cleavage of CDK5 protein CTD PMID:19741129 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions 		ISO Lovastatin results in increased expression of CDKN1A protein
Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] 		CTD PMID:18034278 PMID:22712078 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP
ISO 		Lovastatin results in increased expression of CDKN1B mRNA; Lovastatin results in increased expression of CDKN1B protein CTD PMID:9848777 PMID:10502407 PMID:15118409 PMID:18034278 PMID:20578043 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of CDKN3 protein modified form] CTD PMID:26739623 NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722 		JBrowse link
G Cenpf centromere protein F increases expression
multiple interactions 		ISO Lovastatin results in increased expression of CENPF protein
Lovastatin promotes the reaction [Paclitaxel results in increased expression of CENPF protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of CENPF protein] 		CTD PMID:12467231 NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886 		JBrowse link
G Cfl1 cofilin 1 decreases phosphorylation EXP Lovastatin results in decreased phosphorylation of CFL1 protein CTD PMID:20578043 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO
EXP 		Lovastatin inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK1 protein]; Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of CHEK1 protein]
Lovastatin inhibits the reaction [Cisplatin results in increased expression of CHEK1 protein modified form] 		CTD PMID:17088865 PMID:21356574 PMID:26739623 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of CHEK2 protein modified form] CTD PMID:26739623 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions
increases expression 		ISO
EXP 		[Lovastatin co-treated with APP protein] results in increased expression of CHRNA7 protein; Lovastatin affects the reaction [[MAPK1 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; Lovastatin affects the reaction [[MAPK3 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased expression of CHRNA7 protein]
Lovastatin results in increased expression of CHRNA7 mRNA; Lovastatin results in increased expression of CHRNA7 protein
U 0126 inhibits the reaction [Lovastatin results in increased expression of CHRNA7 protein] 		CTD PMID:29341888 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858 		JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Lovastatin results in decreased expression of CLIC1 mRNA CTD PMID:20493250 NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression ISO Lovastatin results in increased expression of COX5A mRNA CTD PMID:20493250 NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279 		JBrowse link
G Cp ceruloplasmin multiple interactions EXP Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of CP protein] CTD PMID:35734936 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of CREB1 protein] CTD PMID:24718106 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein increases expression ISO Lovastatin results in increased expression of CRK mRNA CTD PMID:20493250 NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988 		JBrowse link
G Crp C-reactive protein multiple interactions EXP Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of CRP protein] CTD PMID:35734936 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Ctnnb1 catenin beta 1 decreases degradation
increases expression
multiple interactions 		EXP
ISO 		Lovastatin results in decreased degradation of CTNNB1 protein
Lovastatin results in increased expression of CTNNB1 mRNA
Lovastatin affects the localization of and results in increased expression of CTNNB1 protein 		CTD PMID:17234346 PMID:19741129 PMID:24742230 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression 		ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CYP1A1 mRNA]; Lovastatin results in increased expression of and results in increased activity of CYP1A1 protein
Lovastatin results in increased expression of CYP1A1 mRNA 		CTD PMID:1311272 PMID:22712078 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Lovastatin results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Lovastatin results in decreased activity of CYP2C8 protein CTD PMID:15601807
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression 		ISO [Lovastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
Lovastatin results in increased expression of CYP3A4 mRNA 		CTD PMID:12505310 PMID:17041008 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Dctn2 dynactin subunit 2 decreases expression ISO Lovastatin results in decreased expression of DCTN2 mRNA CTD PMID:20493250 NCBI chr 7:64,977,338...64,992,875
Ensembl chr 7:64,977,363...64,992,873 		JBrowse link
G Ddt D-dopachrome tautomerase decreases expression ISO Lovastatin results in decreased expression of DDT mRNA CTD PMID:20493250 NCBI chr20:12,883,025...12,886,121 JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of DLG3 protein] CTD PMID:24718106 NCBI chr  X:69,899,694...69,951,928
Ensembl chr  X:69,900,003...69,950,696 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression ISO Lovastatin results in decreased expression of DLST mRNA CTD PMID:20493250 NCBI chr 6:110,489,576...110,512,841
Ensembl chr 6:110,489,392...110,514,357 		JBrowse link
G Dock7 dedicator of cytokinesis 7 increases expression ISO Lovastatin results in increased expression of DOCK7 mRNA CTD PMID:20493250 NCBI chr 5:118,714,863...118,898,362
Ensembl chr 5:118,714,863...118,898,335 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 increases expression ISO Lovastatin results in increased expression of DPYSL2 mRNA CTD PMID:20493250 NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065 		JBrowse link
G Dstn destrin, actin depolymerizing factor decreases expression ISO Lovastatin results in decreased expression of DSTN mRNA CTD PMID:20493250 NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769 		JBrowse link
G Eaf2 ELL associated factor 2 decreases response to substance ISO EAF2 SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression ISO Lovastatin results in decreased expression of EEF2 mRNA CTD PMID:20493250 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO Lovastatin inhibits the reaction [EGF protein promotes the reaction [EGFR protein results in increased phosphorylation of EGFR protein]]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of AKT1 protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of RAF1 protein] CTD PMID:12942316 PMID:19760159 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO Lovastatin inhibits the reaction [EGF protein promotes the reaction [EGFR protein results in increased phosphorylation of EGFR protein]]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:12942316 PMID:19760159 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I decreases expression ISO Lovastatin results in decreased expression of EIF3I mRNA CTD PMID:20493250 NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression
multiple interactions 		EXP Lovastatin results in increased expression of ERCC1 mRNA
Lovastatin promotes the reaction [Cisplatin results in increased expression of ERCC1 mRNA] 		CTD PMID:26739623 NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120 		JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions
increases expression 		EXP Lovastatin promotes the reaction [Cisplatin results in increased expression of ERCC5 mRNA]
Lovastatin results in increased expression of ERCC5 mRNA 		CTD PMID:26739623 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases expression EXP Lovastatin results in increased expression of ERCC6 mRNA CTD PMID:26739623 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,771,581...7,841,895 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 decreases expression ISO Lovastatin results in decreased expression of ERP29 mRNA CTD PMID:20493250 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010 		JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of FADS2 mRNA CTD PMID:29852127 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO
EXP 		Lovastatin inhibits the reaction [Doxorubicin results in increased expression of FAS mRNA]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of FAS protein] 		CTD PMID:17088865 PMID:35734936 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA] CTD PMID:17088865 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Lovastatin results in increased expression of FASN mRNA CTD PMID:11728391 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fbxo32 F-box protein 32 multiple interactions
increases expression 		ISO geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of FBXO32 protein]; Lovastatin promotes the reaction [Fenofibrate results in increased expression of FBXO32 protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of FBXO32 mRNA]; Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of FBXO32 protein]
Lovastatin results in increased expression of FBXO32 mRNA; Lovastatin results in increased expression of FBXO32 protein 		CTD PMID:19406843 PMID:33408297 NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases activity ISO Lovastatin results in increased activity of FDFT1 protein CTD PMID:8517861 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168 		JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO
EXP 		[Dietary Fats co-treated with Lovastatin] affects the expression of FDPS mRNA
[Cholestyramine Resin co-treated with Lovastatin] results in increased expression of FDPS mRNA; Mevalonic Acid inhibits the reaction [[Cholestyramine Resin co-treated with Lovastatin] results in increased expression of FDPS mRNA] 		CTD PMID:3670308 PMID:29852127 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Flot1 flotillin 1 decreases expression ISO Lovastatin results in decreased expression of FLOT1 protein CTD PMID:12628479 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
decreases expression 		EXP
ISO 		Lovastatin affects the expression of FOS protein
Lovastatin inhibits the reaction [Doxorubicin results in increased expression of FOS mRNA]
Lovastatin results in decreased expression of FOS 		CTD PMID:10412747 PMID:12392621 PMID:22712078 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Lovastatin inhibits the reaction [benserazide, levodopa drug combination results in increased expression of FOSB protein] CTD PMID:18434508 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases phosphorylation 		ISO Lovastatin promotes the reaction [Fenofibrate results in increased expression of FOXO1 protein]
Lovastatin results in decreased phosphorylation of FOXO1 protein 		CTD PMID:33034787 PMID:33408297 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 decreases expression ISO Lovastatin results in decreased expression of FSCN1 mRNA CTD PMID:20493250 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases expression ISO Lovastatin results in increased expression of G3BP1 mRNA CTD PMID:20493250 NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of G6PD mRNA CTD PMID:29852127 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gale UDP-galactose-4-epimerase decreases expression ISO Lovastatin results in decreased expression of GALE mRNA CTD PMID:20493250 NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:153,478,325...153,481,922 		JBrowse link
G Gap43 growth associated protein 43 increases expression ISO Lovastatin results in increased expression of GAP43 protein CTD PMID:20694854 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Gdi2 GDP dissociation inhibitor 2 increases expression ISO Lovastatin results in increased expression of GDI2 mRNA CTD PMID:20493250 NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147 		JBrowse link
G Gk glycerol kinase multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of GK mRNA CTD PMID:29852127 NCBI chr  X:54,106,708...54,189,940
Ensembl chr  X:54,112,214...54,196,701 		JBrowse link
G Gmps guanine monophosphate synthase increases expression ISO Lovastatin results in increased expression of GMPS mRNA CTD PMID:20493250 NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of GPT protein; Lovastatin inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:29852127 PMID:30853469 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of GPX1 mRNA] CTD PMID:28710503 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of GRIN2B protein] CTD PMID:24718106 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
increases phosphorylation 		ISO
EXP 		Lovastatin results in decreased phosphorylation of GSK3B protein
Lovastatin results in increased phosphorylation of GSK3B protein 		CTD PMID:17234346 PMID:19741129 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO
EXP 		Lovastatin inhibits the reaction [Cisplatin results in increased phosphorylation of H2AX protein]
Lovastatin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form]
Lovastatin inhibits the reaction [Cisplatin results in increased expression of H2AX protein modified form]; Lovastatin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein modified form]; Lovastatin inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein] 		CTD PMID:21356574 PMID:22712078 PMID:26739623 PMID:28710503 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Has1 hyaluronan synthase 1 increases expression ISO Lovastatin results in increased expression of HAS1 mRNA; Lovastatin results in increased expression of HAS1 protein CTD PMID:38432573 NCBI chr 1:67,366,460...67,378,686
Ensembl chr 1:67,366,460...67,378,444 		JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO Lovastatin results in increased expression of HAS2 mRNA CTD PMID:38432573 NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535 		JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO Lovastatin results in increased expression of HDAC1 mRNA CTD PMID:20493250 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 increases expression ISO Lovastatin results in increased expression of HINT1 mRNA CTD PMID:20493250 NCBI chr10:39,490,225...39,493,970
Ensembl chr 4:93,430,926...93,431,642
Ensembl chr10:93,430,926...93,431,642 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
affects expression
decreases activity
increases expression 		ISO [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of farnesyl pyrophosphate; [Lovastatin results in decreased activity of HMGCR protein] which results in decreased abundance of geranylgeranyl pyrophosphate; Lovastatin inhibits the reaction [HMGCR protein results in increased abundance of geranyl diphosphate]
[Dietary Fats co-treated with Lovastatin] affects the expression of HMGCR mRNA
Lovastatin affects the expression of HMGCR mRNA
Lovastatin results in increased expression of HMGCR mRNA 		CTD PMID:8517861 PMID:8593127 PMID:17208200 PMID:19260826 PMID:19699819 More... NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of HMGCS1 mRNA CTD PMID:29852127 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		ISO Lovastatin results in increased expression of HMOX1 protein
Lovastatin inhibits the reaction [Doxorubicin results in increased expression of HMOX1 mRNA] 		CTD PMID:20594940 PMID:21910007 PMID:28710503 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression ISO Lovastatin results in increased expression of HNRNPAB mRNA CTD PMID:20493250 NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like decreases expression ISO Lovastatin results in decreased expression of HNRNPDL mRNA CTD PMID:20493250 NCBI chr14:9,861,716...9,867,945
Ensembl chr14:9,861,716...9,867,945 		JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F increases expression ISO Lovastatin results in increased expression of HNRNPF mRNA CTD PMID:20493250 NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression
increases expression 		ISO Lovastatin results in decreased expression of HNRNPK mRNA
Lovastatin results in increased expression of HNRNPK mRNA 		CTD PMID:20493250 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,268,385...6,280,565 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases prenylation
multiple interactions 		ISO Lovastatin results in decreased prenylation of HRAS protein
Lovastatin results in decreased prenylation of and results in decreased localization of HRAS protein 		CTD PMID:16156861 PMID:19360310 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression ISO Lovastatin results in decreased expression of HSP90AB1 mRNA CTD PMID:20493250 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression ISO Lovastatin results in increased expression of HSPA8 mRNA CTD PMID:20493250 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO Lovastatin results in increased expression of HSPD1 mRNA CTD PMID:20493250 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Lovastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA] CTD PMID:17507688 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO IGF1 protein results in decreased susceptibility to Lovastatin CTD PMID:9525472 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions EXP Lovastatin promotes the reaction [INS protein results in increased phosphorylation of IGF1R protein] CTD PMID:19741129 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL18 protein] CTD PMID:21430599 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; Lovastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein] CTD PMID:18809656 PMID:21430599 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il24 interleukin 24 multiple interactions ISO Lovastatin inhibits the reaction [Particulate Matter results in increased expression of IL24 protein]
Lovastatin inhibits the reaction [IL24 protein results in increased phosphorylation of STAT3 protein]; Lovastatin inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of IL24 protein]; Lovastatin inhibits the reaction [Particulate Matter results in increased expression of IL24 mRNA] 		CTD PMID:39029221 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP 		Lovastatin inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of IL6 protein] 		CTD PMID:28710503 PMID:35734936 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 multiple interactions EXP Lovastatin promotes the reaction [INS protein results in increased phosphorylation of IGF1R protein]; Lovastatin promotes the reaction [INS protein results in increased phosphorylation of INSR protein] CTD PMID:19741129 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Insig1 insulin induced gene 1 increases expression
multiple interactions 		ISO Lovastatin results in increased expression of INSIG1 mRNA
[Dietary Fats co-treated with Lovastatin] affects the expression of INSIG1 mRNA 		CTD PMID:19260826 PMID:29852127 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insig2 insulin induced gene 2 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of INSIG2 mRNA CTD PMID:29852127 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Insr insulin receptor multiple interactions EXP Lovastatin promotes the reaction [INS protein results in increased phosphorylation of INSR protein] CTD PMID:19741129 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Ipo5 importin 5 decreases expression ISO Lovastatin results in decreased expression of IPO5 mRNA CTD PMID:20493250 NCBI chr15:104,397,626...104,447,985
Ensembl chr15:104,397,276...104,447,985 		JBrowse link
G Irf4 interferon regulatory factor 4 decreases expression ISO Lovastatin results in decreased expression of IRF4 protein CTD PMID:33034787 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of IRS1 mRNA CTD PMID:29852127 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of IRS2 mRNA CTD PMID:29852127 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression ISO Lovastatin results in increased expression of ISYNA1 mRNA CTD PMID:20493250 NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Lovastatin results in decreased expression of ITGB1 protein CTD PMID:12405293 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
decreases expression 		EXP
ISO 		Lovastatin affects the expression of JUN protein
Lovastatin inhibits the reaction [Doxorubicin results in increased expression of JUN mRNA]
Lovastatin results in decreased expression of JUN 		CTD PMID:10412747 PMID:12392621 PMID:22712078 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects activity ISO Lovastatin affects the activity of KCNH2 protein CTD PMID:16278312 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 increases expression ISO Lovastatin results in increased expression of KCNJ11 mRNA CTD PMID:38432573 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases prenylation
increases expression
affects localization
increases activity 		ISO Lovastatin results in decreased prenylation of KRAS protein
Lovastatin results in increased expression of KRAS protein
Lovastatin affects the localization of KRAS protein
Lovastatin results in increased activity of KRAS protein 		CTD PMID:12106604 PMID:12907238 PMID:16156861 PMID:17005160 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Krt18 keratin 18 decreases expression ISO Lovastatin results in decreased expression of KRT18 mRNA CTD PMID:20493250 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848 		JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression ISO Lovastatin results in decreased expression of LASP1 mRNA CTD PMID:20493250 NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of LCN2 mRNA CTD PMID:30853469 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Ldha lactate dehydrogenase A increases expression ISO Lovastatin results in increased expression of LDHA protein CTD PMID:38432573 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
increases activity
increases expression 		ISO
EXP 		OSM protein promotes the reaction [Lovastatin results in increased expression of LDLR mRNA]
[Dietary Fats co-treated with Lovastatin] affects the expression of LDLR mRNA
[Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA; Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased expression of LDLR mRNA]
Lovastatin results in increased activity of LDLR protein 		CTD PMID:8593127 PMID:11728391 PMID:12524230 PMID:20578043 PMID:29852127 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 affects localization ISO Lovastatin affects the localization of LEF1 protein CTD PMID:17234346 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Lipc lipase C, hepatic type affects expression ISO Lovastatin affects the expression of LIPC mRNA CTD PMID:27208389 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lmnb1 lamin B1 decreases farnesylation
increases degradation
affects localization 		ISO Lovastatin results in decreased farnesylation of LMNB1 protein
Lovastatin results in increased degradation of LMNB1 protein
Lovastatin affects the localization of LMNB1 protein 		CTD PMID:10203554 PMID:11720884 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283 		JBrowse link
G Lpin2 lipin 2 decreases response to substance ISO LPIN2 SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr 9:118,529,988...118,604,796
Ensembl chr 9:118,529,943...118,604,796 		JBrowse link
G Lpl lipoprotein lipase affects expression
multiple interactions 		ISO Lovastatin affects the expression of LPL mRNA
[Dietary Fats co-treated with Lovastatin] affects the expression of LPL mRNA 		CTD PMID:27208389 PMID:29852127 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO Lovastatin results in increased expression of LRP5 mRNA CTD PMID:24742230 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
increases phosphorylation
decreases activity
decreases phosphorylation 		EXP
ISO 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK1 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK1 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK1 protein]; Lovastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Lovastatin results in increased phosphorylation of MAPK1 protein]
Lovastatin results in increased expression of MAPK1 protein
Lovastatin results in decreased activity of MAPK1 protein
[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK1 protein; Lovastatin affects the reaction [[MAPK1 protein co-treated with APP protein] affects the expression of APP protein]; Lovastatin affects the reaction [[MAPK1 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK1 protein] 		CTD PMID:12213976 PMID:16952276 PMID:19360310 PMID:19760159 PMID:20578043 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO Lovastatin results in increased expression of MAPK14 protein CTD PMID:38432573 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
increases phosphorylation
decreases activity
decreases phosphorylation 		ISO
EXP 		[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK3 protein; Lovastatin affects the reaction [[MAPK3 protein co-treated with APP protein] affects the expression of APP protein]; Lovastatin affects the reaction [[MAPK3 protein co-treated with APP protein] affects the expression of CHRNA7 protein]; Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [[Lovastatin co-treated with APP protein] results in increased phosphorylation of MAPK3 protein]
Lovastatin results in increased expression of MAPK3 protein
Lovastatin results in increased phosphorylation of MAPK3 protein
Lovastatin results in decreased activity of MAPK3 protein
Lovastatin results in decreased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK3 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK3 protein]; Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in decreased phosphorylation of MAPK3 protein]; Lovastatin inhibits the reaction [benserazide, levodopa drug combination results in increased phosphorylation of MAPK3 protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in decreased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Lovastatin results in increased phosphorylation of MAPK3 protein] 		CTD PMID:16952276 PMID:18434508 PMID:19360310 PMID:19760159 PMID:20578043 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK8 protein modified form] CTD PMID:26739623 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP Lovastatin inhibits the reaction [Cisplatin results in increased expression of MAPK9 protein modified form] CTD PMID:26739623 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mbp myelin basic protein multiple interactions
increases expression 		EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [Lovastatin results in increased expression of MBP mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of MBP mRNA]; PPARG protein affects the reaction [Lovastatin results in increased expression of MBP mRNA]; PTEN protein affects the reaction [Lovastatin results in increased expression of MBP mRNA] CTD PMID:20578043 NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of MFN2 mRNA] CTD PMID:28710503 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Mir133b microRNA 133b multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of MIR133B mRNA CTD PMID:30853469 NCBI chr 9:30,594,582...30,594,665
Ensembl chr 9:30,594,582...30,594,665 		JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of MIR206 mRNA CTD PMID:30853469 NCBI chr 9:30,590,697...30,590,780
Ensembl chr 9:30,590,697...30,590,780 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Lovastatin results in decreased expression of MMP2 protein CTD PMID:19360310 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of MMP3 mRNA] CTD PMID:28710503 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Lovastatin results in decreased expression of MMP9 protein CTD PMID:19360310 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of MPO protein] CTD PMID:35734936 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mstn myostatin increases expression ISO Lovastatin results in increased expression of MSTN protein CTD PMID:33034787 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:55,944,513...55,950,913 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Doxorubicin inhibits the reaction [Lovastatin results in increased expression of NFE2L2 mRNA]; Lovastatin inhibits the reaction [Doxorubicin results in increased expression of NFE2L2 mRNA] CTD PMID:22712078 PMID:28710503 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nmral1 NmrA like redox sensor 1 increases expression ISO Lovastatin results in increased expression of NMRAL1 mRNA CTD PMID:20493250 NCBI chr10:11,348,080...11,356,621
Ensembl chr10:11,348,213...11,356,620 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP 		Lovastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of NOS2 protein] 		CTD PMID:18809656 PMID:35734936 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of NPPA mRNA] CTD PMID:28710503 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Lovastatin results in increased expression of NQO1 mRNA CTD PMID:1311272 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Lovastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:17041008 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nras NRAS proto-oncogene, GTPase decreases prenylation ISO Lovastatin results in decreased prenylation of NRAS protein CTD PMID:16156861 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543 		JBrowse link
G Nucb1 nucleobindin 1 increases expression ISO Lovastatin results in increased expression of NUCB1 mRNA CTD PMID:20493250 NCBI chr 1:105,104,793...105,135,730
Ensembl chr 1:105,104,793...105,135,837 		JBrowse link
G Oat ornithine aminotransferase decreases expression ISO Lovastatin results in decreased expression of OAT mRNA CTD PMID:20493250 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Osm oncostatin M multiple interactions ISO OSM protein promotes the reaction [Lovastatin results in increased expression of LDLR mRNA] CTD PMID:12524230 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression ISO Lovastatin results in increased expression of PA2G4 mRNA CTD PMID:20493250 NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Lovastatin analog results in increased cleavage of PARP1 protein CTD PMID:26863638 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parvb parvin, beta decreases response to substance ISO PARVB SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr 7:117,240,238...117,325,744
Ensembl chr 7:117,240,029...117,325,748 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of PCK1 mRNA CTD PMID:29852127 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression EXP Lovastatin results in decreased expression of PDGFRA mRNA CTD PMID:20578043 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression
increases expression 		ISO Lovastatin results in decreased expression of PDIA3 mRNA
Lovastatin results in increased expression of PDIA3 mRNA 		CTD PMID:20493250 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Lovastatin results in decreased expression of PDIA4 mRNA CTD PMID:20493250 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression
increases expression 		ISO Lovastatin results in decreased expression of PGAM1 mRNA
Lovastatin results in increased expression of PGAM1 mRNA 		CTD PMID:20493250 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203 		JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO Lovastatin results in decreased expression of PKM mRNA CTD PMID:20493250 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression EXP Lovastatin results in increased expression of PLA2G4A mRNA CTD PMID:20578043 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Plat plasminogen activator, tissue type multiple interactions
increases secretion
increases expression 		EXP
ISO 		geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PLAT protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of PLAT protein]
Lovastatin results in increased secretion of PLAT protein 		CTD PMID:10412747 PMID:12405293 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plau plasminogen activator, urokinase decreases secretion ISO Lovastatin results in decreased secretion of PLAU protein CTD PMID:12405293 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Pon3 paraoxonase 3 increases hydrolysis
increases metabolic processing
multiple interactions 		ISO PON3 protein results in increased hydrolysis of Lovastatin
PON3 protein results in increased metabolism of Lovastatin
7-ketocholesterol inhibits the reaction [PON3 protein results in increased metabolism of Lovastatin]; Phosphatidylcholines inhibits the reaction [PON3 protein results in increased metabolism of Lovastatin] 		CTD PMID:12615656 PMID:15772423 NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
affects localization
increases expression 		ISO
EXP 		2-chloro-5-nitrobenzanilide inhibits the reaction [Lovastatin analog affects the localization of PPARG protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Lovastatin analog affects the localization of PPARG protein]; PPARG protein affects the reaction [Lovastatin results in increased expression of PTEN protein]
geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PPARG mRNA]; Lovastatin results in increased expression of and affects the localization of PPARG protein; Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of PPARG mRNA]; PPARG protein affects the reaction [Lovastatin results in increased expression of MBP mRNA]; PPARG protein affects the reaction [Lovastatin results in increased expression of SOX10 mRNA]
[Dietary Fats co-treated with Lovastatin] affects the expression of PPARG mRNA; PPARG affects the reaction [Lovastatin results in increased expression of PTEN protein] 		CTD PMID:16425225 PMID:20578043 PMID:26863638 PMID:29852127 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of PPARGC1A mRNA] CTD PMID:28710503 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO Lovastatin results in decreased expression of PPP1CA mRNA CTD PMID:20493250 NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:210,914,567...210,918,193 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression ISO Lovastatin results in increased expression of PPP2R1A mRNA CTD PMID:20493250 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242 		JBrowse link
G Prg4 proteoglycan 4 increases expression ISO Lovastatin results in increased expression of PRG4 mRNA; Lovastatin results in increased expression of PRG4 protein CTD PMID:38432573 NCBI chr13:65,037,363...65,054,764
Ensembl chr13:65,037,363...65,054,508 		JBrowse link
G Prkca protein kinase C, alpha increases expression ISO Lovastatin results in increased expression of PRKCA protein CTD PMID:38432573 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
increases cleavage 		EXP benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Lovastatin results in increased cleavage of PRKCD protein]; Mevalonic Acid inhibits the reaction [Lovastatin results in increased cleavage of PRKCD protein] CTD PMID:16367743 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression ISO Lovastatin results in decreased expression of PSMA3 mRNA CTD PMID:20493250 NCBI chr 6:95,219,714...95,239,745
Ensembl chr 6:95,219,629...95,241,032 		JBrowse link
G Psma6 proteasome 20S subunit alpha 6 decreases expression ISO Lovastatin results in decreased expression of PSMA6 mRNA CTD PMID:20493250 NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 decreases expression ISO Lovastatin results in decreased expression of PSMC2 mRNA CTD PMID:20493250 NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
increases expression 		ISO
EXP 		Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein]; PPARG protein affects the reaction [Lovastatin results in increased expression of PTEN protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of PTEN mRNA]; Lovastatin results in increased expression of and results in increased phosphorylation of PTEN protein; PTEN protein affects the reaction [Lovastatin results in increased expression of MBP mRNA]; PTEN protein affects the reaction [Lovastatin results in increased expression of SOX10 mRNA]
PPARG affects the reaction [Lovastatin results in increased expression of PTEN protein] 		CTD PMID:16425225 PMID:20578043 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
increases expression
multiple interactions 		ISO
EXP 		Lovastatin results in decreased expression of PTGS2 protein
Lovastatin analog results in increased expression of PTGS2 mRNA; Lovastatin analog results in increased expression of PTGS2 protein
Mevalonic Acid affects the reaction [Lovastatin analog results in increased expression of PTGS2 protein]
Lovastatin results in increased expression of PTGS2 mRNA; Lovastatin results in increased expression of PTGS2 protein 		CTD PMID:20578043 PMID:21910007 PMID:26863638 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rab1a RAB1A, member RAS oncogene family decreases expression ISO Lovastatin results in decreased expression of RAB1A mRNA CTD PMID:20493250 NCBI chr14:98,623,582...98,648,766
Ensembl chr14:98,623,635...98,661,582 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
affects localization
decreases activity
increases expression 		ISO geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RAC1 protein]; Mevalonic Acid inhibits the reaction [Lovastatin affects the localization of RAC1 protein]
Lovastatin results in decreased activity of RAC1 protein
Lovastatin results in increased expression of RAC1 protein 		CTD PMID:12933658 PMID:18766339 PMID:19360310 PMID:21356574 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
decreases activity 		ISO Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of RAF1 protein]
Lovastatin results in decreased activity of RAF1 protein 		CTD PMID:19360310 PMID:19760159 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family increases expression ISO Lovastatin results in increased expression of RAP1A protein CTD PMID:12467231 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation EXP
ISO 		Lovastatin results in decreased phosphorylation of RB1 protein CTD PMID:9848777 PMID:10502407 PMID:15118409 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
decreases expression
decreases prenylation
affects localization 		ISO
EXP 		geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; Mevalonic Acid inhibits the reaction [Lovastatin affects the localization of RHOA protein]
Lovastatin results in decreased geranoylation of and affects the localization of RHOA protein
Lovastatin results in decreased expression of RHOA mRNA
Lovastatin results in decreased prenylation of RHOA protein
Farnesol inhibits the reaction [Lovastatin affects the localization of RHOA protein]; geranylgeraniol inhibits the reaction [Lovastatin affects the localization of RHOA protein] 		CTD PMID:9398081 PMID:11178870 PMID:12405293 PMID:12933658 PMID:16156861 More... NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rhob ras homolog family member B decreases prenylation
multiple interactions
increases expression 		ISO Lovastatin results in decreased prenylation of RHOB protein
Lovastatin promotes the reaction [RHOB protein binds to CASP2 protein]
Lovastatin results in increased expression of RHOB protein 		CTD PMID:12467231 PMID:16156861 PMID:16234849 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rpl27 ribosomal protein L27 increases expression ISO Lovastatin results in increased expression of RPL27 mRNA CTD PMID:20493250 NCBI chr10:86,875,758...86,879,457
Ensembl chr10:86,876,024...86,879,441 		JBrowse link
G Rpl9 ribosomal protein L9 increases expression ISO Lovastatin results in increased expression of RPL9 mRNA CTD PMID:20493250 NCBI chr14:43,247,536...43,250,784
Ensembl chr14:43,247,588...43,250,782
Ensembl chr 1:43,247,588...43,250,782 		JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 increases expression ISO Lovastatin results in increased expression of RPLP0 mRNA CTD PMID:20493250 NCBI chr12:46,715,121...46,718,390
Ensembl chr12:46,715,124...46,718,422 		JBrowse link
G Rpsa ribosomal protein SA increases expression ISO Lovastatin results in increased expression of RPSA mRNA CTD PMID:20493250 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 decreases expression ISO Lovastatin results in decreased expression of RUVBL2 mRNA CTD PMID:20493250 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of S100A8 mRNA CTD PMID:30853469 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO [Buthionine Sulfoximine co-treated with Lovastatin co-treated with Gemfibrozil] results in increased expression of S100A9 mRNA CTD PMID:30853469 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 decreases expression ISO Lovastatin results in decreased expression of SAE1 mRNA CTD PMID:20493250 NCBI chr 1:86,159,114...86,215,089
Ensembl chr 1:86,159,114...86,215,089 		JBrowse link
G Scap SREBF chaperone multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of SCAP mRNA CTD PMID:29852127 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
affects expression 		ISO [Chloroquine co-treated with Lovastatin] inhibits the reaction [SCARB1 protein results in increased abundance of Progesterone]
Lovastatin affects the expression of SCARB1 mRNA 		CTD PMID:20404351 PMID:27208389 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of SCD1 mRNA CTD PMID:29852127 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Sephs1 selenophosphate synthetase 1 increases expression ISO Lovastatin results in increased expression of SEPHS1 mRNA CTD PMID:20493250 NCBI chr17:78,263,725...78,296,132
Ensembl chr17:78,263,725...78,292,082 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 increases expression EXP Lovastatin results in increased expression of SLC31A1 mRNA CTD PMID:26739623 NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:80,830,389...80,859,809 		JBrowse link
G Sox10 SRY-box transcription factor 10 multiple interactions
increases expression 		EXP geranylgeranyl pyrophosphate inhibits the reaction [Lovastatin results in increased expression of SOX10 mRNA]; PPARG protein affects the reaction [Lovastatin results in increased expression of SOX10 mRNA]; PTEN protein affects the reaction [Lovastatin results in increased expression of SOX10 mRNA] CTD PMID:20578043 NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression 		ISO [Dietary Fats co-treated with Lovastatin] affects the expression of SREBF1 mRNA
Lovastatin results in increased expression of SREBF1 mRNA 		CTD PMID:29852127 PMID:32739440 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases localization
multiple interactions 		ISO
EXP 		Lovastatin results in increased localization of SREBF2 protein
[Dietary Fats co-treated with Lovastatin] affects the expression of SREBF2 mRNA
[Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein; Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein] 		CTD PMID:11728391 PMID:20578043 PMID:29852127 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Lovastatin inhibits the reaction [IL24 protein results in increased phosphorylation of STAT3 protein] CTD PMID:39029221 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Steap2 STEAP2 metalloreductase decreases response to substance ISO STEAP2 SNP results in decreased susceptibility to Lovastatin CTD PMID:21483694 NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:29,303,381...29,330,620 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Lovastatin results in decreased expression of STIP1 mRNA CTD PMID:20493250 NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 multiple interactions EXP Lovastatin inhibits the reaction [[Oxygen deficiency co-treated with Carbon Dioxide] results in increased expression of SYNGAP1 protein] CTD PMID:24718106 NCBI chr20:5,028,226...5,058,519
Ensembl chr20:5,026,707...5,057,751 		JBrowse link
G Tcp1 t-complex 1 increases expression ISO Lovastatin results in increased expression of TCP1 mRNA CTD PMID:20493250 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527 		JBrowse link
G Tg thyroglobulin increases secretion ISO Lovastatin results in increased secretion of TG protein CTD PMID:12843138 NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:100,307,349...100,314,539
Ensembl chr 7:100,307,349...100,314,539 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Lovastatin inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]; Lovastatin inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein] CTD PMID:22129737 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase increases expression
multiple interactions 		ISO Lovastatin results in increased expression of TH protein
Mevalonic Acid inhibits the reaction [Lovastatin results in increased expression of TH protein] 		CTD PMID:20694854 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thop1 thimet oligopeptidase 1 increases expression ISO Lovastatin results in increased expression of THOP1 mRNA CTD PMID:20493250 NCBI chr 7:9,283,617...9,295,957
Ensembl chr 7:9,283,617...9,295,957 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein; geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]]; lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]; Lovastatin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Lovastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Lovastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of TNF protein]
Lovastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of TNF protein] 		CTD PMID:18809656 PMID:21430599 PMID:22712078 PMID:35734936 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO Lovastatin results in increased expression of TNFRSF11B mRNA CTD PMID:24742230 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance ISO Lovastatin results in increased susceptibility to TNFSF10 protein CTD PMID:17928957 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Lovastatin results in decreased expression of TNFSF11 mRNA CTD PMID:24742230 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of TOP2A mRNA] CTD PMID:22712078 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		ISO
EXP 		Lovastatin inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; Lovastatin results in increased expression of and results in increased phosphorylation of TP53 protein
Lovastatin inhibits the reaction [Cisplatin results in increased expression of TP53 protein modified form]
Lovastatin results in increased expression of TP53 mRNA 		CTD PMID:17088865 PMID:21199873 PMID:26739623 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trim63 tripartite motif containing 63 multiple interactions ISO Lovastatin promotes the reaction [Fenofibrate results in increased expression of TRIM63 protein] CTD PMID:33408297 NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058 		JBrowse link
G Ttc7a tetratricopeptide repeat domain 7A multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of FSN mRNA CTD PMID:29852127 NCBI chr 6:12,912,822...13,015,374
Ensembl chr 6:12,905,527...13,015,374 		JBrowse link
G Tuba1a tubulin, alpha 1A increases expression ISO Lovastatin results in increased expression of TUBA1A mRNA CTD PMID:20493250 NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035 		JBrowse link
G Tuba1b tubulin, alpha 1B increases expression
decreases expression 		ISO Lovastatin results in increased expression of TUBA1B mRNA
Lovastatin results in decreased expression of TUBA1B mRNA 		CTD PMID:20493250 NCBI chr 7:131,969,606...131,972,587
Ensembl chr 7:131,968,770...131,996,035 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Lovastatin results in decreased expression of TUBB5 mRNA CTD PMID:20493250 NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726 		JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases expression ISO Lovastatin results in decreased expression of TUFM mRNA CTD PMID:20493250 NCBI chr 1:190,504,373...190,507,980
Ensembl chr 1:190,504,373...190,508,952 		JBrowse link
G U2af2 U2 small nuclear RNA auxiliary factor 2 increases expression ISO Lovastatin results in increased expression of U2AF2 mRNA CTD PMID:20493250 NCBI chr 1:77,789,752...77,807,307
Ensembl chr 1:77,789,752...77,807,413 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO [Dietary Fats co-treated with Lovastatin] affects the expression of UCP2 mRNA CTD PMID:29852127 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 decreases expression ISO Lovastatin results in decreased expression of USP5 mRNA CTD PMID:20493250 NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:159,305,938...159,320,956 		JBrowse link
G Vcp valosin-containing protein decreases expression
increases expression 		ISO Lovastatin results in decreased expression of VCP mRNA
Lovastatin results in increased expression of VCP mRNA 		CTD PMID:20493250 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions
increases expression 		ISO Lovastatin inhibits the reaction [Doxorubicin results in increased expression of WEE1 mRNA]
Lovastatin results in increased expression of WEE1 mRNA 		CTD PMID:22712078 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP Lovastatin results in increased expression of XIAP mRNA CTD PMID:26739623 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression EXP Lovastatin results in increased expression of XPA mRNA CTD PMID:26739623 NCBI chr 5:65,227,281...65,275,784
Ensembl chr 5:65,227,281...65,272,425 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon increases expression ISO Lovastatin results in increased expression of YWHAE mRNA CTD PMID:20493250 NCBI chr10:61,082,934...61,120,618
Ensembl chr10:61,106,716...61,114,291 		JBrowse link
methyl laurate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO lauric acid methyl ester binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of ESR2 protein; lauric acid methyl ester binds to and results in increased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO lauric acid methyl ester binds to and results in decreased activity of THRB protein CTD PMID:27633901 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
methyl linoleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO methyl linoleate inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
methyl oleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO methyl oleate binds to and results in increased activity of AHR protein CTD PMID:27633901 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO methyl oleate binds to and results in increased activity of ESR1 protein CTD PMID:27633901 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO methyl oleate binds to and results in increased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
Methyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO
EXP 		methyl palmitate binds to and results in increased activity of ESR1 protein
methyl palmitate inhibits the reaction [estradiol 3-benzoate results in increased expression of ESR1 protein] 		CTD PMID:27633901 PMID:32967526 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO methyl palmitate binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO methyl palmitate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL10 protein] CTD PMID:21575650 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP methyl palmitate inhibits the reaction [estradiol 3-benzoate results in increased expression of IL1B protein] CTD PMID:32967526 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO methyl palmitate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein] CTD PMID:21575650 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions 		ISO methyl palmitate results in decreased expression of RELA protein
methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein] 		CTD PMID:21575650 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
multiple interactions 		ISO methyl palmitate results in decreased secretion of TNF protein
methyl palmitate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] 		CTD PMID:21575650 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
O-butanoyl-L-carnitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance 		ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of butyrylcarnitine] CTD PMID:27469509 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
O-octanoylcarnitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crot carnitine O-octanoyltransferase increases chemical synthesis ISO CROT protein results in increased chemical synthesis of octanoylcarnitine CTD PMID:6838215 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064 		JBrowse link
p-nitrophenyl butyrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis 		ISO CES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl butyrate
CES1 protein results in increased hydrolysis of 4-nitrophenyl butyrate 		CTD PMID:11950785 PMID:16282638 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Ces3a carboxylesterase 3a increases hydrolysis ISO CES3 protein results in increased hydrolysis of 4-nitrophenyl butyrate CTD PMID:11950785 NCBI chr19:49,902,312...49,910,484 JBrowse link
paliperidone palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
multiple interactions
increases export
increases transport
affects response to substance
decreases activity 		ISO
EXP 		ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate; ABCB1 protein affects the abundance of Paliperidone Palmitate
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Paliperidone Palmitate]
ABCB1A protein results in increased transport of Paliperidone Palmitate
ABCB1A protein affects the susceptibility to Paliperidone Palmitate
Paliperidone Palmitate results in decreased activity of ABCB1 protein
Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]
ABCB1 protein results in increased transport of Paliperidone Palmitate 		CTD PMID:15502009 PMID:16118767 PMID:16810505 PMID:16936711 PMID:17541883 More... NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Paliperidone Palmitate CTD PMID:15502009 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Paliperidone Palmitate results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Paliperidone Palmitate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Paliperidone Palmitate results in increased expression of BDNF mRNA CTD PMID:21220416 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects abundance ISO CYP2D6 gene polymorphism affects the abundance of Paliperidone Palmitate; CYP2D6 protein affects the abundance of Paliperidone Palmitate CTD PMID:10639689 PMID:15089809 PMID:17541883 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding 		ISO
EXP 		Paliperidone Palmitate binds to and results in decreased activity of DRD2 protein
Paliperidone Palmitate binds to DRD2 protein 		CTD PMID:19713555 PMID:22437487 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions 		EXP Paliperidone Palmitate results in increased expression of FADS2 mRNA
[Paliperidone Palmitate results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, Unsaturated 		CTD PMID:21458237 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions 		ISO
EXP 		Paliperidone Palmitate binds to HTR2A protein
Paliperidone Palmitate binds to and results in decreased activity of HTR2A protein 		CTD PMID:7520908 PMID:19713555 PMID:22437487 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 PMID:20827463 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Paliperidone Palmitate results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Paliperidone Palmitate results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il24 interleukin 24 increases expression ISO Paliperidone Palmitate results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Paliperidone Palmitate results in decreased activity of KCNH2 protein CTD PMID:21394035 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Prl prolactin increases expression ISO Paliperidone Palmitate results in increased expression of PRL protein CTD PMID:17460786 PMID:19825908 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
phorbol 12,13-dibutanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam10 ADAM metallopeptidase domain 10 increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of ADAM10 protein CTD PMID:19476501 NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of ADAM9 protein CTD PMID:19476501 NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646 		JBrowse link
G App amyloid beta precursor protein increases secretion
multiple interactions 		ISO Phorbol 12,13-Dibutyrate results in increased secretion of APP protein modified form
Go 6976 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased secretion of APP protein modified form] 		CTD PMID:19476501 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions
affects localization 		ISO Go 6976 inhibits the reaction [Phorbol 12,13-Dibutyrate affects the localization of BACE1 protein] CTD PMID:19476501 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918 		JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions 		ISO Phorbol 12,13-Dibutyrate results in increased cleavage of CASP9 protein
rottlerin inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased cleavage of CASP9 protein] 		CTD PMID:12626342 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO Phorbol 12,13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]]
Phorbol 12,13-Dibutyrate results in increased expression of CDKN1A protein 		CTD PMID:15014036 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Phorbol 12,13-Dibutyrate inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Lead results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:9242432 PMID:10693946 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP Phorbol 12,13-Dibutyrate inhibits the reaction [N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno(1,2-c)pyrazole-3-carboxamide results in increased expression of HTR2A mRNA] CTD PMID:22791651 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Il12a interleukin 12A increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of IL12A mRNA CTD PMID:15516327 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of IL12B mRNA CTD PMID:15516327 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of IL23A mRNA CTD PMID:15516327 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Phorbol 12,13-Dibutyrate inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] CTD PMID:9242432 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Phorbol 12,13-Dibutyrate inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Phorbol 12,13-Dibutyrate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein] CTD PMID:16251475 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Phorbol 12,13-Dibutyrate inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Phorbol 12,13-Dibutyrate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein] CTD PMID:16251475 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases activity
multiple interactions 		ISO Phorbol 12,13-Dibutyrate results in increased activity of MMP9 protein
Quercetin inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased activity of MMP9 protein] 		CTD PMID:14593496 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Myl9 myosin light chain 9 multiple interactions
increases phosphorylation 		EXP 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased phosphorylation of MYL9 protein] CTD PMID:18986333 NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation EXP Phorbol 12,13-Dibutyrate results in increased phosphorylation of PPP1R12A protein CTD PMID:18986333 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157 		JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions
increases phosphorylation 		EXP 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased phosphorylation of PPP1R14A protein]; Ro 31-8220 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased phosphorylation of PPP1R14A protein] CTD PMID:18986333 NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147 		JBrowse link
G Prkca protein kinase C, alpha decreases expression
multiple interactions
increases expression 		ISO
EXP 		Phorbol 12,13-Dibutyrate results in decreased expression of PRKCA protein
Phorbol 12,13-Dibutyrate results in decreased expression of and affects the localization of PRKCA protein
Phorbol 12,13-Dibutyrate results in increased expression of PRKCA protein 		CTD PMID:9242432 PMID:12626342 PMID:17171646 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta increases expression
affects localization
affects binding 		ISO Phorbol 12,13-Dibutyrate results in increased expression of PRKCD protein
Phorbol 12,13-Dibutyrate affects the localization of PRKCD protein
Phorbol 12,13-Dibutyrate binds to PRKCD protein 		CTD PMID:8106444 PMID:12057904 PMID:12626342 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkce protein kinase C, epsilon affects binding ISO Phorbol 12,13-Dibutyrate binds to PRKCE protein CTD PMID:8106444 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkcz protein kinase C, zeta increases expression ISO Phorbol 12,13-Dibutyrate results in increased expression of PRKCZ protein CTD PMID:12626342 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Psen1 presenilin 1 multiple interactions
increases expression 		ISO Go 6976 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased expression of PSEN1 protein]
Phorbol 12,13-Dibutyrate results in increased expression of PSEN1 protein; Phorbol 12,13-Dibutyrate results in increased expression of PSEN1 protein modified form 		CTD PMID:19476501 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
G Rhoa ras homolog family member A increases expression
multiple interactions 		EXP Phorbol 12,13-Dibutyrate results in increased expression of RHOA protein modified form
Ro 31-8220 inhibits the reaction [Phorbol 12,13-Dibutyrate results in increased expression of RHOA protein modified form] 		CTD PMID:18986333 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Slc22a25 solute carrier family 22, member 25 affects localization
decreases activity
multiple interactions 		ISO Phorbol 12,13-Dibutyrate affects the localization of SLC22A9 protein
Phorbol 12,13-Dibutyrate results in decreased activity of SLC22A9 protein
Staurosporine inhibits the reaction [Phorbol 12,13-Dibutyrate affects the localization of SLC22A9 protein]; Staurosporine inhibits the reaction [Phorbol 12,13-Dibutyrate results in decreased activity of SLC22A9 protein] 		CTD PMID:17341544 NCBI chr 1:214,767,837...214,956,535
Ensembl chr 1:214,767,837...214,862,340 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]; Pregabalin inhibits the reaction [Phorbol 12,13-Dibutyrate promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:14499429 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP [alpha-Linolenic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein; [Arachidonic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein; [Docosahexaenoic Acids co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form; [Eicosapentaenoic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form; capsazepine inhibits the reaction [[Docosahexaenoic Acids co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form]; capsazepine inhibits the reaction [[Eicosapentaenoic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form]; Linolenic Acids promotes the reaction [[Docosahexaenoic Acids co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein modified form] CTD PMID:17038422 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
phorbol 13-acetate 12-myristate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of A2M mRNA CTD PMID:2440878 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]; eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]] CTD PMID:20438634 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions
decreases expression 		ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] CTD PMID:11331069 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in decreased expression of ABCC1 protein
Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein] 		CTD PMID:15517594 PMID:18473823 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions EXP Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] CTD PMID:18473823 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of ABCC4 mRNA CTD PMID:19142964 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA CTD PMID:19840844 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ACACA mRNA CTD PMID:37055963 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Ace angiotensin I converting enzyme increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA
carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein] 		CTD PMID:11158990 PMID:15071347 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Aco1 aconitase 1 multiple interactions
increases activity 		ISO
EXP 		Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein]
Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein] 		CTD PMID:10889193 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600 		JBrowse link
G Actb actin, beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA CTD PMID:15477007 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Adam12 ADAM metallopeptidase domain 12 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM12 mRNA CTD PMID:16979875 NCBI chr 1:198,116,968...198,443,680
Ensembl chr 1:198,116,975...198,447,552 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases response to substance
multiple interactions
increases expression 		ISO ADAM17 results in increased susceptibility to Tetradecanoylphorbol Acetate
ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]
Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein
[Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein] 		CTD PMID:12147693 PMID:23774263 PMID:24632454 PMID:26298005 PMID:28703301 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 multiple interactions
increases expression 		ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM8 mRNA
Tetradecanoylphorbol Acetate results in increased expression of ADAM8 mRNA 		CTD PMID:16979875 PMID:19945525 NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485 		JBrowse link
G Adm adrenomedullin decreases expression EXP Tetradecanoylphorbol Acetate results in decreased expression of ADM mRNA CTD PMID:11470465 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA CTD PMID:23519560 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802 		JBrowse link
G Adora3 adenosine A3 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA CTD PMID:23519560 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686 		JBrowse link
G Adra1a adrenoceptor alpha 1A increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of ADRA1A mRNA CTD PMID:7900855 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1d adrenoceptor alpha 1D increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of ADRA1D mRNA CTD PMID:7900855 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA CTD PMID:23519560 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of ADRB2 protein CTD PMID:14722251 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP protein CTD PMID:16368122 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]] CTD PMID:23541064 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agt angiotensinogen multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA CTD PMID:19840844 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization
increases expression
decreases expression
affects response to substance 		ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of AHR mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and affects the localization of AHR protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SAA3 mRNA]]; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein]
Tetradecanoylphorbol Acetate affects the localization of AHR protein
Tetradecanoylphorbol Acetate results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate results in increased expression of AHR protein
[Tetradecanoylphorbol Acetate co-treated with Tetrachlorodibenzodioxin] results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein]
Tetradecanoylphorbol Acetate results in decreased expression of AHR protein
AHR protein affects the susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:1313028 PMID:8390902 PMID:8396892 PMID:9415701 PMID:9706865 More... NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA
Tetradecanoylphorbol Acetate results in increased expression of AHRR mRNA 		CTD PMID:11423533 NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
decreases expression 		ISO [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA]
Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 protein 		CTD PMID:25463304 PMID:26198647 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA 		CTD PMID:18353537 PMID:26198647 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation 		ISO [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of AKT1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]
Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein
cyclosporin H inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] 		CTD PMID:20172950 PMID:20438634 PMID:20660715 PMID:22465218 PMID:25590691 More... NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of ALAS mRNA CTD PMID:15797241 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642 		JBrowse link
G Alb albumin decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA] 		CTD PMID:24211529 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA CTD PMID:19840844 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of ALOX5 protein; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein CTD PMID:10779545 PMID:11698504 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126 		JBrowse link
G Anxa1 annexin A1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ANXA1 mRNA CTD PMID:19945525 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Anxa10 annexin A10 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA10 mRNA CTD PMID:16979875 NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961 		JBrowse link
G Anxa2 annexin A2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ANXA2 protein CTD PMID:20045496 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631 		JBrowse link
G Anxa3 annexin A3 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA3 mRNA CTD PMID:16979875 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 affects expression ISO Tetradecanoylphorbol Acetate affects the expression of APAF1 protein CTD PMID:11139146 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions ISO [ferric chloride co-treated with Tetradecanoylphorbol Acetate] affects the localization of APEX1 protein CTD PMID:12023366 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of APEX2 mRNA CTD PMID:19031421 NCBI chr  X:22,914,943...22,937,713
Ensembl chr  X:22,914,944...22,936,011 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 multiple interactions
increases secretion 		ISO N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of APLP2 protein] CTD PMID:16279945 NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA CTD PMID:19840844 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP [phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of AQP4 protein in cultured astrocytes RGD PMID:28341892 RGD:597978120 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098 		JBrowse link
G Areg amphiregulin multiple interactions ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA]
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] 		CTD PMID:20660715 PMID:22643241 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arf1 ARF GTPase 1 affects localization ISO Tetradecanoylphorbol Acetate affects the localization of ARF1 protein CTD PMID:10931844 NCBI chr10:44,497,543...44,513,994 JBrowse link
G Arf6 ARF GTPase 6 affects localization ISO Tetradecanoylphorbol Acetate affects the localization of ARF6 protein CTD PMID:10931844 PMID:16280360 NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:93,569,234...93,610,536 		JBrowse link
G Arhgap20 Rho GTPase activating protein 20 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ARHGAP20 mRNA CTD PMID:31904401 NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:60,970,475...61,055,198 		JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARHGEF9 mRNA CTD PMID:16979875 NCBI chr  X:63,929,168...64,087,267
Ensembl chr  X:63,929,176...64,087,104 		JBrowse link
G Arl4c ARF like GTPase 4C multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARL4C mRNA CTD PMID:16979875 NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772 		JBrowse link
G Arl6ip5 ARF like GTPase 6 interacting protein 5 multiple interactions
increases expression 		ISO Tetradecanoylphorbol Acetate inhibits the reaction [Tretinoin results in increased expression of ARL6IP5 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of ARL6IP5 protein 		CTD PMID:16430862 PMID:16468075 NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:131,367,289...131,400,130 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein] CTD PMID:24481452 NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 multiple interactions ISO
EXP 		[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA]
Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] 		CTD PMID:15477007 PMID:16027158 NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:83,269,932...83,305,409 		JBrowse link
G Art3 ADP-ribosyltransferase 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA CTD PMID:23519560 NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,921,395...15,949,806 		JBrowse link
G Asf1a anti-silencing function 1A histone chaperone decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of ASF1A mRNA CTD PMID:26198647 NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639 		JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ASS1 mRNA CTD PMID:16979875 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA CTD PMID:15477007 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ATF5 mRNA CTD PMID:16979875 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of ATP1B1 mRNA CTD PMID:11204457 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
increases activity
decreases expression 		EXP Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA]
Tetradecanoylphorbol Acetate results in increased activity of ATP2A2 protein
Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 protein 		CTD PMID:17003265 PMID:19244478 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA CTD PMID:23519560 NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:45,809,271...45,848,747 		JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of Copper; ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA] CTD PMID:19205902 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:75,159,782...75,267,093 		JBrowse link
G Atp7b ATPase copper transporting beta multiple interactions ISO [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein CTD PMID:21189263 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801 		JBrowse link
G Aurka aurora kinase A increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of AURKA mRNA CTD PMID:19031421 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] CTD PMID:23541064 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of BACH1 mRNA CTD PMID:33268675 NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein CTD PMID:25446327 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bag1 BAG cochaperone 1 multiple interactions ISO BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA]; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:20858459 NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:60,864,476...60,878,161 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of BAK1 protein CTD PMID:11139146 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression 		ISO
EXP 		[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAX protein; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein]
Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BAX protein]
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] 		CTD PMID:15748703 PMID:19161993 PMID:22760862 PMID:25446327 PMID:32662567 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression 		ISO
EXP 		[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2 mRNA; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in decreased expression of BCL2 protein]
Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BCL2 protein]
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in decreased expression of BCL2 protein]
Tetradecanoylphorbol Acetate results in decreased expression of BCL2 protein 		CTD PMID:9295281 PMID:11139146 PMID:15538571 PMID:15748703 PMID:16979875 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions
increases expression 		ISO 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2A1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA] CTD PMID:15477007 PMID:16979875 PMID:20438634 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of BCL2L1 protein
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2L1 mRNA 		CTD PMID:11139146 PMID:18958680 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BECN1 protein CTD PMID:25446327 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases expression 		ISO CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BGLAP protein] CTD PMID:37562720 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Bgn biglycan multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA CTD PMID:19840844 NCBI chr  X:156,348,633...156,360,797
Ensembl chr  X:156,348,615...156,360,799 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA CTD PMID:16368122 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715 		JBrowse link
G Bik BCL2-interacting killer increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of BIK mRNA CTD PMID:26198647 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects localization ISO Tetradecanoylphorbol Acetate affects the localization of BIRC2 protein CTD PMID:15187025 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression 		ISO [2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] CTD PMID:14527959 PMID:24849683 PMID:31068361 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of BIRC5 mRNA CTD PMID:19031421 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger decreases response to substance ISO BMI1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate CTD PMID:24571310 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of BMP2 mRNA
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA] 		CTD PMID:10910055 PMID:21331654 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA] CTD PMID:21331654 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like multiple interactions
increases expression 		EXP Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA] CTD PMID:16291751 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase increases phosphorylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of BRAF protein
ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of BRAF protein] 		CTD PMID:17114644 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA CTD PMID:16368122 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763 		JBrowse link
G Bsg basigin multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]
Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA; Tetradecanoylphorbol Acetate results in increased expression of BSG protein 		CTD PMID:16860414 PMID:17055343 PMID:18647594 NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA CTD PMID:23519560 NCBI chr14:71,466,179...71,482,671
Ensembl chr14:71,466,180...71,482,647 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression 		ISO
EXP 		[Tetradecanoylphorbol Acetate co-treated with Go 6976] results in increased expression of BTG2 mRNA
Tetradecanoylphorbol Acetate results in increased expression of BTG2 mRNA
Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of BTG2 mRNA] 		CTD PMID:2005087 PMID:15302583 NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of BUB1B mRNA CTD PMID:19031421 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 affects response to substance
affects expression 		ISO NMES1 affects the susceptibility to Tetradecanoylphorbol Acetate
Tetradecanoylphorbol Acetate affects the expression of NMES1 		CTD PMID:16044405 NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089 		JBrowse link
G C4a complement C4A (Rodgers blood group) multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA CTD PMID:23519560 NCBI chr20:4,010,306...4,024,707 JBrowse link
G C4b complement C4B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA CTD PMID:23519560 NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289 		JBrowse link
G C5ar1 complement C5a receptor 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of C5AR1 protein CTD PMID:18559098 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G Ca14 carbonic anhydrase 14 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CA14 mRNA CTD PMID:16979875 NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CAR3 protein CTD PMID:20045496 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA CTD PMID:23519560 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634 		JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA CTD PMID:19840844 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calr calreticulin decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of CALR mRNA CTD PMID:19031421 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236 		JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I multiple interactions
increases phosphorylation 		ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein] CTD PMID:20590612 NCBI chr 4:148,036,843...148,047,675
Ensembl chr 4:148,036,824...148,047,245 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA CTD PMID:23519560 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Capn11 calpain 11 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN11 mRNA CTD PMID:16979875 NCBI chr 9:22,841,500...22,863,042
Ensembl chr 9:22,841,522...22,863,032 		JBrowse link
G Capn6 calpain 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CAPN6 mRNA CTD PMID:31904401 NCBI chr  X:112,177,467...112,202,178
Ensembl chr  X:112,177,467...112,202,178 		JBrowse link
G Capn9 calpain 9 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN9 mRNA CTD PMID:16979875 NCBI chr19:69,446,847...69,483,810
Ensembl chr19:69,446,847...69,483,810 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased cleavage of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA] CTD PMID:21515303 PMID:22322153 PMID:23430110 PMID:23535185 PMID:24158569 More... NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] CTD PMID:19631781 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression 		ISO [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of CASP3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased activity of CASP3 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in increased activity of CASP3 protein]
Tetradecanoylphorbol Acetate results in decreased expression of CASP3 protein 		CTD PMID:11139146 PMID:12165276 PMID:14610070 PMID:15538571 PMID:17309078 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP8 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] CTD PMID:12165276 PMID:15477007 PMID:18958680 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
decreases expression 		ISO [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of and results in increased cleavage of CASP9 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein]
Tetradecanoylphorbol Acetate results in decreased expression of CASP9 protein 		CTD PMID:17309078 PMID:24073338 PMID:25446327 PMID:32662567 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity 		ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CAT mRNA; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased oxidation of 1,2-diaminobenzene]
Tetradecanoylphorbol Acetate results in decreased expression of CAT protein
Tetradecanoylphorbol Acetate results in decreased activity of CAT protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of CAT protein; [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAT protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; CAT inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]; Tetradecanoylphorbol Acetate inhibits the reaction [Patulin results in decreased activity of CAT protein] 		CTD PMID:2126186 PMID:3030588 PMID:11243714 PMID:12065085 PMID:12504893 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav3 caveolin 3 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of CAV3 mRNA CTD PMID:15725944 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:147,137,797...147,153,967 		JBrowse link
G Cblif cobalamin binding intrinsic factor multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CBLIF mRNA CTD PMID:16979875 NCBI chr 1:218,030,756...218,045,004
Ensembl chr 1:218,030,731...218,045,117 		JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions ISO CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein] CTD PMID:25818598 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCL1 mRNA CTD PMID:16979875 NCBI chr10:67,625,962...67,628,740
Ensembl chr10:67,625,962...67,628,790 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL11 protein; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein] CTD PMID:17572062 PMID:17685462 PMID:21331654 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
increases secretion 		ISO 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL2 protein; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CCL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein]
Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein] 		CTD PMID:16376386 PMID:17572062 PMID:17685462 PMID:19063610 PMID:19945525 More... NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CCL20 mRNA CTD PMID:19945525 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:15477007 PMID:17572062 PMID:17685462 PMID:36416909 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression 		ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL4 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL4 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein]
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL4 protein] 		CTD PMID:9122163 PMID:17572062 PMID:17685462 PMID:18958680 PMID:31351099 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein]
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL5 mRNA 		CTD PMID:17572062 PMID:17685462 PMID:31904401 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA] CTD PMID:15117851 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA CTD PMID:31904401 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
increases expression
decreases expression 		ISO 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]
Tetradecanoylphorbol Acetate results in increased expression of CCNA2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein
Tetradecanoylphorbol Acetate results in decreased expression of CCNA2 protein 		CTD PMID:12421932 PMID:15949478 PMID:19031421 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression 		ISO PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA] CTD PMID:10866668 PMID:19000923 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnb2 cyclin B2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CCNB2 mRNA
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCNB2 mRNA 		CTD PMID:16979875 PMID:19031421 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression
decreases expression 		ISO 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCND1 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of CCND1 protein]
Tetradecanoylphorbol Acetate results in decreased expression of CCND1 protein 		CTD PMID:15949478 PMID:16368122 PMID:18922899 PMID:20438634 PMID:21375462 More... NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd3 cyclin D3 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein] 		CTD PMID:12421932 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Ccne1 cyclin E1 multiple interactions
increases expression 		ISO 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein] CTD PMID:12421932 PMID:24073338 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] CTD PMID:15477007 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] CTD PMID:15477007 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cd14 CD14 molecule multiple interactions
increases expression 		ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein]
Tetradecanoylphorbol Acetate results in increased expression of CD14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD14 protein 		CTD PMID:16430862 PMID:19135038 PMID:20089671 PMID:26036281 PMID:30218697 More... NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd200 Cd200 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] CTD PMID:15477007 NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569 		JBrowse link
G Cd28 Cd28 molecule multiple interactions
increases expression 		ISO Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of CD28 protein CTD PMID:8662792 PMID:11465111 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Cd302 CD302 molecule multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CD302 mRNA CTD PMID:31904401 NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737 		JBrowse link
G Cd34 CD34 molecule multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 mRNA; [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 protein
Tetradecanoylphorbol Acetate results in increased expression of CD34 protein 		CTD PMID:18922899 NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315 		JBrowse link
G Cd36 CD36 molecule decreases expression
increases expression
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in decreased expression of CD36 mRNA
Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD36 protein
tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]
2-chloro-5-nitrobenzanilide inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; [15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 mRNA; [Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [titanium dioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CD36 protein; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; Dibutyl Phthalate inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [[15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]] 		CTD PMID:12664607 PMID:16407258 PMID:16484594 PMID:21315065 PMID:23386263 More... NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3E protein] CTD PMID:2824607 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876 		JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3G protein] CTD PMID:2824607 NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918 		JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD4 mRNA CTD PMID:16979875 NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461 		JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD40 mRNA; Apigenin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; fisetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD40 protein]; Quercetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein] CTD PMID:16601352 PMID:16979875 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd40lg CD40 ligand increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CD40LG protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG protein 		CTD PMID:11297035 PMID:22851303 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA
Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein; Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] 		CTD PMID:9929743 PMID:15477007 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd68 Cd68 molecule increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CD68 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD68 protein CTD PMID:25128825 PMID:28720485 PMID:31011801 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cd69 Cd69 molecule increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CD69 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD69 protein
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein] 		CTD PMID:12749906 PMID:17962511 PMID:23134680 PMID:23941771 PMID:26343699 More... NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cd80 Cd80 molecule increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CD80 protein CTD PMID:30218697 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CD83 mRNA CTD PMID:31068361 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Cd9 CD9 molecule increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CD9 protein
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD9 mRNA 		CTD PMID:10910098 PMID:16979875 PMID:19840844 NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444 		JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression 		ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDC20 mRNA
Tetradecanoylphorbol Acetate results in increased expression of CDC20 mRNA 		CTD PMID:16979875 PMID:19031421 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799 		JBrowse link
G Cdc25b cell division cycle 25B increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CDC25B mRNA CTD PMID:19031421 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492 		JBrowse link
G Cdc25c cell division cycle 25C increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of CDC25C protein CTD PMID:21375462 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein] CTD PMID:25656647 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh17 cadherin 17 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] CTD PMID:15477007 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Cdh2 cadherin 2 multiple interactions
increases expression 		ISO antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein]
morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] 		CTD PMID:25656647 PMID:28108223 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdh5 cadherin 5 multiple interactions
increases phosphorylation 		ISO HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] CTD PMID:24211779 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
increases expression 		ISO corosolic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA] CTD PMID:10866668 PMID:32135139 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity
increases expression
multiple interactions
decreases phosphorylation 		ISO Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein
Tetradecanoylphorbol Acetate results in increased expression of CDK2 protein
Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein]
Tetradecanoylphorbol Acetate results in decreased phosphorylation of CDK2 protein 		CTD PMID:12421932 PMID:15978937 PMID:24073338 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of CDK4 mRNA
Tetradecanoylphorbol Acetate results in increased expression of CDK4 protein
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA] 		CTD PMID:10866668 PMID:15978937 PMID:24073338 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CDK6 protein CTD PMID:24073338 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Atrazine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Tetradecanoylphorbol Acetate promotes the reaction [Atrazine results in increased expression of CDKN1A mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter]
Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein 		CTD PMID:9348195 PMID:10910055 PMID:15735102 PMID:15976015 PMID:15978937 More... NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein
Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in increased expression of CDKN1B protein]
Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein] 		CTD PMID:12421932 PMID:26537528 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN1C mRNA CTD PMID:16979875 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA
[arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA 		CTD PMID:16368122 PMID:18922899 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN2B protein] CTD PMID:12421932 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNA CTD PMID:16979875 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA CTD PMID:23519560 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
decreases expression 		ISO Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein]
Tetradecanoylphorbol Acetate results in decreased expression of CEBPB mRNA 		CTD PMID:19282384 PMID:33268675 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cfh complement factor H multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CFH mRNA CTD PMID:31904401 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of CGA mRNA CTD PMID:21467749 NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CHAT mRNA CTD PMID:31904401 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416 		JBrowse link
G Chek1 checkpoint kinase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CHEK1 mRNA CTD PMID:19000923 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA CTD PMID:23519560 NCBI chr10:54,999,943...55,015,137
Ensembl chr10:55,002,788...55,015,107 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases expression
increases phosphorylation
increases activity 		ISO 15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein]
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein; Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] 		CTD PMID:10820281 PMID:15498850 PMID:16474181 PMID:21035309 PMID:23899529 More... NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CKS2 mRNA CTD PMID:19031421 NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519 		JBrowse link
G Cldn4 claudin 4 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CLDN4 mRNA CTD PMID:19945525 NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] CTD PMID:15477007 NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:190,586,650...190,597,929 		JBrowse link
G Clta clathrin, light chain A multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA CTD PMID:19840844 NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:63,041,184...63,059,215 		JBrowse link
G Cmah cytidine monophospho-N-acetylneuraminic acid hydroxylase multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMAHP mRNA CTD PMID:16979875 NCBI chr17:40,985,129...41,070,317
Ensembl chr17:41,011,641...41,070,252 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA CTD PMID:16979875 NCBI chr12:48,634,929...48,687,833
Ensembl chr12:48,634,003...48,691,458 		JBrowse link
G Cnn1 calponin 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of CNN1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CNN1 protein CTD PMID:15380616 NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482 		JBrowse link
G Cntn6 contactin 6 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNA CTD PMID:16979875 NCBI chr 4:138,911,090...139,307,339
Ensembl chr 4:138,911,380...139,311,816 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL11A1 mRNA CTD PMID:31904401 NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of COL1A2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNA
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA 		CTD PMID:16979875 PMID:18922899 PMID:19840844 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL2A1 mRNA CTD PMID:31904401 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] 		CTD PMID:15477007 PMID:19840844 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107 		JBrowse link
G Col8a1 collagen type VIII alpha 1 chain multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA CTD PMID:19840844 NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA CTD PMID:15477007 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Coro1b coronin 1B multiple interactions
increases phosphorylation
affects response to substance 		EXP
ISO 		Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CORO1B protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]
CORO1B protein modified form affects the susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:16027158 NCBI chr 1:210,872,437...210,877,876
Ensembl chr 1:210,871,841...210,877,876 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA CTD PMID:19840844 NCBI chr12:46,922,709...46,925,762
Ensembl chr12:46,912,648...46,925,768 		JBrowse link
G Cox8a cytochrome c oxidase subunit 8A multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA CTD PMID:19840844 NCBI chr 1:213,831,302...213,833,623
Ensembl chr 1:213,831,298...213,833,623 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation
increases activity 		ISO GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of CREB1 protein modified form]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]
Tetradecanoylphorbol Acetate results in increased activity of CREB1 protein 		CTD PMID:10601319 PMID:18791200 PMID:19282384 PMID:20032081 PMID:21047949 More... NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crebbp CREB binding protein multiple interactions ISO [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter] CTD PMID:16474181 PMID:19282384 PMID:21047949 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] CTD PMID:15477007 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA
lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA] 		CTD PMID:29462589 NCBI chr14:118,932...123,632
Ensembl chr14:115,497...123,631 		JBrowse link
G Crp C-reactive protein multiple interactions EXP CRP protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] CTD PMID:9767445 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CRTAM mRNA CTD PMID:16979875 NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:50,237,210...50,274,472 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CRY1 mRNA CTD PMID:19031421 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions
increases expression 		ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CSF2 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF2 mRNA; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein]
Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] 		CTD PMID:1376361 PMID:11752025 PMID:16979875 PMID:17051331 PMID:17572062 More... NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA CTD PMID:9122163 PMID:16979875 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] CTD PMID:15477007 NCBI chr14:81,679,956...81,707,331
Ensembl chr14:81,679,765...81,707,554 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression 		ISO Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein]
Tetradecanoylphorbol Acetate results in increased expression of CTNNB1 protein 		CTD PMID:24211779 PMID:25124862 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsb cathepsin B multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA CTD PMID:19840844 NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478 		JBrowse link
G Ctsd cathepsin D decreases cleavage ISO Tetradecanoylphorbol Acetate results in decreased cleavage of CTSD protein CTD PMID:36070022 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ctsg cathepsin G increases secretion
affects localization 		ISO Tetradecanoylphorbol Acetate results in increased secretion of CTSG protein
Tetradecanoylphorbol Acetate affects the localization of CTSG protein 		CTD PMID:25980585 PMID:34144024 NCBI chr15:33,901,230...33,907,596
Ensembl chr15:33,901,754...33,907,596 		JBrowse link
G Ctsh cathepsin H multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CTSH mRNA CTD PMID:31904401 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181 		JBrowse link
G Ctsl cathepsin L multiple interactions
decreases cleavage 		ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA
Tetradecanoylphorbol Acetate results in decreased cleavage of CTSL protein 		CTD PMID:19840844 PMID:36070022 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Cul5 cullin 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] CTD PMID:15477007 NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of CX3CL1 mRNA CTD PMID:19850645 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA CTD PMID:9122163 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
decreases expression 		ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA] CTD PMID:22359662 PMID:23519560 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA 		CTD PMID:22643241 PMID:23519560 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 multiple interactions
decreases expression 		ISO IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA] CTD PMID:22359662 NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression 		ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein 		CTD PMID:20852150 PMID:26513295 PMID:31351099 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression 		ISO [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA
Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA] 		CTD PMID:9122163 PMID:20172950 PMID:22359662 PMID:26513295 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CXCL6 mRNA CTD PMID:16979875 NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions
decreases expression 		ISO IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA] CTD PMID:22359662 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions
increases expression 		ISO [Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR1 protein; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA] CTD PMID:15265017 PMID:21045076 NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 multiple interactions ISO [Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR2 protein CTD PMID:15265017 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA
Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA] 		CTD PMID:11172467 PMID:20523355 PMID:21705328 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
increases activity
increases expression 		ISO Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA]
diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein] 		CTD PMID:9794432 PMID:29183754 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein] CTD PMID:15748703 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of CYP11A1 protein CTD PMID:18755854 PMID:18787026 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of CYP11B2 mRNA CTD PMID:15666830 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases activity 		ISO [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]
Tetradecanoylphorbol Acetate results in decreased activity of CYP19A1 protein 		CTD PMID:10338361 PMID:16357189 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
decreases expression
affects response to substance 		ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 protein; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased abundance of 2-Methoxyestradiol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein
Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 protein; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [benzotriphenylene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]
CYP1A1 protein affects the susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:1313028 PMID:1497680 PMID:8242868 PMID:8396892 PMID:9415701 More... NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer]
Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] 		CTD PMID:1313028 PMID:10620351 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression 		ISO Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Tetradecanoylphorbol Acetate results in decreased expression of CYP1B1 mRNA
chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] 		CTD PMID:9706865 PMID:10037446 PMID:11728381 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO Tetradecanoylphorbol Acetate promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:20206692 NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA] 		CTD PMID:32135139 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression 		ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol]
Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein 		CTD PMID:8531136 PMID:8798623 PMID:9143349 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP2F2 mRNA CTD PMID:16368122 NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA CTD PMID:16979875 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions
decreases expression
decreases activity 		ISO
EXP 		[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP7B1 mRNA
Tetradecanoylphorbol Acetate results in decreased expression of CYP7B1 mRNA
Tetradecanoylphorbol Acetate results in decreased activity of CYP7B1 protein 		CTD PMID:12029625 PMID:16368122 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804 		JBrowse link
G Dapk1 death associated protein kinase 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of DAPK1 mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA 		CTD PMID:10910055 PMID:23519560 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581 		JBrowse link
G Dapk2 death-associated protein kinase 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA CTD PMID:23519560 NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617 		JBrowse link
G Dct dopachrome tautomerase decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA
trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA]; trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT protein] 		CTD PMID:15892717 NCBI chr15:101,469,159...101,508,029
Ensembl chr15:101,469,159...101,508,029 		JBrowse link
G Defb5 defensin beta 5 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein] CTD PMID:28720485 NCBI chr16:77,315,424...77,317,828
Ensembl chr16:77,315,424...77,317,828 		JBrowse link
G Dio3 iodothyronine deiodinase 3 increases activity
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein
Hydrogen Peroxide promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein] 		CTD PMID:16935842 PMID:18420745 NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985 		JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA] 		CTD PMID:32135139 NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA CTD PMID:19840844 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:82,416,853...82,607,797 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 affects response to substance ISO DLK1 protein affects the susceptibility to Tetradecanoylphorbol Acetate CTD PMID:18575777 NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr14:5,833,111...5,867,154
Ensembl chr14:5,833,111...5,843,993 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of DNAJB9 mRNA CTD PMID:31068361 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] CTD PMID:10652249 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643 		JBrowse link
G Dner delta/notch-like EGF repeat containing multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of DNER mRNA CTD PMID:31904401 NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:93,035,108...93,350,568 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] CTD PMID:23775084 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119 		JBrowse link
G Dock8 dedicator of cytokinesis 8 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA] 		CTD PMID:32135139 NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:232,075,588...232,268,833 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DPYD mRNA CTD PMID:15705907 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions
increases expression 		ISO [Fluticasone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DUSP1 mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA] CTD PMID:15860753 PMID:20858459 PMID:31068361 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp13b dual specificity phosphatase 13B increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of DUSP13B mRNA CTD PMID:19031421 NCBI chr15:2,616,761...2,624,434
Ensembl chr15:2,609,049...2,624,887 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of DUSP2 mRNA CTD PMID:31068361 NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809 		JBrowse link
G Dusp22 dual specificity phosphatase 22 decreases methylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene] 		CTD PMID:32135139 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] CTD PMID:15477007 NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700 		JBrowse link
G E2f4 E2F transcription factor 4 multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein] CTD PMID:20479004 NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834 		JBrowse link
G Eea1 early endosome antigen 1 multiple interactions ISO Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] CTD PMID:22683840 NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of EEF1A1 protein CTD PMID:20045496 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions ISO phorbol 13-acetate 12-myristate inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] and decreases phosphorylation of EEF2 protein in colon cancer cells RGD PMID:31227218 RGD:153298919 NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:9,183,961...9,189,544 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of EFEMP1 mRNA CTD PMID:31904401 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808 		JBrowse link
G Efna4 ephrin A4 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EFNA4 mRNA CTD PMID:16979875 NCBI chr 2:177,046,463...177,050,713
Ensembl chr 2:177,046,463...177,050,713 		JBrowse link
G Egf epidermal growth factor multiple interactions
increases expression 		ISO
EXP 		pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein]
Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; TAPI-2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein; Zinc inhibits the reaction [Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]] 		CTD PMID:6309801 PMID:12947092 PMID:19447859 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases expression
increases phosphorylation 		ISO
EXP 		[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]
Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA
Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein
Tetradecanoylphorbol Acetate results in increased expression of EGFR protein
naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] 		CTD PMID:6309801 PMID:10516208 PMID:19447859 PMID:20660715 PMID:25866363 More... NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression 		ISO
EXP 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]
Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA
Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of EGR1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter]
Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein 		CTD PMID:2005087 PMID:10693946 PMID:10739673 PMID:10779383 PMID:10910055 More... NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Egr2 early growth response 2 multiple interactions
increases expression 		ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of EGR2 mRNA 		CTD PMID:15477007 PMID:31068361 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748 		JBrowse link
G Egr3 early growth response 3 multiple interactions EXP Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] CTD PMID:16091474 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712 		JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EGR4 mRNA CTD PMID:16979875 NCBI chr 4:119,605,358...119,607,817
Ensembl chr 4:119,605,357...119,608,368 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA CTD PMID:19840844 NCBI chr10:85,747,064...85,749,447
Ensembl chr 5:25,895,968...25,896,654
Ensembl chr10:25,895,968...25,896,654 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF2AK2 protein CTD PMID:30218697 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of EIF4A1 mRNA CTD PMID:31068361 NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions
increases phosphorylation 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; CGP 57380 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein] CTD PMID:9545260 PMID:12781867 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105 		JBrowse link
G Eif4e1b eukaryotic translation initiation factor 4E family member 1B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA CTD PMID:23519560 NCBI chr17:9,835,883...9,868,781
Ensembl chr17:9,836,362...9,860,681 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases phosphorylation 		ISO Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]
Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4EBP1 protein 		CTD PMID:12781867 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein] CTD PMID:12781867 NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of EIF4G2 protein CTD PMID:18491231 NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EIF5 mRNA CTD PMID:16979875 NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases activity
increases phosphorylation 		ISO Tetradecanoylphorbol Acetate results in increased activity of ELK1 protein
Tetradecanoylphorbol Acetate results in increased phosphorylation of ELK1 protein 		CTD PMID:18791200 PMID:21375462 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA CTD PMID:23519560 NCBI chr17:48,982,188...49,518,525
Ensembl chr17:48,982,188...49,518,159 		JBrowse link
G Eln elastin multiple interactions
decreases expression 		EXP [Okadaic Acid co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ELN mRNA
Tetradecanoylphorbol Acetate results in decreased expression of ELN mRNA 		CTD PMID:8997264 NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413 		JBrowse link
G Endog endonuclease G multiple interactions ISO [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein CTD PMID:17309078 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein] CTD PMID:24632381 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729 		JBrowse link
G Ephb6 Eph receptor B6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA CTD PMID:23519560 NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein CTD PMID:24704207 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
increases expression 		ISO PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein] CTD PMID:20479004 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases cleavage
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein] 		CTD PMID:9685416 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772 		JBrowse link
G Ereg epiregulin multiple interactions ISO Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EREG protein CTD PMID:15066986 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression 		ISO Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 protein; Tetradecanoylphorbol Acetate promotes the reaction [Estradiol results in increased expression of ESR1 protein]
Tetradecanoylphorbol Acetate results in decreased expression of ESR1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ESR1 protein 		CTD PMID:9706865 PMID:10633228 PMID:16368122 PMID:19340542 PMID:20559769 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
decreases expression 		ISO Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA] CTD PMID:10633228 PMID:20559769 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of EZH2 protein CTD PMID:35364107 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183 		JBrowse link
G F11r F11 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA CTD PMID:23519560 NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [F2 protein results in increased uptake of Manganese] CTD PMID:2125206 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
increases expression 		ISO ochratoxin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein
Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of F3 protein 		CTD PMID:9974427 PMID:18289624 PMID:25569083 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 mRNA; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 protein CTD PMID:30218697 PMID:37055963 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA] 		CTD PMID:21331654 PMID:23519560 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein; Tamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA] CTD PMID:20529085 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fau FAU ubiquitin like and ribosomal protein S30 fusion multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA CTD PMID:19840844 NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:212,779,473...212,781,026
Ensembl chr 1:212,779,473...212,781,026 		JBrowse link
G Fbln7 fibulin 7 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FBLN7 mRNA CTD PMID:31904401 NCBI chr 3:136,564,825...136,601,205
Ensembl chr 3:136,564,917...136,601,198 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of FEN1 mRNA CTD PMID:19031421 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016 		JBrowse link
G Fga fibrinogen alpha chain increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of FGA mRNA CTD PMID:2440878 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of FGB mRNA CTD PMID:2440878 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA CTD PMID:23519560 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA CTD PMID:23519560 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980 		JBrowse link
G Fgf16 fibroblast growth factor 16 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FGF16 mRNA CTD PMID:16979875 NCBI chr  X:74,882,863...74,893,598
Ensembl chr  X:74,882,995...74,944,246 		JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA CTD PMID:23519560 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
increases secretion 		EXP
ISO 		Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter]
Tetradecanoylphorbol Acetate results in increased secretion of FGF2 protein 		CTD PMID:10779383 PMID:11874475 PMID:15654655 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA CTD PMID:23519560 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions EXP
ISO 		Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA 		CTD PMID:15654655 PMID:23519560 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP
ISO 		Tetradecanoylphorbol Acetate results in increased expression of FGG mRNA CTD PMID:2440878 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
increases expression 		ISO BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA] CTD PMID:20858459 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression
increases secretion 		ISO ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FLT1 protein] CTD PMID:19205902 PMID:22197494 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA] CTD PMID:21331654 NCBI chr12:12,660,035...12,735,584
Ensembl chr12:12,659,946...12,735,581 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FMO5 mRNA CTD PMID:16979875 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression
increases secretion 		ISO 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FN1 mRNA; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FN1 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein] CTD PMID:15086456 PMID:16979875 PMID:24211529 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases activity
affects localization 		ISO
EXP 		1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOS mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]
Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOS protein
Tetradecanoylphorbol Acetate results in increased activity of FOS protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of FOS mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOS mRNA; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] 		CTD PMID:1932749 PMID:7564102 PMID:7963561 PMID:8386370 PMID:8631129 More... NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased expression of FOSB mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSB protein
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOSB mRNA 		CTD PMID:11113530 PMID:17148446 PMID:31068361 PMID:31904401 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO
EXP 		[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOSL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]
Tetradecanoylphorbol Acetate results in increased expression of FOSL1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein 		CTD PMID:9122163 PMID:11113530 PMID:17148446 PMID:18755854 PMID:19000923 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FOSL2 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] 		CTD PMID:15477007 PMID:16979875 PMID:17148446 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions
increases activity
decreases phosphorylation 		ISO FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2]
Tetradecanoylphorbol Acetate results in increased activity of FOXO3 protein
Tetradecanoylphorbol Acetate results in decreased phosphorylation of FOXO3 protein 		CTD PMID:21705328 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of FOXP3 protein CTD PMID:27865421 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Frmd3 FERM domain containing 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FRMD3 mRNA CTD PMID:31904401 NCBI chr 5:92,810,989...93,077,326
Ensembl chr 5:92,810,736...93,077,325 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions
increases expression 		ISO FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]
Tetradecanoylphorbol Acetate results in increased expression of FSCN1 mRNA 		CTD PMID:22102721 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:16,710,601...16,723,734 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of FSHB mRNA CTD PMID:21467749 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA CTD PMID:19840844 NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126 		JBrowse link
G Fstl4 follistatin-like 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FSTL4 mRNA CTD PMID:31904401 NCBI chr10:37,412,288...37,845,405
Ensembl chr10:37,412,288...37,845,393 		JBrowse link
G Fut4 fucosyltransferase 4 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of FUT4 protein CTD PMID:26036281 NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:19,868,079...19,872,436 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FXYD6 mRNA CTD PMID:31904401 NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715 		JBrowse link
G Fyb1 FYN binding protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] CTD PMID:15477007 NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:57,360,096...57,508,608 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA CTD PMID:23519560 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases expression 		ISO geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein] CTD PMID:23399806 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA CTD PMID:23519560 NCBI chr  X:155,301,979...155,543,870
Ensembl chr  X:155,303,928...155,543,863 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased expression of GABRA4 mRNA
Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] 		CTD PMID:16091474 NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,944,388...37,021,648 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GADD45A mRNA CTD PMID:10910055 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GAS6 mRNA CTD PMID:31904401 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088 		JBrowse link
G Gast gastrin increases secretion EXP Tetradecanoylphorbol Acetate results in increased secretion of GAST protein CTD PMID:19208342 NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880 		JBrowse link
G Gata1 GATA binding protein 1 multiple interactions
increases activity 		ISO Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter]
Tetradecanoylphorbol Acetate results in increased activity of GATA1 protein 		CTD PMID:14623254 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:17,201,633...17,209,459 		JBrowse link
G Gata2 GATA binding protein 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA
tellimagrandin I promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA] 		CTD PMID:14757314 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA CTD PMID:22398747 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Gata4 GATA binding protein 4 increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of GATA4 protein CTD PMID:11583584 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gatd1 glutamine amidotransferase class 1 domain containing 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GATD1 mRNA CTD PMID:31904401 NCBI chr 1:205,936,189...205,942,121
Ensembl chr 1:205,936,687...205,942,779 		JBrowse link
G Gba1 glucosylceramidase beta 1 multiple interactions ISO GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] CTD PMID:24951586 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:176,907,154...176,916,985 		JBrowse link
G Gbp3 guanylate binding protein 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA] CTD PMID:21331654 NCBI chr 2:234,144,042...234,173,527
Ensembl chr 2:234,146,519...234,180,055 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA
Tetradecanoylphorbol Acetate results in increased expression of GCLC mRNA 		CTD PMID:17200146 PMID:18154958 PMID:26198647 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression 		ISO 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] CTD PMID:24632381 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GCNT3 mRNA CTD PMID:26198647 NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595 		JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GDF10 mRNA CTD PMID:16979875 NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,243,317...9,256,794 		JBrowse link
G Gdf11 growth differentiation factor 11 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA] 		CTD PMID:32135139 NCBI chr 7:1,896,229...1,909,147
Ensembl chr 7:1,896,229...1,905,222 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression 		ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] CTD PMID:23996089 PMID:30218697 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of GFI1 mRNA CTD PMID:16888099 NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,187,286...2,196,730 		JBrowse link
G Gfra2 GDNF family receptor alpha 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] CTD PMID:15477007 NCBI chr15:52,351,499...52,443,369
Ensembl chr15:52,351,514...52,477,782 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases expression
decreases localization
increases phosphorylation
affects localization
increases expression 		ISO
EXP 		Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein]
Tetradecanoylphorbol Acetate results in decreased expression of GJA1 protein
Tetradecanoylphorbol Acetate results in decreased localization of GJA1 protein
Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein
Tetradecanoylphorbol Acetate results in decreased expression of GJA1 mRNA
Tetradecanoylphorbol Acetate affects the localization of GJA1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in decreased activity of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein
Tetradecanoylphorbol Acetate results in increased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein modified form
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] 		CTD PMID:7586169 PMID:7586191 PMID:8020150 PMID:8068183 PMID:8285856 More... NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gjb2 gap junction protein, beta 2 multiple interactions
decreases expression
increases expression 		ISO
EXP 		[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJB2 mRNA
Tetradecanoylphorbol Acetate results in decreased expression of GJB2 protein
Tetradecanoylphorbol Acetate results in increased expression of GJB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJB2 protein 		CTD PMID:7586191 PMID:8068183 PMID:8597533 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877 		JBrowse link
G Gjb5 gap junction protein, beta 5 multiple interactions
decreases expression 		ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJB5 mRNA
Tetradecanoylphorbol Acetate results in decreased expression of GJB5 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GJB5 protein 		CTD PMID:7586191 PMID:8597533 NCBI chr 5:144,965,133...144,968,051
Ensembl chr 5:144,964,751...144,984,021 		JBrowse link
G Glra1 glycine receptor, alpha 1 decreases activity EXP Tetradecanoylphorbol Acetate results in decreased activity of GLRA1 protein CTD PMID:7752562 NCBI chr10:40,128,284...40,228,612
Ensembl chr10:40,130,121...40,227,815 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GNRHR mRNA CTD PMID:16979875 NCBI chr14:22,211,666...22,229,654 JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha multiple interactions
increases expression 		ISO 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein] CTD PMID:20523355 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,829,832...55,854,560 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:9,018,762...9,072,552 JBrowse link
G Gpc4 glypican 4 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA CTD PMID:19840844 NCBI chr  X:136,565,536...136,676,142
Ensembl chr  X:136,565,591...136,676,057 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] CTD PMID:2523799 NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368 		JBrowse link
G Gpr3 G protein-coupled receptor 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GPR3 mRNA CTD PMID:31068361 NCBI chr 5:150,695,406...150,698,526
Ensembl chr 5:150,695,251...150,706,529 		JBrowse link
G Gpr84 G protein-coupled receptor 84 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GPR84 mRNA CTD PMID:31068361 NCBI chr 7:136,322,374...136,324,648
Ensembl chr 7:136,322,191...136,324,703 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GPX1 protein CTD PMID:10432307 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of GPX4 protein
Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of GPX4 protein] 		CTD PMID:10432307 PMID:35608139 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA CTD PMID:23519560 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:125,103,782...125,369,679 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA CTD PMID:23519560 NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962 		JBrowse link
G Grn granulin precursor increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GRN mRNA CTD PMID:16873554 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936 		JBrowse link
G Grp gastrin releasing peptide multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] CTD PMID:18313772 NCBI chr18:61,658,655...61,672,037
Ensembl chr18:61,658,250...61,672,037 		JBrowse link
G Grpr gastrin releasing peptide receptor increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of GRPR protein CTD PMID:29669290 NCBI chr  X:34,630,238...34,670,245
Ensembl chr  X:34,630,229...34,670,245 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases phosphorylation
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein
U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein] 		CTD PMID:17993264 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:89,943,669...89,953,593 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein
U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein] 		CTD PMID:17993264 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases activity
decreases activity
decreases expression 		ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of GSR protein; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP] CTD PMID:11243714 PMID:12504893 PMID:14997284 PMID:19161993 PMID:20691676 More... NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions ISO Tetradecanoylphorbol Acetate promotes the reaction [1,2-dithiol-3-thione results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benzylideneacetone results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Dimercaprol results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mercuric Chloride results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [sulforaphane results in increased expression of GSTA1 mRNA] CTD PMID:7568053 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
affects expression
affects response to substance
affects localization 		ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTA4 mRNA
Tetradecanoylphorbol Acetate affects the expression of GSTA4
GSTA4 affects the susceptibility to Tetradecanoylphorbol Acetate
Tetradecanoylphorbol Acetate affects the localization of GSTA4 protein 		CTD PMID:12646569 PMID:16044405 PMID:16368122 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA CTD PMID:19840844 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA CTD PMID:19840844 NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression 		ISO beta-lapachone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Emodin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; sanguinarine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter]
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA
Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 protein 		CTD PMID:14623254 PMID:15313406 PMID:15533597 PMID:19840844 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNA CTD PMID:16368122 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019 		JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of GTF2H4 mRNA CTD PMID:19031421 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760 		JBrowse link
G Gypa glycophorin A multiple interactions
decreases expression
increases expression 		ISO 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; chebulinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] CTD PMID:14769215 PMID:20523355 NCBI chr19:44,354,669...44,370,304
Ensembl chr19:44,354,706...44,370,291 		JBrowse link
G Gzmb granzyme B multiple interactions
increases expression 		ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein
Tetradecanoylphorbol Acetate results in increased expression of GZMB mRNA 		CTD PMID:20883105 PMID:30171972 NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA CTD PMID:15477007 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hal histidine ammonia lyase multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of HAL protein CTD PMID:20691676 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] CTD PMID:15477007 NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
increases secretion
increases expression 		ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of HBEGF mRNA
Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein
Tetradecanoylphorbol Acetate results in increased expression of HBEGF mRNA
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] 		CTD PMID:10910055 PMID:16979875 PMID:20660715 PMID:28703301 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA 		CTD PMID:15477007 PMID:23519560 NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein]
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased expression of HDAC5 protein]] 		CTD PMID:19124542 PMID:36075570 NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244 		JBrowse link
G Hdac9 histone deacetylase 9 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HDAC9 mRNA CTD PMID:31904401 NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:56,490,988...57,351,835 		JBrowse link
G Hdc histidine decarboxylase increases activity
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased activity of HDC protein
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein; atractylon inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; pyeongwee-san extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] 		CTD PMID:10428506 PMID:27553716 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711 		JBrowse link
G Hebp2 heme binding protein 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HEBP2 mRNA CTD PMID:31904401 NCBI chr 1:15,014,729...15,021,523
Ensembl chr 1:15,014,729...15,021,523 		JBrowse link
G Hells helicase, lymphoid specific increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of HELLS mRNA CTD PMID:19000923 NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:246,114,096...246,159,228 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions
increases expression 		ISO Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA
Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA; Tetradecanoylphorbol Acetate results in increased expression of HGF protein 		CTD PMID:15802798 PMID:23519560 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hhip Hedgehog-interacting protein multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA CTD PMID:23519560 NCBI chr19:44,768,038...44,856,878
Ensembl chr19:44,767,536...44,862,795 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Dithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]
Tetradecanoylphorbol Acetate results in increased expression of HIF1A mRNA alternative form; Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form 		CTD PMID:11424089 PMID:12479793 PMID:14695184 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] CTD PMID:15477007 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of HMGCR mRNA CTD PMID:12044893 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of HMGCS1 mRNA CTD PMID:12044893 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HMOX1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]]
HMOX1 enhancer affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA] 		CTD PMID:7538129 PMID:18078826 PMID:18958680 PMID:23288142 PMID:24632381 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions
increases expression 		ISO Indomethacin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HPGD mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein] CTD PMID:11237475 PMID:15680906 NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA CTD PMID:19840844 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of HRAS mRNA; HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein]
Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate co-treated with mezerein] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; [Benzo(a)pyrene co-treated with Tetradecanoylphorbol Acetate] affects the mutagenesis of HRAS gene; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of HRAS protein; [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA] 		CTD PMID:3115617 PMID:9766437 PMID:11241758 PMID:11765016 PMID:17106253 More... NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions
increases expression 		ISO Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRH1 mRNA] CTD PMID:23333628 NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions ISO HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] CTD PMID:19277450 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HS6ST2 mRNA CTD PMID:31904401 NCBI chr  X:135,887,224...136,182,388
Ensembl chr  X:135,888,472...136,182,353 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases activity
increases expression 		EXP Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein
Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA 		CTD PMID:16533503 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA CTD PMID:23519560 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of HSPA2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA2 mRNA CTD PMID:18958680 NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein] CTD PMID:10652249 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 multiple interactions ISO [2-butenal co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HSPA6 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA6 mRNA CTD PMID:18958680 PMID:24849683 NCBI chr13:85,805,911...85,807,052 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] CTD PMID:15477007 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA9 mRNA CTD PMID:18958680 NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases phosphorylation
increases expression 		EXP
ISO 		Pentobarbital inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HSPB1 protein]
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HSPB1 mRNA
Tetradecanoylphorbol Acetate results in increased phosphorylation of HSPB1 protein 		CTD PMID:7541446 PMID:10839933 PMID:31904401 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hyi hydroxypyruvate isomerase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HYI mRNA CTD PMID:31904401 NCBI chr 5:137,179,975...137,182,654
Ensembl chr 5:137,179,976...137,182,654 		JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IBSP mRNA CTD PMID:16979875 NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ICAM1 protein; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]
Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein 		CTD PMID:10484327 PMID:11164475 PMID:20920494 PMID:30218697 PMID:31351099 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ier2 immediate early response 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of IER2 mRNA CTD PMID:31068361 NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708 		JBrowse link
G Ier3 immediate early response 3 multiple interactions
increases expression 		ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA
Tetradecanoylphorbol Acetate results in increased expression of IER3 mRNA 		CTD PMID:19840844 PMID:19945525 PMID:31068361 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI27L2A mRNA CTD PMID:31904401 NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:128,363,658...128,365,146 		JBrowse link
G Ifi44 interferon-induced protein 44 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI44 mRNA CTD PMID:31904401 NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877 		JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
increases secretion 		ISO
EXP 		2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [Decitabine results in increased expression of PLA2G2A protein]]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]
Tetradecanoylphorbol Acetate results in increased expression of IFNG protein
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] 		CTD PMID:1371491 PMID:12411406 PMID:12755381 PMID:12812920 PMID:14623498 More... NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] CTD PMID:15477007 NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IGF1 mRNA; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:10365914 PMID:16368122 PMID:31904401 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions
increases phosphorylation 		ISO corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] CTD PMID:26513295 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] promotes the reaction [Arsenic results in increased expression of IGF2R mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IGF2R mRNA CTD PMID:38299738 NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP1 mRNA CTD PMID:16368122 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
increases expression 		ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP3 mRNA
Tetradecanoylphorbol Acetate results in increased expression of IGFBP3 mRNA 		CTD PMID:16368122 PMID:19945525 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP5 mRNA CTD PMID:16979875 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA CTD PMID:16979875 NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
increases phosphorylation
increases activity 		ISO 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]
Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein 		CTD PMID:16474181 PMID:20584749 PMID:23899529 PMID:26220752 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein]
Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein] 		CTD PMID:12115659 PMID:31351099 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
increases secretion
decreases expression 		ISO
EXP 		4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL10 protein]; quinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA
Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA
6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [Silicon Dioxide co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased secretion of IL10 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; Genistein affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]
Tetradecanoylphorbol Acetate results in decreased expression of IL10 mRNA 		CTD PMID:12884291 PMID:15502056 PMID:15588918 PMID:15614042 PMID:16374615 More... NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il11 interleukin 11 multiple interactions
increases expression 		ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA] CTD PMID:22138297 NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO IL12A results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:22359662 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of IL12B mRNA
Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] 		CTD PMID:15614042 PMID:36416909 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of IL12RB1 protein
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA] 		CTD PMID:11441113 PMID:21331654 NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,654,207...18,666,824 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of IL12RB2 protein
