carbohydrate sulfate - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	carbohydrate sulfate	go back to main search page
Accession:	CHEBI:35724	browse the term
Synonyms:	related_synonym:	carbohydrate sulfates; carbohydrate sulphates

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Rat (1959 ) Mouse (2212 ) Human (1971 ) Chinchilla (0 ) Bonobo (0 ) Dog (0 ) Squirrel (0 ) Pig (12 ) Green Monkey (0) Naked Mole-rat (0 ) All
Genes (1959)

beta-D-glucosamine 6-sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acyl-CoA synthetase long-chain family member 1

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of ACSL1 mRNA

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023

G

arachidonate 5-lipoxygenase

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 mRNA]

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

CCAAT/enhancer binding protein alpha

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of CEBPA mRNA; glucosamine 6-O-sulfate results in decreased expression of CEBPA protein

NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of CHUK protein]

NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273

G

fatty acid binding protein 4

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

Fas cell surface death receptor

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

inhibitor of nuclear factor kappa B kinase subunit beta

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein]

NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911

G

interleukin 1 beta

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

leptin

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of LEP mRNA

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

lipase E, hormone sensitive type

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of LIPE mRNA

NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117

G

lipoprotein lipase

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of LPL mRNA

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107

G

mitogen activated protein kinase 1

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

nuclear factor kappa B subunit 1

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein]

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nitric oxide synthase 2

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

phospholipase A2 group 4A

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A protein]

NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641

G

perilipin 1

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of PLIN1 mRNA

NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206

G

peroxisome proliferator-activated receptor gamma

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of PPARG mRNA; glucosamine 6-O-sulfate results in decreased expression of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

prostaglandin-endoperoxide synthase 2

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

sterol regulatory element binding transcription factor 1

decreases expression

ISO

glucosamine 6-O-sulfate results in decreased expression of SREBF1 mRNA; glucosamine 6-O-sulfate results in decreased expression of SREBF1 protein

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

tumor necrosis factor

multiple interactions

ISO

glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions

ISO

Carrageenan results in increased phosphorylation of AKT1 protein
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

albumin

multiple interactions
decreases expression

EXP

caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of ALB protein]; Indomethacin inhibits the reaction [Carrageenan results in decreased expression of ALB protein]

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

annexin A1

affects response to substance
multiple interactions

ISO

ANXA1 protein affects the susceptibility to Carrageenan
ANXA1 protein affects the susceptibility to [Dexamethasone co-treated with Carrageenan]

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

amyloid P component, serum

increases expression

EXP

Carrageenan results in increased expression of APCS protein

NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824

G

catalase

multiple interactions
decreases activity

ISO
EXP

fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein]
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased activity of CAT protein]; Indomethacin inhibits the reaction [Carrageenan results in decreased activity of CAT protein]; procyanidin B2 inhibits the reaction [Carrageenan results in decreased activity of CAT protein]

PMID:26418808 PMID:28844677 PMID:34789018

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 2

multiple interactions
increases expression

ISO

5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of CCL2 protein]

PMID:12444156 PMID:20383154

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 3

multiple interactions
increases expression

ISO

5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of CCL3 protein]

PMID:12444156 PMID:20383154

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 5

increases expression
multiple interactions

ISO
EXP

Carrageenan results in increased expression of CCL5 protein
isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of CCL5 protein]

PMID:12444156 PMID:14654164

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

chymase 1

multiple interactions
increases expression

EXP

adelmidrol inhibits the reaction [Carrageenan results in increased expression of CMA1 protein]

NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133

G

C-reactive protein

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of CRP protein
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of CRP protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of CRP protein]

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

C-X-C motif chemokine ligand 2

multiple interactions
increases secretion
increases expression

EXP
ISO

IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of CXCL2 protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of CXCL2 protein]

PMID:12444156 PMID:14654164 PMID:21549112

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

increases expression

ISO

Carrageenan results in increased expression of CXCL1 protein

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

early growth response 1

increases expression
multiple interactions

ISO

Carrageenan results in increased expression of EGR1 protein
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Carrageenan results in increased expression of EGR1 protein]; EGR1 protein inhibits the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein]; NFKBIA protein inhibits the reaction [Carrageenan results in increased expression of EGR1 protein]

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

EXP

3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Flurbiprofen inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Flurbiprofen promotes the reaction [Urethane inhibits the reaction [Carrageenan results in increased expression of FOS protein]]; Urethane inhibits the reaction [Carrageenan results in increased expression of FOS protein]; Urethane inhibits the reaction [Flurbiprofen inhibits the reaction [Carrageenan results in increased expression of FOS protein]]

PMID:1327382 PMID:11164833

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

galanin and GMAP prepropeptide

decreases response to substance

ISO

GAL protein results in decreased susceptibility to Carrageenan

NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229

G

G protein-coupled receptor 132

increases expression

ISO

Carrageenan results in increased expression of GPR132 mRNA

NCBI chr 6:137,745,142...137,763,037
Ensembl chr 6:137,745,241...137,763,157

G

G protein-coupled receptor 4

increases expression

ISO

Carrageenan results in increased expression of GPR4 mRNA

NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:87,993,430...88,006,254

G

G-protein coupled receptor 65

increases expression

ISO

Carrageenan results in increased expression of GPR65 mRNA

NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:123,219,633...123,266,285

G

heme oxygenase 1

multiple interactions
decreases expression

EXP

caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of HMOX1 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in decreased expression of HMOX1 mRNA]; procyanidin B2 inhibits the reaction [Carrageenan results in decreased expression of HMOX1 protein]
Carrageenan results in decreased expression of HMOX1 mRNA; Carrageenan results in decreased expression of HMOX1 protein

PMID:28844677 PMID:34789018

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heat shock protein family A (Hsp70) member 1A

increases expression

EXP

Carrageenan results in increased expression of HSPA1A protein

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

intercellular adhesion molecule 1

multiple interactions
increases expression

EXP

caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of ICAM1 mRNA]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of ICAM1 mRNA]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of ICAM1 protein]
Carrageenan results in increased expression of ICAM1 mRNA; Carrageenan results in increased expression of ICAM1 protein

PMID:11181422 PMID:22330755 PMID:27803785 PMID:34789018

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

interleukin 10

increases secretion
multiple interactions
increases expression

EXP
ISO

Carrageenan results in increased secretion of IL10 protein
indole-3-guanylhydrazone hydrochloride promotes the reaction [Carrageenan results in increased secretion of IL10 protein]; Indomethacin promotes the reaction [Carrageenan results in increased secretion of IL10 protein]
Indomethacin inhibits the reaction [Carrageenan results in increased expression of IL10 mRNA]; procyanidin B2 inhibits the reaction [Carrageenan results in increased secretion of IL10 protein]; Thioctic Acid promotes the reaction [Carrageenan results in increased expression of IL10 mRNA]

PMID:11181422 PMID:19735303 PMID:28844677 PMID:29499192

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 1 alpha

multiple interactions
decreases expression

ISO

Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]; Dexamethasone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Dexamethasone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]; Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]; Naloxone inhibits the reaction [Carrageenan inhibits the reaction [Morphine results in decreased expression of IL1A protein]]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Carrageenan results in decreased expression of IL1A protein]]

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

increases secretion
increases expression
multiple interactions

ISO
EXP

Carrageenan results in increased secretion of IL1B protein
Carrageenan results in increased expression of IL1B mRNA; Carrageenan results in increased expression of IL1B protein
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; indole-3-guanylhydrazone hydrochloride inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; Indomethacin inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; budlein A inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of IL1B mRNA]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of IL1B protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of IL1B mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of IL1B protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased expression of IL1B protein]

PMID:11181422 PMID:16368644 PMID:17320857 PMID:20383154 PMID:21549112 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions
increases expression
increases secretion

ISO
EXP

5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of IL6 protein]
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Diclofenac inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of IL6 protein]; procyanidin B2 inhibits the reaction [Carrageenan results in increased secretion of IL6 protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased expression of IL6 protein]

PMID:11181422 PMID:20383154 PMID:22330755 PMID:23774260 PMID:24412305 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

kallikrein 1-related peptidase C10

multiple interactions
increases expression

EXP

procyanidin B2 inhibits the reaction [Carrageenan results in increased expression of KLK3 protein]

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

ISO

Carrageenan results in increased phosphorylation of MAPK1 protein
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 14

multiple interactions
increases expression

EXP

caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of MAPK14 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of MAPK14 mRNA]

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

ISO

fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

matrix metallopeptidase 9

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of MMP9 protein
adelmidrol inhibits the reaction [Carrageenan results in increased expression of MMP9 protein]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

myeloperoxidase

multiple interactions
increases activity
increases expression

EXP

adelmidrol inhibits the reaction [Carrageenan results in increased activity of MPO protein]; arvelexin analog inhibits the reaction [Carrageenan results in increased expression of MPO protein]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of MPO mRNA]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Diclofenac inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Ibuprofen inhibits the reaction [Carrageenan results in increased expression of MPO protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of MPO mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Carrageenan results in increased activity of MPO protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased activity of MPO protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased activity of MPO protein]
Carrageenan results in increased expression of MPO mRNA; Carrageenan results in increased expression of MPO protein

PMID:9890637 PMID:15860553 PMID:18429935 PMID:23872256 PMID:24412305 More...

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

metallothionein 1A

multiple interactions

ISO

[Methylnitrosourea co-treated with Carrageenan] results in increased expression of MT1 protein

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

NFE2 like bZIP transcription factor 2

affects localization
decreases expression
multiple interactions

EXP

Carrageenan affects the localization of NFE2L2 protein
Carrageenan results in decreased expression of NFE2L2 mRNA
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in decreased expression of NFE2L2 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in decreased expression of NFE2L2 mRNA]; procyanidin B2 inhibits the reaction [Carrageenan affects the localization of NFE2L2 protein]

PMID:28844677 PMID:34789018

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor kappa B subunit 1

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of NFKB1 mRNA
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of NFKB1 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of NFKB1 mRNA]

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

multiple interactions

ISO

NFKBIA protein inhibits the reaction [Carrageenan results in increased expression of EGR1 protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nerve growth factor

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of NGF protein
Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NGF protein]

NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834

G

nitric oxide synthase 2

multiple interactions
increases expression
increases activity

EXP
ISO

adelmidrol inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein]; Carrageenan promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of NOS2 mRNA]
fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]
Carrageenan results in increased activity of NOS2 protein
Carrageenan results in increased expression of NOS2 mRNA; Carrageenan results in increased expression of NOS2 protein

PMID:7542281 PMID:9890637 PMID:15860553 PMID:18429935 PMID:22330755 More...

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

NAD(P)H quinone dehydrogenase 1

decreases expression
multiple interactions

EXP

Carrageenan results in decreased expression of NQO1 protein
procyanidin B2 inhibits the reaction [Carrageenan results in decreased expression of NQO1 protein]

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

opioid receptor, mu 1

decreases expression

ISO

Carrageenan results in decreased expression of OPRM1 protein

NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756

G

purinergic receptor P2X 7

multiple interactions

EXP

[(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Carrageenan

NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193

G

platelet and endothelial cell adhesion molecule 1

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of PECAM1 protein
adelmidrol inhibits the reaction [Carrageenan results in increased expression of PECAM1 protein]

NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839

G

prostaglandin E synthase

multiple interactions
increases expression

EXP

arvelexin analog inhibits the reaction [Carrageenan results in increased expression of PTGES protein]

PMID:17258197 PMID:25451575

NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995

G

prostaglandin E synthase 2

multiple interactions
increases activity

EXP

2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid inhibits the reaction [[Carrageenan results in increased activity of PTGES2 protein] which results in increased chemical synthesis of Dinoprostone]; [Carrageenan results in increased activity of PTGES2 protein] which results in increased chemical synthesis of Dinoprostone

NCBI chr 3:36,088,246...36,095,430
Ensembl chr 3:36,088,246...36,097,694

G

prostaglandin-endoperoxide synthase 2

multiple interactions
increases expression

EXP
ISO

3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; dragon's blood inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; nimesulide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; Thioctic Acid inhibits the reaction [Carrageenan results in increased expression of PTGS2 mRNA]; triflusal inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
Carrageenan results in increased expression of PTGS2 mRNA; Carrageenan results in increased expression of PTGS2 protein

PMID:10101034 PMID:14654164 PMID:15860553 PMID:17258197 PMID:18814970 More...

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RELA proto-oncogene, NF-kB subunit

increases phosphorylation
increases expression
increases localization
multiple interactions

ISO
EXP

Carrageenan results in increased phosphorylation of RELA protein
Carrageenan results in increased expression of RELA protein
Carrageenan results in increased localization of RELA protein
caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of RELA protein]; IMMLG5521 inhibits the reaction [Carrageenan results in increased localization of RELA protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of RELA protein]

PMID:21549112 PMID:22561171 PMID:34789018

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

selectin P

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of SELP protein
imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of SELP protein]

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987

G

somatostatin receptor 4

decreases response to substance

ISO

SSTR4 results in decreased susceptibility to Carrageenan

NCBI chr 3:156,307,992...156,309,855
Ensembl chr 3:156,307,093...156,550,348

G

signal transducer and activator of transcription 3

multiple interactions
increases expression

EXP

caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of STAT3 mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of STAT3 mRNA]

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

transforming growth factor, beta 1

increases secretion

ISO

Carrageenan results in increased secretion of TGFB1 protein

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

tight junction protein 1

multiple interactions

ISO

3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein]; Carrageenan results in decreased expression of and affects the localization of TJP1 protein; EGR1 protein inhibits the reaction [Carrageenan results in decreased expression of and affects the localization of TJP1 protein]

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

tumor necrosis factor

increases secretion
multiple interactions
increases expression

ISO
EXP

Carrageenan results in increased secretion of TNF protein
3-methylquercetin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; adelmidrol inhibits the reaction [Carrageenan results in increased expression of TNF protein]; budlein A inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of TNF mRNA]; caffeic acid phenethyl ester inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Carrageenan results in increased expression of TNF protein]; imisopasem manganese inhibits the reaction [Carrageenan results in increased expression of TNF protein]; IMMLG5521 inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of TNF mRNA]; Indomethacin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; isoquercitrin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; N-(2-hydroxybenzoyl)tyramine inhibits the reaction [Carrageenan results in increased expression of TNF protein]; procyanidin B2 inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Quercetin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Rutin inhibits the reaction [Carrageenan results in increased expression of TNF protein]; Thiazolidines analog inhibits the reaction [Carrageenan results in increased expression of TNF protein]
Carrageenan results in increased expression of TNF mRNA; Carrageenan results in increased expression of TNF protein
5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid inhibits the reaction [Carrageenan results in increased expression of TNF protein]; diaoxinxuekang inhibits the reaction [Carrageenan results in increased expression of TNF protein]; indole-3-guanylhydrazone hydrochloride inhibits the reaction [Carrageenan results in increased secretion of TNF protein]; Indomethacin inhibits the reaction [Carrageenan results in increased secretion of TNF protein]

PMID:11181422 PMID:12444156 PMID:14654164 PMID:16368644 PMID:17320857 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

vascular cell adhesion molecule 1

increases expression
multiple interactions

EXP

Carrageenan results in increased expression of VCAM1 mRNA
Dexamethasone inhibits the reaction [Carrageenan results in increased expression of VCAM1 mRNA]; Fluvoxamine inhibits the reaction [Carrageenan results in increased expression of VCAM1 mRNA]

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801

chondroitin sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylsulfatase B

decreases abundance

ISO

ARSB protein results in decreased abundance of Chondroitin Sulfates

NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:26,736,957...26,897,611

G

bradykinin receptor B2

multiple interactions

EXP

[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Chondroitin Sulfates

NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209

G

brain-derived neurotrophic factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

complement C3

increases cleavage

ISO

Chondroitin Sulfates analog results in increased cleavage of C3 protein

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C5

increases cleavage

ISO

Chondroitin Sulfates analog results in increased cleavage of C5 protein

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

caspase 3

multiple interactions

ISO

[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 7

multiple interactions

ISO

[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA]

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

catalase

multiple interactions

EXP

Chondroitin Sulfates inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]

PMID:12736501 PMID:15089041

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 2

affects binding

ISO

Chondroitin Sulfates binds to CCL2 protein

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

cathepsin B

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL11 protein]; Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL9 protein]; Chondroitin Sulfates promotes the reaction [CTSB protein results in increased cleavage of benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide]

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cathepsin K

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSK protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide]; Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL2 protein]; Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL3 protein]

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cathepsin L

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSL protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates inhibits the reaction [CTSL protein results in increased degradation of CXCL11 protein]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of CXCL2 protein]

NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113

G

cathepsin S

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSS protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of benzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of CXCL2 protein]

NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440

G

C-X-C motif chemokine ligand 1

multiple interactions

ISO

Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of CXCL1 protein]

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates inhibits the reaction [CTSK protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates inhibits the reaction [CTSL protein results in increased degradation of CXCL10 protein]; Chondroitin Sulfates inhibits the reaction [CTSS protein results in increased degradation of CXCL10 protein]

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 11

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL11 protein]; Chondroitin Sulfates inhibits the reaction [CTSL protein results in increased degradation of CXCL11 protein]

NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567

G

C-X-C motif chemokine ligand 2

multiple interactions

ISO

Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL2 protein]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of CXCL2 protein]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of CXCL2 protein]

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

multiple interactions

ISO

Chondroitin Sulfates promotes the reaction [CTSK protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSL protein results in increased cleavage of CXCL1 protein]; Chondroitin Sulfates promotes the reaction [CTSS protein results in increased cleavage of CXCL1 protein]

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

C-X-C motif chemokine ligand 9

multiple interactions

ISO

Chondroitin Sulfates inhibits the reaction [CTSB protein results in increased degradation of CXCL9 protein]

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

coagulation factor XII

increases activity

ISO

Chondroitin Sulfates analog results in increased activity of F12 protein

NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664

G

fibroblast growth factor 10

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein; Chondroitin Sulfates analog binds to FGF10 protein

PMID:12221095 PMID:15385557

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibroblast growth factor 16

affects binding

EXP

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF16 protein; Chondroitin Sulfates analog binds to FGF16 protein

PMID:12221095 PMID:15385557

NCBI chr X:74,882,863...74,893,598
Ensembl chr X:74,882,995...74,944,246

G

fibroblast growth factor 18

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein; Chondroitin Sulfates analog binds to FGF18 protein

PMID:12221095 PMID:15385557

NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933

G

fibroblast growth factor 2

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein; Chondroitin Sulfates analog binds to FGF2 protein

PMID:12221095 PMID:15385557

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 23

increases activity

ISO

Chondroitin Sulfates analog results in increased activity of FGF23 protein

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991

G

glial cell derived neurotrophic factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to GDNF protein

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

heparin-binding EGF-like growth factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to HBEGF protein; Chondroitin Sulfates analog binds to HBEGF protein

PMID:12221095 PMID:15385557

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

interleukin 1 beta

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

inter-alpha trypsin inhibitor, heavy chain 1

multiple interactions

ISO

TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Chondroitin Sulfates]

NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853

G

kallikrein B1

increases activity

ISO

Chondroitin Sulfates analog results in increased activity of KLKB1 protein

NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339

G

midkine

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein; Chondroitin Sulfates analog binds to MDK protein

PMID:12221095 PMID:15385557

NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743

G

matrix metallopeptidase 3

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826

G

myeloperoxidase

multiple interactions

EXP

[Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

nuclear factor kappa B subunit 1

multiple interactions

ISO

[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein]

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

multiple interactions

ISO

[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nitric oxide synthase 2

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

platelet derived growth factor subunit B

multiple interactions

ISO

Chondroitin Sulfates promotes the reaction [PDGFB protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]; Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGFB protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]]

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343

G

platelet derived growth factor receptor beta

multiple interactions

ISO

Chondroitin Sulfates promotes the reaction [PDGFB protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]; Genistein inhibits the reaction [Chondroitin Sulfates promotes the reaction [PDGFB protein results in increased phosphorylation of and results in increased activity of PDGFRB protein]]

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

prostaglandin E synthase

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein

NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995

G

prostaglandin-endoperoxide synthase 2

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

pleiotrophin

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein; Chondroitin Sulfates analog binds to PTN protein

PMID:12221095 PMID:15385557

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

protein tyrosine phosphatase, non-receptor type 11

affects binding

ISO

PTPN11 protein binds to Chondroitin Sulfates

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

[Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

TIMP metallopeptidase inhibitor 3

multiple interactions

ISO

[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

tumor necrosis factor

multiple interactions

EXP
ISO

[Chondroitin Sulfates co-treated with Hyaluronic Acid] inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF

PMID:14697411 PMID:20110869

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF alpha induced protein 6

multiple interactions

ISO

TNFAIP6 protein promotes the reaction [ITIH1 protein binds to Chondroitin Sulfates]

NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796

G

TNF receptor superfamily member 11B

multiple interactions
increases expression

ISO

[Chondroitin Sulfates co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein
Chondroitin Sulfates results in increased expression of TNFRSF11B protein

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF superfamily member 11

multiple interactions
decreases expression

ISO

[Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA]
Chondroitin Sulfates results in decreased expression of TNFSF11 mRNA

NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479

G

vascular endothelial growth factor A

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to VEGFA protein

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

dermatan sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

brain-derived neurotrophic factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to BDNF protein

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

coagulation factor II, thrombin

multiple interactions

ISO

[Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246

G

fibroblast growth factor 10

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF10 protein

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibroblast growth factor 16

affects binding

EXP

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF16 protein

NCBI chr X:74,882,863...74,893,598
Ensembl chr X:74,882,995...74,944,246

G

fibroblast growth factor 18

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF18 protein

NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933

G

fibroblast growth factor 2

affects binding
increases activity

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to FGF2 protein
Dermatan Sulfate analog results in increased activity of FGF2 protein

PMID:15385557 PMID:15563459

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 23

increases activity

ISO

Dermatan Sulfate analog results in increased activity of FGF23 protein

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991

G

fibroblast growth factor 7

increases activity

ISO

Dermatan Sulfate analog results in increased activity of FGF7 protein

NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328

G

glial cell derived neurotrophic factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to GDNF protein

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

heparin-binding EGF-like growth factor

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to HBEGF protein

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

midkine

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to MDK protein

NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743

G

platelet derived growth factor receptor alpha

decreases expression

ISO

Dermatan Sulfate results in decreased expression of PDGFRA mRNA

NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516

G

platelet derived growth factor receptor beta

decreases expression

ISO

Dermatan Sulfate results in decreased expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

pleiotrophin

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to PTN protein

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

serpin family D member 1

multiple interactions

ISO

[Dermatan Sulfate co-treated with SERPIND1 protein] results in decreased activity of F2 protein

NCBI chr11:97,168,753...97,179,830
Ensembl chr11:97,168,754...97,179,755

G

vascular endothelial growth factor A

affects binding

ISO

[Chondroitin Sulfates binds to Dermatan Sulfate] which binds to VEGFA protein

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

dextran sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alanyl-tRNA synthetase domain containing 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of AARSD1 protein]

NCBI chr10:86,840,874...86,854,077
Ensembl chr10:86,840,874...86,849,734

G

4-aminobutyrate aminotransferase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABAT mRNA

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ABCA1 mRNA

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473

G

ATP binding cassette subfamily B member 11

decreases expression

ISO

Dextran Sulfate results in decreased expression of ABCB11 mRNA; Dextran Sulfate results in decreased expression of ABCB11 protein

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP binding cassette subfamily B member 1A

multiple interactions
decreases expression
increases response to substance

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCB1A mRNA; ABCB1A protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
Dextran Sulfate results in decreased expression of ABCB1A mRNA
ABCB1A gene mutant form results in increased susceptibility to Dextran Sulfate

PMID:29950665 PMID:30102254 PMID:30701287 PMID:35093514

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP-binding cassette, sub-family B member 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCB1B mRNA; ABCB1B protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]

PMID:29950665 PMID:30701287

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567

G

ATP binding cassette subfamily B member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCB4 mRNA

NCBI chr 4:26,106,895...26,164,440

G

ATP binding cassette subfamily B member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCB6 mRNA

NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526

G

ATP binding cassette subfamily C member 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCC10 mRNA

NCBI chr 9:22,154,811...22,174,743
Ensembl chr 9:22,154,804...22,174,743

G

ATP binding cassette subfamily C member 2

decreases expression
multiple interactions
affects response to substance

ISO

Dextran Sulfate results in decreased expression of ABCC2 mRNA; Dextran Sulfate results in decreased expression of ABCC2 protein
ABCC2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
ABCC2 protein affects the susceptibility to Dextran Sulfate

PMID:27580383 PMID:30701287

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

ATP binding cassette subfamily C member 3

decreases expression
affects response to substance
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ABCC3 mRNA; Dextran Sulfate results in decreased expression of ABCC3 protein
ABCC3 protein affects the susceptibility to Dextran Sulfate
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCC3 mRNA; ABCC3 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]

PMID:27580383 PMID:29950665 PMID:30701287 PMID:38844255

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494

G

ATP binding cassette subfamily C member 4

multiple interactions
decreases expression

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of ABCC4 mRNA; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ABCC4 mRNA
Dextran Sulfate results in decreased expression of ABCC4 mRNA; Dextran Sulfate results in decreased expression of ABCC4 protein

PMID:26271895 PMID:27580383 PMID:29950665

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily C member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCC5 mRNA

NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655

G

ATP binding cassette subfamily C member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCC6 mRNA

NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895

G

ATP binding cassette subfamily C member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ABCC9 mRNA

NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348

G

ATP binding cassette subfamily F member 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ABCF2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ABCF2 protein]

NCBI chr 4:10,594,802...10,607,620
Ensembl chr 4:11,487,395...11,500,053

G

ATP binding cassette subfamily G member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ABCG1 mRNA

NCBI chr20:9,128,056...9,184,312
Ensembl chr20:9,127,803...9,186,563

G

ATP binding cassette subfamily G member 2

multiple interactions
decreases expression
affects response to substance

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ABCG2 mRNA; ABCG2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]
Dextran Sulfate results in decreased expression of ABCG2 mRNA
Rifampin promotes the reaction [Dextran Sulfate results in decreased expression of ABCG2 mRNA]
Dextran Sulfate results in decreased expression of ABCG2 mRNA; Dextran Sulfate results in decreased expression of ABCG2 protein
ABCG2 protein affects the susceptibility to Dextran Sulfate

PMID:29950665 PMID:30701287 PMID:38423481 PMID:38844255

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

abl-interactor 1

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ABI1 protein]

NCBI chr17:90,006,917...90,088,002
Ensembl chr17:90,006,925...90,087,827

G

abraxas 2, BRISC complex subunit

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ABRAXAS2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ABRAXAS2 protein]

NCBI chr 1:197,077,177...197,102,753
Ensembl chr 1:197,077,158...197,102,757

G

ankyrin repeat and BTB domain containing 1

multiple interactions
affects response to substance

ISO

[ABTB1 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein

NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:122,856,564...122,862,789

G

acetyl-CoA acyltransferase 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACAA1A mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241

G

acetyl-Coenzyme A acyltransferase 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACAA1B mRNA

NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569

G

acetyl-CoA acyltransferase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACAA2 mRNA

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420

G

acetyl-CoA carboxylase alpha

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ACACA protein]

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acyl-CoA dehydrogenase short chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACADS mRNA

NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103

G

acyl-CoA dehydrogenase, short/branched chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACADSB mRNA

NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ACAP2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ACAP2 protein]

NCBI chr11:83,043,442...83,159,105
Ensembl chr11:83,043,511...83,159,107

G

angiotensin I converting enzyme

multiple interactions
increases abundance

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACE mRNA
dextran sodium sulfate increases abundance of Ace protein in small and large intestine extracellular space

CTD
RGD

PMID:29950665 PMID:26401072

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

acetylcholinesterase

multiple interactions
decreases activity

ISO

[Chlorpyrifos co-treated with Dextran Sulfate] results in decreased activity of ACHE protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACHE mRNA
Dextran Sulfate results in decreased activity of ACHE protein

PMID:29950665 PMID:31226429 PMID:31807802

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410

G

atypical chemokine receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACKR1 mRNA

NCBI chr13:88,314,735...88,316,354
Ensembl chr13:88,293,188...88,317,807

G

atypical chemokine receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACKR2 mRNA

NCBI chr 8:130,438,703...130,451,106
Ensembl chr 8:130,384,559...130,464,393

G

atypical chemokine receptor 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACKR3 mRNA

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

atypical chemokine receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACKR4 mRNA

NCBI chr 8:113,595,325...113,599,762
Ensembl chr 8:113,595,293...113,602,372

G

acid phosphatase 6, lysophosphatidic

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ACP6 protein]

NCBI chr 2:187,400,786...187,421,877
Ensembl chr 2:187,349,186...187,422,743

G

acyl-CoA synthetase bubblegum family member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACSBG2 mRNA

NCBI chr 9:1,770,971...1,802,635
Ensembl chr 9:1,770,972...1,801,655

G

acyl-CoA synthetase medium-chain family member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACSM1 mRNA

NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217

G

acyl-CoA synthetase medium-chain family member 3

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ACSM3 protein
Dextran Sulfate results in increased expression of ACSM3 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ACSM3 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ACSM3 protein]

PMID:32272095 PMID:35362542

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437

G

acyl-CoA synthetase short-chain family member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACSS1 mRNA

NCBI chr 3:159,910,809...159,960,748
Ensembl chr 3:159,910,809...159,960,748

G

acyl-CoA synthetase short-chain family member 2

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ACSS2 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ACSS2 protein]

PMID:29950665 PMID:35362542

NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830

G

actin-like 6A

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ACTL6A protein]

NCBI chr 2:117,413,206...117,436,758
Ensembl chr 2:117,418,601...117,436,754

G

actinin, alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACTN1 mRNA

NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172

G

actinin alpha 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACTN2 mRNA

NCBI chr17:62,835,055...62,902,331
Ensembl chr17:62,812,988...62,903,552

G

actin related protein 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of ACTR2 protein

NCBI chr14:98,500,119...98,535,092
Ensembl chr14:98,500,138...98,541,998

G

actin related protein 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of ACTR3 protein

NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711

G

activin A receptor type 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ACVR1 mRNA

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884

G

aminoacylase 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of ACY1 protein

NCBI chr 8:115,951,068...115,956,471
Ensembl chr 8:115,951,068...115,956,405

G

adenosine deaminase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ADA protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ADA protein]

NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293

G

ADAM metallopeptidase domain 10

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ADAM10 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ADAM10 protein]

NCBI chr 8:80,226,862...80,358,728
Ensembl chr 8:80,226,674...80,361,600

G

ADAM metallopeptidase domain 17

multiple interactions
increases expression
affects response to substance

ISO

ADAM17 protein affects the reaction [Dextran Sulfate results in decreased expression of SIRT1 mRNA]; ADAM17 protein affects the reaction [Dextran Sulfate results in decreased expression of TIMP3 mRNA]; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IFNG protein]; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL17A protein]; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL1B protein]; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 protein]; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of TNF protein]; resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of ADAM17 mRNA]
ADAM17 protein affects the susceptibility to Dextran Sulfate

NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS1 mRNA

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390

G

ADAM metallopeptidase with thrombospondin type 1 motif, 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS14 mRNA

NCBI chr20:29,685,876...29,762,685
Ensembl chr20:29,685,876...29,762,682

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS2 mRNA

NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483

G

ADAM metallopeptidase with thrombospondin type 1 motif, 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS4 mRNA

NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADAMTS5 mRNA

NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516

G

adenylate cyclase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADCY2 mRNA

NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:36,204,054...36,650,645

G

adenylate cyclase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADCY4 mRNA

NCBI chr15:33,236,201...33,252,070
Ensembl chr15:33,236,208...33,252,026

G

adenylate cyclase 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ADCY6 mRNA

NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770

G

adenylate cyclase 7

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADCY7 mRNA
Dextran Sulfate results in decreased expression of ADCY7 mRNA

PMID:29950665 PMID:35093514

NCBI chr19:34,913,154...34,972,366
Ensembl chr19:34,914,322...34,936,743

G

adenylate cyclase activating polypeptide 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADCYAP1 mRNA

NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383

G

ADCYAP receptor type I

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ADCYAP1R1 mRNA

NCBI chr 4:85,924,171...85,972,973
Ensembl chr 4:85,924,100...85,972,973

G

adhesion G protein-coupled receptor A2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADGRA2 mRNA

NCBI chr16:71,635,814...71,674,275
Ensembl chr16:71,636,164...71,674,154

G

adhesion G protein-coupled receptor B1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ADGRB1 mRNA

NCBI chr 7:108,293,681...108,365,892
Ensembl chr 7:108,293,818...108,365,870

G

adhesion G protein-coupled receptor E1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ADGRE1 protein
flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of ADGRE1 protein]

NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959

G

adhesion G protein-coupled receptor E5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADGRE5 mRNA

NCBI chr19:41,302,687...41,332,183
Ensembl chr19:41,303,213...41,324,641

G

adhesion G protein-coupled receptor F1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADGRF1 mRNA

NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:25,147,588...25,208,916

G

adhesion G protein-coupled receptor F5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADGRF5 mRNA

NCBI chr 9:25,014,861...25,128,045
Ensembl chr 9:25,018,277...25,121,237

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADH1 mRNA

NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291

G

alcohol dehydrogenase 5 (class III), chi polypeptide

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ADH5 mRNA

NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232

G

adrenomedullin

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADM mRNA
Dextran Sulfate results in increased expression of ADM mRNA

PMID:29950665 PMID:35093514

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371

G

adenosine A2a receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADORA2A mRNA

NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802

G

adenosine A2B receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of ADORA2B mRNA

NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091

G

adenosine A3 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADORA3 mRNA

NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686

G

adrenoceptor alpha 2A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ADRA2A mRNA

NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871

G

adrenoceptor beta 2

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of ADRB2 mRNA; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ADRB2 mRNA

PMID:26271895 PMID:29950665

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

angiotensinogen

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AGT mRNA
Dextran Sulfate results in decreased expression of AGT mRNA

PMID:29950665 PMID:35093514

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

AHNAK nucleoprotein

decreases expression

ISO

Dextran Sulfate results in decreased expression of AHNAK mRNA

NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675

G

aryl hydrocarbon receptor

multiple interactions
increases response to substance

ISO

AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of CXCL1 mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of CXCL2 mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of LCN2 mRNA]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]
AHR gene mutant form results in increased susceptibility to Dextran Sulfate

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

alpha hemoglobin stabilizing protein

decreases expression

ISO

Dextran Sulfate results in decreased expression of AHSP protein

NCBI chr 1:192,310,306...192,315,943
Ensembl chr 1:192,310,244...192,315,942

G

aryl-hydrocarbon receptor-interacting protein

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of AIP protein]

NCBI chr 1:210,837,473...210,848,691
Ensembl chr 1:210,836,755...210,848,634

G

adenylate kinase 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of AK1 protein
[Dextran Sulfate co-treated with bisphenol A] results in increased expression of AK1 protein

NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757

G

A-kinase anchoring protein 12

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AKAP12 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of AKAP12 protein]

PMID:29950665 PMID:35362542

NCBI chr 1:43,135,515...43,225,245
Ensembl chr 1:43,199,008...43,225,557

G

A-kinase anchoring protein 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AKAP5 mRNA

NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620

G

A-kinase anchoring protein 8

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of AKAP8 protein]

NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900

G

aldo-keto reductase family 1 member B1

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of AKR1B1 protein
Dextran Sulfate results in increased expression of AKR1B1 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AKR1B1 mRNA

PMID:29950665 PMID:35093514 PMID:35999755

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1, member C3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 mRNA

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

AKT serine/threonine kinase 1

multiple interactions

ISO
EXP

[APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein]
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of AKT1 protein]; Dextran Sulfate results in increased expression of and results in increased phosphorylation of AKT1 protein; palmatine inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of AKT1 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of AKT1 protein]

PMID:26262998 PMID:36806191

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

albumin

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of ALB protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALB mRNA

PMID:29950665 PMID:35999755

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ALDH1A1 mRNA

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500

G

aldehyde dehydrogenase 1 family, member B1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ALDH1B1 mRNA

NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365

G

aldehyde dehydrogenase 2 family member

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ALDH2 mRNA

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

aldehyde dehydrogenase 3 family, member A2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648

G

aldehyde dehydrogenase 7 family, member A1

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ALDH7A1 protein]

NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467

G

aldolase, fructose-bisphosphate C

decreases expression
multiple interactions
increases expression

ISO

Dextran Sulfate results in decreased expression of ALDOA protein; Dextran Sulfate results in decreased expression of ALDOC mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ALDOC protein]

PMID:35093514 PMID:35362542 PMID:35999755

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133

G

arachidonate 12-lipoxygenase, 12S type

decreases expression

ISO

Dextran Sulfate results in decreased expression of ALOX12 protein

NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199

G

arachidonate 12-lipoxygenase, 12R type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALOX12B mRNA

NCBI chr10:54,361,898...54,373,776
Ensembl chr10:54,361,898...54,373,776

G

arachidonate 5-lipoxygenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALOX5 mRNA

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

arachidonate 5-lipoxygenase activating protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALOX5AP mRNA

NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038

G

alkaline phosphatase, biomineralization associated

multiple interactions
increases activity

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALPL mRNA
Dextran Sulfate results in increased activity of ALPL protein

PMID:29950665 PMID:30489199

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

adenosine monophosphate deaminase 3

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of AMPD3 protein]

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608

G

angiopoietin 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ANGPT4 mRNA

NCBI chr 3:160,880,539...160,913,923
Ensembl chr 3:160,880,728...160,913,921

G

angiopoietin-like 4

increases expression

ISO

Dextran Sulfate results in increased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681

G

anoctamin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ANO1 mRNA

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

anoctamin 10

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ANO10 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ANO10 protein]

PMID:29950665 PMID:35362542

NCBI chr 8:130,719,177...130,838,243
Ensembl chr 8:130,718,755...130,877,636

G

anoctamin 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ANO6 mRNA

NCBI chr 7:128,812,842...128,992,805
Ensembl chr 7:128,813,068...128,992,799

G

anoctamin 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ANO7 mRNA

NCBI chr 9:101,364,915...101,392,711
Ensembl chr 9:101,364,842...101,394,173

G

anoctamin 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ANO9 mRNA

NCBI chr 1:205,638,571...205,659,780
Ensembl chr 1:205,638,572...205,659,489

G

annexin A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ANXA1 mRNA

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ANXA4 mRNA

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513

G

adaptor related protein complex 1 subunit mu 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AP1M1 mRNA

NCBI chr16:17,620,910...17,636,431
Ensembl chr16:17,616,187...17,636,462

G

adaptor related protein complex 1 subunit sigma 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of AP1S1 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of AP1S1 protein]

NCBI chr12:25,261,958...25,272,483
Ensembl chr12:25,262,036...25,272,483

G

adaptor related protein complex 3 subunit mu 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of AP3M1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of AP3M1 protein]