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL12RB2 mRNA 		CTD PMID:11441113 PMID:16979875 NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:97,756,089...97,844,937 		JBrowse link
G Il13 interleukin 13 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of IL13 mRNA
[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]
6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA] 		CTD PMID:10428506 PMID:21331654 PMID:22398747 PMID:25114106 PMID:26091108 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA] CTD PMID:21331654 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression 		ISO 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL17A protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein; biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein]; enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Genistein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; hexaconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; T0901317 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; triflumizol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; yakuchinone-A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL17A protein]
[Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein 		CTD PMID:22289359 PMID:22292739 PMID:25583575 PMID:26513295 PMID:27783946 More... NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions
decreases response to substance 		ISO [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; IL17RA results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] CTD PMID:22359662 NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:155,339,400...155,362,382 		JBrowse link
G Il18r1 interleukin 18 receptor 1 multiple interactions ISO [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL18R1 protein CTD PMID:14994387 NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression 		ISO 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; [sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]; diacerein inhibits the reaction [[sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]
Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1A protein
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA] 		CTD PMID:7665919 PMID:8435107 PMID:8702551 PMID:9122163 PMID:11851881 More... NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion 		ISO
EXP 		[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1B mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; [Soot co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Poly dA-dT] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL1B protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein]
Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]
Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1B protein
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] 		CTD PMID:9122163 PMID:9584910 PMID:10072544 PMID:12812920 PMID:14623498 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions
increases expression 		ISO SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA] CTD PMID:21045076 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 multiple interactions
increases expression 		ISO SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA] CTD PMID:21045076 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAP mRNA CTD PMID:16979875 NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342 		JBrowse link
G Il1rapl2 interleukin 1 receptor accessory protein-like 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAPL2 mRNA CTD PMID:16979875 NCBI chr  X:105,547,403...107,080,369
Ensembl chr  X:105,754,490...107,065,223 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of IL1RL1 mRNA CTD PMID:19000923 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions
increases expression 		ISO NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein] CTD PMID:10072544 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il2 interleukin 2 increases secretion
multiple interactions
increases expression 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dexamethasone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Formaldehyde co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Isoniazid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [isophorone diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mitomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pyrimethamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Warfarin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Alitretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Lenalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter]; norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; SB 203580 inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL2 protein
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [bis(tri-n-butyltin)oxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Dronabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; KN 93 inhibits the reaction [Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein] 		CTD PMID:1371491 PMID:7815356 PMID:8658534 PMID:8662742 PMID:9439728 More... NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il21 interleukin 21 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] CTD PMID:22077062 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il23r interleukin 23 receptor multiple interactions ISO 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA] CTD PMID:22292739 NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:97,909,972...98,004,110 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha multiple interactions
increases expression
increases secretion 		ISO
EXP 		[Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2RA mRNA; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein]; Sirolimus inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2RA protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein]
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; tetrathiomolybdate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2RA protein 		CTD PMID:7815356 PMID:8586487 PMID:9766631 PMID:12421932 PMID:12749906 More... NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] CTD PMID:15477007 NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537 		JBrowse link
G Il3 interleukin 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL3 mRNA 		CTD PMID:1376361 PMID:16979875 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il33 interleukin 33 multiple interactions
increases expression 		ISO FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL33 mRNA] CTD PMID:35717073 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Il4 interleukin 4 multiple interactions
increases secretion
increases expression 		ISO
EXP 		4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL4 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein]; hispidulin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; Leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]
6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Toluene 2,4-Diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of IL4 mRNA 		CTD PMID:1371491 PMID:8658534 PMID:9766631 PMID:10428506 PMID:12709020 More... NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 multiple interactions
increases expression
increases secretion 		ISO
EXP 		2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]
deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein]
Tetradecanoylphorbol Acetate results in increased expression of IL5 mRNA 		CTD PMID:1371491 PMID:8658534 PMID:12884291 PMID:16116958 PMID:16374615 More... NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il5ra interleukin 5 receptor subunit alpha decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of IL5RA mRNA CTD PMID:8049355 NCBI chr 4:141,186,749...141,221,348
Ensembl chr 4:141,171,158...141,220,943 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion 		ISO
EXP 		[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL6 protein
3'(R)-O-beta-D-glucopyranosyl-3',4'-dihydroxanthyletin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of IL6 protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with 2-Propanol] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Sodium Dodecyl Sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL6 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; levistolide A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; tepoxalin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased secretion of IL6 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] 		CTD PMID:7759567 PMID:9122163 PMID:10072544 PMID:10428506 PMID:12884291 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL6R mRNA CTD PMID:16979875 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Il9r interleukin 9 receptor multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL9R mRNA CTD PMID:16979875 NCBI chr10:15,936,156...15,947,613
Ensembl chr10:15,936,156...15,947,613 		JBrowse link
G Inhbc inhibin subunit beta C multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA] CTD PMID:21331654 NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO
EXP 		[Tetradecanoylphorbol Acetate co-treated with Glucose] results in increased secretion of INS1 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein]
Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Glucose results in increased secretion of INS1 protein] 		CTD PMID:2523799 PMID:10221768 PMID:17069794 PMID:30761839 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA
IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] 		CTD PMID:19840844 PMID:23680697 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IRAK3 mRNA
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IRAK3 mRNA 		CTD PMID:16979875 PMID:31904401 NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706 		JBrowse link
G Ireb2 iron responsive element binding protein 2 increases activity
multiple interactions 		EXP
ISO 		Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] 		CTD PMID:10889193 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520 		JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions
decreases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA]
Tetradecanoylphorbol Acetate results in decreased expression of IRF4 mRNA 		CTD PMID:15477007 PMID:33268675 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730 		JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] CTD PMID:21331654 NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ISG15 mRNA CTD PMID:31904401 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Itga2 integrin subunit alpha 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of ITGA2 mRNA
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA] 		CTD PMID:17669516 PMID:21331654 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itga2b integrin subunit alpha 2b multiple interactions
increases expression 		ISO 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] CTD PMID:10428506 PMID:20523355 NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833 		JBrowse link
G Itga5 integrin subunit alpha 5 multiple interactions
increases expression 		ISO Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] CTD PMID:24211529 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305 		JBrowse link
G Itga7 integrin subunit alpha 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA CTD PMID:23519560 NCBI chr 7:1,944,447...1,973,347
Ensembl chr 7:1,944,460...1,973,339 		JBrowse link
G Itgal integrin subunit alpha L multiple interactions
affects localization 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGAL protein] CTD PMID:20883105 NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
increases localization 		ISO
EXP 		2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; [salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA; dimemorfan inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]
PMA increases expression of Itgam protein on neutrophils
PMA increases expression of ITGAM protein on monocytes
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]
Tetradecanoylphorbol Acetate results in increased expression of ITGAM mRNA; Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein 		CTD
RGD		 PMID:10739673 PMID:11504768 PMID:16430862 PMID:16617325 PMID:18500357 More... RGD:329901912, RGD:329901662 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itgax integrin subunit alpha X multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGAX mRNA CTD PMID:16979875 NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression
affects localization
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein
Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; crenatoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] 		CTD PMID:16393473 PMID:20883105 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions
increases expression 		ISO 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; tellimagrandin I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] CTD PMID:10910098 PMID:14757314 PMID:14769215 PMID:20523355 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Itgb6 integrin subunit beta 6 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGB6 mRNA CTD PMID:16979875 NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333 		JBrowse link
G Itgb8 integrin subunit beta 8 multiple interactions ISO [2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ITGB8 mRNA CTD PMID:24849683 NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:146,165,484...146,351,245 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of ITPR1 protein alternative form CTD PMID:24073338 NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:142,743,334...143,066,504 		JBrowse link
G Ivl involucrin multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] CTD PMID:10866668 PMID:17148446 NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578 		JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] CTD PMID:26091108 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases phosphorylation
multiple interactions
increases expression
increases localization
affects localization 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased activity of JUN protein
Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein; [JUN gene mutant form results in increased activity of JUN protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein; [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of JUN protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]
Tetradecanoylphorbol Acetate results in increased expression of JUN; Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]
[Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]]
Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein; Tetradecanoylphorbol Acetate results in increased expression of JUN protein modified form 		CTD PMID:1730747 PMID:1932749 PMID:8219202 PMID:8386370 PMID:9067545 More... NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO
EXP 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]
Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA]
Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA
Tetradecanoylphorbol Acetate results in increased expression of JUNB; Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUNB protein 		CTD PMID:1932749 PMID:8631129 PMID:11113530 PMID:15666830 PMID:15920718 More... NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer]
Tetradecanoylphorbol Acetate results in increased expression of JUND mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUND protein 		CTD PMID:1932749 PMID:10620351 PMID:11507057 PMID:17148446 PMID:18755854 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 decreases activity ISO Tetradecanoylphorbol Acetate results in decreased activity of KCND3 protein alternative form CTD PMID:11709419 NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:195,626,316...195,843,690 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 decreases activity ISO Tetradecanoylphorbol Acetate results in decreased activity of KCNE1 protein CTD PMID:1655403 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:45,064,162...45,081,247 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 decreases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA] 		CTD PMID:16385079 NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:254,590,175...254,613,898 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions EXP Tetradecanoylphorbol Acetate inhibits the reaction [KCNJ4 protein results in decreased susceptibility to Rotenone] CTD PMID:18619942 NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:112,922,532...112,954,826 		JBrowse link
G Kif20a kinesin family member 20A multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KIF20A mRNA CTD PMID:16979875 NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909 		JBrowse link
G Kif20b kinesin family member 20B increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of KIF20B mRNA CTD PMID:19031421 NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451 		JBrowse link
G Kif23 kinesin family member 23 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of KIF23 mRNA CTD PMID:19031421 NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856 		JBrowse link
G Kif2c kinesin family member 2C increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of KIF2C mRNA CTD PMID:19031421 NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212 		JBrowse link
G Klf12 KLF transcription factor 12 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KLF12 mRNA CTD PMID:16979875 NCBI chr15:83,037,548...83,469,998
Ensembl chr15:83,045,463...83,670,640 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] CTD PMID:15477007 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] CTD PMID:15477007 NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 increases expression
multiple interactions 		EXP
ISO 		Tetradecanoylphorbol Acetate results in increased expression of KPNB1 protein
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] 		CTD PMID:16365892 PMID:17615583 NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,642,082...82,670,856 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS protein 		CTD PMID:15263067 PMID:16368122 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Krt18 keratin 18 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNA CTD PMID:16368122 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848 		JBrowse link
G Krt8 keratin 8 multiple interactions ISO [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein CTD PMID:16368122 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA CTD PMID:23519560 NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173 		JBrowse link
G Lamb1 laminin subunit beta 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LAMB1 mRNA CTD PMID:16979875 NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:53,563,073...53,630,760 		JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA CTD PMID:23519560 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions
increases phosphorylation 		ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA; KT 5926 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of LCP1 protein] CTD PMID:14769871 PMID:15477007 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA; Tetradecanoylphorbol Acetate results in increased expression of LDLR protein
Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] 		CTD PMID:29499335 PMID:31068361 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA CTD PMID:23519560 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Lgals3 galectin 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA CTD PMID:19840844 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:23,086,841...23,111,737 		JBrowse link
G Lgals8 galectin 8 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of LGALS8 mRNA; [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Vehicle Emissions] results in increased expression of LGALS8 mRNA CTD PMID:18353537 NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetrachlorodibenzodioxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP] 		CTD PMID:2153673 PMID:21467749 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions
increases expression 		ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LIF mRNA
Tetradecanoylphorbol Acetate results in increased expression of LIF mRNA 		CTD PMID:16979875 PMID:26198647 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Lmo2 LIM domain only 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of LMO2 mRNA CTD PMID:7544155 NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:110,809,912...110,833,075 		JBrowse link
G Lmo7 LIM domain 7 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LMO7 mRNA CTD PMID:16979875 NCBI chr15:84,981,689...85,184,554
Ensembl chr15:84,981,735...85,184,551 		JBrowse link
G Lox lysyl oxidase multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA CTD PMID:19840844 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lpl lipoprotein lipase increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of LPL protein
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LPL protein
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA 		CTD PMID:18435438 PMID:19840844 PMID:30218697 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of LRP1 protein
very low density lipoprotein triglyceride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA] 		CTD PMID:15910848 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] CTD PMID:15477007 NCBI chr 1:91,727,769...91,759,822
Ensembl chr 1:91,727,769...91,760,006 		JBrowse link
G Lum lumican multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of LUM mRNA CTD PMID:31904401 NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MAD1L1 mRNA CTD PMID:19031421 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MAD2L1 mRNA CTD PMID:19031421 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222 		JBrowse link
G Madd MAP-kinase activating death domain decreases methylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene] 		CTD PMID:32135139 NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:97,570,787...97,613,509 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA CTD PMID:23519560 NCBI chr 4:127,762,590...128,368,228
Ensembl chr 4:127,762,590...128,367,833 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein] CTD PMID:20479004 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
increases activity
increases phosphorylation 		ISO [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]
Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein
3,5,3',4',5'-pentahydroxy-stilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] 		CTD PMID:8816498 PMID:11861786 PMID:16945329 PMID:17693661 PMID:18767048 More... NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
increases phosphorylation 		ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:11861786 PMID:15477007 PMID:20479004 PMID:30218697 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein] CTD PMID:15944151 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] CTD PMID:27278863 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions ISO [MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] CTD PMID:27278863 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA CTD PMID:19840844 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MAP3K14 mRNA CTD PMID:10910055 NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
increases expression 		ISO
EXP 		1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK1 protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Colforsin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK1 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
Tetradecanoylphorbol Acetate results in increased expression of MAPK1; Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein 		CTD PMID:8616849 PMID:8816498 PMID:9545260 PMID:9728050 PMID:10037446 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases activity
increases phosphorylation 		ISO SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]
Tetradecanoylphorbol Acetate results in increased activity of MAPK14 protein
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein] 		CTD PMID:12781867 PMID:14610070 PMID:15944151 PMID:15949478 PMID:16838270 More... NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity
increases expression 		ISO
EXP 		1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Resveratrol results in decreased activity of MAPK3 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK3 protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK3 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein
1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK3 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
Tetradecanoylphorbol Acetate results in increased expression of MAPK3; Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein 		CTD PMID:8616849 PMID:8816498 PMID:9545260 PMID:10037446 PMID:10660688 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation 		ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]
Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] 		CTD PMID:14610070 PMID:16838270 PMID:17114644 PMID:19447859 PMID:20172950 More... NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 multiple interactions EXP MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] CTD PMID:11513749 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation 		ISO Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]
CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] 		CTD PMID:16838270 PMID:17693661 PMID:19447859 PMID:20599481 PMID:21354279 More... NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases activity ISO Tetradecanoylphorbol Acetate results in increased activity of MAPKAPK2 protein CTD PMID:9545260 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA CTD PMID:19840844 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882 		JBrowse link
G Marcksl1 MARCKS-like 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MARCKSL1 mRNA CTD PMID:31904401 NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417 		JBrowse link
G Mark1 microtubule affinity regulating kinase 1 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK1 protein CTD PMID:30218697 NCBI chr13:98,981,727...99,086,998
Ensembl chr13:98,983,020...99,086,701 		JBrowse link
G Mark2 microtubule affinity regulating kinase 2 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK2 protein CTD PMID:30218697 NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:213,890,213...213,955,149 		JBrowse link
G Mark3 microtubule affinity regulating kinase 3 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK3 protein CTD PMID:30218697 NCBI chr 6:136,447,327...136,537,409
Ensembl chr 6:136,448,531...136,537,404 		JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MBL2 mRNA CTD PMID:16979875 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MCL1 mRNA CTD PMID:31068361 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MCM3 mRNA CTD PMID:19000923 NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746 		JBrowse link
G Meox2 mesenchyme homeobox 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MEOX2 mRNA CTD PMID:16979875 NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:59,583,785...59,644,700 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase increases cleavage ISO Tetradecanoylphorbol Acetate results in increased cleavage of MERTK protein CTD PMID:17047157 NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192 		JBrowse link
G Mest mesoderm specific transcript multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MEST mRNA CTD PMID:31904401 NCBI chr 4:60,321,814...60,332,288
Ensembl chr 4:60,316,102...60,333,509 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MGMT mRNA 		CTD PMID:12663516 PMID:31904401 NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482 		JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions ISO [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MIF mRNA; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans]]; Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans] CTD PMID:9122163 PMID:26852939 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mir125b1 microRNA 125b-1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MIR125B1 mRNA CTD PMID:33268675 NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:50,850,036...50,850,122 		JBrowse link
G Mir146a microRNA 146a multiple interactions
increases expression 		ISO hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein] CTD PMID:30090394 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mir155 microRNA 155 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MIR155 mRNA CTD PMID:33268675 NCBI chr11:37,261,114...37,261,178
Ensembl chr11:37,261,114...37,261,178 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MKI67 protein CTD PMID:22981962 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 multiple interactions
increases phosphorylation
increases activity 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein] CTD PMID:9545260 PMID:12781867 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:134,554,943...134,594,393 		JBrowse link
G Mme membrane metallo-endopeptidase decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of MME protein CTD PMID:16997790 NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression 		ISO BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]
Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein 		CTD PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
increases expression 		ISO Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]
Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein 		CTD PMID:19656660 PMID:20004183 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions
increases expression 		ISO 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein]
Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein 		CTD PMID:20152819 PMID:20599481 PMID:21354279 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
increases activity
multiple interactions
increases secretion 		ISO Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form
Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein
3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein] 		CTD PMID:10455257 PMID:10569804 PMID:15962302 PMID:17498959 PMID:18155510 More... NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp21 matrix metallopeptidase 21 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MMP21 mRNA CTD PMID:16984259 NCBI chr 1:197,910,178...197,915,847
Ensembl chr 1:197,910,178...197,915,847 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression 		ISO BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]
Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein 		CTD PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of MMP7 mRNA CTD PMID:8798622 NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755 		JBrowse link
G Mmp8 matrix metallopeptidase 8 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MMP8 mRNA CTD PMID:16979875 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases secretion
increases expression
increases activity 		ISO
EXP 		[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of MMP9 protein; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein
Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein]
Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein
Tetradecanoylphorbol Acetate results in increased secretion of MMP9 mRNA; Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein
Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine co-treated with kahweol acetate] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with pyrazolanthrone] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 mRNA]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Curcumin promotes the reaction [3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Hesperidin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; iron protoporphyrin IX inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; N-2-(4-bromophenyl) ethyl caffeamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Nitrites inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 promotes the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Sildenafil Citrate promotes the reaction [Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; solithromycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein; Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Y 27632 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein] 		CTD PMID:9848099 PMID:10455257 PMID:10569804 PMID:12745093 PMID:14515793 More... NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity
increases secretion 		ISO [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; [Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein; Carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; CMI 392 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; GSK484 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Irinotecan promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; phenethyl isothiocyanate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [Dimethyl Sulfoxide results in increased expression of MPO mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased oxidation of 1,2-diaminobenzene]
12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2-(4-hydroxy-3,5-dimethylphenyl)-5-methoxy-3-methylindole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; E 6080 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Mangifera indica extract inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO]; SC 41930 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]; zileuton inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] 		CTD PMID:3030588 PMID:7812673 PMID:8113982 PMID:8273558 PMID:10381133 More... NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA CTD PMID:19840844
G Mrc1 mannose receptor, C type 1 multiple interactions
increases expression 		ISO corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein]
Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein 		CTD PMID:26497364 PMID:32135139 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Ms4a2 membrane spanning 4-domains A2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA] CTD PMID:21331654 NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:217,865,159...217,873,108 		JBrowse link
G Msln mesothelin multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MSLN mRNA CTD PMID:16979875 NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153 		JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions
increases expression 		ISO 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MSR1 protein; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]]
Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form 		CTD PMID:9614211 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070 		JBrowse link
G Mt1a metallothionein 1A multiple interactions
increases response to substance 		ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA
MT1 results in increased susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:9506445 PMID:19840844 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mt2 metallothionein 2 multiple interactions
increases response to substance
increases expression 		ISO [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MT2A mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA]
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MT2 mRNA
MT2 results in increased susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:9506445 PMID:18958680 PMID:20858459 PMID:31904401 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of MTOR protein CTD PMID:31068361 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MUC1 mRNA CTD PMID:16979875 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions
increases secretion
increases expression 		EXP
ISO 		resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein]
Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein
Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein
2''-O-acetyl-polygalacin D2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; deapi-platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein]; deapi-platycodin D promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platycodin D3 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA] 		CTD PMID:22213337 PMID:24290472 PMID:25590691 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006 		JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MX1 mRNA CTD PMID:31904401 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
increases expression 		ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA; catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; Glucose affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in decreased expression of MYC mRNA]
Tetradecanoylphorbol Acetate results in decreased expression of MYC mRNA
Tetradecanoylphorbol Acetate results in increased expression of MYC; Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC protein; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA]
Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MYC protein 		CTD PMID:2558650 PMID:8219202 PMID:10381133 PMID:10739673 PMID:12749906 More... NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] CTD PMID:23680697 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA CTD PMID:23519560 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Mzf1 myeloid zinc finger 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MZF1 mRNA CTD PMID:16979875 NCBI chr 1:82,742,709...82,755,069
Ensembl chr 1:82,742,726...82,753,820 		JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA CTD PMID:15477007 NCBI chr 8:117,132,957...117,136,207
Ensembl chr 8:117,133,494...117,136,207 		JBrowse link
G Nap1l3 nucleosome assembly protein 1-like 3 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NAP1L3 mRNA CTD PMID:16979875 NCBI chr  X:92,607,628...92,610,426
Ensembl chr  X:92,604,626...92,610,687 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 multiple interactions
affects localization 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCAM1 protein] CTD PMID:20883105 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NCAPG mRNA CTD PMID:19031421 NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases phosphorylation
increases expression
affects localization 		ISO Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NCF1 protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein]
Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein 		CTD PMID:7575484 PMID:9794432 PMID:11172467 PMID:11246141 PMID:25980585 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions
affects localization 		ISO Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] CTD PMID:11246141 PMID:21705328 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149 		JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NEK2 mRNA CTD PMID:19031421 NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056 		JBrowse link
G Nell1 neural EGFL like 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA CTD PMID:15477007 NCBI chr 1:108,845,462...109,709,858
Ensembl chr 1:108,845,462...109,709,858 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of NFATC1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in decreased expression of NFATC1 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of NFATC1 protein; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] CTD PMID:21603612 PMID:24244623 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein; Acetic Acid inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]
6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the localization of NFATC2 protein]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of and results in decreased phosphorylation of NFATC2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased phosphorylation of and affects the localization of NFATC2 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased phosphorylation of and affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein] 		CTD PMID:17615583 PMID:21603612 PMID:23941771 PMID:25114106 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions ISO [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]
NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] 		CTD PMID:12709020 PMID:21603612 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions ISO NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] CTD PMID:21603612 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases activity
increases expression 		ISO [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFE2L2 protein; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFE2L2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein
Tetradecanoylphorbol Acetate results in increased activity of NFE2L2 protein 		CTD PMID:20438634 PMID:24632381 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfib nuclear factor I/B multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFIB mRNA CTD PMID:16979875 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases activity
increases expression
affects localization 		ISO
EXP 		1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFKB1 mRNA; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]
Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein; Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein modified form
[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein 		CTD PMID:8573121 PMID:9122163 PMID:9973483 PMID:10692565 PMID:14527959 More... NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
increases expression
decreases expression
increases phosphorylation
affects localization
increases degradation 		ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased degradation of NFKBIA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of NFKBIA mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]
Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein
Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein 		CTD PMID:9434740 PMID:10072544 PMID:12115659 PMID:15330761 PMID:15477007 More... NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein CTD PMID:20026373 NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366 		JBrowse link
G Nfkbil1 NFKB inhibitor like 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFKBIL1 mRNA CTD PMID:16979875 NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,595,284...3,610,294 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NFKBIZ mRNA CTD PMID:31068361 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Ngf nerve growth factor multiple interactions ISO
EXP 		[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased expression of NGF protein
Tetradecanoylphorbol Acetate inhibits the reaction [NGF protein results in increased expression of NR4A1 mRNA]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA 		CTD PMID:2005087 PMID:23519560 PMID:24244623 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NKD2 mRNA CTD PMID:23519560 NCBI chr 1:31,268,856...31,299,390
Ensembl chr 1:31,272,519...31,299,387 		JBrowse link
G Nkg7 natural killer cell granule protein 7 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] CTD PMID:15477007 NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:102,981,450...102,982,562 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NLRP3 mRNA CTD PMID:23937860 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nmi N-myc (and STAT) interactor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA CTD PMID:15477007 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NOLC1 mRNA CTD PMID:19031421 NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions
increases expression 		ISO decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS1 protein] CTD PMID:31351099 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases activity
increases expression 		ISO
EXP 		[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]
Tetradecanoylphorbol Acetate results in increased activity of NOS2A protein
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [ginsenoside Rg3 results in increased expression of NOS2 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]
Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein
Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Hydrolyzable Tannins inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; protocatechuic acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]
Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein; Tetradecanoylphorbol Acetate results in increased expression of NOS2A protein 		CTD PMID:12086399 PMID:14534150 PMID:14700523 PMID:15016631 PMID:16647178 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein] 		CTD PMID:31351099 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Notch3 notch receptor 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] CTD PMID:15477007 NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,784,272...11,834,778 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions ISO NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] CTD PMID:21705328 NCBI chr10:14,226,473...14,230,541
Ensembl chr10:14,228,205...14,230,541 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of NPHS1 mRNA CTD PMID:16820792 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NPLOC4 protein CTD PMID:30218697 NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264 		JBrowse link
G Nppa natriuretic peptide A increases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA; Tetradecanoylphorbol Acetate results in increased expression of NPPA protein
(+)-JQ1 compound inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA protein]; MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]; Mifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] 		CTD PMID:11470465 PMID:11513749 PMID:16533503 PMID:19244478 PMID:23939492 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Npy neuropeptide Y multiple interactions
decreases expression 		ISO
EXP 		Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]
Tetradecanoylphorbol Acetate results in decreased expression of NPY protein 		CTD PMID:10660688 PMID:19912776 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NPY1R mRNA CTD PMID:31904401 NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression 		ISO 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein
Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein
ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 protein] 		CTD PMID:16979875 PMID:18752316 PMID:24481452 PMID:24632381 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO2 mRNA CTD PMID:16979875 NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions
decreases expression 		ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter]
Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein 		CTD PMID:18787026 PMID:19282384 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NR1H2 mRNA CTD PMID:31011801 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NR1H3 mRNA CTD PMID:31011801 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of NR1I2 protein] CTD PMID:18473823 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression
multiple interactions
increases expression 		ISO
EXP 		Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 protein
[Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein; Salmeterol Xinafoate promotes the reaction [[Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein]
Tetradecanoylphorbol Acetate results in increased expression of NR3C1 mRNA 		CTD PMID:15860753 PMID:16533503 PMID:21533367 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of NR3C2 mRNA CTD PMID:16533503 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects localization
multiple interactions
increases expression 		ISO
EXP 		Tetradecanoylphorbol Acetate affects the localization of NR4A1 protein
Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of NR4A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [NGF protein results in increased expression of NR4A1 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of NR4A1 mRNA
Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein]
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A1 mRNA 		CTD PMID:2005087 PMID:12376465 PMID:16979875 PMID:18787026 PMID:19282384 More... NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A2 mRNA CTD PMID:16979875 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A3 mRNA CTD PMID:15477007 PMID:16979875 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions ISO NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA] CTD PMID:18787026 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions ISO alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] CTD PMID:16357189 NCBI chr13:50,865,253...50,985,107
Ensembl chr13:50,867,920...50,984,938 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA; U 0126 inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA] CTD PMID:21047912 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Nrxn2 neurexin 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NRXN2 mRNA CTD PMID:23519560 NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:213,155,673...213,271,526 		JBrowse link
G Nsg2 neuronal vesicle trafficking associated 2 increases methylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene] 		CTD PMID:32135139 NCBI chr10:16,106,073...16,165,915
Ensembl chr10:16,147,325...16,165,915 		JBrowse link
G Ntf3 neurotrophin 3 multiple interactions
increases expression 		EXP Tetradecanoylphorbol Acetate inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [imetit results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein]
Tetradecanoylphorbol Acetate results in increased expression of NTF3 protein 		CTD PMID:19854260 PMID:21276809 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NTRK2 mRNA CTD PMID:31904401 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628 		JBrowse link
G Nts neurotensin multiple interactions
decreases activity 		ISO 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Sucrose promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Go 6976 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NTS protein results in increased chemical synthesis of Inositol Phosphates]; Tetradecanoylphorbol Acetate inhibits the reaction [Ro 31-8220 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Staurosporine results in increased activity of NTS protein] CTD PMID:18313772 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961 		JBrowse link
G Nup54 nucleoporin 54 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NUP54 mRNA CTD PMID:19000923 NCBI chr14:15,901,936...15,920,335
Ensembl chr14:15,901,991...15,920,334 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of NUSAP1 mRNA CTD PMID:19031421 NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OAS2 mRNA CTD PMID:31904401 NCBI chr12:41,464,568...41,492,036
Ensembl chr12:41,467,315...41,495,881 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
increases expression 		ISO pyridaben inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]
bullatacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Colchicine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Glutathione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; phenethyl isothiocyanate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Podophyllotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Sodium Selenite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vitamin E inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein 		CTD PMID:1923905 PMID:2591024 PMID:3098411 PMID:7653998 PMID:9270009 More... NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Olfml2a olfactomedin-like 2A multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OLFML2A mRNA CTD PMID:31904401 NCBI chr 3:43,098,299...43,127,621
Ensembl chr 3:43,098,299...43,127,621 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA] CTD PMID:23386263 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Olr1523 olfactory receptor 1523 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OR4D1 mRNA CTD PMID:31904401 NCBI chr10:73,205,498...73,206,439 JBrowse link
G Oprm1 opioid receptor, mu 1 increases expression
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA
[phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of Oprm1 protein in cultured astrocytes
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]
Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA] 		CTD
RGD		 PMID:11901219 PMID:18652891 PMID:28341892 RGD:597978120 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Otc ornithine transcarbamylase multiple interactions
increases activity 		EXP [Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Gossypol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] CTD PMID:3097147 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:15,126,358...15,239,555 		JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA CTD PMID:23519560 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of P2RY1 mRNA CTD PMID:23519560 NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027 		JBrowse link
G P2ry2 purinergic receptor P2Y2 multiple interactions EXP Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium] CTD PMID:17003265 NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions EXP PAFAH1B1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Phosphatidylcholines] CTD PMID:12013527 NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196 		JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PAK3 mRNA CTD PMID:19031421 NCBI chr  X:111,912,967...112,171,037
Ensembl chr  X:111,913,059...112,165,035 		JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA CTD PMID:23519560 NCBI chr 3:126,092,576...126,128,320
Ensembl chr 3:126,093,013...126,128,318 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PAPSS2 mRNA CTD PMID:31904401 NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616 		JBrowse link
G Pard6b par-6 family cell polarity regulator beta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNA CTD PMID:23519560 NCBI chr 3:177,209,429...177,230,509
Ensembl chr 3:177,209,258...177,230,510 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
affects response to substance
increases activity 		ISO 3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of PARP1 protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [cholix toxin, Vibrio cholerae results in increased cleavage of PARP1 protein]
PARP1 protein affects the susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:2120135 PMID:2126186 PMID:16323285 PMID:17309078 PMID:28087840 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PARP2 mRNA CTD PMID:19031421 NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891 		JBrowse link
G Pbk PDZ binding kinase increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PBK mRNA CTD PMID:19031421 NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA CTD PMID:19840844 NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412 		JBrowse link
G Pcdha2 protocadherin alpha 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCDHA2 mRNA CTD PMID:16979875
G Pcna proliferating cell nuclear antigen multiple interactions
increases expression 		ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of PCNA protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]; Masoprocol affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]] CTD PMID:10866668 PMID:19840844 PMID:20043298 PMID:25770929 PMID:32662567 More... NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCOLCE mRNA CTD PMID:16979875 NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287 		JBrowse link
G Pcp4 Purkinje cell protein 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PCP4 mRNA CTD PMID:31904401 NCBI chr11:49,229,185...49,331,186
Ensembl chr11:49,270,186...49,331,186 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 mRNA
Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein] 		CTD PMID:21873647 PMID:26513295 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pde1b phosphodiesterase 1B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDE1B mRNA CTD PMID:23519560 NCBI chr 7:136,505,834...136,533,034
Ensembl chr 7:136,505,689...136,533,033 		JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA
Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA] 		CTD PMID:10352363 PMID:10428506 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions
increases expression 		ISO
EXP 		Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFB mRNA]
Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA] 		CTD PMID:9650640 PMID:10352363 PMID:10428506 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA CTD PMID:19840844 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA CTD PMID:19840844 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein] 		CTD PMID:29458014 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Penk proenkephalin increases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased expression of PENK mRNA
Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PENK mRNA] 		CTD PMID:11113530 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions ISO [Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA] CTD PMID:23291558 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA] CTD PMID:22643241 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PHEX mRNA CTD PMID:19000923 NCBI chr  X:41,422,561...41,671,226
Ensembl chr  X:41,426,101...41,671,226 		JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PHKA2 mRNA
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PYK protein 		CTD PMID:23519560 PMID:30218697 NCBI chr  X:37,979,629...38,102,656
Ensembl chr  X:37,979,629...38,102,144 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CB mRNA CTD PMID:23519560 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CD mRNA CTD PMID:23519560 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PIK3R5 mRNA CTD PMID:19000923 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions ISO E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:20479004 NCBI chr 8:27,465,538...27,477,016 JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] CTD PMID:18953428 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases phosphorylation ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of PLA2G4A protein CTD PMID:10874129 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Plat plasminogen activator, tissue type increases secretion
increases expression 		ISO Tetradecanoylphorbol Acetate results in increased secretion of PLAT protein
Tetradecanoylphorbol Acetate results in increased expression of PLAT protein 		CTD PMID:3119194 PMID:8018658 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
increases expression
increases secretion 		ISO arsenic trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of PLAU protein]
Tetradecanoylphorbol Acetate results in increased expression of PLAU protein
TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PLAU protein] 		CTD PMID:9848099 PMID:15962302 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plcb2 phospholipase C, beta 2 affects localization
multiple interactions 		ISO Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein
edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein] 		CTD PMID:9295281 NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221 		JBrowse link
G Plcg2 phospholipase C, gamma 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLCG2 mRNA CTD PMID:23519560 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684 		JBrowse link
G Pld1 phospholipase D1 increases activity
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased activity of PLD1 protein
toxB protein, Clostridium difficile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLD1 protein] 		CTD PMID:14769825 PMID:15067002 NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245 		JBrowse link
G Pld2 phospholipase D2 multiple interactions
increases activity 		ISO
EXP 		PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Tetradecanoylphorbol Acetate results in increased activity of PLD2 protein 		CTD PMID:15067002 PMID:18423386 NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,754,988...55,771,435 		JBrowse link
G Plek pleckstrin increases phosphorylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein
Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein] 		CTD PMID:8928743 NCBI chr14:95,598,650...95,631,326
Ensembl chr14:95,598,654...95,655,721 		JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLIN2 protein CTD PMID:30218697 NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878 		JBrowse link
G Plk1 polo-like kinase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PLK1 mRNA CTD PMID:19031421 NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637 		JBrowse link
G Plxdc2 plexin domain containing 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PLXDC2 mRNA CTD PMID:31904401 NCBI chr17:84,077,793...84,502,831
Ensembl chr17:84,104,864...84,497,999 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] CTD PMID:15477007 NCBI chr  X:46,200,351...46,205,517
Ensembl chr  X:46,193,332...46,205,089 		JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of POLE2 mRNA CTD PMID:19031421 NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361 		JBrowse link
G Pot1 protection of telomeres 1 decreases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in increased expression of POT1 mRNA 		CTD PMID:26330309 NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of POU2F1 protein CTD PMID:16241859 NCBI chr13:80,653,602...80,796,279
Ensembl chr13:80,663,714...80,796,356 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] CTD PMID:15477007 NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564 		JBrowse link
G Pou4f3 POU class 4 homeobox 3 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of POU4F3 mRNA CTD PMID:16979875 NCBI chr18:34,641,191...34,643,783
Ensembl chr18:34,641,191...34,643,783 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
increases activity 		ISO
EXP 		PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSPO mRNA]
Tetradecanoylphorbol Acetate results in increased expression of PPARA mRNA
Tetradecanoylphorbol Acetate results in increased activity of PPARA protein 		CTD PMID:11701232 PMID:16042408 PMID:17360982 PMID:22205965 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions
increases expression 		ISO PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA]
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSPO mRNA]
Tetradecanoylphorbol Acetate results in increased expression of PPARD mRNA 		CTD PMID:10866668 PMID:22205965 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased activity of PPARG protein
Tetradecanoylphorbol Acetate results in increased expression of PPARG mRNA; Tetradecanoylphorbol Acetate results in increased expression of PPARG protein
[2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of troglitazone]; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] affects the expression of PPARG mRNA; [Tetradecanoylphorbol Acetate results in increased expression of PPARG] which affects the susceptibility to troglitazone; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein] 		CTD PMID:12044893 PMID:15707588 PMID:16945329 PMID:21511917 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppbp pro-platelet basic protein multiple interactions
increases expression 		ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PPBP mRNA
Tetradecanoylphorbol Acetate results in increased expression of PPBP protein 		CTD PMID:15316029 PMID:23519560 NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PPP1R15A mRNA CTD PMID:31068361 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PPP1R1B mRNA CTD PMID:31904401 NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,844,036...83,853,063 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha multiple interactions ISO PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] CTD PMID:23775084 NCBI chr10:36,856,534...36,878,789 JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] CTD PMID:23775084 NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634 		JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PRDX2 protein CTD PMID:20045496 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PREX1 mRNA CTD PMID:23519560 NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764 		JBrowse link
G Prf1 perforin 1 multiple interactions ISO 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein CTD PMID:30171972 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRICKLE1 mRNA CTD PMID:31904401 NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:126,518,587...126,614,581 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases expression
decreases expression
affects localization
increases phosphorylation
increases activity
increases localization
decreases phosphorylation 		ISO
EXP 		[Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein
Tetradecanoylphorbol Acetate results in increased expression of PRKCA protein modified form
Tetradecanoylphorbol Acetate results in decreased expression of PRKCA protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of PRKCA protein]
Tetradecanoylphorbol Acetate results in increased localization of PRKCA protein
Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Egtazic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate binds to and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCA protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]
Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCA protein 		CTD PMID:9852137 PMID:10651808 PMID:10656618 PMID:12590138 PMID:12720544 More... NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions
decreases expression
increases phosphorylation
affects localization
increases activity
decreases phosphorylation 		ISO [Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCB protein]; PRKCB protein affects the reaction [Tetradecanoylphorbol Acetate affects the localization of Zinc]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCB protein]
Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein modified form
Tetradecanoylphorbol Acetate affects the localization of PRKCB protein; Tetradecanoylphorbol Acetate affects the localization of PRKCB protein alternative form
Tetradecanoylphorbol Acetate results in increased activity of PRKCB protein
Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein 		CTD PMID:1724372 PMID:9852137 PMID:10651808 PMID:15330761 PMID:15380616 More... NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
decreases expression
affects localization
increases activity
increases phosphorylation
increases localization
affects phosphorylation 		ISO
EXP 		2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCD protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; PRKCD protein affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with benz(a)anthracene]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein
PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCD protein
Tetradecanoylphorbol Acetate results in decreased expression of PRKCD protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of and affects the localization of PRKCD protein
Tetradecanoylphorbol Acetate results in increased localization of PRKCD protein 		CTD PMID:9852137 PMID:10567579 PMID:10656618 PMID:11424089 PMID:12755590 More... NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
decreases expression
affects localization
increases activity 		ISO
EXP 		PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein
Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein
Tetradecanoylphorbol Acetate affects the localization of PRKCE protein
[Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein
PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCE protein
Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCE protein 		CTD PMID:11507057 PMID:12003851 PMID:12590138 PMID:14623285 PMID:14975926 More... NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkcg protein kinase C, gamma decreases expression
affects localization
multiple interactions
increases activity 		ISO
EXP 		Tetradecanoylphorbol Acetate results in decreased expression of PRKCG protein
Tetradecanoylphorbol Acetate affects the localization of PRKCG protein
naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCG protein]
[Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]
Tetradecanoylphorbol Acetate results in increased activity of PRKCG protein 		CTD PMID:14975926 PMID:15707588 PMID:15949478 PMID:18652891 PMID:19447859 More... NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Prkch protein kinase C, eta increases activity
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein
[Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein] 		CTD PMID:16832347 NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:98,027,646...98,226,477 		JBrowse link
G Prkci protein kinase C, iota increases localization
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein
wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein] 		CTD PMID:21295103 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784 		JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein] CTD PMID:16241859 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508 		JBrowse link
G Prkcz protein kinase C, zeta affects localization
increases expression
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate affects the localization of PRKCZ protein
Tetradecanoylphorbol Acetate results in increased expression of PRKCZ protein modified form
Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCZ protein 		CTD PMID:12590138 PMID:15976015 PMID:16532021 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Prkd1 protein kinase D1 multiple interactions
increases phosphorylation
affects localization
increases expression
affects phosphorylation 		ISO
EXP 		2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein]
TPA affects localization of Prkd1 protein in cardiomyocytes
PMA increases phosphorylation of Prkd1 protein in neonatal ventricular myocytes
Tetradecanoylphorbol Acetate results in increased expression of PRKD1 protein modified form
Tetradecanoylphorbol Acetate affects the localization of PRKD1 protein
[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKD1 protein 		CTD
RGD		 PMID:9852137 PMID:15380616 PMID:16532021 PMID:19124542 PMID:21047949 More... RGD:288084581, RGD:243065275 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509 		JBrowse link
G Prkd2 protein kinase D2 increases phosphorylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein]; kb-NB142-70 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein] 		CTD PMID:24634417 PMID:37562720 NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:86,642,629...86,670,675 		JBrowse link
G Prl prolactin increases expression
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased expression of PRL mRNA
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] 		CTD PMID:3097147 PMID:21467749 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Procr protein C receptor multiple interactions
increases expression
decreases cleavage
affects localization 		ISO [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PROCR protein modified form]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PROCR protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of PROCR protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]]
Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein] 		CTD PMID:23774263 PMID:24632454 PMID:26298005 NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989 		JBrowse link
G Prxl2b peroxiredoxin like 2B multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRXL2B mRNA CTD PMID:31904401 NCBI chr 5:170,744,953...170,747,556
Ensembl chr 5:170,744,953...170,747,556 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] CTD PMID:22398747 NCBI chr19:50,740,808...50,743,292
Ensembl chr19:50,740,811...50,743,210 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] CTD PMID:22398747 NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PSMC2 protein CTD PMID:16343552 NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of PSMC6 protein CTD PMID:16343552 NCBI chr15:21,022,314...21,043,785
Ensembl chr15:21,022,314...21,043,785 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
increases phosphorylation 		EXP RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] CTD PMID:11297424 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408 		JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions
increases phosphorylation 		EXP Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTGER3 protein alternative form] CTD PMID:15937517 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of PTGES mRNA CTD PMID:18922899 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptgfr prostaglandin F receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTGFR mRNA CTD PMID:23519560 NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:243,393,350...243,425,623 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of PTGS1; Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein] 		CTD PMID:10381133 PMID:12086399 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases activity 		ISO
EXP 		3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3-methylquercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
Tetradecanoylphorbol Acetate results in increased expression of PTGS2; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein
1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; 3,4-dihydroxyphenylethanol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of 8-epi-prostaglandin F2alpha; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Thromboxane B2; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTGS2 mRNA; Apigenin affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; beta-ionone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Gallic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein; tricin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
[Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; midostaurin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] 		CTD PMID:8621535 PMID:8989914 PMID:9013627 PMID:9576062 PMID:9705326 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pthlh parathyroid hormone-like hormone increases secretion EXP Tetradecanoylphorbol Acetate results in increased secretion of PTHLH protein CTD PMID:7946399 NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454 		JBrowse link
G Ptk2 protein tyrosine kinase 2 multiple interactions
increases expression
increases phosphorylation 		ISO [oxophenylarsine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with oxotremorine M] results in increased phosphorylation of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein; [Vanadates co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Wortmannin co-treated with Tetradecanoylphorbol Acetate] inhibits the reaction [oxotremorine M results in increased phosphorylation of PTK2 protein]; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTK2 protein]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein]]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTK2 protein]; oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein] CTD PMID:10537051 PMID:10569804 PMID:24211529 PMID:28527916 PMID:37562720 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of PTK2B protein CTD PMID:16877402 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Ptn pleiotrophin multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA CTD PMID:19840844 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482 		JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTPRN2 mRNA CTD PMID:16979875 NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of PTTG1 mRNA
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA 		CTD PMID:19031421 PMID:19840844 NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309 		JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTX3 mRNA CTD PMID:16979875 NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 protein; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]
Tetradecanoylphorbol Acetate results in increased expression of RAC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein modified form 		CTD PMID:18922899 PMID:21705328 PMID:28527916 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions ISO RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:11145705 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Rack1 receptor for activated C kinase 1 multiple interactions ISO 1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12782152 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948 		JBrowse link
G Rad21 RAD21 cohesin complex component increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RAD21 mRNA CTD PMID:19000923 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:85,177,716...85,204,657 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RAD51AP1 mRNA CTD PMID:19000923 PMID:19031421 NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680 		JBrowse link
G Rad51c RAD51 paralog C increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RAD51C mRNA CTD PMID:19031421 NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143 		JBrowse link
G Rad54l RAD54 like multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RAD54L mRNA CTD PMID:16979875 NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:134,811,532...134,841,425 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions
increases expression
increases activity 		ISO [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein]; Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] CTD PMID:14623285 PMID:19161993 PMID:22760862 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with salvin] results in increased expression of RARA protein CTD PMID:11504768 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RARRES1 mRNA CTD PMID:16979875 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024 		JBrowse link
G Rasal3 RAS protein activator like 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RASAL3 mRNA CTD PMID:31904401 NCBI chr 7:12,047,090...12,061,883
Ensembl chr 7:12,047,090...12,061,883 		JBrowse link
G Rassf2 Ras association domain family member 2 decreases methylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene] 		CTD PMID:32135139 NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:139,697,187...139,733,368 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases phosphorylation
increases expression
decreases phosphorylation 		ISO 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]
Tetradecanoylphorbol Acetate results in increased expression of RB1 protein modified form
Tetradecanoylphorbol Acetate results in decreased phosphorylation of RB1 protein 		CTD PMID:8927716 PMID:9348195 PMID:12421932 PMID:15978937 PMID:16979875 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RBBP8 mRNA CTD PMID:19031421 NCBI chr18:3,198,188...3,263,643
Ensembl chr18:3,197,310...3,263,985 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 increases expression ISO PMA increases expression of RBFOX2 mRNA in monocytes RGD PMID:29771377 RGD:329849002 NCBI chr 7:110,691,230...110,934,901
Ensembl chr 7:110,691,230...110,934,987 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of RBPJ protein CTD PMID:23134680 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:61,551,366...61,736,307 		JBrowse link
G Rbx1 ring-box 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RBX1 mRNA CTD PMID:19031421 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:114,870,972...114,881,191 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions
affects localization 		ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of REL mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of REL protein] CTD PMID:9122163 PMID:15477007 PMID:16376386 NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases phosphorylation
increases expression
increases localization
increases activity
affects localization 		ISO
EXP 		3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; Lipopolysaccharides analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein
1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of and results in increased localization of RELA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein; [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]
Tetradecanoylphorbol Acetate results in increased expression of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of RELA protein modified form
resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] 		CTD PMID:8573121 PMID:9973483 PMID:10692565 PMID:14527959 PMID:15090542 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Resp18 regulated endocrine-specific protein 18 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RESP18 mRNA CTD PMID:31904401 NCBI chr 9:84,213,844...84,220,186
Ensembl chr 9:84,213,467...84,221,299 		JBrowse link
G Rfc4 replication factor C subunit 4 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RFC4 mRNA CTD PMID:19031421 NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730 		JBrowse link
G Rfc5 replication factor C subunit 5 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RFC5 mRNA CTD PMID:19031421 NCBI chr12:44,868,322...44,877,879
Ensembl chr12:44,862,329...44,878,151 		JBrowse link
G Rgcc regulator of cell cycle multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGCC mRNA
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RGCC mRNA 		CTD PMID:16979875 PMID:31904401 NCBI chr15:61,071,574...61,084,408
Ensembl chr15:61,071,574...61,084,408 		JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS11 mRNA CTD PMID:16979875 NCBI chr10:15,727,279...15,735,536
Ensembl chr10:15,727,279...15,735,536 		JBrowse link
G Rgs13 regulator of G-protein signaling 13 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS13 mRNA CTD PMID:16979875 NCBI chr13:58,472,604...58,505,922
Ensembl chr13:58,472,604...58,505,922 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RGS16 mRNA CTD PMID:31068361 NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions EXP RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] CTD PMID:11297424 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884 		JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 multiple interactions ISO RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] CTD PMID:28703301 NCBI chr10:102,331,991...102,359,117
Ensembl chr10:102,331,991...102,359,117 		JBrowse link
G Rhog ras homolog family member G multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] CTD PMID:15477007 NCBI chr 1:166,030,685...166,046,254
Ensembl chr 1:166,017,427...166,044,787 		JBrowse link
G Rif1 replication timing regulatory factor 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of RIF1 mRNA CTD PMID:19000923 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Rnaset2 ribonuclease T2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] CTD PMID:15477007 NCBI chr 1:55,133,532...55,150,701
Ensembl chr 1:55,117,492...55,150,701 		JBrowse link
G Rnf187 ring finger protein 187 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein
TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] 		CTD PMID:25851810 NCBI chr10:44,209,080...44,214,979
Ensembl chr10:44,202,332...44,215,470 		JBrowse link
G Rnf4 ring finger protein 4 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Colforsin] results in increased expression of RNF4 mRNA CTD PMID:14749358 NCBI chr14:80,625,864...80,647,138
Ensembl chr14:80,625,866...80,647,148 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ROCK1 protein CTD PMID:24760326 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147 		JBrowse link
G Rpe65 retinoid isomerohydrolase RPE65 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RPE65 mRNA CTD PMID:31904401 NCBI chr 2:251,425,228...251,457,209
Ensembl chr 2:251,425,368...251,457,156 		JBrowse link
G Rpl7 ribosomal protein L7 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA CTD PMID:19840844 NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451 		JBrowse link
G Rps11 ribosomal protein S11 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA CTD PMID:19840844 NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:104,742,155...104,744,337 		JBrowse link
G Rps20 ribosomal protein S20 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA CTD PMID:19840844 NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621
Ensembl chr 9:42,839,965...43,095,621
Ensembl chr 5:42,839,965...43,095,621 		JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
increases phosphorylation 		ISO [Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein]
Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein
Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein] 		CTD PMID:16832347 PMID:18245498 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 increases phosphorylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] 		CTD PMID:17693661 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
increases phosphorylation 		ISO SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]]; Sodium Salicylate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein
Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] 		CTD PMID:10993886 PMID:30696844 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Rspo3 R-spondin 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RSPO3 mRNA CTD PMID:31904401 NCBI chr 1:30,112,529...30,197,267
Ensembl chr 1:30,112,114...30,197,938 		JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RT1-DA protein CTD PMID:9536116 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-DMb RT1 class II, locus DMb multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of H2-DMB1 mRNA CTD PMID:23519560 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246 		JBrowse link
G Rtp4 receptor (chemosensory) transporter protein 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RTP4 mRNA CTD PMID:31904401 NCBI chr11:90,741,992...90,840,061
Ensembl chr11:90,741,992...90,753,851 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
increases expression 		ISO CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RUNX2 protein] CTD PMID:37562720 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Rxra retinoid X receptor alpha decreases degradation
decreases localization
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein
Tetradecanoylphorbol Acetate results in decreased localization of RXRA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein] 		CTD PMID:12970875 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417 		JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions
increases expression 		ISO Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A4 mRNA] CTD PMID:24211529 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of S100A6 protein CTD PMID:20045496 PMID:24073338 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A8 protein 		CTD PMID:1733233 PMID:20172950 PMID:22359662 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA] 		CTD PMID:1733233 PMID:20045496 PMID:20172950 PMID:22359662 PMID:24073338 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G S100b S100 calcium binding protein B multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] CTD PMID:23541064 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] CTD PMID:15477007 NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCD1 mRNA CTD PMID:37055963 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scly selenocysteine lyase multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCLY protein CTD PMID:30218697 NCBI chr 9:99,337,796...99,358,487
Ensembl chr 9:99,327,873...99,358,487 		JBrowse link
G Scrn1 secernin 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SCRN1 mRNA CTD PMID:31904401 NCBI chr 4:84,962,450...85,024,577
Ensembl chr 4:84,965,751...85,031,205 		JBrowse link
G Sdc1 syndecan 1 multiple interactions
increases secretion
decreases expression 		ISO GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC1 protein
Tetradecanoylphorbol Acetate results in decreased expression of SDC1 protein alternative form 		CTD PMID:19875451 PMID:26852939 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500 		JBrowse link
G Sdc4 syndecan 4 multiple interactions
decreases expression 		ISO GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC4 protein
Tetradecanoylphorbol Acetate results in decreased expression of SDC4 protein alternative form 		CTD PMID:19875451 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
G Sec61g Sec61 translocon subunit gamma multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA CTD PMID:19840844 NCBI chr14:95,113,083...95,119,458
Ensembl chr 9:48,798,504...48,798,710
Ensembl chr14:48,798,504...48,798,710 		JBrowse link
G Sele selectin E multiple interactions
increases expression 		ISO [Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]; adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein] CTD PMID:8780174 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Selenop selenoprotein P multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA CTD PMID:19840844 NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019 		JBrowse link
G Selenos selenoprotein S multiple interactions ISO SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein] CTD PMID:16227999 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:129,070,230...129,077,991 		JBrowse link
G Sell selectin L multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA] CTD PMID:21331654 NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600 		JBrowse link
G Sem1 SEM1 26S proteasome subunit increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of SEM1 mRNA
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of SEM1 mRNA 		CTD PMID:18922899 NCBI chr 4:35,638,306...35,658,462
Ensembl chr 4:35,638,306...35,658,462 		JBrowse link
G Serpinb2 serpin family B member 2 affects expression
increases expression
affects response to substance 		ISO Tetradecanoylphorbol Acetate affects the expression of SERPINB2
Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 protein
SERPINB2 affects the susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:8631129 PMID:16044405 PMID:19945525 NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031 		JBrowse link
G Serpinb9 serpin family B member 9 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 protein CTD PMID:12177049 NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases secretion
increases expression 		ISO
EXP 		[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 protein
Tetradecanoylphorbol Acetate results in increased secretion of SERPINE1 protein
Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA]
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of SERPINE1 protein 		CTD PMID:12409145 PMID:16368122 PMID:18958680 PMID:35001170 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] CTD PMID:15477007 NCBI chr 2:186,421,667...186,426,419
Ensembl chr 2:186,421,636...186,426,833 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP1 mRNA CTD PMID:23519560 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP2 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SFRP2 mRNA CTD PMID:23519560 PMID:31904401 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:171,387,385...171,395,079 		JBrowse link
G Sftpb surfactant protein B increases secretion
multiple interactions 		EXP
ISO 		Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein
Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein] 		CTD PMID:11704537 PMID:14565945 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646 		JBrowse link
G Sftpc surfactant protein C increases secretion
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein
Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein] 		CTD PMID:11704537 PMID:14565945 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475 		JBrowse link
G Sftpd surfactant protein D multiple interactions EXP
ISO 		[Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD protein
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFTPD mRNA 		CTD PMID:9476903 PMID:23519560 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,080,567...17,094,036 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions
increases expression 		EXP
ISO 		Tetradecanoylphorbol Acetate promotes the reaction [11-dehydrocorticosterone results in increased expression of SGK1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cortisone results in increased expression of SGK1 mRNA]
Tetradecanoylphorbol Acetate results in increased expression of SGK1 mRNA 		CTD PMID:16533503 PMID:31068361 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SHANK2 mRNA CTD PMID:16979875 NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:208,598,772...209,018,736 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression
increases phosphorylation
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in increased expression of SHC1 mRNA
Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form] 		CTD PMID:19031421 PMID:19168439 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Siglec5 sialic acid binding Ig-like lectin 5 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SIGLEC6 mRNA CTD PMID:16979875 NCBI chr 1:102,904,705...102,913,281
Ensembl chr 1:102,904,578...102,913,281 		JBrowse link
G Sla src-like adaptor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] CTD PMID:15477007 NCBI chr 7:100,423,467...100,473,840
Ensembl chr 7:100,424,169...100,473,684 		JBrowse link
G Slc17a3 solute carrier family 17 member 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC17A3 mRNA CTD PMID:31904401 NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity 		EXP bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]]; Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Tetradecanoylphorbol Acetate results in decreased activity of SLC19A1 protein 		CTD PMID:17482559 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 multiple interactions
increases activity 		EXP [Tetradecanoylphorbol Acetate co-treated with Propofol] inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of SLC1A1 protein]; Caffeine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SLC1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Nicotine results in decreased activity of SLC1A1 protein] CTD PMID:17382927 PMID:23262392 PMID:23602688 PMID:24355585 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions EXP [phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of GLT-1 protein in cultured astrocytes RGD PMID:28341892 RGD:597978120 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression EXP Tetradecanoylphorbol Acetate results in decreased expression of SLC1A5 protein CTD PMID:21812036 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SLC2A1 mRNA CTD PMID:19000923 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742 		JBrowse link
G Slc35f1 solute carrier family 35, member F1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC35F1 mRNA CTD PMID:31904401 NCBI chr20:32,573,091...32,961,466
Ensembl chr20:32,573,428...32,961,465 		JBrowse link
G Slc38a3 solute carrier family 38, member 3 decreases expression EXP Tetradecanoylphorbol Acetate results in decreased expression of SLC38A3 protein CTD PMID:21812036 NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:117,202,536...117,218,630 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] CTD PMID:15477007 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:31,040,017...31,051,670 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SLC6A3 protein; Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] CTD PMID:22683840 PMID:24101030 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
decreases activity
increases phosphorylation 		EXP TPA decreases activity of Slc6a4 protein in synaptosomes, TPA increases phosphorylation of Slc6a4 protein in synaptosomes
TPA decreases activity of Slc6a4 protein in cultured neurons 		RGD PMID:11113454 PMID:11859926 PMID:12590935 RGD:38456013, RGD:38549589, RGD:38549585 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SLC7A11 mRNA CTD PMID:17200146 PMID:26198647 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions EXP Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of SLC8A1 mRNA] CTD PMID:19244478 NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964 		JBrowse link
G Slit3 slit guidance ligand 3 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLIT3 mRNA CTD PMID:31904401 NCBI chr10:20,075,929...20,660,704
Ensembl chr10:20,076,021...20,660,704 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases expression 		ISO Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form] CTD PMID:20172950 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases methylation 		ISO corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of SMAD3 gene] CTD PMID:32135139 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SMC4 mRNA CTD PMID:19031421 NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:155,550,262...155,581,937 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 multiple interactions ISO SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] CTD PMID:24951586 NCBI chr 1:169,304,772...169,308,615
Ensembl chr 1:169,304,708...169,308,614 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SMPDL3A mRNA CTD PMID:31904401 NCBI chr20:37,679,004...37,701,979
Ensembl chr20:37,678,964...37,704,260 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein] CTD PMID:25656647 NCBI chr 3:176,667,476...176,671,965 JBrowse link
G Snora33 small nucleolar RNA, H/ACA box 33 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SNORA33 mRNA CTD PMID:31068361 NCBI chr10:87,688,990...87,689,121 JBrowse link
G Snora73b small nucleolar RNA, H/ACA box 73b increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SNORA73B mRNA CTD PMID:31068361 NCBI chr 5:149,829,190...149,829,393
Ensembl chr 5:149,829,190...149,829,393 		JBrowse link
G Snord51 small nucleolar RNA, C/D box 51 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SNORD51 mRNA CTD PMID:31068361 NCBI chr 9:72,075,585...72,075,662
Ensembl chr 9:72,075,585...72,075,662 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SOCS2 mRNA CTD PMID:16979875 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions
increases expression 		ISO 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOCS3 protein] CTD PMID:23782265 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression
increases expression 		ISO Tetradecanoylphorbol Acetate promotes the reaction [Glucose deficiency results in decreased expression of and results in increased degradation of SOD1 protein]
[decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD1 protein
Tetradecanoylphorbol Acetate results in decreased expression of SOD1 protein
Tetradecanoylphorbol Acetate results in increased expression of SOD1 protein 		CTD PMID:17309078 PMID:20045496 PMID:20831825 PMID:24073338 PMID:31351099 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
increases activity
increases abundance 		ISO
EXP 		2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOD2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin]; Tetradecanoylphorbol Acetate inhibits the reaction [12-deoxyphorbolphenylacetate-20-acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [thymeleatoxin results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of SOD2 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of SOD2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]
[decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD2 protein; SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene]
[Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein
[Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species] which results in increased abundance of SOD2 		CTD PMID:7564102 PMID:8037686 PMID:8702551 PMID:9067545 PMID:9434740 More... NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SORL1 mRNA CTD PMID:31904401 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:51,238,722...51,401,446 		JBrowse link
G Sox17 SRY-box transcription factor 17 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA CTD PMID:23519560 NCBI chr 5:19,814,345...19,819,859
Ensembl chr 5:19,814,360...19,819,854 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases expression
increases activity 		ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of SP1 protein; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter]
Tetradecanoylphorbol Acetate results in increased expression of SP1 mRNA
Tetradecanoylphorbol Acetate results in increased activity of SP1 protein 		CTD PMID:10669635 PMID:15978937 PMID:24244623 PMID:27351882 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Sp110 SP110 nuclear body protein multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SP110 mRNA CTD PMID:31904401 NCBI chr 9:93,648,574...93,673,476
Ensembl chr 9:93,648,575...93,670,659 		JBrowse link
G Spag5 sperm associated antigen 5 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SPAG5 mRNA CTD PMID:19031421 NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,696,466...63,714,811 		JBrowse link
G Spi1 Spi-1 proto-oncogene increases activity ISO Tetradecanoylphorbol Acetate results in increased activity of SPI1 protein CTD PMID:18418899 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression 		ISO [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SPP1 mRNA; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA
Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein 		CTD PMID:11426586 PMID:16979875 PMID:17360982 PMID:19840844 PMID:31904401 More... NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Sprr1a small proline-rich protein 1A increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA
Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPRR1A protein 		CTD PMID:8617999 PMID:10866668 PMID:11485391 NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991 		JBrowse link
G Sprr1b small proline-rich protein 1B increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SPRR1B mRNA CTD PMID:11485391 NCBI chr 2:180,704,457...180,706,355
Ensembl chr 2:180,704,457...180,706,355 		JBrowse link
G Sprr2a small proline rich protein 2A multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of SPRR2A mRNA
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPRR2H mRNA] 		CTD PMID:18922899 PMID:32135139 NCBI chr 2:180,511,568...180,511,840 JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
increases expression 		ISO corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]
AG 1879 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein] 		CTD PMID:20660715 PMID:26100520 PMID:26513295 PMID:28527916 PMID:34144024 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases cleavage
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein
dorsomorphin promotes the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein] 		CTD PMID:29499335 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Srpra SRP receptor subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA CTD PMID:15477007 NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:41,818,229...41,824,280 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
increases expression 		ISO [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone; [Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [[Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAR protein]
Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA; Tetradecanoylphorbol Acetate results in increased expression of STAR protein 		CTD PMID:18755854 PMID:18787026 PMID:19282384 PMID:21047949 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
affects localization
multiple interactions
increases expression 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein
Tetradecanoylphorbol Acetate affects the localization of STAT3 protein
[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]
Tetradecanoylphorbol Acetate results in increased expression of STAT3
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]] 		CTD PMID:20523355 PMID:22986104 PMID:24496235 PMID:25128825 PMID:26100520 More... NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A increases phosphorylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein
CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein] 		CTD PMID:20523355 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein CTD PMID:26091108 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions
decreases phosphorylation 		ISO corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein] CTD PMID:26513295 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Stmn1 stathmin 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of STMN1 mRNA CTD PMID:19000923 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Sts steroid sulfatase multiple interactions
increases expression 		ISO prolinedithiocarbamate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Estradiol]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of STS protein
Tetradecanoylphorbol Acetate results in increased expression of STS mRNA 		CTD PMID:26220752 PMID:31217279 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA CTD PMID:19840844 NCBI chr10:101,270,899...101,283,458
Ensembl chr10:101,270,900...101,283,938
Ensembl chr 5:101,270,900...101,283,938 		JBrowse link
G Syn1 synapsin I multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA CTD PMID:19840844 NCBI chr  X:3,725,745...3,780,940
Ensembl chr  X:3,725,714...3,780,938 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein multiple interactions
affects localization 		ISO Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of SYNCRIP protein] CTD PMID:19331829 NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:98,282,358...98,315,386 		JBrowse link
G Taf15 TATA-box binding protein associated factor 15 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TAF15 mRNA CTD PMID:16979875 NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,770,430...68,802,458 		JBrowse link
G Tagln transgelin decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of TAGLN mRNA CTD PMID:15380616 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563 		JBrowse link
G Tasp1 taspase 1 multiple interactions
increases methylation 		ISO corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of TASP1 gene] CTD PMID:32135139 NCBI chr 3:147,630,092...147,861,710
Ensembl chr 3:147,630,092...147,861,654 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein] CTD PMID:9398635 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions ISO [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA] CTD PMID:22398747 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
G Terf1 telomeric repeat binding factor 1 multiple interactions ISO [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA CTD PMID:26330309 NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:8,226,345...8,255,753 		JBrowse link
G Terf2 telomeric repeat binding factor 2 increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA
2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA] 		CTD PMID:26330309 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Tert telomerase reverse transcriptase decreases expression
decreases activity
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in decreased expression of TERT mRNA
Tetradecanoylphorbol Acetate results in decreased activity of TERT protein
2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein] 		CTD PMID:26330309 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tfap2a transcription factor AP-2 alpha multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]] CTD PMID:21499124 PMID:21951556 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression 		ISO 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein] CTD PMID:22643241 PMID:31217279 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
G Tfrc transferrin receptor multiple interactions
decreases expression
increases expression 		ISO
EXP 		catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]
Tetradecanoylphorbol Acetate results in decreased expression of TFRC protein
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TFRC protein
Tetradecanoylphorbol Acetate results in increased expression of TFRC mRNA 		CTD PMID:9766631 PMID:12749906 PMID:19000923 PMID:30218697 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions
increases secretion 		ISO ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of TGFA protein CTD PMID:15066986 PMID:28703301 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases activity
increases expression
affects response to substance 		ISO [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGFB1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB1 mRNA; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]
Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein
Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of TGFB1 protein
TGFB1 affects the susceptibility to Tetradecanoylphorbol Acetate
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] 		CTD PMID:8148055 PMID:10381133 PMID:11728381 PMID:15802798 PMID:16979875 More... NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB2 mRNA CTD PMID:16979875 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgm1 transglutaminase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TGM1 mRNA CTD PMID:10866668 PMID:11485391 NCBI chr15:33,160,985...33,175,632
Ensembl chr15:33,160,987...33,174,463 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions
decreases expression 		ISO Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein]
Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein 		CTD PMID:22986104 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240 		JBrowse link
G Th tyrosine hydroxylase increases expression
multiple interactions 		EXP
ISO 		Tetradecanoylphorbol Acetate results in increased expression of TH mRNA
[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TH protein 		CTD PMID:18992715 PMID:24101030 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thbd thrombomodulin multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THBD mRNA CTD PMID:31904401 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA CTD PMID:19840844 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thbs2 thrombospondin 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA CTD PMID:19840844 PMID:23519560 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918 		JBrowse link
G Thpo thrombopoietin multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of THPO mRNA CTD PMID:16979875 Ensembl chr11:93,686,834...93,693,320 JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THY1 mRNA CTD PMID:31904401 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TIMM17A mRNA CTD PMID:16979875 NCBI chr13:49,282,918...49,296,363
Ensembl chr13:49,282,918...49,307,904 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
increases expression 		ISO Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] CTD PMID:11414687 PMID:18155510 PMID:20599481 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions
increases expression 		ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA
Tetradecanoylphorbol Acetate results in increased expression of TIMP2 protein 		CTD PMID:19840844 PMID:19969058 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TLR2 protein CTD PMID:28720485 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
increases expression 		ISO [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] CTD PMID:23680697 PMID:26187476 PMID:28720485 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr6 toll-like receptor 6 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TLR6 mRNA CTD PMID:16979875 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,698,751...43,740,462 		JBrowse link
G Tnc tenascin C multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNC mRNA CTD PMID:16979875 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
affects response to substance 		ISO
EXP 		1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of TNF protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNF mRNA; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of TNF protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; butein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein]; chromic acid inhibits the reaction [[Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chromic chloride inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Doxycycline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; hispidulin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Ionomycin inhibits the reaction [[N-(4-hydroxyphenyl)arachidonylamide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; mancozeb inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Ozone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]
Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein
TNF protein affects the susceptibility to Tetradecanoylphorbol Acetate
[Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]
12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; bolinaquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased expression of and results in increased secretion of TNF protein]]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] 		CTD PMID:1371491 PMID:9122163 PMID:9584910 PMID:9628260 PMID:10072544 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression
multiple interactions
increases expression
increases activity 		ISO Tetradecanoylphorbol Acetate results in decreased expression of TNFAIP3 mRNA
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TNFAIP3 protein]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] 		CTD PMID:15451058 PMID:20438634 PMID:21035309 PMID:21873647 PMID:31068361 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions
increases expression
decreases expression 		ISO 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; KB R8301 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]
Tetradecanoylphorbol Acetate results in decreased expression of TNFRSF1A protein 		CTD PMID:9870925 PMID:11882518 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions
increases expression 		ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein] CTD PMID:10072544 PMID:15477007 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of TNFRSF21 mRNA CTD PMID:18353537 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 multiple interactions
increases expression 		EXP Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Mercuric Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Staurosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] CTD PMID:9766631 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:171,889,117...171,892,616 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TNFRSF8 mRNA CTD PMID:9933429 NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:162,406,387...162,451,620 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNFRSF9 mRNA CTD PMID:16979875 NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:166,664,494...166,690,831 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] CTD PMID:21603612 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnfsf11 TNF superfamily member 11 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TNFSF11 mRNA CTD PMID:17306214 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf8 TNF superfamily member 8 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TNFSF8 mRNA CTD PMID:9933429 NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:82,266,436...82,292,858 		JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions ISO chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNI3 protein] CTD PMID:12003851 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions ISO chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNT2 protein] CTD PMID:12003851 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA CTD PMID:19840844 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Tp53 tumor protein p53 decreases expression
increases phosphorylation
multiple interactions 		ISO
EXP 		Tetradecanoylphorbol Acetate results in decreased expression of TP53 protein
Tetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein
Tetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of TP53 protein] 		CTD PMID:8076368 PMID:8927716 PMID:10910098 PMID:15542774 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpd52 tumor protein D52 decreases expression
increases expression 		ISO Tetradecanoylphorbol Acetate results in decreased expression of TPD52 mRNA
Tetradecanoylphorbol Acetate results in increased expression of TPD52 mRNA 		CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TPX2 mRNA CTD PMID:19031421 NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] CTD PMID:15477007 PMID:21035309 NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions
decreases expression 		ISO hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA]; hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]
Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein 		CTD PMID:30090394 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP
ISO 		TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]
Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] 		CTD PMID:10889193 NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762 		JBrowse link
G Trhde thyrotropin-releasing hormone degrading enzyme multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TRHDE mRNA CTD PMID:16979875 NCBI chr 7:51,829,473...52,236,843
Ensembl chr 7:51,832,111...52,236,843 		JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] CTD PMID:15477007 NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:44,274,762...44,299,094 		JBrowse link
G Trim7 tripartite motif-containing 7 multiple interactions ISO TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] CTD PMID:25851810 NCBI chr10:33,706,614...33,722,609
Ensembl chr10:33,706,614...33,722,609 		JBrowse link
G Trnp1 TMF1-regulated nuclear protein 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of TRNP1 mRNA CTD PMID:31904401 NCBI chr 5:150,990,312...150,997,148
Ensembl chr 5:150,989,973...150,997,277 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of TRPA1 mRNA CTD PMID:36847817 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:9,163,060...9,217,325 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of TRPC3 mRNA CTD PMID:19244478 NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases expression
increases activity
increases localization 		ISO
EXP 		Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]
Tetradecanoylphorbol Acetate results in increased expression of TRPV1 mRNA
Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein
Tetradecanoylphorbol Acetate results in increased localization of TRPV1 protein
bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate affects the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lidocaine results in increased activity of TRPV1 protein]
RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the activity of TRPV1 protein; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]] 		CTD PMID:11140687 PMID:15363968 PMID:16319926 PMID:17913835 PMID:18172555 More... NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Tsc2 TSC complex subunit 2 increases phosphorylation
multiple interactions 		EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein
U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein] 		CTD PMID:15757502 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600 		JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
increases secretion 		ISO Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA
phorbol 12-myristate 13-acetate increases expression of Tslp protein in keratinocytes
Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein
Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA; Tetradecanoylphorbol Acetate results in increased expression of TSLP protein
FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein]
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein] 		CTD
RGD		 PMID:18049884 PMID:24131540 PMID:29462589 PMID:35717073 PMID:29310423 RGD:38549374 NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420 		JBrowse link
G Tspo translocator protein multiple interactions
increases expression 		ISO PPARA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSPO mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSPO mRNA] CTD PMID:22205965 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:116,600,210...116,610,460 		JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA CTD PMID:19840844 NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 multiple interactions ISO [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TWF2 protein CTD PMID:30218697 NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:115,723,970...115,737,025 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions
increases expression 		ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA
Tetradecanoylphorbol Acetate results in increased expression of TXN mRNA 		CTD PMID:19840844 PMID:24632381 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TXNRD1 mRNA CTD PMID:12949356 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tymp thymidine phosphorylase multiple interactions
increases expression
increases activity 		ISO Aspirin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]
Tetradecanoylphorbol Acetate results in increased activity of TYMP protein 		CTD PMID:14573775 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003 		JBrowse link
G Tyms thymidylate synthetase increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of TYMS mRNA CTD PMID:19031421 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097 		JBrowse link
G Tyr tyrosinase multiple interactions ISO [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of TYR protein CTD PMID:20691676 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] CTD PMID:15477007 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA CTD PMID:19840844 NCBI chr12:36,899,673...36,905,275
Ensembl chr12:36,900,127...36,905,275 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 decreases expression ISO Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 protein CTD PMID:15964557 NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792 		JBrowse link
G Ulbp1 UL16 binding protein 1 multiple interactions ISO Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride results in increased expression of ULBP1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib results in increased expression of ULBP1 mRNA] CTD PMID:21499124 PMID:21951556 NCBI chr 1:3,506,106...3,527,982 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO [maslinic acid analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of ULK1 protein CTD PMID:26513295 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone increases methylation
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene] 		CTD PMID:32135139 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:99,783,158...99,853,906 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of USP18 mRNA CTD PMID:31904401 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:156,143,815...156,171,292 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein] CTD PMID:12615669 PMID:21035309 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vdr vitamin D receptor multiple interactions
increases expression 		ISO
EXP 		Tetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein]
Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA]
Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA; Tetradecanoylphorbol Acetate results in increased expression of VDR protein 		CTD PMID:9348195 PMID:11504768 PMID:20006981 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion
increases expression
decreases expression 		ISO
EXP 		5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein modified form; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VEGFA mRNA; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; eriodictyol affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]
[Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]
[Norepinephrine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] 		CTD PMID:8537383 PMID:9743532 PMID:10788502 PMID:11158990 PMID:11214823 More... NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]
[sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of VIM protein; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein] 		CTD PMID:15477007 PMID:25656647 PMID:28108223 PMID:35364107 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VIPR2 mRNA CTD PMID:16979875 NCBI chr 6:143,139,672...143,213,609
Ensembl chr 6:143,144,523...143,213,609 		JBrowse link
G Vit vitrin multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of VIT mRNA CTD PMID:23519560 NCBI chr 6:22,198,095...22,317,758
Ensembl chr 6:22,198,006...22,317,733 		JBrowse link
G Vsnl1 visinin-like 1 multiple interactions
decreases response to substance 		ISO VSNL1 protein results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]
VSNL1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate 		CTD PMID:20419170 NCBI chr 6:39,757,721...39,878,556
Ensembl chr 6:39,757,722...39,878,556 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions
increases activity 		ISO Allopurinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:3677084 PMID:22036979 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
G Yy1 YY1 transcription factor increases expression
multiple interactions 		ISO Tetradecanoylphorbol Acetate results in increased expression of YY1 protein
[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of YY1 protein 		CTD PMID:32363662 NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:133,471,562...133,497,257 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ZC3H12A mRNA CTD PMID:31068361 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:142,661,199...142,669,985 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB1 mRNA
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein] 		CTD PMID:11893416 PMID:16979875 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB2 mRNA CTD PMID:16979875 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:49,624,028...49,754,323 		JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ZFP36 mRNA CTD PMID:19945525 PMID:31068361 NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:92,796,628...92,799,108 		JBrowse link
G Znf235 zinc finger protein 235 multiple interactions ISO [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZNF235 mRNA CTD PMID:16979875 NCBI chr 1:88,826,910...88,836,360
Ensembl chr 1:88,827,737...88,836,359 		JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Tetradecanoylphorbol Acetate results in increased expression of ZWINT mRNA CTD PMID:19031421 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203 		JBrowse link
Polyoxyethylene dioleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 multiple interactions ISO dioleoyl ethylene glycol inhibits the reaction [Phosphatidylinositols results in increased expression of APOA1 protein] CTD PMID:19013290 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
rac-1-monolauroylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO 1-monomyristin inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ereg epiregulin increases expression ISO palmitate increases expression of Ereg mRNA in myofibroblast cells RGD PMID:23805328 RGD:39457689 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
simvastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Simvastatin results in decreased expression of A2M mRNA CTD PMID:16414398 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression
increases expression 		ISO
EXP 		Simvastatin results in decreased expression of ABCA1; Simvastatin results in decreased expression of ABCA1 mRNA
Simvastatin results in increased expression of ABCA1 mRNA; Simvastatin results in increased expression of ABCA1 protein 		CTD PMID:16282522 PMID:18270459 PMID:19383813 PMID:19461118 PMID:21241519 More... NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity 		ISO
EXP 		Simvastatin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Simvastatin results in decreased expression of ABCB11 mRNA
Simvastatin results in decreased activity of ABCB11 protein 		CTD PMID:20829430 PMID:23956101 PMID:24014644 PMID:27765674 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport
decreases activity
affects response to substance 		ISO ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Simvastatin]; Simvastatin analog inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]
ABCB1 protein results in increased transport of Simvastatin
Simvastatin analog results in decreased activity of ABCB1 protein
ABCB1 polymorphism affects the susceptibility to Simvastatin 		CTD PMID:15616150 PMID:16321621 PMID:19802823 PMID:19891551 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression 		ISO
EXP 		Simvastatin results in increased expression of ABCB4 mRNA
Simvastatin results in decreased expression of ABCB4 mRNA 		CTD PMID:21241519 PMID:27765674 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression
affects response to substance
decreases activity 		EXP
ISO 		ABCC2 protein binds to and results in increased uptake of Simvastatin analog; Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]; Simvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]
Simvastatin results in decreased expression of ABCC2 mRNA
ABCC2 polymorphism affects the susceptibility to Simvastatin
Simvastatin analog results in decreased activity of ABCC2 protein 		CTD PMID:15616150 PMID:22186618 PMID:23562342 PMID:27765674 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
increases nitrosation 		ISO artemisinin inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]; parthenolide inhibits the reaction [Simvastatin results in increased nitrosation of ABCC3 protein]; Simvastatin promotes the reaction [Doxorubicin results in increased nitrosation of ABCC3 protein] CTD PMID:18463201 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Simvastatin results in decreased expression of ABCG1 mRNA CTD PMID:19383813 PMID:22120639 NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Simvastatin results in increased expression of ABCG5 mRNA CTD PMID:21241519 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression EXP Simvastatin results in decreased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression
multiple interactions 		EXP Simvastatin results in decreased expression of ACAA2 mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of ACAA2 mRNA 		CTD PMID:25055962 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression EXP Simvastatin results in increased expression of ACACB mRNA CTD PMID:12056585 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G Acan aggrecan multiple interactions
increases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of ACAN mRNA]; NOG inhibits the reaction [Simvastatin results in increased expression of ACAN mRNA] CTD PMID:18628692 PMID:19912653 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Simvastatin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression
multiple interactions 		EXP
ISO 		Simvastatin results in decreased expression of ACTA2 protein
Simvastatin inhibits the reaction [TGFB1 results in increased expression of ACTA2 mRNA] 		CTD PMID:15677772 PMID:15855201 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Actb actin, beta increases expression EXP Simvastatin results in increased expression of ACTB mRNA CTD PMID:25055962 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Actn4 actinin alpha 4 increases expression ISO Simvastatin results in increased expression of ACTN4 mRNA CTD PMID:16710349 NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO
EXP 		Simvastatin promotes the reaction [Lipopolysaccharides results in increased expression of ADIPOQ mRNA]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of ADIPOQ protein]
carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein]]; Simvastatin inhibits the reaction [Poloxamer results in decreased secretion of ADIPOQ protein] 		CTD PMID:17641834 PMID:29071762 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adora2b adenosine A2B receptor multiple interactions EXP Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of ADORA2B mRNA]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of ADORA2B protein] CTD PMID:33774062 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091 		JBrowse link
G Adrb1 adrenoceptor beta 1 increases expression ISO Simvastatin results in increased expression of ADRB1 mRNA; Simvastatin results in increased expression of ADRB1 protein CTD PMID:19262002 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Afp alpha-fetoprotein increases expression ISO Simvastatin results in increased expression of AFP mRNA CTD PMID:10365819 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein]
Simvastatin results in decreased expression of AGER protein 		CTD PMID:17038636 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Agt angiotensinogen multiple interactions
decreases expression 		ISO
EXP 		[Valsartan co-treated with Simvastatin] inhibits the reaction [AGT protein results in increased expression of KLF10 mRNA]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; Simvastatin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [AGT results in increased activity of RAC1 protein]; Simvastatin promotes the reaction [Glucose promotes the reaction [AGT protein results in increased expression of PTGS2 mRNA]]
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]]; Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of PXN protein]; Simvastatin inhibits the reaction [CTF1 results in increased expression of AGT mRNA]
Simvastatin results in decreased expression of AGT mRNA 		CTD PMID:17513949 PMID:18400235 PMID:18475152 PMID:19100119 PMID:19225232 More... NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO Simvastatin results in decreased expression of AGTR1 mRNA CTD PMID:17513949 PMID:18475152 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Simvastatin results in increased expression of AKR1C1 mRNA CTD PMID:17428261 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression ISO Simvastatin results in decreased expression of AKR1C3 mRNA CTD PMID:18192897 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression EXP Simvastatin results in decreased expression of AKR1D1 mRNA CTD PMID:25055962 NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
decreases phosphorylation
increases phosphorylation
multiple interactions
decreases activity 		ISO
EXP 		Simvastatin results in decreased expression of AKT1 mRNA; Simvastatin results in decreased expression of AKT1 protein
Simvastatin results in decreased phosphorylation of AKT1 protein
Simvastatin results in increased phosphorylation of AKT1 protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [IGF1 results in increased activity of AKT1 protein]
Simvastatin results in decreased activity of AKT1 protein
Simvastatin inhibits the reaction [Glucose results in decreased expression of AKT1 protein modified form]; Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [Smoke analog results in increased phosphorylation of AKT1 protein]; Simvastatin results in increased phosphorylation of and results in increased activity of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin promotes the reaction [[Nifedipine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in increased phosphorylation of and results in increased activity of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; [Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein; [Simvastatin co-treated with Metformin] results in decreased phosphorylation of AKT1 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of AKT1 mRNA]; Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]; Simvastatin promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of AKT1 protein]; Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of AKT1 protein]; Simvastatin results in increased phosphorylation of and results in increased activity of AKT1 protein; Wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]]; Wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Nifedipine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein]] 		CTD PMID:12438947 PMID:17327694 PMID:17335931 PMID:18004065 PMID:18031796 More... NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO Simvastatin results in increased expression of ALDH3A1 mRNA CTD PMID:17428261 NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151 		JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA CTD PMID:28263720 NCBI chr 6:28,631,431...29,351,321
Ensembl chr 6:28,632,197...29,349,721 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO Simvastatin results in increased expression of ALOX5AP mRNA CTD PMID:17183729 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038 		JBrowse link
G Alpi alkaline phosphatase, intestinal increases expression ISO Simvastatin results in increased expression of ALPI mRNA CTD PMID:14973129 NCBI chr 9:95,221,314...95,224,780
Ensembl chr 9:95,221,314...95,224,780 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression
multiple interactions
affects expression 		ISO Simvastatin results in increased expression of ALPL mRNA
Hydroxychloroquine affects the reaction [Simvastatin affects the expression of ALPL mRNA] 		CTD PMID:20417880 PMID:28975700 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Angpt1 angiopoietin 1 increases expression EXP Simvastatin results in increased expression of ANGPT1; Simvastatin results in increased expression of ANGPT1 mRNA; Simvastatin results in increased expression of ANGPT1 protein CTD PMID:18544044 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Angpt2 angiopoietin 2 multiple interactions EXP Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein] CTD PMID:20821229 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP Simvastatin results in decreased expression of ANGPTL3 mRNA CTD PMID:25055962 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Simvastatin results in increased expression of ANGPTL4 mRNA CTD PMID:19262002 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression EXP Simvastatin results in increased expression of ANKRA2 mRNA CTD PMID:25055962 NCBI chr 2:31,347,158...31,358,002
Ensembl chr 2:31,347,090...31,364,394 		JBrowse link
G Anpep alanyl aminopeptidase, membrane increases expression ISO Simvastatin results in increased expression of ANPEP mRNA CTD PMID:19262002 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101 		JBrowse link
G Anxa1 annexin A1 increases expression ISO Simvastatin results in increased expression of ANXA1 protein CTD PMID:14973129 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Anxa3 annexin A3 decreases expression ISO Simvastatin results in decreased expression of ANXA3 mRNA
Simvastatin results in decreased expression of ANXA3 protein 		CTD PMID:14973129 PMID:17428261 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of AOC1 mRNA] CTD PMID:16373842 NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704 		JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP Simvastatin results in decreased expression of APMAP protein CTD PMID:20217863 NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
decreases expression
increases expression 		ISO
EXP 		MTHFR gene mutant form inhibits the reaction [Simvastatin results in increased expression of APOA1 protein]
Simvastatin results in decreased expression of APOA1 mRNA; Simvastatin results in decreased expression of APOA1 protein
[Niacin co-treated with Ezetimibe co-treated with Simvastatin] results in increased expression of APOA1 protein; [Simvastatin co-treated with Ezetimibe] results in increased expression of APOA1 protein; Homocysteine inhibits the reaction [Simvastatin results in increased expression of APOA1 mRNA]; Homocysteine inhibits the reaction [Simvastatin results in increased expression of APOA1 protein]; Niacin promotes the reaction [[Simvastatin co-treated with Ezetimibe] results in increased expression of APOA1 protein]; Simvastatin results in increased expression of and results in increased secretion of APOA1 protein
Simvastatin results in increased expression of APOA1 mRNA; Simvastatin results in increased expression of APOA1 protein
Polystyrenes analog promotes the reaction [Simvastatin results in increased expression of APOA1 mRNA]; Simvastatin promotes the reaction [Polystyrenes analog results in increased expression of APOA1 mRNA] 		CTD PMID:8289597 PMID:8461338 PMID:12048122 PMID:12633795 PMID:18270459 More... NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP Simvastatin results in decreased expression of APOA2 mRNA CTD PMID:25055962 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions
decreases expression
increases expression 		ISO
EXP 		Simvastatin inhibits the reaction [[APOA4 protein co-treated with CBS protein] affects the abundance of Nitrogen Compounds]; Simvastatin promotes the reaction [[APOA4 protein co-treated with CBS protein] affects the expression of CAV1 protein]
Simvastatin results in decreased expression of APOA4 mRNA; Simvastatin results in decreased expression of APOA4 protein
Polystyrenes analog promotes the reaction [Simvastatin results in decreased expression of APOA4 protein]; Simvastatin promotes the reaction [Polystyrenes analog results in decreased expression of APOA4 protein]
Simvastatin results in increased expression of APOA4 protein 		CTD PMID:8289597 PMID:8461338 PMID:18224302 PMID:25055962 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Apob apolipoprotein B multiple interactions
decreases expression
decreases secretion
affects response to substance 		ISO
EXP 		[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB; [Niacin co-treated with Simvastatin] results in decreased expression of APOB protein; HMGCR polymorphism promotes the reaction [[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB]
Simvastatin results in decreased expression of APOB protein
Simvastatin results in decreased secretion of APOB protein
Simvastatin results in decreased expression of APOB mRNA; Simvastatin results in decreased expression of APOB protein
Simvastatin promotes the reaction [Polystyrenes analog results in decreased expression of APOB protein]
APOB polymorphism affects the susceptibility to Simvastatin 		CTD PMID:1627634 PMID:8289597 PMID:8461338 PMID:9512650 PMID:10498134 More... NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP Simvastatin results in decreased expression of APOC1 mRNA CTD PMID:25055962 NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155 		JBrowse link
G Apoc3 apolipoprotein C3 decreases expression EXP Simvastatin results in decreased expression of APOC3 mRNA CTD PMID:25055962 NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679 		JBrowse link
G Apoe apolipoprotein E decreases expression
affects response to substance
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of APOE; Simvastatin results in decreased expression of APOE mRNA
Simvastatin results in decreased expression of APOE mRNA; Simvastatin results in decreased expression of APOE protein
APOE polymorphism affects the susceptibility to Simvastatin
Polystyrenes analog inhibits the reaction [Simvastatin results in decreased expression of APOE protein]
APOE affects the susceptibility to Simvastatin 		CTD PMID:8289597 PMID:8461338 PMID:11849659 PMID:11947894 PMID:12901521 More... NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apof apolipoprotein F decreases expression EXP Simvastatin results in decreased expression of APOF mRNA CTD PMID:25055962 NCBI chr 7:1,285,222...1,286,659
Ensembl chr 7:1,285,222...1,286,659 		JBrowse link
G Apom apolipoprotein M decreases expression
increases expression
multiple interactions 		ISO Simvastatin results in decreased expression of APOM mRNA
Simvastatin results in increased expression of APOM mRNA; Simvastatin results in increased expression of APOM protein
T0901317 inhibits the reaction [Simvastatin results in increased expression of APOM mRNA]; T0901317 inhibits the reaction [Simvastatin results in increased expression of APOM protein]; Ursodeoxycholic Acid inhibits the reaction [Simvastatin results in increased expression of APOM mRNA]; Ursodeoxycholic Acid inhibits the reaction [Simvastatin results in increased expression of APOM protein] 		CTD PMID:21729290 PMID:22160096 NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218 		JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases activity 		ISO
EXP 		oblimersen inhibits the reaction [Simvastatin results in decreased activity of APP protein alternative form]; Simvastatin inhibits the reaction [APP protein alternative form results in decreased expression of CASP3 protein]; Simvastatin inhibits the reaction [APP protein alternative form results in increased activity of CASP3 protein]
Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] 		CTD PMID:17241114 PMID:28734741 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Simvastatin results in decreased expression of ARHGAP29 mRNA CTD PMID:17428261 NCBI chr 2:212,744,626...212,816,710
Ensembl chr 2:212,755,803...212,986,729 		JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO Simvastatin results in increased expression of ARHGAP4 mRNA CTD PMID:14630613 NCBI chr  X:156,787,566...156,802,841
Ensembl chr  X:156,783,776...156,802,450 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO Simvastatin results in increased expression of ARHGEF2 mRNA CTD PMID:14630613 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:176,358,904...176,417,646 		JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP Simvastatin results in decreased expression of ASS1 mRNA CTD PMID:16414398 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627 		JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation EXP Simvastatin results in increased phosphorylation of ATF2 protein CTD PMID:15488325 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Simvastatin results in increased expression of ATF3 mRNA CTD PMID:17428261 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Atf6 activating transcription factor 6 increases expression EXP Simvastatin results in increased expression of ATF6 mRNA; Simvastatin results in increased expression of ATF6 protein CTD PMID:18807172 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Simvastatin results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:20499237 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 increases expression EXP Simvastatin results in increased expression of ATP2A2 mRNA; Simvastatin results in increased expression of ATP2A2 protein CTD PMID:15916736 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 increases expression ISO Simvastatin results in increased expression of ATP6V1E1 mRNA CTD PMID:19262002 NCBI chr 4:155,694,534...155,716,660
Ensembl chr 4:155,694,534...155,716,678 		JBrowse link
G Aurka aurora kinase A decreases expression ISO Simvastatin results in decreased expression of AURKA mRNA CTD PMID:17428261 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771 		JBrowse link
G Axin2 axin 2 affects expression EXP Simvastatin affects the expression of AXIN2 mRNA CTD PMID:19968183 NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575 		JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO Simvastatin results in decreased expression of AXL mRNA CTD PMID:17428261 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases phosphorylation 		ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein]
IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein] 		CTD PMID:12438947 PMID:27734117 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
increases expression 		ISO
EXP 		Simvastatin affects the localization of BAX protein
Simvastatin results in increased expression of BAX protein
Simvastatin results in increased expression of BAX mRNA
Simvastatin results in increased expression of BAX mRNA; Simvastatin results in increased expression of BAX protein 		CTD PMID:12557325 PMID:17901590 PMID:20045437 PMID:25300705 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
affects localization 		ISO Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]; pifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 mRNA]; pifithrin inhibits the reaction [Simvastatin results in increased expression of BBC3 protein]
Simvastatin results in increased expression of BBC3 mRNA; Simvastatin results in increased expression of BBC3 protein
Simvastatin affects the localization of BBC3 protein 		CTD PMID:17428261 PMID:20045437 PMID:21199873 PMID:37956312 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of BCL2 mRNA]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; Simvastatin promotes the reaction [NFATC3 protein binds to BCL2 promoter]
Simvastatin results in decreased expression of BCL2 protein
Simvastatin results in increased expression of BCL2 mRNA; Simvastatin results in increased expression of BCL2 protein
Simvastatin results in decreased expression of BCL2 mRNA; Simvastatin results in decreased expression of BCL2 protein 		CTD PMID:17241114 PMID:17277159 PMID:17901590 PMID:18031796 PMID:18521906 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]
Simvastatin results in decreased expression of BCL2L1 protein 		CTD PMID:17277159 PMID:18521906 PMID:20060890 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions 		EXP Simvastatin results in increased expression of BDNF
Simvastatin promotes the reaction [Lipopolysaccharides results in increased expression of BDNF mRNA] 		CTD PMID:18047562 PMID:20851742 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression
multiple interactions
increases secretion 		ISO
EXP 		Simvastatin results in increased expression of BGLAP; Simvastatin results in increased expression of BGLAP mRNA
Simvastatin results in increased expression of BGLAP; Simvastatin results in increased expression of BGLAP mRNA; Simvastatin results in increased expression of BGLAP protein
CTNNB1 mutant form inhibits the reaction [Simvastatin results in increased expression of BGLAP protein]; DKK1 inhibits the reaction [Simvastatin results in increased expression of BGLAP mRNA]
[Simvastatin co-treated with Dexamethasone] results in increased expression of BGLAP
Simvastatin results in increased secretion of BGLAP protein 		CTD PMID:12914771 PMID:14601315 PMID:14973129 PMID:15953866 PMID:17252541 More... NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA CTD PMID:28263720 NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC2 mRNA]; Simvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC2 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]
Simvastatin results in decreased expression of BIRC2 protein 		CTD PMID:17277159 PMID:18521906 PMID:19343037 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO Simvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC3 mRNA]; Simvastatin inhibits the reaction [Homocysteine results in decreased expression of BIRC3 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC3 protein] CTD PMID:17277159 PMID:19343037 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression 		ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Simvastatin results in decreased expression of BIRC5 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]; Simvastatin promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of BIRC5 protein]
Simvastatin results in decreased expression of BIRC5 mRNA; Simvastatin results in decreased expression of BIRC5 protein 		CTD PMID:17277159 PMID:20464445 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmp1 bone morphogenetic protein 1 increases expression EXP Simvastatin results in increased expression of BMP1 mRNA CTD PMID:12963647 NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases secretion
increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased secretion of BMP2 protein
Simvastatin results in increased expression of BMP2 mRNA; Simvastatin results in increased expression of BMP2 protein
Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of BMP2 mRNA]
Simvastatin results in increased expression of BMP2; Simvastatin results in increased expression of BMP2 mRNA
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; Simvastatin inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD1 protein]]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD5 protein]]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD9 protein]]; Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]] 		CTD PMID:10814523 PMID:11162604 PMID:12914771 PMID:16470222 PMID:17252541 More... NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 affects expression
increases stability
increases expression 		ISO Simvastatin affects the expression of BMPR2 mRNA
Simvastatin results in increased stability of BMPR2 mRNA
Simvastatin results in increased expression of BMPR2 protein 		CTD PMID:16297860 NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Simvastatin results in increased expression of BNIP3 mRNA CTD PMID:17428261 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression EXP Simvastatin results in decreased expression of C5AR1 mRNA CTD PMID:16414398 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
decreases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CACNA1C mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CACNA1C protein]
Simvastatin results in decreased expression of CACNA1C mRNA; Simvastatin results in decreased expression of CACNA1C protein 		CTD PMID:19791473 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions
decreases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CACNA1H mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CACNA1H protein]
Simvastatin results in decreased expression of CACNA1H mRNA; Simvastatin results in decreased expression of CACNA1H protein 		CTD PMID:19791473 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771 		JBrowse link
G Calb1 calbindin 1 multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in decreased expression of CALB1 mRNA] CTD PMID:16373842 NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160 		JBrowse link
G Calb2 calbindin 2 decreases expression EXP Simvastatin results in decreased expression of CALB2 protein CTD PMID:20217863 NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952 		JBrowse link
G Cald1 caldesmon 1 decreases expression ISO Simvastatin results in decreased expression of CALD1 mRNA; Simvastatin results in decreased expression of CALD1 protein CTD PMID:14630613 NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085 		JBrowse link
G Calml3 calmodulin-like 3 increases expression ISO Simvastatin results in increased expression of CALML3 mRNA CTD PMID:17428261 NCBI chr17:71,329,438...71,333,068
Ensembl chr17:71,319,943...71,335,682 		JBrowse link
G Capn1 calpain 1 increases expression ISO Simvastatin results in increased expression of CAPN1 mRNA CTD PMID:18664198 PMID:19253821 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 decreases expression EXP Simvastatin results in decreased expression of CAPZA1 protein CTD PMID:20217863 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:195,008,039...195,053,100 		JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 decreases expression EXP Simvastatin results in decreased expression of CAPZA2 protein CTD PMID:20217863 NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938 		JBrowse link
G Casp1 caspase 1 decreases activity
multiple interactions 		EXP Simvastatin results in decreased activity of CASP1 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein]]; Simvastatin inhibits the reaction [Acetic Acid results in increased expression of CASP1 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CASP1 protein] 		CTD PMID:16054375 PMID:30408459 PMID:35762198 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 multiple interactions ISO Simvastatin results in increased cleavage of and results in increased activity of CASP12 protein CTD PMID:19253821 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity
decreases activity
increases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of CASP3 protein]; Simvastatin inhibits the reaction [APP protein alternative form results in decreased expression of CASP3 protein]; Simvastatin inhibits the reaction [APP protein alternative form results in increased activity of CASP3 protein]; Simvastatin inhibits the reaction [Coal Ash results in increased expression of CASP3 protein modified form]; Simvastatin inhibits the reaction [Homocysteine results in increased activity of CASP3 protein]; Simvastatin results in increased cleavage of and results in increased activity of CASP3 protein
Simvastatin results in increased cleavage of CASP3 protein
Simvastatin results in decreased activity of CASP3 protein
Simvastatin results in increased expression of CASP3 mRNA; Simvastatin results in increased expression of CASP3 protein
carvacrol inhibits the reaction [Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]]; PD 150606 inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein]; Simvastatin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of CASP3 mRNA]; Simvastatin promotes the reaction [Poloxamer results in increased expression of CASP3 protein]; Simvastatin results in decreased expression of and results in decreased activity of CASP3 protein; Simvastatin results in increased cleavage of and results in increased activity of CASP3 protein; Verapamil inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]
[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein; [Lipopolysaccharides co-treated with Simvastatin] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein] 		CTD PMID:11868908 PMID:12557325 PMID:12962723 PMID:14527821 PMID:15200425 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp6 caspase 6 multiple interactions ISO Simvastatin results in increased cleavage of and results in increased activity of CASP6 protein CTD PMID:19253821 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity 		ISO Mevalonic Acid inhibits the reaction [Simvastatin results in increased activity of CASP7 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of CASP7 protein]; Simvastatin results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:19253821 PMID:20045437 PMID:20427495 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases activity
multiple interactions
increases cleavage 		ISO Simvastatin results in increased activity of CASP8 protein
Simvastatin results in increased cleavage of and results in increased activity of CASP8 protein
Simvastatin results in increased cleavage of CASP8 protein
Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP8 protein] 		CTD PMID:12962723 PMID:15705602 PMID:20464445 PMID:20883752 PMID:21910007 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
decreases activity
increases cleavage 		ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in decreased activity of CASP9 protein]; DIABLO protein promotes the reaction [Simvastatin results in increased activity of CASP9 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of CASP9 protein]; Simvastatin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:12438947 PMID:12962723 PMID:15705602 PMID:16470222 PMID:19253821 More... Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases expression
multiple interactions
increases activity 		ISO
EXP 		Simvastatin results in decreased expression of CAT mRNA
carvacrol promotes the reaction [Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein]]; Simvastatin inhibits the reaction [Diazepam results in decreased activity of CAT protein]; Simvastatin inhibits the reaction [Poloxamer results in decreased activity of CAT protein]
Simvastatin results in increased activity of CAT protein 		CTD PMID:17479860 PMID:20883752 PMID:27111380 PMID:29071762 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 multiple interactions
decreases expression 		ISO
EXP 		Simvastatin inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]
Simvastatin inhibits the reaction [[Semaxinib co-treated with Oxygen deficiency] results in decreased expression of CAV1 protein]
Simvastatin results in decreased expression of CAV1 protein
Simvastatin promotes the reaction [[APOA4 protein co-treated with CBS protein] affects the expression of CAV1 protein] 		CTD PMID:16698853 PMID:18224302 PMID:19816600 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cav2 caveolin 2 multiple interactions EXP Simvastatin inhibits the reaction [[Semaxinib co-treated with Oxygen deficiency] results in decreased expression of CAV2 protein] CTD PMID:16698853 NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425 		JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO Simvastatin inhibits the reaction [[APOA4 protein co-treated with CBS protein] affects the abundance of Nitrogen Compounds]; Simvastatin promotes the reaction [[APOA4 protein co-treated with CBS protein] affects the expression of CAV1 protein] CTD PMID:18224302 NCBI chr20:9,709,394...9,733,925
Ensembl chr20:9,709,395...9,734,066 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression
affects expression
decreases response to substance 		ISO
EXP 		[Simvastatin co-treated with Ramipril] results in decreased expression of CCL2 protein; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL2 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [TNF results in increased secretion of CCL2 protein]; Simvastatin results in decreased expression of and results in decreased secretion of CCL2 protein
Simvastatin affects the expression of CCL2 mRNA
Simvastatin results in decreased expression of CCL2 mRNA; Simvastatin results in decreased expression of CCL2 protein
Simvastatin results in decreased susceptibility to CCL2 protein 		CTD PMID:12117737 PMID:12818400 PMID:15184351 PMID:15781755 PMID:15824212 More... NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression EXP Simvastatin results in decreased expression of CCL20 mRNA CTD PMID:22305382 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
decreases expression 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL3 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL3 mRNA]
Simvastatin results in decreased expression of CCL3 mRNA 		CTD PMID:16321392 PMID:16414398 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCL4 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL4 mRNA]; Simvastatin inhibits the reaction [TNF results in increased secretion of CCL4 mRNA] CTD PMID:16321392 NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
decreases expression 		ISO
EXP 		Simvastatin results in increased expression of CCL5 mRNA
Simvastatin results in decreased expression of CCL5 protein
Simvastatin results in decreased expression of CCL5 mRNA 		CTD PMID:17112859 PMID:17183729 PMID:17449418 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [CCN1 results in increased expression of IL1B]; Simvastatin inhibits the reaction [CCN1 results in increased expression of OSM]; Simvastatin inhibits the reaction [CCN1 results in increased expression of TNF]; Simvastatin inhibits the reaction [OSM results in increased expression of CCN1 mRNA]
Simvastatin results in decreased expression of CCN1 mRNA 		CTD PMID:17428261 PMID:20191585 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
decreases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]]; Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 protein]
Simvastatin results in decreased expression of CCN2 mRNA; Simvastatin results in decreased expression of CCN2 protein
Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]
Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] 		CTD PMID:15200425 PMID:15298857 PMID:15677772 PMID:19080365 PMID:19099753 More... NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of CCNA2 mRNA
Simvastatin results in decreased expression of CCNA2 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CCNA2 protein] 		CTD PMID:17428261 PMID:26577051 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]
Simvastatin results in decreased expression of CCND1 mRNA; Simvastatin results in decreased expression of CCND1 protein 		CTD PMID:17277159 PMID:17428261 PMID:20878096 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne1 cyclin E1 multiple interactions
decreases expression 		EXP geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CCNE1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CCNE1 protein] CTD PMID:26577051 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 multiple interactions
decreases expression 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR1 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR1 mRNA]
Simvastatin results in decreased expression of CCR1 mRNA 		CTD PMID:16321392 PMID:16414398 NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases expression 		ISO
EXP 		[2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [Simvastatin results in decreased expression of CCR2 mRNA]; [2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [Simvastatin results in decreased expression of CCR2 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR2 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR2 mRNA]
Simvastatin results in decreased expression of CCR2 mRNA; Simvastatin results in decreased expression of CCR2 protein 		CTD PMID:15781755 PMID:16321392 PMID:16414398 PMID:16781696 PMID:17449418 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr4 C-C motif chemokine receptor 4 multiple interactions ISO Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCR4 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR4 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of CCR4 mRNA] CTD PMID:16321392 NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions
decreases expression 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR5 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR5 mRNA]
Simvastatin results in decreased expression of CCR5 protein
Simvastatin results in decreased expression of CCR5 mRNA 		CTD PMID:16321392 PMID:17112859 PMID:17449418 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd14 CD14 molecule decreases expression EXP Simvastatin results in decreased expression of CD14 mRNA CTD PMID:16414398 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression EXP Simvastatin results in decreased expression of CD151 mRNA CTD PMID:16414398 NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784 		JBrowse link
G Cd24 CD24 molecule increases expression ISO Simvastatin results in increased expression of CD24 mRNA CTD PMID:18192897 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785 		JBrowse link
G Cd27 CD27 molecule decreases expression ISO Simvastatin results in decreased expression of CD27 mRNA CTD PMID:18453621 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823 		JBrowse link
G Cd2ap CD2-associated protein increases expression ISO Simvastatin results in increased expression of CD2AP mRNA CTD PMID:16710349 NCBI chr 9:25,580,071...25,679,968
Ensembl chr 9:25,583,975...25,679,968 		JBrowse link
G Cd40 CD40 molecule decreases expression
multiple interactions 		ISO Simvastatin results in decreased expression of CD40 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]]; Simvastatin inhibits the reaction [IFNG promotes the reaction [STAT1 binds to CD40 promoter]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]; Simvastatin promotes the reaction [IFNG promotes the reaction [RELA binds to CD40 promoter]] 		CTD PMID:16387846 PMID:17169357 PMID:17507688 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd40lg CD40 ligand decreases expression
multiple interactions
increases expression 		ISO Simvastatin results in decreased expression of CD40LG protein; Simvastatin results in decreased expression of CD40LG protein modified form
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CD40LG results in increased expression of VCAM1 mRNA]]; Simvastatin inhibits the reaction [CD40LG results in increased expression of VCAM1 mRNA]
Simvastatin results in increased expression of CD40LG protein 		CTD PMID:17169357 PMID:18269829 PMID:21330348 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd44 CD44 molecule multiple interactions
decreases expression 		ISO Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CD44 protein]; Simvastatin promotes the reaction [TP53 protein binds to CD44 promoter]
Simvastatin results in decreased expression of CD44 mRNA; Simvastatin results in decreased expression of CD44 protein 		CTD PMID:21199873 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd80 Cd80 molecule decreases expression EXP Simvastatin results in decreased expression of CD80 mRNA CTD PMID:22305382 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd83 CD83 molecule decreases expression ISO Simvastatin results in decreased expression of CD83 protein CTD PMID:16387846 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Cd86 CD86 molecule decreases expression ISO Simvastatin results in decreased expression of CD86 protein CTD PMID:16387846 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cdc25b cell division cycle 25B affects expression ISO Simvastatin affects the expression of CDC25B mRNA; Simvastatin affects the expression of CDC25B protein CTD PMID:19110722 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492 		JBrowse link
G Cdc42 cell division cycle 42 decreases activity ISO Simvastatin results in decreased activity of CDC42 protein CTD PMID:17169357 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Simvastatin results in decreased expression of CDC45 mRNA CTD PMID:17428261 NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Simvastatin results in decreased expression of CDC6 mRNA CTD PMID:17428261 NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241 		JBrowse link
G Cdh5 cadherin 5 increases expression EXP Simvastatin results in increased expression of CDH5 mRNA; Simvastatin results in increased expression of CDH5 protein CTD PMID:19109527 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of CDK1 mRNA; Simvastatin results in decreased expression of CDK1 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CDK1 protein] 		CTD PMID:17428261 PMID:20878096 PMID:26577051 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression
decreases activity 		ISO
EXP 		[Simvastatin results in decreased degradation of CDKN1A protein] which results in decreased activity of CDK2 protein; [Simvastatin results in decreased degradation of CDKN1B protein] which results in decreased activity of CDK2 protein
Simvastatin results in decreased expression of CDK2 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of CDK2 protein]
Simvastatin results in decreased activity of CDK2 protein 		CTD PMID:10412745 PMID:17928568 PMID:18804536 PMID:20878096 PMID:26577051 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression
decreases activity 		ISO
EXP 		Simvastatin results in decreased expression of CDK4 protein
Simvastatin results in decreased activity of CDK4 protein 		CTD PMID:18804536 PMID:20878096 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression ISO Simvastatin results in increased expression of CDK5 CTD PMID:19461118 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO
EXP 		[Simvastatin results in decreased degradation of CDKN1A protein] which results in decreased activity of CDK2 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of CDKN1A protein]; Simvastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein]
Simvastatin results in increased expression of CDKN1A mRNA; Simvastatin results in increased expression of CDKN1A protein 		CTD PMID:15625077 PMID:17428261 PMID:17928568 PMID:18337644 PMID:18625202 More... NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression 		ISO
EXP 		[Simvastatin results in decreased degradation of CDKN1B protein] which results in decreased activity of CDK2 protein
Simvastatin results in increased expression of CDKN1B mRNA; Simvastatin results in increased expression of CDKN1B protein 		CTD PMID:12963647 PMID:17428261 PMID:17928568 PMID:18337644 PMID:18804536 More... NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Simvastatin results in increased expression of CDKN1C mRNA CTD PMID:17428261 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression EXP Simvastatin results in increased expression of CDKN2A protein CTD PMID:18804536 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D increases expression ISO Simvastatin results in increased expression of CDKN2D mRNA; Simvastatin results in increased expression of CDKN2D protein CTD PMID:20878096 NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 decreases expression ISO Simvastatin results in decreased expression of CDT1 mRNA CTD PMID:17428261 NCBI chr19:67,529,249...67,534,195
Ensembl chr19:67,529,201...67,534,194 		JBrowse link
G Cebpz CCAAT/enhancer binding protein zeta multiple interactions ISO Simvastatin inhibits the reaction [CEBPZ binds to COL1A1 promoter] CTD PMID:16575855 NCBI chr 6:21,872,071...21,889,755
Ensembl chr 6:21,872,025...21,889,749 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions EXP
ISO 		Simvastatin affects the reaction [Dietary Fats affects the expression of CES1 mRNA]; Simvastatin affects the reaction [Dietary Fats affects the expression of CES1 protein]
Simvastatin inhibits the reaction [CES1 protein results in increased hydrolysis of remdesivir] 		CTD PMID:33383043 PMID:34774545 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression
decreases expression 		ISO Simvastatin inhibits the reaction [TNF protein results in increased expression of CFLAR protein]
Simvastatin results in increased expression of CFLAR mRNA; Simvastatin results in increased expression of CFLAR protein
Simvastatin results in decreased expression of CFLAR protein; Simvastatin results in decreased expression of CFLAR protein alternative form 		CTD PMID:17277159 PMID:18521906 PMID:19262002 PMID:21910007 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CFTR mRNA]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CFTR protein] CTD PMID:33774062 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Chat choline O-acetyltransferase multiple interactions ISO Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the activity of CHAT protein]; Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the expression of CHAT mRNA] CTD PMID:16828882 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 multiple interactions ISO Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the expression of CHRM5 mRNA] CTD PMID:16828882 NCBI chr 3:119,739,229...119,791,630
Ensembl chr 3:119,735,975...119,792,166 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases expression
increases phosphorylation 		ISO artemisinin inhibits the reaction [Simvastatin results in increased phosphorylation of CHUK protein]; parthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of CHUK protein]; Simvastatin promotes the reaction [Doxorubicin results in increased phosphorylation of CHUK protein]
Simvastatin results in increased expression of CHUK mRNA 		CTD PMID:18463201 PMID:19262002 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator multiple interactions ISO Simvastatin inhibits the reaction [IFNG results in increased expression of CIITA protein] CTD PMID:11219190 NCBI chr10:5,646,854...5,694,393
Ensembl chr10:5,647,085...5,694,342 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions
increases secretion
decreases expression 		ISO
EXP 		[Clarithromycin co-treated with Simvastatin] results in increased expression of CKM protein
Simvastatin results in increased secretion of CKM protein
carvacrol inhibits the reaction [Simvastatin results in increased secretion of CKM protein]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of CKM protein]
Simvastatin results in decreased expression of CKM protein 		CTD PMID:8611662 PMID:19252767 PMID:29071762 PMID:35762198 NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions
decreases expression 		EXP Simvastatin inhibits the reaction [EDN1 protein results in increased expression of CLCN3 protein]
Simvastatin results in decreased expression of CLCN3 protein 		CTD PMID:20644009 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Cldn18 claudin 18 multiple interactions EXP Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CLDN18 mRNA]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of CLDN18 protein] CTD PMID:33774062 NCBI chr 8:109,125,819...109,145,110
Ensembl chr 8:109,126,949...109,152,701 		JBrowse link
G Cldn4 claudin 4 multiple interactions EXP Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CLDN4 mRNA]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CLDN4 protein] CTD PMID:33774062 NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Simvastatin results in increased expression of COL11A1 mRNA CTD PMID:16274305 NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression ISO Simvastatin results in increased expression of COL12A1 mRNA CTD PMID:16274305 NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711 		JBrowse link
G Col13a1 collagen type XIII alpha 1 chain decreases response to substance ISO COL13A1 SNP results in decreased susceptibility to Simvastatin CTD PMID:21483694 NCBI chr20:30,326,744...30,466,800
Ensembl chr20:30,326,744...30,466,800 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression 		ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]; Simvastatin inhibits the reaction [CEBPZ binds to COL1A1 promoter]; Simvastatin inhibits the reaction [SP1 binds to COL1A1 promoter]
Simvastatin results in increased expression of COL1A1 mRNA 		CTD PMID:10412775 PMID:14973129 PMID:16274305 PMID:16575855 PMID:17252541 More... NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions
increases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of COL2A1 mRNA]; NOG inhibits the reaction [Simvastatin results in increased expression of COL2A1 mRNA] CTD PMID:18628692 PMID:19912653 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
decreases expression 		ISO
EXP 		Simvastatin results in increased expression of COL3A1 mRNA
Simvastatin results in decreased expression of COL3A1 mRNA 		CTD PMID:10412775 PMID:16274305 PMID:16414398 PMID:17183729 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO Simvastatin results in decreased expression of COL4A1 mRNA CTD PMID:10412775 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Simvastatin results in increased expression of COL5A1 mRNA CTD PMID:16274305 NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Simvastatin results in increased expression of COL6A2 mRNA CTD PMID:16274305 NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression ISO Simvastatin results in increased expression of COL7A1 mRNA CTD PMID:17428261 NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439 		JBrowse link
G Coro1a coronin 1A decreases expression EXP Simvastatin results in decreased expression of CORO1A protein CTD PMID:20217863 NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Simvastatin inhibits the reaction [OSM results in increased phosphorylation of CREB1 protein] CTD PMID:20191585 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crp C-reactive protein decreases expression
multiple interactions 		ISO Simvastatin results in decreased expression of CRP protein
[Ezetimibe co-treated with Simvastatin] results in decreased expression of CRP protein; [Simvastatin co-treated with Ezetimibe] promotes the reaction [Niacin results in decreased expression of CRP protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]]; Simvastatin inhibits the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in increased expression of CRP protein]; Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]; Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]; Simvastatin inhibits the reaction [ethinyl estradiol-desogestrel combination results in increased expression of CRP protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of CRP protein] 		CTD PMID:15184351 PMID:15824212 PMID:17105841 PMID:18023360 PMID:18420099 More... NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cs citrate synthase multiple interactions
increases activity 		EXP [Simvastatin co-treated with Lipopolysaccharides] results in increased activity of CS protein
Simvastatin results in increased activity of CS protein 		CTD PMID:25674200 NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression ISO Simvastatin results in increased expression of CSPG4 mRNA CTD PMID:19262002 NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:66,160,942...66,200,806 		JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of AGT mRNA]; Simvastatin inhibits the reaction [CTF1 results in increased expression of FOS mRNA]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein modified form]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]; Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT1 protein]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein modified form]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]; Simvastatin inhibits the reaction [CTF1 results in increased phosphorylation of JAK2 protein]; Simvastatin inhibits the reaction [CTF1 results in increased phosphorylation of STAT3 protein] CTD PMID:16534557 PMID:18400235 PMID:19100119 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 decreases expression ISO Simvastatin results in decreased expression of CTLA4 mRNA CTD PMID:18453621 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973 		JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO Simvastatin results in decreased expression of CTNNAL1 mRNA CTD PMID:17428261 NCBI chr 5:76,309,546...76,375,869
Ensembl chr 5:76,309,546...76,364,637 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression 		ISO
EXP 		CTNNB1 mutant form inhibits the reaction [Simvastatin results in increased expression of BGLAP protein]; CTNNB1 mutant form inhibits the reaction [Simvastatin results in increased expression of SP7 protein]
Simvastatin results in increased expression of CTNNB1 protein
Simvastatin inhibits the reaction [Glucose results in decreased expression of CTNNB1 protein] 		CTD PMID:18004065 PMID:22058016 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsl cathepsin L increases expression EXP Simvastatin results in increased expression of CTSL mRNA CTD PMID:19001041 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Ctss cathepsin S multiple interactions ISO Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of CTSS mRNA]; Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of CTSS protein] CTD PMID:20835264 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cttn cortactin affects localization
multiple interactions 		ISO Simvastatin affects the localization of CTTN protein
Simvastatin affects the reaction [F2 affects the localization of CTTN protein] 		CTD PMID:14630613 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO Simvastatin results in decreased expression of CX3CR1 mRNA CTD PMID:18359719 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
decreases expression 		ISO
EXP 		Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CXCL10 mRNA]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CXCL10 protein]
Simvastatin results in decreased expression of CXCL10 mRNA; Simvastatin results in decreased expression of CXCL10 protein 		CTD PMID:15187114 PMID:16414398 PMID:17449418 PMID:22305382 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression EXP Simvastatin results in increased expression of CXCL12 CTD PMID:19591934 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl16 C-X-C motif chemokine ligand 16 decreases expression EXP Simvastatin results in decreased expression of CXCL16 mRNA CTD PMID:25055962 NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO Simvastatin results in decreased expression of CXCL2 mRNA; Simvastatin results in decreased expression of CXCL2 protein CTD PMID:21330348 PMID:21441352 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Simvastatin results in decreased expression of CXCL1 mRNA; Simvastatin results in decreased expression of CXCL1 protein CTD PMID:21330348 PMID:21441352 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression EXP Simvastatin results in decreased expression of CXCR2 mRNA CTD PMID:16414398 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression
increases expression 		EXP Simvastatin results in decreased expression of CXCR4 mRNA
Simvastatin results in increased expression of CXCR4 		CTD PMID:16414398 PMID:19591934 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Cyba cytochrome b-245 alpha chain affects response to substance ISO CYBA gene SNP affects the susceptibility to Simvastatin CTD PMID:15936011 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO Simvastatin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB protein] CTD PMID:30513525 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11A1 mRNA; [Simvastatin co-treated with resveratrol] results in decreased expression of CYP11A1 mRNA CTD PMID:24524197 PMID:25055962 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B1 mRNA CTD PMID:25055962 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B2 mRNA CTD PMID:25055962 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions 		EXP Simvastatin results in decreased expression of CYP17A1 mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA; farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA]; resveratrol promotes the reaction [Simvastatin results in decreased expression of CYP17A1 mRNA]; Simvastatin promotes the reaction [resveratrol results in decreased expression of CYP17A1 mRNA] 		CTD PMID:21918126 PMID:24524197 PMID:25055962 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Simvastatin results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Simvastatin results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions EXP Simvastatin promotes the reaction [Dietary Fats results in increased expression of CYP27A1 mRNA] CTD PMID:33383043 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Simvastatin results in increased expression of CYP2B6 mRNA CTD PMID:15802384 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Simvastatin results in decreased activity of CYP2C8 protein CTD PMID:15601807
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance ISO CYP2D6 polymorphism affects the susceptibility to Simvastatin CTD PMID:11753271 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression EXP Simvastatin results in decreased expression of CYP39A1 mRNA CTD PMID:25055962 NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects response to substance
increases metabolic processing
increases expression
affects metabolic processing
decreases expression
decreases activity 		EXP
ISO 		Berberine promotes the reaction [Simvastatin results in decreased activity of CYP3A4 protein]; Berberine promotes the reaction [Simvastatin results in decreased expression of CYP3A4 protein]; Simvastatin promotes the reaction [Berberine results in decreased activity of CYP3A4 protein]
CYP3A4 polymorphism affects the susceptibility to Simvastatin
[Simvastatin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Simvastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; ABCB1 alternative form affects the reaction [CYP3A4 polymorphism affects the susceptibility to Simvastatin]; telaprevir inhibits the reaction [CYP3A4 protein results in increased metabolism of Simvastatin]
Simvastatin results in increased expression of CYP3A4 mRNA
CYP3A4 protein affects the metabolism of Simvastatin
Simvastatin results in decreased expression of CYP3A4 mRNA; Simvastatin results in decreased expression of CYP3A4 protein 		CTD PMID:12505310 PMID:15650881 PMID:16011971 PMID:17041008 PMID:19802823 More... NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects response to substance ISO CYP3A5 polymorphism affects the susceptibility to Simvastatin CTD PMID:17192506 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 decreases expression EXP Simvastatin results in decreased expression of CYP46A1 mRNA CTD PMID:25055962 NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971 		JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Simvastatin results in increased expression of CYP51 mRNA CTD PMID:25055962 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions EXP
ISO 		Simvastatin promotes the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]; Simvastatin promotes the reaction [Dietary Fats results in increased expression of CYP7A1 protein]
Simvastatin inhibits the reaction [osteum results in decreased expression of CYP7A1 mRNA] 		CTD PMID:33383043 PMID:33596472 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO Simvastatin results in decreased expression of DBF4 mRNA CTD PMID:17428261 NCBI chr 4:26,631,491...26,656,080
Ensembl chr 4:26,631,514...26,656,562 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of DBP mRNA] CTD PMID:16373842 NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205 		JBrowse link
G Dcx doublecortin increases expression EXP Simvastatin results in increased expression of DCX CTD PMID:18544044 NCBI chr  X:112,227,455...112,370,291
Ensembl chr  X:112,227,455...112,304,161 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression EXP Simvastatin results in decreased expression of DDAH1 mRNA CTD PMID:16414398 NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression
increases activity 		EXP Simvastatin results in increased expression of DGAT1 mRNA
Simvastatin results in increased activity of DGAT1 protein 		CTD PMID:12056585 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO
EXP 		Simvastatin results in increased expression of DHCR24
Simvastatin results in increased expression of DHCR24 mRNA
Simvastatin results in increased expression of DHCR24 mRNA; Simvastatin results in increased expression of DHCR24 protein 		CTD PMID:21987590 PMID:25055962 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase affects response to substance
affects expression
multiple interactions 		ISO
EXP 		DHCR7 mutant form affects the susceptibility to Simvastatin
Simvastatin affects the expression of DHCR7 mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of DHCR7 mRNA
Simvastatin inhibits the reaction [DHCR7 mutant form results in increased abundance of 7-dehydrocholesterol]
Hydroxychloroquine affects the reaction [Simvastatin affects the expression of DHCR7 mRNA]; Simvastatin promotes the reaction [DHCR7 results in increased chemical synthesis of Cholesterol] 		CTD PMID:15896653 PMID:16446309 PMID:19365639 PMID:25055962 PMID:28975700 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects localization
multiple interactions 		ISO Simvastatin affects the localization of DIABLO protein
DIABLO protein promotes the reaction [Simvastatin results in increased activity of CASP9 protein] 		CTD PMID:20045437 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO DKK1 inhibits the reaction [Simvastatin results in increased expression of BGLAP mRNA]; DKK1 inhibits the reaction [Simvastatin results in increased expression of RUNX2 mRNA]; DKK1 inhibits the reaction [Simvastatin results in increased expression of SP7 mRNA] CTD PMID:22058016 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 increases expression EXP Simvastatin results in increased expression of DLL4 mRNA CTD PMID:19109527 NCBI chr 3:126,770,945...126,780,769
Ensembl chr 3:126,770,794...126,780,763 		JBrowse link
G Dnm1l dynamin 1-like affects localization
increases expression 		ISO Simvastatin affects the localization of DNM1L protein
Simvastatin results in increased expression of DNM1L protein 		CTD PMID:20045437 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
increases expression 		EXP SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]]; Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]; Simvastatin promotes the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]
Simvastatin results in increased expression of DRD1 mRNA; Simvastatin results in increased expression of DRD1 protein 		CTD PMID:15711596 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Drd2 dopamine receptor D2 increases expression EXP Simvastatin results in increased expression of DRD2 mRNA; Simvastatin results in increased expression of DRD2 protein CTD PMID:15711596 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Dspp dentin sialophosphoprotein increases expression ISO Simvastatin results in increased expression of DSPP mRNA CTD PMID:19249597 NCBI chr14:5,870,232...5,876,339
Ensembl chr14:5,870,232...5,876,339 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Simvastatin results in decreased expression of DUSP1 mRNA; Simvastatin results in decreased expression of DUSP1 protein CTD PMID:21080865 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Simvastatin results in decreased expression of E2F1 mRNA CTD PMID:17428261 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G Eaf2 ELL associated factor 2 decreases response to substance ISO EAF2 SNP results in decreased susceptibility to Simvastatin CTD PMID:21483694 NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993 		JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased secretion of EDN1 protein
Simvastatin results in decreased expression of EDN1 mRNA
Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of EDN1 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of EDN1 protein]; Simvastatin results in increased expression of and results in increased secretion of EDN1 protein
Simvastatin results in decreased expression of EDN1 mRNA; Simvastatin results in decreased expression of EDN1 protein
Simvastatin inhibits the reaction [EDN1 protein results in increased expression of CLCN3 protein]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of EDN1 mRNA] 		CTD PMID:16375908 PMID:18390205 PMID:19099753 PMID:20369390 PMID:20644009 More... NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of EDNRA mRNA]; Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of EDNRA protein]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of EDNRA mRNA] CTD PMID:19505368 PMID:22022327 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]]; Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egr1 early growth response 1 decreases expression ISO Simvastatin results in decreased expression of EGR1 protein CTD PMID:12818400 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions 		ISO Simvastatin results in decreased phosphorylation of EIF4EBP1 protein
IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of EIF4EBP1 protein] 		CTD PMID:22144680 PMID:27734117 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Eno1 enolase 1 decreases expression EXP Simvastatin results in decreased expression of ENO1 protein CTD PMID:20217863 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions ISO Simvastatin inhibits the reaction [F2 protein results in decreased expression of ENTPD1 protein] CTD PMID:12067895 NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:249,374,836...249,502,317 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA CTD PMID:28263720 NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425 		JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA CTD PMID:28263720 NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966 		JBrowse link
G Epo erythropoietin multiple interactions EXP Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] CTD PMID:20821229 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G Epor erythropoietin receptor multiple interactions EXP Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA] CTD PMID:20821229 NCBI chr 8:28,765,738...28,770,371
Ensembl chr 8:28,765,746...28,770,322 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions
decreases activity 		ISO Cycloheximide inhibits the reaction [Simvastatin results in decreased activity of F2 protein]; Simvastatin affects the reaction [F2 affects the localization of CTTN protein]; Simvastatin inhibits the reaction [F2 protein results in decreased expression of ENTPD1 protein] CTD PMID:12067895 PMID:14630613 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases activity
decreases expression
affects response to substance
increases expression 		ISO geranylgeraniol inhibits the reaction [Simvastatin results in decreased expression of F3]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of F3 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of F3]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein]
Simvastatin results in decreased activity of F3 protein
F3 polymorphism affects the susceptibility to Simvastatin
Simvastatin results in increased expression of F3 mRNA; Simvastatin results in increased expression of F3 protein
Simvastatin results in decreased expression of F3; Simvastatin results in decreased expression of F3 mRNA; Simvastatin results in decreased expression of F3 protein 		CTD PMID:9081680 PMID:10830219 PMID:12753293 PMID:12818400 PMID:15824212 More... NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fasn fatty acid synthase increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of FASN mRNA
Simvastatin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in increased expression of FASN protein] 		CTD PMID:11728391 PMID:12056585 PMID:39536891 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fbxo32 F-box protein 32 increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of FBXO32 mRNA; Simvastatin results in increased expression of FBXO32 protein
FST protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 mRNA]; FST protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 mRNA] 		CTD PMID:19001041 PMID:25300705 PMID:27734117 PMID:33034787 NCBI chr 7:91,620,925...91,654,491
Ensembl chr 7:91,620,925...91,654,491 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression
multiple interactions
increases activity 		EXP
ISO 		Simvastatin results in increased expression of FDFT1 protein
Simvastatin results in increased expression of FDFT1 mRNA
resveratrol inhibits the reaction [Simvastatin results in increased expression of FDFT1 mRNA]
Simvastatin results in increased activity of FDFT1 protein 		CTD PMID:8517861 PMID:12518039 PMID:23386644 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression
multiple interactions 		ISO Simvastatin results in increased expression of FDPS mRNA
resveratrol inhibits the reaction [Simvastatin results in increased expression of FDPS mRNA] 		CTD PMID:23386644 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions EXP Simvastatin inhibits the reaction [Dietary Fats results in increased expression of FGF19 mRNA] CTD PMID:33383043 NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Simvastatin results in increased expression of FGF2 CTD PMID:20381859 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A decreases expression EXP Simvastatin results in decreased expression of FKBP1A mRNA CTD PMID:16414398 NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 increases expression ISO Simvastatin results in increased expression of FKBP4 mRNA CTD PMID:19262002 NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918 		JBrowse link
G Flot1 flotillin 1 decreases expression ISO Simvastatin results in decreased expression of FLOT1 protein CTD PMID:12628479 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression 		EXP Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]
Simvastatin results in increased expression of FLT1 mRNA 		CTD PMID:19109527 PMID:20821229 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression 		ISO
EXP 		Simvastatin results in decreased expression of FN1 mRNA
Simvastatin results in increased expression of FN1 mRNA 		CTD PMID:10412775 PMID:15855201 PMID:16274305 PMID:16414398 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
decreases localization 		ISO
EXP 		farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of FOS mRNA]
Simvastatin inhibits the reaction [CTF1 results in increased expression of FOS mRNA]
FOS inhibits the reaction [Simvastatin results in increased expression of IL12B mRNA]; Simvastatin affects the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [JUN protein binds to JUNB protein binds to FOS protein binds to FOSB protein binds to FOSL2 protein]]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of FOS protein]
Simvastatin results in decreased localization of FOS protein 		CTD PMID:12753293 PMID:12963647 PMID:15187114 PMID:16005304 PMID:19100119 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Simvastatin affects the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [JUN protein binds to JUNB protein binds to FOS protein binds to FOSB protein binds to FOSL2 protein]] CTD PMID:15187114 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Simvastatin results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO Simvastatin affects the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [JUN protein binds to JUNB protein binds to FOS protein binds to FOSB protein binds to FOSL2 protein]] CTD PMID:15187114 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406 		JBrowse link
G Foxo1 forkhead box O1 affects localization
decreases phosphorylation
multiple interactions
decreases localization
increases phosphorylation 		EXP
ISO 		Simvastatin affects the localization of FOXO1 protein
Simvastatin results in decreased phosphorylation of FOXO1 protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of FOXO1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased phosphorylation of and affects the localization of FOXO1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of and affects the localization of FOXO1 protein]
Simvastatin results in decreased localization of FOXO1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in decreased localization of FOXO1 protein]
Simvastatin results in increased phosphorylation of FOXO1 protein 		CTD PMID:12438947 PMID:18826357 PMID:19001041 PMID:33034787 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions
affects localization
decreases phosphorylation
decreases expression
increases phosphorylation 		ISO
EXP 		Acetylcysteine inhibits the reaction [Simvastatin results in increased phosphorylation of FOXO3 protein]; IGF1 protein inhibits the reaction [Simvastatin affects the localization of FOXO3 protein]
Simvastatin affects the localization of FOXO3A protein
Simvastatin results in decreased phosphorylation of FOXO3 protein
Simvastatin results in decreased expression of FOXO3 protein 		CTD PMID:19001041 PMID:20883752 PMID:25300705 PMID:27734117 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Foxp3 forkhead box P3 increases expression
decreases expression
affects methylation
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of FOXP3
Simvastatin results in decreased expression of FOXP3 mRNA
Simvastatin affects the methylation of FOXP3 promoter
IL2 affects the reaction [Simvastatin results in increased expression of FOXP3]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of FOXP3] 		CTD PMID:20408897 PMID:20491794 PMID:22305382 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Fst follistatin multiple interactions ISO FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of MTOR protein]; FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein]; FST protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 mRNA]; FST protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 protein]; FST protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 mRNA]; FST protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 protein]; FST protein inhibits the reaction [Simvastatin results in increased phosphorylation of SMAD2 protein]; FST protein inhibits the reaction [Simvastatin results in increased phosphorylation of SMAD3 protein] CTD PMID:33034787 NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491 		JBrowse link
G Fzd2 frizzled class receptor 2 increases expression EXP Simvastatin results in increased expression of FZD2 mRNA CTD PMID:19968183 NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Simvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA CTD PMID:24204015 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression EXP Simvastatin results in decreased expression of GAPDH mRNA CTD PMID:16414398 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377 		JBrowse link
G Gata6 GATA binding protein 6 increases expression EXP Simvastatin results in increased expression of GATA6 mRNA; Simvastatin results in increased expression of GATA6 protein CTD PMID:19842842 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322 		JBrowse link
G Gdi2 GDP dissociation inhibitor 2 decreases expression EXP Simvastatin results in decreased expression of GDI2 protein CTD PMID:20217863 NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147 		JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression EXP Simvastatin results in increased expression of GDNF CTD PMID:20851742 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA CTD PMID:28263720 NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO GJA1 protein affects the reaction [Simvastatin results in increased susceptibility to Etoposide]; Simvastatin affects the localization of and results in decreased phosphorylation of GJA1 protein CTD PMID:23978459 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression ISO Simvastatin results in increased expression of GJB2 mRNA CTD PMID:17428261 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877 		JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions ISO Simvastatin inhibits the reaction [Coal Ash results in increased expression of GLB1 protein] CTD PMID:26773838 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Simvastatin inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:39536891 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of GPX1 mRNA
Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] 		CTD PMID:20883752 PMID:28734741 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP Simvastatin results in increased expression of GPX2 mRNA CTD PMID:18787804 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of GSK3B
Simvastatin results in increased expression of GSK3B protein modified form
Simvastatin inhibits the reaction [Glucose results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of GSK3B protein] 		CTD PMID:18004065 PMID:18047562 PMID:19461118 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Simvastatin inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Simvastatin results in increased phosphorylation of H2AX protein CTD PMID:20499237 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 increases expression EXP Simvastatin results in increased expression of HES5 mRNA CTD PMID:19109527 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
decreases expression 		ISO
EXP 		Simvastatin results in increased expression of HIF1A protein
Simvastatin inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in increased expression of HIF1A protein]
Simvastatin results in decreased expression of HIF1A mRNA
HIF1A mutant form inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA] 		CTD PMID:18356691 PMID:21844074 PMID:39536891 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP
ISO 		Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholecalciferol] results in increased expression of HMGB1 mRNA]
[Simvastatin co-treated with Metformin] results in increased secretion of HMGB1 protein; necrostatin-1 inhibits the reaction [[Simvastatin co-treated with Metformin] results in increased secretion of HMGB1 protein] 		CTD PMID:20519084 PMID:25412314 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases response to substance
decreases activity
increases expression
increases activity
multiple interactions
affects response to substance 		ISO
EXP 		HMGCR exon alternative form results in decreased susceptibility to Simvastatin
Simvastatin results in decreased activity of HMGCR protein
Simvastatin results in increased expression of HMGCR mRNA; Simvastatin results in increased expression of HMGCR protein
Simvastatin results in increased activity of HMGCR protein
Mevalonic Acid inhibits the reaction [Simvastatin results in increased activity of HMGCR protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of HMGCR mRNA]; resveratrol inhibits the reaction [Simvastatin results in increased expression of HMGCR mRNA]; resveratrol inhibits the reaction [Simvastatin results in increased expression of HMGCR protein]; resveratrol promotes the reaction [Simvastatin results in decreased activity of HMGCR protein]; Simvastatin results in increased expression of and results in decreased activity of HMGCR protein; Simvastatin results in increased expression of and results in increased activity of HMGCR protein
Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA]
[HMGCR intron polymorphism affects the expression of HMGCR exon alternative form] which results in decreased susceptibility to Simvastatin; [MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to Simvastatin; [Simvastatin co-treated with Ezetimibe] results in increased expression of HMGCR mRNA; HMGCR polymorphism promotes the reaction [[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB]; MVK gene mutant form promotes the reaction [Simvastatin results in decreased activity of HMGCR protein]; Resveratrol inhibits the reaction [Simvastatin results in increased expression of HMGCR mRNA]; Resveratrol inhibits the reaction [Simvastatin results in increased expression of HMGCR protein]; Resveratrol promotes the reaction [Simvastatin results in decreased activity of HMGCR protein]; Simvastatin affects the reaction [Hydroxychloroquine affects the expression of HMGCR mRNA]; Simvastatin inhibits the reaction [osteum results in increased expression of HMGCR mRNA]; Simvastatin results in increased expression of and results in increased activity of HMGCR protein
HMGCR intron polymorphism affects the susceptibility to Simvastatin; HMGCR polymorphism affects the susceptibility to Simvastatin 		CTD PMID:1627634 PMID:8517861 PMID:8593127 PMID:9512650 PMID:10357840 More... NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases response to substance
increases expression
increases activity
decreases expression
increases stability 		ISO
EXP 		[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which affects the localization of RELA protein; [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased abundance of Superoxides; [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased phosphorylation of NFKBIA protein; [Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein; Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 protein]; NFE2L2 mutant form inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]]; zinc protoporphyrin inhibits the reaction [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 protein]]
HMOX1 gene mutant form results in increased susceptibility to Simvastatin
Simvastatin results in increased expression of HMOX1 mRNA; Simvastatin results in increased expression of HMOX1 protein
Simvastatin results in increased activity of HMOX1 protein
Simvastatin results in decreased expression of HMOX1 mRNA
Simvastatin results in increased stability of HMOX1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin results in increased stability of HMOX1 mRNA]; MAPK1 promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [Simvastatin results in increased expression of HMOX1 mRNA]
[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which affects the localization of RELA protein; [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased abundance of Superoxides; [[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased phosphorylation of NFKBIA protein; [Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein; tin protoporphyrin IX inhibits the reaction [Simvastatin results in increased expression of HMOX1 protein] 		CTD PMID:16375908 PMID:16414398 PMID:16628357 PMID:17928392 PMID:18073186 More... NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnf1a HNF1 homeobox A increases expression ISO Simvastatin results in increased expression of HNF1A mRNA CTD PMID:22160096 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions
decreases activity 		ISO Farnesol inhibits the reaction [Simvastatin results in decreased farnesylation of and affects the localization of HRAS protein]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]]; MVK gene mutant form promotes the reaction [Simvastatin results in decreased farnesylation of and affects the localization of HRAS protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of HRAS protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of HRAS protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased prenylation of HRAS protein]; Simvastatin results in decreased prenylation of and results in decreased localization of HRAS protein
Simvastatin results in decreased activity of HRAS 		CTD PMID:11914545 PMID:12477733 PMID:18625914 PMID:19360310 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Simvastatin co-treated with resveratrol] results in decreased expression of HSD3B1 mRNA CTD PMID:24524197 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsf1 heat shock transcription factor 1 affects localization ISO Simvastatin affects the localization of HSF1 protein CTD PMID:16375908 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Simvastatin results in increased expression of HSP90AA1 protein CTD PMID:16375908 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO Simvastatin results in increased expression of HSPA4 protein CTD PMID:16375908 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Simvastatin results in increased expression of HSPA5 mRNA; Simvastatin results in increased expression of HSPA5 protein CTD PMID:18664198 PMID:19253821 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression EXP Simvastatin results in decreased expression of HSPA8 protein CTD PMID:20217863 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Htra2 HtrA serine peptidase 2 affects localization ISO Simvastatin affects the localization of HTRA2 protein CTD PMID:20045437 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:117,114,633...117,117,793 		JBrowse link
G Ibsp integrin-binding sialoprotein increases expression ISO Simvastatin results in increased expression of IBSP mRNA CTD PMID:20417880 NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression 		ISO
EXP 		farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; Simvastatin affects the expression of and affects the secretion of ICAM1 protein; Simvastatin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1]; Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]; Vitamin E inhibits the reaction [Simvastatin results in decreased expression of ICAM1 protein modified form]
Simvastatin results in decreased expression of ICAM1 mRNA; Simvastatin results in decreased expression of ICAM1 protein
Simvastatin results in decreased expression of ICAM1 mRNA; Simvastatin results in decreased expression of ICAM1 protein; Simvastatin results in decreased expression of ICAM1 protein modified form 		CTD PMID:10946302 PMID:12615677 PMID:14602771 PMID:15234187 PMID:16054375 More... NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Simvastatin results in increased expression of ID1 mRNA CTD PMID:19262002 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP Simvastatin results in increased expression of IDI1 mRNA CTD PMID:25055962 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 increases expression ISO Simvastatin results in increased expression of IDO1 CTD PMID:20491794 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ifng interferon gamma multiple interactions
increases secretion
increases expression 		ISO IFNG affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IFNG affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; IFNG affects the reaction [Simvastatin results in decreased secretion of IL17A protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL3 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCL4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR1 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CCR5 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 protein]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR1 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR2 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR4 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CCR5 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CIITA protein]; Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA protein]; Simvastatin inhibits the reaction [IFNG results in increased expression of PTGS2]; Simvastatin inhibits the reaction [IFNG results in increased expression of STAT1 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 protein]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 protein]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL2 protein]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL3 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased secretion of CCL4 mRNA]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]]; Simvastatin inhibits the reaction [IFNG promotes the reaction [STAT1 binds to CD40 promoter]]; Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of CD40 protein]; Simvastatin inhibits the reaction [IFNG results in increased expression of IRF1 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased phosphorylation of STAT1 protein]; Simvastatin promotes the reaction [IFNG promotes the reaction [RELA binds to CD40 promoter]]; Simvastatin promotes the reaction [IFNG results in increased expression of PTGS2]
Simvastatin results in increased secretion of IFNG protein
Simvastatin results in increased expression of IFNG mRNA 		CTD PMID:11219190 PMID:16321392 PMID:17507688 PMID:18453621 PMID:19589242 More... NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Simvastatin co-treated with NVP-AEW541] inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]; IGF1 protein inhibits the reaction [Simvastatin affects the localization of FOXO3 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of AKT1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of BAD protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of EIF4EBP1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased cleavage of CASP3 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased expression of FBXO32 mRNA]; IGF1 protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 mRNA]; Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]; Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IRS1 protein]; Simvastatin inhibits the reaction [IGF1 results in increased activity of AKT1 protein]; Simvastatin inhibits the reaction [IGF1 results in increased activity of MAPK1 protein]; Simvastatin inhibits the reaction [IGF1 results in increased activity of MAPK3 protein] CTD PMID:17327694 PMID:27734117 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
multiple interactions
increases expression 		ISO Simvastatin results in decreased expression of IGF1R; Simvastatin results in decreased expression of IGF1R mRNA; Simvastatin results in decreased expression of IGF1R protein
[Simvastatin co-treated with NVP-AEW541] inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]; Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]
Simvastatin results in increased expression of IGF1R protein alternative form 		CTD PMID:17158816 PMID:17327694 PMID:18489904 PMID:27734117 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO Simvastatin results in increased expression of IGFBP6 mRNA CTD PMID:17428261 NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
increases phosphorylation
decreases expression 		ISO artemisinin inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein]; parthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein]; Simvastatin promotes the reaction [Doxorubicin results in increased phosphorylation of IKBKB protein]
Simvastatin results in decreased expression of IKBKB mRNA 		CTD PMID:17277159 PMID:18463201 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of IL10
1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of IL10 protein]]; [Lipopolysaccharides co-treated with Simvastatin] results in increased expression of and results in increased secretion of IL10 protein; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of IL10 protein]
Simvastatin promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein]
Simvastatin results in increased expression of IL10 mRNA; Simvastatin results in increased expression of IL10 protein 		CTD PMID:15883752 PMID:20491794 PMID:21925249 PMID:25674200 PMID:33774062 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B multiple interactions
increases expression 		ISO FOS inhibits the reaction [Simvastatin results in increased expression of IL12B mRNA]; JUN promotes the reaction [Simvastatin results in increased expression of IL12B mRNA]; Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B mRNA]; Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL12B protein]; Simvastatin promotes the reaction [Pam(3)CSK(4) peptide results in increased expression of IL12B protein]; Simvastatin promotes the reaction [resiquimod results in increased expression of IL12B protein] CTD PMID:15187114 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13 interleukin 13 decreases expression ISO Simvastatin results in decreased expression of IL13 mRNA; Simvastatin results in decreased expression of IL13 protein CTD PMID:17169357 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il16 interleukin 16 multiple interactions ISO [Lipopolysaccharides co-treated with Simvastatin] results in increased expression of IL16 mRNA CTD PMID:15665042 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:147,027,097...147,127,023 		JBrowse link
G Il17a interleukin 17A multiple interactions
decreases secretion