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,295,444...3,313,104

G

APC regulator of WNT signaling pathway

affects response to substance
multiple interactions

ISO

APC affects the susceptibility to Dextran Sulfate; APC protein affects the susceptibility to Dextran Sulfate
[APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein; [APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form; [APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein; PDE4B protein affects the reaction [APC protein affects the susceptibility to Dextran Sulfate]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased phosphorylation of AKT1 protein]

PMID:16049979 PMID:26262998 PMID:30188895

NCBI chr18:26,138,382...26,196,021
Ensembl chr18:26,102,679...26,197,022

G

amyloid P component, serum

increases expression

ISO

Dextran Sulfate results in increased expression of APCS protein

NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824

G

apelin

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of APLN mRNA
Dextran Sulfate results in decreased expression of APLN mRNA

PMID:29950665 PMID:35093514

NCBI chr X:132,058,739...132,091,518
Ensembl chr X:132,081,759...132,091,246

G

apolipoprotein A2

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of APOA2 protein

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410

G

apolipoprotein A4

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of APOA4 protein
[Dextran Sulfate co-treated with bisphenol A] results in increased expression of APOA4 protein; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of APOA4 protein]

PMID:32272095 PMID:35999755

NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164

G

apolipoprotein B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of APOB mRNA

NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814

G

apolipoprotein C2

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of APOC2 protein

NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438

G

apolipoprotein E

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of APOE protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of APOE protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of APOE protein]

PMID:32272095 PMID:35362542

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

amyloid beta precursor protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of APP mRNA

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of APPL2 protein]

NCBI chr 7:22,019,480...22,072,386
Ensembl chr 7:22,022,963...22,072,385

G

aquaporin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AQP1 mRNA

NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504

G

aquaporin 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AQP11 mRNA

NCBI chr 1:161,457,752...161,467,918
Ensembl chr 1:161,457,754...161,467,945

G

aquaporin 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AQP2 mRNA

NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319

G

aquaporin 3 (Gill blood group)

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685

G

aquaporin 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AQP8 mRNA

NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242

G

aquaporin 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AQP9 mRNA

NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240

G

androgen receptor

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AR mRNA
Dextran Sulfate results in increased expression of AR mRNA

PMID:27920257 PMID:29950665

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

ARF GTPase 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARF3 protein

NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:131,750,672...131,770,123

G

ARF GTPase activating protein 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ARFGAP2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ARFGAP2 protein]

NCBI chr 3:97,692,105...97,704,246
Ensembl chr 3:97,692,110...97,704,247

G

arginase 1

multiple interactions
decreases expression

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 protein; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARG1 protein]
Dextran Sulfate results in decreased expression of ARG1 mRNA; Dextran Sulfate results in decreased expression of ARG1 protein

PMID:25026504 PMID:38164749

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

Rho GTPase activating protein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARHGAP1 protein

NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154

G

Rho GTPase activating protein 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGAP15 mRNA

NCBI chr 3:48,382,945...49,002,213
Ensembl chr 3:48,382,904...49,011,378

G

Rho GTPase activating protein 20

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARHGAP20 mRNA

NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:60,970,475...61,055,198

G

Rho GTPase activating protein 25

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGAP25 mRNA

NCBI chr 4:121,454,151...121,532,293
Ensembl chr 4:121,454,151...121,552,913

G

Rho GTPase activating protein 40

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARHGAP40 mRNA

NCBI chr 3:147,165,781...147,206,552
Ensembl chr 3:167,585,665...167,626,532

G

Rho GDP dissociation inhibitor alpha

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARHGDIA protein

NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347

G

Rho GDP dissociation inhibitor beta

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ARHGDIB mRNA
Dextran Sulfate results in decreased expression of ARHGDIB protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGDIB mRNA

PMID:23894361 PMID:29950665 PMID:35999755

NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068

G

Rho guanine nucleotide exchange factor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGEF1 mRNA

NCBI chr 1:89,626,884...89,648,823
Ensembl chr 1:89,628,266...89,649,067

G

Rho guanine nucleotide exchange factor 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ARHGEF12 mRNA

NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376

G

Rac/Cdc42 guanine nucleotide exchange factor 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGEF6 mRNA

NCBI chr X:140,182,734...140,302,812
Ensembl chr X:140,182,734...140,344,458

G

ARF like GTPase 3

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of ARL3 mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ARL3 protein]

PMID:35093514 PMID:35362542

NCBI chr 1:255,342,078...255,388,087
Ensembl chr 1:255,342,076...255,388,279

G

ARF like GTPase 9

increases expression

ISO

Dextran Sulfate results in increased expression of ARL9 mRNA

NCBI chr14:31,157,573...31,166,803
Ensembl chr14:31,511,330...31,520,988

G

actin related protein 2/3 complex, subunit 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARPC2 protein

NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:83,269,932...83,305,409

G

actin related protein 2/3 complex, subunit 3

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of ARPC3 protein
Dextran Sulfate results in decreased expression of ARPC3 protein

NCBI chr12:39,833,569...39,847,436
Ensembl chr12:39,833,569...39,847,436

G

actin related protein 2/3 complex, subunit 4

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARPC4 protein

NCBI chr 4:148,077,799...148,088,427
Ensembl chr 4:148,077,240...148,088,428

G

actin related protein 2/3 complex, subunit 5

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ARPC5 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ARPC5 protein]

NCBI chr13:67,454,379...67,463,288
Ensembl chr13:67,437,027...67,463,283

G

arrestin, beta 2

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of ARRB2 mRNA

NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487

G

arylsulfatase B

decreases expression

ISO

Dextran Sulfate results in decreased expression of ARSB mRNA

NCBI chr 2:26,736,395...26,895,682
Ensembl chr 2:26,736,957...26,897,611

G

ankyrin repeat and SOCS box-containing 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ASB2 mRNA

NCBI chr 6:128,239,550...128,275,833
Ensembl chr 6:128,239,552...128,266,321

G

acid sensing ion channel subunit family member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ASIC4 mRNA

NCBI chr 9:84,389,610...84,411,545
Ensembl chr 9:84,390,104...84,411,538

G

argininosuccinate synthase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of ASS1 mRNA

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627

G

autophagy related 5

multiple interactions
increases expression

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]; [Dietary Fats co-treated with Dextran Sulfate] results in decreased expression of ATG5 mRNA; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG5 mRNA]]; obeticholic acid inhibits the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in decreased expression of ATG5 mRNA]

PMID:27611972 PMID:31676321 PMID:35439472

NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821

G

autophagy related 7

multiple interactions
increases expression

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]; 6-formylindolo(3,2-b)carbazole promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]; alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]; Leucine inhibits the reaction [alpinetin promotes the reaction [Dextran Sulfate results in increased expression of ATG7 mRNA]]

NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319

G

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

decreases expression

ISO

Dextran Sulfate results in decreased expression of ATIC protein

NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756

G

ATPase phospholipid transporting 10A (putative)

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP10A mRNA

NCBI chr 1:118,692,456...118,866,117
Ensembl chr 1:118,692,478...118,866,114

G

ATPase phospholipid transporting 11B (putative)

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP11B mRNA

NCBI chr 2:118,585,348...118,691,076
Ensembl chr 2:120,513,552...120,619,249

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP12A mRNA

NCBI chr15:34,559,209...34,583,866
Ensembl chr15:34,559,209...34,583,866

G

ATPase Na+/K+ transporting subunit alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP1A1 mRNA

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:191,709,311...191,737,425

G

ATPase Na+/K+ transporting subunit alpha 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP1A3 mRNA

NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:89,700,649...89,729,825

G

ATPase Na+/K+ transporting subunit alpha 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP1A4 mRNA

NCBI chr13:87,216,139...87,252,155
Ensembl chr13:87,216,139...87,251,724

G

ATPase Na+/K+ transporting subunit beta 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP1B1 mRNA

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549

G

ATPase Na+/K+ transporting subunit beta 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP1B3 mRNA

NCBI chr 8:105,789,824...105,821,151
Ensembl chr 8:65,253,361...65,254,304
Ensembl chr 8:65,253,361...65,254,304

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP2A1 mRNA

NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:190,457,198...190,475,423

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP2A3 mRNA

NCBI chr10:58,079,710...58,111,279
Ensembl chr10:58,079,852...58,111,278

G

ATPase plasma membrane Ca2+ transporting 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP2B1 mRNA

NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904

G

ATPase secretory pathway Ca2+ transporting 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of ATP2C2 mRNA

NCBI chr19:64,662,729...64,719,998
Ensembl chr19:64,662,715...64,719,996

G

ATPase H+/K+ transporting subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP4B mRNA

NCBI chr16:82,846,329...82,855,242
Ensembl chr16:82,846,329...82,855,242

G

ATP synthase membrane subunit f

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ATP5MF protein]

NCBI chr12:14,535,435...14,542,007
Ensembl chr12:14,522,832...14,542,709

G

ATPase H+ transporting V0 subunit a2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP6V0A2 mRNA

NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860

G

ATPase H+ transporting V0 subunit a4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP6V0A4 mRNA

NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092

G

ATPase H+ transporting V0 subunit C

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ATP6V0C protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ATP6V0C protein]

NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245

G

ATPase H+ transporting V0 subunit D1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ATP6V0D1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ATP6V0D1 protein]

NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395

G

ATPase H+ transporting V0 subunit D2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP6V0D2 mRNA

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245

G

ATPase H+ transporting V1 subunit E2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP6V1E2 mRNA

NCBI chr 6:13,417,046...13,425,628
Ensembl chr 6:13,404,848...13,456,037

G

ATPase H+ transporting V1 subunit F

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of ATP6V1F mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ATP6V1F protein]

PMID:35093514 PMID:35362542

NCBI chr 4:59,033,020...59,035,980

G

ATPase H+ transporting V1 subunit G3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP6V1G3 mRNA

NCBI chr13:52,351,787...52,376,784
Ensembl chr13:52,351,801...52,375,594

G

ATPase copper transporting alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP7A mRNA

NCBI chr X:75,159,635...75,267,094
Ensembl chr X:75,159,782...75,267,093

G

ATPase phospholipid transporting 8B1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ATP8B1 mRNA

NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027

G

ATPase phospholipid transporting 8B2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ATP8B2 mRNA

NCBI chr 2:175,378,514...175,402,265
Ensembl chr 2:177,676,208...177,699,575

G

arginine vasopressin receptor 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AVPR1A mRNA

NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837

G

arginine vasopressin receptor 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AVPR1B mRNA

NCBI chr13:45,598,116...45,611,680
Ensembl chr13:45,598,763...45,611,277

G

arginine vasopressin receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AVPR2 mRNA

NCBI chr X:156,785,009...156,787,477
Ensembl chr X:156,785,139...156,787,477

G

axin 2

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of AXIN2 mRNA; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of AXIN2 protein; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of AXIN2 mRNA]; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of AXIN2 protein]

NCBI chr10:94,393,379...94,426,579
Ensembl chr10:94,395,909...94,426,575

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of B3GNT3 mRNA

NCBI chr16:18,434,114...18,444,851
Ensembl chr16:18,435,378...18,444,738

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of B3GNT7 protein
Dextran Sulfate results in increased expression of B3GNT7 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of B3GNT7 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of B3GNT7 protein]

PMID:32272095 PMID:35362542

NCBI chr 9:94,404,197...94,408,148
Ensembl chr 9:94,404,135...94,408,147

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of B3GNT8 mRNA

NCBI chr 1:90,263,387...90,266,292
Ensembl chr 1:90,263,827...90,270,287

G

bile acid CoA:amino acid N-acyltransferase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BAAT mRNA

NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181

G

barrier to autointegration nuclear assembly factor 1

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of BANF1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of BANF1 protein]

PMID:32272095 PMID:35362542

NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552

G

B-cell scaffold protein with ankyrin repeats 1

increases expression

ISO

Dextran Sulfate results in increased expression of BANK1 mRNA

NCBI chr 2:227,203,998...227,474,008
Ensembl chr 2:227,203,998...227,474,037

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression

ISO

[RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased expression of BAX mRNA; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased expression of BAX protein; daphnetin inhibits the reaction [Dextran Sulfate results in increased expression of BAX protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased cleavage of BAX protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of BAX protein]

PMID:24146755 PMID:37209277 PMID:38583725

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

butyrylcholinesterase

multiple interactions
decreases activity

ISO

[Chlorpyrifos co-treated with Dextran Sulfate] results in decreased activity of BCHE protein
Dextran Sulfate results in decreased activity of BCHE protein

PMID:31226429 PMID:31807802

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BCL2 protein; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BCL2 protein]; Camptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BCL2 protein]; daphnetin inhibits the reaction [Dextran Sulfate results in decreased expression of BCL2 protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in decreased expression of BCL2 protein]; Plant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BCL2 protein]

PMID:25449198 PMID:37209277 PMID:38583725

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

BCL6, transcription repressor

multiple interactions

ISO

BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]]

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

BAF chromatin remodeling complex subunit BCL7C

increases expression

ISO

Dextran Sulfate results in increased expression of BCL7C mRNA

NCBI chr 1:191,703,432...191,754,751
Ensembl chr 1:191,691,089...191,754,641

G

bradykinin receptor B1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BDKRB1 mRNA

NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973

G

bradykinin receptor B2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BDKRB2 mRNA

NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209

G

beclin 1

multiple interactions
increases expression

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]; [Dextran Sulfate co-treated with 6-formylindolo(3,2-b)carbazole] results in increased expression of BECN1 protein; [Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein; [HU 308 co-treated with Dextran Sulfate] affects the expression of BECN1 protein; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein]; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of BECN1 protein]; Nicotine promotes the reaction [Dextran Sulfate results in increased expression of BECN1 protein]
dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in increased expression of BECN1 protein]]; Nicotine promotes the reaction [Dextran Sulfate results in increased expression of BECN1 protein]

PMID:27611972 PMID:31676321 PMID:31926917

NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002

G

bestrophin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BEST1 mRNA

NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974

G

biglycan

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BGN mRNA

NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799

G

bridging integrator 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of BIN2 protein

NCBI chr 7:133,620,782...133,647,019
Ensembl chr 7:133,620,140...133,647,218

G

baculoviral IAP repeat-containing 5

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]; Camptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]; Plant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

baculoviral IAP repeat-containing 6

decreases expression

ISO

Dextran Sulfate results in decreased expression of BIRC6 mRNA

NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:26,474,843...26,668,507

G

bone morphogenetic protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BMP1 mRNA

NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485

G

bone morphogenetic protein 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BMP10 mRNA

NCBI chr 4:121,423,936...121,439,094
Ensembl chr 4:121,429,199...121,435,728

G

bone morphogenetic protein 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BMP7 mRNA

NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137

G

bone morphogenetic protein receptor type 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BMPR1B mRNA

NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:233,211,525...233,544,311

G

bone morphogenetic protein receptor type 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BMPR2 mRNA

NCBI chr 9:68,685,942...68,801,353
Ensembl chr 9:68,685,988...68,801,350

G

BPI fold containing family A, member 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of BPIFA1 protein

NCBI chr 3:163,087,965...163,093,708
Ensembl chr 3:163,087,965...163,093,708

G

3'(2'), 5'-bisphosphate nucleotidase 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of BPNT2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of BPNT2 protein]

NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126

G

BRICK1 subunit of SCAR/WAVE actin nucleating complex

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of BRK1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of BRK1 protein]

NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:148,306,398...148,321,984

G

B-box and SPRY domain containing

increases expression

ISO

Dextran Sulfate results in increased expression of BSPRY mRNA

NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:80,942,979...80,988,154

G

bone marrow stromal cell antigen 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of BST1 mRNA

NCBI chr14:71,466,179...71,482,671
Ensembl chr14:71,466,180...71,482,647

G

basic transcription factor 3-like 4

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of BTF3L4 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of BTF3L4 protein]

NCBI chr 5:128,796,594...128,816,219
Ensembl chr 5:128,796,594...128,816,602

G

core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of C1GALT1 mRNA

NCBI chr 4:36,894,440...36,932,434
Ensembl chr 4:36,894,488...36,932,441

G

C1GALT1-specific chaperone 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of C1GALT1C1 mRNA

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

complement C1q A chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C1QA mRNA

NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732

G

complement C1q B chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C1QB mRNA

NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840

G

C1q and TNF related 6

decreases expression

ISO

Dextran Sulfate results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:111,958,348...111,964,948
Ensembl chr 7:111,958,350...111,966,871

G

complement C1s

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C1S1 mRNA

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736

G

complement C3

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of C3 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C3 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of C3 protein]

PMID:29950665 PMID:35362542 PMID:35999755

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C3a receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C3AR1 mRNA

NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323

G

complement C4B

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C4B mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of C4B protein]

PMID:29950665 PMID:32272095

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement component 4 binding protein, alpha

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of C4BPA protein

NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471

G

complement C5a receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of C5AR1 mRNA

NCBI chr 1:86,077,309...86,088,001

G

carbonic anhydrase 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CAR1 protein]

NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454

G

carbonic anhydrase 3

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of CA3 protein]

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

carbonic anhydrase 4

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CA4 protein]

NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916

G

calcium binding protein 39

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CAB39 mRNA

NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542

G

calcium voltage-gated channel subunit alpha1 F

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CACNA1F mRNA

NCBI chr X:17,539,992...17,568,308
Ensembl chr X:17,539,920...17,568,308

G

calcium voltage-gated channel subunit alpha1 S

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CACNA1S mRNA

NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903

G

calcitonin-related polypeptide alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CALCA mRNA

NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529

G

calcitonin-related polypeptide, beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CALCB mRNA

NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654

G

calmodulin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CALM1 mRNA

NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381

G

calmodulin 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CALM2 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of CALM2 protein

NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657

G

calreticulin

decreases expression

ISO

Dextran Sulfate results in decreased expression of CALR protein

NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236

G

calcium/calmodulin-dependent protein kinase II gamma

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CAMK2G mRNA

NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,553,294...3,612,310

G

calcium/calmodulin-dependent protein kinase IV

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CAMK4 mRNA

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

calcium/calmodulin-dependent protein kinase kinase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CAMKK1 mRNA

NCBI chr10:58,135,872...58,159,023
Ensembl chr10:58,135,915...58,159,010

G

cyclase associated actin cytoskeleton regulatory protein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CAP1 protein

NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470

G

calpain 13

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CAPN13 protein]

NCBI chr 6:27,823,664...27,918,676
Ensembl chr 6:27,823,517...27,918,665

G

capping actin protein of muscle Z-line subunit beta

decreases expression

ISO

Dextran Sulfate results in decreased expression of CAPZB protein

NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:156,650,432...156,818,619

G

carbonic anhydrase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CAR2 mRNA

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064

G

calcium/calmodulin dependent serine protein kinase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CASK protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CASK protein]

NCBI chr X:11,572,328...11,915,831
Ensembl chr X:11,572,636...11,911,948

G

caspase 1

multiple interactions
increases expression

ISO
EXP

3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein]; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of CASP1 protein; [HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Dextran Sulfate results in increased activity of and results in increased cleavage of CASP1 protein; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased activity of and results in increased cleavage of CASP1 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased activity of and results in increased cleavage of CASP1 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 protein]
celastrol inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide promotes the reaction [celastrol inhibits the reaction [Dextran Sulfate results in increased expression of CASP1 protein]]
Dextran Sulfate results in increased expression of CASP1 mRNA; Dextran Sulfate results in increased expression of CASP1 protein

PMID:27611972 PMID:30270565 PMID:32470352 PMID:34964214 PMID:36577154 More...

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 3

increases cleavage
increases activity
multiple interactions

ISO

Dextran Sulfate results in increased cleavage of CASP3 protein
Dextran Sulfate results in increased activity of CASP3 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CASP3 mRNA; alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; biochanin A inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; daphnetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased activity of CASP3 protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased activity of CASP3 protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased activity of CASP3 protein]

PMID:21989142 PMID:27920257 PMID:28421826 PMID:29950665 PMID:31676321 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 8

multiple interactions
decreases expression

ISO

dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in decreased expression of CASP8 protein]

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

catalase

decreases activity
increases activity
multiple interactions

ISO

Dextran Sulfate results in decreased activity of CAT protein
Dextran Sulfate results in increased activity of CAT protein
[Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased activity of CAT protein]; gingerol inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased activity of CAT protein]

PMID:27125760 PMID:28421826 PMID:30489199 PMID:31737179 PMID:34964214

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolae associated protein 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of CAVIN2 protein

NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024

G

carbonyl reductase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CBR1 protein

NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104

G

carbonyl reductase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CBR3 mRNA

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558

G

coiled-coil domain containing 12

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC12 mRNA

NCBI chr 8:119,513,007...119,564,802
Ensembl chr 8:119,514,094...119,564,802

G

coiled-coil domain containing 124

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC124 mRNA

NCBI chr16:18,600,737...18,606,556
Ensembl chr16:18,600,737...18,606,556

G

coiled-coil domain containing 13

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC13 mRNA

NCBI chr 8:121,455,202...121,507,487
Ensembl chr 8:130,335,204...130,377,096

G

coiled-coil domain containing 158

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CCDC158 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CCDC158 protein]

NCBI chr14:15,695,456...15,752,896
Ensembl chr14:15,695,512...15,752,941

G

coiled-coil domain containing 88B

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC88B mRNA

NCBI chr 1:213,466,139...213,482,099
Ensembl chr 1:213,461,963...213,522,302

G

coiled-coil domain containing 9

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC9 mRNA

NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:86,105,800...86,119,884

G

coiled-coil alpha-helical rod protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of CCHCR1 mRNA

NCBI chr20:3,210,383...3,223,187
Ensembl chr20:3,210,384...3,222,765

G

cholecystokinin B receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CCKBR mRNA

NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745

G

C-C motif chemokine ligand 11

increases secretion
increases expression
multiple interactions

ISO

Dextran Sulfate results in increased secretion of CCL11 protein
Dextran Sulfate results in increased expression of CCL11 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL11 mRNA; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of CCL11 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of CCL11 protein]

PMID:21858153 PMID:29950665 PMID:32033881

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575

G

C-C motif chemokine ligand 2

multiple interactions
increases expression
increases secretion

ISO

[RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased secretion of CCL2 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL2 mRNA; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of CCL2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of CCL2 protein]

PMID:19645018 PMID:20079348 PMID:21858153 PMID:24146755 PMID:29950665 More...

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 21

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL21A mRNA

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 24

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL24 mRNA

NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924

G

C-C motif chemokine ligand 25

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CCL25 mRNA

NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385

G

C-C motif chemokine ligand 27

increases expression

ISO

Dextran Sulfate results in increased expression of CCL27A mRNA

NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522

G

C-C motif chemokine ligand 28

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CCL28 mRNA

NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:53,334,071...53,358,709

G

C-C motif chemokine ligand 3

increases expression
multiple interactions

ISO
EXP

Dextran Sulfate results in increased expression of CCL3 mRNA
ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of CCL3 mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of CCL3 mRNA]
Dextran Sulfate results in increased expression of CCL3 protein
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of CCL3 protein]

PMID:19645018 PMID:30811821 PMID:33130971

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL4 mRNA

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine ligand 7

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CCL7 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL7 mRNA; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of CCL7 mRNA]

PMID:19645018 PMID:29950665 PMID:32033881

NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947

G

C-C motif chemokine ligand 9

increases expression
decreases expression

ISO

Dextran Sulfate results in increased expression of CCL6 mRNA
Dextran Sulfate results in decreased expression of CCL6 mRNA

PMID:19645018 PMID:35093514

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877

G

cyclin D1

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CCND1 mRNA; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CCND1 protein; [Dietary Fats co-treated with Dextran Sulfate] results in decreased expression of CCND1 protein; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CCND1 mRNA]; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CCND1 protein]; obeticholic acid inhibits the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in decreased expression of CCND1 protein]

PMID:31715269 PMID:35439472

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

C-C motif chemokine receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

C-C motif chemokine receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCR4 mRNA

NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642

G

C-C motif chemokine receptor 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCR5 mRNA

NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594

G

C-C motif chemokine receptor 7

multiple interactions

ISO

Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of CCR7 mRNA]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of CCR7 protein]

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501

G

C-C motif chemokine receptor 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCR8 mRNA

NCBI chr 8:128,703,966...128,705,926
Ensembl chr 8:128,702,349...128,705,955

G

C-C motif chemokine receptor like 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCRL2 mRNA

NCBI chr 8:119,912,671...119,915,313
Ensembl chr 8:119,911,288...119,922,380

G

centriole, cilia and spindle-associated protein

increases expression

ISO

Dextran Sulfate results in increased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469

G

CD14 molecule

affects response to substance
multiple interactions

ISO

Dextran Sulfate affects the susceptibility to CD14 protein
[Dextran Sulfate affects the susceptibility to CD14 protein] which affects the expression of IFNG mRNA; CD14 protein inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

CD163 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD163 mRNA

NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146

G

CD177 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD177 mRNA

NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:89,467,926...89,488,443

G

CD180 molecule

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CD180 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD180 mRNA

PMID:23894361 PMID:29950665

NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:35,589,451...35,603,982

G

CD19 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD19 mRNA

NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:190,417,853...190,424,355

G

Cd200 molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD200 mRNA

NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569

G

Cd247 molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD247 mRNA

NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248

G

CD274 molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD274 mRNA

NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951

G

Cd28 molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD28 mRNA

NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192

G

CD34 molecule

decreases expression

ISO

Dextran Sulfate results in decreased expression of CD34 mRNA

NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315

G

Cd4 molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD4 mRNA

NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461

G

CD44 molecule

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of CD44 mRNA

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

CD52 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD52 mRNA

NCBI chr 5:151,603,537...151,605,096
Ensembl chr 5:151,603,524...151,605,086

G

Cd53 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD53 mRNA

NCBI chr 2:197,040,369...197,087,925
Ensembl chr 2:197,040,369...197,218,593

G

CD55 molecule (Cromer blood group)

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD55 mRNA

NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107

G

Cd68 molecule

increases expression
multiple interactions
decreases expression

ISO

dextran sulfate increases expression of CD68 protein in colonic lamina propria of mice
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CD68 protein]

CTD
RGD

PMID:35362542 PMID:25004394

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

Cd72 molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD72 mRNA

NCBI chr 5:62,493,155...62,500,779
Ensembl chr 5:62,493,161...62,500,519

G

CD74 molecule

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of CD74 mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CD74 protein]
Dextran Sulfate results in decreased expression of CD74 mRNA; Dextran Sulfate results in decreased expression of CD74 protein

PMID:23894361 PMID:35093514 PMID:35362542

NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410

G

CD79a molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD79A mRNA

NCBI chr 1:89,621,460...89,625,813
Ensembl chr 1:89,621,460...89,625,812

G

CD79b molecule

increases expression

ISO

Dextran Sulfate results in increased expression of CD79B mRNA

NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,739,137...91,742,405

G

Cd81 molecule

decreases expression

ISO

Dextran Sulfate results in decreased expression of CD81 mRNA

NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092

G

CD86 molecule

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CD86 mRNA; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of CD86 protein]
Dextran Sulfate results in increased expression of CD86 mRNA; Dextran Sulfate results in increased expression of CD86 protein

PMID:29950665 PMID:38164749

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361

G

cytidine deaminase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CDA mRNA

NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541

G

cadherin 1

multiple interactions
decreases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in decreased expression of CDH1 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CDH1 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CDH1 mRNA
Dextran Sulfate results in decreased expression of CDH1 mRNA; Dextran Sulfate results in decreased expression of CDH1 protein

PMID:29950665 PMID:34273909 PMID:36543318 PMID:37385329

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

cadherin 2

multiple interactions
increases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of CDH2 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CDH2 protein

PMID:34273909 PMID:36543318

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CDH5 mRNA

NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822

G

cadherin-related family member 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CDHR2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CDHR2 protein]

NCBI chr17:9,881,979...9,917,698
Ensembl chr17:9,881,979...9,917,698

G

cyclin-dependent kinase 11B

increases expression

ISO

Dextran Sulfate results in increased expression of CDK11B mRNA

NCBI chr 5:171,495,042...171,521,143
Ensembl chr 5:171,495,776...171,521,145

G

cyclin-dependent kinase inhibitor 1C

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498

G

CDP-diacylglycerol synthase 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CDS2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CDS2 protein]

NCBI chr 3:139,967,870...140,006,459
Ensembl chr 3:139,967,742...140,009,201

G

caudal type homeo box 2

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CDX2 protein
Dextran Sulfate results in decreased expression of CDX2 protein
6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased expression of CDX2 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in decreased expression of CDX2 protein]

PMID:29680209 PMID:38663798

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

CCAAT/enhancer binding protein delta

increases expression

ISO

Dextran Sulfate results in increased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824

G

carboxyl ester lipase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CEL mRNA

NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019

G

centrosomal protein 131

increases expression

ISO

Dextran Sulfate results in increased expression of CEP131 mRNA

NCBI chr10:105,844,433...105,868,811
Ensembl chr10:105,844,433...105,868,797

G

carboxylesterase 1D

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of CES1D protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CES1D mRNA
Dextran Sulfate results in decreased expression of CES1D mRNA

PMID:29950665 PMID:35093514 PMID:35999755

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

carboxylesterase 2C

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:270,374,913...270,384,801

G

carboxylesterase 2E

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CES2E mRNA

NCBI chr19:157,447...172,822
Ensembl chr19:163,859...179,308

G

cilia and flagella associated protein 184

increases expression

ISO

Dextran Sulfate results in increased expression of CCDC96 mRNA

NCBI chr14:74,276,568...74,279,072
Ensembl chr14:78,486,414...78,507,808

G

cilia and flagella associated protein 45

increases expression

ISO

Dextran Sulfate results in increased expression of CFAP45 mRNA

NCBI chr13:87,521,831...87,545,236
Ensembl chr13:87,521,518...87,545,234

G

complement factor B

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of CFB protein

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

complement factor D

increases expression

ISO

Dextran Sulfate results in increased expression of CFD protein

NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572

G

complement factor H

multiple interactions
increases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of CFH protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CFH mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of CFH protein]
Dextran Sulfate results in increased expression of CFH mRNA; Dextran Sulfate results in increased expression of CFH protein

PMID:29950665 PMID:32272095 PMID:35093514 PMID:35999755

NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532

G

cofilin 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CFL1 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of CFL1 protein

NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353

G

CASP8 and FADD-like apoptosis regulator

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFLAR protein; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFLAR protein]; Camptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFLAR protein]; Plant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFLAR protein]

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

CF transmembrane conductance regulator

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFTR mRNA

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

cell growth regulator with EF hand domain 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of CGREF1 protein

NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800

G

chromatin assembly factor 1 subunit A

increases expression

ISO

Dextran Sulfate results in increased expression of CHAF1A mRNA

NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868

G

calcium homeostasis endoplasmic reticulum protein

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CHERP protein]

NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549

G

chromogranin A

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CHGA protein]

NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237

G

charged multivesicular body protein 2A

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CHMP2A protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CHMP2A protein]

NCBI chr 1:82,731,212...82,735,088
Ensembl chr 1:82,732,231...82,738,613

G

charged multivesicular body protein 4B

increases expression

ISO

Dextran Sulfate results in increased expression of CHMP4B mRNA

NCBI chr 3:163,631,054...163,671,569
Ensembl chr 3:163,631,054...163,671,569

G

chimerin 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CHN2 mRNA

NCBI chr 4:84,478,989...84,738,068
Ensembl chr 4:84,704,862...84,738,068

G

cysteine and histidine rich domain containing 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CHORDC1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CHORDC1 protein]

NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696

G

calcineurin-like EF-hand protein 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CHP1 protein]

NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443

G

chordin-like 2

increases expression

ISO

Dextran Sulfate results in increased expression of CHRDL2 mRNA

NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:163,755,316...163,782,757

G

cholinergic receptor, muscarinic 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CHRM4 mRNA

NCBI chr 3:98,349,080...98,356,821
Ensembl chr 3:98,348,650...98,358,771

G

cholinergic receptor nicotinic alpha 2 subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHRNA2 mRNA

NCBI chr15:44,517,862...44,534,144
Ensembl chr15:44,517,862...44,534,144

G

cholinergic receptor nicotinic alpha 7 subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHRNA7 mRNA

NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858

G

cholinergic receptor nicotinic beta 3 subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CHRNB3 mRNA

NCBI chr16:71,411,847...71,454,225
Ensembl chr16:71,417,039...71,454,225

G

cholinergic receptor nicotinic epsilon subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHRNE mRNA

NCBI chr10:55,829,835...55,838,853
Ensembl chr10:55,829,836...55,834,154

G

carbohydrate sulfotransferase 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CHST11 mRNA

NCBI chr 7:22,412,121...22,630,577
Ensembl chr 7:22,415,686...22,630,441

G

component of inhibitor of nuclear factor kappa B kinase complex

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CHUK protein modified form
notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of CHUK protein modified form]

NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273

G

CDGSH iron sulfur domain 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CISD1 protein]

NCBI chr20:17,254,462...17,267,843
Ensembl chr20:17,254,187...17,271,042

G

creatine kinase B

decreases expression

ISO

Dextran Sulfate results in decreased expression of CKB protein

NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478

G

creatine kinase, M-type

decreases expression

ISO

Dextran Sulfate results in decreased expression of CKM protein

NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719

G

chloride channel accessory 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CLCA1 mRNA

NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714

G

chloride channel accessory 4

increases expression

ISO

Dextran Sulfate results in increased expression of CLCA4 mRNA

NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435

G

chloride voltage-gated channel 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CLCN2 mRNA

NCBI chr11:93,702,382...93,716,059
Ensembl chr11:93,702,360...93,716,059

G

chloride voltage-gated channel 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CLCN3 mRNA

NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984

G

claudin 1

multiple interactions
increases expression
decreases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of CLDN1 protein]; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein; [SB 203580 co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 mRNA]; nuciferine inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein]
Dextran Sulfate results in decreased expression of CLDN1 mRNA; Dextran Sulfate results in decreased expression of CLDN1 protein

PMID:27920472 PMID:35894244 PMID:36543318 PMID:36577154 PMID:37001609 More...

NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529

G

claudin 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CLDN11 mRNA

NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539

G

claudin 2

multiple interactions
increases expression

ISO

6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased expression of CLDN2 mRNA]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased expression of CLDN2 protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of CLDN2 protein]; [Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of CLDN2 mRNA
Dextran Sulfate results in increased expression of CLDN2 mRNA; Dextran Sulfate results in increased expression of CLDN2 protein

PMID:26271895 PMID:29680209 PMID:36543318

NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377

G

C-type lectin domain containing 10A

increases expression

ISO

Dextran Sulfate results in increased expression of CLEC10A mRNA

NCBI chr10:55,374,914...55,379,110
Ensembl chr10:55,374,887...55,379,108

G

chloride intracellular channel 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CLIC1 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of CLIC1 protein

NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CLPP protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CLPP protein]

NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705

G

chymase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CMA1 mRNA

NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133

G

cytidine monophosphate N-acetylneuraminic acid synthetase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CMAS mRNA

NCBI chr 4:177,449,801...177,468,117
Ensembl chr 4:177,449,732...177,476,291

G

cytidine/uridine monophosphate kinase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CMPK1 protein

NCBI chr 5:133,717,073...133,744,623
Ensembl chr 5:133,717,086...133,744,596

G

cyclic nucleotide gated channel subunit alpha 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CNGA4 mRNA

NCBI chr 1:169,134,332...169,168,317
Ensembl chr 1:169,164,206...169,168,224

G

calponin 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of CNN2 protein

NCBI chr 7:10,363,141...10,370,312
Ensembl chr 7:10,363,102...10,370,312

G

cannabinoid receptor 1

decreases response to substance
increases expression
multiple interactions

ISO

CNR1 results in decreased susceptibility to Dextran Sulfate
Dextran Sulfate results in increased expression of CNR1 protein
SB 203580 inhibits the reaction [Dextran Sulfate results in increased expression of CNR1 protein]; Serotonin inhibits the reaction [Dextran Sulfate results in increased expression of CNR1 protein]

PMID:15085199 PMID:27920472 PMID:30611738

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

cannabinoid receptor 2

multiple interactions
increases response to substance
affects response to substance
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CNR2 mRNA; CNR2 gene mutant form promotes the reaction [Dextran Sulfate results in increased secretion of MPO protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]; CNR2 protein affects the susceptibility to [Azoxymethane co-treated with Dextran Sulfate]; SB 203580 inhibits the reaction [Dextran Sulfate results in increased expression of CNR2 protein]
CNR2 gene mutant form results in increased susceptibility to Dextran Sulfate
CNR2 protein affects the susceptibility to Dextran Sulfate

PMID:27611972 PMID:27920472 PMID:29950665 PMID:30102254 PMID:32942172

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961

G

ciliary neurotrophic factor receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CNTFR mRNA

NCBI chr 5:61,619,326...61,657,359
Ensembl chr 5:61,619,326...61,645,795

G

contactin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CNTN1 mRNA

NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391

G

component of oligomeric golgi complex 1

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of COG1 protein]

NCBI chr10:99,192,604...99,207,640
Ensembl chr10:99,194,568...99,208,437

G

collagen type XI alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL11A1 mRNA

NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264

G

collagen type XIV alpha 1 chain

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL14A1 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of COL14A1 protein]

PMID:29950665 PMID:32272095

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938

G

collagen type XVI alpha 1 chain

increases expression

ISO

Dextran Sulfate results in increased expression of COL16A1 mRNA

NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011

G

collagen type XVIII alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL18A1 mRNA

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112

G

collagen type I alpha 1 chain

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL1A1 mRNA
Dextran Sulfate results in decreased expression of COL1A1 mRNA

PMID:29950665 PMID:35093514

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

decreases expression

ISO

Dextran Sulfate results in decreased expression of COL1A2 mRNA

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type XXII alpha 1 chain

increases expression

ISO

Dextran Sulfate results in increased expression of COL22A1 mRNA

NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960

G

collagen type XXIII alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL23A1 mRNA

NCBI chr10:36,050,327...36,337,279
Ensembl chr10:36,050,259...36,337,897

G

collagen type XXVIII alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL28A1 mRNA

NCBI chr 4:36,069,980...36,223,128
Ensembl chr 4:37,035,761...37,189,494

G

collagen type III alpha 1 chain

decreases expression

ISO

Dextran Sulfate results in decreased expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type IV alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL4A1 mRNA

NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482

G

collagen type IV alpha 2 chain

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL4A2 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of COL4A2 protein]

PMID:29950665 PMID:32272095

NCBI chr16:84,749,672...84,885,520
Ensembl chr16:84,749,672...84,885,520

G

collagen type V alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL5A1 mRNA

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type VI alpha 1 chain

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of COL6A1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of COL6A1 protein]
Dextran Sulfate results in decreased expression of COL6A1 mRNA; Dextran Sulfate results in decreased expression of COL6A1 protein

PMID:32272095 PMID:35093514 PMID:35362542

NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107

G

collagen type VI alpha 2 chain

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of COL6A2 mRNA; Dextran Sulfate results in decreased expression of COL6A2 protein
Dextran Sulfate results in increased expression of COL6A2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of COL6A2 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of COL6A2 protein]

PMID:32272095 PMID:35093514 PMID:35362542

NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042

G

collagen type VI alpha 3 chain

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of COL6A3 protein]

NCBI chr 9:98,809,171...98,887,060
Ensembl chr 9:98,809,171...98,886,990

G

collagen type VIII alpha 1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of COL8A1 mRNA

NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229

G

collagen beta(1-O)galactosyltransferase 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COLGALT1 protein]

NCBI chr16:18,353,779...18,366,087
Ensembl chr16:18,353,570...18,366,086

G

COPI coat complex subunit zeta 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COPZ1 protein]

NCBI chr 7:136,287,696...136,314,131
Ensembl chr 7:136,288,032...136,314,135

G

coenzyme Q6 monooxygenase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of COQ6 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of COQ6 protein]

NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310

G

coronin 1A

decreases expression

ISO

Dextran Sulfate results in decreased expression of CORO1A protein

NCBI chr 1:190,726,129...190,731,133
Ensembl chr 1:190,726,130...190,731,102

G

coronin 1C

decreases expression

ISO

Dextran Sulfate results in decreased expression of CORO1C protein

NCBI chr12:48,373,573...48,445,718
Ensembl chr12:48,373,597...48,445,716

G

coactosin-like F-actin binding protein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of COTL1 protein

NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840

G

cytochrome c oxidase copper chaperone COX17

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of COX17 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COX17 protein]

NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019

G

cytochrome c oxidase subunit 5B

increases expression

ISO

Dextran Sulfate results in increased expression of COX5B mRNA

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403

G

cytochrome c oxidase subunit 7A2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of COX7A2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COX7A2 protein]

NCBI chr 8:89,597,051...89,611,032
Ensembl chr14:55,514,261...55,514,512
Ensembl chr 8:55,514,261...55,514,512

G

ceruloplasmin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CP mRNA

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

carboxypeptidase A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CPA1 mRNA

NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928

G

carboxypeptidase B2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CPB2 mRNA

NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962

G

copine 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CPNE1 protein]

NCBI chr 3:165,047,615...165,089,994

G

complement C3d receptor 2

increases expression

ISO

Dextran Sulfate results in increased expression of CR2 mRNA

NCBI chr13:109,207,034...109,244,980
Ensembl chr13:109,213,867...109,244,552

G

corticotropin releasing hormone receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CRHR1 mRNA

NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466

G

corticotropin releasing hormone receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CRHR2 mRNA

NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:85,554,268...85,596,318

G

cysteine-rich secretory protein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CRISP1 protein

NCBI chr 9:28,238,326...28,265,344
Ensembl chr 9:28,238,328...28,265,344

G

cartilage associated protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CRTAP mRNA

NCBI chr 8:122,926,117...122,945,843
Ensembl chr 8:122,926,117...122,945,843

G

colony stimulating factor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CSF1 mRNA

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

colony stimulating factor 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CSF2 mRNA; Dextran Sulfate results in increased expression of CSF2 protein
[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CSF2 mRNA; Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of CSF2 mRNA]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of CSF2 protein]

PMID:15652231 PMID:29950665 PMID:31442584

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

colony stimulating factor 2 receptor subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CSF2RB2 mRNA

NCBI chr 7:111,756,950...111,782,089
Ensembl chr 7:111,757,405...111,784,654

G

colony stimulating factor 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CSF3 mRNA
Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of CSF3 mRNA]

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860

G

colony stimulating factor 3 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CSF3R mRNA

NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411

G

casein kinase 1, alpha 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CSNK1A1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CSNK1A1 protein]

NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538

G

cystathionine gamma-lyase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CTH protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of CTH protein]

NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066

G

catenin beta 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CTNNB1 protein
[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of CTNNB1 protein; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased mutagenesis of CTNNB1 gene; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CTNNB1 protein; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of CTNNB1 protein]; CTNNB1 gene mutant form results in increased susceptibility to [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate]

PMID:15459021 PMID:16049979 PMID:27664423 PMID:31715269

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

CTP synthase 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CTPS1 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CTPS1 protein]

NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465

G

cathepsin C

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CTSC mRNA; Dextran Sulfate results in decreased expression of CTSC protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CTSC protein]

PMID:35093514 PMID:35362542

NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082

G

cathepsin D

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of CTSD protein]

NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821

G

cathepsin K

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CTSK mRNA

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cathepsin L

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of CTSL protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CTSL mRNA

PMID:29950665 PMID:35999755

NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113

G

cathepsin S

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of CTSS protein]

NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440

G

cubilin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CUBN mRNA

NCBI chr17:81,293,619...81,501,694
Ensembl chr17:81,293,619...81,501,694

G

C-X3-C motif chemokine receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CX3CR1 mRNA

NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983

G

CXADR, Ig-like cell adhesion molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CXADR mRNA

NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988

G

C-X-C motif chemokine ligand 10

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL10 mRNA]

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 12

decreases expression

ISO

Dextran Sulfate results in decreased expression of CXCL12 mRNA

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 13

increases expression

ISO

Dextran Sulfate results in increased expression of CXCL13 mRNA

PMID:23894361 PMID:35093514

NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,912,858...13,917,920

G

C-X-C motif chemokine ligand 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL14 mRNA

NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172

G

C-X-C motif chemokine ligand 2

multiple interactions
increases expression

ISO

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of CXCL2 mRNA]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein]
Dextran Sulfate results in increased expression of CXCL2 mRNA; Dextran Sulfate results in increased expression of CXCL2 protein

PMID:21724996 PMID:32033881 PMID:34998820 PMID:36519841

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

multiple interactions
increases secretion
increases expression

ISO

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CXCL1 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL1 mRNA; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of CXCL1 mRNA]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of CXCL1 protein]
Dextran Sulfate results in increased expression of CXCL1 mRNA; Dextran Sulfate results in increased expression of CXCL1 protein

PMID:19645018 PMID:20079348 PMID:21724996 PMID:21858153 PMID:29950665 More...

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

C-X-C motif chemokine ligand 6

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of CXCL5 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCL5 mRNA

PMID:19645018 PMID:29950665

NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417

G

C-X-C motif chemokine ligand 9

increases expression

ISO

Dextran Sulfate results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

C-X-C motif chemokine receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CXCR2 mRNA

NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602

G

cytochrome b-245 alpha chain

increases expression

ISO

Dextran Sulfate results in increased expression of CYBA protein

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytochrome b-245 beta chain

increases expression

ISO

Dextran Sulfate results in increased expression of CYBB mRNA; Dextran Sulfate results in increased expression of CYBB protein

PMID:20637373 PMID:23894361

NCBI chr X:16,030,596...16,065,065
Ensembl chr X:16,030,596...16,065,065

G

cytoplasmic FMR1 interacting protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CYFIP1 mRNA

NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292

G

cytoplasmic FMR1 interacting protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CYFIP2 mRNA

NCBI chr10:31,122,653...31,242,440
Ensembl chr10:31,122,653...31,242,440

G

cytoglobin

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of CYGB protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of CYGB protein]

NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CYP11A1 mRNA

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
decreases expression

ISO

6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in decreased expression of CYP1A1 mRNA]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in decreased expression of CYP1A1 protein]; Dextran Sulfate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
Dextran Sulfate results in decreased expression of CYP1A1 mRNA; Dextran Sulfate results in decreased expression of CYP1A1 protein

PMID:29680209 PMID:34998820

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions
decreases activity

EXP

[Dextran Sulfate results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of Acetaminophen

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 24, subfamily a, polypeptide 1

increases expression

ISO

Dextran Sulfate results in increased expression of CYP24A1 protein

NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083

G

cytochrome P450, family 26, subfamily b, polypeptide 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CYP26B1 mRNA

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176

G

cytochrome P450, family 27, subfamily b, polypeptide 1

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP27B1 mRNA
Dextran Sulfate results in decreased expression of CYP27B1 protein

PMID:29950665 PMID:38588969

NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570

G

cytochrome P450, family 2, subfamily b, polypeptide 1

decreases activity
multiple interactions

EXP

Dextran Sulfate results in decreased activity of CYP2B1 protein
[Dextran Sulfate results in decreased activity of CYP2B1 protein] which results in decreased chemical synthesis of hydroxybupropion

NCBI chr 1:90,646,098...90,669,762

G

cytochrome P450, family 2, subfamily b, polypeptide 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2B13 mRNA

NCBI chr 1:90,722,243...90,736,272

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily c, polypeptide 24

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2C55 mRNA

NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2C29 mRNA

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily c, polypeptide 66

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2C66 mRNA

NCBI chr 1:246,490,888...246,582,199
Ensembl chr 1:248,272,336...248,309,323

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases activity
multiple interactions

EXP

Dextran Sulfate results in decreased activity of CYP2E1 protein
[Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily j, polypeptide 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2J9 mRNA

NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042

G

cytochrome P450, family 2, subfamily r, polypeptide 1

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2R1 mRNA; Cholecalciferol inhibits the reaction [Dextran Sulfate results in decreased expression of CYP2R1 protein]

PMID:29950665 PMID:38588969

NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423

G

cytochrome P450, family 2, subfamily s, polypeptide 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP2S1 mRNA

NCBI chr 1:90,437,741...90,453,073
Ensembl chr 1:90,438,224...90,453,073

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP3A13 mRNA

NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154

G

cytochrome P450, family 4, subfamily b, polypeptide 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP4B1 mRNA

NCBI chr 5:134,375,807...134,413,635
Ensembl chr 5:134,375,807...134,393,116

G

cytochrome P450, family 4, subfamily f, polypeptide 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CYP4F14 mRNA

NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612

G

cytochrome P450, family 4, subfamily f, polypeptide 39

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CYP4F39 mRNA

NCBI chr 7:12,082,821...12,156,076
Ensembl chr 7:12,083,888...12,156,076

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

cytochrome P450 family 7 subfamily B member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CYP7B1 mRNA

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804

G

death-associated protein kinase 3

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of DAPK3 protein]

NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:9,174,904...9,183,272

G

dihydrolipoamide branched chain transacylase E2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of DBT protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of DBT protein]

NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525

G

decorin

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DCN mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of DCN protein]

PMID:29950665 PMID:32272095

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926

G

dynactin subunit 3

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of DCTN3 protein]

NCBI chr 5:61,676,950...61,684,958
Ensembl chr 5:61,676,950...61,684,903

G

discoidin domain receptor tyrosine kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DDR2 mRNA

NCBI chr13:84,726,412...84,851,032
Ensembl chr13:84,731,180...84,850,288

G

DEAD-box helicase 23

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of DDX23 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of DDX23 protein]

NCBI chr 7:131,676,636...131,693,917
Ensembl chr 7:131,676,636...131,689,074

G

DEPP autophagy regulator 1

increases expression

ISO

Dextran Sulfate results in increased expression of DEPP1 mRNA

NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:151,581,502...151,586,233

G

derlin 3

increases expression

ISO

Dextran Sulfate results in increased expression of DERL3 mRNA

NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477

G

diacylglycerol kinase, beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DGKB mRNA

NCBI chr 6:60,368,101...61,124,420
Ensembl chr 6:60,368,519...61,124,420

G

diacylglycerol kinase, iota

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DGKI mRNA

NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832

G

24-dehydrocholesterol reductase

decreases expression

ISO

Dextran Sulfate results in decreased expression of DHCR24 mRNA

NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936

G

dihydrodiol dehydrogenase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of DHDH protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of DHDH protein]

NCBI chr 1:105,088,108...105,102,560
Ensembl chr 1:105,090,309...105,101,567

G

dihydroorotate dehydrogenase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of DHODH protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of DHODH protein]

NCBI chr19:54,460,636...54,483,049
Ensembl chr19:54,468,690...54,514,496

G

dehydrogenase/reductase 9

increases expression

ISO

Dextran Sulfate results in increased expression of DHRS9 mRNA

NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376

G

dehydrogenase/reductase X-linked

increases expression

ISO

Dextran Sulfate results in increased expression of DHRSX mRNA

NCBI chr12:16,299,768...16,304,553
Ensembl chr12:21,413,575...21,418,319

G

diaphanous-related formin 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of DIAPH1 protein]

NCBI chr18:29,920,889...30,020,280
Ensembl chr18:29,920,889...30,020,280

G

dickkopf WNT signaling pathway inhibitor 2

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of DKK2 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of DKK2 mRNA]

NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:223,242,377...223,334,724

G

delta like non-canonical Notch ligand 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DLK1 mRNA

NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529

G

DM1 protein kinase

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of DMPK mRNA

NCBI chr 1:87,858,294...87,868,624
Ensembl chr 1:87,858,316...87,868,910

G

DMRT-like family A1

decreases expression

ISO

Dextran Sulfate results in decreased expression of DMRTA1 mRNA

NCBI chr 5:109,531,704...109,538,244
Ensembl chr 5:109,531,586...109,538,246

G

DM1 locus, WD repeat containing

increases expression

ISO

Dextran Sulfate results in increased expression of DMWD mRNA

NCBI chr 1:78,722,436...78,729,224
Ensembl chr 1:87,850,604...87,857,624

G

DnaJ heat shock protein family (Hsp40) member B4

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of DNAJB4 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of DNAJB4 protein]

NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042

G

DnaJ heat shock protein family (Hsp40) member C10

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of DNAJC10 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of DNAJC10 protein]

NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368

G

dynamin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DNM1 mRNA

NCBI chr 3:36,002,535...36,055,220
Ensembl chr 3:36,002,064...36,046,289

G

dynamin 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DNM3 mRNA

NCBI chr13:76,892,381...77,371,346
Ensembl chr13:76,892,171...77,371,350

G

dedicator of cyto-kinesis 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of DOCK1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of DOCK1 protein]

NCBI chr 1:198,897,021...199,413,636
Ensembl chr 1:198,897,045...199,413,627

G

docking protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DOK2 mRNA

NCBI chr15:52,237,046...52,251,091
Ensembl chr15:52,236,900...52,251,074

G

dipeptidase 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of DPEP1 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of DPEP1 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of DPEP1 protein]

PMID:32272095 PMID:35999755

NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775

G

dipeptidase 2

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of DPEP2 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DPEP2 mRNA

PMID:29950665 PMID:35999755

NCBI chr19:50,795,322...50,806,320
Ensembl chr19:50,795,327...50,801,757
Ensembl chr19:50,795,327...50,801,757

G

dihydropyrimidine dehydrogenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DPYD mRNA

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778

G

Dr1 associated protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of DRAP1 mRNA

NCBI chr 1:212,161,107...212,163,833
Ensembl chr 1:212,161,125...212,163,762

G

dopamine receptor D4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DRD4 mRNA

NCBI chr 1:205,825,937...205,829,124
Ensembl chr 1:205,826,049...205,830,458

G

dopamine receptor D5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of DRD5 mRNA

NCBI chr14:76,700,244...76,703,344
Ensembl chr14:76,700,241...76,703,466

G

deltex E3 ubiquitin ligase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of DTX1 mRNA

NCBI chr12:41,510,252...41,541,433
Ensembl chr12:41,510,264...41,541,430

G

dual oxidase maturation factor 2

increases expression

ISO

Dextran Sulfate results in increased expression of DUOXA2 mRNA

NCBI chr 3:129,698,938...129,702,656
Ensembl chr 3:129,698,092...129,702,656

G

dual specificity phosphatase 1

multiple interactions
increases expression

ISO

DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; DUSP1 protein affects the susceptibility to [Azoxymethane co-treated with Dextran Sulfate]
Dextran Sulfate results in increased expression of DUSP1 mRNA

PMID:30844440 PMID:35093514

NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644

G

enoyl-CoA delta isomerase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ECI1 mRNA

NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773

G

Ecm29 proteasome adaptor and scaffold

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ECPAS protein
Dextran Sulfate results in increased expression of ECPAS protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ECPAS protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ECPAS protein]

PMID:32272095 PMID:35362542

NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908

G

ectodysplasin-A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDA mRNA

NCBI chr X:69,118,577...69,520,274
Ensembl chr X:69,118,796...69,520,274

G

ectodysplasin A2 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDA2R mRNA

NCBI chr X:66,225,557...66,280,674
Ensembl chr X:66,236,111...66,280,663

G

endothelial differentiation-related factor 1

increases expression

ISO

Dextran Sulfate results in increased expression of EDF1 mRNA

NCBI chr 3:28,764,906...28,779,499

G

endothelin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

endothelin 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of EDN2 protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of EDN2 mRNA

PMID:16216902 PMID:29950665

NCBI chr 5:139,036,576...139,042,074
Ensembl chr 5:139,036,492...139,043,070

G

endothelin receptor type A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDNRA mRNA

NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284

G

eukaryotic translation elongation factor 1 gamma

decreases expression

ISO

Dextran Sulfate results in decreased expression of EEF1G protein

NCBI chr 1:215,289,815...215,300,421
Ensembl chr 1:215,277,860...215,301,479

G

EGF containing fibulin extracellular matrix protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EFEMP2 mRNA

NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739

G

EF-hand domain family, member D2

increases expression

ISO

Dextran Sulfate results in increased expression of EFHD2 mRNA

NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:159,443,960...159,460,369

G

ephrin A1

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of EFNA1 mRNA

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726

G

egl-9 family hypoxia-inducible factor 2

increases expression

ISO

Dextran Sulfate results in increased expression of EGLN2 mRNA

NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:91,579,206...91,587,385

G

EH-domain containing 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of EHD1 protein

NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485

G

EH-domain containing 4

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of EHD4 protein
Dextran Sulfate results in decreased expression of EHD4 protein

NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of EHHADH mRNA

NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662

G

euchromatic histone lysine methyltransferase 2

increases expression

ISO

Dextran Sulfate results in increased expression of EHMT2 mRNA

NCBI chr20:3,924,263...3,941,238
Ensembl chr20:3,924,263...3,941,384

G

eukaryotic translation initiation factor 2-alpha kinase 2

multiple interactions
increases phosphorylation

ISO

EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased activity of CASP3 protein]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; GW 506033X inhibits the reaction [Dextran Sulfate results in increased phosphorylation of EIF2AK2 protein]

NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116

G

eukaryotic translation initiation factor 2B subunit epsilon

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of EIF2B5 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of EIF2B5 protein]

NCBI chr11:93,898,814...93,909,431
Ensembl chr11:93,898,814...93,908,800

G

eukaryotic translation initiation factor 3, subunit A

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of EIF3A mRNA

NCBI chr 1:269,888,730...269,925,785
Ensembl chr 1:269,888,615...269,919,025

G

eukaryotic translation initiation factor 5A

decreases expression

ISO

Dextran Sulfate results in decreased expression of EIF5A protein

NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330

G

eukaryotic translation initiation factor 5B

increases expression

ISO

Dextran Sulfate results in increased expression of EIF5B mRNA

NCBI chr 9:47,718,706...47,773,289
Ensembl chr 9:47,718,706...47,778,583

G

elastase, neutrophil expressed

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ELANE mRNA

NCBI chr 7:10,467,877...10,469,725
Ensembl chr 7:10,467,877...10,469,725

G

engulfment and cell motility 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ELMO2 mRNA

NCBI chr 3:174,442,965...174,716,723
Ensembl chr 3:174,442,965...174,480,459

G

ER membrane protein complex subunit 2

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of EMC2 protein]

NCBI chr 7:76,471,899...76,508,866
Ensembl chr 7:76,471,899...76,510,178

G

epithelial membrane protein 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of EMP2 mRNA

NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532

G

endoglin

decreases expression

ISO

Dextran Sulfate results in decreased expression of ENG mRNA

NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933

G

enolase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of ENO1 protein

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

enolase 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ENO2 protein]

NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220

G

enolase 3

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of ENO3 protein; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ENO3 protein]

PMID:32272095 PMID:35999755

NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,866,101...55,874,540

G

glutamyl aminopeptidase

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ENPEP protein]

NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218

G

ectonucleoside triphosphate diphosphohydrolase 5

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of ENTPD5 mRNA

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495

G

E1A binding protein p300

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

epoxide hydrolase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of EPHX1 mRNA

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

erb-b2 receptor tyrosine kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ERBB2 mRNA

NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481

G

erb-b2 receptor tyrosine kinase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ERBB3 mRNA

NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:1,579,816...1,601,120

G

erb-b2 receptor tyrosine kinase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ERBB4 mRNA

NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:76,973,227...78,045,772

G

epiregulin

decreases response to substance
increases expression

ISO

EREG protein results in decreased susceptibility to Dextran Sulfate
dextran sodium sulfate increases expression of Ereg protein in colonic mucosa

CTD
RGD

PMID:15456865 PMID:20498653

NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260

G

endoplasmic reticulum metallopeptidase 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ERMP1 protein]

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197

G

endoplasmic reticulum oxidoreductase 1 alpha

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ERO1A protein]

NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039

G

ERBB receptor feedback inhibitor 1

increases expression

ISO

Dextran Sulfate results in increased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

endothelial cell adhesion molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ESAM mRNA

NCBI chr 8:45,426,985...45,437,976
Ensembl chr 8:45,425,731...45,437,973

G

estrogen receptor 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ESR1 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ESR1 mRNA

PMID:29950665 PMID:30270565

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen receptor 2

multiple interactions

ISO

Dextran Sulfate promotes the reaction [Zearalenone results in increased expression of ESR2 mRNA]

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709

G

Enah/Vasp-like

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EVL mRNA

NCBI chr 6:133,238,547...133,358,730
Ensembl chr 6:133,238,547...133,358,729

G

EWS RNA-binding protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of EWSR1 mRNA

NCBI chr14:84,179,413...84,208,149
Ensembl chr14:84,179,618...84,208,095

G

coagulation factor X

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of F10 mRNA

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

G

coagulation factor XI

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of F11 protein

NCBI chr16:53,720,502...53,741,547
Ensembl chr16:53,718,621...53,740,941

G

F11 receptor

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of F11R protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of F11R protein]

NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816

G

coagulation factor XIII A1 chain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of F13A1 mRNA

NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948

G

coagulation factor II (thrombin) receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of F2R mRNA

NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579

G

F2R like trypsin receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of F2RL1 mRNA

NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954

G

coagulation factor V

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of F5 mRNA

NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247

G

fatty acid amide hydrolase

multiple interactions

ISO

[Serotonin co-treated with Dextran Sulfate] results in decreased expression of FAAH protein

NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396

G

fatty acid binding protein 4

multiple interactions
increases expression

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of FABP4 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of FABP4 protein]

PMID:26271895 PMID:32272095

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

fatty acid binding protein 5

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of FABP5 protein]

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

fatty acid binding protein 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FABP6 mRNA

NCBI chr10:28,565,054...28,569,727
Ensembl chr10:28,565,054...28,573,058

G

fatty acid desaturase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of FADS1 mRNA

NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615

G

fatty acid desaturase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of FADS2 mRNA

NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066

G

family with sequence similarity 136, member A

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of FAM136A protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of FAM136A protein]

NCBI chr 4:120,362,563...120,368,479
Ensembl chr 4:120,362,561...120,368,479

G

family with sequence similarity 229, member A

increases expression

ISO

Dextran Sulfate results in increased expression of FAM229A mRNA

NCBI chr 5:141,829,716...141,830,705
Ensembl chr 5:147,113,997...147,114,785

G

family with sequence similarity 234, member A

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of FAM234A protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of FAM234A protein]

NCBI chr10:15,736,741...15,768,043
Ensembl chr10:15,736,742...15,749,835

G

family with sequence similarity 50, member B

increases expression

ISO

Dextran Sulfate results in increased expression of FAM50B mRNA

NCBI chr17:30,174,431...30,193,627
Ensembl chr17:30,379,171...30,399,651

G

family with sequence similarity 98, member B

increases expression

ISO

Dextran Sulfate results in increased expression of FAM98B mRNA

NCBI chr 3:124,588,827...124,618,275
Ensembl chr 3:124,588,827...124,618,275

G

FAU ubiquitin like and ribosomal protein S30 fusion

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of FAU protein]

NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:212,779,473...212,781,026
Ensembl chr 1:212,779,473...212,781,026

G

filamin binding LIM protein 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of FBLIM1 protein]

NCBI chr 5:159,167,004...159,198,578
Ensembl chr 5:159,167,004...159,196,853

G

fibulin 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FBLN2 mRNA

NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029

G

fibulin 5

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FBLN5 mRNA
Dextran Sulfate results in decreased expression of FBLN5 mRNA

PMID:29950665 PMID:35093514

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

fibrillin 1

multiple interactions
increases expression
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FBN1 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of FBN1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of FBN1 protein]

PMID:29950665 PMID:32272095 PMID:35362542

NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283

G

F-box protein 2

increases expression

ISO

Dextran Sulfate results in increased expression of FBXO2 mRNA

NCBI chr 5:163,876,079...163,881,508
Ensembl chr 5:163,875,757...163,881,508

G

Fc epsilon receptor Ig

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FCER1G mRNA

NCBI chr13:86,181,908...86,186,766
Ensembl chr13:86,181,908...86,186,859

G

Fc gamma receptor 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FCGR1 mRNA

NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:186,539,942...186,548,858

G

Fc gamma receptor 2A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FCGR3 mRNA

NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394

G

Fc gamma receptor 2B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FCGR2B mRNA

NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517

G

Fc gamma receptor 3A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FCGR4 mRNA

NCBI chr13:85,782,636...85,792,656
Ensembl chr13:85,782,490...85,792,651

G

fucose kinase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FCSK mRNA

NCBI chr19:55,743,746...55,783,873
Ensembl chr19:55,739,842...55,800,496

G

ferredoxin 1

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of FDX1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of FDX1 protein]

PMID:32272095 PMID:35362542

NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583

G

ferredoxin reductase

decreases expression

ISO

Dextran Sulfate results in decreased expression of FDXR mRNA

NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542

G

FERM domain containing kindlin 3

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of FERMT3 protein
Dextran Sulfate results in decreased expression of FERMT3 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of FERMT3 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of FERMT3 protein]

PMID:32272095 PMID:35999755

NCBI chr 1:213,618,691...213,636,889
Ensembl chr 1:213,618,208...213,636,273

G

free fatty acid receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FFAR2 mRNA

NCBI chr 1:95,199,277...95,202,599
Ensembl chr 1:95,199,271...95,202,623

G

free fatty acid receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FFAR4 mRNA

NCBI chr 1:245,286,009...245,304,029
Ensembl chr 1:245,285,883...245,304,031

G

fibrinogen alpha chain

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of FGA protein]

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

fibroblast growth factor 18

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FGF18 mRNA

NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933

G

fibroblast growth factor 19

multiple interactions

ISO

Dextran Sulfate results in increased expression of and results in increased secretion of FGF15 protein

NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267

G

fibroblast growth factor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 23

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FGF23 mRNA

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991

G

fibroblast growth factor 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FGF8 mRNA

NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605

G

fibroblast growth factor 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FGF9 mRNA

NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926

G

Fibroblast growth factor receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FGFR1 mRNA

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

fibroblast growth factor receptor 4

increases expression

ISO

Dextran Sulfate results in increased expression of FGFR4 mRNA

NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389

G

fibrinogen-like 1

increases expression

ISO

Dextran Sulfate results in increased expression of FGL1 protein

NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429

G

four and a half LIM domains 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of FHL1 protein

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282

G

four and a half LIM domains 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326

G

four and a half LIM domains 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of FHL3 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of FHL3 protein]

NCBI chr 5:142,238,634...142,246,011
Ensembl chr 5:142,235,109...142,246,034

G

filamin A

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of FLNA protein

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

flotillin 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of FLOT2 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of FLOT2 protein]

NCBI chr10:63,424,084...63,445,811
Ensembl chr10:63,423,806...63,445,810

G

Fms related receptor tyrosine kinase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FLT1 mRNA

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FLT4 mRNA

NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645

G

flavin containing dimethylaniline monoxygenase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FMO1 mRNA

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

fibromodulin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FMOD mRNA

NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183

G

fibronectin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

ISO

Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]; GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]
Dextran Sulfate results in increased expression of FOS mRNA

PMID:18687398 PMID:35093514

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FOS like 1, AP-1 transcription factor subunit

increases expression

ISO

Dextran Sulfate results in increased expression of FOSL1 protein

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

forkhead box A2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FOXA2 mRNA

NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757

G

forkhead box A3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FOXA3 mRNA

NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:87,790,012...87,800,953

G

forkhead box O1

increases expression

ISO

Dextran Sulfate results in increased expression of FOXO1 mRNA; Dextran Sulfate results in increased expression of FOXO1 protein

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419

G

forkhead box O3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

forkhead box O4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FOXO4 mRNA

NCBI chr X:70,425,218...70,432,120
Ensembl chr X:70,425,563...70,432,120

G

forkhead box P3

increases methylation
increases expression
multiple interactions

ISO
EXP

Dextran Sulfate results in increased methylation of FOXP3 gene
Dextran Sulfate results in increased expression of FOXP3 mRNA
kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of FOXP3 mRNA]
Chlorpyrifos inhibits the reaction [Dextran Sulfate results in increased expression of FOXP3 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased methylation of FOXP3 gene]

PMID:20881082 PMID:21858153 PMID:31807802 PMID:34998820

NCBI chr X:17,580,380...17,601,181
Ensembl chr X:17,580,380...17,595,894

G

fucose-1-phosphate guanylyltransferase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FPGT mRNA

NCBI chr 2:246,757,982...246,778,896
Ensembl chr 2:246,757,986...246,778,848

G

formyl peptide receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FPR1 mRNA

NCBI chr 1:67,417,991...67,429,813
Ensembl chr 1:67,421,313...67,422,520

G

formyl peptide receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FPR2 mRNA

NCBI chr 1:67,449,637...67,458,272
Ensembl chr 1:67,449,637...67,458,272

G

formyl peptide receptor 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FPR3 mRNA

NCBI chr 1:67,557,464...67,566,509
Ensembl chr 1:67,518,199...67,566,519

G

FRAT regulator of WNT signaling pathway 2

increases expression

ISO

Dextran Sulfate results in increased expression of FRAT2 mRNA

NCBI chr 1:240,654,120...240,656,449
Ensembl chr 1:250,603,088...250,606,921

G

follicle stimulating hormone subunit beta

multiple interactions
decreases expression

ISO

gingerol inhibits the reaction [Dextran Sulfate results in decreased expression of FSHB protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased expression of FSHB protein]

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

follicle stimulating hormone receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FSHR mRNA

NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:10,952,329...11,160,288

G

follistatin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FST mRNA

NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491

G

follistatin like 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FSTL3 mRNA

NCBI chr 7:10,574,195...10,579,844
Ensembl chr 7:10,574,186...10,590,509

G

ferritin heavy chain 1

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FTH1 protein; sinpeinine A inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FTH1 protein]

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214

G

alpha-L-fucosidase 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of FUCA1 protein]

NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511

G

Fus RNA binding protein

increases expression

ISO

Dextran Sulfate results in increased expression of FUS mRNA

NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884

G

FXYD domain-containing ion transport regulator 1

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD1 mRNA
Dextran Sulfate results in decreased expression of FXYD1 mRNA

PMID:29950665 PMID:35093514

NCBI chr 1:95,414,556...95,418,645
Ensembl chr 1:95,414,557...95,418,591

G

FXYD domain-containing ion transport regulator 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD3 mRNA

NCBI chr 1:95,432,918...95,440,129
Ensembl chr 1:95,432,919...95,439,702

G

FXYD domain-containing ion transport regulator 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FXYD4 mRNA

NCBI chr 4:152,782,181...152,786,118
Ensembl chr 4:152,782,181...152,786,039

G

FYN proto-oncogene, Src family tyrosine kinase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FYN mRNA

NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479

G

frizzled class receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FZD1 mRNA

NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176

G

frizzled class receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FZD4 mRNA

NCBI chr 1:152,692,507...152,701,372
Ensembl chr 1:152,692,507...152,701,372

G

frizzled class receptor 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FZD5 mRNA

NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612

G

frizzled class receptor 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FZD6 mRNA

NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680

G

frizzled class receptor 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of FZD7 mRNA

NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:68,411,259...68,432,585

G

frizzled class receptor 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of FZD8 mRNA

NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961

G

glucose-6-phosphatase catalytic subunit 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of G6PC1 mRNA

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

gamma-aminobutyric acid type B receptor subunit 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GABBR1 mRNA

NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,469,779...1,498,607

G

gamma-aminobutyric acid type A receptor subunit alpha 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GABRA2 mRNA

NCBI chr14:37,451,218...37,587,458
Ensembl chr14:37,450,683...37,587,457

G

gamma-aminobutyric acid type A receptor subunit alpha 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GABRA5 mRNA

NCBI chr 1:117,404,446...117,517,424
Ensembl chr 1:117,404,494...117,516,635

G

gamma-aminobutyric acid type A receptor subunit beta 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GABRB2 mRNA

NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171

G

gamma-aminobutyric acid type A receptor subunit delta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GABRD mRNA

NCBI chr 5:171,240,813...171,252,709
Ensembl chr 5:171,240,789...171,253,094

G

glutamate decarboxylase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAD1 mRNA

NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759

G

UDP-galactose-4-epimerase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALE mRNA

NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:153,478,325...153,481,922

G

galactokinase 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GALK1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GALK1 protein]

NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258

G

galactokinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALK2 mRNA

NCBI chr 3:133,563,524...133,696,423
Ensembl chr 3:133,563,538...133,696,528

G

galactose mutarotase

increases expression

ISO

Dextran Sulfate results in increased expression of GALM mRNA

NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417

G

polypeptide N-acetylgalactosaminyltransferase 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GALNT1 protein]

NCBI chr18:15,763,697...15,843,598
Ensembl chr18:15,764,277...15,843,588

G

polypeptide N-acetylgalactosaminyltransferase 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT10 mRNA

NCBI chr10:41,821,216...41,967,618
Ensembl chr10:42,322,161...42,468,087

G

polypeptide N-acetylgalactosaminyltransferase 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT12 mRNA

NCBI chr 5:66,180,171...66,208,931
Ensembl chr 5:66,180,164...66,208,938

G

polypeptide N-acetylgalactosaminyltransferase 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GALNT15 mRNA

NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285

G

polypeptide N-acetylgalactosaminyltransferase 16

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GALNT16 mRNA

NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:105,901,153...105,991,350

G

polypeptide N-acetylgalactosaminyltransferase 18

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GALNT18 mRNA

NCBI chr 1:175,027,832...175,338,883
Ensembl chr 1:175,027,839...175,338,883

G

polypeptide N-acetylgalactosaminyltransferase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GALNT2 mRNA

NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237

G

polypeptide N-acetylgalactosaminyltransferase 3

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GALNT3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GALNT3 protein]

NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323

G

polypeptide N-acetylgalactosaminyltransferase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT4 mRNA

NCBI chr 7:33,925,229...33,927,770

G

polypeptide N-acetylgalactosaminyltransferase 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT5 mRNA

NCBI chr 3:62,982,465...63,028,724
Ensembl chr 3:62,982,465...63,028,724

G

polypeptide N-acetylgalactosaminyltransferase 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT6 mRNA

NCBI chr 7:133,668,612...133,715,909
Ensembl chr 7:133,668,615...133,698,439

G

polypeptide N-acetylgalactosaminyltransferase 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNT7 mRNA

NCBI chr16:37,589,368...37,713,911
Ensembl chr16:37,589,425...37,713,909

G

polypeptide N-acetylgalactosaminyltransferase-like 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GALNTL6 mRNA

NCBI chr16:36,203,674...37,454,709
Ensembl chr16:36,204,614...37,452,780

G

GAR1 ribonucleoprotein

increases expression

ISO

Dextran Sulfate results in increased expression of GAR1 mRNA

NCBI chr 2:221,049,471...221,056,749
Ensembl chr 2:221,049,473...221,056,749

G

growth arrest specific 8

increases expression

ISO

Dextran Sulfate results in increased expression of GAS8 mRNA

NCBI chr19:68,461,280...68,480,810
Ensembl chr19:68,461,304...68,480,806

G

gastrin

decreases response to substance
multiple interactions

ISO

GAST protein modified form results in decreased susceptibility to Dextran Sulfate
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GAST mRNA

PMID:16618411 PMID:29950665

NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880

G

GATA binding protein 2

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of GATA2 mRNA

NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055

G

guanylate binding protein 4

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GBP4 protein]

NCBI chr 2:233,978,163...233,992,124
Ensembl chr 2:233,978,486...233,992,120

G

guanylate binding protein family member 6

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GBP9 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of GBP9 protein]

NCBI chr14:5,034,999...5,062,023
Ensembl chr14:4,968,325...4,983,692
Ensembl chr14:4,968,325...4,983,692

G

guanylate binding protein 7

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GBP7 protein]

NCBI chr 2:233,948,774...233,970,532
Ensembl chr 2:233,948,677...233,970,526

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

glucosaminyl (N-acetyl) transferase 3, mucin type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCNT3 mRNA

NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595

G

guanine deaminase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GDA protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GDA protein]

NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348

G

GDP dissociation inhibitor 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of GDI1 protein

NCBI chr X:157,238,900...157,245,562
Ensembl chr X:157,238,892...157,245,560

G

glycerophosphodiester phosphodiesterase domain containing 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GDPD1 protein]

NCBI chr10:72,318,716...72,381,143
Ensembl chr10:72,337,778...72,381,120

G

glutamine fructose-6-phosphate transaminase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GFPT1 mRNA

NCBI chr 4:121,054,023...121,103,799
Ensembl chr 4:121,054,045...121,103,799

G

glutamine-fructose-6-phosphate transaminase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GFPT2 mRNA

NCBI chr10:34,616,146...34,662,420
Ensembl chr10:34,615,370...34,662,419

G

GDP-L-fucose synthase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GFUS mRNA

NCBI chr 7:109,492,808...109,497,719
Ensembl chr 7:109,492,809...109,497,662

G

golgi-associated, olfactory signaling regulator

increases expression

ISO

Dextran Sulfate results in increased expression of GFY mRNA

NCBI chr 1:95,661,621...95,665,300
Ensembl chr 1:104,798,267...104,801,344

G

gamma-glutamyl cyclotransferase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GGCT mRNA

NCBI chr 4:85,453,387...85,459,597
Ensembl chr 4:85,453,387...85,470,224

G

gamma-glutamyl hydrolase

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GGH protein]

NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647

G

gametogenetin binding protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of GGNBP1 mRNA

NCBI chr20:5,111,734...5,118,034
Ensembl chr20:5,101,165...5,118,030

G

growth hormone 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GH mRNA

NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859

G

ghrelin and obestatin prepropeptide

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GHRL mRNA

NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:148,421,315...148,425,969

G

GIPC PDZ domain containing family, member 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GIPC2 protein]

NCBI chr 2:243,690,742...243,770,199
Ensembl chr 2:243,690,748...243,770,199

G

galactosidase, beta 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GLB1 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of GLB1 protein]

NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:122,963,718...123,036,326

G

galactosidase, beta 1-like 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of GLB1L2 mRNA

NCBI chr 8:25,115,462...25,166,843
Ensembl chr 8:33,390,678...33,442,695

G

GLI family zinc finger 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of GLI1 mRNA

NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:65,042,237...65,054,540

G

GLI family zinc finger 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GLI3 mRNA

NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198

G

glucagon-like peptide 1 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GLP1R mRNA

NCBI chr20:8,973,393...9,011,622
Ensembl chr20:8,973,352...9,011,654

G

glutaredoxin 5

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GLRX5 protein]

NCBI chr 6:129,752,902...129,763,278
Ensembl chr 6:129,752,840...129,763,278

G

glutaminase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GLS protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of GLS protein]

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861

G

GDP-mannose 4, 6-dehydratase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GMDS mRNA

NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,304,056...32,830,706

G

guanosine monophosphate reductase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GMPR protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GMPR protein]

NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,357,992...19,431,655

G

G protein subunit alpha 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GNA11 mRNA

NCBI chr 7:8,814,285...8,828,628
Ensembl chr 7:8,814,327...8,830,558

G

G protein subunit alpha 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNA12 mRNA

NCBI chr12:18,919,629...19,000,185
Ensembl chr12:18,919,629...19,000,185

G

G protein subunit alpha 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNA14 mRNA

NCBI chr 1:223,141,802...223,324,210
Ensembl chr 1:223,141,802...223,324,210

G

G protein subunit alpha 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GNA15 mRNA

NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268

G

G protein subunit alpha o1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GNAO1 protein]

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437

G

G protein subunit alpha z

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNAZ mRNA

NCBI chr20:13,642,853...13,693,616
Ensembl chr20:13,644,020...13,669,287

G

G protein subunit beta 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNB3 mRNA

NCBI chr 4:159,325,741...159,331,443
Ensembl chr 4:159,325,742...159,331,445

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GNE mRNA

NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251

G

G protein subunit gamma 12

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GNG12 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GNG12 protein]

NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476

G

G protein subunit gamma 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNG4 mRNA

NCBI chr17:93,432,791...93,481,709
Ensembl chr17:93,433,195...93,481,709

G

G protein subunit gamma 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNG7 mRNA

NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923

G

G protein subunit gamma 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNG8 mRNA

NCBI chr 1:86,692,609...86,696,463
Ensembl chr 1:86,692,642...86,696,408

G

G protein subunit gamma transducin 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GNGT2 mRNA

NCBI chr10:81,271,916...81,280,980
Ensembl chr10:81,277,423...81,280,970

G

G protein nucleolar 1

increases expression

ISO

Dextran Sulfate results in increased expression of GNL1 mRNA

NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,787,940...2,797,577

G

glucosamine-phosphate N-acetyltransferase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GNPNAT1 mRNA

NCBI chr15:21,076,129...21,088,526
Ensembl chr15:21,076,130...21,088,423

G

golgin A3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GOLGA3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GOLGA3 protein]

NCBI chr12:52,112,129...52,160,311
Ensembl chr12:52,114,590...52,160,226

G

golgin A4

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of GOLGA4 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GOLGA4 protein]

NCBI chr 8:127,085,830...127,163,227
Ensembl chr 8:127,085,848...127,163,603

G

glutamic-oxaloacetic transaminase 1

multiple interactions
increases activity

ISO

Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased activity of GOT1 protein]

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycoprotein Ib platelet subunit beta

increases expression

ISO

Dextran Sulfate results in increased expression of GP1BB mRNA

NCBI chr11:95,882,561...95,883,738

G

glycoprotein VI

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of GP6 protein

NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:78,508,468...78,535,374

G

G protein-coupled bile acid receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPBAR1 mRNA

NCBI chr 9:83,309,895...83,312,397
Ensembl chr 9:83,311,246...83,315,608

G

glypican 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPC4 mRNA

NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057

G

glucose-6-phosphate isomerase

decreases expression

ISO

Dextran Sulfate results in decreased expression of GPI protein

NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261

G

glycoprotein nmb

increases expression

ISO

Dextran Sulfate results in increased expression of GPNMB mRNA

NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240

G

G protein-coupled receptor 119

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of GPR119 mRNA

NCBI chr X:127,852,145...127,858,198
Ensembl chr X:132,730,027...132,736,080

G

G protein-coupled receptor 137B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR137B mRNA

NCBI chr17:92,987,792...93,026,003
Ensembl chr17:92,942,559...93,025,911

G

G protein-coupled receptor 149

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR149 mRNA

NCBI chr 2:149,059,333...149,130,798
Ensembl chr 2:149,059,336...149,130,785

G

G protein-coupled receptor 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR15 mRNA

NCBI chr11:55,367,496...55,368,842
Ensembl chr11:55,358,614...55,374,150

G

G protein-coupled receptor 152

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR152 mRNA

NCBI chr 1:210,865,338...210,867,833
Ensembl chr 1:210,865,338...210,867,833

G

G protein-coupled receptor 17

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR17 mRNA

NCBI chr18:23,850,460...23,857,381
Ensembl chr18:23,850,107...23,857,702

G

G protein-coupled receptor 176

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR176 mRNA

NCBI chr 3:125,690,750...125,791,172
Ensembl chr 3:125,690,751...125,791,172

G

G protein-coupled receptor 20

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR20 mRNA

NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:107,490,713...107,500,966

G

G protein-coupled receptor 27

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR27 mRNA

NCBI chr 4:133,884,894...133,886,027
Ensembl chr 4:133,883,234...133,904,093

G

G protein-coupled receptor 37-like 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR37L1 mRNA

NCBI chr13:49,150,355...49,157,204
Ensembl chr13:49,150,359...49,157,204

G

G protein-coupled receptor 39

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR39 mRNA

NCBI chr13:39,667,908...39,879,944
Ensembl chr13:39,667,909...39,880,902

G

G protein-coupled receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR4 mRNA

NCBI chr 1:87,993,398...88,004,568
Ensembl chr 1:87,993,430...88,006,254

G

G protein-coupled receptor 50

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR50 mRNA

NCBI chr X:154,413,592...154,419,236
Ensembl chr X:154,413,689...154,418,275

G

G protein-coupled receptor 68

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GPR68 mRNA

NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:125,864,942...125,895,674

G

G protein-coupled receptor 83

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR83 mRNA

NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:19,974,993...19,985,490

G

G protein-coupled receptor 85

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR85 mRNA

NCBI chr 4:43,070,194...43,075,662
Ensembl chr 4:43,060,777...43,075,794

G

G-protein coupled receptor 88

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPR88 mRNA

NCBI chr 2:206,876,373...206,885,034
Ensembl chr 2:206,868,585...206,884,945

G

G protein-coupled receptor, class C, group 5, member B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPRC5B mRNA

NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757

G

G protein-coupled receptor, class C, group 5, member D

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPRC5D mRNA

NCBI chr 4:169,674,874...169,686,965
Ensembl chr 4:169,674,846...169,686,965

G

glutamic--pyruvic transaminase

decreases activity

ISO

Dextran Sulfate results in decreased activity of GPT protein

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutamic--pyruvic transaminase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of GPT2 mRNA

NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917

G

glutathione peroxidase 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GPX2 protein]

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione peroxidase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPX3 mRNA

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405

G

glutathione peroxidase 4

decreases expression
decreases activity
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GPX4 mRNA; Dextran Sulfate results in decreased expression of GPX4 protein
Dextran Sulfate results in decreased activity of GPX4 protein
[Azoxymethane co-treated with Dextran Sulfate] results in increased activity of GPX4 protein; gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of GPX4 mRNA]; gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of GPX4 protein]; sinpeinine A inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased activity of GPX4 protein]

PMID:36135333 PMID:39551424

NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629

G

glutathione peroxidase 6

decreases expression

ISO

Dextran Sulfate results in decreased expression of GPX6 mRNA

NCBI chr17:48,104,197...48,111,816
Ensembl chr17:48,104,197...48,111,007

G

glutathione peroxidase 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPX7 mRNA

NCBI chr 5:128,373,881...128,381,866
Ensembl chr 5:128,372,875...128,381,725

G

glutathione peroxidase 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GPX8 mRNA

NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:46,409,139...46,413,406

G

growth factor receptor bound protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRB2 mRNA

NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138

G

growth factor receptor bound protein 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GRB7 mRNA

NCBI chr10:83,936,538...83,949,344
Ensembl chr10:83,939,299...83,949,382

G

gremlin 1, DAN family BMP antagonist

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of GREM1 protein]

NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089

G

glutamate ionotropic receptor kainate type subunit 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRIK4 mRNA

NCBI chr 8:51,802,045...52,228,751
Ensembl chr 8:51,802,058...52,102,063

G

glutamate ionotropic receptor NMDA type subunit 2B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GRIN2B mRNA

NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570

G

glutamate ionotropic receptor NMDA type subunit 2D

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRIN2D mRNA

NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:105,444,813...105,481,236

G

G protein-coupled receptor kinase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRK3 mRNA

NCBI chr12:49,285,228...49,395,803
Ensembl chr12:49,285,263...49,395,802

G

G protein-coupled receptor kinase 6

multiple interactions
decreases response to substance

ISO

GRK6 mutant form promotes the reaction [Dextran Sulfate promotes the reaction [Capsaicin results in increased expression of FOS protein]]
GRK6 results in decreased susceptibility to Dextran Sulfate

NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,182,160...9,197,954

G

glutamate metabotropic receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GRM4 mRNA

NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,482,977...5,574,668

G

gastrin releasing peptide receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GRPR mRNA

NCBI chr X:34,630,238...34,670,245
Ensembl chr X:34,630,229...34,670,245

G

gasdermin D

multiple interactions
increases cleavage

ISO

hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein]

NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722

G

gelsolin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GSN mRNA

NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850

G

glutathione-disulfide reductase

decreases activity
multiple interactions

ISO

Dextran Sulfate results in decreased activity of GSR protein
Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in decreased activity of GSR protein]

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

glutathione S-transferase kappa 1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSTK1 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GSTK1 protein]

PMID:29950665 PMID:35362542

NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927

G

glutathione S-transferase mu 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of GSTM1 mRNA

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of GSTM2 mRNA

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase, mu 5

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of GSTM3 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GSTM3 protein]

PMID:32272095 PMID:35362542

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

glutathione S-transferase omega 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSTO1 mRNA

NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:256,662,531...256,676,167

G

glutathione S-transferase omega 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GSTO2 mRNA

NCBI chr 1:256,673,376...256,695,154
Ensembl chr 1:256,673,274...256,695,146

G

general transcription factor IIF subunit 1

increases expression

ISO

Dextran Sulfate results in increased expression of GTF2F1 mRNA

NCBI chr 9:1,931,033...1,940,197
Ensembl chr 9:1,930,055...1,940,197

G

guanylate cyclase activator 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GUCA1A mRNA

NCBI chr 9:21,080,782...21,096,221
Ensembl chr 9:21,086,642...21,096,221

G

guanylate cyclase activator 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GUCA1B mRNA

NCBI chr 9:21,097,274...21,105,107
Ensembl chr 9:21,097,274...21,105,107

G

guanylate cyclase activator 2B

increases expression

ISO

Dextran Sulfate results in increased expression of GUCA2B protein

NCBI chr 5:138,532,160...138,534,210
Ensembl chr 5:138,532,178...138,534,235

G

guanylate cyclase 2F

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of GUCY2F mRNA

NCBI chr X:110,507,183...110,605,017
Ensembl chr X:110,507,183...110,605,017

G

guanylate kinase 1

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of GUK1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of GUK1 protein]

PMID:32272095 PMID:35362542

NCBI chr10:44,471,075...44,488,332
Ensembl chr10:44,471,085...44,479,355

G

glycogenin 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of GYG1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of GYG1 protein]

NCBI chr 2:104,540,927...104,583,038
Ensembl chr 2:104,540,533...104,582,818

G

granzyme A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GZMA mRNA

NCBI chr 2:46,473,763...46,485,696
Ensembl chr 2:46,473,763...46,485,696

G

H1.1 linker histone, cluster member

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of H1F1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of H1F1 protein]

NCBI chr17:41,762,278...41,794,876

G

H1.10 linker histone

increases expression

ISO

Dextran Sulfate results in increased expression of H1F10 mRNA

NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of H6PD protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of H6PD protein]

NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:165,721,654...165,753,125

G

hydroxyacyl-CoA dehydrogenase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of HADH protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of HADH protein]

NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HADHB mRNA

NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835

G

hemoglobin alpha, adult chain 1

increases expression

ISO

Dextran Sulfate results in increased expression of HBA-A1 mRNA

NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603

G

hemoglobin subunit beta

increases expression

ISO

Dextran Sulfate results in increased expression of HBB-B1 mRNA

NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873

G

hemoglobin, beta adult minor chain

increases expression

ISO

Dextran Sulfate results in increased expression of HBB-B2 mRNA

NCBI chr 1:167,655,583...167,656,963

G

hematopoietic cell specific Lyn substrate 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of HCLS1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of HCLS1 protein]

NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387

G

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HCN2 mRNA

NCBI chr 7:10,620,422...10,639,457
Ensembl chr 7:10,620,422...10,639,457

G

hyperpolarization-activated cyclic nucleotide-gated potassium channel 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HCN3 mRNA

NCBI chr 2:176,849,635...176,867,726
Ensembl chr 2:176,849,635...176,868,538

G

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HCN4 mRNA

NCBI chr 8:68,118,062...68,155,482
Ensembl chr 8:68,118,062...68,155,495

G

HDGF like 2

increases expression

ISO

Dextran Sulfate results in increased expression of HDGFL2 mRNA

NCBI chr 9:996,687...1,016,352
Ensembl chr 9:996,758...1,016,735

G

hephaestin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HEPH mRNA

NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453

G

hes family bHLH transcription factor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of HES1 mRNA

NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061

G

hypoxia inducible factor 1 subunit alpha

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of HIF1A mRNA; Dextran Sulfate results in increased expression of HIF1A protein
Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of HIF1A protein]; xianglian pill inhibits the reaction [Dextran Sulfate results in increased expression of HIF1A mRNA]

PMID:26074695 PMID:33486267

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

histidine triad nucleotide binding protein 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of HINT2 protein]

NCBI chr 5:62,700,383...62,702,638
Ensembl chr 5:62,700,384...62,702,915

G

HIRA interacting protein 3

increases expression

ISO

Dextran Sulfate results in increased expression of HIRIP3 mRNA

NCBI chr 1:190,903,065...190,905,610
Ensembl chr 1:190,902,593...190,905,607

G

hexokinase 1

multiple interactions
increases expression

ISO

hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased expression of HK1 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of HK1 protein]

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

hexokinase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HK3 mRNA

NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037

G

high mobility group box 1

multiple interactions

ISO

Dextran Sulfate results in increased expression of and results in increased secretion of HMGB1 protein; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of HMGB1 protein]

NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327

G

high mobility group box 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of HMGB3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of HMGB3 protein]

NCBI chr X:154,341,106...154,346,087
Ensembl chr X:154,340,935...154,346,097

G

heme oxygenase 1

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HMOX1 mRNA; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; tussilagone inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]
Dextran Sulfate results in decreased expression of HMOX1 mRNA; Dextran Sulfate results in decreased expression of HMOX1 protein

PMID:29950665 PMID:30142311 PMID:33974900 PMID:36135333

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

HNF1 homeobox A

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of HNF1A protein
6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased expression of HNF1A protein]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HNF1A mRNA

PMID:29680209 PMID:29950665

NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755

G

HNF1 homeobox B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HNF1B mRNA

NCBI chr10:69,233,377...69,287,360
Ensembl chr10:69,233,131...69,287,361

G

hepatocyte nuclear factor 4, alpha

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HNF4A mRNA
Dextran Sulfate results in decreased expression of HNF4A mRNA

PMID:29950665 PMID:38844255

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758

G

hepatocyte nuclear factor 4, gamma

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HNF4G mRNA

NCBI chr 2:99,792,942...99,943,811
Ensembl chr 2:99,792,942...99,943,811

G

heterogeneous nuclear ribonucleoprotein A0

increases expression

ISO

Dextran Sulfate results in increased expression of HNRNPA0 mRNA

NCBI chr17:6,513,129...6,515,786
Ensembl chr17:6,512,629...6,516,127

G

heterogeneous nuclear ribonucleoprotein U-like 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of HNRNPUL1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of HNRNPUL1 protein]

NCBI chr 1:90,356,182...90,391,923
Ensembl chr 1:90,356,182...90,390,370

G

hook microtubule-tethering protein 2

increases expression

ISO

Dextran Sulfate results in increased expression of HOOK2 mRNA

NCBI chr19:40,056,732...40,075,027
Ensembl chr19:40,056,732...40,081,270

G

haptoglobin

multiple interactions
decreases expression
increases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of HP protein; Chlorpyrifos promotes the reaction [Dextran Sulfate results in increased expression of HP protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of HP protein]

PMID:31807802 PMID:35362542 PMID:35999755

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518

G

15-hydroxyprostaglandin dehydrogenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HPGD mRNA

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831

G

heparanase

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of HPSE protein

NCBI chr14:9,200,971...9,241,377
Ensembl chr14:9,188,275...9,241,754

G

histamine receptor H3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HRH3 mRNA

NCBI chr 3:187,569,174...187,575,263
Ensembl chr 3:187,569,175...187,574,259

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD11B1 mRNA
Dextran Sulfate results in increased expression of HSD11B1 mRNA

PMID:29950665 PMID:35093514

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HSD11B2 mRNA

NCBI chr19:50,307,569...50,312,812
Ensembl chr19:50,307,569...50,312,812

G

hydroxysteroid (17-beta) dehydrogenase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD17B1 mRNA

NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,510,011...86,512,210

G

hydroxysteroid (17-beta) dehydrogenase 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of HSD17B3 mRNA

NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,032,958...1,064,283

G

hydroxysteroid (17-beta) dehydrogenase 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HSD17B6 mRNA

NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of HSD3B1 mRNA

NCBI chr 2:188,858,574...188,864,694

G

heat shock protein 90 alpha family class A member 1

multiple interactions
increases expression

EXP
ISO

celastrol inhibits the reaction [Dextran Sulfate results in increased expression of HSP90AA1 mRNA]
xianglian pill inhibits the reaction [Dextran Sulfate results in increased expression of HSP90AA1 mRNA]

PMID:32470352 PMID:33486267

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein 90 alpha family class B member 1

multiple interactions
increases expression

EXP

celastrol inhibits the reaction [Dextran Sulfate results in increased expression of HSP90AB1 protein]

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of HSPA1A mRNA

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1B

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in decreased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 8

decreases expression

ISO

Dextran Sulfate results in decreased expression of HSPA8 protein

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family B (small) member 1

multiple interactions
increases expression

ISO

Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of HSPB1 mRNA]

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heparan sulfate proteoglycan 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSPG2 mRNA

NCBI chr 5:154,960,818...155,061,971
Ensembl chr 5:154,960,846...155,061,971

G

5-hydroxytryptamine receptor 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HTR1B mRNA

NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:91,052,432...91,418,583

G

5-hydroxytryptamine receptor 1D

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of HTR1D mRNA

NCBI chr 5:153,939,735...153,960,012
Ensembl chr 5:153,939,516...153,960,012

G

5-hydroxytryptamine receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of HTR4 mRNA

NCBI chr18:58,036,277...58,221,327
Ensembl chr18:58,036,277...58,219,622

G

5-hydroxytryptamine receptor 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HTR7 mRNA

NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230

G

HtrA serine peptidase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of HTRA1 mRNA

NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620

G

intercellular adhesion molecule 1

multiple interactions
increases expression

ISO

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ICAM1 mRNA; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA]

PMID:21724996 PMID:24038091 PMID:25448682 PMID:25472953 PMID:29950665 More...

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

intercellular adhesion molecule 4, Landsteiner-Wiener blood group

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ICAM4 mRNA

NCBI chr 8:27,842,255...27,843,351
Ensembl chr 8:27,842,255...27,844,371

G

inducible T-cell co-stimulator ligand

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ICOSL mRNA

NCBI chr20:10,600,078...10,610,385
Ensembl chr20:10,600,078...10,610,365

G

isocitrate dehydrogenase (NADP(+)) 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of IDH1 mRNA

NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555

G

indoleamine 2,3-dioxygenase 1

increases expression

ISO

Dextran Sulfate results in increased expression of IDO1 mRNA

NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328

G

immediate early response 3

multiple interactions
increases expression

ISO

Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IER3 mRNA]

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377

G

interferon induced transmembrane protein 3

multiple interactions
increases expression

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of IFITM3 mRNA; [Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of IFITM3 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IFITM3 protein]

PMID:26271895 PMID:32272095

NCBI chr 1:205,540,649...205,541,758
Ensembl chr 1:205,481,168...205,547,920

G

interferon, alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNA5 mRNA

NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809

G

interferon alpha and beta receptor subunit 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNAR2 mRNA

NCBI chr11:44,099,574...44,131,941
Ensembl chr11:44,099,753...44,131,937

G

interferon gamma

multiple interactions
increases expression
increases secretion

ISO

2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; 5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; [Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNG protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IFNG protein; [Dextran Sulfate affects the susceptibility to CD14 protein] which affects the expression of IFNG mRNA; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IFNG protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IFNG protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IFNG protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IFNG protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Coumarins inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFNG protein]; Lipopolysaccharides affects the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; MIF protein affects the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; PNU-282987 inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IFNG protein]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of IFNG protein]
Dextran Sulfate results in increased expression of IFNG mRNA; Dextran Sulfate results in increased expression of IFNG protein

PMID:12105854 PMID:19940103 PMID:20637373 PMID:21068411 PMID:21359540 More...

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon kappa

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IFNK mRNA

NCBI chr 5:54,528,304...54,530,511
Ensembl chr 5:54,528,304...54,530,511

G

insulin-like growth factor 1

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IGF1 protein

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764

G

insulin-like growth factor 2 mRNA binding protein 3

multiple interactions

ISO

[Dextran Sulfate co-treated with azomethane] results in increased expression of IGF2BP3 protein; Berberine inhibits the reaction [[Dextran Sulfate co-treated with azomethane] results in increased expression of IGF2BP3 protein]

NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730

G

insulin-like growth factor 2 receptor

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of IGF2R protein]

NCBI chr 1:50,526,878...50,615,265
Ensembl chr 1:50,526,878...50,615,265

G

insulin-like growth factor binding protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IGFBP2 mRNA

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171

G

insulin-like growth factor binding protein 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IGFBP4 mRNA

NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473

G

insulin-like growth factor binding protein 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IGFBP6 mRNA

NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795

G

insulin-like growth factor binding protein 7

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of IGFBP7 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of IGFBP7 protein]

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620

G

Indian hedgehog signaling molecule

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IHH mRNA

NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203

G

IK cytokine

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of IK protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of IK protein]

NCBI chr18:28,632,025...28,646,829
Ensembl chr18:28,631,616...28,653,463

G

inhibitor of nuclear factor kappa B kinase subunit beta

multiple interactions
increases expression
increases activity

ISO

3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased activity of IKBKB protein]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IKBKB mRNA; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IKBKB protein modified form]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of IKBKB protein]

PMID:20155626 PMID:25472953 PMID:29950665

NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

increases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of IKBKE protein
GW 506033X inhibits the reaction [Dextran Sulfate results in increased phosphorylation of IKBKE protein]

NCBI chr13:45,264,404...45,290,737
Ensembl chr13:45,264,412...45,289,396

G

IKAROS family zinc finger 3

increases expression

ISO

Dextran Sulfate results in increased expression of IKZF3 mRNA

NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861

G

interleukin 10

multiple interactions
decreases expression
increases expression

ISO
EXP

2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester promotes the reaction [Dextran Sulfate results in increased expression of IL10 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL10 protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL10 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL10 protein; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; celastrol inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; Chlorpyrifos inhibits the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; Coumarins inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein; flavokawain B inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL10 protein]; huanglian-jie-du decoction inhibits the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL10 protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 mRNA]; Lipopolysaccharides affects the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]; Nicotine inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; Resveratrol promotes the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]
Dextran Sulfate results in decreased expression of IL10 mRNA; Dextran Sulfate results in decreased expression of IL10 protein
Dextran Sulfate results in increased expression of IL10 mRNA; Dextran Sulfate results in increased expression of IL10 protein
kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL10 mRNA]

PMID:20132809 PMID:20881082 PMID:21068411 PMID:21359540 PMID:21724996 More...

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL11 mRNA; Melatonin inhibits the reaction [Dextran Sulfate results in decreased expression of IL11 protein]

PMID:29950665 PMID:36265525

NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915

G

interleukin 11 receptor subunit alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL11RA1 mRNA

NCBI chr 5:61,727,650...61,737,265
Ensembl chr 5:61,727,931...61,737,264

G

interleukin 12A

affects response to substance

ISO

IL12A protein affects the susceptibility to Dextran Sulfate

NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997

G

interleukin 12B

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of IL12B mRNA
ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL12B mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL12B mRNA]

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194

G

interleukin 15

increases response to substance
multiple interactions
decreases expression

ISO
EXP

IL15 protein results in increased susceptibility to Dextran Sulfate
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL15 mRNA
Oligosaccharides inhibits the reaction [Dextran Sulfate results in decreased expression of IL15 mRNA]

PMID:16162679 PMID:16375993 PMID:29950665

NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348

G

interleukin 17A

multiple interactions
affects response to substance
increases expression

ISO
EXP

2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; 5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IFNG protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL17A mRNA; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL17A protein]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]]; xianglian pill inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]
Dextran Sulfate results in increased expression of IL17A mRNA; Dextran Sulfate results in increased expression of IL17A protein
kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL17A mRNA]

PMID:20881082 PMID:21068411 PMID:24384223 PMID:24548422 PMID:26074695 More...

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331

G

interleukin 18

affects response to substance
multiple interactions
increases expression
increases secretion

ISO
EXP

IL18 protein affects the susceptibility to Dextran Sulfate
celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; celastrol promotes the reaction [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide promotes the reaction [celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]]
Dextran Sulfate results in increased secretion of IL18 protein
[Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL18 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL18 mRNA; biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; Dextran Sulfate inhibits the reaction [Zearalenone results in increased secretion of IL18 protein]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein]
Dextran Sulfate results in increased expression of IL18 mRNA; Dextran Sulfate results in increased expression of IL18 protein

PMID:12940437 PMID:25448682 PMID:29950665 PMID:30270565 PMID:32470352 More...

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 18 receptor 1

affects response to substance

ISO

IL18R1 protein affects the susceptibility to Dextran Sulfate

NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:50,223,200...50,257,367

G

interleukin 18 receptor accessory protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL18RAP mRNA

NCBI chr 9:50,263,723...50,296,583
Ensembl chr 9:50,263,733...50,296,583

G

interleukin 19

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL19 mRNA

NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714

G

interleukin 1 alpha

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of IL1A mRNA; Dextran Sulfate results in increased expression of IL1A protein
2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL1A protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1A protein; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL1A protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1A mRNA]

PMID:23894361 PMID:25472953 PMID:29672155 PMID:34273909 PMID:36265525

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

multiple interactions
increases expression
increases cleavage
increases secretion

ISO
EXP

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; 3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]; [ABTB1 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of IL1B protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of IL1B protein; [HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL1B mRNA; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL1B protein]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Allura Red AC Dye promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; CEP 33779 inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of IL1B protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; Coumarins inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; daphnetin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]]; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; gingerenone A inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; Granisetron inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; GW 506033X inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased cleavage of IL1B protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; isomaltulose inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; isovitexin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased cleavage of IL1B protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Nicotine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; nuciferine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; oxymatrine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; phenethyl isothiocyanate inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Quercetin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of IL1B protein]
Dextran Sulfate results in increased expression of IL1B mRNA; Dextran Sulfate results in increased expression of IL1B protein
[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1B protein; banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; celastrol promotes the reaction [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1B protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]

PMID:15652231 PMID:16774945 PMID:19028472 PMID:19285099 PMID:19645018 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor type 1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL1R1 mRNA; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL1R1 mRNA]

PMID:29950665 PMID:32033881

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579

G

interleukin 1 receptor type 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL1R2 mRNA

NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374

G

interleukin 1 receptor antagonist

multiple interactions
decreases expression

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN protein; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of IL1RN protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL1RN protein]

PMID:25026504 PMID:35362542

NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732

G

interleukin 2

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of IL2 mRNA; Dextran Sulfate results in increased expression of IL2 protein
Dextran Sulfate results in decreased expression of IL2 protein
5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA]; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of IL2 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of IL2 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL2 mRNA]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased expression of IL2 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL2 protein]

PMID:21068411 PMID:25472953 PMID:32272095 PMID:35362542 PMID:35889507

NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672

G

interleukin 20 receptor subunit alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL20RA mRNA

NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:16,243,801...16,313,221

G

interleukin 20 receptor subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL20RB mRNA

NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363

G

interleukin 22 receptor subunit alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL22RA1 mRNA

NCBI chr 5:153,245,067...153,269,865
Ensembl chr 5:153,245,002...153,271,683

G

interleukin 22 receptor subunit alpha 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of IL22RA2 mRNA

NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950

G

interleukin 23 subunit alpha

increases expression
multiple interactions

ISO
EXP

Dextran Sulfate results in increased expression of IL23A protein
kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL23A mRNA]
celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL23A protein]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL23A protein]

PMID:20881082 PMID:24384223 PMID:36265525

NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434

G

interleukin 27 receptor subunit alpha

decreases response to substance

ISO

IL27RA protein results in decreased susceptibility to Dextran Sulfate

NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760

G

interleukin 2 receptor subunit gamma

increases expression

ISO

Dextran Sulfate results in increased expression of IL2RG mRNA

NCBI chr X:70,435,340...70,439,052
Ensembl chr X:70,435,343...70,439,161

G

interleukin 33

multiple interactions
increases expression

ISO

flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of IL33 mRNA]

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901

G

interleukin 3 receptor subunit alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL3RA mRNA

NCBI chr12:21,431,848...21,437,336
Ensembl chr12:21,431,848...21,437,250

G

interleukin 4

decreases expression
increases expression
multiple interactions

ISO
EXP

Dextran Sulfate results in decreased expression of IL4 mRNA
Dextran Sulfate results in increased expression of IL4 protein
[TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL4 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL4 protein; MIF protein affects the reaction [Dextran Sulfate results in decreased expression of IL4 mRNA]

PMID:12105854 PMID:21068411 PMID:25777935 PMID:28438436

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

interleukin 4 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL4RA mRNA

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636

G

interleukin 6

multiple interactions
increases secretion
affects expression
increases expression

ISO
EXP

(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; 4-methylesculetin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased secretion of IL6 protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of IL6 protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased secretion of IL6 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 protein]; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Allura Red AC Dye promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased secretion of IL6 protein]; asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Benzo(a)pyrene inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; CEP 33779 inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of IL6 protein]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Coumarins inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; daphnetin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Dextran Sulfate affects the reaction [TLR4 protein affects the expression of IL6 protein]; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of IL6 protein]; Dextran Sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Dextran Sulfate inhibits the reaction [Polymyxin B results in decreased expression of IL6 protein]; Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; gingerenone A inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; Granisetron inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; GW 506033X inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; huanglian-jie-du decoction inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of IL6 protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL6 protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Lipopolysaccharides affects the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Lipopolysaccharides promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of IL6 protein]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; Nicotine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; oxymatrine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; PNU-282987 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased secretion of IL6 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]
Dextran Sulfate results in increased expression of IL6 mRNA; Dextran Sulfate results in increased expression of IL6 protein
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; celastrol promotes the reaction [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]

PMID:15652231 PMID:16774945 PMID:19285099 PMID:19940103 PMID:20079348 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 cytokine family signal transducer

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL6ST mRNA

NCBI chr 2:45,798,872...45,839,501
Ensembl chr 2:45,799,380...45,843,182

G

interleukin 7 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IL7R mRNA

NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027

G

integrin-linked kinase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ILK protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of ILK protein

NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:169,498,681...169,506,964

G

inhibin subunit beta A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INHBA mRNA

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

inhibin subunit beta B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INHBB mRNA

NCBI chr13:33,083,671...33,089,373
Ensembl chr13:33,083,671...33,089,609

G

INO80 complex subunit B

increases expression

ISO

Dextran Sulfate results in increased expression of INO80B mRNA

NCBI chr 4:117,185,427...117,188,930
Ensembl chr 4:117,185,620...117,189,168

G

inositol polyphosphate-5-phosphatase D

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INPP5D mRNA

NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589

G

insulin like 5

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INSL5 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of INSL5 protein]

PMID:29950665 PMID:32272095

NCBI chr 5:117,773,104...117,777,376

G

IQ motif and ankyrin repeat containing 1

increases expression

ISO

Dextran Sulfate results in increased expression of IQANK1 mRNA

NCBI chr 7:109,605,642...109,639,854
Ensembl chr 7:109,605,703...109,639,853

G

IQ motif containing D

increases expression

ISO

Dextran Sulfate results in increased expression of IQCD mRNA

NCBI chr12:41,616,107...41,633,244
Ensembl chr12:41,616,107...41,623,352

G

inositol 1,4,5-triphosphate receptor associated 1

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of IRAG1 protein]

NCBI chr 1:174,416,383...174,528,913
Ensembl chr 1:174,416,385...174,528,851

G

interleukin-1 receptor-associated kinase 1

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of IRAK1 protein

NCBI chr X:156,919,927...156,929,825
Ensembl chr X:156,920,081...156,929,825

G

interleukin-1 receptor-associated kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IRAK2 mRNA

NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210

G

interleukin-1 receptor-associated kinase 4

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of IRAK4 protein

NCBI chr 7:127,561,777...127,588,762
Ensembl chr 7:127,561,717...127,597,109

G

interferon regulatory factor 4

multiple interactions

ISO

IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of CD86 protein]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of and results in decreased secretion of IL10 protein]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of ARG1 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of ARG1 protein]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of CD86 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of CD86 protein]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of TNF mRNA]

NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,930,471...33,948,730

G

insulin receptor substrate 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IRS1 mRNA

NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538

G

iroquois homeobox 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IRX6 mRNA

NCBI chr19:30,503,416...30,509,396
Ensembl chr19:30,503,419...30,509,382

G

integrin subunit alpha 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ITGA10 mRNA

NCBI chr 2:186,871,711...186,891,012
Ensembl chr 2:186,871,711...186,891,012

G

integrin subunit alpha 2b

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA2B mRNA

NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,908,697...87,925,833

G

integrin subunit alpha 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA4 mRNA

NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039

G

integrin subunit alpha 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA5 mRNA

NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305

G

integrin subunit alpha 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGA6 mRNA

NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076

G

integrin subunit alpha L

multiple interactions
increases expression

ISO

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA]

NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225

G

integrin subunit beta 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGB1 mRNA

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269

G

integrin subunit beta 2

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGB2 mRNA; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ITGB2 protein]

PMID:29950665 PMID:32272095

NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182

G

integrin subunit beta 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGB3 mRNA

NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800

G

integrin subunit beta 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ITGB6 mRNA

NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333

G

integrin subunit beta 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ITGB8 mRNA

NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:146,165,484...146,351,245

G

inter-alpha trypsin inhibitor, heavy chain 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ITIH1 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ITIH1 protein]

NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853

G

inter-alpha trypsin inhibitor, heavy chain 3

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of ITIH3 protein

NCBI chr16:6,108,378...6,123,609
Ensembl chr16:6,108,382...6,123,374

G

inter-alpha-trypsin inhibitor heavy chain 4

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ITIH4 protein
Dextran Sulfate results in decreased expression of ITIH4 protein
[Dextran Sulfate co-treated with bisphenol A] results in increased expression of ITIH4 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of ITIH4 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ITIH4 protein]

PMID:32272095 PMID:35362542 PMID:35999755

NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160

G

inter-alpha-trypsin inhibitor heavy chain 5

decreases expression

ISO

Dextran Sulfate results in decreased expression of ITIH5 mRNA

NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496

G

inositol-trisphosphate 3-kinase A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ITPKA mRNA

NCBI chr 3:127,179,841...127,188,405
Ensembl chr 3:127,179,808...127,188,414

G

inositol 1,4,5-trisphosphate receptor, type 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ITPR3 mRNA

NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184

G

Janus kinase 2

increases phosphorylation
increases expression
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of JAK2 protein
Dextran Sulfate results in increased expression of JAK2 mRNA
BCL6 protein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; Dextran Sulfate results in increased expression of and results in increased phosphorylation of JAK2 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; fucoxanthin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of JAK2 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased phosphorylation of JAK2 protein]; xianglian pill inhibits the reaction [Dextran Sulfate results in increased expression of JAK2 mRNA]

PMID:32272095 PMID:33486267 PMID:38164749 PMID:38437956 PMID:38663798 More...

NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762

G

junctional adhesion molecule 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAM2 mRNA

NCBI chr11:37,316,287...37,366,517
Ensembl chr11:37,317,511...37,367,510

G

junctional adhesion molecule 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAM3 mRNA

NCBI chr 8:33,767,606...33,828,451
Ensembl chr 8:33,767,607...33,828,623

G

junction adhesion molecule like

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of JAML mRNA

NCBI chr 8:54,281,596...54,313,655
Ensembl chr 8:54,281,644...54,313,500

G

joining chain of multimeric IgA and IgM

decreases expression

ISO

Dextran Sulfate results in decreased expression of JCHAIN mRNA

NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,822,976...19,838,307

G

Josephin domain containing 2

increases expression

ISO

Dextran Sulfate results in increased expression of JOSD2 mRNA

NCBI chr 1:104,097,382...104,101,271
Ensembl chr 1:104,097,376...104,101,277

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

Dextran Sulfate results in increased expression of and affects the localization of JUN protein; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of JUN protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of JUN protein]

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

kalirin, RhoGEF kinase

decreases expression

ISO

Dextran Sulfate results in decreased expression of KALRN protein

NCBI chr11:79,703,345...80,309,210
Ensembl chr11:79,703,366...80,133,329

G

KASH domain containing 5

increases expression

ISO

Dextran Sulfate results in increased expression of KASH5 mRNA

NCBI chr 1:104,805,248...104,827,720
Ensembl chr 1:104,804,535...104,827,802

G

potassium voltage-gated channel subfamily A regulatory beta subunit 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of KCNAB1 mRNA

NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:151,446,947...151,913,636

G

potassium voltage-gated channel subfamily E regulatory subunit 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KCNE3 mRNA

NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:163,935,991...163,950,162

G

potassium voltage-gated channel subfamily H member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of KCNH2 mRNA

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421

G

potassium inwardly-rectifying channel, subfamily J, member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of KCNJ9 mRNA

NCBI chr13:87,313,191...87,320,293
Ensembl chr13:87,312,378...87,320,293

G

potassium two pore domain channel subfamily K member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of KCNK4 mRNA

NCBI chr 1:213,547,577...213,558,706
Ensembl chr 1:213,547,577...213,555,861

G

potassium two pore domain channel subfamily K member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KCNK5 mRNA

NCBI chr15:4,171,625...4,213,896
Ensembl chr15:4,171,610...4,213,897

G

lysine demethylase 1A

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of KDM1A protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of KDM1A protein]

NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:154,065,543...154,121,775

G

KiSS-1 metastasis-suppressor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KISS1 mRNA

NCBI chr13:47,327,159...47,332,759
Ensembl chr13:47,327,004...47,332,906

G

KIT proto-oncogene receptor tyrosine kinase

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KIT mRNA
Dextran Sulfate results in decreased expression of KIT mRNA

PMID:29950665 PMID:35093514

NCBI chr14:32,901,615...32,978,895
Ensembl chr14:32,903,033...32,978,812

G

KIT ligand

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KITL mRNA

NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793

G

klotho beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of KLB mRNA

NCBI chr14:43,253,963...43,304,532
Ensembl chr14:43,253,255...43,304,515

G

kinesin light chain 3

increases expression

ISO

Dextran Sulfate results in increased expression of KLC3 mRNA

NCBI chr 1:88,173,842...88,183,806
Ensembl chr 1:88,173,404...88,184,253

G

kallikrein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KLK1 mRNA

NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270

G

kallikrein 1-related peptidase B3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KLK1B3 mRNA

NCBI chr 1:103,845,647...103,849,854
Ensembl chr 1:103,845,603...103,849,855

G

kallikrein 1-related peptidase C10

multiple interactions

ISO

Dextran Sulfate affects the reaction [SEMG2 protein binds to KLK3 protein]

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586

G

karyopherin subunit alpha 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of KPNA1 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of KPNA1 protein]

NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067

G

KRAS proto-oncogene, GTPase

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KRAS mRNA; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of KRAS protein]

PMID:29950665 PMID:32272095

NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320

G

keratin 16

decreases expression

ISO

Dextran Sulfate results in decreased expression of KRT16 protein

NCBI chr10:85,669,276...85,672,211
Ensembl chr10:85,669,276...85,672,211

G

L1 cell adhesion molecule

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of L1CAM mRNA
Dextran Sulfate results in decreased expression of L1CAM protein

PMID:29950665 PMID:35999755

NCBI chr X:156,748,597...156,775,116
Ensembl chr X:156,748,597...156,775,077

G

laminin subunit alpha 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LAMA5 mRNA

NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:187,647,904...187,696,173

G

laminin subunit beta 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LAMB2 mRNA

NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090

G

laminin subunit beta 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LAMB3 mRNA

NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081

G

laminin subunit gamma 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LAMC1 mRNA

NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986

G

laminin subunit gamma 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of LAMC3 mRNA

NCBI chr 3:35,562,989...35,624,460
Ensembl chr 3:35,562,713...35,624,460

G

lysosomal-associated membrane protein 2

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LAMP2 protein]

NCBI chr X:122,038,734...122,087,745
Ensembl chr X:121,922,187...122,087,675

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of LAMTOR2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LAMTOR2 protein]

NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:176,306,280...176,310,730

G

lysosomal protein transmembrane 5

increases expression

ISO

Dextran Sulfate results in increased expression of LAPTM5 mRNA

NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927

G

La ribonucleoprotein 1, translational regulator

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of LARP1 protein]

NCBI chr10:42,691,833...42,746,816
Ensembl chr10:42,691,600...42,746,816

G

LIM and SH3 protein 1

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of LASP1 protein
Dextran Sulfate results in decreased expression of LASP1 protein

NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988

G

linker for activation of T cells family, member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LAT2 mRNA

NCBI chr12:27,740,647...27,754,760
Ensembl chr12:27,740,654...27,755,843

G

layilin

decreases expression

ISO

Dextran Sulfate results in decreased expression of LAYN protein

NCBI chr 8:60,261,325...60,280,797
Ensembl chr 8:60,263,456...60,281,418

G

lipocalin 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of LCN2 mRNA; Dextran Sulfate results in increased expression of LCN2 protein
AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of LCN2 mRNA]; Allura Red AC Dye promotes the reaction [Dextran Sulfate results in increased expression of LCN2 protein]

PMID:23894361 PMID:36519841 PMID:36539404

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842

G

lactase

decreases activity
multiple interactions

ISO

Dextran Sulfate results in decreased activity of LCT protein
Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in decreased activity of LCT protein]

NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872

G

lactate dehydrogenase A

decreases expression

ISO

Dextran Sulfate results in decreased expression of LDHA protein

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

lactate dehydrogenase A-like 6B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LDHAL6B mRNA

NCBI chr 1:48,402,997...48,404,420
Ensembl chr 1:48,403,012...48,404,851

G

lactate dehydrogenase B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LDHB mRNA

NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408

G

lactate dehydrogenase C

increases activity
multiple interactions

ISO

Dextran Sulfate results in increased activity of LDHC protein
gingerol inhibits the reaction [Dextran Sulfate results in increased activity of LDHC protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased activity of LDHC protein]

NCBI chr 1:106,522,140...106,539,649
Ensembl chr 1:106,522,236...106,542,802

G

lymphoid enhancer binding factor 1

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LEF1 mRNA; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LEF1 protein; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LEF1 mRNA]; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LEF1 protein]

NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929

G

leukocyte receptor cluster member 1

increases expression

ISO

Dextran Sulfate results in increased expression of LENG1 mRNA

NCBI chr 1:74,467,343...74,472,275
Ensembl chr 1:74,467,326...74,472,280

G

leptin

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LEP mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LEP protein

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

legumain

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of LGMN protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LGMN protein]

NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328

G

leucine-rich repeat-containing G protein-coupled receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LGR4 mRNA

NCBI chr 3:116,901,968...117,004,584
Ensembl chr 3:116,901,968...117,004,153

G

leucine-rich repeat-containing G protein-coupled receptor 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LGR6 mRNA

NCBI chr13:48,976,193...49,095,870
Ensembl chr13:48,976,193...49,095,857

G

luteinizing hormone subunit beta

multiple interactions
decreases expression

ISO

gingerol inhibits the reaction [Dextran Sulfate results in decreased expression of LHB protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in decreased expression of LHB protein]

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of LHCGR mRNA
Dextran Sulfate results in decreased expression of LHCGR mRNA

PMID:29950665 PMID:35093514

NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:11,415,415...11,478,061

G

LIM domain kinase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LIMK1 mRNA

NCBI chr12:27,663,177...27,697,085
Ensembl chr12:27,663,018...27,697,209

G

LIM zinc finger domain containing 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of LIMS1 protein

NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,852,996...26,961,606

G

lamin B2

increases expression

ISO

Dextran Sulfate results in increased expression of LMNB2 mRNA

NCBI chr 7:9,443,308...9,459,468
Ensembl chr 7:9,440,128...9,459,342

G

lysyl oxidase

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LOX mRNA; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of LOX mRNA]

PMID:29950665 PMID:32033881 PMID:35093514

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

lysyl oxidase-like 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LOXL1 mRNA

NCBI chr 8:67,587,636...67,612,224
Ensembl chr 8:67,587,636...67,612,224

G

lysophosphatidic acid receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LPAR2 mRNA

NCBI chr16:19,625,974...19,633,905
Ensembl chr16:19,625,983...19,633,905

G

lysophosphatidic acid receptor 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LPAR3 mRNA

NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197

G

lysophosphatidic acid receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LPAR4 mRNA

NCBI chr X:76,106,319...76,119,807
Ensembl chr X:76,106,071...76,119,808

G

leucine-rich alpha-2-glycoprotein 1

increases expression

ISO

Dextran Sulfate results in increased expression of LRG1 mRNA

PMID:23894361 PMID:35093514

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337

G

LDL receptor related protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of LRP1 mRNA

NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196

G

LDL receptor related protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LRP2 mRNA

NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535

G

LDL receptor related protein 5

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LRP5 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of LRP5 mRNA]

NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822

G

LDL receptor related protein associated protein 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of LRPAP1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LRPAP1 protein]

NCBI chr14:79,876,002...79,888,011
Ensembl chr14:79,875,708...79,890,034

G

leucine rich repeat containing 61

increases expression

ISO

Dextran Sulfate results in increased expression of LRRC61 mRNA

NCBI chr 4:78,834,783...78,854,810
Ensembl chr 4:78,833,857...78,868,931

G

LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of LSM3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LSM3 protein]

NCBI chr 4:125,578,185...125,584,429
Ensembl chr 4:125,578,185...125,584,429

G

LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of LSM4 mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of LSM4 protein]

PMID:35093514 PMID:35362542

NCBI chr16:18,789,466...18,795,164
Ensembl chr16:18,789,467...18,794,886

G

lymphotoxin alpha

increases expression

ISO

Dextran Sulfate results in increased expression of LTA mRNA

NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533

G

leukotriene A4 hydrolase

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of LTA4H protein

NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641

G

leukotriene B4 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LTB4R1 mRNA

NCBI chr15:33,233,120...33,235,636
Ensembl chr15:33,232,820...33,235,637

G

latent transforming growth factor beta binding protein 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LTBP3 mRNA

NCBI chr 1:212,458,362...212,475,302
Ensembl chr 1:212,459,185...212,475,302

G

latent transforming growth factor beta binding protein 4

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LTBP4 mRNA
Dextran Sulfate results in decreased expression of LTBP4 mRNA

PMID:29950665 PMID:35093514

NCBI chr 1:91,727,769...91,759,822
Ensembl chr 1:91,727,769...91,760,006

G

lactotransferrin

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of LTF protein
Dextran Sulfate results in decreased expression of LTF protein

NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:119,878,344...119,901,189

G

LUC7 pre-mRNA splicing factor like 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of LUC7L3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of LUC7L3 protein]

NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429

G

lymphocyte antigen 6 family member D

decreases expression

ISO

Dextran Sulfate results in decreased expression of LY6D mRNA

NCBI chr 7:108,532,207...108,533,943
Ensembl chr 7:108,532,215...108,533,716

G

lymphocyte antigen 6 family member E

decreases expression

ISO

Dextran Sulfate results in decreased expression of LY6E mRNA

NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443

G

lymphocyte antigen 86

increases expression

ISO

Dextran Sulfate results in increased expression of LY86 mRNA

NCBI chr17:27,621,313...27,705,336
Ensembl chr17:27,621,313...27,692,743

G

lysozyme 2

increases expression

ISO

Dextran Sulfate results in increased expression of LYZ2 mRNA

NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011

G

microtubule-actin crosslinking factor 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MACF1 protein]

NCBI chr 5:140,908,829...141,234,127
Ensembl chr 5:140,908,837...141,233,890

G

MAF bZIP transcription factor F

increases expression

ISO

Dextran Sulfate results in increased expression of MAFF mRNA

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

myelin-associated glycoprotein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MAG mRNA

NCBI chr 1:95,275,728...95,291,133
Ensembl chr 1:95,275,635...95,291,060

G

mannosidase, alpha, class 1A, member 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MAN1A protein]

NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584

G

mesencephalic astrocyte-derived neurotrophic factor

decreases expression

ISO

Dextran Sulfate results in decreased expression of MANF protein

NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:116,427,048...116,429,910

G

monoamine oxidase A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MAOA mRNA

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]; [Dextran Sulfate co-treated with 6-formylindolo(3,2-b)carbazole] results in increased expression of and results in increased lipidation of MAP1LC3B protein; [Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in increased expression of and results in increased lipidation of MAP1LC3B protein]

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358

G

mitogen activated protein kinase kinase kinase 7

multiple interactions
increases phosphorylation

ISO

flavokawain B inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAP3K7 protein]

NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation
increases activity

ISO
EXP

3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased activity of MAPK1 protein]; 5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of MAPK1 protein; biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MAPK1 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]

PMID:19931517 PMID:20155626 PMID:35889507 PMID:36577154 PMID:36806191 More...

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MAPK10 mRNA

NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100

G

mitogen-activated protein kinase 11

multiple interactions
increases phosphorylation

ISO

formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK11 protein]

NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038

G

mitogen-activated protein kinase 12

increases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of MAPK12 protein
formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK12 protein]

NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307

G

mitogen activated protein kinase 13

increases expression
increases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased expression of MAPK13 protein
Dextran Sulfate results in increased phosphorylation of MAPK13 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MAPK13 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK13 protein]

PMID:35362542 PMID:39855309

NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191

G

mitogen activated protein kinase 14

increases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of MAPK14 protein
formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK14 protein]

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation
increases activity

ISO
EXP

3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased activity of MAPK3 protein]; 5,7-dimethoxycoumarin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of MAPK3 protein; biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MAPK3 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]

PMID:19931517 PMID:20155626 PMID:35889507 PMID:36577154 PMID:36806191 More...

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

ISO

formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

microtubule-associated protein, RP/EB family, member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of MAPRE1 protein

NCBI chr 3:162,679,020...162,707,167
Ensembl chr 3:162,673,195...162,711,210

G

MBL associated serine protease 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MASP1 mRNA

NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470

G

matrilin 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MATN4 mRNA

NCBI chr 3:173,539,966...173,554,984
Ensembl chr 3:173,539,966...173,554,984

G

mitochondrial antiviral signaling protein

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of MAVS protein]

NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:138,904,771...138,919,126

G

methyl-CpG binding domain protein 3

increases expression

ISO

Dextran Sulfate results in increased expression of MBD3 mRNA

NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,963,797...9,970,265

G

melanocortin 4 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MC4R mRNA

NCBI chr18:62,689,798...62,691,685

G

minichromosome maintenance complex component 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MCM3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MCM3 protein]

PMID:20025956 PMID:35362542

NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746

G

malate dehydrogenase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of MDH1 protein

NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232

G

midkine

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MDK mRNA

NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743

G

malic enzyme 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of ME1 protein

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275

G

mitochondrial trans-2-enoyl-CoA reductase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MECR protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MECR protein]

NCBI chr 5:149,313,765...149,339,964
Ensembl chr 5:149,313,774...149,342,825

G

mediator of cell motility 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MEMO1 protein]

NCBI chr 6:26,895,497...26,986,248
Ensembl chr 6:26,896,290...26,986,442

G

meprin A subunit alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MEP1A mRNA

NCBI chr 9:24,971,901...25,001,414
Ensembl chr 9:24,971,886...25,001,414

G

meprin A subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MEP1B mRNA

NCBI chr18:12,641,041...12,667,759
Ensembl chr18:12,641,041...12,667,755

G

mesoderm posterior bHLH transcription factor 1

increases expression

ISO

Dextran Sulfate results in increased expression of MESP1 mRNA

NCBI chr 1:143,147,671...143,149,189
Ensembl chr 1:143,147,671...143,149,189

G

microfibril associated protein 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MFAP4 mRNA

NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740

G

microfibril associated protein 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MFAP5 mRNA

NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:157,395,597...157,422,448

G

milk fat globule EGF and factor V/VIII domain containing

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of MFGE8 mRNA

NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression
decreases expression

ISO

Dextran Sulfate results in increased expression of MFSD2A mRNA
Dextran Sulfate results in decreased expression of MFSD2A mRNA

PMID:23894361 PMID:35093514

NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916

G

MGAT4 family, member C

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MGAT4C protein]

NCBI chr 7:38,596,117...39,361,103
Ensembl chr 7:38,596,065...39,362,078

G

matrix Gla protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MGP mRNA

NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859

G

microsomal glutathione S-transferase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MGST2 mRNA

NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661

G

microsomal glutathione S-transferase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MGST3 mRNA

NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575

G

mitochondrial calcium uptake 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MICU2 protein]

NCBI chr15:36,180,413...36,262,429
Ensembl chr15:36,170,832...36,262,686

G

migration and invasion enhancer 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MIEN1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MIEN1 protein]

NCBI chr10:83,931,485...83,932,778
Ensembl chr10:83,930,955...83,932,778

G

macrophage migration inhibitory factor

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MIF mRNA
MIF protein affects the reaction [Dextran Sulfate results in decreased expression of IL4 mRNA]; MIF protein affects the reaction [Dextran Sulfate results in increased expression of IFNG mRNA]; MIF protein affects the reaction [Dextran Sulfate results in increased expression of MMP13 mRNA]; MIF protein affects the reaction [Dextran Sulfate results in increased expression of TNF mRNA]

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

myo-inositol oxygenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MIOX mRNA

NCBI chr 7:122,284,660...122,287,158
Ensembl chr 7:122,284,660...122,287,157

G

marker of proliferation Ki-67

multiple interactions
decreases expression

EXP
ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MKI67 protein; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MKI67 protein]
Dextran Sulfate results in decreased expression of MKI67 protein
[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MKI67 protein; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MKI67 protein; berberrubine inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MKI67 protein]; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of MKI67 protein]; sinpeinine A inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MKI67 protein]

PMID:19028472 PMID:34273909 PMID:37871880 PMID:38648921 PMID:39551424

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

mixed lineage kinase domain like pseudokinase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MLKL protein
dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of MLKL protein]

NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858

G

membrane metallo-endopeptidase

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MME mRNA
Dextran Sulfate results in decreased expression of MME mRNA

PMID:29950665 PMID:35093514

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463

G

matrix metallopeptidase 10

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MMP10 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP10 mRNA

PMID:20824662 PMID:29950665

NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613

G

matrix metallopeptidase 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP12 mRNA

NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478

G

matrix metallopeptidase 13

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP13 mRNA; MIF protein affects the reaction [Dextran Sulfate results in increased expression of MMP13 mRNA]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP13 mRNA]

PMID:12105854 PMID:19285099 PMID:20824662 PMID:23894361 PMID:29950665

NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105

G

matrix metallopeptidase 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP14 mRNA

NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893

G

matrix metallopeptidase 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MMP15 mRNA

NCBI chr19:9,669,506...9,691,000
Ensembl chr19:9,669,506...9,691,000

G

matrix metallopeptidase 19

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP19 mRNA

NCBI chr 7:1,805,732...1,814,054
Ensembl chr 7:1,805,860...1,814,863

G

matrix metallopeptidase 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MMP2 mRNA; Dextran Sulfate results in increased expression of MMP2 protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP2 mRNA; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP2 mRNA]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP2 protein]

PMID:19285099 PMID:29950665

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 23

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP23 mRNA

NCBI chr 5:171,521,905...171,525,007
Ensembl chr 5:171,520,494...171,524,695

G

matrix metallopeptidase 3

multiple interactions
increases expression

ISO

Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP3 mRNA]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of MMP3 mRNA]

PMID:19285099 PMID:20824662 PMID:32033881

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826

G

matrix metallopeptidase 7

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MMP7 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MMP7 mRNA]

NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755

G

matrix metallopeptidase 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP8 mRNA

NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729

G

matrix metallopeptidase 9

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MMP9 mRNA; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 protein]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 mRNA]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 mRNA]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of MMP9 protein]
Dextran Sulfate results in increased expression of MMP9 mRNA; Dextran Sulfate results in increased expression of MMP9 protein

PMID:19285099 PMID:27125760 PMID:29950665 PMID:30972795 PMID:32033881

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

methylmalonyl-CoA mutase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MMUT mRNA

NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342

G

myeloid cell nuclear differentiation antigen

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IFI204 mRNA
Dextran Sulfate results in increased expression of PYHIN1 mRNA

PMID:23894361 PMID:29950665

NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537

G

meiosis-specific nuclear structural 1

increases expression

ISO

Dextran Sulfate results in increased expression of MNS1 mRNA

NCBI chr 8:82,029,587...82,050,276
Ensembl chr 8:82,029,587...82,050,274

G

MOB family member 4, phocein

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MOB4 protein]

NCBI chr 9:64,111,170...64,135,740
Ensembl chr 9:64,111,718...64,135,779

G

MORN repeat containing 2

increases expression

ISO

Dextran Sulfate results in increased expression of MORN2 mRNA

NCBI chr 6:14,718,799...14,725,281

G

macrophage expressed 1

increases expression

ISO

Dextran Sulfate results in increased expression of MPEG1 mRNA

NCBI chr 1:218,876,848...218,881,364
Ensembl chr 1:218,876,069...218,908,715

G

mannose phosphate isomerase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MPI mRNA

NCBI chr 8:66,843,802...66,852,108
Ensembl chr 8:66,844,116...66,852,016

G

megakaryocyte and platelet inhibitory receptor G6b

decreases expression

ISO

Dextran Sulfate results in decreased expression of MPIG6B protein

NCBI chr20:3,761,832...3,765,679
Ensembl chr20:3,762,182...3,765,679

G

myeloperoxidase

multiple interactions
increases secretion
increases activity
increases expression

EXP
ISO

Capsaicin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; lafutidine inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; Oligosaccharides inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Olmesartan Medoxomil inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Rosiglitazone inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; zileuton inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]
Dextran Sulfate results in increased secretion of MPO protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; 4-methylesculetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; 6-formylindolo(3,2-b)carbazole inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; [APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein; [Dextran Sulfate co-treated with Zearalenone] results in increased secretion of MPO protein; [Probenecid binds to Dextrans] inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein]; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased activity of MPO protein; [Streptozocin co-treated with Dextran Sulfate] results in increased activity of MPO protein; Allura Red AC Dye promotes the reaction [Dextran Sulfate results in increased expression of MPO protein]; alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; asperuloside inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; biochanin A inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; CNR2 gene mutant form promotes the reaction [Dextran Sulfate results in increased secretion of MPO protein]; Coumarins inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]]; GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]]; Granisetron inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]]; HU 211 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; icilin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; isovitexin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Leucine inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; ligustilide inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; monotropein inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; morphiceptin analog inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; PNU-282987 inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which affects the activity of MPO protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; SB 203580 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; Tropisetron inhibits the reaction [Dextran Sulfate results in increased expression of MPO protein]; tussilagone inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein]

PMID:11766996 PMID:15339030 PMID:15573930 PMID:16375993 PMID:20637373 More...

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

mercaptopyruvate sulfurtransferase

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MPST protein]

NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650

G

mannose receptor, C type 1

multiple interactions
decreases expression

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 protein; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of MRC1 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in decreased expression of MRC1 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MRC1 protein]
Dextran Sulfate results in decreased expression of MRC1 mRNA; Dextran Sulfate results in decreased expression of MRC1 protein

PMID:25026504 PMID:38164749

NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410

G

mitochondrial ribosomal protein L20

increases expression

ISO

Dextran Sulfate results in increased expression of MRPL20 mRNA

NCBI chr 5:171,690,664...171,695,728
Ensembl chr 5:171,691,198...171,695,728

G

mitochondrial ribosomal protein L22

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of MRPL22 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MRPL22 protein]

NCBI chr10:42,843,165...42,856,243
Ensembl chr10:42,843,222...42,856,227

G

membrane spanning 4-domains A1

increases expression

ISO

Dextran Sulfate results in increased expression of MS4A1 mRNA

NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447

G

methylsterol monooxygenase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of MSMO1 mRNA

NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445

G

moesin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MSN mRNA

NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129

G

methionine sulfoxide reductase B3

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MSRB3 protein]

NCBI chr 7:58,188,827...58,311,459
Ensembl chr 7:57,968,124...58,311,116

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ND1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ND1 protein]

NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ND4 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ND4 protein]

NCBI chr MT:10,160...11,537
Ensembl chr MT:10,145...11,522

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

increases expression

ISO

Dextran Sulfate results in increased expression of ND6 mRNA

NCBI chr MT:13,543...14,061
Ensembl chr MT:13,531...14,049

G

metallothionein 1A

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of MT1 mRNA
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MT1 mRNA

PMID:29950665 PMID:35093514

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 2

increases expression

ISO

Dextran Sulfate results in increased expression of MT2 mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

melatonin receptor 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MTNR1A mRNA

NCBI chr16:53,876,964...53,896,421
Ensembl chr16:53,876,964...53,896,421

G

melatonin receptor 1B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MTNR1B mRNA

NCBI chr 8:20,919,593...20,934,109
Ensembl chr 8:20,919,593...20,934,109

G

mechanistic target of rapamycin kinase

increases expression
increases phosphorylation
multiple interactions
decreases phosphorylation

ISO
EXP

Dextran Sulfate results in increased expression of MTOR protein
Dextran Sulfate results in increased phosphorylation of MTOR protein
celastrol inhibits the reaction [Dextran Sulfate results in increased expression of MTOR protein modified form]
dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]]; Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]
biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MTOR protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]; Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of MTOR protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of MTOR protein]

PMID:26074695 PMID:27611972 PMID:31926917 PMID:32470352 PMID:38648921

NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435

G

myotrophin

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of MTPN protein]

NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924

G

mucin 13, cell surface associated

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MUC13 mRNA

NCBI chr11:80,462,350...80,489,773
Ensembl chr11:80,465,737...80,485,474

G

mucin 2, oligomeric mucus/gel-forming

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of MUC2 mRNA; Dextran Sulfate results in decreased expression of MUC2 protein
biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of MUC2 protein]

PMID:36539404 PMID:37385329 PMID:38648921

NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280

G

mucin 4, cell surface associated

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of MUC4 mRNA

NCBI chr11:81,513,321...81,575,200

G

muscle associated receptor tyrosine kinase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MUSK mRNA

NCBI chr 5:77,853,560...77,967,653
Ensembl chr 5:77,853,736...77,964,338

G

mevalonate diphosphate decarboxylase

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MVD protein]

NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366

G

myosin binding protein C1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYBPC1 mRNA

NCBI chr 7:24,817,770...24,903,681
Ensembl chr 7:24,817,561...24,903,544

G

myosin binding protein C2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYBPC2 mRNA

NCBI chr 1:94,994,121...95,017,584
Ensembl chr 1:104,131,323...104,154,101

G

myosin binding protein C3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYBPC3 mRNA

NCBI chr 3:97,550,974...97,569,216
Ensembl chr 3:97,551,061...97,569,216

G

MYC proto-oncogene, bHLH transcription factor

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MYC mRNA; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MYC protein; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MYC mRNA]; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of MYC protein]

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

MYD88, innate immune signal transduction adaptor

multiple interactions
increases expression

ISO

Dextran Sulfate promotes the reaction [TLR2 protein binds to MYD88 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of MYD88 protein]; flavokawain B inhibits the reaction [Dextran Sulfate promotes the reaction [TLR2 protein binds to MYD88 protein]]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of MYD88 protein]

PMID:35362542 PMID:38583725

NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230

G

myosin heavy chain 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYH8 mRNA

NCBI chr10:52,462,509...52,492,105
Ensembl chr10:52,462,509...52,492,105

G

myosin, heavy chain 9

decreases expression

ISO

Dextran Sulfate results in decreased expression of MYH9 protein

NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963

G

myosin, light chain 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYL1 mRNA

Ensembl chr 9:75,887,227...75,907,971

G

myosin light chain 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYL3 mRNA

NCBI chr 8:119,617,077...119,623,215
Ensembl chr 8:119,616,868...119,623,216

G

myosin, light chain 4

multiple interactions
decreases expression
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of MYL4 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MYL4 protein]

PMID:32272095 PMID:35362542

NCBI chr10:89,949,733...89,985,308
Ensembl chr10:89,949,404...89,985,308

G

myosin light chain 6

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of MYL6 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of MYL6 protein

NCBI chr 7:1,495,301...1,498,512
Ensembl chr 7:1,495,747...1,498,344

G

myosin light chain 7

increases expression

ISO

Dextran Sulfate results in increased expression of MYL7 mRNA

NCBI chr14:84,994,644...84,997,173
Ensembl chr14:84,993,736...84,997,372

G

myosin light chain 9

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of MYL9 protein
Dextran Sulfate results in decreased expression of MYL9 protein

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410

G

myosin light chain kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYLK2 mRNA

NCBI chr 3:161,836,705...161,848,609
Ensembl chr 3:161,836,740...161,848,607

G

myosin Ib

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of MYO1B protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of MYO1B protein]

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328

G

myosin Vb

decreases expression

ISO

Dextran Sulfate results in decreased expression of MYO5B mRNA

NCBI chr18:70,313,717...70,613,918
Ensembl chr18:70,311,990...70,613,918

G

myosin VIIA

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of MYO7A mRNA

NCBI chr 1:161,755,110...161,825,397
Ensembl chr 1:161,755,110...161,825,365

G

marginal zone B and B1 cell-specific protein

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of MZB1 protein]

NCBI chr18:27,513,087...27,515,148
Ensembl chr18:27,513,089...27,515,182

G

Nedd4 binding protein 3

increases expression

ISO

Dextran Sulfate results in increased expression of N4BP3 mRNA

NCBI chr10:36,400,053...36,407,609
Ensembl chr10:36,400,057...36,407,637

G

N-acetylglucosamine kinase

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NAGK protein]

NCBI chr 4:117,838,761...117,846,304
Ensembl chr 4:117,838,826...117,847,836

G

sodium leak channel, non-selective

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of NALCN mRNA

NCBI chr15:106,805,209...107,148,837
Ensembl chr15:106,805,209...107,147,858

G

N-acetylneuraminate synthase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NANS mRNA

NCBI chr 5:65,575,970...65,593,164
Ensembl chr 5:65,576,015...65,610,547

G

N-acyl phosphatidylethanolamine phospholipase D

multiple interactions
decreases expression

ISO

GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in decreased expression of NAPEPLD protein]]; Granisetron inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in decreased expression of NAPEPLD protein]]; Serotonin promotes the reaction [Dextran Sulfate results in decreased expression of NAPEPLD protein]

NCBI chr 4:14,251,591...14,291,010
Ensembl chr 4:14,252,692...14,291,014

G

NSF attachment protein gamma

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of NAPG protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NAPG protein]

NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450

G

N-acetyltransferase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NAT2 mRNA

NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304

G

neurocan

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NCAN mRNA

NCBI chr16:19,335,907...19,362,371
Ensembl chr16:19,335,907...19,362,371

G

neutral cholesterol ester hydrolase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NCEH1 mRNA

NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:112,003,502...112,064,272

G

NCK interacting protein with SH3 domain

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NCKIPSD mRNA

NCBI chr 8:118,390,121...118,401,121
Ensembl chr 8:118,390,159...118,401,118

G

nuclear receptor co-repressor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NCOR2 mRNA

NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612

G

NDRG family member 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of NDRG2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of NDRG2 protein]

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

NADH:ubiquinone oxidoreductase complex assembly factor 3

increases expression

ISO

Dextran Sulfate results in increased expression of NDUFAF3 mRNA

NCBI chr 8:118,139,891...118,141,723
Ensembl chr 8:118,139,892...118,141,723

G

nebulin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NEB mRNA

NCBI chr 3:57,022,822...57,220,752
Ensembl chr 3:57,022,822...57,220,709

G

NEDD4 E3 ubiquitin protein ligase

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of NEDD4 mRNA

NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:82,264,649...82,349,633

G

neuronal differentiation 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NEUROD1 mRNA

NCBI chr 3:84,766,483...84,770,454
Ensembl chr 3:84,764,725...84,770,810

G

nuclear factor of activated T-cells 5

increases activity
decreases expression

ISO

Dextran Sulfate results in increased activity of NFAT5 protein
Dextran Sulfate results in decreased expression of NFAT5 mRNA

PMID:27920257 PMID:35093514

NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418

G

NFE2 like bZIP transcription factor 2

affects response to substance
multiple interactions
decreases expression

ISO

NFE2L2 affects the susceptibility to Dextran Sulfate
[asperuloside co-treated with Dextran Sulfate] results in increased expression of NFE2L2 protein; [Azoxymethane co-treated with Dextran Sulfate] affects the localization of NFE2L2 protein; [Cholecalciferol co-treated with Dextran Sulfate] results in increased expression of NFE2L2 protein; gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of IL6 protein]]; NFE2L2 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the susceptibility to [Azoxymethane co-treated with Dextran Sulfate]; NFE2L2 results in decreased susceptibility to [Dextran Sulfate co-treated with Azoxymethane]; Qingdai compound inhibits the reaction [Dextran Sulfate results in decreased expression of NFE2L2 mRNA]; sinpeinine A inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] affects the localization of NFE2L2 protein]; tussilagone inhibits the reaction [Dextran Sulfate results in decreased expression of NFE2L2 protein]
Dextran Sulfate results in decreased expression of NFE2L2 mRNA; Dextran Sulfate results in decreased expression of NFE2L2 protein

PMID:20404090 PMID:23056183 PMID:23261717 PMID:30142311 PMID:30844440 More...

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor kappa B subunit 1

multiple interactions
affects localization

EXP
ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NFKB1 protein; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NFKB1 protein]
Dextran Sulfate affects the localization of NFKB1 protein
monotropein inhibits the reaction [Dextran Sulfate affects the localization of NFKB1 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKB1 protein]

PMID:19028472 PMID:23261679 PMID:38764152

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

multiple interactions
increases phosphorylation
decreases expression
increases expression

ISO
EXP

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA]; biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; Dextran Sulfate results in increased phosphorylation of and results in increased degradation of NFKBIA protein; Erianin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in decreased expression of NFKBIA protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; monotropein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]

PMID:19940103 PMID:21724996 PMID:23261679 PMID:25472953 PMID:26190278 More...

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

NFKB inhibitor like 1

increases expression

ISO

Dextran Sulfate results in increased expression of NFKBIL1 mRNA

NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,595,284...3,610,294

G

niban apoptosis regulator 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of NIBAN1 mRNA

NCBI chr13:63,674,240...63,827,748
Ensembl chr13:66,224,021...66,377,724

G

nidogen 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NID2 mRNA

NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949

G

nipsnap homolog 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of NIPSNAP1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NIPSNAP1 protein]

NCBI chr14:83,957,714...83,981,579
Ensembl chr14:83,957,702...83,981,576

G

NKD inhibitor of WNT signaling pathway 1

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of NKD1 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of NKD1 mRNA]

NCBI chr19:34,649,803...34,722,846

G

NK2 homeobox 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NKX2-2 mRNA

NCBI chr 3:155,072,621...155,083,699
Ensembl chr 3:155,073,250...155,083,249

G

neuroligin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLGN1 mRNA

NCBI chr 2:110,184,987...111,110,316
Ensembl chr 2:110,186,573...110,909,984

G

neuroligin 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLGN3 mRNA

NCBI chr X:70,469,251...70,497,380
Ensembl chr X:70,469,457...70,497,379

G

neurolysin

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of NLN protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of NLN protein]

NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680

G

NLR family, CARD domain containing 5

increases expression

ISO

Dextran Sulfate results in increased expression of NLRC5 mRNA

NCBI chr19:10,483,601...10,587,223
Ensembl chr19:10,483,755...10,555,786

G

NLR family, pyrin domain containing 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NLRP1A mRNA

NCBI chr10:56,277,134...56,332,229
Ensembl chr10:56,277,134...56,323,880

G

NLR family, pyrin domain containing 3

multiple interactions
increases expression

ISO
EXP

[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of NLRP3 protein; [HU 308 co-treated with Dextran Sulfate] affects the expression of NLRP3 protein; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Dextran Sulfate inhibits the reaction [Zearalenone results in increased expression of NLRP3 mRNA]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 protein]
celastrol inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide promotes the reaction [celastrol inhibits the reaction [Dextran Sulfate results in increased expression of NLRP3 mRNA]]
Dextran Sulfate results in increased expression of NLRP3 mRNA; Dextran Sulfate results in increased expression of NLRP3 protein

PMID:27611972 PMID:30270565 PMID:32470352 PMID:36577154 PMID:37001609

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

neuromedin B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NMB mRNA

NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of NME1 protein
Dextran Sulfate results in increased expression of NME1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NME1 protein]

PMID:35362542 PMID:35999755

NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310

G

NME/NM23 nucleoside diphosphate kinase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of NME2 protein

NCBI chr10:79,394,999...79,400,418
Ensembl chr20:11,179,066...11,179,497
Ensembl chr10:11,179,066...11,179,497

G

neuromedin U receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NMUR2 mRNA

NCBI chr10:40,666,824...40,682,679
Ensembl chr10:40,645,101...40,682,679

G

nitric oxide synthase 2

multiple interactions
increases activity
affects response to substance
increases expression

ISO

3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of NOS2 protein; [Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NOS2 mRNA; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; GW 506033X inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS2 protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased activity of NOS2 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased activity of NOS2 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; monotropein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; RELA protein affects the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; Ursodeoxycholic Acid inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NOS2 mRNA]
NOS2 protein affects the susceptibility to Dextran Sulfate
Dextran Sulfate results in increased expression of NOS2 mRNA; Dextran Sulfate results in increased expression of NOS2 protein

PMID:15459021 PMID:15652231 PMID:16049979 PMID:17438113 PMID:17449036 More...

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

nitric oxide synthase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NOS3 mRNA

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664

G

NOTUM, palmitoleoyl-protein carboxylesterase

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of NOTUM mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of NOTUM mRNA]

NCBI chr10:105,933,245...105,940,327
Ensembl chr10:106,431,572...106,438,654

G

NADPH oxidase 4

increases expression

ISO

Dextran Sulfate results in increased expression of NOX4 mRNA; Dextran Sulfate results in increased expression of NOX4 protein

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483

G

N-acetylneuraminate pyruvate lyase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of NPL protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of NPL protein]

NCBI chr13:68,205,602...68,247,940
Ensembl chr13:68,205,603...68,247,999

G

neuronal pentraxin 1

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of NPTX1 mRNA

NCBI chr10:105,309,578...105,318,829
Ensembl chr10:105,309,578...105,318,863

G

neuropeptide Y

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NPY mRNA

NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310

G

neuropeptide Y receptor Y1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NPY1R mRNA

NCBI chr16:27,804,416...27,814,070
Ensembl chr16:27,804,416...27,813,387

G

neuropeptide Y receptor Y2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NPY2R mRNA

NCBI chr 2:170,200,027...170,210,286
Ensembl chr 2:170,200,027...170,210,448

G

NAD(P)H quinone dehydrogenase 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of NQO1 mRNA; Dextran Sulfate results in decreased expression of NQO1 protein
gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of NQO1 protein]

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NR1H4 mRNA

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NR1I2 mRNA

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

nuclear receptor subfamily 5, group A, member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NR5A2 mRNA

NCBI chr13:50,865,253...50,985,107
Ensembl chr13:50,867,920...50,984,938

G

Nik related kinase

decreases expression

ISO

Dextran Sulfate results in decreased expression of NRK mRNA

NCBI chr X:107,159,154...107,256,417
Ensembl chr X:107,159,233...107,256,417

G

neuropilin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NRP1 mRNA

NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702

G

netrin G1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of NTNG1 mRNA

NCBI chr 2:200,151,979...200,515,031
Ensembl chr 2:200,151,979...200,515,031

G

neurotensin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of NTS mRNA

NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961

G

nucleobindin 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of NUCB1 protein

NCBI chr 1:105,104,793...105,135,730
Ensembl chr 1:105,104,793...105,135,837

G

nuclear distribution C, dynein complex regulator

increases expression

ISO

Dextran Sulfate results in increased expression of NUDC mRNA

NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260

G

nudix hydrolase 16

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of NUDT16 protein]

NCBI chr 8:114,618,706...114,620,761
Ensembl chr 8:114,618,725...114,620,951

G

nucleoporin 133

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NUP133 protein]

NCBI chr19:68,789,065...68,838,692
Ensembl chr19:68,789,065...68,838,692

G

nucleoporin 205

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of NUP205 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of NUP205 protein]

NCBI chr 4:64,822,051...64,887,996
Ensembl chr 4:64,822,065...64,887,988

G

nucleoporin 93

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of NUP93 protein]

NCBI chr19:10,690,154...10,793,937
Ensembl chr19:10,687,115...10,793,380

G

nuclear protein 2, transcriptional regulator

increases expression

ISO

Dextran Sulfate results in increased expression of NUPR2 mRNA

NCBI chr12:32,436,233...32,439,391
Ensembl chr12:32,433,966...32,439,487

G

nucleoredoxin

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of NXN protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of NXN protein]

NCBI chr10:61,607,557...61,745,807
Ensembl chr10:61,607,568...61,745,807

G

occludin

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of OCLN mRNA; Dextran Sulfate results in decreased expression of OCLN protein
7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; [Dietary Fats co-treated with Dextran Sulfate] results in increased expression of OCLN protein; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; daphnetin inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; fucoxanthin inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; HU 211 inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN mRNA]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN mRNA]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein]; obeticholic acid promotes the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in increased expression of OCLN protein]

PMID:23261717 PMID:27995407 PMID:35439472 PMID:35670535 PMID:35894244 More...