decreases expression 		ISO IFNG affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IFNG affects the reaction [Simvastatin results in decreased secretion of IL17A protein]; IL27 affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IL27 affects the reaction [Simvastatin results in decreased secretion of IL17A protein]; IL4 affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IL4 affects the reaction [Simvastatin results in decreased secretion of IL17A protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of IL17A mRNA] CTD PMID:18453621 PMID:21856936 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il17f interleukin 17F decreases secretion ISO Simvastatin results in decreased secretion of IL17F protein CTD PMID:21856936 NCBI chr 9:30,686,532...30,697,918
Ensembl chr 9:30,686,538...30,697,918 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP
ISO 		Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]]; Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]
Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] 		CTD PMID:18660453 PMID:27377765 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]]; Simvastatin inhibits the reaction [IL1A results in decreased expression of NFKBIA protein modified form]; Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]; Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]; Simvastatin inhibits the reaction [IL1A results in increased expression of NOS2 mRNA]; Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]; Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased abundance of Nitric Oxide]] 		CTD PMID:15705589 PMID:15728660 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion
decreases expression 		EXP
ISO 		1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]]; Simvastatin affects the reaction [Doxorubicin results in increased expression of IL1B mRNA]; Simvastatin affects the reaction [Doxorubicin results in increased expression of IL1B protein]; Simvastatin inhibits the reaction [Acetic Acid results in increased expression of IL1B protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of IL1B mRNA]
Simvastatin results in decreased secretion of IL1B protein
Simvastatin results in decreased expression of IL1B mRNA; Simvastatin results in decreased expression of IL1B protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; Simvastatin affects the reaction [IL1B protein results in increased activity of MMP2 protein]; Simvastatin inhibits the reaction [CCN1 results in increased expression of IL1B]; Simvastatin inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP2 mRNA]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [TNF results in increased localization of IL1B protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]; Simvastatin promotes the reaction [IL1B protein results in increased expression of ICAM1 protein]; Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE mRNA]; Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]; Simvastatin promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] 		CTD PMID:10946302 PMID:12829860 PMID:15883752 PMID:16054375 PMID:17075836 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression EXP Simvastatin results in decreased expression of IL1R2 mRNA CTD PMID:16414398 NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 decreases expression EXP Simvastatin results in decreased expression of IL1RL1 mRNA CTD PMID:16414398 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO IL2 affects the reaction [Simvastatin results in increased expression of FOXP3] CTD PMID:20408897 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta increases expression ISO Simvastatin results in increased expression of IL20RB mRNA CTD PMID:17428261 NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363 		JBrowse link
G Il21 interleukin 21 decreases expression
decreases secretion 		ISO Simvastatin results in decreased expression of IL21 mRNA
Simvastatin results in decreased secretion of IL21 protein 		CTD PMID:18453621 PMID:21856936 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il22 interleukin 22 decreases secretion ISO Simvastatin results in decreased secretion of IL22 protein CTD PMID:21856936 NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201 		JBrowse link
G Il23a interleukin 23 subunit alpha decreases expression ISO
EXP 		Simvastatin results in decreased expression of IL23A mRNA CTD PMID:18453621 PMID:22305382 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il25 interleukin 25 decreases expression EXP Simvastatin results in decreased expression of IL25 mRNA CTD PMID:22305382 NCBI chr15:32,378,750...32,382,141
Ensembl chr15:32,378,750...32,382,141 		JBrowse link
G Il27 interleukin 27 increases expression
increases secretion
multiple interactions 		ISO Simvastatin results in increased expression of IL27 mRNA
Simvastatin results in increased secretion of IL27 protein
IL27 affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IL27 affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; IL27 affects the reaction [Simvastatin results in decreased secretion of IL17A protein] 		CTD PMID:18453621 NCBI chr 1:190,603,684...190,609,292
Ensembl chr 1:190,603,522...190,609,258 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha affects expression
decreases expression 		ISO Simvastatin affects the expression of IL2RA protein
Simvastatin results in decreased expression of IL2RA mRNA 		CTD PMID:16387846 PMID:18453621 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
increases secretion
increases expression 		ISO IL4 affects the reaction [Simvastatin results in decreased expression of IL17A mRNA]; IL4 affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; IL4 affects the reaction [Simvastatin results in decreased secretion of IL17A protein]
Simvastatin results in decreased expression of IL4 mRNA; Simvastatin results in decreased expression of IL4 protein
Simvastatin results in increased secretion of IL4 protein
Simvastatin results in increased expression of IL4 mRNA 		CTD PMID:17169357 PMID:18453621 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il4r interleukin 4 receptor decreases expression ISO
EXP 		Simvastatin results in decreased expression of IL4R mRNA
Simvastatin results in decreased expression of IL4RA mRNA 		CTD PMID:16414398 PMID:18453621 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il6 interleukin 6 multiple interactions
affects secretion
decreases secretion
decreases expression
increases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of IL6 mRNA]; Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA protein]; Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Simvastatin inhibits the reaction [TNF results in increased localization of IL6 protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Simvastatin results in decreased expression of and results in decreased secretion of IL6 protein
Simvastatin affects the secretion of IL6 protein
Simvastatin results in decreased secretion of IL6 protein
Simvastatin results in decreased expression of IL6 mRNA; Simvastatin results in decreased expression of IL6 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]
Simvastatin results in increased expression of IL6 mRNA
Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein] 		CTD PMID:12117737 PMID:15665042 PMID:15883752 PMID:16387846 PMID:16424782 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inha inhibin subunit alpha multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INHA mRNA CTD PMID:25055962 NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009 		JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Simvastatin results in decreased expression of INSIG2 mRNA CTD PMID:25055962 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Insl3 insulin-like 3 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INSL3 mRNA CTD PMID:25055962 NCBI chr16:18,432,668...18,434,539 JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Simvastatin inhibits the reaction [IFNG results in increased expression of IRF1 mRNA] CTD PMID:17507688 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Irf4 interferon regulatory factor 4 decreases expression
multiple interactions 		ISO Simvastatin results in decreased expression of IRF4 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of IRF4 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of IRF4 protein]; IRF4 protein inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; IRF4 protein inhibits the reaction [Simvastatin results in increased expression of MSTN protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of IRF4 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of IRF4 protein]
Simvastatin results in decreased expression of IRF4 mRNA; Simvastatin results in decreased expression of IRF4 protein 		CTD PMID:21856936 PMID:33034787 NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO Simvastatin inhibits the reaction [IGF1 protein results in increased phosphorylation of IRS1 protein] CTD PMID:27734117 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Itgal integrin subunit alpha L affects binding
decreases expression
multiple interactions 		ISO Simvastatin binds to [ITGAL protein binds to ITGB2 protein]
Simvastatin results in decreased expression of ITGAL mRNA
Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the activity of CHAT protein]; Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the expression of CHAT mRNA]; Simvastatin inhibits the reaction [ITGAL affects the susceptibility to and affects the expression of CHRM5 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of ITGAL] 		CTD PMID:12615677 PMID:15041742 PMID:16828882 NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225 		JBrowse link
G Itgam integrin subunit alpha M decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of ITGAM mRNA; Simvastatin results in decreased expression of ITGAM protein
Simvastatin results in decreased expression of [ITGAM protein binds to ITGB2 protein] 		CTD PMID:16414398 PMID:21330348 PMID:21441352 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Simvastatin results in decreased expression of ITGB1 mRNA; Simvastatin results in decreased expression of ITGB1 protein CTD PMID:17428261 PMID:21874229 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Itgb2 integrin subunit beta 2 affects binding
decreases expression
multiple interactions 		ISO Simvastatin binds to [ITGAL protein binds to ITGB2 protein]
Simvastatin results in decreased expression of ITGB2 mRNA
Simvastatin inhibits the reaction [TNF results in increased expression of ITGB2]
Simvastatin results in decreased expression of [ITGAM protein binds to ITGB2 protein] 		CTD PMID:12615677 PMID:15041742 PMID:21330348 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein decreases expression ISO Simvastatin results in decreased expression of ITGB3BP mRNA CTD PMID:17428261 NCBI chr 5:119,575,657...119,640,974
Ensembl chr 5:119,575,248...119,640,997 		JBrowse link
G Itgb4 integrin subunit beta 4 affects expression
increases expression 		ISO Simvastatin affects the expression of ITGB4 mRNA; Simvastatin affects the expression of ITGB4 protein
Simvastatin results in increased expression of ITGB4 mRNA; Simvastatin results in increased expression of ITGB4 protein 		CTD PMID:14630613 PMID:19110722 NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932 		JBrowse link
G Itgbl1 integrin subunit beta like 1 decreases expression ISO Simvastatin results in decreased expression of ITGBL1 mRNA CTD PMID:17428261 NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098 		JBrowse link
G Jak1 Janus kinase 1 multiple interactions EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK1 protein] CTD PMID:16534557 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions
decreases phosphorylation
decreases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein modified form]; Simvastatin inhibits the reaction [CTF1 results in increased expression of JAK2 protein]; Simvastatin inhibits the reaction [CTF1 results in increased phosphorylation of JAK2 protein]
Simvastatin results in decreased phosphorylation of JAK2 protein
Simvastatin results in decreased expression of JAK2 mRNA 		CTD PMID:16414398 PMID:16534557 PMID:18400235 PMID:19100119 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
increases phosphorylation
decreases localization 		ISO
EXP 		pyrazolanthrone inhibits the reaction [Simvastatin results in increased phosphorylation of JUN protein]
Simvastatin results in decreased expression of JUN mRNA
Simvastatin results in decreased localization of JUN protein
JUN promotes the reaction [Simvastatin results in increased expression of IL12B mRNA]; Simvastatin affects the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [JUN protein binds to JUNB protein binds to FOS protein binds to FOSB protein binds to FOSL2 protein]]; Simvastatin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of JUN protein] 		CTD PMID:12753293 PMID:12963647 PMID:15187114 PMID:15488325 PMID:17125918 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Simvastatin affects the reaction [lipopolysaccharide, E coli O55-B5 promotes the reaction [JUN protein binds to JUNB protein binds to FOS protein binds to FOSB protein binds to FOSL2 protein]] CTD PMID:15187114 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases localization
multiple interactions
decreases activity 		EXP Simvastatin results in decreased localization of KCNH2 protein
Berberine promotes the reaction [Simvastatin results in decreased activity of KCNH2 protein] 		CTD PMID:21525004 PMID:30086269 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kdr kinase insert domain receptor increases expression
multiple interactions 		EXP
ISO 		Simvastatin results in increased expression of KDR mRNA; Simvastatin results in increased expression of KDR protein
Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein] 		CTD PMID:15572054 PMID:19109527 PMID:20821229 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA CTD PMID:28263720 NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812 		JBrowse link
G Klf10 KLF transcription factor 10 multiple interactions ISO [Valsartan co-treated with Simvastatin] inhibits the reaction [AGT protein results in increased expression of KLF10 mRNA] CTD PMID:19225232 NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948 		JBrowse link
G Klf16 KLF transcription factor 16 increases expression ISO Simvastatin results in increased expression of KLF16 mRNA CTD PMID:19262002 NCBI chr 7:9,789,185...9,799,004
Ensembl chr 7:9,775,042...9,798,999 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression
decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased expression of KLF2 mRNA
Simvastatin results in decreased expression of KLF2 mRNA
Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of KLF2 mRNA] 		CTD PMID:17428261 PMID:20493886 PMID:20737288 PMID:22305382 NCBI chr16:17,555,136...17,557,768
Ensembl chr16:17,555,136...17,557,768 		JBrowse link
G Klf6 KLF transcription factor 6 increases expression ISO Simvastatin results in increased expression of KLF6 mRNA CTD PMID:17428261 NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601 		JBrowse link
G Klrb1 killer cell lectin like receptor B1 decreases expression ISO Simvastatin results in decreased expression of KLRF1 mRNA CTD PMID:18192897 NCBI chr 4:164,142,323...164,161,018
Ensembl chr 4:164,142,280...164,161,764 		JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases prenylation ISO Simvastatin results in decreased prenylation of KRAS protein CTD PMID:8063617 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Krt13 keratin 13 increases expression ISO Simvastatin results in increased expression of KRT13 mRNA CTD PMID:17428261 NCBI chr10:85,552,287...85,556,499
Ensembl chr10:85,552,287...85,556,499 		JBrowse link
G Krt15 keratin 15 increases expression ISO Simvastatin results in increased expression of KRT15 mRNA CTD PMID:17428261 NCBI chr10:85,567,197...85,571,014
Ensembl chr10:85,567,202...85,571,142 		JBrowse link
G Krt17 keratin 17 increases expression ISO Simvastatin results in increased expression of KRT17 mRNA CTD PMID:17428261 NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO Simvastatin results in increased expression of LBH mRNA CTD PMID:19262002 NCBI chr 6:28,321,040...28,344,855
Ensembl chr 6:28,321,040...28,370,238 		JBrowse link
G Lbp lipopolysaccharide binding protein decreases expression EXP Simvastatin results in decreased expression of LBP mRNA CTD PMID:16414398 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518 		JBrowse link
G Lcat lecithin cholesterol acyltransferase increases activity
decreases expression 		ISO
EXP 		Simvastatin results in increased activity of LCAT protein
Simvastatin results in decreased expression of LCAT mRNA 		CTD PMID:21241519 PMID:25055962 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
increases expression
increases activity
affects response to substance 		ISO
EXP 		[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB; [Simvastatin co-treated with Ezetimibe] results in increased expression of LDLR mRNA; HMGCR polymorphism promotes the reaction [[LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin] which affects the expression of APOB]; Simvastatin inhibits the reaction [osteum results in decreased expression of LDLR mRNA]
Simvastatin results in increased expression of LDLR mRNA; Simvastatin results in increased expression of LDLR protein
Simvastatin results in increased activity of LDLR protein
Berberine promotes the reaction [Simvastatin results in increased expression of LDLR mRNA]; Simvastatin promotes the reaction [Berberine results in increased expression of LDLR mRNA]
LDLR 3' UTR polymorphism affects the susceptibility to Simvastatin; LDLR mutant form affects the susceptibility to Simvastatin 		CTD PMID:1627634 PMID:8457250 PMID:8593127 PMID:9633944 PMID:10208479 More... NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 increases expression EXP Simvastatin results in increased expression of LEF1 mRNA CTD PMID:19968183 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Lep leptin multiple interactions
decreases secretion
decreases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of LEP protein]; GGTI 298 inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]; GGTI 298 inhibits the reaction [Simvastatin results in decreased secretion of LEP protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased secretion of LEP protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA]
Simvastatin inhibits the reaction [Poloxamer results in increased secretion of LEP protein]
Simvastatin results in decreased expression of LEP mRNA; Simvastatin results in decreased expression of LEP mRNA alternative form 		CTD PMID:19254925 PMID:29071762 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lepr leptin receptor affects response to substance ISO LEPR polymorphism affects the susceptibility to Simvastatin CTD PMID:14625131 PMID:18854995 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of LHB protein]; Simvastatin promotes the reaction [ethinyl estradiol-desogestrel combination results in decreased expression of LHB protein] CTD PMID:17105841 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]] CTD PMID:19225232 NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression EXP Simvastatin results in decreased expression of LITAF mRNA CTD PMID:16414398 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930 		JBrowse link
G Lox lysyl oxidase decreases expression EXP Simvastatin results in decreased expression of LOX mRNA CTD PMID:16414398 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lpl lipoprotein lipase decreases expression
increases expression 		EXP Simvastatin results in decreased expression of LPL
Simvastatin results in increased expression of LPL protein 		CTD PMID:2009092 PMID:19216230 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression EXP Simvastatin results in decreased expression of LRP6 mRNA CTD PMID:25055962 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
G Lrrc2 leucine rich repeat containing 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA CTD PMID:28263720 NCBI chr 8:119,814,514...119,847,587
Ensembl chr 8:119,814,509...119,847,583 		JBrowse link
G Ltb lymphotoxin beta decreases expression ISO Simvastatin results in decreased expression of LTB mRNA CTD PMID:17428261 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Simvastatin results in decreased expression of MAD2L1 mRNA CTD PMID:17428261 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions 		ISO Simvastatin results in increased expression of MAP1LC3B protein
[Simvastatin co-treated with Metformin] results in increased expression of MAP1LC3B protein modified form; Chloroquine promotes the reaction [[Simvastatin co-treated with Metformin] results in increased expression of MAP1LC3B protein modified form] 		CTD PMID:23817226 PMID:25412314 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 decreases expression ISO Simvastatin results in decreased expression of MAP3K14 mRNA CTD PMID:17277159 NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,665,417...88,715,592 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 multiple interactions ISO Simvastatin results in decreased activity of [MAP3K7 protein co-treated with TAB1 protein] CTD PMID:17277159 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases activity 		ISO
EXP 		[tipifarnib co-treated with Simvastatin] results in decreased phosphorylation of MAPK1 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; MAPK1 promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]; MAPK1 promotes the reaction [Simvastatin results in increased expression of NFE2L2 mRNA]; MAPK1 promotes the reaction [Simvastatin results in increased expression of NQO1 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Simvastatin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein
Simvastatin results in decreased phosphorylation of MAPK1 protein
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein]]; Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; Simvastatin inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK1 protein]; Simvastatin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; Simvastatin inhibits the reaction [IGF1 results in increased activity of MAPK1 protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]; Simvastatin results in increased phosphorylation of and results in increased activity of MAPK1 protein
Simvastatin results in increased phosphorylation of MAPK1 protein
Simvastatin results in decreased activity of MAPK1 protein 		CTD PMID:17169357 PMID:17327694 PMID:17428261 PMID:17928392 PMID:18047562 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
decreases expression 		ISO
EXP 		Simvastatin results in increased phosphorylation of and results in increased activity of MAPK14 protein
Simvastatin results in decreased expression of MAPK14 mRNA 		CTD PMID:16414398 PMID:17928392 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation
decreases activity 		ISO
EXP 		[tipifarnib co-treated with Simvastatin] results in decreased phosphorylation of MAPK3 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; Simvastatin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein
Simvastatin results in decreased phosphorylation of MAPK3 protein
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK3 protein]]; Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of MAPK3 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; Simvastatin inhibits the reaction [Smoke analog results in increased phosphorylation of MAPK3 protein]; Simvastatin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; Simvastatin inhibits the reaction [IGF1 results in increased activity of MAPK3 protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]; Simvastatin results in increased phosphorylation of and results in increased activity of MAPK3 protein
Simvastatin results in increased phosphorylation of MAPK3 protein
Simvastatin results in decreased activity of MAPK3 protein 		CTD PMID:17169357 PMID:17327694 PMID:17428261 PMID:17928392 PMID:18047562 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity 		ISO
EXP 		farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]
Simvastatin results in increased activity of MAPK8 protein
Simvastatin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] 		CTD PMID:15187114 PMID:18047562 PMID:18310456 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases activity ISO Simvastatin results in increased activity of MAPK9 protein CTD PMID:15187114 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapt microtubule-associated protein tau affects expression ISO Simvastatin affects the expression of MAPT CTD PMID:19461118 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Mb myoglobin multiple interactions EXP Simvastatin inhibits the reaction [Poloxamer results in increased secretion of MB protein] CTD PMID:29071762 NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO Simvastatin results in decreased expression of MCM4 mRNA CTD PMID:17428261 NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression EXP Simvastatin results in decreased expression of MDH1 protein CTD PMID:20217863 NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases phosphorylation
multiple interactions 		ISO Simvastatin results in increased phosphorylation of MDM2 protein
Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]] 		CTD PMID:15625077 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA CTD PMID:28263720 NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192 		JBrowse link
G Mir221 microRNA 221 decreases expression ISO Simvastatin results in decreased expression of MIR221 CTD PMID:25517390 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:6,023,182...6,023,290 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Simvastatin results in decreased expression of MKI67 protein CTD PMID:26577051 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions
increases expression
decreases secretion
decreases expression 		ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of MMP1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased secretion of MMP1 protein]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP1 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]
Simvastatin results in increased expression of MMP1 mRNA
Simvastatin results in decreased secretion of MMP1 mRNA; Simvastatin results in decreased secretion of MMP1 protein 		CTD PMID:17303772 PMID:17428261 PMID:18625914 PMID:31260663 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Simvastatin results in increased expression of MMP10 mRNA CTD PMID:17428261 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Simvastatin results in increased expression of MMP12 mRNA CTD PMID:17428261 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions 		ISO Simvastatin results in increased expression of MMP13 mRNA
Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA] 		CTD PMID:16274305 PMID:17428261 PMID:31260663 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
increases activity
decreases expression
multiple interactions 		ISO
EXP 		Simvastatin results in decreased activity of MMP2 protein
Simvastatin results in increased activity of MMP2 protein
Simvastatin results in decreased expression of MMP2 protein
Simvastatin results in decreased expression of MMP2 mRNA
Simvastatin affects the reaction [IL1B protein results in increased activity of MMP2 protein]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP2 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]
Simvastatin inhibits the reaction [Monocrotaline results in increased expression of MMP2 mRNA]; Simvastatin results in decreased expression of and results in decreased activity of MMP2 protein 		CTD PMID:15210533 PMID:17038636 PMID:17158816 PMID:17169357 PMID:18309148 More... NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp28 matrix metallopeptidase 28 increases expression ISO Simvastatin results in increased expression of MMP28 mRNA CTD PMID:17428261 NCBI chr10:68,738,651...68,762,377
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression
multiple interactions 		EXP
ISO 		Simvastatin results in decreased expression of MMP3 mRNA
Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA] 		CTD PMID:16414398 PMID:31260663 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826 		JBrowse link
G Mmp8 matrix metallopeptidase 8 multiple interactions ISO Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP8 mRNA] CTD PMID:18625914 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases activity
decreases expression
decreases activity 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; Simvastatin inhibits the reaction [IL1B protein results in increased activity of MMP9 protein]; Simvastatin inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of MMP9 protein]; Simvastatin promotes the reaction [TNF results in increased expression of MMP9 mRNA]
Simvastatin results in increased activity of MMP9 protein
Simvastatin results in decreased expression of MMP9 mRNA; Simvastatin results in decreased expression of MMP9 protein
Simvastatin results in decreased activity of MMP9 protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]]; Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of MMP9 protein]; Simvastatin inhibits the reaction [Smoke analog results in increased activity of MMP9 protein]; Simvastatin inhibits the reaction [Smoke analog results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Smoke analog results in increased secretion of MMP9 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Simvastatin results in decreased expression of and results in decreased activity of MMP9 protein
Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of MMP9 protein] 		CTD PMID:15107580 PMID:15210533 PMID:15537504 PMID:15728660 PMID:16002570 More... NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
decreases expression 		ISO
EXP 		Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]
1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]
Simvastatin results in decreased activity of MPO protein
Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]
Simvastatin results in decreased expression of MPO protein 		CTD PMID:15665042 PMID:17038636 PMID:21764683 PMID:33774062 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mras muscle RAS oncogene homolog multiple interactions EXP Simvastatin inhibits the reaction [Glucose results in increased activity of MRAS protein]; Simvastatin inhibits the reaction [Smoke analog results in increased activity of MRAS protein] CTD PMID:18569938 PMID:19299917 NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911 		JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 decreases response to substance ISO MRPS31 SNP results in decreased susceptibility to Simvastatin CTD PMID:21483694 NCBI chr16:76,303,807...76,332,970
Ensembl chr16:76,301,645...76,333,065 		JBrowse link
G Mstn myostatin multiple interactions
increases expression 		ISO 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid inhibits the reaction [Simvastatin results in increased expression of MSTN protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of MSTN protein]; IRF4 protein inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; IRF4 protein inhibits the reaction [Simvastatin results in increased expression of MSTN protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of MSTN mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of MSTN protein]; Simvastatin results in increased expression of and results in increased secretion of MSTN protein
Simvastatin results in increased expression of MSTN mRNA; Simvastatin results in increased expression of MSTN protein 		CTD PMID:33034787 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:55,944,513...55,950,913 		JBrowse link
G Mt1a metallothionein 1A increases expression EXP Simvastatin results in increased expression of MT1A mRNA CTD PMID:19001041 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase multiple interactions
increases expression
affects response to substance 		ISO Homocysteine inhibits the reaction [Simvastatin results in increased expression of MTHFR protein modified form]; Simvastatin promotes the reaction [Homocysteine results in increased expression of MTHFR protein]
MTHFR gene mutant form inhibits the reaction [Simvastatin results in increased expression of APOA1 protein]; MTHFR inhibits the reaction [Simvastatin results in increased expression of NOS2 mRNA]; MTHFR inhibits the reaction [Simvastatin results in increased expression of NOS2 protein]
MTHFR affects the susceptibility to Simvastatin 		CTD PMID:18540024 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions 		ISO
EXP 		Simvastatin results in decreased phosphorylation of MTOR protein
Simvastatin inhibits the reaction [Dietary Fats results in increased expression of MTOR mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in increased phosphorylation of MTOR protein]
FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of MTOR protein] 		CTD PMID:22144680 PMID:33034787 PMID:39536891 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP
ISO 		Simvastatin inhibits the reaction [Acrolein results in increased expression of MUC5AC mRNA]; Simvastatin inhibits the reaction [Acrolein results in increased expression of MUC5AC protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased expression of MUC5AC protein]]; Simvastatin inhibits the reaction [Acrolein results in increased expression of MUC5AC protein] 		CTD PMID:19024099 PMID:20359552 NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP Simvastatin results in increased expression of MVD mRNA CTD PMID:25055962 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Mvk mevalonate kinase increases expression
multiple interactions 		EXP
ISO 		Simvastatin results in increased expression of MVK mRNA
[MVK gene mutant form results in increased activity of HMGCR protein] which results in increased susceptibility to Simvastatin; MVK gene mutant form promotes the reaction [Simvastatin results in decreased activity of HMGCR protein]; MVK gene mutant form promotes the reaction [Simvastatin results in decreased farnesylation of and affects the localization of HRAS protein]; MVK gene mutant form promotes the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein] 		CTD PMID:12477733 PMID:25055962 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503 		JBrowse link
G Mybph myosin binding protein H increases expression ISO Simvastatin results in increased expression of MYBPH mRNA CTD PMID:17183729 NCBI chr13:48,205,162...48,212,928
Ensembl chr13:48,205,269...48,212,928 		JBrowse link
G Myh10 myosin heavy chain 10 decreases expression ISO Simvastatin results in decreased expression of MYH10 protein CTD PMID:16005304 NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036 		JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Simvastatin results in increased expression of MYH6 mRNA CTD PMID:19262002 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression EXP Simvastatin results in decreased expression of NDRG1 protein CTD PMID:20217863 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 multiple interactions
increases localization
decreases localization 		ISO Simvastatin promotes the reaction [NFATC3 protein binds to BCL2 promoter]
Simvastatin results in increased localization of NFATC3 protein
Simvastatin results in decreased localization of NFATC3 protein alternative form 		CTD PMID:20369390 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases localization
increases expression
multiple interactions 		ISO
EXP 		Simvastatin results in increased localization of NFE2L2 protein
Simvastatin results in increased expression of NFE2L2 mRNA
MAPK1 promotes the reaction [Simvastatin results in increased expression of NFE2L2 mRNA]; Simvastatin results in increased expression of and affects the localization of NFE2L2 protein
Mevalonic Acid affects the reaction [Simvastatin results in increased localization of NFE2L2 protein]
NFE2L2 mutant form inhibits the reaction [Glucose deficiency promotes the reaction [Simvastatin results in increased expression of HMOX1 mRNA]] 		CTD PMID:17928392 PMID:18787804 PMID:30513525 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases expression
decreases activity
decreases localization
increases localization 		ISO
EXP 		artemisinin inhibits the reaction [Simvastatin results in increased localization of and results in increased activity of NFKB1 protein]; artemisinin inhibits the reaction [Simvastatin results in increased localization of NFKB1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; parthenolide inhibits the reaction [Simvastatin results in increased localization of and results in increased activity of NFKB1 protein]; parthenolide inhibits the reaction [Simvastatin results in increased localization of NFKB1 protein]; RHOA protein affects the reaction [Simvastatin results in increased localization of and results in increased activity of NFKB1 protein]; Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Simvastatin promotes the reaction [Doxorubicin results in increased localization of and results in increased activity of NFKB1 protein]; Simvastatin promotes the reaction [Doxorubicin results in increased localization of NFKB1 protein]; Simvastatin results in increased localization of and results in increased activity of NFKB1 protein
Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]]
Simvastatin results in decreased expression of NFKB1 mRNA
Simvastatin results in decreased activity of NFKB1 protein
Simvastatin results in decreased localization of NFKB1 protein 		CTD PMID:12753293 PMID:17038636 PMID:17277159 PMID:18463201 PMID:21465237 More... NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases phosphorylation 		ISO
EXP 		artemisinin inhibits the reaction [Simvastatin results in increased phosphorylation of NFKBIA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; parthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]; Simvastatin promotes the reaction [Doxorubicin results in increased phosphorylation of NFKBIA protein]
[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased phosphorylation of NFKBIA protein; Simvastatin inhibits the reaction [IL1A results in decreased expression of NFKBIA protein modified form]; Simvastatin inhibits the reaction [Smoke analog results in increased phosphorylation of NFKBIA protein]
[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which results in increased phosphorylation of NFKBIA protein; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]] 		CTD PMID:15705589 PMID:17075836 PMID:17178392 PMID:17277159 PMID:18073186 More... NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nlgn3 neuroligin 3 multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of NLGN3 mRNA] CTD PMID:16373842 NCBI chr  X:70,469,251...70,497,380
Ensembl chr  X:70,469,457...70,497,379 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein]]; Simvastatin inhibits the reaction [Acetic Acid results in increased expression of NLRP3 mRNA]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] CTD PMID:30408459 PMID:35762198 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nog noggin multiple interactions EXP NOG inhibits the reaction [Simvastatin results in increased expression of ACAN mRNA]; NOG inhibits the reaction [Simvastatin results in increased expression of COL2A1 mRNA] CTD PMID:18628692 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
increases expression 		ISO
EXP 		Simvastatin promotes the reaction [Doxorubicin results in increased expression of NOS2 protein]
Simvastatin results in decreased expression of NOS2 mRNA; Simvastatin results in decreased expression of NOS2 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in decreased expression of NOS2 protein]]; Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of NOS2 mRNA]; Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of NOS2 protein]; Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]; Simvastatin inhibits the reaction [IL1A results in increased expression of NOS2 mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]; Simvastatin inhibits the reaction [TNF results in decreased expression of NOS2 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of NOS2 mRNA]; Y 27632 inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in decreased expression of NOS2 protein]]
Simvastatin results in increased expression of NOS2 mRNA; Simvastatin results in increased expression of NOS2 protein
Homocysteine affects the reaction [Simvastatin results in increased expression of NOS2 protein]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of NOS2 mRNA]]; MTHFR inhibits the reaction [Simvastatin results in increased expression of NOS2 mRNA]; MTHFR inhibits the reaction [Simvastatin results in increased expression of NOS2 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of NOS2 mRNA]; Simvastatin promotes the reaction [Homocysteine results in increased expression of NOS2 mRNA]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] 		CTD PMID:10188333 PMID:11470468 PMID:15705589 PMID:16414398 PMID:17729120 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
decreases expression
multiple interactions
increases phosphorylation 		ISO
EXP 		Simvastatin results in increased expression of NOS3; Simvastatin results in increased expression of NOS3 mRNA; Simvastatin results in increased expression of NOS3 protein
Simvastatin results in decreased expression of NOS3 mRNA; Simvastatin results in decreased expression of NOS3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; [Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of NOS3 mRNA]; Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]; Nifedipine promotes the reaction [Simvastatin inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]]; Simvastatin inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]; Simvastatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 mRNA]; Simvastatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein]; Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [[Hydrogen Peroxide results in decreased expression of NOS3 protein] which results in decreased secretion of Nitric Oxide]]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 mRNA]]; Simvastatin promotes the reaction [Nifedipine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NOS3 protein]]; Wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]]; Wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]]
Simvastatin results in increased phosphorylation of NOS3 protein
Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in decreased expression of NOS3 protein]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of NOS3 mRNA]; Simvastatin inhibits the reaction [Smoke analog affects the expression of NOS3 mRNA]; Simvastatin results in increased expression of and results in increased phosphorylation of and results in increased activity of NOS3 protein 		CTD PMID:10188333 PMID:11470468 PMID:11947894 PMID:12379581 PMID:12406854 More... NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Notch1 notch receptor 1 increases cleavage
increases expression 		EXP Simvastatin results in increased cleavage of NOTCH1 protein
Simvastatin results in increased expression of NOTCH1 mRNA 		CTD PMID:19109527 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613 		JBrowse link
G Notch4 notch receptor 4 increases expression EXP Simvastatin results in increased expression of NOTCH4 mRNA CTD PMID:19109527 NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072 		JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 decreases expression ISO Simvastatin results in decreased expression of NPC1L1 mRNA CTD PMID:17980884 NCBI chr14:85,285,387...85,305,050
Ensembl chr14:85,285,390...85,305,050 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin increases expression ISO Simvastatin results in increased expression of NPHS2 mRNA CTD PMID:16710349 NCBI chr13:70,993,622...71,011,585
Ensembl chr13:70,999,186...71,011,572 		JBrowse link
G Nppa natriuretic peptide A multiple interactions
decreases expression 		EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of NPPA mRNA]
Simvastatin results in decreased expression of NPPA mRNA 		CTD PMID:16029635 PMID:16534557 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B decreases expression EXP Simvastatin results in decreased expression of NPPB; Simvastatin results in decreased expression of NPPB protein CTD PMID:16628357 PMID:21124329 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression 		ISO MAPK1 promotes the reaction [Simvastatin results in increased expression of NQO1 mRNA]
Simvastatin results in increased expression of NQO1 mRNA; Simvastatin results in increased expression of NQO1 protein 		CTD PMID:30513525 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of NR0B1 mRNA CTD PMID:25055962 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of NR1D1 mRNA] CTD PMID:16373842 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases expression ISO Simvastatin results in decreased expression of NR1H3 mRNA CTD PMID:22160096 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP Simvastatin affects the reaction [Dietary Fats affects the expression of NR1H4 mRNA]; Simvastatin affects the reaction [Dietary Fats affects the expression of NR1H4 protein] CTD PMID:33383043 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions 		ISO Simvastatin results in increased activity of NR1I2 protein
[Simvastatin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Simvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Simvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose; [Simvastatin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; SGK2 mutant form inhibits the reaction [[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose]; Simvastatin promotes the reaction [NR1I2 protein binds to SGK2 promoter] 		CTD PMID:15802384 PMID:17041008 PMID:24204015 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO
EXP 		Simvastatin results in increased activity of NR1I3 protein CTD PMID:15802384 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of NR4A3 mRNA] CTD PMID:16005304 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Nrp1 neuropilin 1 decreases response to substance ISO NRP1 SNP results in decreased susceptibility to Simvastatin CTD PMID:21483694 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL decreases expression EXP Simvastatin results in decreased expression of NSDHL mRNA CTD PMID:25055962 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA CTD PMID:28263720 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA CTD PMID:28263720 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,564,570...5,874,628 		JBrowse link
G Ocln occludin increases expression EXP Simvastatin results in increased expression of OCLN CTD PMID:18544044 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression EXP Simvastatin results in decreased expression of OLR1 mRNA CTD PMID:16414398 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Osbpl1a oxysterol binding protein-like 1A decreases expression EXP Simvastatin results in decreased expression of OSBPL1A mRNA CTD PMID:25055962 NCBI chr18:4,178,734...4,383,511
Ensembl chr18:4,179,631...4,369,421 		JBrowse link
G Osm oncostatin M multiple interactions ISO Simvastatin inhibits the reaction [CCN1 results in increased expression of OSM]; Simvastatin inhibits the reaction [OSM results in increased expression of CCN1 mRNA]; Simvastatin inhibits the reaction [OSM results in increased phosphorylation of CREB1 protein] CTD PMID:20191585 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression EXP Simvastatin results in decreased expression of P4HB mRNA CTD PMID:16414398 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
decreases cleavage 		ISO
EXP 		[Simvastatin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]; Mevalonic Acid inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]; pifithrin inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]; Simvastatin inhibits the reaction [Coal Ash results in increased expression of PARP1 protein modified form]; Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]
IGF1 protein inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]
Simvastatin inhibits the reaction [Glucose results in increased activity of PARP1 protein]
Simvastatin results in decreased cleavage of PARP1 mRNA 		CTD PMID:16054375 PMID:18004065 PMID:20045437 PMID:20464445 PMID:21910007 More... NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Simvastatin results in decreased expression of PCNA mRNA; Simvastatin results in decreased expression of PCNA protein CTD PMID:17428261 PMID:18824851 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 multiple interactions ISO [Simvastatin co-treated with Ezetimibe] results in increased expression of PCSK9 mRNA CTD PMID:17980884 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pde4b phosphodiesterase 4B multiple interactions ISO Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of PDE4B mRNA] CTD PMID:16373842 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pdgfa platelet derived growth factor subunit A decreases expression EXP Simvastatin results in decreased expression of PDGFA mRNA CTD PMID:16414398 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdgfb platelet derived growth factor subunit B decreases expression
decreases activity
multiple interactions 		EXP
ISO 		Simvastatin results in decreased expression of PDGFB protein
Simvastatin results in decreased expression of PDGFB mRNA
Simvastatin results in decreased activity of PDGFB protein
Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of PDGFB mRNA]
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased activity of PDGFB protein]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein] 		CTD PMID:8231022 PMID:10412745 PMID:10412775 PMID:15728660 PMID:16373842 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression EXP Simvastatin results in decreased expression of PDGFRA mRNA CTD PMID:16414398 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression
multiple interactions 		ISO Simvastatin results in decreased expression of PDGFRB mRNA
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA 		CTD PMID:10412775 PMID:28263720 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 increases expression EXP Simvastatin results in increased expression of PDK2 mRNA CTD PMID:19001041 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP
ISO 		Simvastatin results in increased expression of PDK4 mRNA CTD PMID:19001041 PMID:19262002 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Simvastatin results in increased expression of PECAM1 mRNA CTD PMID:19109527 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Phb2 prohibitin 2 decreases expression EXP Simvastatin results in decreased expression of PHB2 protein CTD PMID:20217863 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:159,203,926...159,209,231 		JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C decreases expression ISO Simvastatin results in decreased expression of PIGC mRNA CTD PMID:19262002 NCBI chr13:76,876,894...76,879,420
Ensembl chr13:76,872,922...76,880,224 		JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO Simvastatin results in decreased expression of PITX2 mRNA CTD PMID:19262002 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 decreases expression ISO Simvastatin results in decreased expression of PKMYT1 mRNA CTD PMID:17428261 NCBI chr10:13,252,805...13,263,584
Ensembl chr10:13,252,816...13,264,263 		JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions EXP Simvastatin inhibits the reaction [Cholesterol, Dietary results in increased expression of PLA2G2A protein] CTD PMID:19237014 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g7 phospholipase A2 group VII multiple interactions ISO Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G7 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G7 mRNA] CTD PMID:21176638 NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747 		JBrowse link
G Plat plasminogen activator, tissue type multiple interactions
decreases expression
increases activity
increases expression 		ISO
EXP 		geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT mRNA]; geranylgeraniol inhibits the reaction [Simvastatin results in increased expression of PLAT]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of PLAT mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of PLAT]; Simvastatin inhibits the reaction [TNF results in decreased expression of PLAT]
Simvastatin results in decreased expression of PLAT mRNA
Simvastatin results in increased activity of PLAT protein
Simvastatin results in increased expression of PLAT; Simvastatin results in increased expression of PLAT mRNA; Simvastatin results in increased expression of PLAT protein 		CTD PMID:12371961 PMID:12753293 PMID:16414398 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Simvastatin results in decreased expression of PLAU mRNA CTD PMID:10412775 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plcg2 phospholipase C, gamma 2 increases expression ISO Simvastatin results in increased expression of PLCG2 mRNA CTD PMID:17428261 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684 		JBrowse link
G Plk2 polo-like kinase 2 decreases expression ISO Simvastatin results in decreased expression of PLK2 mRNA CTD PMID:19262002 NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 decreases expression EXP Simvastatin results in decreased expression of PLOD3 mRNA CTD PMID:16414398 NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631 		JBrowse link
G Plxnd1 plexin D1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA CTD PMID:28263720 NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 affects localization
increases expression
multiple interactions 		ISO Simvastatin affects the localization of PMAIP1 protein
Simvastatin results in increased expression of PMAIP1 mRNA; Simvastatin results in increased expression of PMAIP1 protein
pifithrin inhibits the reaction [Simvastatin results in increased expression of PMAIP1 mRNA] 		CTD PMID:20045437 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Pmvk phosphomevalonate kinase increases expression EXP Simvastatin results in increased expression of PMVK mRNA CTD PMID:25055962 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080 		JBrowse link
G Pomt1 protein-O-mannosyltransferase 1 increases expression ISO Simvastatin results in increased expression of POMT1 mRNA CTD PMID:19262002 NCBI chr 3:35,918,370...35,936,330
Ensembl chr 3:35,918,188...35,936,364 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions
increases expression 		ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA]; PON1 gene polymorphism affects the reaction [Simvastatin results in increased abundance of Cholesterol, HDL]; PON1 gene SNP affects the reaction [Simvastatin results in increased abundance of Cholesterol, HDL]; PON1 protein affects the reaction [Simvastatin results in increased abundance of Cholesterol, HDL]; Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]; Simvastatin results in increased expression of and results in increased activity of PON1 protein; Squalene inhibits the reaction [Simvastatin results in increased expression of PON1 mRNA] CTD PMID:14500290 PMID:15690306 PMID:16238680 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
multiple interactions 		EXP
ISO 		Simvastatin results in increased expression of PPARA mRNA
Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of PPARA mRNA]; Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of PPARA protein]; Simvastatin promotes the reaction [Zymosan results in increased expression of PPARA]
PPARA mutant form inhibits the reaction [Simvastatin results in increased expression of SCARB1]; Simvastatin promotes the reaction [TNF results in increased expression of PPARA] 		CTD PMID:15234187 PMID:18981156 PMID:19001041 PMID:20835264 PMID:21323892 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression 		ISO
EXP 		[2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [Simvastatin results in decreased expression of CCR2 mRNA]; [2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [Simvastatin results in decreased expression of CCR2 protein]
Simvastatin results in decreased expression of PPARG
Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of PPARG mRNA]; Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of PPARG protein] 		CTD PMID:15781755 PMID:19216230 PMID:20835264 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]]; Simvastatin inhibits the reaction [Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R12A protein]]; Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein] CTD PMID:24449418 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157 		JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A multiple interactions EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R14A protein]]; Simvastatin inhibits the reaction [Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R14A protein]]; Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R14A protein] CTD PMID:24449418 NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147 		JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO Simvastatin results in decreased expression of PRIM1 mRNA CTD PMID:17428261 NCBI chr 7:1,031,436...1,047,134 JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases expression
multiple interactions 		EXP
ISO 		Simvastatin results in increased expression of PRKAA1 mRNA
Simvastatin inhibits the reaction [osteum results in decreased expression of PRKAA1 mRNA] 		CTD PMID:25055962 PMID:33596472 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Psen1 presenilin 1 increases expression EXP Simvastatin results in increased expression of PSEN1 mRNA CTD PMID:19109527 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189 		JBrowse link
G Ptafr platelet-activating factor receptor decreases expression EXP Simvastatin results in decreased expression of PTAFR mRNA CTD PMID:16414398 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408 		JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Simvastatin results in increased expression of PTEN mRNA; Simvastatin results in increased expression of PTEN protein CTD PMID:20060890 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions
decreases expression 		ISO Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES protein]
Simvastatin results in decreased expression of PTGES protein 		CTD PMID:17038636 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
increases expression 		ISO
EXP 		JTE 013 inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]]; Simvastatin inhibits the reaction [IFNG results in increased expression of PTGS2]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Simvastatin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of PTGS2 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of PTGS2 protein]; Simvastatin promotes the reaction [Glucose promotes the reaction [AGT protein results in increased expression of PTGS2 mRNA]]; Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]; Suramin inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]]
Simvastatin inhibits the reaction [Acetic Acid results in increased expression of PTGS2 protein]
Simvastatin results in decreased expression of PTGS2 protein
Simvastatin results in increased expression of PTGS2 mRNA
Simvastatin promotes the reaction [IFNG results in increased expression of PTGS2] 		CTD PMID:17038636 PMID:17277159 PMID:17901590 PMID:18612546 PMID:19225232 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases activity ISO Simvastatin results in decreased activity of PTK2 protein CTD PMID:17428261 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Pxn paxillin multiple interactions
decreases phosphorylation
affects localization 		EXP Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]]; Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of PXN protein]
Simvastatin results in decreased phosphorylation of PXN protein
Simvastatin affects the localization of PXN protein 		CTD PMID:22306966 NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions
decreases activity
increases activity
decreases expression
increases expression
affects localization 		ISO
EXP 		Cholesterol inhibits the reaction [Simvastatin affects the localization of and results in decreased activity of RAC1 protein]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]]; Simvastatin affects the localization of and results in decreased activity of RAC1 protein; Simvastatin inhibits the reaction [AGT results in increased activity of RAC1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased activity of RAC1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased localization of RAC1 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased prenylation of RAC1 protein]
Simvastatin results in decreased activity of RAC1 protein
Simvastatin results in increased activity of RAC1 protein
Simvastatin results in decreased expression of RAC1
Simvastatin results in increased expression of RAC1 protein
Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of RAC1 protein]
Simvastatin affects the localization of RAC1 protein 		CTD PMID:16698853 PMID:17169357 PMID:17303772 PMID:17513949 PMID:18625914 More... NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rac2 Rac family small GTPase 2 affects localization
decreases activity 		ISO Simvastatin affects the localization of RAC2 protein
Simvastatin results in decreased activity of RAC2 protein 		CTD PMID:17169357 PMID:20045437 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Rac3 Rac family small GTPase 3 affects localization ISO Simvastatin affects the localization of RAC3 protein CTD PMID:20045437 NCBI chr10:106,501,133...106,503,569
Ensembl chr10:106,501,135...106,503,569 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO Simvastatin results in decreased expression of RACGAP1 mRNA CTD PMID:17428261 NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases activity
multiple interactions 		ISO
EXP 		Simvastatin results in decreased activity of RAF1 protein
Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein] 		CTD PMID:18569938 PMID:19360310 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases prenylation
decreases expression
decreases geranoylation
multiple interactions 		ISO Simvastatin results in decreased prenylation of RAP1A protein
Simvastatin results in decreased expression of RAP1A protein alternative form
Simvastatin results in decreased geranoylation of RAP1A protein
Simvastatin results in decreased geranoylation of and results in decreased prenylation of RAP1A protein
Mevalonic Acid inhibits the reaction [Simvastatin results in decreased geranoylation of RAP1A protein]; Simvastatin results in decreased geranoylation of and results in decreased prenylation of RAP1A protein 		CTD PMID:20018177 PMID:22120639 PMID:25578243 PMID:37956312 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects phosphorylation
affects localization 		ISO Simvastatin affects the phosphorylation of RASGRF1 protein
Simvastatin affects the localization of RASGRF1 protein 		CTD PMID:20417880 NCBI chr 8:99,324,986...99,454,099
Ensembl chr 8:99,324,749...99,454,089 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO
EXP 		Simvastatin results in decreased phosphorylation of RB1 protein CTD PMID:17928568 PMID:18804536 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
decreases localization
increases localization 		ISO
EXP 		artemisinin inhibits the reaction [Simvastatin results in increased localization of and results in increased activity of RELA protein]; artemisinin inhibits the reaction [Simvastatin results in increased localization of RELA protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; parthenolide inhibits the reaction [Simvastatin results in increased localization of and results in increased activity of RELA protein]; parthenolide inhibits the reaction [Simvastatin results in increased localization of RELA protein]; RHOA protein affects the reaction [Simvastatin results in increased localization of and results in increased activity of RELA protein]; Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Simvastatin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]; Simvastatin inhibits the reaction [TNF results in increased localization of RELA protein]; Simvastatin promotes the reaction [Doxorubicin results in increased localization of and results in increased activity of RELA protein]; Simvastatin promotes the reaction [Doxorubicin results in increased localization of RELA protein]; Simvastatin results in increased localization of and results in increased activity of RELA protein
Simvastatin results in decreased expression of RELA protein
Simvastatin results in decreased expression of RELA mRNA; Simvastatin results in decreased expression of RELA protein
Simvastatin results in decreased localization of RELA protein
[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which affects the localization of RELA protein; Homocysteine inhibits the reaction [Simvastatin results in decreased expression of RELA protein]; Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]; Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein modified form]; Simvastatin promotes the reaction [IFNG promotes the reaction [RELA binds to CD40 promoter]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of [RELA protein binds to NFKB1 protein]]]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein modified form]]
[[Simvastatin co-treated with Lipopolysaccharides] results in increased expression of HMOX1 protein] which affects the localization of RELA protein; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]]; Simvastatin inhibits the reaction [Dietary Fats results in increased expression of RELA mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in increased expression of RELA protein]; Simvastatin inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Simvastatin inhibits the reaction [IL1A results in increased localization of RELA protein]; Simvastatin inhibits the reaction [Smoke analog results in increased phosphorylation of RELA protein] 		CTD PMID:12753293 PMID:15705589 PMID:16414398 PMID:17038636 PMID:17075836 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556 		JBrowse link
G Retn resistin multiple interactions ISO geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein]]; Simvastatin inhibits the reaction [CRP results in increased expression of RETN mRNA]; Simvastatin inhibits the reaction [CRP results in increased secretion of RETN protein] CTD PMID:18023360 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:6,508,801...6,511,116 		JBrowse link
G Rfc5 replication factor C subunit 5 decreases expression ISO Simvastatin results in decreased expression of RFC5 mRNA CTD PMID:17428261 NCBI chr12:44,868,322...44,877,879
Ensembl chr12:44,862,329...44,878,151 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression ISO Simvastatin results in increased expression of RGS2 mRNA CTD PMID:17428261 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697 		JBrowse link
G Rhoa ras homolog family member A multiple interactions
decreases prenylation
affects localization
increases expression
increases localization
decreases expression
decreases activity 		ISO
EXP 		farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]; geranylgeraniol inhibits the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin affects the localization of and results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased activity of RHOA protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased localization of RHOA protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased activity of RHOA protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased localization of RHOA protein]; MVK gene mutant form promotes the reaction [Simvastatin results in decreased geranoylation of and affects the localization of RHOA protein]; RHOA inhibits the reaction [Simvastatin results in increased expression of SCARB1]; RHOA protein affects the reaction [Simvastatin results in increased localization of and results in increased activity of NFKB1 protein]; RHOA protein affects the reaction [Simvastatin results in increased localization of and results in increased activity of RELA protein]; Simvastatin affects the localization of and results in decreased activity of RHOA protein; Simvastatin inhibits the reaction [geranylgeranyl pyrophosphate affects the localization of RHOA protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in decreased activity of RHOA protein]; Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]; Simvastatin results in decreased localization of and results in decreased activity of RHOA protein; Simvastatin results in increased localization of and results in decreased prenylation of RHOA protein
Simvastatin results in decreased prenylation of RHOA protein
Simvastatin affects the localization of RHOA protein
Simvastatin results in increased expression of RHOA protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]
Simvastatin results in increased expression of RHOA mRNA
Simvastatin results in decreased expression of RHOA; Simvastatin results in decreased expression of RHOA protein
geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of RHOA protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of RHOA]; Simvastatin inhibits the reaction [Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R12A protein]]; Simvastatin inhibits the reaction [Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R14A protein]]; Simvastatin inhibits the reaction [Phenylephrine results in increased activity of RHOA protein]; Simvastatin results in decreased geranoylation of and results in decreased prenylation of RHOA protein 		CTD PMID:12477733 PMID:14630613 PMID:15200425 PMID:16005304 PMID:16470222 More... NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rhoc ras homolog family member C increases expression ISO Simvastatin results in increased expression of RHOC mRNA CTD PMID:14630613 NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]; [Simvastatin co-treated with Metformin] results in increased expression of RIPK1 protein; necrostatin-1 inhibits the reaction [[Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]]; RIPK3 protein affects the reaction [necrostatin-1 inhibits the reaction [[Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]]] CTD PMID:25412314 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions ISO [Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]; necrostatin-1 inhibits the reaction [[Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]]; RIPK3 protein affects the reaction [necrostatin-1 inhibits the reaction [[Simvastatin co-treated with Metformin] promotes the reaction [RIPK3 protein binds to RIPK1 protein]]] CTD PMID:25412314 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025 		JBrowse link
G Rorc RAR-related orphan receptor C multiple interactions
decreases expression 		ISO IFNG affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; IL27 affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; IL4 affects the reaction [Simvastatin results in decreased expression of RORC mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of RORC mRNA] CTD PMID:18453621 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Rpl39 ribosomal protein L39 increases expression ISO Simvastatin results in increased expression of RPL39 mRNA CTD PMID:19262002 NCBI chr  X:121,192,901...121,195,896
Ensembl chr 7:31,721,884...31,722,039
Ensembl chr15:31,721,884...31,722,039
Ensembl chr  X:31,721,884...31,722,039 		JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Simvastatin results in increased expression of RPS10 mRNA CTD PMID:19262002 NCBI chr20:5,696,135...5,700,863
Ensembl chr20:5,696,135...5,700,150
Ensembl chr 6:5,696,135...5,700,150 		JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
decreases phosphorylation 		ISO IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6 protein] CTD PMID:27734117 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation 		ISO FST protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein]; IGF1 protein inhibits the reaction [Simvastatin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:27734117 PMID:33034787 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 affects expression ISO Simvastatin affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO Simvastatin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 affects expression ISO Simvastatin affects the expression of HLA-F mRNA CTD PMID:25811541 NCBI chr20:3,407,880...3,484,130 JBrowse link
G RT1-Da RT1 class II, locus Da multiple interactions ISO Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA protein]]; Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of HLA-DRA protein] CTD PMID:11219190 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-DMa RT1 class II, locus DMa decreases expression EXP Simvastatin results in decreased expression of RT1-DMA mRNA CTD PMID:16414398 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335 		JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression
multiple interactions 		ISO Simvastatin results in increased expression of RUNX2
Simvastatin results in increased expression of RUNX2 mRNA
DKK1 inhibits the reaction [Simvastatin results in increased expression of RUNX2 mRNA]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; Simvastatin inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]; Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]] 		CTD PMID:18310456 PMID:20381859 PMID:20417880 PMID:22058016 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Ryr2 ryanodine receptor 2 increases expression EXP Simvastatin results in increased expression of RYR2 mRNA; Simvastatin results in increased expression of RYR2 protein CTD PMID:15916736 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression
multiple interactions 		ISO Simvastatin results in increased expression of S100A6 mRNA
Simvastatin results in increased expression of S100A6 mRNA; Simvastatin results in increased expression of S100A6 protein
Simvastatin results in increased expression of and results in increased localization of S100A6 protein 		CTD PMID:14973129 PMID:17428261 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Simvastatin results in increased expression of S100A8 mRNA CTD PMID:17428261 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Simvastatin results in increased expression of S100A9 mRNA CTD PMID:17428261 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO Simvastatin results in increased expression of S1PR1 mRNA CTD PMID:18612546 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 increases expression
decreases expression 		ISO Simvastatin results in increased expression of S1PR3 mRNA
Simvastatin results in decreased expression of S1PR3 mRNA 		CTD PMID:18612546 PMID:18981156 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197 		JBrowse link
G Scap SREBF chaperone affects response to substance ISO SCAP polymorphism affects the susceptibility to Simvastatin CTD PMID:16158080 NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
increases expression 		ISO
EXP 		PPARA mutant form inhibits the reaction [Simvastatin results in increased expression of SCARB1]; RHOA inhibits the reaction [Simvastatin results in increased expression of SCARB1]
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SCARB1 mRNA; Simvastatin inhibits the reaction [Dietary Fats results in decreased expression of SCARB1 mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in decreased expression of SCARB1 protein]
Simvastatin results in increased expression of SCARB1; Simvastatin results in increased expression of SCARB1 mRNA; Simvastatin results in increased expression of SCARB1 protein 		CTD PMID:18981156 PMID:20025956 PMID:21241519 PMID:25055962 PMID:33383043 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Sdc1 syndecan 1 decreases expression EXP Simvastatin results in decreased expression of SDC1 mRNA CTD PMID:16414398 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500 		JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Simvastatin results in decreased expression of SDC4 mRNA CTD PMID:16414398 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
G Sele selectin E multiple interactions
affects expression
decreases expression 		ISO farnesyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]]; Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE mRNA]; Simvastatin promotes the reaction [IL1B protein results in increased expression of SELE protein]; Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]; Vitamin E inhibits the reaction [Simvastatin results in decreased expression of SELE protein modified form]
Simvastatin affects the expression of SELE protein 		CTD PMID:10946302 PMID:14602771 PMID:16740276 PMID:21994025 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Selp selectin P multiple interactions
decreases expression 		EXP Simvastatin inhibits the reaction [staphylococcal alpha-toxin results in increased expression of SELP protein]
Simvastatin results in decreased expression of SELP mRNA 		CTD PMID:12379581 PMID:16414398 NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression
decreases secretion
decreases activity
multiple interactions 		ISO
EXP 		Simvastatin results in decreased expression of SERPINE1 mRNA; Simvastatin results in decreased expression of SERPINE1 protein
Simvastatin results in decreased secretion of SERPINE1 protein
Simvastatin results in decreased activity of SERPINE1 protein
[Simvastatin co-treated with Dexamethasone] results in increased secretion of SERPINE1 protein 		CTD PMID:16375908 PMID:16414398 PMID:17513194 PMID:21524281 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sesn2 sestrin 2 increases expression ISO Simvastatin results in increased expression of SESN2 mRNA CTD PMID:19262002 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255 		JBrowse link
G Sesn3 sestrin 3 decreases expression ISO Simvastatin results in decreased expression of SESN3 mRNA CTD PMID:20883752 NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:19,415,347...19,466,904 		JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions ISO [Simvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; SGK2 mutant form inhibits the reaction [[Simvastatin co-treated with NR1I2 protein] results in increased secretion of Glucose]; Simvastatin promotes the reaction [NR1I2 protein binds to SGK2 promoter] CTD PMID:24204015 NCBI chr 3:172,063,625...172,089,000
Ensembl chr 3:172,063,776...172,089,011 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Simvastatin results in decreased expression of SLC10A1 mRNA CTD PMID:27765674 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 increases expression ISO Simvastatin results in increased expression of SLC38A4 mRNA CTD PMID:19262002 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:130,023,980...130,082,097 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases activity ISO Simvastatin results in increased activity of SLC6A4 protein CTD PMID:15740995 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP Simvastatin results in decreased expression of SLCO1A1 mRNA CTD PMID:27765674 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Smad1 SMAD family member 1 multiple interactions
increases phosphorylation
increases expression 		ISO Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD1 protein]]
Simvastatin results in increased phosphorylation of SMAD1 protein
Simvastatin results in increased expression of SMAD1 mRNA 		CTD PMID:18310456 PMID:20417880 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957 		JBrowse link
G Smad2 SMAD family member 2 decreases phosphorylation
multiple interactions
increases phosphorylation
increases expression 		EXP
ISO 		Simvastatin results in decreased phosphorylation of SMAD2 protein
FST protein inhibits the reaction [Simvastatin results in increased phosphorylation of SMAD2 protein]
Simvastatin results in increased expression of SMAD2 mRNA 		CTD PMID:18310456 PMID:19659652 PMID:33034787 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad3 SMAD family member 3 increases expression
multiple interactions
increases phosphorylation
decreases phosphorylation 		ISO
EXP 		Simvastatin results in increased expression of SMAD3 mRNA
FST protein inhibits the reaction [Simvastatin results in increased phosphorylation of SMAD3 protein]
Simvastatin results in decreased phosphorylation of SMAD3 protein 		CTD PMID:18310456 PMID:19659652 PMID:33034787 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Smad5 SMAD family member 5 multiple interactions ISO Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD5 protein]] CTD PMID:18310456 NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992 		JBrowse link
G Smad9 SMAD family member 9 multiple interactions ISO Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD9 protein]] CTD PMID:18310456 NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:141,106,668...141,156,477 		JBrowse link
G Snx17 sorting nexin 17 decreases expression
multiple interactions 		EXP Simvastatin results in decreased expression of SNX17 mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SNX17 mRNA 		CTD PMID:25055962 NCBI chr 6:30,897,500...30,902,972
Ensembl chr 6:30,897,501...30,902,972 		JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression EXP Simvastatin results in increased expression of SOAT1 mRNA CTD PMID:12056585 NCBI chr13:71,105,178...71,147,776
Ensembl chr13:71,105,178...71,147,672 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO Simvastatin results in increased expression of SOCS3 mRNA CTD PMID:18453621 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 increases expression ISO Simvastatin results in increased expression of SOCS4 mRNA; Simvastatin results in increased expression of SOCS4 protein CTD PMID:19262002 NCBI chr15:23,003,130...23,017,615
Ensembl chr15:23,002,883...23,022,499 		JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression ISO Simvastatin results in increased expression of SOCS7 mRNA CTD PMID:18453621 NCBI chr10:82,848,525...82,885,201
Ensembl chr10:82,848,612...82,885,201 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO
EXP 		Simvastatin results in decreased expression of SOD2 mRNA CTD PMID:16414398 PMID:20883752 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP Simvastatin inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD3 mRNA] CTD PMID:28734741 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125 		JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO Simvastatin inhibits the reaction [SP1 binds to COL1A1 promoter] CTD PMID:16575855 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Sp7 Sp7 transcription factor multiple interactions
increases expression 		ISO CTNNB1 mutant form inhibits the reaction [Simvastatin results in increased expression of SP7 protein]; DKK1 inhibits the reaction [Simvastatin results in increased expression of SP7 mRNA]
Simvastatin results in increased expression of SP7; Simvastatin results in increased expression of SP7 mRNA; Simvastatin results in increased expression of SP7 protein 		CTD PMID:20564244 PMID:22058016 NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559 		JBrowse link
G Spon2 spondin 2 increases expression ISO Simvastatin results in increased expression of SPON2 mRNA CTD PMID:17428261 NCBI chr14:81,713,070...81,742,510
Ensembl chr14:81,731,188...81,742,609 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression
increases expression 		ISO
EXP 		Simvastatin results in decreased expression of SPP1 mRNA
Simvastatin results in increased expression of SPP1 protein 		CTD PMID:12914771 PMID:14601315 PMID:21076490 PMID:21109955 PMID:22058016 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein; Chloroquine inhibits the reaction [[Simvastatin co-treated with Metformin] results in decreased expression of SQSTM1 protein] CTD PMID:25412314 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases localization
multiple interactions
decreases expression 		ISO
EXP 		Simvastatin results in increased localization of SREBF1 protein
Simvastatin inhibits the reaction [osteum results in increased expression of SREBF1 mRNA]
Simvastatin results in decreased expression of SREBF1 mRNA 		CTD PMID:17655842 PMID:25055962 PMID:33596472 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]]; Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]
Simvastatin results in increased expression of SREBF2 mRNA
Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of SREBF2 mRNA]; Simvastatin results in increased activity of and results in increased localization of SREBF2 protein
Simvastatin results in increased expression of SREBF2 protein modified form 		CTD PMID:12056585 PMID:14500290 PMID:20018177 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions 		EXP Simvastatin results in increased expression of STAR mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of STAR mRNA 		CTD PMID:24524197 PMID:25055962 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
decreases activity
decreases expression
decreases phosphorylation 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT1 protein]; Simvastatin inhibits the reaction [IFNG results in increased expression of STAT1 mRNA]
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT1 protein]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT1 protein]
Simvastatin results in decreased activity of STAT1 protein
Simvastatin results in decreased expression of STAT1 mRNA; Simvastatin results in decreased expression of STAT1 protein
geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 mRNA]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of STAT1 protein]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of STAT1 mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of STAT1 protein]; Simvastatin inhibits the reaction [IFNG promotes the reaction [STAT1 binds to CD40 promoter]]; Simvastatin inhibits the reaction [IFNG results in increased phosphorylation of STAT1 protein] 		CTD PMID:16534557 PMID:17507688 PMID:18453621 PMID:19886038 PMID:21268089 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases activity
decreases phosphorylation
multiple interactions
affects expression 		ISO
EXP 		Simvastatin results in decreased activity of STAT3 protein
Simvastatin results in decreased phosphorylation of STAT3 protein
Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein modified form]; Simvastatin inhibits the reaction [CTF1 results in increased expression of STAT3 protein]; Simvastatin inhibits the reaction [CTF1 results in increased phosphorylation of STAT3 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]
Simvastatin affects the expression of STAT3 protein
Mevalonic Acid inhibits the reaction [Simvastatin results in decreased phosphorylation of STAT3 protein] 		CTD PMID:16534557 PMID:17507688 PMID:18400235 PMID:18453621 PMID:19100119 More... NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A affects expression ISO Simvastatin affects the expression of STAT5A protein CTD PMID:17507688 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 affects expression ISO Simvastatin affects the expression of STAT6 protein CTD PMID:17507688 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO Simvastatin results in increased phosphorylation of STK11 protein CTD PMID:19332549 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 multiple interactions ISO Simvastatin results in decreased activity of [MAP3K7 protein co-treated with TAB1 protein] CTD PMID:17277159 NCBI chr 7:113,556,157...113,587,351
Ensembl chr 7:113,555,819...113,587,351 		JBrowse link
G Tank TRAF family member-associated NFKB activator multiple interactions ISO [Lipopolysaccharides co-treated with Simvastatin] results in increased expression of TANK mRNA CTD PMID:15665042 NCBI chr 3:66,522,834...66,598,864
Ensembl chr 3:66,537,175...66,598,864 		JBrowse link
G Tbxas1 thromboxane A synthase 1 decreases expression
increases expression 		EXP Simvastatin results in decreased expression of TBXAS1 mRNA
Simvastatin results in increased expression of TBXAS1 mRNA 		CTD PMID:16414398 PMID:20659230 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969 		JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions
increases expression 		EXP Simvastatin inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]; Simvastatin results in increased expression of and results in increased activity of TEK protein
Simvastatin results in increased expression of TEK; Simvastatin results in increased expression of TEK mRNA 		CTD PMID:18544044 PMID:20821229 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tf transferrin multiple interactions ISO Simvastatin inhibits the reaction [TNF results in increased expression of TF] CTD PMID:12753293 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400 		JBrowse link
G Tfrc transferrin receptor affects expression ISO Simvastatin affects the expression of TFRC protein CTD PMID:16387846 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
increases activity
increases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]]; Simvastatin inhibits the reaction [TGFB1 results in increased expression of ACTA2 mRNA]; Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 protein]
Simvastatin results in decreased expression of TGFB1 mRNA; Simvastatin results in decreased expression of TGFB1 protein
Simvastatin results in increased activity of TGFB1 protein
Simvastatin results in increased expression of TGFB1 mRNA
Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] 		CTD PMID:15298857 PMID:15677772 PMID:15855201 PMID:16320597 PMID:19080365 More... NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions
decreases expression 		ISO
EXP 		Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of TGFBR2 mRNA]
Simvastatin results in decreased expression of TGFBR2 mRNA 		CTD PMID:16320597 PMID:16373842 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Thbd thrombomodulin increases expression
multiple interactions 		ISO Simvastatin results in increased expression of THBD mRNA; Simvastatin results in increased expression of THBD protein
Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of THBD mRNA] 		CTD PMID:14630613 PMID:16375908 PMID:20493886 PMID:20737288 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Thbs1 thrombospondin 1 decreases expression ISO Simvastatin results in decreased expression of THBS1 mRNA CTD PMID:17428261 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
decreases expression 		EXP Losartan inhibits the reaction [Simvastatin results in decreased expression of TIMP1 mRNA]; Simvastatin inhibits the reaction [Losartan results in decreased expression of TIMP1 mRNA]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of TIMP1 mRNA] CTD PMID:16414398 PMID:20137537 PMID:22022327 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions
decreases expression 		EXP Losartan inhibits the reaction [Simvastatin results in decreased expression of TIMP2 mRNA]; Simvastatin inhibits the reaction [Losartan results in decreased expression of TIMP2 mRNA] CTD PMID:20137537 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression
multiple interactions 		ISO Simvastatin results in increased expression of TLR2 protein
Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] 		CTD PMID:16387846 PMID:16443229 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tlr4 toll-like receptor 4 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Simvastatin results in increased expression of TLR4 protein
Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
Simvastatin results in decreased expression of TLR4 mRNA; Simvastatin results in decreased expression of TLR4 protein 		CTD PMID:16387846 PMID:16443229 PMID:19166837 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Simvastatin results in increased expression of TM7SF2 mRNA CTD PMID:25055962 NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557 		JBrowse link
G Tnc tenascin C decreases expression EXP Simvastatin results in decreased expression of TNC mRNA CTD PMID:16414398 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects secretion
decreases secretion
decreases expression
increases expression
increases secretion
decreases activity 		ISO
EXP 		geranylgeraniol inhibits the reaction [Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCL4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CCR4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of VCAM1 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]]; Simvastatin inhibits the reaction [CCN1 results in increased expression of TNF]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Simvastatin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Simvastatin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BCL2L1 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC3 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of BIRC5 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of CFLAR protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Simvastatin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of VEGFA protein]; Simvastatin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]; Simvastatin inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF results in decreased expression of PLAT]; Simvastatin inhibits the reaction [TNF results in increased activity of RHOA protein]; Simvastatin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of CCR4 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of ICAM1]; Simvastatin inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of ITGAL]; Simvastatin inhibits the reaction [TNF results in increased expression of ITGB2]; Simvastatin inhibits the reaction [TNF results in increased expression of PTGS2 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of PTGS2 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of TF]; Simvastatin inhibits the reaction [TNF results in increased expression of VCAM1 mRNA]; Simvastatin inhibits the reaction [TNF results in increased localization of IL1B protein]; Simvastatin inhibits the reaction [TNF results in increased localization of IL6 protein]; Simvastatin inhibits the reaction [TNF results in increased localization of RELA protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of CCL2 protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of CCL4 mRNA]; Simvastatin inhibits the reaction [TNF results in increased secretion of CXCL8 protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of IL1B protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of IL6 protein]; Simvastatin inhibits the reaction [TNF results in increased secretion of MMP9 protein]; Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Simvastatin promotes the reaction [TNF protein results in increased expression of SELE protein]; Simvastatin promotes the reaction [TNF results in increased expression of MMP9 mRNA]; Simvastatin promotes the reaction [TNF results in increased expression of PPARA]
Simvastatin affects the secretion of TNF protein
Simvastatin results in decreased secretion of TNF protein
Simvastatin results in decreased expression of TNF mRNA; Simvastatin results in decreased expression of TNF protein
Simvastatin results in increased expression of TNF mRNA
Simvastatin results in increased secretion of TNF protein
farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]]; farnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]; Guanidines inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of NOS2 mRNA]]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Simvastatin inhibits the reaction [TNF affects the localization of RHOA protein]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD1 protein]]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD5 protein]]; Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD9 protein]]; Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]; Simvastatin inhibits the reaction [TNF results in increased expression of CXCL15 mRNA]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK1 protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK3 protein]; Simvastatin inhibits the reaction [TNF results in increased phosphorylation of MAPK8 protein]; Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased abundance of Nitric Oxide]; Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of IL6 protein]; Simvastatin promotes the reaction [[Lipopolysaccharides co-treated with TNF] results in increased expression of NOS2 mRNA]; zinc protoporphyrin inhibits the reaction [Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Simvastatin results in decreased activity of TNF; Simvastatin results in decreased activity of TNF protein
1-propyl-8-(4-sulfophenyl)xanthine inhibits the reaction [Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; [Lipopolysaccharides co-treated with Simvastatin] results in increased expression of and results in increased secretion of TNF protein; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased secretion of TNF protein]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in decreased expression of NOS2 protein]]; Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]]; Simvastatin inhibits the reaction [Acetic Acid results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Acrolein results in increased secretion of TNF protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Simvastatin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Simvastatin inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; Simvastatin inhibits the reaction [TNF results in decreased expression of NOS2 protein]; Simvastatin inhibits the reaction [TNF results in increased expression of NOS2 mRNA] 		CTD PMID:10946302 PMID:12117737 PMID:12615677 PMID:12753293 PMID:12829860 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO Simvastatin results in increased expression of TNFRSF11B mRNA CTD PMID:21431270 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Simvastatin results in decreased expression of TNFRSF1A mRNA CTD PMID:18310456 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO Simvastatin results in decreased expression of TNFRSF1B mRNA CTD PMID:18310456 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 multiple interactions
decreases expression 		ISO Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 protein]]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 protein]
Simvastatin results in decreased expression of TNFRSF4 mRNA; Simvastatin results in decreased expression of TNFRSF4 protein 		CTD PMID:19589242 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:171,889,117...171,892,616 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases response to substance 		ISO [Simvastatin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]; Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Mevalonic Acid inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]; Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]
TNFSF10 protein results in increased susceptibility to Simvastatin 		CTD PMID:21910007 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnfsf4 TNF superfamily member 4 multiple interactions
decreases expression 		ISO Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 protein]]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 mRNA]; Simvastatin inhibits the reaction [IFNG results in increased expression of TNFSF4 protein]
Simvastatin results in decreased expression of TNFSF4 mRNA; Simvastatin results in decreased expression of TNFSF4 protein 		CTD PMID:19589242 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP Nitroarginine inhibits the reaction [Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein]]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNNI3 protein] CTD PMID:35762198 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
increases phosphorylation 		ISO
EXP 		pifithrin inhibits the reaction [Simvastatin results in increased expression of TP53 protein]; Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]]; Simvastatin promotes the reaction [TP53 protein binds to CD44 promoter]; Simvastatin results in increased expression of and results in increased phosphorylation of TP53 protein
Simvastatin results in increased expression of TP53 mRNA; Simvastatin results in increased expression of TP53 mutant form; Simvastatin results in increased expression of TP53 protein
Simvastatin results in increased phosphorylation of TP53 protein 		CTD PMID:15625077 PMID:18804536 PMID:20045437 PMID:21199873 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 decreases expression EXP Simvastatin results in decreased expression of TPT1 protein CTD PMID:20217863 NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554 		JBrowse link
G Tradd TNFRSF1A-associated via death domain decreases expression ISO Simvastatin results in decreased expression of TRADD mRNA CTD PMID:17277159 NCBI chr19:50,046,057...50,048,158
Ensembl chr19:50,046,061...50,052,550 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression ISO Simvastatin results in decreased expression of TRAF2 mRNA CTD PMID:17277159 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
G Trim63 tripartite motif containing 63 increases expression
multiple interactions 		EXP
ISO 		Simvastatin results in increased expression of TRIM63 mRNA
Simvastatin results in increased expression of TRIM63 mRNA; Simvastatin results in increased expression of TRIM63 protein
FST protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 mRNA]; FST protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 protein]; IGF1 protein inhibits the reaction [Simvastatin results in increased expression of TRIM63 mRNA] 		CTD PMID:19001041 PMID:27734117 PMID:33034787 NCBI chr 5:151,817,209...151,831,026
Ensembl chr 5:151,817,225...151,831,058 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression EXP Simvastatin results in decreased expression of TXNRD1 mRNA CTD PMID:16414398 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tyms thymidylate synthetase decreases expression ISO Simvastatin results in decreased expression of TYMS mRNA; Simvastatin results in decreased expression of TYMS protein CTD PMID:17428261 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases phosphorylation ISO Simvastatin results in decreased phosphorylation of VASP protein CTD PMID:19332549 NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:88,038,037...88,058,650 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression 		ISO
EXP 		Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [CD40LG results in increased expression of VCAM1 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [TNF results in increased expression of VCAM1 mRNA]]; Simvastatin inhibits the reaction [CD40LG results in increased expression of VCAM1 mRNA]; Simvastatin inhibits the reaction [TNF results in increased expression of VCAM1 mRNA]; Simvastatin promotes the reaction [[Ethinyl Estradiol co-treated with Desogestrel] results in decreased expression of VCAM1 protein]; Simvastatin promotes the reaction [ethinyl estradiol-desogestrel combination results in decreased expression of VCAM1 protein]; Simvastatin promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]; Vitamin E inhibits the reaction [Simvastatin results in decreased expression of VCAM1 protein modified form]
Simvastatin results in decreased expression of VCAM1 mRNA; Simvastatin results in decreased expression of VCAM1 protein
Simvastatin results in decreased expression of VCAM1 mRNA; Simvastatin results in decreased expression of VCAM1 protein; Simvastatin results in decreased expression of VCAM1 protein modified form 		CTD PMID:10946302 PMID:14602771 PMID:15234187 PMID:17105841 PMID:17169357 More... NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vcl vinculin affects localization EXP Simvastatin affects the localization of VCL protein CTD PMID:22306966 NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression EXP Simvastatin results in decreased expression of VDAC1 protein CTD PMID:20217863 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Vdr vitamin D receptor increases expression ISO Simvastatin results in increased expression of VDR mRNA CTD PMID:19262002 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
increases secretion
decreases expression 		ISO
EXP 		geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA]; HIF1A mutant form inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA protein]]; Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [IL6 results in increased expression of VEGFA protein]; Simvastatin inhibits the reaction [TNF protein results in increased expression of VEGFA protein]
Simvastatin inhibits the reaction [Dietary Fats results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Dietary Fats results in increased expression of VEGFA protein]; Simvastatin inhibits the reaction [Glucose results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
Simvastatin results in increased expression of VEGFA mRNA; Simvastatin results in increased expression of VEGFA protein
Simvastatin results in increased secretion of VEGFA protein
Simvastatin results in increased expression of VEGFA; Simvastatin results in increased expression of VEGFA mRNA
Simvastatin results in decreased expression of VEGFA protein 		CTD PMID:15572054 PMID:16424782 PMID:17277159 PMID:18316203 PMID:18356691 More... NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vim vimentin decreases expression ISO
EXP 		Simvastatin results in decreased expression of VIM protein CTD PMID:14973129 PMID:15855201 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vwf von Willebrand factor increases expression EXP Simvastatin results in increased expression of VWF mRNA; Simvastatin results in increased expression of VWF protein CTD PMID:19109527 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Wnt4 Wnt family member 4 multiple interactions
increases expression 		EXP Simvastatin inhibits the reaction [Glucose results in decreased expression of WNT4 mRNA]
Simvastatin results in increased expression of WNT4 protein 		CTD PMID:18004065 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
G Wnt5a Wnt family member 5A multiple interactions
increases expression 		EXP Simvastatin inhibits the reaction [Glucose results in decreased expression of WNT5A mRNA]
Simvastatin results in increased expression of WNT5A mRNA; Simvastatin results in increased expression of WNT5A protein 		CTD PMID:18004065 PMID:19968183 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860 		JBrowse link
G Xbp1 X-box binding protein 1 decreases expression EXP Simvastatin results in decreased expression of XBP1 protein CTD PMID:18807172 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Simvastatin results in decreased expression of XIAP mRNA; Simvastatin results in decreased expression of XIAP protein CTD PMID:19262002 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
G Zfp866 zinc finger protein 866 decreases expression EXP Simvastatin results in decreased expression of CXCL5 mRNA CTD PMID:16414398 NCBI chr16:19,687,869...19,710,407
Ensembl chr16:19,702,297...19,709,330 		JBrowse link
Sorbitan monooleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO sorbitan monooleate binds to and results in increased activity of PPARG protein CTD PMID:27131391 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO sorbitan monooleate binds to and results in increased activity of RXRA protein CTD PMID:27131391 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417 		JBrowse link
testosterone enanthate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 affects expression ISO testosterone enanthate affects the expression of ABCA7 mRNA CTD PMID:17440010 NCBI chr 7:10,342,092...10,362,094
Ensembl chr 7:10,342,092...10,361,989 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase affects expression ISO testosterone enanthate affects the expression of ABHD2 mRNA CTD PMID:17440010 NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 affects expression ISO testosterone enanthate affects the expression of ABLIM3 mRNA CTD PMID:17440010 NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710 		JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 affects expression ISO testosterone enanthate affects the expression of ACBD3 mRNA CTD PMID:17440010 NCBI chr13:94,987,643...95,016,356
Ensembl chr13:94,987,541...95,016,355 		JBrowse link
G Acvr2b activin A receptor type 2B affects expression ISO testosterone enanthate affects the expression of ACVR2B mRNA CTD PMID:17440010 NCBI chr 8:128,016,589...128,056,193
Ensembl chr 8:128,016,526...128,048,171 		JBrowse link
G Adam21 ADAM metallopeptidase domain 21 affects expression ISO testosterone enanthate affects the expression of ADAM21 mRNA CTD PMID:17440010 NCBI chr16:43,351,935...43,361,020
Ensembl chr16:43,351,948...43,361,018 		JBrowse link
G Adamtsl3 ADAMTS-like 3 affects expression ISO testosterone enanthate affects the expression of ADAMTSL3 mRNA CTD PMID:17440010 NCBI chr 1:145,698,004...146,006,195
Ensembl chr 1:145,698,004...146,006,195 		JBrowse link
G Adcy10 adenylate cyclase 10 increases expression EXP testosterone enanthate results in increased expression of ADCY10 mRNA CTD PMID:25603467 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:80,284,295...80,366,926 		JBrowse link
G Adcy3 adenylate cyclase 3 affects expression EXP testosterone enanthate affects the expression of ADCY3 mRNA CTD PMID:25603467 NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173 		JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression EXP testosterone enanthate results in decreased expression of ADCY6 mRNA CTD PMID:25603467 NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770 		JBrowse link
G Adcy9 adenylate cyclase 9 affects expression EXP testosterone enanthate affects the expression of ADCY9 mRNA CTD PMID:25603467 NCBI chr10:11,645,373...11,768,462
Ensembl chr10:11,645,282...11,765,792 		JBrowse link
G Adnp2 ADNP homeobox 2 affects expression ISO testosterone enanthate affects the expression of ADNP2 mRNA CTD PMID:17440010 NCBI chr18:75,846,860...75,871,638
Ensembl chr18:75,847,165...75,903,317 		JBrowse link
G Aggf1 angiogenic factor with G patch and FHA domains 1 affects expression ISO testosterone enanthate affects the expression of AGGF1 mRNA CTD PMID:17440010 NCBI chr 2:28,354,073...28,380,794
Ensembl chr 2:28,354,073...28,380,759 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 affects expression ISO testosterone enanthate affects the expression of AGO3 mRNA CTD PMID:17440010 NCBI chr 5:143,913,957...143,998,746
Ensembl chr 5:143,926,501...143,998,737 		JBrowse link
G Akap13 A-kinase anchoring protein 13 affects expression ISO testosterone enanthate affects the expression of AKAP13 mRNA CTD PMID:17440010 NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 affects expression ISO testosterone enanthate affects the expression of AKR1C1 mRNA CTD PMID:17440010 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 affects expression ISO testosterone enanthate affects the expression of AKR1C2 mRNA CTD PMID:17440010 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects expression ISO testosterone enanthate affects the expression of AKR1C3 mRNA CTD PMID:17440010 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions 		ISO
EXP 		testosterone enanthate results in increased phosphorylation of AKT1 protein
cordycepin inhibits the reaction [testosterone enanthate results in increased phosphorylation of AKT1 protein]; Finasteride inhibits the reaction [testosterone enanthate results in increased phosphorylation of AKT1 protein] 		CTD PMID:17440010 PMID:36015278 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 affects expression ISO testosterone enanthate affects the expression of ALDH1A3 mRNA CTD PMID:17440010 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects expression ISO testosterone enanthate affects the expression of ALDH1B1 mRNA CTD PMID:17440010 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Alkbh4 alkB homolog 4, lysine demethylase affects expression ISO testosterone enanthate affects the expression of ALKBH4 mRNA CTD PMID:17440010 NCBI chr12:26,160,643...26,166,560
Ensembl chr12:26,160,643...26,166,560 		JBrowse link
G Amot angiomotin affects expression ISO testosterone enanthate affects the expression of AMOT mRNA CTD PMID:17440010 NCBI chr  X:113,778,990...113,837,846
Ensembl chr  X:113,781,526...113,837,482 		JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 affects expression ISO testosterone enanthate affects the expression of ANAPC5 mRNA CTD PMID:17440010 NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762 		JBrowse link
G Angpt1 angiopoietin 1 affects expression ISO testosterone enanthate affects the expression of ANGPT1 mRNA CTD PMID:17440010 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Ank1 ankyrin 1 affects expression ISO testosterone enanthate affects the expression of ANK1 mRNA CTD PMID:17440010 NCBI chr16:75,578,824...75,757,464
Ensembl chr16:75,578,824...75,757,464 		JBrowse link
G Ank3 ankyrin 3 affects expression ISO testosterone enanthate affects the expression of ANK3 mRNA CTD PMID:17440010 NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879 		JBrowse link
G Ankrd2 ankyrin repeat domain 2 affects expression ISO testosterone enanthate affects the expression of ANKRD2 mRNA CTD PMID:17440010 NCBI chr 1:250,796,419...250,805,867
Ensembl chr 1:250,796,409...250,805,870 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression ISO testosterone enanthate affects the expression of AP2B1 mRNA CTD PMID:17440010 NCBI chr10:68,596,925...68,702,547
Ensembl chr10:68,597,093...68,702,539 		JBrowse link
G Ap4s1 adaptor related protein complex 4 subunit sigma 1 affects expression ISO testosterone enanthate affects the expression of AP4S1 mRNA CTD PMID:17440010 NCBI chr 6:74,863,742...74,916,907
Ensembl chr 6:74,868,558...74,912,406 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of APOE mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of APOE mRNA CTD PMID:18160741 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G App amyloid beta precursor protein affects expression ISO testosterone enanthate affects the expression of APP mRNA CTD PMID:17440010 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Ar androgen receptor increases activity
increases expression
decreases expression 		ISO
EXP 		testosterone enanthate results in increased activity of AR protein
testosterone enanthate results in increased expression of AR mRNA; testosterone enanthate results in increased expression of AR protein
testosterone enanthate results in decreased expression of AR mRNA; testosterone enanthate results in decreased expression of AR protein 		CTD PMID:17440010 PMID:21427060 PMID:21729141 PMID:23085480 PMID:23294483 More... NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Areg amphiregulin affects expression ISO testosterone enanthate affects the expression of AREG mRNA CTD PMID:17440010 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Armcx3 armadillo repeat containing, X-linked 3 affects expression ISO testosterone enanthate affects the expression of ARMCX3 mRNA CTD PMID:17440010 NCBI chr  X:102,230,464...102,234,017
Ensembl chr  X:102,219,848...102,263,297 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B affects expression ISO testosterone enanthate affects the expression of ARPC1B mRNA CTD PMID:17440010 NCBI chr12:14,595,939...14,609,501
Ensembl chr12:14,595,678...14,609,504 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 affects expression ISO testosterone enanthate affects the expression of DDEFL1 mRNA CTD PMID:17440010 NCBI chr 5:153,716,988...153,757,787
Ensembl chr 5:153,716,988...153,757,787 		JBrowse link
G Asb13 ankyrin repeat and SOCS box-containing 13 affects expression ISO testosterone enanthate affects the expression of ASB13 mRNA CTD PMID:17440010 NCBI chr17:71,474,531...71,493,238
Ensembl chr17:71,474,531...71,505,633 		JBrowse link
G Aspn asporin affects expression ISO testosterone enanthate affects the expression of ASPN mRNA CTD PMID:17440010 NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,287,065...15,310,632 		JBrowse link
G Ass1 argininosuccinate synthase 1 affects expression ISO testosterone enanthate affects the expression of ASS1 mRNA CTD PMID:17440010 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627 		JBrowse link
G Astn2 astrotactin 2 affects expression ISO testosterone enanthate affects the expression of ASTN2 mRNA CTD PMID:17440010 NCBI chr 5:83,772,988...84,759,439
Ensembl chr 5:83,773,633...84,759,485 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 affects expression ISO testosterone enanthate affects the expression of ATP2B1 mRNA CTD PMID:17440010 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression ISO testosterone enanthate affects the expression of ATP6V1A mRNA CTD PMID:17440010 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 affects expression ISO testosterone enanthate affects the expression of ATP8B1 mRNA CTD PMID:17440010 NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027 		JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO testosterone enanthate results in increased expression of ATRX mRNA CTD PMID:17440010 NCBI chr  X:74,916,548...75,062,880
Ensembl chr  X:74,916,548...75,062,880 		JBrowse link
G B4galt4 beta-1,4-galactosyltransferase 4 affects expression ISO testosterone enanthate affects the expression of B4GALT4 mRNA CTD PMID:17440010 NCBI chr11:75,501,358...75,527,291
Ensembl chr11:75,501,366...75,527,177 		JBrowse link
G Bag5 BAG cochaperone 5 affects expression ISO testosterone enanthate affects the expression of BAG5 mRNA CTD PMID:17440010 NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:136,584,741...136,598,492 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in decreased expression of BAX protein]; Finasteride inhibits the reaction [testosterone enanthate results in decreased expression of BAX mRNA]; Finasteride inhibits the reaction [testosterone enanthate results in decreased expression of BAX protein]
testosterone enanthate results in decreased expression of BAX mRNA; testosterone enanthate results in decreased expression of BAX protein 		CTD PMID:30154949 PMID:36015278 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A affects expression ISO testosterone enanthate affects the expression of BAZ1A mRNA CTD PMID:17440010 NCBI chr 6:78,124,872...78,247,672
Ensembl chr 6:78,124,872...78,247,648 		JBrowse link
G Bbx BBX high mobility group box domain containing affects expression ISO testosterone enanthate affects the expression of BBX mRNA CTD PMID:17440010 NCBI chr11:63,850,034...64,097,700
Ensembl chr11:63,850,018...64,093,265 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions 		EXP testosterone enanthate results in increased expression of BCL2 mRNA; testosterone enanthate results in increased expression of BCL2 protein
2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of BCL2 mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in increased expression of BCL2 mRNA]; cordycepin inhibits the reaction [testosterone enanthate results in increased expression of BCL2 protein]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of BCL2 mRNA]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of BCL2 protein] 		CTD PMID:30154949 PMID:36015278 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 affects expression ISO testosterone enanthate affects the expression of BCLAF1 mRNA CTD PMID:17440010 NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801 		JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 affects expression ISO testosterone enanthate affects the expression of BCORL1 mRNA CTD PMID:17440010 NCBI chr  X:132,394,703...132,462,414
Ensembl chr  X:132,397,069...132,461,976 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 affects expression ISO testosterone enanthate affects the expression of BHMT2 mRNA CTD PMID:17440010 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326 		JBrowse link
G Bltp2 bridge-like lipid transfer protein family member 2 affects expression ISO testosterone enanthate affects the expression of BLTP2 mRNA CTD PMID:17440010 NCBI chr10:63,654,072...63,683,282
Ensembl chr10:63,654,104...63,683,282 		JBrowse link
G Bmp2k BMP-2 inducible kinase affects expression ISO testosterone enanthate affects the expression of BMP2K mRNA CTD PMID:17440010 NCBI chr14:12,785,169...12,882,676
Ensembl chr14:12,785,169...12,882,657 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects expression ISO testosterone enanthate affects the expression of BNIP3L mRNA CTD PMID:17440010 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Bptf bromodomain PHD finger transcription factor affects expression ISO testosterone enanthate affects the expression of BPTF mRNA CTD PMID:17440010 NCBI chr10:92,480,007...92,582,485
Ensembl chr10:92,480,007...92,582,413 		JBrowse link
G Brd2 bromodomain containing 2 affects expression ISO testosterone enanthate affects the expression of BRD2 mRNA CTD PMID:17440010 NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290 		JBrowse link
G Btd biotinidase affects expression ISO testosterone enanthate affects the expression of BTD mRNA CTD PMID:17440010 NCBI chr16:6,869,448...6,900,711
Ensembl chr16:6,869,291...6,901,410 		JBrowse link
G C1qa complement C1q A chain affects expression ISO testosterone enanthate affects the expression of C1QA mRNA CTD PMID:17440010 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732 		JBrowse link
G C2h1orf54 similar to human chromosome 1 open reading frame 54 affects expression ISO testosterone enanthate affects the expression of C1ORF54 mRNA CTD PMID:17440010 NCBI chr 2:186,113,922...186,124,637
Ensembl chr 2:186,113,922...186,124,335 		JBrowse link
G Camkmt calmodulin-lysine N-methyltransferase affects expression ISO testosterone enanthate affects the expression of CAMKMT mRNA CTD PMID:17440010 NCBI chr 6:14,951,838...15,332,966
Ensembl chr 6:14,951,840...15,333,106 		JBrowse link
G Camsap2 calmodulin regulated spectrin-associated protein family, member 2 affects expression ISO testosterone enanthate affects the expression of CAMSAP2 mRNA CTD PMID:17440010 NCBI chr13:50,274,950...50,354,298
Ensembl chr13:50,274,950...50,354,298 		JBrowse link
G Capn2 calpain 2 affects expression ISO testosterone enanthate affects the expression of CAPN2 mRNA CTD PMID:17440010 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Capn6 calpain 6 affects expression ISO testosterone enanthate affects the expression of CAPN6 mRNA CTD PMID:17440010 NCBI chr  X:112,177,467...112,202,178
Ensembl chr  X:112,177,467...112,202,178 		JBrowse link
G Casp6 caspase 6 affects expression ISO testosterone enanthate affects the expression of CASP6 mRNA CTD PMID:17440010 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Cavin1 caveolae associated protein 1 affects expression ISO testosterone enanthate affects the expression of CAVIN1 mRNA CTD PMID:17440010 NCBI chr10:86,384,401...86,398,240
Ensembl chr10:86,384,401...86,396,383 		JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO testosterone enanthate affects the expression of CBR1 mRNA CTD PMID:17440010 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104 		JBrowse link
G Cbx5 chromobox 5 affects expression ISO testosterone enanthate affects the expression of CBX5 mRNA CTD PMID:17440010 NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118 		JBrowse link
G Ccdc85b coiled-coil domain containing 85B affects expression ISO testosterone enanthate affects the expression of CCDC85B mRNA CTD PMID:17440010 NCBI chr 1:212,192,979...212,193,994
Ensembl chr 1:212,189,468...212,196,911 		JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 affects expression ISO testosterone enanthate affects the expression of CCHCR1 mRNA CTD PMID:17440010 NCBI chr20:3,210,383...3,223,187
Ensembl chr20:3,210,384...3,222,765 		JBrowse link
G Ccn5 cellular communication network factor 5 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CCN5 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CCN5 mRNA CTD PMID:18160741 NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression 		EXP cordycepin inhibits the reaction [testosterone enanthate results in increased expression of CCND1 protein]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of CCND1 protein] CTD PMID:36015278 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne2 cyclin E2 affects expression ISO testosterone enanthate affects the expression of CCNE2 mRNA CTD PMID:17440010 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Ccpg1 cell cycle progression 1 affects expression ISO testosterone enanthate affects the expression of CPR8 mRNA CTD PMID:17440010 NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 affects expression ISO testosterone enanthate affects the expression of CCR1 mRNA CTD PMID:17440010 NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374 		JBrowse link
G Ccs copper chaperone for superoxide dismutase affects expression ISO testosterone enanthate affects the expression of CCS mRNA CTD PMID:17440010 NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260 		JBrowse link
G Cd151 CD151 molecule (Raph blood group) affects expression ISO testosterone enanthate affects the expression of CD151 mRNA CTD PMID:17440010 NCBI chr 1:205,994,300...205,998,307
Ensembl chr 1:205,994,738...205,998,784 		JBrowse link
G Cd53 Cd53 molecule affects expression ISO testosterone enanthate affects the expression of CD53 mRNA CTD PMID:17440010 NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:197,040,369...197,218,593 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression ISO testosterone enanthate affects the expression of CDK1 mRNA CTD PMID:17440010 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 affects expression ISO testosterone enanthate affects the expression of CDKAL1 mRNA CTD PMID:17440010 NCBI chr17:34,927,221...35,479,827
Ensembl chr17:34,950,157...35,479,905 		JBrowse link
G Cep104 centrosomal protein 104 affects expression ISO testosterone enanthate affects the expression of CEP104 mRNA CTD PMID:17440010 NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695 		JBrowse link
G Cep57 centrosomal protein 57 affects expression ISO testosterone enanthate affects the expression of CEP57 mRNA CTD PMID:17440010 NCBI chr 8:18,951,179...18,971,205
Ensembl chr 8:18,932,808...18,970,890 		JBrowse link
G Ces2h carboxylesterase 2H affects expression ISO testosterone enanthate affects the expression of CES2 mRNA CTD PMID:17440010 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752 		JBrowse link
G Cfh complement factor H affects expression ISO testosterone enanthate affects the expression of CFH mRNA CTD PMID:17440010 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide decreases expression EXP testosterone enanthate results in decreased expression of CGA mRNA CTD PMID:25603467 NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 affects expression ISO testosterone enanthate affects the expression of CHD4 mRNA CTD PMID:17440010 NCBI chr 4:159,584,623...159,617,867
Ensembl chr 4:159,584,654...159,617,866 		JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 affects expression ISO testosterone enanthate affects the expression of CHD8 mRNA CTD PMID:17440010 NCBI chr15:27,379,285...27,438,959
Ensembl chr15:27,379,285...27,417,851 		JBrowse link
G Chga chromogranin A multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CHGA mRNA CTD PMID:18160741 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 affects expression ISO testosterone enanthate affects the expression of CKAP2 mRNA CTD PMID:17440010 NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 affects expression ISO testosterone enanthate affects the expression of CKS2 mRNA CTD PMID:17440010 NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 affects expression ISO testosterone enanthate affects the expression of CLCN3 mRNA CTD PMID:17440010 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Clic4 chloride intracellular channel 4 affects expression ISO testosterone enanthate affects the expression of CLIC4 mRNA CTD PMID:17440010 NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118 		JBrowse link
G Cluap1 clusterin associated protein 1 affects expression ISO testosterone enanthate affects the expression of CLUAP1 mRNA CTD PMID:17440010 NCBI chr10:12,094,346...12,159,440
Ensembl chr10:12,094,346...12,131,693 		JBrowse link
G Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A increases expression EXP testosterone enanthate results in increased expression of CMTM2A mRNA CTD PMID:25603467 NCBI chr19:678,154...685,274
Ensembl chr19:678,135...685,390 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 affects expression ISO testosterone enanthate affects the expression of CNOT3 mRNA CTD PMID:17440010 NCBI chr 1:74,471,284...74,487,527
Ensembl chr 1:74,470,566...74,487,527 		JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 affects expression ISO testosterone enanthate affects the expression of CNOT4 mRNA CTD PMID:17440010 NCBI chr 4:64,679,903...64,781,432
Ensembl chr 4:64,679,904...64,738,083 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain affects expression ISO testosterone enanthate affects the expression of COL14A1 mRNA CTD PMID:17440010 NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938 		JBrowse link
G Col1a1 collagen type I alpha 1 chain affects expression ISO testosterone enanthate affects the expression of COL1A1 mRNA CTD PMID:17440010 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col1a2 collagen type I alpha 2 chain affects expression ISO testosterone enanthate affects the expression of COL1A2 mRNA CTD PMID:17440010 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col3a1 collagen type III alpha 1 chain affects expression ISO testosterone enanthate affects the expression of COL3A1 mRNA CTD PMID:17440010 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain affects expression ISO testosterone enanthate affects the expression of COL4A2 mRNA CTD PMID:17440010 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520 		JBrowse link
G Col5a1 collagen type V alpha 1 chain affects expression ISO testosterone enanthate affects the expression of COL5A1 mRNA CTD PMID:17440010 NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020 		JBrowse link
G Col5a2 collagen type V alpha 2 chain affects expression ISO testosterone enanthate affects the expression of COL5A2 mRNA CTD PMID:17440010 NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain affects expression ISO testosterone enanthate affects the expression of COL6A1 mRNA CTD PMID:17440010 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain affects expression ISO testosterone enanthate affects the expression of COL6A2 mRNA CTD PMID:17440010 NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042 		JBrowse link
G Cpne3 copine 3 affects expression ISO testosterone enanthate affects the expression of CPNE3 mRNA CTD PMID:17440010 NCBI chr 5:37,811,566...37,860,840
Ensembl chr 5:37,811,566...37,861,062 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression EXP testosterone enanthate results in decreased expression of CREB1 mRNA CTD PMID:25603467 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 affects expression ISO testosterone enanthate affects the expression of CRIM1 mRNA CTD PMID:17440010 NCBI chr 6:22,447,983...22,622,459
Ensembl chr 6:22,449,948...22,622,416 		JBrowse link
G Cst9l cystatin 9-like multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in increased expression of CST9L mRNA; [cetrorelix co-treated with testosterone enanthate] results in increased expression of CST9L mRNA CTD PMID:18160741 NCBI chr 3:156,741,232...156,744,045
Ensembl chr 3:156,741,232...156,744,045 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 affects expression ISO testosterone enanthate affects the expression of CTDP1 mRNA CTD PMID:17440010 NCBI chr18:76,129,243...76,193,404
Ensembl chr18:76,129,243...76,190,578 		JBrowse link
G Ctss cathepsin S affects expression ISO testosterone enanthate affects the expression of CTSS mRNA CTD PMID:17440010 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cul5 cullin 5 affects expression ISO testosterone enanthate affects the expression of CUL5 mRNA CTD PMID:17440010 NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:62,912,193...62,965,463 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYB5A mRNA CTD PMID:18160741 NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094 		JBrowse link
G Cyba cytochrome b-245 alpha chain affects expression ISO testosterone enanthate affects the expression of CYBA mRNA CTD PMID:17440010 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions 		EXP
ISO 		testosterone enanthate results in decreased expression of CYP11A1 mRNA
[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP11A1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYP11A1 mRNA 		CTD PMID:18160741 PMID:21427060 PMID:25603467 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression 		ISO
EXP 		[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of CYP17A1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of CYP17A1 mRNA
testosterone enanthate results in decreased expression of CYP17A1 mRNA 		CTD PMID:18160741 PMID:21427060 PMID:25603467 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression
decreases expression 		EXP testosterone enanthate results in increased expression of CYP19A1 mRNA
testosterone enanthate results in decreased expression of CYP19A1 mRNA 		CTD PMID:21427060 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP testosterone enanthate results in decreased expression of CYP2A1 protein CTD PMID:8573203 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
increases expression 		EXP Tamoxifen promotes the reaction [testosterone enanthate results in increased expression of CYP2C11 protein]
testosterone enanthate results in increased expression of CYP2C11 mRNA; testosterone enanthate results in increased expression of CYP2C11 protein 		CTD PMID:8573203 PMID:8819526 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression 		EXP Tamoxifen promotes the reaction [testosterone enanthate results in increased expression of CYP3A2 protein] CTD PMID:8573203 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cytip cytohesin 1 interacting protein affects expression ISO testosterone enanthate affects the expression of CYTIP mRNA CTD PMID:17440010 NCBI chr 3:63,106,895...63,183,769
Ensembl chr 3:63,107,607...63,134,832 		JBrowse link
G Dab2 DAB adaptor protein 2 affects expression ISO testosterone enanthate affects the expression of DAB2 mRNA CTD PMID:17440010 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in increased expression of DDR1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in increased expression of DDR1 mRNA CTD PMID:18160741 NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276 		JBrowse link
G Ddx17 DEAD-box helicase 17 affects expression ISO testosterone enanthate affects the expression of DDX17 mRNA CTD PMID:17440010 NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747 		JBrowse link
G Ddx24 DEAD-box helicase 24 affects expression ISO testosterone enanthate affects the expression of DDX24 mRNA CTD PMID:17440010 NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625 		JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked affects expression ISO testosterone enanthate affects the expression of DDX3Y mRNA CTD PMID:17440010 NCBI chr  Y:1,190,042...1,210,699
Ensembl chr  Y:1,191,242...1,210,650 		JBrowse link
G Desi2 desumoylating isopeptidase 2 affects expression ISO testosterone enanthate affects the expression of DESI2 mRNA CTD PMID:17440010 NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DHCR24 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of DHCR24 mRNA CTD PMID:18160741 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression ISO testosterone enanthate affects the expression of DHRS4 mRNA CTD PMID:17440010 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101 		JBrowse link
G Dhx29 DExH-box helicase 29 affects expression ISO testosterone enanthate affects the expression of DHX29 mRNA CTD PMID:17440010 NCBI chr 2:46,293,901...46,344,652
Ensembl chr 2:46,293,677...46,344,948 		JBrowse link
G Dhx38 DEAH-box helicase 38 affects expression ISO testosterone enanthate affects the expression of DHX38 mRNA CTD PMID:17440010 NCBI chr19:54,422,418...54,439,434
Ensembl chr19:54,422,418...54,439,423 		JBrowse link
G Diaph2 diaphanous-related formin 2 affects expression ISO testosterone enanthate affects the expression of DIAPH2 mRNA CTD PMID:17440010 NCBI chr  X:96,700,535...97,528,080
Ensembl chr  X:96,700,726...97,528,080 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A affects expression ISO testosterone enanthate affects the expression of DIP2A mRNA CTD PMID:17440010 NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,038...12,370,532 		JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 affects expression ISO testosterone enanthate affects the expression of DKK2 mRNA CTD PMID:17440010 NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724 		JBrowse link
G Dnajb14 DnaJ heat shock protein family (Hsp40) member B14 affects expression ISO testosterone enanthate affects the expression of DNAJB14 mRNA CTD PMID:17440010 NCBI chr 2:229,032,415...229,075,905
Ensembl chr 2:229,032,286...229,075,922 		JBrowse link
G Dnajc4 DnaJ heat shock protein family (Hsp40) member C4 affects expression ISO testosterone enanthate affects the expression of DNAJC4 mRNA CTD PMID:17440010 NCBI chr 1:213,607,397...213,611,614
Ensembl chr 1:213,607,399...213,611,729 		JBrowse link
G Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 affects expression ISO testosterone enanthate affects the expression of DNAJC7 mRNA CTD PMID:17440010 NCBI chr10:86,018,977...86,055,419
Ensembl chr10:86,018,961...86,055,489 		JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 affects expression ISO testosterone enanthate affects the expression of DNPH1 mRNA CTD PMID:17440010 NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631 		JBrowse link
G Dpep3 dipeptidase 3 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DPEP3 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of DPEP3 mRNA CTD PMID:18160741 NCBI chr19:50,778,079...50,786,451
Ensembl chr19:50,777,579...50,783,741 		JBrowse link
G Dpt dermatopontin affects expression ISO testosterone enanthate affects the expression of DPT mRNA CTD PMID:17440010 NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758 		JBrowse link
G Dsn1 DSN1 component of MIS12 kinetochore complex affects expression ISO testosterone enanthate affects the expression of DSN1 mRNA CTD PMID:17440010 NCBI chr 3:166,072,775...166,089,029
Ensembl chr 3:166,074,033...166,085,890 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP testosterone enanthate results in decreased expression of DUSP1 mRNA CTD PMID:23085480 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G E2f3 E2F transcription factor 3 affects expression ISO testosterone enanthate affects the expression of E2F3 mRNA CTD PMID:17440010 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725 		JBrowse link
G Ect2 epithelial cell transforming 2 affects expression ISO testosterone enanthate affects the expression of ECT2 mRNA CTD PMID:17440010 NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626 		JBrowse link
G Ednra endothelin receptor type A affects expression ISO testosterone enanthate affects the expression of EDNRA mRNA CTD PMID:17440010 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B affects expression ISO testosterone enanthate affects the expression of EDNRB mRNA CTD PMID:17440010 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Efemp2 EGF containing fibulin extracellular matrix protein 2 affects expression ISO testosterone enanthate affects the expression of EFEMP2 mRNA CTD PMID:17440010 NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739 		JBrowse link
G Efnb2 ephrin B2 affects expression ISO testosterone enanthate affects the expression of EFNB2 mRNA CTD PMID:17440010 NCBI chr16:87,485,215...87,529,224
Ensembl chr16:87,485,198...87,529,208 		JBrowse link
G Ehbp1l1 EH domain binding protein 1-like 1 affects expression ISO testosterone enanthate affects the expression of EHBP1L1 mRNA CTD PMID:17440010 NCBI chr 1:212,423,444...212,444,357
Ensembl chr 1:212,423,447...212,443,598 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 affects expression ISO testosterone enanthate affects the expression of EIF2AK2 mRNA CTD PMID:17440010 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha affects expression ISO testosterone enanthate affects the expression of EIF2S1 mRNA CTD PMID:17440010 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 affects expression ISO testosterone enanthate affects the expression of EIF4G1 mRNA CTD PMID:17440010 NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367 		JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 affects expression ISO testosterone enanthate affects the expression of EIF4G3 mRNA CTD PMID:17440010 NCBI chr 5:155,481,378...155,702,194
Ensembl chr 5:155,481,378...155,702,194 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B affects expression ISO testosterone enanthate affects the expression of IF2 mRNA CTD PMID:17440010 NCBI chr 9:47,718,706...47,773,289
Ensembl chr 9:47,718,706...47,778,583 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 affects expression ISO testosterone enanthate affects the expression of ELF1 mRNA CTD PMID:17440010 NCBI chr15:61,354,026...61,395,762
Ensembl chr15:61,330,877...61,395,758 		JBrowse link
G Elk1 ETS transcription factor ELK1 affects expression ISO testosterone enanthate affects the expression of ELK1 mRNA CTD PMID:17440010 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Eloa elongin A affects expression ISO testosterone enanthate affects the expression of ELOA mRNA CTD PMID:17440010 NCBI chr 5:153,513,246...153,530,819
Ensembl chr 5:153,515,066...153,530,916 		JBrowse link
G Elp5 elongator acetyltransferase complex subunit 5 affects expression ISO testosterone enanthate affects the expression of ELP5 mRNA CTD PMID:17440010 NCBI chr10:55,191,223...55,202,949
Ensembl chr10:55,191,227...55,203,617 		JBrowse link
G Emc1 ER membrane protein complex subunit 1 affects expression ISO testosterone enanthate affects the expression of EMC1 mRNA CTD PMID:17440010 NCBI chr 5:156,891,773...156,917,092
Ensembl chr 5:156,891,773...156,917,092 		JBrowse link
G Emd emerin affects expression ISO testosterone enanthate affects the expression of EMD mRNA CTD PMID:17440010 NCBI chr  X:157,190,438...157,193,479
Ensembl chr  X:157,189,819...157,197,095 		JBrowse link
G Eng endoglin affects expression ISO testosterone enanthate affects the expression of ENG mRNA CTD PMID:17440010 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression ISO testosterone enanthate affects the expression of ENPP1 mRNA CTD PMID:17440010 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 affects expression ISO testosterone enanthate affects the expression of ENTPD1 mRNA CTD PMID:17440010 NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:249,374,836...249,502,317 		JBrowse link
G Ephb4 EPH receptor B4 affects expression ISO testosterone enanthate affects the expression of EPHB4 mRNA CTD PMID:17440010 NCBI chr12:24,963,174...24,988,473
Ensembl chr12:24,963,174...24,988,388 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 affects expression ISO testosterone enanthate affects the expression of EPRS1 mRNA CTD PMID:17440010 NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509 		JBrowse link
G Erc1 ELKS/RAB6-interacting/CAST family member 1 affects expression ISO testosterone enanthate affects the expression of ERC1 mRNA CTD PMID:17440010 NCBI chr 4:154,435,936...154,727,987
Ensembl chr 4:154,435,944...154,727,987 		JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog affects expression ISO testosterone enanthate affects the expression of ESF1 mRNA CTD PMID:17440010 NCBI chr 3:147,908,405...147,961,567
Ensembl chr 3:147,908,405...147,961,485 		JBrowse link
G Esr1 estrogen receptor 1 increases expression
decreases expression
increases activity 		EXP testosterone enanthate results in increased expression of ESR1 mRNA; testosterone enanthate results in increased expression of ESR1 protein
testosterone enanthate results in decreased expression of ESR1 mRNA
testosterone enanthate results in increased activity of ESR1 protein 		CTD PMID:12504345 PMID:21427060 PMID:21729141 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esrrg estrogen-related receptor gamma affects expression ISO testosterone enanthate affects the expression of ESRRG mRNA CTD PMID:17440010 NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877 		JBrowse link
G Extl1 exostosin-like glycosyltransferase 1 affects expression ISO testosterone enanthate affects the expression of EXTL1 mRNA CTD PMID:17440010 NCBI chr 5:151,857,629...151,872,830
Ensembl chr 5:151,857,629...151,872,830 		JBrowse link
G Ezr ezrin affects expression ISO testosterone enanthate affects the expression of EZR mRNA CTD PMID:17440010 NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573 		JBrowse link
G F2 coagulation factor II, thrombin increases expression ISO testosterone enanthate results in increased expression of F2 protein CTD PMID:8585008 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Faf2 Fas associated factor family member 2 affects expression ISO testosterone enanthate affects the expression of FAF2 mRNA CTD PMID:17440010 NCBI chr17:9,952,329...9,994,596
Ensembl chr17:9,952,329...9,994,711 		JBrowse link
G Fam149a family with sequence similarity 149, member A affects expression ISO testosterone enanthate affects the expression of FAM149A mRNA CTD PMID:17440010 NCBI chr16:53,587,841...53,647,072
Ensembl chr16:53,587,841...53,647,072 		JBrowse link
G Fam162a family with sequence similarity 162, member A affects expression ISO testosterone enanthate affects the expression of FAM162A mRNA CTD PMID:17440010 NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560 		JBrowse link
G Fancc FA complementation group C affects expression ISO testosterone enanthate affects the expression of FANCC mRNA CTD PMID:17440010 NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096 		JBrowse link
G Fastk Fas-activated serine/threonine kinase affects expression ISO testosterone enanthate affects the expression of FASTK mRNA CTD PMID:17440010 NCBI chr 4:11,624,697...11,628,769
Ensembl chr 4:11,624,689...11,629,867 		JBrowse link
G Fbxo40 F-box protein 40 affects expression ISO testosterone enanthate affects the expression of FBXO40 mRNA CTD PMID:17440010 NCBI chr11:77,299,826...77,318,086
Ensembl chr11:77,300,013...77,318,086 		JBrowse link
G Fcer1g Fc epsilon receptor Ig affects expression ISO testosterone enanthate affects the expression of FCER1G mRNA CTD PMID:17440010 NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859 		JBrowse link
G Fcgr2a Fc gamma receptor 2A affects expression ISO testosterone enanthate affects the expression of FCGR2A mRNA CTD PMID:17440010 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects expression ISO testosterone enanthate affects the expression of FERMT2 mRNA CTD PMID:17440010 NCBI chr15:21,162,603...21,257,995
Ensembl chr15:21,162,605...21,258,115 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 affects expression ISO testosterone enanthate affects the expression of FEZ1 mRNA CTD PMID:17440010 NCBI chr 8:44,733,288...44,778,519