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

O-GlcNAcase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of OGA protein
Resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of OGA protein]; thiamet G inhibits the reaction [Dextran Sulfate results in decreased expression of OGA protein]

NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:254,547,311...254,582,855

G

O-linked N-acetylglucosamine (GlcNAc) transferase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of OGT protein
Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of OGT protein]; thiamet G inhibits the reaction [Dextran Sulfate results in increased expression of OGT protein]

NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123

G

olfactory receptor 1088

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR10B1 mRNA

NCBI chr 7:11,761,861...11,765,460
Ensembl chr 7:11,762,338...11,765,415

G

olfactory receptor 1096

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR2Z9 mRNA

NCBI chr 7:15,509,409...15,510,359
Ensembl chr 7:15,509,409...15,510,359

G

olfactory receptor 1877

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR10AD1 mRNA

NCBI chr 7:129,370,144...129,381,836
Ensembl chr 7:131,196,515...131,200,174
Ensembl chr 7:131,196,515...131,200,174

G

olfactory receptor 59

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR51E2 mRNA

NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265

G

opsin 1, medium wave sensitive

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OPN1MW mRNA

NCBI chr X:157,056,355...157,076,716
Ensembl chr X:157,056,355...157,076,716

G

opioid receptor, delta 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OPRD1 mRNA

NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:149,590,244...149,624,999

G

opioid receptor, kappa 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OPRK1 mRNA

NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:18,657,871...18,675,671

G

olfactory receptor family 10 subfamily AL member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR10AL6 mRNA

NCBI chr20:743,522...744,487
Ensembl chr20:743,522...816,076

G

olfactory receptor family 10 subfamily H member 28

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR10H28 mRNA

NCBI chr 7:12,591,719...12,592,669

G

olfactory receptor family 10 subfamily J member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR10J3 mRNA

NCBI chr13:88,199,580...88,200,521
Ensembl chr13:88,199,580...88,200,521

G

olfactory receptor family 11 subfamily A member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR11A4 mRNA

NCBI chr20:1,359,776...1,360,717
Ensembl chr20:1,359,776...1,360,717

G

olfactory receptor family 13 subfamily C member 25

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR13C25 mRNA

NCBI chr 5:72,314,084...72,315,043
Ensembl chr 5:72,314,084...72,315,043

G

olfactory receptor family 1 subfamily B member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR1B1 mRNA

NCBI chr 3:41,030,851...41,031,804
Ensembl chr 3:41,030,851...41,031,804

G

olfactory receptor family 1 subfamily F member 34

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR1F19 mRNA

NCBI chr10:12,830,814...12,839,442

G

olfactory receptor family 1 subfamily M member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR1M1 mRNA

NCBI chr 8:24,723,885...24,734,392
Ensembl chr 8:24,724,284...24,725,225

G

olfactory receptor family 1 subfamily Q member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR1Q1 mRNA

NCBI chr 3:40,897,874...40,898,800
Ensembl chr 3:40,897,874...40,898,800

G

olfactory receptor family 1 subfamily R member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of OR1R1 mRNA

NCBI chr10:59,388,805...59,389,749
Ensembl chr10:59,388,805...59,389,749

G

olfactory receptor family 2 subfamily AG member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR2AG2 mRNA

NCBI chr 1:170,107,441...170,108,391
Ensembl chr 1:170,107,441...170,108,391

G

olfactory receptor family 2 subfamily F member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR2F2 mRNA

NCBI chr 4:72,740,216...72,741,172
Ensembl chr 4:72,740,216...72,741,172

G

olfactory receptor family 2 subfamily L member 13

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR2L13 mRNA

NCBI chr11:94,904,565...94,905,503
Ensembl chr11:94,904,565...94,905,503

G

olfactory receptor family 2 subfamily T member 26

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR2T26 mRNA

NCBI chr10:33,947,662...33,948,615
Ensembl chr10:33,947,662...33,948,615

G

olfactory receptor family 2 subfamily V member 1

increases expression

ISO

Dextran Sulfate results in increased expression of OR2V1 mRNA

NCBI chr10:33,901,067...33,905,416
Ensembl chr10:33,900,397...33,905,496

G

olfactory receptor family 2 subfamily V member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR2V2 mRNA

NCBI chr10:33,880,981...33,881,928
Ensembl chr10:33,880,981...33,881,928

G

olfactory receptor family 3 subfamily A member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR3A4 mRNA

NCBI chr10:59,465,227...59,468,348
Ensembl chr10:59,465,689...59,466,624

G

olfactory receptor family 4 subfamily C member 105

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR4C10B mRNA

NCBI chr 3:95,038,615...95,039,544
Ensembl chr 3:95,038,615...95,039,544

G

olfactory receptor family 4 subfamily C member 123

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR4C123 mRNA

NCBI chr 3:95,728,654...95,729,571
Ensembl chr 3:95,728,654...95,729,571

G

olfactory receptor family 4 subfamily C member 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR4C15 mRNA

NCBI chr 3:95,148,200...95,151,095
Ensembl chr 3:95,148,200...95,149,135

G

olfactory receptor family 4 subfamily E member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR4E2 mRNA

NCBI chr15:27,661,127...27,662,053
Ensembl chr15:27,661,127...27,662,053

G

olfactory receptor family 4 subfamily F member 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR4F15 mRNA

NCBI chr 3:119,011,171...119,020,621
Ensembl chr 3:119,019,683...119,020,645

G

olfactory receptor family 4 subfamily N member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR4N5 mRNA

NCBI chr15:25,647,331...25,648,257
Ensembl chr15:25,647,331...25,648,257

G

olfactory receptor family 4 subfamily Q member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR4Q3 mRNA

NCBI chr15:23,531,029...23,535,992
Ensembl chr15:26,004,612...26,009,053

G

olfactory receptor family 51 subfamily A member 39

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of OR51A39 mRNA

NCBI chr 1:166,564,308...166,565,270
Ensembl chr 1:166,564,308...166,565,270

G

olfactory receptor family 51 subfamily A member 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR51A7 mRNA

NCBI chr 1:166,805,392...166,809,420
Ensembl chr 1:166,807,689...166,808,627

G

olfactory receptor family 51 subfamily B member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR51B6 mRNA

NCBI chr 1:167,759,538...167,760,485
Ensembl chr 1:167,759,538...167,760,485

G

olfactory receptor family 51 subfamily D member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR51D1 mRNA

NCBI chr 1:166,546,510...166,547,567
Ensembl chr 1:166,546,510...166,547,567

G

olfactory receptor family 51 subfamily G member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR51G1 mRNA

NCBI chr 1:166,850,033...166,850,974
Ensembl chr 1:166,850,033...166,850,974

G

olfactory receptor family 51 subfamily G member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR51G2 mRNA

NCBI chr 1:166,833,547...166,834,485
Ensembl chr 1:166,833,547...166,834,485

G

olfactory receptor family 52 subfamily B member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR52B1 mRNA

NCBI chr 1:169,096,272...169,097,216
Ensembl chr 1:169,096,272...169,097,216

G

olfactory receptor family 52 subfamily E member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR52E8 mRNA

NCBI chr 1:168,772,296...168,773,246
Ensembl chr 1:168,772,296...168,773,246

G

olfactory receptor family 5 subfamily B member 12B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR5B12B mRNA

NCBI chr 1:219,467,328...219,468,272
Ensembl chr 1:219,467,328...219,468,272

G

olfactory receptor family 5 subfamily C member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR5C1 mRNA

NCBI chr 3:41,253,167...41,254,150
Ensembl chr 3:41,253,167...41,254,150

G

olfactory receptor family 5 subfamily E member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR5E1 mRNA

NCBI chr 1:162,724,328...162,725,263
Ensembl chr 1:172,159,177...172,160,112

G

olfactory receptor family 5 subfamily H member 17

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR5H19 mRNA

NCBI chr11:41,462,116...41,463,045
Ensembl chr11:54,931,329...54,932,258

G

olfactory receptor family 5 subfamily H member 18

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR5H26 mRNA

NCBI chr11:54,874,390...54,893,013
Ensembl chr11:54,859,228...54,893,444

G

olfactory receptor family 5 subfamily K member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR5K3 mRNA

NCBI chr11:54,728,228...54,729,154
Ensembl chr11:54,728,228...54,729,154

G

olfactory receptor family 5 subfamily P member 76B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR5P76 mRNA

NCBI chr 1:172,023,915...172,024,859
Ensembl chr 1:172,023,915...172,024,859

G

olfactory receptor family 6 subfamily B member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6B3 mRNA

NCBI chr 9:100,495,938...100,496,876
Ensembl chr 9:100,495,938...100,496,876

G

olfactory receptor family 6 subfamily C member 1H

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6C1B mRNA

NCBI chr 7:2,727,844...2,728,794
Ensembl chr 7:2,727,844...2,728,794

G

olfactory receptor family 6 subfamily C member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6C2 mRNA

NCBI chr 7:2,817,089...2,818,027
Ensembl chr 7:2,817,089...2,818,027

G

olfactory receptor family 6 subfamily C member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR6C3 mRNA

NCBI chr 7:5,194,658...5,195,593
Ensembl chr 7:5,194,658...5,195,593

G

olfactory receptor family 6 subfamily C member 68

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of OR6C68 mRNA

NCBI chr 7:5,848,671...5,849,621
Ensembl chr 7:5,848,671...5,849,621

G

olfactory receptor family 6 subfamily C member 74

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6C74 mRNA

NCBI chr 7:7,314,102...7,315,040
Ensembl chr 7:7,314,102...7,315,040

G

olfactory receptor family 6 subfamily C member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6C8 mRNA

NCBI chr 7:2,086,602...2,087,531
Ensembl chr 7:2,086,602...2,087,531

G

olfactory receptor family 6 subfamily K member 14B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR6K4 mRNA

NCBI chr13:88,696,573...88,697,520
Ensembl chr13:88,696,573...88,697,520

G

olfactory receptor family 6 subfamily K member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6K6 mRNA

NCBI chr13:88,680,731...88,681,654
Ensembl chr13:88,680,731...88,681,654

G

olfactory receptor family 6 subfamily N member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR6N2 mRNA

NCBI chr13:88,609,195...88,629,639
Ensembl chr13:88,618,188...88,619,141

G

olfactory receptor, family 7, subfamily E, member 178

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR7E178 mRNA

NCBI chr 8:18,723,515...18,735,910
Ensembl chr 8:26,999,759...27,012,158

G

olfactory receptor family 8 subfamily B member 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of OR8B12 mRNA

NCBI chr 8:45,668,452...45,669,384
Ensembl chr 8:45,668,452...45,669,384

G

olfactory receptor family 8 subfamily G member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR8G2 mRNA

NCBI chr 8:49,163,642...49,166,050

G

olfactory receptor family 9 subfamily A member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of OR9A4 mRNA

NCBI chr 4:70,368,300...70,369,244
Ensembl chr 4:70,368,300...70,369,244

G

olfactory receptor family 9 subfamily G member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OR9G4 mRNA

NCBI chr 3:91,134,643...91,135,581
Ensembl chr 3:91,134,643...91,135,581

G

oncostatin M

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OSM mRNA

NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827

G

oncostatin M receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of OSMR mRNA

NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561

G

ornithine transcarbamylase

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of OTC protein]

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555

G

oxytocin receptor

decreases expression

ISO

Dextran Sulfate results in decreased expression of OXTR mRNA

NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750

G

purinergic receptor P2X 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX5 mRNA

NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935

G

purinergic receptor P2X 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX7 mRNA

NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193

G

pyrimidinergic receptor P2Y4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of P2RY4 mRNA

NCBI chr X:69,722,604...69,757,726
Ensembl chr X:69,721,753...69,753,510

G

pyrimidinergic receptor P2Y6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RY6 mRNA

NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588

G

prolyl 3-hydroxylase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P3H3 mRNA

NCBI chr 4:159,332,514...159,348,428
Ensembl chr 4:159,332,434...159,348,004

G

prolyl 4-hydroxylase subunit beta

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P4HB mRNA
Dextran Sulfate results in decreased expression of P4HB protein

PMID:29950665 PMID:35999755

NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911

G

poly(A) binding protein, nuclear 1

increases expression

ISO

Dextran Sulfate results in increased expression of PABPN1 mRNA

NCBI chr15:32,337,955...32,342,700
Ensembl chr15:32,338,089...32,342,691

G

phosphoprotein membrane anchor with glycosphingolipid microdomains 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PAG1 mRNA

NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:93,964,594...93,977,227

G

p21 (RAC1) activated kinase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PAK4 mRNA

NCBI chr 1:92,977,437...93,016,721
Ensembl chr 1:92,977,437...93,016,721

G

paralemmin

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PALM protein]

NCBI chr 7:10,537,252...10,563,346
Ensembl chr 7:10,537,277...10,563,007

G

pantothenate kinase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PANK1 mRNA

NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824

G

polyamine oxidase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PAOX mRNA

NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481

G

pappalysin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PAPPA mRNA

NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PAPSS2 mRNA

NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616

G

poly (ADP-ribose) polymerase 1

increases cleavage
multiple interactions

ISO

Dextran Sulfate results in increased cleavage of PARP1 protein
[Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein; [Plant Extracts co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased cleavage of PARP1 protein]

PMID:21989142 PMID:25449198

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

poly (ADP-ribose) polymerase family, member 9

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of PARP9 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PARP9 protein]

NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608

G

parvin, beta

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PARVB protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PARVB protein

NCBI chr 7:117,240,238...117,325,744
Ensembl chr 7:117,240,029...117,325,748

G

pro-apoptotic WT1 regulator

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PAWR protein]

NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492

G

paired box 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PAX4 mRNA

NCBI chr 4:58,023,873...58,032,265
Ensembl chr 4:58,023,914...58,028,858

G

paired box 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PAX6 mRNA

NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763

G

propionyl-CoA carboxylase subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PCCB mRNA

NCBI chr 8:110,470,197...110,520,222
Ensembl chr 8:110,469,934...110,520,187

G

protocadherin gamma subfamily B, 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PCDHGB1 mRNA

NCBI chr18:29,501,739...29,508,024

G

phosphoenolpyruvate carboxykinase 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PCK1 protein]

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561

G

proliferating cell nuclear antigen

multiple interactions
decreases expression

ISO
EXP

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PCNA protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PCNA protein; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of PCNA protein]; Ursodeoxycholic Acid inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PCNA protein]
[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PCNA protein; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PCNA protein]

PMID:17438113 PMID:19028472 PMID:34964214 PMID:38648921

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

PEST proteolytic signal containing nuclear protein

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PCNP protein]

NCBI chr11:58,061,885...58,076,436
Ensembl chr11:58,061,570...58,076,436

G

procollagen C-endopeptidase enhancer

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PCOLCE mRNA
Dextran Sulfate results in decreased expression of PCOLCE mRNA

PMID:29950665 PMID:35093514

NCBI chr12:24,720,972...24,727,287
Ensembl chr12:24,720,936...24,727,287

G

Purkinje cell protein 4-like 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PCP4L1 mRNA

NCBI chr13:86,121,463...86,145,097
Ensembl chr13:86,121,464...86,144,899

G

PDGFA associated protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of PDAP1 mRNA

NCBI chr12:14,584,414...14,594,641
Ensembl chr12:14,584,398...14,594,641

G

programmed cell death 4

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PDCD4 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PDCD4 protein]

PMID:32272095 PMID:35362542

NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189

G

phosphodiesterase 10A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDE10A mRNA

NCBI chr 1:54,313,343...54,765,668
Ensembl chr 1:54,317,732...54,764,051

G

phosphodiesterase 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDE1A mRNA

NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212

G

phosphodiesterase 1C

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PDE1C mRNA

NCBI chr 4:86,629,074...87,108,147
Ensembl chr 4:86,626,282...87,193,259

G

phosphodiesterase 2A

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PDE2A mRNA; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PDE2A protein]

PMID:29950665 PMID:32272095

NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466

G

phosphodiesterase 3A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PDE3A mRNA

NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270

G

phosphodiesterase 4A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDE4A mRNA

NCBI chr 8:27,966,978...28,029,721
Ensembl chr 8:27,966,996...28,046,924

G

phosphodiesterase 4B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDE4B mRNA; PDE4B protein affects the reaction [APC protein affects the susceptibility to Dextran Sulfate]

PMID:29950665 PMID:30188895

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267

G

phosphodiesterase 7A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PDE7A mRNA

NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890

G

phosphodiesterase 7B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDE7B mRNA

NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456

G

platelet derived growth factor subunit B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDGFB mRNA

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343

G

platelet derived growth factor receptor alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDGFRA mRNA

NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516

G

platelet derived growth factor receptor beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

protein disulfide isomerase family A, member 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of PDIA3 protein

NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327

G

PDZ and LIM domain 4

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PDLIM4 protein]

NCBI chr10:38,699,444...38,713,696
Ensembl chr10:38,699,444...38,713,659

G

PDS5 cohesin associated factor A

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PDS5A protein]

NCBI chr14:42,905,734...43,004,740
Ensembl chr14:42,905,328...43,004,740

G

prodynorphin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PDYN mRNA

NCBI chr 3:137,354,161...137,366,503
Ensembl chr 3:137,354,161...137,366,503

G

PDZK1 interacting protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of PDZK1IP1 mRNA

NCBI chr 5:128,618,050...128,623,131
Ensembl chr 5:133,841,313...133,859,893

G

proliferation and apoptosis adaptor protein 15

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PEA15A protein]

NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859

G

platelet and endothelial cell adhesion molecule 1

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PECAM1 protein

NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839

G

platelet factor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PF4 mRNA

NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392

G

prefoldin subunit 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PFDN2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PFDN2 protein]

NCBI chr13:86,305,037...86,323,008

G

prefoldin subunit 6

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PFDN6 protein]

NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318

G

profilin 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PFN1 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PFN1 protein

NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611

G

profilin 3

increases expression

ISO

Dextran Sulfate results in increased expression of PFN3 mRNA

NCBI chr17:9,217,595...9,218,122
Ensembl chr17:9,222,719...9,223,249

G

phosphoglycerate mutase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PGAM1 protein

NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203

G

phosphoglycerate mutase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of PGAM2 protein

NCBI chr14:84,895,763...84,897,874
Ensembl chr14:84,895,744...84,897,894

G

placental growth factor

decreases expression
multiple interactions

EXP

Dextran Sulfate results in decreased expression of PGF mRNA
Oligosaccharides inhibits the reaction [Dextran Sulfate results in decreased expression of PGF mRNA]

NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747

G

phosphoglycerate kinase 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PGK1 protein

NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959

G

6-phosphogluconolactonase

decreases expression

ISO

Dextran Sulfate results in decreased expression of PGLS protein

NCBI chr16:18,300,317...18,305,803
Ensembl chr16:18,334,299...18,339,785

G

phosphoglucomutase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PGM1 mRNA

NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159

G

phosphoglucomutase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of PGM2 protein

NCBI chr14:44,519,906...44,553,420
Ensembl chr14:44,519,906...44,553,770

G

phosphoglucomutase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PGM3 mRNA

NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021

G

phosphoglycolate phosphatase

increases expression

ISO

Dextran Sulfate results in increased expression of PGP mRNA

NCBI chr10:13,999,782...14,002,408
Ensembl chr10:13,999,331...14,002,408

G

progesterone receptor membrane component 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PGRMC1 protein]

NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805

G

phosphate regulating endopeptidase X-linked

increases expression

ISO

Dextran Sulfate results in increased expression of PHEX protein

NCBI chr X:41,422,561...41,671,226
Ensembl chr X:41,426,101...41,671,226

G

phosphorylase kinase regulatory subunit alpha 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PHKA1 mRNA

NCBI chr X:71,639,701...71,778,465
Ensembl chr X:71,641,246...71,778,320

G

phosphorylase kinase regulatory subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PHKB mRNA

NCBI chr19:37,179,937...37,383,979
Ensembl chr19:37,186,042...37,383,877

G

phosphoinositide-3-kinase adaptor protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PIK3AP1 mRNA

NCBI chr 1:250,040,250...250,194,364
Ensembl chr 1:250,040,250...250,154,226

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PIK3CA mRNA

NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411

G

phosphoinositide-3-kinase, regulatory subunit 5

increases expression

ISO

Dextran Sulfate results in increased expression of PIK3R5 protein

NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539

G

protein kinase domain containing, cytoplasmic

decreases expression

ISO

Dextran Sulfate results in decreased expression of PKDCC mRNA

NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042

G

pyruvate kinase L/R

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PKLR mRNA

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644

G

plakophilin 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PKP2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PKP2 protein]

NCBI chr11:98,165,974...98,231,916
Ensembl chr11:98,165,974...98,231,916

G

phospholipase A2, group X

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G10 mRNA

NCBI chr10:2,104,927...2,117,998
Ensembl chr10:2,104,927...2,116,172

G

phospholipase A2, group XIIA

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLA2G12A mRNA

NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964

G

phospholipase A2, group XIIB

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G12B mRNA

NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,913,259...27,932,148

G

phospholipase A2 group IIA

increases expression

ISO

Dextran Sulfate results in increased expression of PLA2G2A mRNA

NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297

G

phospholipase A2, group IIC

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLA2G2C mRNA

NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:156,242,451...156,264,676

G

phospholipase A2, group IIE

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLA2G2E mRNA

NCBI chr 5:156,404,639...156,410,421
Ensembl chr 5:156,404,639...156,410,408

G

phospholipase A2, group IIF

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLA2G2F mRNA

NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:156,270,077...156,295,516

G

phospholipase A2 group 4A

increases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of PLA2G4A protein
tussilagone inhibits the reaction [Dextran Sulfate results in increased phosphorylation of PLA2G4A protein]

NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641

G

phospholipase A2 group IVC

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PLA2G4C protein
Dextran Sulfate results in increased expression of PLA2G4C protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PLA2G4C protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PLA2G4C protein]

PMID:32272095 PMID:35362542

NCBI chr 1:83,315,017...83,411,342
Ensembl chr 1:83,382,068...83,410,037

G

phospholipase A2, group IVF

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLA2G4F mRNA

NCBI chr 3:127,702,603...127,720,429
Ensembl chr 3:127,703,841...127,718,348

G

plasminogen activator, tissue type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLAT mRNA

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696

G

plasminogen activator, urokinase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLAU mRNA

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030

G

plasminogen activator, urokinase receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLAUR mRNA

NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130

G

phospholipase C, beta 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLCB2 mRNA

NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221

G

phospholipase C, beta 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLCB4 mRNA

NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113

G

phospholipase C, epsilon 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PLCE1 mRNA

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828

G

phospholipase C, gamma 2

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PLCG2 protein]

NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684

G

phospholipase D family, member 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of PLD3 mRNA

NCBI chr 1:91,949,465...91,971,834
Ensembl chr 1:91,949,467...91,961,207

G

pleckstrin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLEK mRNA

NCBI chr14:95,598,650...95,631,326
Ensembl chr14:95,598,654...95,655,721

G

pleckstrin homology domain containing O2

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PLEKHO2 protein]

NCBI chr 8:74,973,578...75,000,532
Ensembl chr 8:74,974,740...75,000,430

G

plasminogen

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLG mRNA

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PLOD2 mRNA

NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022

G

plastin 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PLS1 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PLS1 protein

NCBI chr 8:105,196,312...105,306,252
Ensembl chr 8:105,197,455...105,292,447

G

phospholipid transfer protein

decreases expression

ISO

Dextran Sulfate results in decreased expression of PLTP mRNA

NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:173,994,162...174,012,505

G

plexin A1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PLXNA1 mRNA

NCBI chr 4:123,295,165...123,340,132
Ensembl chr 4:123,297,244...123,340,428

G

plexin C1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PLXNC1 mRNA

NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:31,276,978...31,431,092

G

plexin D1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PLXND1 mRNA

NCBI chr 4:150,675,377...150,715,706
Ensembl chr 4:150,675,377...150,715,566

G

premelanosome protein

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PMEL protein

NCBI chr 7:1,721,948...1,733,248
Ensembl chr 7:1,722,297...1,733,248

G

phosphomannomutase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PMM2 mRNA

NCBI chr10:7,468,371...7,489,574
Ensembl chr10:7,468,372...7,489,554

G

pancreatic lipase-related protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PNLIPRP1 mRNA

NCBI chr 1:267,854,027...267,869,654
Ensembl chr 1:267,854,027...267,869,654

G

purine nucleoside phosphorylase

decreases expression

ISO

Dextran Sulfate results in decreased expression of PNP2 mRNA

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162

G

polyribonucleotide nucleotidyltransferase 1

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PNPT1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PNPT1 protein]

PMID:32272095 PMID:35362542

NCBI chr14:107,078,486...107,109,628
Ensembl chr14:107,078,469...107,109,628

G

podocalyxin-like

decreases expression

ISO

Dextran Sulfate results in decreased expression of PODXL mRNA

NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789

G

RNA polymerase II, I and III subunit H

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of POLR2H protein]

NCBI chr11:93,696,423...93,701,902
Ensembl chr10:105,353,444...105,354,241
Ensembl chr11:105,353,444...105,354,241

G

paraoxonase 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of PON3 mRNA

NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244

G

periostin

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of POSTN protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of POSTN protein]

NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300

G

peroxisome proliferator activated receptor alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

peroxisome proliferator-activated receptor delta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PPARD mRNA

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707

G

peroxisome proliferator-activated receptor gamma

increases expression
decreases localization
affects localization
multiple interactions

ISO

Dextran Sulfate results in increased expression of PPARG protein
Dextran Sulfate results in decreased localization of PPARG protein
Dextran Sulfate affects the localization of PPARG protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PPARG mRNA; formononetin inhibits the reaction [Dextran Sulfate results in decreased localization of PPARG protein]; ligustilide inhibits the reaction [Dextran Sulfate affects the localization of PPARG protein]; Mesalamine inhibits the reaction [Dextran Sulfate affects the localization of PPARG protein]

PMID:23261717 PMID:29950665 PMID:33130971 PMID:39855309

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

multiple interactions
decreases expression

EXP

Hesperidin inhibits the reaction [Dextran Sulfate results in decreased expression of PPARGC1A protein]

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

peptidylprolyl isomerase A

decreases expression

ISO

Dextran Sulfate results in decreased expression of PPIA protein

NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115

G

peptidylprolyl isomerase C

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PPIC protein]

NCBI chr18:49,040,690...49,053,296
Ensembl chr18:49,040,692...49,053,466

G

peptidylprolyl isomerase H

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of PPIH protein
Dextran Sulfate results in increased expression of PPIH protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PPIH protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PPIH protein]

PMID:32272095 PMID:35362542

NCBI chr 5:138,191,624...138,209,625
Ensembl chr 5:138,191,624...138,209,580

G

protein phosphatase 1 catalytic subunit gamma

increases expression

ISO

Dextran Sulfate results in increased expression of PPP1CC mRNA

NCBI chr12:40,043,822...40,061,301
Ensembl chr12:40,043,822...40,061,341

G

protein phosphatase 1, regulatory (inhibitor) subunit 14A

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of PPP1R14A protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of PPP1R14A protein]

NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147

G

protein phosphatase 1, regulatory (inhibitor) subunit 1B

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PPP1R1B protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PPP1R1B protein]

PMID:32272095 PMID:35362542

NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,844,036...83,853,063

G

protein phosphatase 2, regulatory subunit B', delta

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of PPP2R5D protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PPP2R5D protein]

NCBI chr 9:21,767,963...21,797,997
Ensembl chr 9:21,767,688...21,797,996

G

protein phosphatase 3 catalytic subunit gamma

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PPP3CC mRNA

NCBI chr15:51,699,586...51,771,763
Ensembl chr15:51,700,255...51,771,538

G

pancreatic polypeptide

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PPY mRNA

NCBI chr10:87,554,941...87,556,236
Ensembl chr10:87,554,950...87,556,719

G

peroxiredoxin 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of PRDX1 protein

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

protein kinase AMP-activated catalytic subunit alpha 1

decreases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in decreased phosphorylation of PRKAA1 protein
biochanin A inhibits the reaction [Dextran Sulfate results in decreased phosphorylation of PRKAA1 protein]

NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450

G

protein kinase AMP-activated catalytic subunit alpha 2

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PRKAA2 protein]

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324

G

protein kinase cAMP-activated catalytic subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRKACB mRNA

NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315

G

protein kinase AMP-activated non-catalytic subunit gamma 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PRKAG2 mRNA

NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939

G

protein kinase C, alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PRKCA mRNA

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572

G

protein kinase C, beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740

G

protein kinase C, theta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRKCQ mRNA

NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508

G

protein kinase cGMP-dependent 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of PRKG1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PRKG1 protein]

NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005

G

protein kinase cGMP-dependent 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PRKG2 mRNA

NCBI chr14:10,864,020...10,972,617
Ensembl chr14:10,864,186...10,972,614

G

prolactin family 3, subfamily D member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRL3D1 mRNA

NCBI chr17:38,184,825...38,190,787

G

prolactin receptor

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PRLR mRNA
Dextran Sulfate results in decreased expression of PRLR mRNA

PMID:29950665 PMID:35093514

NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882

G

protamine 3

increases expression

ISO

Dextran Sulfate results in increased expression of PRM3 mRNA

NCBI chr10:4,877,471...4,877,985

G

protein C, inactivator of coagulation factors Va and VIIIa

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PROC mRNA

NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964

G

prolyl-tRNA synthetase associated domain containing 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of PRORSD1 protein]

NCBI chr14:107,458,910...107,461,179
Ensembl chr14:107,458,857...107,461,205

G

protein S

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PROS1 mRNA

NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852

G

prospero homeobox 1

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of PROX1 mRNA

NCBI chr13:104,196,615...104,251,007
Ensembl chr13:104,200,378...104,250,975

G

pre-mRNA processing factor 38B

increases expression

ISO

Dextran Sulfate results in increased expression of PRPF38B mRNA

NCBI chr 2:199,241,312...199,250,342
Ensembl chr 2:199,241,313...199,250,338

G

pre-mRNA splicing tri-snRNP complex factor PRPF4

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of PRPF4 protein]

NCBI chr 5:80,875,511...80,889,501
Ensembl chr 5:80,875,498...80,889,497

G

proline-rich coiled-coil 1

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of PRRC1 protein]

NCBI chr18:53,010,606...53,047,601
Ensembl chr18:53,010,600...53,045,015

G

proline-rich coiled-coil 2C

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of PRRC2C mRNA

NCBI chr13:77,537,226...77,606,926
Ensembl chr13:77,537,814...77,607,001

G

serine protease 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRSS3 mRNA; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRY4 mRNA

NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223

G

peroxiredoxin like 2B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PRXL2B mRNA

NCBI chr 5:170,744,953...170,747,556
Ensembl chr 5:170,744,953...170,747,556

G

presenilin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PSEN1 mRNA

NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:109,060,352...109,106,189

G

proteasome 20S subunit beta 8

increases expression

ISO

Dextran Sulfate results in increased expression of PSMB8 mRNA

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031

G

proline-serine-threonine phosphatase-interacting protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PSTPIP1 mRNA

NCBI chr 8:65,395,328...65,434,616
Ensembl chr 8:65,395,358...65,434,627

G

platelet-activating factor receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTAFR mRNA

NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408

G

phosphatase and tensin homolog

multiple interactions

ISO

[APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form; resorcinol inhibits the reaction [[APC protein affects the susceptibility to Dextran Sulfate] which results in increased chemical synthesis of PTEN protein modified form]

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330

G

prostaglandin D2 receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGDR2 mRNA

NCBI chr 1:217,010,183...217,015,044
Ensembl chr 1:216,995,629...217,022,393

G

prostaglandin D2 synthase

multiple interactions
increases expression
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGDS mRNA; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased expression of PTGDS protein]
Dextran Sulfate results in decreased expression of PTGDS protein

PMID:29950665 PMID:30489199 PMID:35999755

NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978

G

prostaglandin E receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGER2 mRNA

NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950

G

prostaglandin E receptor 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGER3 mRNA

NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846

G

prostaglandin E receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGER4 mRNA

NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135

G

prostaglandin E synthase

multiple interactions
increases expression

EXP
ISO

resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]
7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGES mRNA; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGES protein]

PMID:19228061 PMID:20132809 PMID:29950665 PMID:30489199 PMID:36543318

NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995

G

prostaglandin E synthase 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of PTGES3 protein

NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695

G

prostaglandin F receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGFR mRNA

NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:243,393,350...243,425,623

G

prostaglandin I2 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGIR mRNA

NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:86,707,503...86,711,874

G

prostaglandin I2 synthase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGIS mRNA

NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650

G

prostaglandin reductase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGR1 mRNA

NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811

G

prostaglandin-endoperoxide synthase 2

multiple interactions
increases expression

ISO
EXP

[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTGS2 mRNA; AHR gene mutant form promotes the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; DUSP1 protein affects the reaction [Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein]; monotropein inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; NFE2L2 protein affects the reaction [Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]
Dextran Sulfate results in increased expression of PTGS2 mRNA; Dextran Sulfate results in increased expression of PTGS2 protein
resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]

PMID:15459021 PMID:15652231 PMID:16049979 PMID:17438113 PMID:19228061 More...