Ensembl chr 8:44,733,300...44,784,097 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase affects expression ISO testosterone enanthate affects the expression of FHIT mRNA CTD PMID:17440010 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:16,747,338...17,872,621 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 affects expression ISO testosterone enanthate affects the expression of FKBP4 mRNA CTD PMID:17440010 NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:163,389,464...163,397,918 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 affects expression ISO testosterone enanthate affects the expression of FKBP5 mRNA CTD PMID:17440010 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 affects expression ISO testosterone enanthate affects the expression of FKBP8 mRNA CTD PMID:17440010 NCBI chr16:18,929,581...18,936,621
Ensembl chr16:18,929,582...18,936,543 		JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 affects expression ISO testosterone enanthate affects the expression of FLRT2 mRNA CTD PMID:17440010 NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 affects expression ISO testosterone enanthate affects the expression of FMO2 mRNA CTD PMID:17440010 NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534 		JBrowse link
G Frzb frizzled-related protein affects expression ISO testosterone enanthate affects the expression of FRZB mRNA CTD PMID:17440010 NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:85,739,165...85,772,096 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression 		ISO
EXP 		[FSHB protein co-treated with testosterone enanthate] results in increased abundance of Dihydrotestosterone; [FSHB protein co-treated with testosterone enanthate] results in increased abundance of Estradiol; [FSHB protein co-treated with testosterone enanthate] results in increased abundance of Testosterone
testosterone enanthate results in decreased expression of FSHB protein 		CTD PMID:8263139 PMID:21729141 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Fxr1 FMR1 autosomal homolog 1 affects expression ISO testosterone enanthate affects the expression of FXR1 mRNA CTD PMID:17440010 NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027 		JBrowse link
G Fxr2 FMR1 autosomal homolog 2 affects expression ISO testosterone enanthate affects the expression of FXR2 mRNA CTD PMID:17440010 NCBI chr10:54,849,345...54,869,713
Ensembl chr10:54,849,267...54,869,713 		JBrowse link
G Galk2 galactokinase 2 affects expression ISO testosterone enanthate affects the expression of GALK2 mRNA CTD PMID:17440010 NCBI chr 3:133,563,524...133,696,423
Ensembl chr 3:133,563,538...133,696,528 		JBrowse link
G Gata4 GATA binding protein 4 affects expression EXP testosterone enanthate affects the expression of GATA4 mRNA CTD PMID:25603467 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gbp1 guanylate binding protein 1 affects expression ISO testosterone enanthate affects the expression of GBP1 mRNA CTD PMID:17440010 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802 		JBrowse link
G Gbp2 guanylate binding protein 2 affects expression ISO testosterone enanthate affects the expression of GBP2 mRNA CTD PMID:17440010 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810 		JBrowse link
G Gcat glycine C-acetyltransferase affects expression ISO testosterone enanthate affects the expression of GCAT mRNA CTD PMID:17440010 NCBI chr 7:112,475,572...112,481,920
Ensembl chr 7:112,475,496...112,482,664 		JBrowse link
G Gid4 GID complex subunit 4 affects expression ISO testosterone enanthate affects the expression of GID4 mRNA CTD PMID:17440010 NCBI chr10:45,721,055...45,747,132
Ensembl chr10:45,720,759...45,747,323 		JBrowse link
G Glg1 golgi glycoprotein 1 affects expression ISO testosterone enanthate affects the expression of GLG1 mRNA CTD PMID:17440010 NCBI chr19:56,034,248...56,133,538
Ensembl chr19:56,006,459...56,133,528 		JBrowse link
G Gnb1 G protein subunit beta 1 affects expression ISO testosterone enanthate affects the expression of GNB1 mRNA CTD PMID:17440010 NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488 		JBrowse link
G Gnl3l G protein nucleolar 3 like affects expression ISO testosterone enanthate affects the expression of GNL3L mRNA CTD PMID:17440010 NCBI chr  X:23,404,324...23,437,501
Ensembl chr  X:23,404,324...23,439,315 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor affects expression EXP testosterone enanthate affects the expression of GNRHR mRNA CTD PMID:25603467 NCBI chr14:22,211,666...22,229,654 JBrowse link
G Golga1 golgin A1 affects expression ISO testosterone enanthate affects the expression of GOLGA1 mRNA CTD PMID:17440010 NCBI chr 3:43,175,400...43,222,319
Ensembl chr 3:43,175,400...43,222,319 		JBrowse link
G Golga2 golgin A2 affects expression ISO testosterone enanthate affects the expression of GOLGA2 mRNA CTD PMID:17440010 NCBI chr 3:35,981,783...36,002,023
Ensembl chr 3:35,981,499...36,002,022 		JBrowse link
G Golga4 golgin A4 affects expression ISO testosterone enanthate affects the expression of GOLGA4 mRNA CTD PMID:17440010 NCBI chr 8:127,085,830...127,163,227
Ensembl chr 8:127,085,848...127,163,603 		JBrowse link
G Golim4 golgi integral membrane protein 4 affects expression ISO testosterone enanthate affects the expression of GOLIM4 mRNA CTD PMID:17440010 NCBI chr 2:162,939,429...163,031,901
Ensembl chr 2:162,939,429...163,031,901 		JBrowse link
G Gpatch8 G patch domain containing 8 affects expression ISO testosterone enanthate affects the expression of GPATCH8 mRNA CTD PMID:17440010 NCBI chr10:87,932,174...88,012,523
Ensembl chr10:87,932,174...88,012,523 		JBrowse link
G Gpc1 glypican 1 affects expression ISO testosterone enanthate affects the expression of GPC1 mRNA CTD PMID:17440010 NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933 		JBrowse link
G Gpm6b glycoprotein m6b affects expression ISO testosterone enanthate affects the expression of GPM6B mRNA CTD PMID:17440010 NCBI chr  X:31,689,485...31,836,199
Ensembl chr  X:31,690,359...31,733,272 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects expression ISO testosterone enanthate affects the expression of GPSM2 mRNA CTD PMID:17440010 NCBI chr 2:199,015,250...199,063,788
Ensembl chr 2:199,015,250...199,063,056 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist affects expression ISO testosterone enanthate affects the expression of GREM1 mRNA CTD PMID:17440010 NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression ISO testosterone enanthate affects the expression of GSK3B mRNA CTD PMID:17440010 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of GSTA2 mRNA CTD PMID:18160741 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression ISO testosterone enanthate affects the expression of GSTM1 mRNA CTD PMID:17440010 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gtpbp8 GTP binding protein 8 affects expression ISO testosterone enanthate affects the expression of GTPBP8 mRNA CTD PMID:17440010 NCBI chr11:69,451,776...69,461,744
Ensembl chr11:69,451,795...69,461,743 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha affects expression ISO testosterone enanthate affects the expression of HADHA mRNA CTD PMID:17440010 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 affects expression ISO testosterone enanthate affects the expression of HBG1 mRNA CTD PMID:17440010 NCBI chr 1:167,683,760...167,685,315
Ensembl chr 1:167,683,760...167,706,139 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase affects expression ISO testosterone enanthate affects the expression of HCK mRNA CTD PMID:17440010 NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 affects expression ISO testosterone enanthate affects the expression of HCLS1 mRNA CTD PMID:17440010 NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387 		JBrowse link
G Heph hephaestin affects expression ISO testosterone enanthate affects the expression of HEPH mRNA CTD PMID:17440010 NCBI chr  X:65,160,628...65,412,457
Ensembl chr  X:65,305,773...65,412,453 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase affects expression ISO testosterone enanthate affects the expression of HIBCH mRNA CTD PMID:17440010 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions
increases expression 		EXP testosterone enanthate results in decreased expression of HIF1A mRNA
2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of HIF1A protein] 		CTD PMID:23085480 PMID:30154949 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 affects expression ISO testosterone enanthate affects the expression of HIPK1 mRNA CTD PMID:17440010 NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:193,937,261...193,975,164 		JBrowse link
G Hivep2 HIVEP zinc finger 2 affects expression ISO testosterone enanthate affects the expression of HIVEP2 mRNA CTD PMID:17440010 NCBI chr 1:10,176,880...10,376,089
Ensembl chr 1:10,179,402...10,376,089 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of HMGCS2 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of HMGCS2 mRNA CTD PMID:18160741 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C affects expression ISO testosterone enanthate affects the expression of HNRNPC mRNA CTD PMID:17440010 NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715 		JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R affects expression ISO testosterone enanthate affects the expression of HNRNPR mRNA CTD PMID:17440010 NCBI chr 5:153,826,482...153,872,272
Ensembl chr 5:153,826,692...153,858,344 		JBrowse link
G Hoxa7 homeobox A7 affects expression ISO testosterone enanthate affects the expression of HOXA7 mRNA CTD PMID:17440010 NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241 		JBrowse link
G Hoxb6 homeo box B6 affects expression ISO testosterone enanthate affects the expression of HOXB6 mRNA CTD PMID:17440010 NCBI chr10:81,755,263...81,763,999 JBrowse link
G Hoxb7 homeo box B7 affects expression ISO testosterone enanthate affects the expression of HOXB7 mRNA CTD PMID:17440010 NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,749,097...81,752,550 		JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 affects expression ISO testosterone enanthate affects the expression of HPS1 mRNA CTD PMID:17440010 NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP testosterone enanthate affects the expression of HSD17B4 mRNA CTD PMID:25603467 NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of HSD17B6 mRNA CTD PMID:18160741 NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 increases expression EXP testosterone enanthate results in increased expression of HSD3B5 mRNA CTD PMID:21427060 PMID:25603467 NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 affects expression ISO testosterone enanthate affects the expression of HSP90B1 mRNA CTD PMID:17440010 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression ISO testosterone enanthate affects the expression of HSPA1B mRNA CTD PMID:17440010 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 affects expression ISO testosterone enanthate affects the expression of HSPA4 mRNA CTD PMID:17440010 NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects expression ISO testosterone enanthate affects the expression of HTATIP2 mRNA CTD PMID:17440010 NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815 		JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 affects expression ISO testosterone enanthate affects the expression of HTATSF1 mRNA CTD PMID:17440010 NCBI chr  X:139,972,742...139,986,923
Ensembl chr  X:139,972,742...139,986,923 		JBrowse link
G Hyal4 hyaluronidase 4 affects expression ISO testosterone enanthate affects the expression of HYAL4 mRNA CTD PMID:17440010 NCBI chr 4:54,221,728...54,240,364
Ensembl chr 4:54,221,728...54,240,364 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 affects expression ISO testosterone enanthate affects the expression of IDO1 mRNA CTD PMID:17440010 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ids iduronate 2-sulfatase affects expression ISO testosterone enanthate affects the expression of IDS mRNA CTD PMID:17440010 NCBI chr  X:154,070,781...154,093,681
Ensembl chr  X:154,070,781...154,091,444 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 affects expression ISO testosterone enanthate affects the expression of IFI27 mRNA CTD PMID:17440010 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781 		JBrowse link
G Ifi44l interferon-induced protein 44-like affects expression ISO testosterone enanthate affects the expression of IFI44L mRNA CTD PMID:17440010 NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:243,328,723...243,366,404 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 affects expression ISO testosterone enanthate affects the expression of IFIT3 mRNA CTD PMID:17440010 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP testosterone enanthate results in decreased expression of IGF1 mRNA CTD PMID:23085480 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression EXP testosterone enanthate results in increased expression of IGF1R mRNA CTD PMID:23085480 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression EXP testosterone enanthate results in increased expression of IGF2R mRNA CTD PMID:23085480 NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265 		JBrowse link
G Il10rb interleukin 10 receptor subunit beta affects expression ISO testosterone enanthate affects the expression of IL10RB mRNA CTD PMID:17440010 NCBI chr11:44,132,471...44,154,062
Ensembl chr11:44,132,189...44,154,053 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of IL1A protein] CTD PMID:30154949 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of IL1B protein] CTD PMID:30154949 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression 		EXP cordycepin inhibits the reaction [testosterone enanthate results in increased expression of IL6 protein]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of IL6 protein] CTD PMID:36015278 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Il6r interleukin 6 receptor affects expression ISO testosterone enanthate affects the expression of IL6R mRNA CTD PMID:17440010 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer affects expression ISO testosterone enanthate affects the expression of IL6ST mRNA CTD PMID:17440010 NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182 		JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 affects expression ISO testosterone enanthate affects the expression of INPPL1 mRNA CTD PMID:17440010 NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:165,595,063...165,609,503 		JBrowse link
G Insl3 insulin-like 3 multiple interactions
decreases expression 		ISO
EXP 		[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of INSL3 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of INSL3 mRNA
testosterone enanthate results in decreased expression of INSL3 mRNA 		CTD PMID:18160741 PMID:25603467 NCBI chr16:18,432,668...18,434,539 JBrowse link
G Ints6 integrator complex subunit 6 affects expression ISO testosterone enanthate affects the expression of INTS6 mRNA CTD PMID:17440010 NCBI chr15:41,080,584...41,224,350
Ensembl chr15:41,109,125...41,197,519 		JBrowse link
G Irf9 interferon regulatory factor 9 affects expression ISO testosterone enanthate affects the expression of IRF9 mRNA CTD PMID:17440010 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO testosterone enanthate affects the expression of ISG15 mRNA CTD PMID:17440010 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Itgav integrin subunit alpha V affects expression ISO testosterone enanthate affects the expression of ITGAV mRNA CTD PMID:17440010 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Jak1 Janus kinase 1 increases expression EXP testosterone enanthate results in increased expression of JAK1 mRNA CTD PMID:25603467 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 increases expression EXP testosterone enanthate results in increased expression of JAK2 mRNA CTD PMID:25603467 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jak3 Janus kinase 3 increases expression EXP testosterone enanthate results in increased expression of JAK3 mRNA CTD PMID:25603467 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 affects expression ISO testosterone enanthate affects the expression of KCNJ12 mRNA CTD PMID:17440010 NCBI chr10:46,196,110...46,245,008
Ensembl chr10:46,195,428...46,260,169 		JBrowse link
G Kdm5a lysine demethylase 5A affects expression ISO testosterone enanthate affects the expression of KDM5A mRNA CTD PMID:17440010 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121 		JBrowse link
G Kdm6a lysine demethylase 6A affects expression ISO testosterone enanthate affects the expression of KDM6A mRNA CTD PMID:17440010 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:6,920,343...7,059,960 		JBrowse link
G Klhl24 kelch-like family member 24 affects expression ISO testosterone enanthate affects the expression of KLHL24 mRNA CTD PMID:17440010 NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050 		JBrowse link
G Kmt2a lysine methyltransferase 2A affects expression ISO testosterone enanthate affects the expression of KMT2A mRNA CTD PMID:17440010 NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:54,013,547...54,089,317 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 affects expression ISO testosterone enanthate affects the expression of KPNB1 mRNA CTD PMID:17440010 NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,642,082...82,670,856 		JBrowse link
G Kras KRAS proto-oncogene, GTPase affects expression ISO testosterone enanthate affects the expression of KRAS mRNA CTD PMID:17440010 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Lama4 laminin subunit alpha 4 affects expression ISO testosterone enanthate affects the expression of LAMA4 mRNA CTD PMID:17440010 NCBI chr20:43,946,898...44,087,972
Ensembl chr20:43,946,898...44,087,972 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 affects expression ISO testosterone enanthate affects the expression of LAPTM5 mRNA CTD PMID:17440010 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927 		JBrowse link
G Ldaf1 lipid droplet assembly factor 1 affects expression ISO testosterone enanthate affects the expression of LDAF1 mRNA CTD PMID:17440010 NCBI chr 1:183,915,919...183,934,374
Ensembl chr 1:183,849,812...183,934,666 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression 		EXP Cyproterone Acetate inhibits the reaction [testosterone enanthate results in decreased expression of LHB protein]
testosterone enanthate results in decreased expression of LHB mRNA; testosterone enanthate results in decreased expression of LHB protein 		CTD PMID:20463352 PMID:21427060 PMID:23085480 PMID:25603467 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP testosterone enanthate results in decreased expression of LHCGR mRNA CTD PMID:21427060 PMID:25603467 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061 		JBrowse link
G Limk2 LIM domain kinase 2 affects expression ISO testosterone enanthate affects the expression of LIMK2 mRNA CTD PMID:17440010 NCBI chr14:82,384,256...82,509,755
Ensembl chr14:82,435,480...82,509,644 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 affects expression ISO testosterone enanthate affects the expression of LIMS1 mRNA CTD PMID:17440010 NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,852,996...26,961,606 		JBrowse link
G Loxl2 lysyl oxidase-like 2 affects expression ISO testosterone enanthate affects the expression of LOXL2 mRNA CTD PMID:17440010 NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842 		JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 affects expression ISO testosterone enanthate affects the expression of LPAR6 mRNA CTD PMID:17440010 NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783 		JBrowse link
G Lrrc8b leucine rich repeat containing 8 VRAC subunit B affects expression ISO testosterone enanthate affects the expression of LRRC8B mRNA CTD PMID:17440010 NCBI chr14:4,655,273...4,721,648
Ensembl chr14:4,655,273...4,721,076 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 affects expression ISO testosterone enanthate affects the expression of LTBP1 mRNA CTD PMID:17440010 NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 affects expression ISO testosterone enanthate affects the expression of LTBP3 mRNA CTD PMID:17440010 NCBI chr 1:212,458,362...212,475,302
Ensembl chr 1:212,459,185...212,475,302 		JBrowse link
G Luc7l3 LUC7 pre-mRNA splicing factor like 3 affects expression ISO testosterone enanthate affects the expression of LUC7L3 mRNA CTD PMID:17440010 NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429 		JBrowse link
G Lum lumican affects expression ISO testosterone enanthate affects the expression of LUM mRNA CTD PMID:17440010 NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO testosterone enanthate affects the expression of MACF1 mRNA CTD PMID:17440010 NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890 		JBrowse link
G Man2b2 mannosidase, alpha, class 2B, member 2 affects expression ISO testosterone enanthate affects the expression of MAN2B2 mRNA CTD PMID:17440010 NCBI chr14:78,193,797...78,218,802
Ensembl chr14:78,193,725...78,227,724 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression EXP testosterone enanthate results in decreased expression of MAPK3 mRNA CTD PMID:23085480 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapt microtubule-associated protein tau affects expression ISO testosterone enanthate affects the expression of MAPT mRNA CTD PMID:17440010 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate affects expression ISO testosterone enanthate affects the expression of MARCKS mRNA CTD PMID:17440010 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase affects expression ISO testosterone enanthate affects the expression of MBD4 mRNA CTD PMID:17440010 NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:150,565,655...150,577,578 		JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 affects expression ISO testosterone enanthate affects the expression of MBNL2 mRNA CTD PMID:17440010 NCBI chr15:103,792,134...103,949,827
Ensembl chr15:103,792,152...103,949,827 		JBrowse link
G Med8 mediator complex subunit 8 affects expression ISO testosterone enanthate affects the expression of MED8 mRNA CTD PMID:17440010 NCBI chr 5:137,234,028...137,234,912
Ensembl chr 5:137,229,367...137,246,666 		JBrowse link
G Mettl4 methyltransferase 4, N6-adenosine affects expression ISO testosterone enanthate affects the expression of METTL4 mRNA CTD PMID:17440010 NCBI chr 9:118,887,740...118,967,433
Ensembl chr 9:118,887,528...118,911,364 		JBrowse link
G Mlec malectin affects expression ISO testosterone enanthate affects the expression of MLEC mRNA CTD PMID:17440010 NCBI chr12:47,118,918...47,133,598
Ensembl chr12:47,118,855...47,130,064 		JBrowse link
G Mpdz multiple PDZ domain crumbs cell polarity complex component affects expression ISO testosterone enanthate affects the expression of MPDZ mRNA CTD PMID:17440010 NCBI chr 5:100,812,121...100,966,566
Ensembl chr 5:100,812,124...100,966,504 		JBrowse link
G Mphosph9 M-phase phosphoprotein 9 affects expression ISO testosterone enanthate affects the expression of MPHOSPH9 mRNA CTD PMID:17440010 NCBI chr12:37,936,442...38,007,053
Ensembl chr12:37,936,885...38,003,348 		JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 affects expression ISO testosterone enanthate affects the expression of MRPS31 mRNA CTD PMID:17440010 NCBI chr16:76,303,807...76,332,970
Ensembl chr16:76,301,645...76,333,065 		JBrowse link
G Mrps6 mitochondrial ribosomal protein S6 affects expression ISO testosterone enanthate affects the expression of MRPS6 mRNA CTD PMID:17440010 NCBI chr11:44,778,667...44,834,420
Ensembl chr11:44,781,554...44,834,962 		JBrowse link
G Msl2 MSL complex subunit 2 affects expression ISO testosterone enanthate affects the expression of MSL2 mRNA CTD PMID:17440010 NCBI chr 8:110,555,579...110,642,096
Ensembl chr 8:110,555,271...110,647,889 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of MSMO1 mRNA CTD PMID:18160741 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Msn moesin affects expression ISO testosterone enanthate affects the expression of MSN mRNA CTD PMID:17440010 NCBI chr  X:65,005,546...65,073,512
Ensembl chr  X:65,005,458...65,075,129 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 affects expression ISO testosterone enanthate affects the expression of MTUS1 mRNA CTD PMID:17440010 NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474 		JBrowse link
G Mx1 MX dynamin like GTPase 1 affects expression ISO testosterone enanthate affects the expression of MX1 mRNA CTD PMID:17440010 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904 		JBrowse link
G Mx2 MX dynamin like GTPase 2 affects expression ISO testosterone enanthate affects the expression of MX2 mRNA CTD PMID:17440010 NCBI chr11:50,375,101...50,399,373
Ensembl chr11:50,375,191...50,402,478 		JBrowse link
G Mxd4 Max dimerization protein 4 affects expression ISO testosterone enanthate affects the expression of MXD4 mRNA CTD PMID:17440010 NCBI chr14:80,786,768...80,800,790
Ensembl chr14:80,786,342...80,800,788 		JBrowse link
G Myh11 myosin heavy chain 11 affects expression ISO testosterone enanthate affects the expression of MYH11 mRNA CTD PMID:17440010 NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678 		JBrowse link
G Myh3 myosin heavy chain 3 affects expression ISO testosterone enanthate affects the expression of MYH3 mRNA CTD PMID:17440010 NCBI chr10:52,269,185...52,293,000
Ensembl chr10:52,269,185...52,293,000 		JBrowse link
G Myo9a myosin IXA affects expression ISO testosterone enanthate affects the expression of MYO9A mRNA CTD PMID:17440010 NCBI chr 8:69,044,853...69,248,094
Ensembl chr 8:69,044,885...69,245,231 		JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 affects expression ISO testosterone enanthate affects the expression of N4BP2L2 mRNA CTD PMID:17440010 NCBI chr12:4,972,967...5,038,027
Ensembl chr12:4,972,990...5,033,405 		JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit affects expression ISO testosterone enanthate affects the expression of NAA15 mRNA CTD PMID:17440010 NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 increases expression ISO testosterone enanthate results in increased expression of NCOA3 mRNA CTD PMID:17440010 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631 		JBrowse link
G Ndnf neuron-derived neurotrophic factor affects expression ISO testosterone enanthate affects the expression of NDNF mRNA CTD PMID:17440010 NCBI chr 4:96,274,147...96,311,624
Ensembl chr 4:96,274,147...96,311,624 		JBrowse link
G Ndrg2 NDRG family member 2 affects expression ISO testosterone enanthate affects the expression of NDRG2 mRNA CTD PMID:17440010 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125 		JBrowse link
G Nek1 NIMA-related kinase 1 affects expression ISO testosterone enanthate affects the expression of NEK1 mRNA CTD PMID:17440010 NCBI chr16:34,009,092...34,137,418
Ensembl chr16:34,009,094...34,128,576 		JBrowse link
G Nes nestin affects expression ISO testosterone enanthate affects the expression of NES mRNA CTD PMID:17440010 NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228 		JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 affects expression ISO testosterone enanthate affects the expression of NEURL1 mRNA CTD PMID:17440010 NCBI chr 1:256,008,012...256,094,219
Ensembl chr 1:256,008,160...256,094,224 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO testosterone enanthate results in increased expression of NFAT5 mRNA CTD PMID:17440010 NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418 		JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein affects expression ISO testosterone enanthate affects the expression of NFATC2IP mRNA CTD PMID:17440010 NCBI chr 1:190,385,416...190,403,309
Ensembl chr 1:190,387,437...190,402,413 		JBrowse link
G Nktr natural killer cell triggering receptor affects expression ISO testosterone enanthate affects the expression of NKTR mRNA CTD PMID:17440010 NCBI chr 8:130,255,541...130,298,001
Ensembl chr 8:130,259,461...130,298,008 		JBrowse link
G Nlk nemo like kinase affects expression ISO testosterone enanthate affects the expression of NLK mRNA CTD PMID:17440010 NCBI chr10:63,965,432...64,089,006 JBrowse link
G Nnmt nicotinamide N-methyltransferase affects expression ISO testosterone enanthate affects the expression of NNMT mRNA CTD PMID:17440010 NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression 		EXP [pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in decreased secretion of Nitrites; [pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in increased secretion of Dihydrotestosterone; [pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]] which results in increased secretion of Testosterone; [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Cyclic GMP; [testosterone enanthate results in increased expression of NOS2 mRNA] which results in increased abundance of Nitrites; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]; pimagedine inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; testosterone enanthate inhibits the reaction [Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]]; testosterone enanthate inhibits the reaction [Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]]; Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 mRNA]; Triptorelin Pamoate inhibits the reaction [testosterone enanthate results in increased expression of NOS2 protein]
testosterone enanthate results in increased expression of NOS2 mRNA; testosterone enanthate results in increased expression of NOS2 protein 		CTD PMID:20463352 PMID:23085480 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Npepps aminopeptidase puromycin sensitive affects expression ISO testosterone enanthate affects the expression of NPEPPS mRNA CTD PMID:17440010 NCBI chr10:82,687,869...82,770,363
Ensembl chr10:82,687,871...82,770,363 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression EXP testosterone enanthate results in decreased expression of NR0B1 mRNA CTD PMID:25603467 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP testosterone enanthate results in decreased expression of NR5A1 mRNA CTD PMID:21427060 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 affects expression ISO testosterone enanthate affects the expression of OAS2 mRNA CTD PMID:17440010 NCBI chr12:41,464,568...41,492,036
Ensembl chr12:41,467,315...41,495,881 		JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 affects expression ISO testosterone enanthate affects the expression of OAZ2 mRNA CTD PMID:17440010 NCBI chr 8:75,094,817...75,108,634
Ensembl chr 8:75,094,798...75,108,630 		JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression ISO testosterone enanthate affects the expression of OGDH mRNA CTD PMID:17440010 NCBI chr14:85,363,949...85,431,405
Ensembl chr14:85,364,014...85,432,271 		JBrowse link
G Ogfod2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 affects expression ISO testosterone enanthate affects the expression of OGFOD2 mRNA CTD PMID:17440010 NCBI chr12:38,143,329...38,146,630
Ensembl chr12:38,142,900...38,146,630 		JBrowse link
G Ogfr opioid growth factor receptor affects expression ISO testosterone enanthate affects the expression of OGFR mRNA CTD PMID:17440010 NCBI chr 3:188,080,743...188,087,028
Ensembl chr 3:188,080,042...188,087,471 		JBrowse link
G Orc4 origin recognition complex, subunit 4 affects expression ISO testosterone enanthate affects the expression of ORC4 mRNA CTD PMID:17440010 NCBI chr 3:53,700,046...53,743,293
Ensembl chr 3:53,703,615...53,742,264 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 affects expression ISO testosterone enanthate affects the expression of OSBPL8 mRNA CTD PMID:17440010 NCBI chr 7:48,483,259...48,636,151
Ensembl chr 7:48,483,022...48,636,151 		JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 affects expression ISO testosterone enanthate affects the expression of P3H4 mRNA CTD PMID:17440010 NCBI chr10:85,838,528...85,845,476
Ensembl chr10:85,838,528...85,845,476 		JBrowse link
G Pakap paralemmin A kinase anchor protein affects expression ISO testosterone enanthate affects the expression of PALM2AKAP2 mRNA CTD PMID:17440010 NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656 		JBrowse link
G Palld palladin, cytoskeletal associated protein affects expression ISO testosterone enanthate affects the expression of PALLD mRNA CTD PMID:17440010 NCBI chr16:33,238,943...33,632,236
Ensembl chr16:33,238,956...33,632,232 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PAPSS2 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of PAPSS2 mRNA CTD PMID:18160741 NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616 		JBrowse link
G Pard3 par-3 family cell polarity regulator affects expression ISO testosterone enanthate affects the expression of PARD3 mRNA CTD PMID:17440010 NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941 		JBrowse link
G Pcdh17 protocadherin 17 affects expression ISO testosterone enanthate affects the expression of PCDH17 mRNA CTD PMID:17440010 NCBI chr15:66,631,549...66,725,007
Ensembl chr15:66,633,142...66,722,105 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions 		EXP testosterone enanthate results in increased expression of PCNA protein
Finasteride inhibits the reaction [testosterone enanthate results in increased expression of PCNA protein] 		CTD PMID:36015278 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcyox1 prenylcysteine oxidase 1 affects expression ISO testosterone enanthate affects the expression of PCYOX1 mRNA CTD PMID:17440010 NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:120,388,180...120,400,382 		JBrowse link
G Pdcd4 programmed cell death 4 affects expression ISO testosterone enanthate affects the expression of PDCD4 mRNA CTD PMID:17440010 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP testosterone enanthate results in increased expression of PDE10A mRNA CTD PMID:20463352 PMID:21427060 NCBI chr 1:54,313,343...54,765,668
Ensembl chr 1:54,317,732...54,764,051 		JBrowse link
G Pde1c phosphodiesterase 1C increases expression EXP testosterone enanthate results in increased expression of PDE1C mRNA CTD PMID:20463352 PMID:21427060 NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:86,626,282...87,193,259 		JBrowse link
G Pde3a phosphodiesterase 3A increases expression EXP testosterone enanthate results in increased expression of PDE3A mRNA CTD PMID:20463352 PMID:21427060 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270 		JBrowse link
G Pde4a phosphodiesterase 4A increases expression EXP testosterone enanthate results in increased expression of PDE4A mRNA CTD PMID:21427060 PMID:25603467 NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:27,966,996...28,046,924 		JBrowse link
G Pde4b phosphodiesterase 4B increases expression EXP testosterone enanthate results in increased expression of PDE4B mRNA CTD PMID:21427060 PMID:25603467 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pde4d phosphodiesterase 4D increases expression EXP testosterone enanthate results in increased expression of PDE4D mRNA CTD PMID:25603467 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569 		JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein affects expression ISO testosterone enanthate affects the expression of PDE4DIP mRNA CTD PMID:17440010 NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869 		JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions
increases expression 		EXP [testosterone enanthate co-treated with Triptorelin Pamoate] results in increased expression of PDE5A mRNA; [testosterone enanthate co-treated with Triptorelin Pamoate] results in increased expression of PDE5A protein; Cyproterone Acetate inhibits the reaction [testosterone enanthate results in increased expression of PDE5A mRNA]
testosterone enanthate results in increased expression of PDE5A mRNA; testosterone enanthate results in increased expression of PDE5A protein 		CTD PMID:20463352 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298 		JBrowse link
G Pde6d phosphodiesterase 6D increases expression EXP testosterone enanthate results in increased expression of PDE6D mRNA CTD PMID:20463352 NCBI chr 9:94,640,932...94,685,918
Ensembl chr 9:94,640,932...94,685,918 		JBrowse link
G Pde7a phosphodiesterase 7A increases expression EXP testosterone enanthate results in increased expression of PDE7A mRNA CTD PMID:21427060 NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890 		JBrowse link
G Pde7b phosphodiesterase 7B increases metabolic processing
increases hydrolysis 		ISO PDE7B protein results in increased metabolism of testosterone enanthate
PDE7B protein results in increased hydrolysis of testosterone enanthate 		CTD PMID:21383644 NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456 		JBrowse link
G Pde8b phosphodiesterase 8B increases expression EXP testosterone enanthate results in increased expression of PDE8B mRNA CTD PMID:21427060 NCBI chr 2:28,009,841...28,244,050
Ensembl chr 2:28,011,359...28,244,327 		JBrowse link
G Pde9a phosphodiesterase 9A increases expression EXP testosterone enanthate results in increased expression of PDE9A mRNA CTD PMID:20463352 NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression ISO testosterone enanthate affects the expression of PDK4 mRNA CTD PMID:17440010 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 affects expression ISO testosterone enanthate affects the expression of PDP1 mRNA CTD PMID:17440010 NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960 		JBrowse link
G Pfkl phosphofructokinase, liver type affects expression ISO testosterone enanthate affects the expression of PFKL mRNA CTD PMID:17440010 NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966 		JBrowse link
G Pgghg protein-glucosylgalactosylhydroxylysine glucosidase affects expression ISO testosterone enanthate affects the expression of PGGHG mRNA CTD PMID:17440010 NCBI chr 1:205,467,179...205,474,185
Ensembl chr 1:205,467,993...205,474,183 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PGRMC1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of PGRMC1 mRNA CTD PMID:18160741 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805 		JBrowse link
G Phf14 PHD finger protein 14 affects expression ISO testosterone enanthate affects the expression of PHF14 mRNA CTD PMID:17440010 NCBI chr 4:40,975,897...41,162,043
Ensembl chr 4:40,975,439...41,162,043 		JBrowse link
G Phf3 PHD finger protein 3 affects expression ISO testosterone enanthate affects the expression of PHF3 mRNA CTD PMID:17440010 NCBI chr 9:40,559,929...40,632,096
Ensembl chr 9:40,559,929...40,632,056 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 affects expression ISO testosterone enanthate affects the expression of PHLDA1 mRNA CTD PMID:17440010 NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein affects expression ISO testosterone enanthate affects the expression of PICALM mRNA CTD PMID:17440010 NCBI chr 1:153,468,982...153,550,086
Ensembl chr 1:153,469,202...153,550,237 		JBrowse link
G Pitpna phosphatidylinositol transfer protein, alpha affects expression ISO testosterone enanthate affects the expression of PITPNA mRNA CTD PMID:17440010 NCBI chr10:60,929,050...60,969,614
Ensembl chr10:60,929,007...60,971,830 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 affects expression ISO testosterone enanthate affects the expression of PLEKHA1 mRNA CTD PMID:17440010 NCBI chr 1:194,858,239...194,909,418
Ensembl chr 1:194,851,547...194,909,413 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 affects expression ISO testosterone enanthate affects the expression of PLOD2 mRNA CTD PMID:17440010 NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022 		JBrowse link
G Plpp3 phospholipid phosphatase 3 affects expression ISO testosterone enanthate affects the expression of PLPP3 mRNA CTD PMID:17440010 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Pmvk phosphomevalonate kinase affects expression ISO testosterone enanthate affects the expression of PMVK mRNA CTD PMID:17440010 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression EXP testosterone enanthate results in increased expression of PPARGC1A mRNA CTD PMID:25603467 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression EXP testosterone enanthate results in increased expression of PPARGC1B mRNA CTD PMID:25603467 NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466 		JBrowse link
G Ppib peptidylprolyl isomerase B affects expression ISO testosterone enanthate affects the expression of PPIB mRNA CTD PMID:17440010 NCBI chr 8:75,498,966...75,504,823
Ensembl chr 8:75,498,797...75,504,847 		JBrowse link
G Ppig peptidylprolyl isomerase G affects expression ISO testosterone enanthate affects the expression of PPIG mRNA CTD PMID:17440010 NCBI chr 3:74,891,846...74,923,010
Ensembl chr 3:74,891,846...74,920,750 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A affects expression ISO testosterone enanthate affects the expression of PPM1A mRNA CTD PMID:17440010 NCBI chr 6:97,174,955...97,216,585
Ensembl chr 6:97,174,916...97,216,574 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A affects expression ISO testosterone enanthate affects the expression of PPP1R12A mRNA CTD PMID:17440010 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157 		JBrowse link
G Ppp1r3a protein phosphatase 1, regulatory subunit 3A affects expression ISO testosterone enanthate affects the expression of PPP1R3A mRNA CTD PMID:17440010 NCBI chr 4:43,905,648...43,946,236
Ensembl chr 4:43,905,648...43,946,236 		JBrowse link
G Ppp1r7 protein phosphatase 1, regulatory subunit 7 affects expression ISO testosterone enanthate affects the expression of PPP1R7 mRNA CTD PMID:17440010 NCBI chr 9:101,333,472...101,358,589
Ensembl chr 9:101,333,497...101,360,959 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A affects expression ISO testosterone enanthate affects the expression of PPP1R9A mRNA CTD PMID:17440010 NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,988,827...34,258,927 		JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit affects expression ISO testosterone enanthate affects the expression of PPP4C mRNA CTD PMID:17440010 NCBI chr 1:190,823,447...190,830,247
Ensembl chr 1:190,823,486...190,830,168 		JBrowse link
G Prf1 perforin 1 affects expression ISO testosterone enanthate affects the expression of PRF1 mRNA CTD PMID:17440010 NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,788,972...29,795,124 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation
multiple interactions 		EXP testosterone enanthate results in decreased phosphorylation of PRKAA1 protein
cordycepin inhibits the reaction [testosterone enanthate results in decreased phosphorylation of PRKAA1 protein]; Finasteride inhibits the reaction [testosterone enanthate results in decreased phosphorylation of PRKAA1 protein] 		CTD PMID:36015278 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 affects expression
multiple interactions
decreases phosphorylation 		ISO
EXP 		testosterone enanthate affects the expression of PRKAA2 mRNA
cordycepin inhibits the reaction [testosterone enanthate results in decreased phosphorylation of PRKAA2 protein]; Finasteride inhibits the reaction [testosterone enanthate results in decreased phosphorylation of PRKAA2 protein] 		CTD PMID:17440010 PMID:36015278 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 affects expression ISO testosterone enanthate affects the expression of PRKAB2 mRNA CTD PMID:17440010 NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta affects expression ISO
EXP 		testosterone enanthate affects the expression of PRKACB mRNA CTD PMID:17440010 PMID:25603467 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha affects expression EXP testosterone enanthate affects the expression of PRKAR1A mRNA CTD PMID:25603467 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha decreases expression
affects expression 		EXP
ISO 		testosterone enanthate results in decreased expression of PRKAR2A mRNA
testosterone enanthate affects the expression of PRKAR2A mRNA 		CTD PMID:17440010 PMID:25603467 NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta affects expression EXP testosterone enanthate affects the expression of PRKAR2B mRNA CTD PMID:25603467 NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411 		JBrowse link
G Prkca protein kinase C, alpha decreases expression EXP testosterone enanthate results in decreased expression of PRKCA mRNA CTD PMID:25603467 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 multiple interactions
affects expression
decreases expression 		EXP
ISO 		testosterone enanthate promotes the reaction [Triptorelin Pamoate results in decreased expression of PRKG1 mRNA]; testosterone enanthate promotes the reaction [Triptorelin Pamoate results in decreased expression of PRKG1 protein]
testosterone enanthate affects the expression of PRKG1 mRNA
testosterone enanthate results in decreased expression of PRKG1 mRNA; testosterone enanthate results in decreased expression of PRKG1 protein 		CTD PMID:17440010 PMID:20463352 PMID:23085480 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005 		JBrowse link
G Prl prolactin affects expression EXP testosterone enanthate affects the expression of PRL mRNA CTD PMID:25603467 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Prlr prolactin receptor decreases expression EXP testosterone enanthate results in decreased expression of PRLR mRNA CTD PMID:25603467 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa decreases expression ISO testosterone enanthate results in decreased expression of PROC protein CTD PMID:8585008 NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964 		JBrowse link
G Prok1 prokineticin 1 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of PROK1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of PROK1 mRNA CTD PMID:18160741 NCBI chr 2:197,538,747...197,547,550
Ensembl chr 2:197,537,068...197,547,550 		JBrowse link
G Pros1 protein S decreases expression ISO testosterone enanthate results in decreased expression of PROS1 protein CTD PMID:8585008 NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852 		JBrowse link
G Prox1 prospero homeobox 1 affects expression ISO testosterone enanthate affects the expression of PROX1 mRNA CTD PMID:17440010 NCBI chr13:104,196,615...104,251,007
Ensembl chr13:104,200,378...104,250,975 		JBrowse link
G Prps2 phosphoribosyl pyrophosphate synthetase 2 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate] results in decreased expression of PRPS2 mRNA CTD PMID:18160741 NCBI chr  X:30,592,845...30,630,127
Ensembl chr  X:30,593,019...30,630,126 		JBrowse link
G Prrc2c proline-rich coiled-coil 2C affects expression ISO testosterone enanthate affects the expression of PRRC2C mRNA CTD PMID:17440010 NCBI chr13:77,537,226...77,606,926
Ensembl chr13:77,537,814...77,607,001 		JBrowse link
G Prss22 serine protease 22 affects expression ISO testosterone enanthate affects the expression of PRSS22 mRNA CTD PMID:17440010 NCBI chr10:13,533,725...13,538,435
Ensembl chr10:13,533,725...13,538,435 		JBrowse link
G Prune2 prune homolog 2 with BCH domain affects expression ISO testosterone enanthate affects the expression of PRUNE2 mRNA CTD PMID:17440010 NCBI chr 1:223,779,617...224,130,058
Ensembl chr 1:223,969,102...224,051,592 		JBrowse link
G Psme4 proteasome activator subunit 4 affects expression ISO testosterone enanthate affects the expression of PSME4 mRNA CTD PMID:17440010 NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328 		JBrowse link
G Psph phosphoserine phosphatase affects expression ISO testosterone enanthate affects the expression of PSPH mRNA CTD PMID:17440010 NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 affects expression ISO testosterone enanthate affects the expression of PTBP1 mRNA CTD PMID:17440010 NCBI chr 7:10,493,199...10,502,957
Ensembl chr 7:10,493,200...10,502,957 		JBrowse link
G Ptcd2 pentatricopeptide repeat domain 2 affects expression ISO testosterone enanthate affects the expression of PTCD2 mRNA CTD PMID:17440010 NCBI chr 2:32,446,441...32,474,114
Ensembl chr 2:32,446,182...32,474,285 		JBrowse link
G Ptma prothymosin alpha affects expression ISO testosterone enanthate affects the expression of PTMA mRNA CTD PMID:17440010 NCBI chr 9:94,624,194...94,628,276
Ensembl chr 9:94,624,196...94,628,276 		JBrowse link
G Ptn pleiotrophin affects expression ISO testosterone enanthate affects the expression of PTN mRNA CTD PMID:17440010 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482 		JBrowse link
G Ptpn4 protein tyrosine phosphatase, non-receptor type 4 affects expression ISO testosterone enanthate affects the expression of PTPN4 mRNA CTD PMID:17440010 NCBI chr13:33,324,808...33,504,957
Ensembl chr13:33,324,808...33,504,957 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D affects expression ISO testosterone enanthate affects the expression of PTPRD mRNA CTD PMID:17440010 NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903 		JBrowse link
G Pvalb parvalbumin affects expression ISO testosterone enanthate affects the expression of PVALB mRNA CTD PMID:17440010 NCBI chr 7:111,653,820...111,668,469
Ensembl chr 7:111,653,111...111,668,446 		JBrowse link
G Pwwp3a PWWP domain containing 3A, DNA repair factor affects expression ISO testosterone enanthate affects the expression of PWWP3A mRNA CTD PMID:17440010 NCBI chr 7:10,115,865...10,132,696
Ensembl chr 7:10,115,866...10,130,925 		JBrowse link
G Pxdn peroxidasin affects expression ISO testosterone enanthate affects the expression of PXDN mRNA CTD PMID:17440010 NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942 		JBrowse link
G Rab14 RAB14, member RAS oncogene family affects expression ISO testosterone enanthate affects the expression of RAB14 mRNA CTD PMID:17440010 NCBI chr 3:38,899,430...38,920,572
Ensembl chr 3:38,901,400...38,912,273 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family affects expression ISO testosterone enanthate affects the expression of RAB27A mRNA CTD PMID:17440010 NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262 		JBrowse link
G Rad50 RAD50 double strand break repair protein affects expression ISO testosterone enanthate affects the expression of RAD50 mRNA CTD PMID:17440010 NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100 		JBrowse link
G Ranbp2 RAN binding protein 2 affects expression ISO testosterone enanthate affects the expression of RANBP2 mRNA CTD PMID:17440010 NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571 		JBrowse link
G Rap2a RAP2A, member of RAS oncogene family affects expression ISO testosterone enanthate affects the expression of RAP2A mRNA CTD PMID:17440010 NCBI chr15:104,003,744...104,004,234 JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 affects expression ISO testosterone enanthate affects the expression of RAPGEF2 mRNA CTD PMID:17440010 NCBI chr 2:166,505,868...166,728,139
Ensembl chr 2:166,505,868...166,726,698 		JBrowse link
G Rbbp5 RB binding protein 5, histone lysine methyltransferase complex subunit affects expression ISO testosterone enanthate affects the expression of RBBP5 mRNA CTD PMID:17440010 NCBI chr13:46,464,389...46,494,244
Ensembl chr13:46,464,389...46,491,238 		JBrowse link
G Rbl2 RB transcriptional corepressor like 2 affects expression ISO testosterone enanthate affects the expression of RBL2 mRNA CTD PMID:17440010 NCBI chr19:32,049,690...32,096,467
Ensembl chr19:32,049,691...32,096,411 		JBrowse link
G Rbm25 RNA binding motif protein 25 affects expression ISO testosterone enanthate affects the expression of RBM25 mRNA CTD PMID:17440010 NCBI chr 6:108,993,119...109,050,159
Ensembl chr 6:109,002,869...109,050,159 		JBrowse link
G Rbm41 RNA binding motif protein 41 affects expression ISO testosterone enanthate affects the expression of RBM41 mRNA CTD PMID:17440010 NCBI chr  X:108,394,323...108,448,969
Ensembl chr  X:108,397,176...108,448,969 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of RELA protein]; cordycepin inhibits the reaction [testosterone enanthate results in increased expression of RELA protein]; Finasteride inhibits the reaction [testosterone enanthate results in increased expression of RELA protein] CTD PMID:30154949 PMID:36015278 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Retreg3 reticulophagy regulator family member 3 affects expression ISO testosterone enanthate affects the expression of RETREG3 mRNA CTD PMID:17440010 NCBI chr10:86,529,048...86,552,873
Ensembl chr10:86,529,055...86,552,990 		JBrowse link
G Rgn regucalcin affects expression ISO testosterone enanthate affects the expression of RGN mRNA CTD PMID:17440010 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251 		JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of RHOB mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of RHOB mRNA CTD PMID:18160741 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 affects expression ISO testosterone enanthate affects the expression of RHOBTB3 mRNA CTD PMID:17440010 NCBI chr 2:7,094,972...7,201,507
Ensembl chr 2:7,095,253...7,150,906 		JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase affects expression ISO testosterone enanthate affects the expression of RNGTT mRNA CTD PMID:17440010 NCBI chr 5:52,503,335...52,709,604
Ensembl chr 5:52,503,313...52,709,597 		JBrowse link
G Rora RAR-related orphan receptor A increases expression ISO testosterone enanthate results in increased expression of RORA mRNA CTD PMID:17440010 NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730 		JBrowse link
G Rpl30 ribosomal protein L30 affects expression ISO testosterone enanthate affects the expression of RPL30 mRNA CTD PMID:17440010 NCBI chr 7:67,533,420...67,536,555
Ensembl chr 7:67,465,332...67,536,555 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator affects expression ISO testosterone enanthate affects the expression of RRAD mRNA CTD PMID:17440010 NCBI chr19:360,581...363,874
Ensembl chr19:360,973...363,871 		JBrowse link
G Rrbp1 ribosome binding protein 1 affects expression ISO testosterone enanthate affects the expression of RRBP1 mRNA CTD PMID:17440010 NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255 		JBrowse link
G Rrp7a ribosomal RNA processing 7 homolog A affects expression ISO testosterone enanthate affects the expression of RRP7A mRNA CTD PMID:17440010 NCBI chr 7:116,142,976...116,152,874
Ensembl chr 7:116,136,385...116,152,864 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 affects expression ISO testosterone enanthate affects the expression of RSAD2 mRNA CTD PMID:17440010 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320 		JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 affects expression ISO testosterone enanthate affects the expression of RSL1D1 mRNA CTD PMID:17440010 NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566 		JBrowse link
G Rsrc1 arginine and serine rich coiled-coil 1 affects expression ISO testosterone enanthate affects the expression of RSRC1 mRNA CTD PMID:17440010 NCBI chr 2:153,536,839...153,942,825
Ensembl chr 2:153,541,161...153,942,824 		JBrowse link
G RT1-Ba RT1 class II, locus Ba affects expression ISO testosterone enanthate affects the expression of HLA-DQA1 mRNA CTD PMID:17440010 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-Bb RT1 class II, locus Bb affects expression ISO testosterone enanthate affects the expression of HLA-DQB1 mRNA CTD PMID:17440010 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects expression ISO testosterone enanthate affects the expression of HLA-DPA1 mRNA CTD PMID:17440010 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G Rufy3 RUN and FYVE domain containing 3 affects expression ISO testosterone enanthate affects the expression of RUFY3 mRNA CTD PMID:17440010 NCBI chr14:19,715,593...19,790,530
Ensembl chr14:19,715,593...19,790,608 		JBrowse link
G Rxrb retinoid X receptor beta affects expression ISO testosterone enanthate affects the expression of RXRB mRNA CTD PMID:17440010 NCBI chr20:4,818,707...4,824,968
Ensembl chr20:4,818,709...4,825,359 		JBrowse link
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein affects expression ISO testosterone enanthate affects the expression of SART3 mRNA CTD PMID:17440010 NCBI chr12:48,519,579...48,547,584
Ensembl chr12:48,519,849...48,547,583 		JBrowse link
G Scaf11 SR-related CTD-associated factor 11 affects expression ISO testosterone enanthate affects the expression of SCAF11 mRNA CTD PMID:17440010 NCBI chr 7:129,450,872...129,503,280
Ensembl chr 7:129,417,955...129,503,280 		JBrowse link
G Scamp1 secretory carrier membrane protein 1 affects expression ISO testosterone enanthate affects the expression of SCAMP1 mRNA CTD PMID:17440010 NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP testosterone enanthate results in decreased expression of SCARB1 mRNA CTD PMID:21427060 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Scd stearoyl-CoA desaturase affects expression ISO testosterone enanthate affects the expression of SCD mRNA CTD PMID:17440010 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scpep1 serine carboxypeptidase 1 affects expression ISO testosterone enanthate affects the expression of SCPEP1 mRNA CTD PMID:17440010 NCBI chr10:74,200,491...74,230,107
Ensembl chr10:74,200,491...74,230,241 		JBrowse link
G Scrg1 stimulator of chondrogenesis 1 affects expression ISO testosterone enanthate affects the expression of SCRG1 mRNA CTD PMID:17440010 NCBI chr16:37,770,739...37,799,010
Ensembl chr16:37,770,739...37,799,010 		JBrowse link
G Sec14l1 SEC14-like lipid binding 1 affects expression ISO testosterone enanthate affects the expression of SEC14L1 mRNA CTD PMID:17440010 NCBI chr10:102,818,693...102,865,841
Ensembl chr10:102,818,693...102,865,839 		JBrowse link
G Sec23b Sec23 homolog B, COPII coat complex component affects expression ISO testosterone enanthate affects the expression of SEC23B mRNA CTD PMID:17440010 NCBI chr 3:152,392,340...152,434,813
Ensembl chr 3:152,392,308...152,434,800 		JBrowse link
G Sec23ip SEC23 interacting protein affects expression ISO testosterone enanthate affects the expression of SEC23IP mRNA CTD PMID:17440010 NCBI chr 1:192,751,379...192,794,345
Ensembl chr 1:192,751,454...192,794,969 		JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 affects expression ISO testosterone enanthate affects the expression of SEC61A1 mRNA CTD PMID:17440010 NCBI chr 4:122,530,785...122,545,141
Ensembl chr 4:122,530,789...122,545,141 		JBrowse link
G Sel1l3 SEL1L family member 3 affects expression ISO testosterone enanthate affects the expression of SEL1L3 mRNA CTD PMID:17440010 NCBI chr14:61,988,350...62,095,542
Ensembl chr14:61,988,346...62,095,542 		JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 affects expression ISO testosterone enanthate affects the expression of SERBP1 mRNA CTD PMID:17440010 NCBI chr 4:97,731,200...97,748,438
Ensembl chr 4:97,731,277...97,751,518 		JBrowse link
G Serpina3n serpin family A member 3N affects expression ISO testosterone enanthate affects the expression of SERPINA3 mRNA CTD PMID:17440010 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415 		JBrowse link
G Serpinc1 serpin family C member 1 increases expression ISO testosterone enanthate results in increased expression of SERPINC1 protein CTD PMID:8585008 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 affects expression ISO testosterone enanthate affects the expression of SF3B1 mRNA CTD PMID:17440010 NCBI chr 9:63,986,829...64,026,723
Ensembl chr 9:63,986,829...64,026,719 		JBrowse link
G Sfxn3 sideroflexin 3 affects expression ISO testosterone enanthate affects the expression of SFXN3 mRNA CTD PMID:17440010 NCBI chr 1:253,856,935...253,866,219
Ensembl chr 1:253,856,882...253,887,542 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 affects expression ISO testosterone enanthate affects the expression of SGK3 mRNA CTD PMID:17440010 NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:14,126,257...14,198,331 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 affects expression ISO testosterone enanthate affects the expression of SLC16A7 mRNA CTD PMID:17440010 NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386 		JBrowse link
G Slc25a16 solute carrier family 25 member 16 affects expression ISO testosterone enanthate affects the expression of SLC25A16 mRNA CTD PMID:17440010 NCBI chr20:25,659,847...25,717,080
Ensembl chr20:25,660,339...25,689,285
Ensembl chr20:25,660,339...25,689,285 		JBrowse link
G Slc35d1 solute carrier family 35 member D1 affects expression ISO testosterone enanthate affects the expression of SLC35D1 mRNA CTD PMID:17440010 NCBI chr 5:123,157,739...123,210,350
Ensembl chr 5:123,155,407...123,210,073 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 affects expression ISO testosterone enanthate affects the expression of SLC38A4 mRNA CTD PMID:17440010 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:130,023,980...130,082,097 		JBrowse link
G Slc38a6 solute carrier family 38, member 6 affects expression ISO testosterone enanthate affects the expression of SLC38A6 mRNA CTD PMID:17440010 NCBI chr 6:97,723,526...97,814,394
Ensembl chr 6:97,723,471...97,785,791 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 affects expression ISO testosterone enanthate affects the expression of SLC4A7 mRNA CTD PMID:17440010 NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292 		JBrowse link
G Slc5a2 solute carrier family 5 member 2 decreases expression EXP testosterone enanthate results in decreased expression of SLC5A2 protein CTD PMID:22262063 NCBI chr 1:192,277,621...192,283,742
Ensembl chr 1:192,277,621...192,283,742 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression ISO testosterone enanthate affects the expression of SLCO1A2 mRNA CTD PMID:17440010 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased phosphorylation of SMAD2 protein] CTD PMID:30154949 NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388 		JBrowse link
G Smad4 SMAD family member 4 affects expression ISO testosterone enanthate affects the expression of SMAD4 mRNA CTD PMID:17440010 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684 		JBrowse link
G Smad5 SMAD family member 5 affects expression ISO testosterone enanthate affects the expression of SMAD5 mRNA CTD PMID:17440010 NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 affects expression ISO testosterone enanthate affects the expression of SMC2 mRNA CTD PMID:17440010 NCBI chr 5:71,592,428...71,648,636
Ensembl chr 5:71,602,308...71,648,632 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 affects expression ISO testosterone enanthate affects the expression of SMC3 mRNA CTD PMID:17440010 NCBI chr 1:262,606,731...262,649,832
Ensembl chr 1:262,607,080...262,649,825 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 affects expression ISO testosterone enanthate affects the expression of SMC5 mRNA CTD PMID:17440010 NCBI chr 1:230,195,894...230,265,677
Ensembl chr 1:230,195,894...230,265,621 		JBrowse link
G Smg1 SMG1, nonsense mediated mRNA decay associated PI3K related kinase affects expression ISO testosterone enanthate affects the expression of SMG1 mRNA CTD PMID:17440010 NCBI chr 1:181,876,134...181,977,894
Ensembl chr 1:181,876,134...181,977,894 		JBrowse link
G Snap29 synaptosome associated protein 29 affects expression ISO testosterone enanthate affects the expression of SNAP29 mRNA CTD PMID:17440010 NCBI chr11:97,082,721...97,113,195
Ensembl chr11:97,082,739...97,113,195 		JBrowse link
G Snapc1 small nuclear RNA activating complex, polypeptide 1 affects expression ISO testosterone enanthate affects the expression of SNAPC1 mRNA CTD PMID:17440010 NCBI chr 6:98,420,588...98,442,065
Ensembl chr 6:98,420,340...98,442,489 		JBrowse link
G Snca synuclein alpha affects expression ISO testosterone enanthate affects the expression of SNCA mRNA CTD PMID:17440010 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315 		JBrowse link
G Snrnp35 small nuclear ribonucleoprotein U11/U12 subunit 35 affects expression ISO testosterone enanthate affects the expression of SNRNP35 mRNA CTD PMID:17440010 NCBI chr12:37,773,052...37,781,635
Ensembl chr12:37,771,759...37,783,908 		JBrowse link
G Snrpe small nuclear ribonucleoprotein polypeptide E affects expression ISO testosterone enanthate affects the expression of SNRPE mRNA CTD PMID:17440010 NCBI chr13:47,596,324...47,609,390
Ensembl chr 8:129,294,325...129,294,603
Ensembl chr13:129,294,325...129,294,603 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N affects expression ISO testosterone enanthate affects the expression of SNRPN mRNA CTD PMID:17440010 NCBI chr 1:120,316,846...120,338,919
Ensembl chr 1:120,315,556...120,323,924 		JBrowse link
G Sod1 superoxide dismutase 1 decreases activity
multiple interactions 		EXP testosterone enanthate results in decreased activity of SOD1 protein
cordycepin inhibits the reaction [testosterone enanthate results in decreased activity of SOD1 protein]; Finasteride inhibits the reaction [testosterone enanthate results in decreased activity of SOD1 protein] 		CTD PMID:36015278 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 affects expression ISO testosterone enanthate affects the expression of SORBS1 mRNA CTD PMID:17440010 NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:249,057,324...249,279,608 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 affects expression ISO testosterone enanthate affects the expression of SOS1 mRNA CTD PMID:17440010 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 affects expression ISO testosterone enanthate affects the expression of SOS2 mRNA CTD PMID:17440010 NCBI chr 6:93,778,971...93,892,161
Ensembl chr 6:93,778,971...93,892,811 		JBrowse link
G Sox4 SRY-box transcription factor 4 affects expression ISO testosterone enanthate affects the expression of SOX4 mRNA CTD PMID:17440010 NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024 		JBrowse link
G Sp110 SP110 nuclear body protein affects expression ISO testosterone enanthate affects the expression of SP110 mRNA CTD PMID:17440010 NCBI chr 9:93,648,574...93,673,476
Ensembl chr 9:93,648,575...93,670,659 		JBrowse link
G Spag9 sperm associated antigen 9 affects expression ISO testosterone enanthate affects the expression of SPAG9 mRNA CTD PMID:17440010 NCBI chr10:79,440,311...79,574,709
Ensembl chr10:79,440,377...79,575,258 		JBrowse link
G Spen spen family transcriptional repressor increases expression ISO testosterone enanthate results in increased expression of SPEN mRNA CTD PMID:17440010 NCBI chr 5:159,058,258...159,131,789
Ensembl chr 5:159,058,258...159,165,934 		JBrowse link
G Sqstm1 sequestosome 1 affects expression ISO testosterone enanthate affects the expression of SQSTM1 mRNA CTD PMID:17440010 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srpk2 SRSF protein kinase 2 affects expression ISO testosterone enanthate affects the expression of SRPK2 mRNA CTD PMID:17440010 NCBI chr 4:12,356,983...12,548,345
Ensembl chr 4:12,357,053...12,548,342 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked affects expression ISO testosterone enanthate affects the expression of SRPX mRNA CTD PMID:17440010 NCBI chr  X:15,349,498...15,420,389
Ensembl chr  X:15,349,440...15,420,392 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 affects expression ISO testosterone enanthate affects the expression of SRRM2 mRNA CTD PMID:17440010 NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 affects expression ISO testosterone enanthate affects the expression of SRSF6 mRNA CTD PMID:17440010 NCBI chr 3:172,009,072...172,014,395
Ensembl chr 3:172,009,061...172,014,392 		JBrowse link
G Ssb small RNA binding exonuclease protection factor La affects expression ISO testosterone enanthate affects the expression of SSB mRNA CTD PMID:17440010 NCBI chr 3:75,024,385...75,034,016
Ensembl chr 3:75,024,474...75,034,031 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 affects expression ISO testosterone enanthate affects the expression of SSBP1 mRNA CTD PMID:17440010 NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700 		JBrowse link
G Sspn sarcospan affects expression ISO testosterone enanthate affects the expression of SSPN mRNA CTD PMID:17440010 NCBI chr 4:180,620,762...180,666,893
Ensembl chr 4:180,627,848...180,662,284 		JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression ISO testosterone enanthate affects the expression of ST3GAL6 mRNA CTD PMID:17440010 NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720 		JBrowse link
G St7 suppression of tumorigenicity 7 affects expression ISO testosterone enanthate affects the expression of ST7 mRNA CTD PMID:17440010 NCBI chr 4:47,007,568...47,255,639
Ensembl chr 4:47,008,095...47,255,637 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions 		EXP
ISO 		testosterone enanthate results in decreased expression of STAR mRNA; testosterone enanthate results in decreased expression of STAR protein
[cetrorelix co-treated with testosterone enanthate] results in decreased expression of STAR mRNA 		CTD PMID:18160741 PMID:21427060 PMID:25603467 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 affects expression ISO testosterone enanthate affects the expression of STAT1 mRNA CTD PMID:17440010 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stk10 serine/threonine kinase 10 affects expression ISO testosterone enanthate affects the expression of STK10 mRNA CTD PMID:17440010 NCBI chr10:17,622,149...17,716,337
Ensembl chr10:17,622,162...17,716,332 		JBrowse link
G Stk38 serine/threonine kinase 38 affects expression ISO testosterone enanthate affects the expression of STK38 mRNA CTD PMID:17440010 NCBI chr20:7,035,923...7,070,657
Ensembl chr20:7,035,933...7,069,711 		JBrowse link
G Strn3 striatin 3 affects expression ISO testosterone enanthate affects the expression of STRN3 mRNA CTD PMID:17440010 NCBI chr 6:74,783,156...74,869,473
Ensembl chr 6:74,783,156...74,869,473 		JBrowse link
G Sugp2 SURP and G patch domain containing 2 affects expression ISO testosterone enanthate affects the expression of SUGP2 mRNA CTD PMID:17440010 NCBI chr16:19,193,910...19,225,364
Ensembl chr16:19,198,831...19,225,292 		JBrowse link
G Sycp1 synaptonemal complex protein 1 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of SYCP1 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of SYCP1 mRNA CTD PMID:18160741 NCBI chr 2:192,985,164...193,145,234
Ensembl chr 2:192,984,621...193,145,421 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein affects expression ISO testosterone enanthate affects the expression of SYNCRIP mRNA CTD PMID:17440010 NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:98,282,358...98,315,386 		JBrowse link
G Taf4b TATA-box binding protein associated factor 4b multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of TAF4B mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of TAF4B mRNA CTD PMID:18160741 NCBI chr18:6,227,299...6,360,970
Ensembl chr18:6,227,345...6,356,275 		JBrowse link
G Tbx1 T-box transcription factor 1 affects expression ISO testosterone enanthate affects the expression of TBX1 mRNA CTD PMID:17440010 NCBI chr11:95,913,610...95,923,392
Ensembl chr11:95,913,610...95,923,392 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 affects expression ISO testosterone enanthate affects the expression of TCAF1 mRNA CTD PMID:17440010 NCBI chr 4:72,589,710...72,639,304
Ensembl chr 4:72,589,710...72,639,475 		JBrowse link
G Tcap titin-cap affects expression ISO testosterone enanthate affects the expression of TCAP mRNA CTD PMID:17440010 NCBI chr10:83,878,006...83,879,174
Ensembl chr10:83,876,939...83,879,483 		JBrowse link
G Tcf25 TCF25 ribosome quality control complex subunit affects expression ISO testosterone enanthate affects the expression of TCF25 mRNA CTD PMID:17440010 NCBI chr19:68,323,789...68,358,226
Ensembl chr19:68,323,867...68,358,240 		JBrowse link
G Tcf4 transcription factor 4 increases expression ISO testosterone enanthate results in increased expression of TCF4 mRNA CTD PMID:17440010 NCBI chr18:65,216,840...65,563,186
Ensembl chr18:65,216,849...65,558,401 		JBrowse link
G Tcof1 treacle ribosome biogenesis factor 1 affects expression ISO testosterone enanthate affects the expression of TCOF1 mRNA CTD PMID:17440010 NCBI chr18:56,537,437...56,570,727
Ensembl chr18:56,537,437...56,570,727 		JBrowse link
G Tex19.2 testis expressed gene 19.2 multiple interactions ISO [cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of TEX19 mRNA; [cetrorelix co-treated with testosterone enanthate] results in decreased expression of TEX19 mRNA CTD PMID:18160741 NCBI chr10:106,878,083...106,880,671
Ensembl chr10:106,878,085...106,880,671 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression 		EXP 2-Methoxyestradiol inhibits the reaction [testosterone enanthate results in increased expression of TGFB1 protein] CTD PMID:30154949 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgoln2 trans-golgi network protein 2 affects expression ISO testosterone enanthate affects the expression of TGOLN2 mRNA CTD PMID:17440010 NCBI chr 4:106,221,503...106,229,360
Ensembl chr 4:106,221,509...106,229,262 		JBrowse link
G Thbs4 thrombospondin 4 affects expression ISO testosterone enanthate affects the expression of THBS4 mRNA CTD PMID:17440010 NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:25,718,219...25,761,369 		JBrowse link
G Thnsl1 threonine synthase-like 1 affects expression ISO testosterone enanthate affects the expression of THNSL1 mRNA CTD PMID:17440010 NCBI chr17:88,623,054...88,630,681
Ensembl chr17:88,614,606...88,641,871 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 affects expression ISO testosterone enanthate affects the expression of TIE mRNA CTD PMID:17440010 NCBI chr 5:137,285,408...137,305,047
Ensembl chr 5:137,285,408...137,304,981 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 affects expression ISO testosterone enanthate affects the expression of TIMP3 mRNA CTD PMID:17440010 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547