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

parathyroid hormone 1 receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTH1R mRNA

NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108

G

parathyroid hormone-like hormone

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PTHLH mRNA

NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454

G

pleiotrophin

decreases expression

ISO

Dextran Sulfate results in decreased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

protein tyrosine phosphatase, receptor type, C

increases expression

ISO

Dextran Sulfate results in increased expression of PTPRC mRNA

NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746

G

protein tyrosine phosphatase, receptor type, H

decreases expression

ISO

Dextran Sulfate results in decreased expression of PTPRH mRNA

NCBI chr 1:78,272,414...78,318,977
Ensembl chr 1:78,271,276...78,318,977

G

protein tyrosine phosphatase, receptor type, M

decreases expression

ISO

Dextran Sulfate results in decreased expression of PTPRM protein

NCBI chr 9:114,086,380...114,791,000
Ensembl chr 9:114,086,380...114,790,477

G

protein tyrosine phosphatase, receptor type, U

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTPRU mRNA

NCBI chr 5:149,234,624...149,308,857
Ensembl chr 5:149,234,624...149,308,833

G

PYD and CARD domain containing

multiple interactions
increases expression

ISO

[Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD mRNA; [Dextran Sulfate co-treated with Zearalenone] results in increased expression of PYCARD protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD mRNA]; Zearalenone inhibits the reaction [Dextran Sulfate results in increased expression of PYCARD protein]
Dextran Sulfate results in increased expression of PYCARD mRNA; Dextran Sulfate results in increased expression of PYCARD protein

PMID:30270565 PMID:34964214

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

glycogen phosphorylase B

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of PYGB protein
Dextran Sulfate results in decreased expression of PYGB protein

NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961

G

glycogen phosphorylase L

decreases expression

ISO

Dextran Sulfate results in decreased expression of PYGL protein

NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269

G

peptide YY

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of PYY mRNA

NCBI chr10:87,561,347...87,562,470
Ensembl chr10:87,561,353...87,562,206

G

R3H domain and coiled-coil containing 1

increases expression

ISO

Dextran Sulfate results in increased expression of R3HCC1 mRNA

NCBI chr15:44,774,552...44,781,864
Ensembl chr15:51,184,328...51,201,576

G

RAB11B, member RAS oncogene family

decreases expression

ISO

Dextran Sulfate results in decreased expression of RAB11B protein

NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:15,223,534...15,236,756

G

RAB1B, member RAS oncogene family

multiple interactions
increases expression
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RAB1B protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of RAB1B protein]

PMID:32272095 PMID:35362542

NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337
Ensembl chr X:211,835,073...211,843,337

G

RAB21, member RAS oncogene family

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of RAB21 protein

NCBI chr 7:52,790,158...52,814,943
Ensembl chr 7:52,790,165...52,814,943

G

RAB27A, member RAS oncogene family

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RAB27A protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RAB27A protein]

NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262

G

RAB27B, member RAS oncogene family

multiple interactions
decreases expression

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of RAB27B protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of RAB27B mRNA
Dextran Sulfate results in decreased expression of RAB27B protein

PMID:29950665 PMID:35999755

NCBI chr18:65,870,230...66,069,597
Ensembl chr18:65,876,342...66,067,700

G

RAB32, member RAS oncogene family

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RAB32 protein]

NCBI chr 1:6,766,448...6,781,258
Ensembl chr 1:6,766,455...6,781,258

G

RAB4B, member RAS oncogene family

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RAB4B protein]

NCBI chr 1:91,589,047...91,600,426
Ensembl chr 1:91,589,047...91,600,337

G

Rac family small GTPase 3

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of RAC3 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of RAC3 mRNA]

NCBI chr10:106,501,133...106,503,569
Ensembl chr10:106,501,135...106,503,569

G

receptor activity modifying protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RAMP1 mRNA

NCBI chr 9:99,213,031...99,263,696

G

receptor activity modifying protein 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RAMP2 mRNA

NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,688,703...86,691,231

G

receptor activity modifying protein 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RAMP3 mRNA

NCBI chr14:85,741,314...85,758,813
Ensembl chr14:85,755,211...85,758,818

G

RAN binding protein 3

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of RANBP3 protein]

NCBI chr 9:1,594,344...1,631,587
Ensembl chr 9:1,594,346...1,631,587

G

RAP1B, member of RAS oncogene family

decreases expression

ISO

Dextran Sulfate results in decreased expression of RAP1B protein

NCBI chr 7:55,308,922...55,342,217
Ensembl chr 7:55,308,922...55,342,217

G

Rap guanine nucleotide exchange factor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RAPGEF4 mRNA

NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:77,217,039...77,509,978

G

retinoic acid receptor, gamma

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RARG mRNA

NCBI chr 7:135,246,427...135,268,889
Ensembl chr 7:135,246,427...135,268,889

G

retinoic acid receptor responder 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of RARRES1 mRNA

NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024

G

RAS guanyl releasing protein 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RASGRP3 mRNA

NCBI chr 6:25,647,386...25,745,952
Ensembl chr 6:25,647,386...25,710,591

G

Ras association domain family member 1

increases response to substance
multiple interactions

ISO

RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate
[RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in decreased activity of STK4 protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased activity of MPO protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased expression of BAX mRNA; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased expression of BAX protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased phosphorylation of and affects the localization of YAP1 protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased secretion of CCL2 protein; [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased secretion of IL6 protein

NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805

G

RNA binding motif protein 47

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of RBM47 protein]

NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,466,335...42,543,163

G

retinol binding protein 4

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of RBP4 protein

NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898

G

RNA binding protein, mRNA processing factor

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RBPMS protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RBPMS protein]

NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503

G

RCC1 and BTB domain containing protein 2

increases expression

ISO

Dextran Sulfate results in increased expression of RCBTB2 mRNA

NCBI chr15:54,729,367...54,774,004
Ensembl chr15:54,729,332...54,793,313

G

reticulocalbin 3

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RCN3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RCN3 protein]

NCBI chr 1:104,700,969...104,710,228
Ensembl chr 1:104,700,545...104,710,249

G

radixin

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RDX protein]

NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967

G

regenerating family member 1 alpha

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in increased expression of REG1 protein

NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585

G

regenerating family member 3 beta

increases expression

ISO

Dextran Sulfate results in increased expression of REG3B mRNA

NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014

G

regenerating family member 3 gamma

increases expression

ISO

Dextran Sulfate results in increased expression of REG3G mRNA

NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases localization
increases expression
increases phosphorylation
affects localization
increases activity

ISO
EXP

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; [Azoxymethane co-treated with Dextran Sulfate] affects the localization of and results in increased phosphorylation of RELA protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of RELA protein; [Streptozocin co-treated with Dextran Sulfate] results in increased phosphorylation of RELA protein; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein]; asperuloside inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] affects the localization of and results in increased phosphorylation of RELA protein]; biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Camptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] affects the localization of and results in increased phosphorylation of RELA protein]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Dextran Sulfate results in decreased expression of and results in increased phosphorylation of RELA protein; Dextran Sulfate results in increased activity of and results in increased phosphorylation of RELA protein; Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein; Dextran Sulfate results in increased expression of and affects the localization of RELA protein; Dextran Sulfate results in increased phosphorylation of and affects the localization of RELA protein; EIF2AK2 protein affects the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of and results in increased phosphorylation of RELA protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased localization of RELA protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of and results in increased activity of RELA protein]; GW 506033X inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of and affects the localization of RELA protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; monotropein inhibits the reaction [Dextran Sulfate affects the localization of RELA protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein modified form]; nuciferine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; Plant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] affects the localization of and results in increased phosphorylation of RELA protein]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased activity of and results in increased phosphorylation of RELA protein]; RELA protein affects the reaction [Dextran Sulfate results in increased expression of NOS2 mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of RELA protein]
banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of RELA protein]; Dextran Sulfate results in increased expression of and results in increased phosphorylation of RELA protein; palmatine inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of RELA protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of RELA protein]
Dextran Sulfate results in increased expression of RELA protein; Dextran Sulfate results in increased expression of RELA protein modified form

PMID:21724996 PMID:23261679 PMID:24038091 PMID:25449198 PMID:25472953 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

renin binding protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RENBP mRNA

NCBI chr X:156,812,785...156,821,860
Ensembl chr X:156,812,411...156,821,838

G

retention in endoplasmic reticulum sorting receptor 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of RER1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of RER1 protein]

NCBI chr 5:170,916,643...170,929,073
Ensembl chr 5:170,916,905...170,928,980

G

resistin like beta

increases expression

ISO

Dextran Sulfate results in increased expression of RETNLB mRNA

NCBI chr11:65,446,433...65,448,319
Ensembl chr11:65,446,434...65,448,319

G

retinol saturase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of RETSAT mRNA

NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552

G

RNA exonuclease 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of REXO2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of REXO2 protein]

NCBI chr 8:57,708,420...57,720,142
Ensembl chr 8:57,707,558...57,720,142

G

retinal G protein coupled receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RGR mRNA

NCBI chr16:12,821,858...12,836,665
Ensembl chr16:12,821,858...12,836,486

G

regulator of G-protein signaling 10

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RGS10 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RGS10 protein]

NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904

G

regulator of G-protein signaling 19

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RGS19 mRNA

NCBI chr 3:189,182,041...189,190,494
Ensembl chr 3:189,182,383...189,190,736

G

regulator of G-protein signaling 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RGS7 mRNA

NCBI chr13:89,511,492...89,941,082
Ensembl chr13:89,511,150...89,940,987

G

Rh family B glycoprotein

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of RHBG mRNA
Dextran Sulfate results in decreased expression of RHBG mRNA

PMID:29950665 PMID:35093514

NCBI chr 2:176,002,886...176,015,201
Ensembl chr 2:176,002,887...176,015,609

G

ras homolog family member J

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RHOJ mRNA

NCBI chr 6:99,771,104...99,853,366
Ensembl chr 6:99,771,252...99,853,999

G

reactive intermediate imine deaminase A homolog

decreases expression

ISO

Dextran Sulfate results in decreased expression of RIDA protein

NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692

G

receptor interacting serine/threonine kinase 1

multiple interactions
increases expression

ISO

dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of RIPK1 protein]

NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167

G

receptor-interacting serine-threonine kinase 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of RIPK3 protein
dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of RIPK3 protein]

NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025

G

ribonuclease L

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RNASEL protein]

NCBI chr13:68,446,641...68,460,804
Ensembl chr13:68,446,882...68,459,557

G

ring finger protein 213

decreases expression

ISO

Dextran Sulfate results in decreased expression of RNF213 mRNA

NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148

G

RAR-related orphan receptor C

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of RORC mRNA; Dextran Sulfate results in increased expression of RORC mRNA alternative form
Chlorpyrifos inhibits the reaction [Dextran Sulfate results in increased expression of RORC mRNA alternative form]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of RORC mRNA]

PMID:31737179 PMID:31807802

NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566

G

ribosomal protein L39 like 1

increases expression

ISO

Dextran Sulfate results in increased expression of RPL39L mRNA

NCBI chr10:5,962,506...5,966,621
Ensembl chr10:5,962,515...5,966,621

G

ribosomal protein L41

increases expression

ISO

Dextran Sulfate results in increased expression of RPL41 mRNA

NCBI chr 7:1,562,417...1,563,497

G

ribosomal protein S14

increases expression

ISO

Dextran Sulfate results in increased expression of RPS14 mRNA

NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091

G

ribosomal protein S15

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RPS15 protein
Dextran Sulfate results in increased expression of RPS15 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RPS15 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of RPS15 protein]

PMID:32272095 PMID:35362542

NCBI chr 7:10,066,572...10,068,167
Ensembl chr 7:10,066,677...10,068,123

G

ribosomal protein S15a

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RPS15A protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RPS15A protein]

NCBI chr 1:181,854,396...181,861,330
Ensembl chr 1:181,854,396...181,861,201

G

ribosomal protein S21, pseudogene 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of RPS21 protein]

NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490

G

ribosomal protein S29

increases expression

ISO

Dextran Sulfate results in increased expression of RPS29 mRNA

NCBI chr 6:93,371,293...93,372,731
Ensembl chr13:87,816,954...87,817,267
Ensembl chr 6:87,816,954...87,817,267

G

ribosomal protein S6

multiple interactions
increases phosphorylation

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]]; [Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of RPS6 protein; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6 protein]

PMID:19931517 PMID:31676321

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566

G

ribosomal protein S6 kinase B1

increases phosphorylation
decreases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein
Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein
dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]]; Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RPS6KB1 protein]; CNR2 protein affects the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]; Nicotine promotes the reaction [Dextran Sulfate results in decreased phosphorylation of RPS6KB1 protein]

PMID:27611972 PMID:31676321 PMID:31926917

NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238

G

RAS related 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of RRAS2 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of RRAS2 protein]

NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551

G

ribosome binding protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of RRBP1 mRNA

NCBI chr 3:151,768,386...151,830,255
Ensembl chr 3:151,768,386...151,830,255

G

ribosomal RNA processing 1

increases expression

ISO

Dextran Sulfate results in increased expression of RRP1 mRNA

NCBI chr20:10,260,580...10,271,829
Ensembl chr20:10,260,592...10,275,076

G

radial spoke head component 1

increases expression

ISO

Dextran Sulfate results in increased expression of RSPH1 mRNA

NCBI chr20:9,343,258...9,361,988
Ensembl chr20:9,343,261...9,361,988

G

Ras suppressor protein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of RSU1 protein

NCBI chr17:81,037,848...81,286,127
Ensembl chr17:81,042,595...81,286,030

G

RT1 class II, locus Ba

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of H2-AA mRNA
Dextran Sulfate results in decreased expression of H2-AA protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of H2-AA protein]

PMID:23894361 PMID:35362542

NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653

G

RT1 class II, locus Bb

increases expression

ISO

Dextran Sulfate results in increased expression of H2-AB1 mRNA

NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118

G

RT1 class II, locus Db1

increases expression

ISO

Dextran Sulfate results in increased expression of H2-EB1 mRNA

NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165

G

RT1 class II, locus DMa

increases expression

ISO

Dextran Sulfate results in increased expression of H2-DMA mRNA

NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335

G

RT1 class II, locus DOb

increases expression

ISO

Dextran Sulfate results in increased expression of H2-OB mRNA

NCBI chr20:4,621,336...4,627,537
Ensembl chr20:4,619,694...4,627,523

G

RT1 class Ib, locus M3, gene 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of H2-M3 mRNA

NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366

G

relaxin family peptide receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RXFP1 mRNA

NCBI chr 2:167,070,414...167,191,616
Ensembl chr 2:167,070,417...167,191,556

G

relaxin family peptide/INSL5 receptor 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RXFP4 mRNA

NCBI chr 2:174,123,510...174,124,664

G

retinoid X receptor alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of RXRA mRNA

NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417

G

ryanodine receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RYR1 mRNA

NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305

G

S100 calcium binding protein A11

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of S100A11 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of S100A11 protein]

NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541

G

S100 calcium-binding protein A4

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of S100A4 protein
Dextran Sulfate results in decreased expression of S100A4 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of S100A4 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of S100A4 protein]

PMID:32272095 PMID:35362542

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837

G

S100 calcium binding protein A8

increases expression

ISO

Dextran Sulfate results in increased expression of S100A8 mRNA

NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221

G

S100 calcium binding protein A9

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of S100A9 protein
Dextran Sulfate results in decreased expression of S100A9 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of S100A9 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of S100A9 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of S100A9 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of S100A9 protein]

PMID:32272095 PMID:35362542

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870

G

S100 calcium binding protein G

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of S100G mRNA

NCBI chr X:35,337,636...35,340,205
Ensembl chr X:35,337,675...35,340,205

G

sphingosine-1-phosphate receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of S1PR2 mRNA

NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:27,774,566...27,790,577

G

scaffold attachment factor B

increases expression

ISO

Dextran Sulfate results in increased expression of SAFB mRNA

NCBI chr 9:1,504,657...1,525,545
Ensembl chr 9:1,504,456...1,525,781

G

scaffold attachment factor B2

increases expression

ISO

Dextran Sulfate results in increased expression of SAFB2 mRNA

NCBI chr 9:1,482,985...1,504,142
Ensembl chr 9:1,479,061...1,504,142

G

Sin3A associated protein 30

increases expression

ISO

Dextran Sulfate results in increased expression of SAP30 mRNA

NCBI chr16:37,758,494...37,763,825
Ensembl chr16:37,757,656...37,763,823

G

sarcosine dehydrogenase

decreases expression

ISO

Dextran Sulfate results in decreased expression of SARDH mRNA

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137

G

SAP domain containing ribonucleoprotein

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SARNP protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SARNP protein]

NCBI chr 7:1,835,597...1,889,833
Ensembl chr 7:1,835,597...1,897,295

G

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

increases expression

ISO

Dextran Sulfate results in increased expression of SART1 mRNA

NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486

G

sterol-C5-desaturase

decreases expression

ISO

Dextran Sulfate results in decreased expression of SC5D mRNA

NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277

G

secretory carrier membrane protein 1

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SCAMP1 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SCAMP1 protein]

NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742

G

stearoyl-CoA desaturase

decreases expression

ISO

Dextran Sulfate results in decreased expression of SCD1 mRNA

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

stearoyl-Coenzyme A desaturase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of SCD2 mRNA

NCBI chr 1:253,118,377...253,131,436
Ensembl chr 1:253,117,655...253,128,874

G

secretoglobin family 1A member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SCGB1A1 mRNA

NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686

G

secretoglobin, family 3A, member 1

increases expression

ISO

Dextran Sulfate results in increased expression of SCGB3A1 mRNA

NCBI chr10:34,469,166...34,470,473
Ensembl chr10:34,468,002...34,470,583

G

scinderin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SCIN mRNA

NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:62,836,641...62,915,287

G

sodium channel epithelial 1 subunit alpha

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SCNN1A mRNA

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405

G

sodium channel epithelial 1 subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SCNN1B mRNA

NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049

G

secretin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SCT mRNA

NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:205,812,435...205,813,246

G

syndecan 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SDC3 mRNA

NCBI chr 5:148,249,792...148,282,524
Ensembl chr 5:148,271,842...148,280,614

G

SEC62 homolog, preprotein translocation factor

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SEC62 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SEC62 protein]

NCBI chr 2:114,499,317...114,526,705
Ensembl chr 2:114,499,317...114,530,321

G

selectin P

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SELP mRNA

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987

G

serpin family A member 3N

increases expression

ISO

Dextran Sulfate results in increased expression of SERPINA3N mRNA

PMID:23894361 PMID:35093514

NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415

G

serpin family A member 5

multiple interactions

ISO

Dextran Sulfate affects the reaction [SEMG2 protein binds to SERPINA5 protein]

NCBI chr 6:128,774,006...128,793,187
Ensembl chr 6:128,784,991...128,793,186

G

serpin family B member 1A

decreases expression

ISO

Dextran Sulfate results in decreased expression of SERPINB1A protein

NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,799,415...31,808,166

G

serpin family E member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

serpin family G member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SERPING1 mRNA

NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717

G

splicing factor 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SF1 protein]

NCBI chr 1:213,090,256...213,112,688
Ensembl chr 1:213,099,260...213,113,590

G

splicing factor 3A subunit 2

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SF3A2 protein]

NCBI chr 7:9,560,182...9,566,205
Ensembl chr 7:9,560,182...9,566,205

G

sarcoglycan, delta

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SGCD protein]

NCBI chr10:31,847,713...32,829,554
Ensembl chr10:31,781,748...32,419,064

G

serum/glucocorticoid regulated kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SGK2 mRNA

NCBI chr 3:172,063,625...172,089,000
Ensembl chr 3:172,063,776...172,089,011

G

sphingomyelin synthase 2

increases expression

ISO

Dextran Sulfate results in increased expression of SGMS2 mRNA

NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:222,567,664...222,590,807

G

sphingosine-1-phosphate phosphatase 2

increases expression
multiple interactions

EXP

Dextran Sulfate results in increased expression of SGPP2 mRNA
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of SGPP2 mRNA]

NCBI chr 9:87,211,155...87,331,787
Ensembl chr 9:87,211,717...87,333,132

G

SH3 domain binding glutamate rich protein like

decreases expression

ISO

Dextran Sulfate results in decreased expression of SH3BGRL protein

NCBI chr X:78,242,704...78,343,633
Ensembl chr X:78,242,405...78,343,634

G

SH3 domain binding glutamate-rich protein like 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of SH3BGRL3 protein

NCBI chr 5:151,637,897...151,639,270
Ensembl chr 5:151,637,674...151,639,395

G

SH3 domain containing GRB2 like 2, endophilin A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SH3GL2 mRNA

NCBI chr 5:104,699,270...104,874,724
Ensembl chr 5:104,698,929...105,159,896

G

SH3 domain-containing kinase-binding protein 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SH3KBP1 mRNA

NCBI chr X:38,686,530...39,031,658
Ensembl chr X:38,686,530...39,031,393

G

serine hydroxymethyltransferase 1

decreases expression
increases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SHMT1 protein
Dextran Sulfate results in increased expression of SHMT1 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SHMT1 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SHMT1 protein]

PMID:32272095 PMID:35362542

NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,960,434...45,997,326

G

sialic acid acetylesterase

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SIAE protein]

NCBI chr 8:45,507,465...45,542,740
Ensembl chr 8:45,507,326...45,542,740

G

signal-induced proliferation-associated 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SIPA1 mRNA

NCBI chr 1:212,367,867...212,379,952
Ensembl chr 1:212,367,867...212,377,497

G

sirtuin 1

multiple interactions
decreases expression

ISO

ADAM17 protein affects the reaction [Dextran Sulfate results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of SIRT1 protein]
Dextran Sulfate results in decreased expression of SIRT1 mRNA; Dextran Sulfate results in decreased expression of SIRT1 protein

PMID:19940103 PMID:24548422

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000

G

sirtuin 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SIRT2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SIRT2 protein]

NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499

G

SKI3 subunit of superkiller complex

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SKIC3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SKIC3 protein]

NCBI chr 2:7,363,417...7,526,351
Ensembl chr 2:7,363,535...7,483,496

G

solute carrier family 10 member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of SLC10A1 mRNA; Dextran Sulfate results in decreased expression of SLC10A1 protein

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944

G

solute carrier family 10 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC10A2 mRNA

NCBI chr16:91,088,089...91,111,025
Ensembl chr16:91,076,423...91,111,025

G

solute carrier family 10 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC10A6 mRNA

NCBI chr14:6,385,348...6,407,532
Ensembl chr14:6,385,537...6,408,894

G

solute carrier family 11 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC11A1 mRNA

NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:83,406,427...83,417,238

G

solute carrier family 12 member 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SLC12A2 protein]

NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470

G

solute carrier family 12 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC12A4 mRNA

NCBI chr19:50,748,268...50,770,217
Ensembl chr19:50,748,279...50,770,259

G

solute carrier family 12 member 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC12A7 mRNA

NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957

G

solute carrier family 13 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC13A1 mRNA

NCBI chr 4:53,534,763...53,612,704
Ensembl chr 4:53,534,768...53,612,704

G

solute carrier family 13 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC13A2 mRNA

NCBI chr10:63,789,874...63,817,441
Ensembl chr10:63,789,876...63,817,184

G

solute carrier family 13 member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC13A5 mRNA

NCBI chr10:57,364,806...57,389,500
Ensembl chr10:57,364,806...57,389,516

G

solute carrier family 15 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC15A1 mRNA

NCBI chr15:104,944,461...104,991,316
Ensembl chr15:104,944,463...104,989,369

G

solute carrier family 15 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC15A4 mRNA

NCBI chr12:34,684,583...34,718,429
Ensembl chr12:34,698,955...34,719,819

G

solute carrier family 16 member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of SLC16A1 mRNA; Dextran Sulfate results in decreased expression of SLC16A1 protein

NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977

G

solute carrier family 16 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC16A3 mRNA

NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903

G

solute carrier family 16 member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC16A8 mRNA

NCBI chr 7:112,698,701...112,702,496
Ensembl chr 7:112,698,701...112,702,496

G

solute carrier family 17 member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC17A5 mRNA

NCBI chr 8:88,274,497...88,309,734
Ensembl chr 8:88,274,721...88,309,664

G

solute carrier family 17 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC17A6 mRNA

NCBI chr 1:110,348,447...110,388,499
Ensembl chr 1:110,348,447...110,388,498

G

solute carrier family 17 member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC17A8 mRNA

NCBI chr 7:25,881,557...25,936,837
Ensembl chr 7:25,881,557...25,935,410

G

solute carrier family 18 member A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC18A1 mRNA

NCBI chr16:25,408,485...25,453,786
Ensembl chr16:25,420,243...25,453,786

G

solute carrier family 1 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC1A2 mRNA

NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249

G

solute carrier family 1 member 5

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SLC1A5 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SLC1A5 protein]

NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054

G

solute carrier family 1 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC1A6 mRNA

NCBI chr 7:11,492,422...11,521,007
Ensembl chr 7:11,492,422...11,553,997

G

solute carrier family 1 member 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC1A7 mRNA

NCBI chr 5:127,959,769...128,003,899
Ensembl chr 5:127,959,769...128,003,899

G

solute carrier family 22 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A1 mRNA

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436

G

solute carrier family 22, member 18

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A18 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SLC22A18 protein]

PMID:29950665 PMID:35362542

NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380

G

solute carrier family 22 (organic cation transporter), member 21

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A21 mRNA

NCBI chr10:38,605,665...38,633,376
Ensembl chr10:38,604,886...38,631,209

G

solute carrier family 22 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A3 mRNA

NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353

G

solute carrier family 22 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of SLC22A4 mRNA

NCBI chr10:38,634,098...38,687,409
Ensembl chr10:38,634,098...38,679,920

G

solute carrier family 22 member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A5 mRNA

NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077

G

solute carrier family 22 member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC22A8 mRNA

NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588

G

solute carrier family 25 member 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC25A10 mRNA

NCBI chr10:105,765,598...105,775,159
Ensembl chr10:106,264,344...106,273,498

G

solute carrier family 25 member 13

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SLC25A13 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SLC25A13 protein]

NCBI chr 4:35,145,721...35,328,403
Ensembl chr 4:35,145,721...35,328,360

G

solute carrier family 25 member 28

increases expression

ISO

Dextran Sulfate results in increased expression of SLC25A28 mRNA

NCBI chr 1:252,480,106...252,491,365
Ensembl chr 1:252,480,128...252,491,342

G

solute carrier family 25 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC25A4 mRNA

NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700

G

solute carrier family 26 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC26A1 mRNA

NCBI chr14:1,180,465...1,190,257
Ensembl chr14:1,184,649...1,190,255

G

solute carrier family 26 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC26A2 mRNA

NCBI chr18:56,918,662...56,937,032
Ensembl chr18:56,923,337...56,937,012

G

solute carrier family 26 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC26A3 mRNA

NCBI chr 6:53,751,415...53,792,300
Ensembl chr 6:53,751,415...53,792,294

G

solute carrier family 26 member 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC26A7 mRNA

NCBI chr 5:32,681,653...32,819,110
Ensembl chr 5:32,684,288...32,818,905

G

solute carrier family 26 member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC26A9 mRNA

NCBI chr13:45,730,022...45,757,662
Ensembl chr13:45,730,082...45,757,660

G

solute carrier family 27 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC27A1 mRNA

NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,313,015...18,330,045

G

solute carrier family 27 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC27A4 mRNA

NCBI chr 3:33,472,903...33,485,824
Ensembl chr 3:33,472,903...33,485,824

G

solute carrier family 28 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC28A3 mRNA

NCBI chr17:6,068,034...6,120,421
Ensembl chr17:6,068,060...6,120,417

G

solute carrier family 29 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC29A2 mRNA

NCBI chr 1:211,756,588...211,764,561
Ensembl chr 1:211,757,000...211,764,560

G

solute carrier family 2 member 1

increases expression

ISO

Dextran Sulfate results in increased expression of SLC2A1 protein

NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742

G

solute carrier family 2 member 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC2A12 mRNA

NCBI chr 1:24,623,558...24,683,577
Ensembl chr 1:24,589,707...24,694,290

G

solute carrier family 2 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC2A3 mRNA

NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186

G

solute carrier family 30 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC30A1 mRNA

NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892

G

solute carrier family 30 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC30A2 mRNA

NCBI chr 5:151,843,451...151,855,674
Ensembl chr 5:151,843,389...151,855,670

G

solute carrier family 30 member 7

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SLC30A7 protein]

NCBI chr 2:206,544,800...206,607,087
Ensembl chr 2:206,544,800...206,607,043

G

solute carrier family 34 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC34A2 mRNA

NCBI chr14:62,123,313...62,153,020
Ensembl chr14:62,123,316...62,143,360

G

solute carrier family 35 member A1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC35A1 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SLC35A1 protein]

PMID:29950665 PMID:35362542

NCBI chr 5:54,021,896...54,044,677
Ensembl chr 5:54,021,896...54,044,677

G

solute carrier family 35 member A3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC35A3 mRNA

NCBI chr 2:207,305,008...207,344,225
Ensembl chr 2:207,307,947...207,344,155

G

solute carrier family 35 member D1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC35D1 mRNA

NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:123,155,407...123,210,073

G

solute carrier family 35 member D2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC35D2 mRNA

NCBI chr17:992,153...1,025,476
Ensembl chr17:993,646...1,025,475

G

solute carrier family 36 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC36A1 mRNA

NCBI chr10:39,819,753...39,858,068
Ensembl chr10:39,825,023...39,858,066

G

solute carrier family 38, member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of SLC38A1 mRNA

NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:129,617,387...129,681,778

G

solute carrier family 38, member 2

increases expression

ISO

Dextran Sulfate results in increased expression of SLC38A2 mRNA

NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619

G

solute carrier family 39 member 10

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC39A10 mRNA

NCBI chr 9:62,331,281...62,454,754
Ensembl chr 9:62,370,598...62,454,747

G

solute carrier family 39 member 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC39A14 mRNA

NCBI chr15:51,786,517...51,833,260
Ensembl chr15:51,786,623...51,833,229

G

solute carrier family 39 member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC39A4 mRNA

NCBI chr 7:110,214,017...110,218,202
Ensembl chr 7:110,214,017...110,218,202

G

solute carrier family 39 member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC39A5 mRNA

NCBI chr 7:1,409,360...1,415,407
Ensembl chr 7:1,409,360...1,414,784

G

solute carrier family 39 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC39A6 mRNA

NCBI chr18:16,139,621...16,160,163
Ensembl chr18:16,135,008...16,160,163

G

solute carrier family 39 member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC39A8 mRNA

NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667

G

solute carrier family 3 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC3A1 mRNA

NCBI chr 6:15,361,037...15,396,695
Ensembl chr 6:15,361,046...15,394,775

G

solute carrier family 40 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC40A1 mRNA

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460

G

solute carrier family 44, member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC44A3 mRNA

NCBI chr 2:209,552,138...209,628,182
Ensembl chr 2:212,236,853...212,312,982

G

solute carrier family 44, member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC44A4 mRNA

NCBI chr20:3,907,737...3,923,911
Ensembl chr20:3,907,737...3,923,854

G

solute carrier family 46 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC46A1 mRNA

NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869

G

solute carrier family 47 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC47A1 mRNA

NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096

G

solute carrier family 47 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC47A2 mRNA

NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425

G

solute carrier family 4 member 1 (Diego blood group)

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC4A1 mRNA

NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258

G

solute carrier family 4 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC4A2 mRNA

NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402

G

solute carrier family 4 member 7

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC4A7 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SLC4A7 protein]

PMID:29950665 PMID:35362542

NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292

G

solute carrier family 51 member A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC51A mRNA

NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539

G

SLC51 subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC51B mRNA

NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109

G

solute carrier family 52 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC52A2 mRNA

NCBI chr 7:110,126,632...110,146,647
Ensembl chr 7:110,143,220...110,158,809

G

solute carrier family 5 member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A1 mRNA

NCBI chr14:81,778,495...81,843,084
Ensembl chr14:81,778,348...81,846,624

G

solute carrier family 5 member 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A11 mRNA

NCBI chr 1:187,166,609...187,226,291
Ensembl chr 1:187,166,811...187,282,848

G

solute carrier family 5 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of SLC5A3 mRNA

NCBI chr11:44,799,787...44,802,233
Ensembl chr11:44,790,297...44,818,157

G

solute carrier family 5 member 8

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A8 mRNA

NCBI chr 7:25,160,280...25,201,185
Ensembl chr 7:25,159,897...25,204,419

G

solute carrier family 5 member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC5A9 mRNA

NCBI chr 5:131,937,368...131,966,405
Ensembl chr 5:131,938,216...131,961,922

G

solute carrier family 6 member 11

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC6A11 mRNA

NCBI chr 4:148,853,557...148,968,895
Ensembl chr 4:148,853,554...148,969,019

G

solute carrier family 6 member 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC6A12 mRNA

NCBI chr 4:156,257,518...156,275,870
Ensembl chr 4:156,254,208...156,275,879

G

solute carrier family 6 member 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A14 mRNA

NCBI chr X:117,109,063...117,169,522
Ensembl chr X:117,108,947...117,169,828

G

solute carrier family 6 member 19

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A19 mRNA

NCBI chr 1:31,414,744...31,434,932
Ensembl chr 1:31,414,744...31,433,517

G

solute carrier family 6 member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC6A2 mRNA

NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348

G

solute carrier family 6 member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A3 mRNA

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962

G

solute carrier family 6 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC6A6 mRNA

NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032

G

solute carrier family 7 member 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC7A5 mRNA

NCBI chr19:66,843,808...66,872,412
Ensembl chr19:66,843,808...66,872,412

G

solute carrier family 7 member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC7A6 mRNA

NCBI chr19:50,982,459...51,010,140
Ensembl chr19:50,984,132...51,010,134

G

solute carrier family 7 member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC7A9 mRNA

NCBI chr 1:97,246,253...97,269,546
Ensembl chr 1:97,247,547...97,269,543

G

solute carrier family 8 member A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC8A1 mRNA

NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964

G

solute carrier family 8 member A3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC8A3 mRNA

NCBI chr 6:106,605,611...106,739,208
Ensembl chr 6:106,605,621...106,721,412

G

solute carrier family 9 member A2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC9A2 mRNA

NCBI chr 9:50,427,612...50,510,043
Ensembl chr 9:50,426,798...50,510,040

G

solute carrier family 9 member A3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC9A3 mRNA

NCBI chr 1:30,953,215...30,996,209
Ensembl chr 1:30,953,216...30,996,002

G

solute carrier family 9 member A7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC9A7 mRNA

NCBI chr X:4,767,578...4,948,602
Ensembl chr X:4,767,915...4,948,602

G

solute carrier organic anion transporter family, member 1a4

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLCO1A4 mRNA
Dextran Sulfate results in decreased expression of SLCO1A4 mRNA

PMID:29950665 PMID:35093514

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816

G

solute carrier organic anion transporter family, member 2b1

multiple interactions
decreases expression
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLCO2B1 mRNA
Dextran Sulfate results in decreased expression of SLCO2B1 mRNA; Dextran Sulfate results in decreased expression of SLCO2B1 protein
Dextran Sulfate results in increased expression of SLCO2B1 mRNA; Dextran Sulfate results in increased expression of SLCO2B1 protein
Rifampin inhibits the reaction [Dextran Sulfate results in increased expression of SLCO2B1 mRNA]

PMID:29950665 PMID:38423481 PMID:38844255

NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279

G

solute carrier organic anion transporter family, member 3a1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLCO3A1 mRNA

NCBI chr 1:137,516,037...137,797,836
Ensembl chr 1:137,505,158...137,797,836

G

SMAD family member 4

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SMAD4 protein]

NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684

G

SWI/SNF related BAF chromatin remodeling complex subunit B1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SMARCB1 protein]

NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055

G

SWI/SNF related BAF chromatin remodeling complex subunit E1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SMARCE1 protein]

NCBI chr10:84,655,468...84,678,259
Ensembl chr10:84,655,468...84,676,185

G

smoothened, frizzled class receptor

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SMO mRNA

NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:59,311,041...59,341,281

G

spermine oxidase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SMOX mRNA

NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170
Ensembl chr X:139,184,798...139,220,170

G

sphingomyelin phosphodiesterase 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SMPD2 mRNA
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD2 mRNA]

NCBI chr20:46,568,627...46,571,741
Ensembl chr20:46,568,629...46,571,741

G

sphingomyelin phosphodiesterase 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SMPD3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SMPD3 protein]

NCBI chr19:51,072,209...51,155,639
Ensembl chr19:51,072,209...51,085,936

G

sphingomyelin phosphodiesterase 4

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SMPD4 mRNA
Fenofibrate promotes the reaction [Dextran Sulfate results in decreased expression of SMPD4 mRNA]

NCBI chr11:96,866,805...96,890,520
Ensembl chr11:96,866,805...96,890,520

G

sphingomyelin phosphodiesterase, acid-like 3A

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SMPDL3A protein]

NCBI chr20:37,679,004...37,701,979
Ensembl chr20:37,678,964...37,704,260

G

snail family transcriptional repressor 1

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SNAI1 protein

NCBI chr 3:176,667,476...176,671,965

G

small nucleolar RNA, C/D box 118

increases expression

ISO

Dextran Sulfate results in increased expression of SNORD118 mRNA

NCBI chr10:54,273,655...54,273,790
Ensembl chr10:54,273,655...54,273,790

G

small nuclear ribonucleoprotein polypeptide F

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SNRPF protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SNRPF protein]

NCBI chr 7:30,017,460...30,024,162
Ensembl chr 7:30,017,460...30,024,162

G

small nuclear ribonucleoprotein polypeptide G

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SNRPG protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of SNRPG protein]

NCBI chr 4:120,369,676...120,377,263
Ensembl chr 4:120,369,685...120,377,261
Ensembl chr X:120,369,685...120,377,261

G

sorting nexin 9

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SNX9 protein]

NCBI chr 1:48,827,061...48,915,215
Ensembl chr 1:48,830,053...48,915,214

G

superoxide dismutase 2

multiple interactions
decreases expression

ISO

formononetin inhibits the reaction [Dextran Sulfate results in decreased expression of SOD2 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

SRY-box transcription factor 4

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of SOX4 mRNA

NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024

G

SRY-box transcription factor 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SOX9 mRNA

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

secreted protein acidic and cysteine rich

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SPARC mRNA

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268

G

sphingosine kinase 1

multiple interactions
increases expression

ISO
EXP

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SPHK1 mRNA
Hesperidin inhibits the reaction [Dextran Sulfate results in increased expression of SPHK1 protein]

PMID:29950665 PMID:30811821

NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082

G

serine peptidase inhibitor, Kazal type 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SPINK1 protein]

NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545

G

sialophorin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SPN mRNA

NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:191,178,096...191,187,852

G

secreted phosphoprotein 1

multiple interactions
decreases expression
increases expression

ISO

Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of SPP1 mRNA]
Dextran Sulfate results in decreased expression of SPP1 protein

PMID:32033881 PMID:35999755

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

small proline-rich protein 1A

increases expression

ISO

Dextran Sulfate results in increased expression of SPRR1A mRNA

NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991

G

spectrin, beta, non-erythrocytic 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of SPTBN1 protein

NCBI chr14:108,042,629...108,217,884
Ensembl chr14:108,042,629...108,217,836

G

sequestosome 1

multiple interactions
increases expression
decreases expression

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]; [Dextran Sulfate co-treated with 6-formylindolo(3,2-b)carbazole] results in decreased expression of SQSTM1 protein; [Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein; [HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein; biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of SQSTM1 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein]; Leucine inhibits the reaction [[Dextran Sulfate co-treated with alpinetin] results in decreased expression of SQSTM1 protein]; Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]
dorsomorphin inhibits the reaction [Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]]; Nicotine promotes the reaction [Dextran Sulfate results in decreased expression of SQSTM1 protein]

PMID:27611972 PMID:31676321 PMID:31926917 PMID:38648921

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750

G

steroid 5 alpha-reductase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SRD5A2 mRNA

NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:27,178,079...27,217,588

G

SLIT-ROBO Rho GTPase activating protein 3

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SRGAP3 mRNA
Dextran Sulfate results in decreased expression of SRGAP3 mRNA

PMID:29950665 PMID:35093514

NCBI chr 4:147,391,082...147,626,407
Ensembl chr 4:147,395,880...147,625,713

G

signal recognition particle 9

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of SRP9 protein]

NCBI chr13:96,364,253...96,372,393
Ensembl chr13:96,364,298...96,373,257

G

serine/arginine repetitive matrix 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SRRM2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SRRM2 protein]

NCBI chr10:13,320,059...13,353,337
Ensembl chr10:13,320,059...13,353,337

G

serine and arginine rich splicing factor 11

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SRSF11 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SRSF11 protein]

NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499

G

serine and arginine rich splicing factor 4

increases expression

ISO

Dextran Sulfate results in increased expression of SRSF4 mRNA

NCBI chr 5:149,345,538...149,373,309
Ensembl chr 5:149,345,422...149,374,609

G

somatostatin receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SSTR1 mRNA

NCBI chr 6:81,567,237...81,571,759
Ensembl chr 6:81,566,850...81,571,992

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of ST3GAL3 mRNA

NCBI chr 5:136,755,780...136,958,081
Ensembl chr 5:136,755,678...136,955,987

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ST3GAL6 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ST3GAL6 protein]

PMID:29950665 PMID:35362542

NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720

G

steroidogenic acute regulatory protein

decreases expression

ISO

Dextran Sulfate results in decreased expression of STAR mRNA

NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447

G

StAR-related lipid transfer domain containing 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STARD5 mRNA

NCBI chr 1:147,015,304...147,025,170
Ensembl chr 1:147,015,299...147,026,351

G

signal transducer and activator of transcription 1

multiple interactions
decreases expression
increases phosphorylation

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of STAT1 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT1 protein]

PMID:31737179 PMID:35362542

NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346

G

signal transducer and activator of transcription 3

multiple interactions
increases phosphorylation
increases expression

EXP
ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STAT3 protein]
Dextran Sulfate results in increased phosphorylation of STAT3 protein
Dextran Sulfate results in increased expression of STAT3 mRNA; Dextran Sulfate results in increased expression of STAT3 protein
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]; 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of and results in increased phosphorylation of STAT3 protein; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; CEP 33779 inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of and results in increased phosphorylation of STAT3 protein]; Dextran Sulfate results in increased expression of and results in increased phosphorylation of STAT3 protein; Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein; Erianin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; fucoxanthin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased phosphorylation of STAT3 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased phosphorylation of STAT3 protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of STAT3 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of and results in increased activity of STAT3 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased phosphorylation of STAT3 protein]; xianglian pill inhibits the reaction [Dextran Sulfate results in increased expression of STAT3 mRNA]

PMID:19028472 PMID:20155626 PMID:22334590 PMID:25026504 PMID:26074695 More...

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

STEAP family member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of STEAP1 mRNA

NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:29,231,753...29,242,317

G

STEAP2 metalloreductase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of STEAP2 mRNA

NCBI chr 4:29,302,487...29,323,006
Ensembl chr 4:29,303,381...29,330,620

G

stromal interaction molecule 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of STIM1 mRNA

NCBI chr 1:166,067,450...166,230,733
Ensembl chr 1:166,067,962...166,233,108

G

stress-induced phosphoprotein 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of STIP1 protein

NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654

G

serine/threonine kinase 4

multiple interactions

ISO

[RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in decreased activity of STK4 protein

NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:173,165,083...173,247,134

G

stimulated by retinoic acid 8

increases expression

ISO

Dextran Sulfate results in increased expression of STRA8 mRNA

NCBI chr 4:64,568,580...64,591,914
Ensembl chr 4:64,568,706...64,591,911

G

syntaxin 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of STX1A mRNA

NCBI chr12:27,278,517...27,306,547
Ensembl chr12:27,278,517...27,306,471

G

SUB1 regulator of transcription

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SUB1 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SUB1 protein]

NCBI chr 2:62,735,379...62,747,545
Ensembl chr 2:62,732,736...62,747,679

G

succinate-CoA ligase GDP-forming subunit beta

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SUCLG2 mRNA

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296

G

sulfotransferase family 1B member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549

G

sulfotransferase family 1C member 2A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SULT1C2 mRNA

NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132

G

sulfotransferase family 1E member 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of SULT1E1 mRNA

NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716

G

Sad1 and UNC84 domain containing 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SUN1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SUN1 protein]

NCBI chr12:20,510,230...20,555,123
Ensembl chr12:20,490,861...20,555,240

G

sulfite oxidase

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of SUOX protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of SUOX protein]

NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235

G

sushi domain containing 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SUSD2 protein]

NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,016,907...13,024,264

G

SUV39H1 histone lysine methyltransferase

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SUV39H1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]

NCBI chr X:17,093,059...17,105,942
Ensembl chr X:17,092,986...17,105,942

G

SUV39H1 histone lysine methyltransferase, pseudogene 1

multiple interactions
increases expression

ISO

2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in increased expression of SUV39H1 protein]

NCBI chr X:146,828,818...146,831,485

G

supervillin

decreases expression

ISO

Dextran Sulfate results in decreased expression of SVIL mRNA

NCBI chr17:57,343,910...57,539,508
Ensembl chr17:57,343,910...57,462,660

G

spectrin repeat containing nuclear envelope protein 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of SYNE2 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SYNE2 protein]

NCBI chr 6:100,272,729...100,586,364
Ensembl chr 6:100,272,729...100,583,723

G

synoviolin 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of SYVN1 protein]

NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:212,768,907...212,776,457

G

trace amine-associated receptor 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TAAR5 mRNA

NCBI chr 1:21,469,923...21,470,936
Ensembl chr 1:23,289,163...23,290,176

G

tachykinin, precursor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TAC1 mRNA

NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546

G

tachykinin receptor 1

affects response to substance
multiple interactions

ISO

TACR1 protein affects the susceptibility to Dextran Sulfate
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TACR1 mRNA

PMID:20889569 PMID:29950665

NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492

G

tachykinin receptor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TACR2 mRNA

NCBI chr20:30,751,645...30,766,181
Ensembl chr20:30,751,557...30,766,180

G

TATA-box binding protein associated factor 15

increases expression

ISO

Dextran Sulfate results in increased expression of TAF15 mRNA

NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,770,430...68,802,458

G

T-cell activation RhoGTPase activating protein

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TAGAP mRNA

NCBI chr 1:49,575,750...49,584,747
Ensembl chr 1:49,575,750...49,583,838

G

transgelin

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of TAGLN protein

NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563

G

transgelin 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of TAGLN2 protein
[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of TAGLN2 protein

NCBI chr13:87,499,350...87,506,328
Ensembl chr13:87,499,394...87,506,330

G

transporter 1, ATP binding cassette subfamily B member

increases expression
decreases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TAP1 mRNA
Dextran Sulfate results in decreased expression of TAP1 protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TAP1 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of TAP1 protein]

PMID:23894361 PMID:29950665 PMID:35362542

NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810

G

taste 1 receptor member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of TAS1R2 mRNA

NCBI chr 5:157,192,799...157,208,937
Ensembl chr 5:157,192,799...157,208,937

G

taste 1 receptor member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TAS1R3 mRNA

NCBI chr 5:171,750,937...171,754,993
Ensembl chr 5:171,750,937...171,754,993

G

taste receptor, type 2, member 118

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TAS2R118 mRNA

NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:53,414,815...53,415,714

G

taste receptor, type 2, member 137

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TAS2R137 mRNA

NCBI chr 4:69,279,276...69,286,935
Ensembl chr 4:70,251,091...70,252,041

G

taste receptor, type 2, member 145

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TAS2R131 mRNA

NCBI chr 4:166,138,007...166,138,957
Ensembl chr 4:167,869,358...167,870,544

G

TBC1 domain family, member 15

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of TBC1D15 protein]

NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303

G

tubulin folding cofactor C

increases expression

ISO

Dextran Sulfate results in increased expression of TBCC mRNA

NCBI chr 9:14,098,855...14,100,043
Ensembl chr 9:21,595,615...21,597,842

G

transducin (beta)-like 2

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TBL2 protein]

NCBI chr12:27,154,150...27,168,446
Ensembl chr12:27,154,150...27,168,446

G

T-box transcription factor 21

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TBX21 mRNA
Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of TBX21 mRNA]

NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253

G

thromboxane A synthase 1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TBXAS1 mRNA
Dextran Sulfate results in increased expression of TBXAS1 protein

PMID:29950665 PMID:30489199

NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969

G

TRPM8 channel-associated factor 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of TCAF1 mRNA

NCBI chr 4:72,589,710...72,639,304
Ensembl chr 4:72,589,710...72,639,475

G

TRPM8 channel-associated factor 2

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TCAF2 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TCAF2 protein]

G

titin-cap

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TCAP mRNA

NCBI chr10:83,878,006...83,879,174
Ensembl chr10:83,876,939...83,879,483

G

transcription factor 7

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of TCF7 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of TCF7 mRNA]

NCBI chr10:36,924,363...36,954,279
Ensembl chr10:36,924,363...36,954,279

G

trichoplein, keratin filament binding

increases expression

ISO

Dextran Sulfate results in increased expression of TCHP mRNA

NCBI chr12:47,538,520...47,553,895
Ensembl chr12:47,538,520...47,553,836

G

transferrin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRF mRNA

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

trefoil factor 3

increases expression

ISO

Dextran Sulfate results in increased expression of TFF3 mRNA

NCBI chr20:9,194,623...9,199,333
Ensembl chr20:9,194,626...9,199,333

G

transferrin receptor

increases expression

ISO

Dextran Sulfate results in increased expression of TFRC protein

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta 1

multiple interactions
decreases expression
increases expression

ISO
EXP

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein; [Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein]; obeticholic acid inhibits the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TGFB1 protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of TGFB1 protein]
kappa-casein glycomacropeptide inhibits the reaction [Dextran Sulfate results in increased expression of TGFB1 mRNA]

PMID:20881082 PMID:25026504 PMID:26074695 PMID:35439472

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor, beta 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TGFB3 mRNA

NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946

G

transglutaminase 3

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TGM3 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TGM3 protein]

NCBI chr 3:137,681,809...137,717,219
Ensembl chr 3:137,681,809...137,717,219

G

thrombomodulin

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of THBD mRNA
Dextran Sulfate results in decreased expression of THBD mRNA

PMID:29950665 PMID:35093514

NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582

G

thrombospondin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of THBS1 mRNA

NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402

G

thrombospondin 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of THBS4 mRNA

NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:25,718,219...25,761,369

G

Thy-1 cell surface antigen

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of THY1 protein]

NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540

G

TIMP metallopeptidase inhibitor 1

multiple interactions
increases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TIMP1 mRNA; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of TIMP1 mRNA]

PMID:29950665 PMID:32033881

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

TIMP metallopeptidase inhibitor 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TIMP2 mRNA

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214

G

TIMP metallopeptidase inhibitor 3

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TIMP3 mRNA; ADAM17 protein affects the reaction [Dextran Sulfate results in decreased expression of TIMP3 mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in decreased expression of TIMP3 mRNA]

PMID:24548422 PMID:29950665

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

tight junction protein 1

multiple interactions
decreases expression

ISO

[Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TJP1 protein; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; daphnetin inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; fucoxanthin inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; HU 211 inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 mRNA]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 mRNA]; isomaltulose inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; nitazoxanide inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; nuciferine inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein]; obeticholic acid promotes the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TJP1 protein]
Dextran Sulfate results in decreased expression of TJP1 mRNA; Dextran Sulfate results in decreased expression of TJP1 protein

PMID:27995407 PMID:35439472 PMID:35670535 PMID:35894244 PMID:36281492 More...

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

thymidine kinase 1

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TK1 mRNA; alfacalcidol inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TK1 mRNA]

NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228

G

transketolase

decreases expression

ISO

Dextran Sulfate results in decreased expression of TKT mRNA

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431

G

tolloid-like 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TLL1 mRNA

NCBI chr16:30,275,492...30,476,673
Ensembl chr16:30,275,492...30,475,886

G

talin 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TLN1 mRNA

NCBI chr 5:62,583,730...62,613,687
Ensembl chr 5:62,583,731...62,613,687

G

toll-like receptor 2

multiple interactions

ISO

Dextran Sulfate promotes the reaction [TLR2 protein binds to MYD88 protein]; flavokawain B inhibits the reaction [Dextran Sulfate promotes the reaction [TLR2 protein binds to MYD88 protein]]

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194

G

toll-like receptor 4

multiple interactions
affects response to substance
increases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; [Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TLR4 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TLR4 mRNA; Dextran Sulfate affects the reaction [TLR4 protein affects the expression of IL6 protein]; Dextran Sulfate affects the reaction [TLR4 protein affects the expression of TNF protein]; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; Lipopolysaccharides inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; obeticholic acid inhibits the reaction [[Dietary Fats co-treated with Dextran Sulfate] results in increased expression of TLR4 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of CSF2 protein]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of IL6 protein]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of TNF protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL17A protein]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]]
TLR4 protein affects the susceptibility to Dextran Sulfate

PMID:21359540 PMID:27995407 PMID:29950665 PMID:31442584 PMID:32272095 More...

NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007

G

toll-like receptor 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TLR7 mRNA

NCBI chr X:30,644,324...30,670,796
Ensembl chr X:30,644,355...30,672,151

G

transmembrane protein 109

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of TMEM109 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of TMEM109 protein]

NCBI chr 1:216,944,516...216,955,091
Ensembl chr 1:216,944,519...216,955,138

G

transmembrane protein 164

decreases expression

ISO

Dextran Sulfate results in decreased expression of TMEM164 mRNA

NCBI chr X:111,084,830...111,245,419
Ensembl chr X:111,085,712...111,245,417

G

transmembrane protein 191C

increases expression

ISO

Dextran Sulfate results in increased expression of TMEM191C mRNA

NCBI chr11:83,726,155...83,728,926
Ensembl chr11:97,229,419...97,237,082

G

transmembrane protein 252

increases expression

ISO

Dextran Sulfate results in increased expression of TMEM252 mRNA

NCBI chr 1:231,743,396...231,748,360
Ensembl chr 1:231,743,233...231,748,358

G

transmembrane protein 30B

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TMEM30B protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TMEM30B protein]

NCBI chr 6:97,987,471...97,990,546
Ensembl chr 6:97,987,130...97,991,170

G

thymosin, beta 10

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of TMSB10 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of TMSB10 protein]

NCBI chr 4:106,568,080...106,569,210

G

thymosin beta 4, X-linked

decreases expression

ISO

Dextran Sulfate results in decreased expression of TMSB4X protein

NCBI chr X:30,761,611...30,763,612
Ensembl chr X:30,761,612...30,763,613

G

thiol methyltransferase 1B

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TMT1B protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TMT1B protein]

NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980

G

tumor necrosis factor

multiple interactions
increases expression
affects expression
increases secretion

ISO
EXP

(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; 2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; 7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; [Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNF protein; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNF mRNA; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNF protein; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of TNF protein; [IL17A protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; ADAM17 protein affects the reaction [Dextran Sulfate results in increased expression of TNF protein]; Allura Red AC Dye promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; anandamide inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; asperuloside inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]; biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; bisphenol A promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]]; CD14 protein inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; celastrol promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; Chlorpyrifos promotes the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Coumarins inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; daphnetin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Dextran Sulfate affects the reaction [TLR4 protein affects the expression of TNF protein]; Dextran Sulfate inhibits the reaction [[Ampicillin co-treated with Vancomycin co-treated with Neomycin co-treated with Metronidazole] results in decreased expression of TNF protein]; Dextran Sulfate inhibits the reaction [Polymyxin B results in decreased expression of TNF protein]; Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]; Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein; dihydrotanshinone I inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]; DUSP1 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; DUSP1 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Fatty Acids, Omega-3 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; geraniol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; gingerenone A inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; gingerol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; IRF4 protein inhibits the reaction [BCL6 protein inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]]; IRF4 protein promotes the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNF protein]; isomaltulose inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; isovitexin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; ligustilide inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Lipopolysaccharides promotes the reaction [Dextran Sulfate results in increased expression of TNF protein]; mangiferin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; MIF protein affects the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Minocycline inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; NFE2L2 protein affects the reaction [Butylated Hydroxyanisole affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; NFE2L2 protein affects the reaction [Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]]; Nicotine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; nuciferine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Polymyxin B inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Qingdai compound inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Resveratrol affects the reaction [Dextran Sulfate affects the expression of TNF protein]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; SB 203580 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of TNF protein]; thiamet G promotes the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; TLR4 protein affects the reaction [Dextran Sulfate results in increased expression of TNF protein]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]]; TLR4 protein affects the reaction [HU 211 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Ursodeoxycholic Acid inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNF mRNA]
Dextran Sulfate results in increased expression of TNF mRNA; Dextran Sulfate results in increased expression of TNF protein
[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNF protein; [bisphenol A diglycidyl ether co-treated with Dextran Sulfate co-treated with Rosiglitazone] results in increased expression of TNF protein; [bisphenol A diglycidyl ether co-treated with Dextran Sulfate] results in increased expression of TNF protein; banxia xiexin decoction inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; celastrol inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; celastrol promotes the reaction [N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]]; Melatonin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNF protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Olmesartan Medoxomil inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; palmatine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Rosiglitazone inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]

PMID:12105854 PMID:16774945 PMID:17438113 PMID:19028472 PMID:19285099 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 11A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNFRSF11A mRNA

NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257

G

TNF receptor superfamily member 12A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFRSF12A mRNA

NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704

G

TNF receptor superfamily member 18

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFRSF18 mRNA

NCBI chr 5:171,901,734...171,904,578
Ensembl chr 5:171,901,717...171,904,576

G

TNF receptor superfamily member 1A

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFRSF1A mRNA

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF receptor superfamily member 1B

increases expression

ISO

Dextran Sulfate results in increased expression of TNFRSF1B mRNA

NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411

G

TNF receptor superfamily member 8

multiple interactions
affects response to substance

ISO

[TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IFNG protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL10 protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; [TNFRSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL4 protein

NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:162,406,387...162,451,620

G

TNF superfamily member 12

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFSF12 mRNA

NCBI chr10:54,902,616...54,912,628
Ensembl chr10:54,902,616...54,911,913

G

TNF superfamily member 14

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFSF14 mRNA

NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,155,270...2,160,191

G

TNF superfamily member 15

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNFSF15 mRNA

NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:82,150,376...82,171,882

G

TNF superfamily member 8

increases expression
multiple interactions
affects response to substance

ISO

Dextran Sulfate results in increased expression of TNFSF8 protein
[TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL1B protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of IL6 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the expression of TNF protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IFNG protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL10 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL17A protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL2 protein; [TNFSF8 protein affects the susceptibility to Dextran Sulfate] which affects the secretion of IL4 protein

NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:82,266,436...82,292,858

G

TNF superfamily member 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNFSF9 mRNA

NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339

G

troponin C1, slow skeletal and cardiac type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNC1 mRNA

NCBI chr16:6,408,607...6,412,070
Ensembl chr16:6,408,607...6,412,070

G

troponin C2, fast skeletal type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNC2 mRNA

NCBI chr 3:173,932,611...173,935,339
Ensembl chr 3:173,932,611...173,935,339

G

troponin I1, slow skeletal type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TNNI1 mRNA

NCBI chr13:49,781,529...49,793,385
Ensembl chr13:49,780,951...49,793,390

G

troponin I2, fast skeletal type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNI2 mRNA

NCBI chr 1:206,882,358...207,027,034
Ensembl chr 1:207,024,416...207,027,038

G

troponin T3, fast skeletal type

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNT3 mRNA

NCBI chr 1:207,082,014...207,099,014
Ensembl chr 1:207,081,812...207,099,423

G

toll interacting protein

multiple interactions
decreases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in decreased expression of TOLLIP protein]; Mesalamine inhibits the reaction [Dextran Sulfate results in decreased expression of TOLLIP protein]

NCBI chr 1:206,391,120...206,413,809
Ensembl chr 1:206,380,308...206,411,988

G

translocase of outer mitochondrial membrane 5

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of TOMM5 protein]

NCBI chr 5:64,158,026...64,160,857

G

translocase of outer mitochondrial membrane 7

increases expression

ISO

Dextran Sulfate results in increased expression of TOMM7 mRNA

NCBI chr 4:12,197,503...12,204,344
Ensembl chr 4:12,197,491...12,204,343

G

tumor protein p53

increases expression

ISO

Dextran Sulfate results in increased expression of TRP53 protein

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

two pore segment channel 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TPCN1 mRNA

NCBI chr12:41,633,399...41,690,200
Ensembl chr12:41,633,398...41,690,200

G

tryptophan hydroxylase 1

multiple interactions
increases expression

ISO

Granisetron inhibits the reaction [Serotonin inhibits the reaction [Dextran Sulfate results in increased expression of TPH1 protein]]; Serotonin inhibits the reaction [Dextran Sulfate results in increased expression of TPH1 protein]

NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484

G

triosephosphate isomerase 1

increases expression
decreases expression

ISO

Dextran Sulfate results in increased expression of TPI1 mRNA
Dextran Sulfate results in decreased expression of TPI1 protein

PMID:35093514 PMID:35999755

NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:159,301,562...159,305,413

G

tropomyosin 2

multiple interactions
decreases expression

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of TPM2 mRNA
Dextran Sulfate results in decreased expression of TPM2 protein

PMID:26271895 PMID:35999755

NCBI chr 5:62,566,712...62,576,066
Ensembl chr 5:62,566,652...62,575,726

G

tropomyosin 3

decreases expression

ISO

Dextran Sulfate results in decreased expression of TPM3 protein

NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:177,814,883...177,842,660

G

tropomyosin 4

decreases expression

ISO

Dextran Sulfate results in decreased expression of TPM4 protein

NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494

G

thiopurine S-methyltransferase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TPMT mRNA

NCBI chr17:17,850,308...17,868,976
Ensembl chr17:17,850,279...17,868,976

G

tryptase beta 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TPSB2 mRNA

NCBI chr10:14,886,310...14,888,102
Ensembl chr10:14,886,360...14,888,100

G

tumor protein, translationally-controlled 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of TPT1 protein

NCBI chr15:57,562,217...57,568,968
Ensembl chr15:57,566,067...57,569,554

G

TRAF3 interacting protein 1

increases expression

ISO

Dextran Sulfate results in increased expression of TRAF3IP1 mRNA

NCBI chr 9:99,521,176...99,557,966
Ensembl chr 9:99,521,179...99,557,963

G

TNF receptor associated factor 6

multiple interactions
increases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TRAF6 protein]; Sulfasalazine inhibits the reaction [Dextran Sulfate results in increased expression of TRAF6 protein]

NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328

G

tetratricopeptide repeat and ankyrin repeat containing 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of TRANK1 mRNA

NCBI chr 8:120,153,381...120,233,879
Ensembl chr 8:120,154,362...120,234,087

G

triggering receptor expressed on myeloid cells 2

multiple interactions
increases expression

ISO

huanglian-jie-du decoction inhibits the reaction [Dextran Sulfate results in increased expression of TREM2 protein]

NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779

G

thyrotropin releasing hormone

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of TRH mRNA

NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:126,299,236...126,301,762

G

tribbles pseudokinase 2

decreases expression

ISO

Dextran Sulfate results in decreased expression of TRIB2 mRNA

NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:44,274,762...44,299,094

G

tripartite motif-containing 25

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRIM25 mRNA

NCBI chr10:74,310,024...74,328,473
Ensembl chr10:74,310,022...74,331,716

G

tripartite motif-containing 41

increases expression

ISO

Dextran Sulfate results in increased expression of TRIM41 mRNA

NCBI chr10:33,676,348...33,687,432
Ensembl chr10:33,676,348...33,687,432

G

telomerase RNA component interacting RNase

increases expression

ISO

Dextran Sulfate results in increased expression of TRIR mRNA

NCBI chr19:40,029,952...40,033,368
Ensembl chr19:40,029,952...40,033,368

G

transient receptor potential cation channel, subfamily C, member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPC3 mRNA

NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823

G

transient receptor potential cation channel, subfamily C, member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPC6 mRNA

NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304

G

transient receptor potential cation channel, subfamily C, member 7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPC7 mRNA

NCBI chr17:7,707,954...7,839,064
Ensembl chr17:7,714,505...7,838,745

G

transient receptor potential cation channel, subfamily M, member 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] affects the expression of TRPM1 mRNA

NCBI chr 1:127,130,686...127,247,219
Ensembl chr 1:127,130,686...127,247,391

G

transient receptor potential cation channel, subfamily M, member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPM4 mRNA

NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:104,918,462...104,948,653

G

transient receptor potential cation channel, subfamily M, member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TRPM6 mRNA

NCBI chr 1:225,559,528...225,747,106
Ensembl chr 1:225,576,872...225,747,108

G

transient receptor potential cation channel, subfamily M, member 8

increases expression

ISO

Dextran Sulfate results in increased expression of TRPM8 mRNA

NCBI chr 9:96,315,567...96,437,959
Ensembl chr 9:96,351,681...96,436,617

G

transient receptor potential cation channel, subfamily V, member 1

affects expression
multiple interactions

ISO

Dextran Sulfate affects the expression of TRPV1 protein
[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV1 mRNA

PMID:18687398 PMID:29950665

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021

G

transient receptor potential cation channel, subfamily V, member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV2 mRNA

NCBI chr10:47,772,223...47,797,956
Ensembl chr10:47,764,839...47,793,533

G

transient receptor potential cation channel, subfamily V, member 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV4 mRNA

NCBI chr12:47,599,161...47,638,143
Ensembl chr12:47,599,035...47,638,143

G

transient receptor potential cation channel, subfamily V, member 6

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRPV6 mRNA

NCBI chr 4:71,474,006...71,489,667
Ensembl chr 4:71,474,007...71,489,671

G

trypsin 5

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TRY5 mRNA

NCBI chr 4:71,180,421...71,183,695

G

TSC complex subunit 2

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of TSC2 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]]; alpinetin inhibits the reaction [Dextran Sulfate results in decreased expression of TSC2 protein]

NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600

G

TSC22 domain family, member 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TSC22D3 mRNA

NCBI chr X:109,006,410...109,066,389
Ensembl chr X:109,006,420...109,015,519

G

Ts translation elongation factor, mitochondrial

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TSFM protein]

NCBI chr 7:64,714,330...64,750,106
Ensembl chr 7:64,714,036...64,750,171

G

testis-specific serine kinase substrate

increases expression

ISO

Dextran Sulfate results in increased expression of TSKS mRNA

NCBI chr 1:104,550,790...104,578,147
Ensembl chr 1:104,550,897...104,578,145

G

translin-associated factor X

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of TSNAX protein]

NCBI chr19:69,873,210...69,887,244
Ensembl chr19:69,872,987...69,887,224

G

thiosulfate sulfurtransferase

multiple interactions
decreases expression

ISO

Dextran Sulfate affects the activity of and results in decreased expression of TST protein
Dextran Sulfate results in decreased expression of TST mRNA

NCBI chr 7:111,828,557...111,836,980
Ensembl chr 7:111,828,558...111,837,116

G

titin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TTN mRNA

NCBI chr 3:82,059,648...82,332,130
Ensembl chr 3:82,059,648...82,332,171

G

transthyretin

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TTR mRNA

NCBI chr18:12,216,684...12,225,972
Ensembl chr18:12,216,732...12,225,969

G

tubulin, alpha 1A

decreases expression

ISO

Dextran Sulfate results in decreased expression of TUBA1A protein

NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035

G

tubulin, alpha 4A

decreases expression

ISO

Dextran Sulfate results in decreased expression of TUBA4A protein

NCBI chr 9:84,158,871...84,174,041
Ensembl chr 9:84,158,280...84,162,584

G

tubulin, beta 1 class VI

decreases expression

ISO

Dextran Sulfate results in decreased expression of TUBB1 protein

NCBI chr 3:183,666,189...183,675,656
Ensembl chr 3:183,666,242...183,674,795

G

tubulin, beta 6 class V

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TUBB6 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of TUBB6 protein]

NCBI chr18:63,213,287...63,222,926
Ensembl chr18:63,213,279...63,224,303

G

thioredoxin domain containing 9

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of TXNDC9 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of TXNDC9 protein]

NCBI chr 9:47,707,628...47,717,761
Ensembl chr 9:47,707,231...47,880,085

G

thymidylate synthetase

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of TYMS mRNA

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097

G

transmembrane immune signaling adaptor Tyrobp

multiple interactions
increases expression

ISO

huanglian-jie-du decoction inhibits the reaction [Dextran Sulfate results in increased expression of TYROBP mRNA]; huanglian-jie-du decoction inhibits the reaction [Dextran Sulfate results in increased expression of TYROBP protein]
Dextran Sulfate results in increased expression of TYROBP mRNA; Dextran Sulfate results in increased expression of TYROBP protein

NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299

G

UDP-N-acetylglucosamine pyrophosphorylase 1 like 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of UAP1L1 protein
Erianin inhibits the reaction [Dextran Sulfate results in increased expression of UAP1L1 protein]

NCBI chr 3:28,570,854...28,579,766
Ensembl chr 3:28,573,358...28,578,630

G

ubiquitin-like modifier activating enzyme 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of UBA1 protein

NCBI chr X:4,062,216...4,084,192
Ensembl chr X:4,062,182...4,084,246

G

ubiquitin-like modifier activating enzyme 7

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of UBA7 mRNA; evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of UBA7 protein]

PMID:29950665 PMID:35362542

NCBI chr 8:117,543,902...117,552,709
Ensembl chr 8:117,543,957...117,556,142

G

ubiquitin-conjugating enzyme E2D 3

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of UBE2D3 protein]

NCBI chr 2:226,543,194...226,571,001
Ensembl chr 2:226,540,531...226,573,144

G

ubiquitin-like domain containing CTD phosphatase 1

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of UBLCP1 protein]

NCBI chr10:29,447,081...29,462,446
Ensembl chr10:29,447,081...29,462,386

G

ubiquilin 1

multiple interactions
decreases expression

ISO

Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of UBQLN1 protein]

NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,444,124...6,482,499

G

upstream binding transcription factor

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of UBTF protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of UBTF protein]

NCBI chr10:87,758,346...87,775,377
Ensembl chr10:87,758,346...87,773,088

G

uridine-cytidine kinase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of UCK2 mRNA

NCBI chr13:81,913,732...81,971,036
Ensembl chr13:81,916,818...81,971,091

G

UDP-glucose 6-dehydrogenase

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGDH mRNA

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629

G

UDP glucuronosyltransferase family 1 member A6

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGT1A6B mRNA
Dextran Sulfate results in decreased expression of UGT1A6B mRNA

PMID:29950665 PMID:35093514

NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

UDP glucuronosyltransferase family 2 member A1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGT2A1 mRNA

NCBI chr14:20,797,262...20,825,111
Ensembl chr14:20,800,263...20,825,111

G

UDP glucuronosyltransferase family 2 member B7

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UGT2B34 mRNA

NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451

G

unc-51 like autophagy activating kinase 1

decreases phosphorylation
multiple interactions

ISO

Dextran Sulfate results in decreased phosphorylation of ULK1 protein
biochanin A inhibits the reaction [Dextran Sulfate results in decreased phosphorylation of ULK1 protein]

NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746

G

unc-80 homolog, NALCN channel complex subunit

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UNC80 mRNA

NCBI chr 9:75,461,618...75,639,849
Ensembl chr 9:75,461,599...75,639,842

G

beta-ureidopropionase 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UPB1 mRNA

NCBI chr20:13,216,693...13,243,016
Ensembl chr20:13,216,691...13,277,562

G

UPF3A, regulator of nonsense mediated mRNA decay

increases expression

ISO

Dextran Sulfate results in increased expression of UPF3A mRNA

NCBI chr16:82,459,651...82,470,686
Ensembl chr16:82,459,906...82,470,686

G

uridine phosphorylase 1

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of UPP1 protein]

NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034

G

uridine phosphorylase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of UPP2 mRNA

NCBI chr 3:63,681,671...63,726,194
Ensembl chr 3:63,681,826...63,726,191

G

ubiquinol-cytochrome c reductase, complex III subunit VII

increases expression

ISO

Dextran Sulfate results in increased expression of UQCRQ mRNA

NCBI chr10:38,086,691...38,093,871
Ensembl chr10:38,087,715...38,089,996

G

uroporphyrinogen decarboxylase

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of UROD protein]

NCBI chr 5:135,701,294...135,705,380
Ensembl chr 5:135,701,296...135,705,380

G

vav guanine nucleotide exchange factor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VAV1 mRNA

NCBI chr 9:2,248,856...2,295,905
Ensembl chr 9:2,248,914...2,296,922

G

vav guanine nucleotide exchange factor 3

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VAV3 mRNA

NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:199,700,445...200,042,343

G

vascular cell adhesion molecule 1

multiple interactions
increases expression

ISO

17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]; Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]; flavokawain B inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]; fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]; resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA]

PMID:21724996 PMID:25448682 PMID:38583725

NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801

G

versican

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VCAN mRNA

NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955

G

vinculin

decreases expression

ISO

Dextran Sulfate results in decreased expression of VCL protein

NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163

G

vitamin D receptor

multiple interactions
decreases expression

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of VDR mRNA; Cholecalciferol inhibits the reaction [Dextran Sulfate results in decreased expression of VDR protein]

PMID:29950665 PMID:38588969

NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757

G

vascular endothelial growth factor A

increases expression

ISO

Dextran Sulfate results in increased expression of VEGFA mRNA; Dextran Sulfate results in increased expression of VEGFA protein

PMID:20025956 PMID:35093514

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

vascular endothelial growth factor C

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VEGFC mRNA

NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887

G

vascular endothelial growth factor D

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VEGFD mRNA

NCBI chr X:33,704,582...33,740,305
Ensembl chr X:33,706,055...33,740,167

G

vimentin

multiple interactions
increases expression

ISO

7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of VIM protein]; [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of VIM protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of VIM mRNA

PMID:29950665 PMID:34273909 PMID:36543318

NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746

G

vasoactive intestinal peptide receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of VIPR1 mRNA

NCBI chr 8:130,181,219...130,217,098
Ensembl chr 8:130,187,731...130,217,096

G

VPS26 endosomal protein sorting factor C

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of VPS26C protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of VPS26C protein]

NCBI chr11:47,283,764...47,311,105
Ensembl chr11:47,262,071...47,311,045

G

WASP like actin nucleation promoting factor

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of WASL protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of WASL protein]

NCBI chr 4:54,049,081...54,097,653
Ensembl chr 4:54,049,082...54,097,570

G

WD repeat domain 1

decreases expression

ISO

Dextran Sulfate results in decreased expression of WDR1 protein

NCBI chr14:76,470,238...76,504,086
Ensembl chr14:76,470,176...76,504,080

G

WD repeat domain 5

multiple interactions
increases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of WDR5 protein]

NCBI chr 3:31,233,048...31,254,730
Ensembl chr 3:31,235,222...31,254,727

G

WAP four-disulfide core domain 17

increases expression

ISO

Dextran Sulfate results in increased expression of WFDC17 mRNA

NCBI chr10:69,059,451...69,060,298

G

WAP four-disulfide core domain 18

increases expression

ISO

Dextran Sulfate results in increased expression of WFDC18 mRNA

NCBI chr10:69,086,319...69,088,473
Ensembl chr10:69,086,319...69,087,172

G

Wnt inhibitory factor 1

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of WIF1 mRNA; [Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of WIF1 protein; [Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WIF1 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WIF1 mRNA]

PMID:26271895 PMID:31715269

NCBI chr 7:58,433,326...58,503,853
Ensembl chr 7:58,384,643...58,503,852

G

WNK lysine deficient protein kinase 1

multiple interactions

ISO

[Benzo(a)pyrene co-treated with Dextran Sulfate] results in increased expression of WNK1 mRNA

NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:154,800,590...154,926,147

G

WNK lysine deficient protein kinase 4

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of WNK4 mRNA

NCBI chr10:86,702,828...86,719,917
Ensembl chr10:86,702,865...86,720,198

G

Wnt family member 10A

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT10A mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT10A mRNA]

NCBI chr 9:83,798,594...83,811,060
Ensembl chr 9:83,798,594...83,811,067

G

Wnt family member 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of WNT2 mRNA

NCBI chr 4:47,294,300...47,340,284
Ensembl chr 4:47,294,300...47,421,976

G

Wnt family member 2B

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of WNT2B mRNA

NCBI chr 2:195,142,573...195,156,945
Ensembl chr 2:195,135,176...195,157,144

G

Wnt family member 3

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT3 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT3 mRNA]

NCBI chr10:89,180,224...89,224,195
Ensembl chr10:89,216,801...89,224,195

G

Wnt family member 6

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT6 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT6 mRNA]

NCBI chr 9:83,778,552...83,792,186
Ensembl chr 9:83,778,552...83,792,186

G

Wnt family member 7B

multiple interactions

ISO

[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT7B mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT7B mRNA]

NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:118,514,684...118,559,316

G

X-C motif chemokine ligand 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XCL1 mRNA

NCBI chr13:79,781,784...79,785,440
Ensembl chr13:79,781,784...79,785,440

G

X-C motif chemokine receptor 1

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XCR1 mRNA

NCBI chr 8:132,357,020...132,393,596
Ensembl chr 8:132,357,020...132,385,862

G

xanthine dehydrogenase

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of XDH protein]

NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350

G

X-linked inhibitor of apoptosis

multiple interactions

ISO

[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XIAP protein; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XIAP protein]; Camptothecin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XIAP protein]; Plant Extracts inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XIAP protein]

NCBI chr X:125,756,107...125,803,979
Ensembl chr X:125,737,971...125,803,978

G

X-prolyl aminopeptidase 1

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of XPNPEP1 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of XPNPEP1 protein]

NCBI chr 1:262,006,761...262,057,479
Ensembl chr 1:262,006,761...262,092,425

G

X-prolyl aminopeptidase 2

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XPNPEP2 mRNA

NCBI chr X:132,165,696...132,194,937
Ensembl chr X:132,165,701...132,195,126

G

Yes1 associated transcriptional regulator

multiple interactions

ISO

[RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased phosphorylation of and affects the localization of YAP1 protein

NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437

G

Y box binding protein 2

increases expression

ISO

Dextran Sulfate results in increased expression of YBX2 mRNA

NCBI chr10:55,158,420...55,164,077
Ensembl chr10:55,158,420...55,164,077

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreases expression

ISO

Dextran Sulfate results in decreased expression of YWHAE protein

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:61,106,716...61,114,291

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

decreases expression

ISO

Dextran Sulfate results in decreased expression of YWHAH protein

NCBI chr14:81,920,819...81,930,202
Ensembl chr14:81,920,590...81,947,930

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

multiple interactions

ISO

[Dextran Sulfate co-treated with bisphenol A] results in decreased expression of YWHAQ protein

NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreases expression

ISO

Dextran Sulfate results in decreased expression of YWHAZ protein

NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:69,826,404...69,849,007

G

Z-DNA binding protein 1

increases expression
multiple interactions
decreases expression

ISO

Dextran Sulfate results in increased expression of ZBP1 mRNA
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ZBP1 protein]

PMID:23894361 PMID:35362542

NCBI chr 3:182,411,665...182,427,604
Ensembl chr 3:182,411,665...182,422,839

G

zinc finger CCCH-type containing 18

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ZC3H18 protein
Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of ZC3H18 protein]

NCBI chr19:67,344,422...67,388,400
Ensembl chr19:67,343,434...67,388,399

G

zinc finger protein 422

multiple interactions
decreases expression

ISO

evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ZFP422 protein]

NCBI chr 4:151,558,254...151,565,730
Ensembl chr 4:151,556,738...151,566,152

G

zinc finger protein 821

increases expression

ISO

Dextran Sulfate results in increased expression of ZFP821 mRNA

NCBI chr19:54,589,449...54,608,341
Ensembl chr19:54,590,152...54,608,340

G

zinc finger FYVE-type containing 9

multiple interactions

ISO

[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of ZFYVE9 mRNA

NCBI chr 5:128,599,379...128,758,394
Ensembl chr 5:128,599,379...128,758,394

G

zymogen granule protein 16

decreases expression
multiple interactions

ISO

Dextran Sulfate results in decreased expression of ZG16 protein
evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ZG16 protein]

NCBI chr 1:191,088,248...191,090,605
Ensembl chr 1:191,088,248...191,090,605

G

zinc metallopeptidase STE24

increases expression
multiple interactions

ISO

Dextran Sulfate results in increased expression of ZMPSTE24 protein
evodiamine inhibits the reaction [Dextran Sulfate results in increased expression of ZMPSTE24 protein]

NCBI chr 5:139,912,395...139,945,532
Ensembl chr 5:139,913,671...139,945,532

G

zinc and ring finger 4

increases expression

ISO

Dextran Sulfate results in increased expression of ZNRF4 mRNA

NCBI chr 9:1,440,444...1,441,632
Ensembl chr 9:1,440,445...1,441,689

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

coagulation factor X

decreases activity

ISO

fondaparinux results in decreased activity of F10 protein

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

baculoviral IAP repeat-containing 2

decreases expression

ISO

fucoidan results in decreased expression of BIRC2 protein

NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911

G

baculoviral IAP repeat-containing 5

decreases expression

ISO

fucoidan results in decreased expression of BIRC5 protein

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

C-C motif chemokine ligand 5

decreases expression

ISO

fucoidan results in decreased expression of CCL5 protein

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

cyclin D2

decreases expression

ISO

fucoidan results in decreased expression of CCND2 protein

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

fucoidan results in increased expression of CDKN1A

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

gastrin

multiple interactions

EXP

fucoidan analog inhibits the reaction [Cisplatin results in decreased expression of GAST protein]

NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880

G

glutamic--pyruvic transaminase

multiple interactions

EXP

fucoidan inhibits the reaction [Aspirin results in increased expression of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

interferon gamma

multiple interactions

EXP

fucoidan promotes the reaction [Aspirin results in increased expression of IFNG protein]

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interleukin 10

multiple interactions

EXP

fucoidan promotes the reaction [Aspirin results in increased expression of IL10 protein]

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 1 beta

multiple interactions

ISO

fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

EXP

fucoidan inhibits the reaction [Aspirin results in increased expression of IL6 protein]

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases activity

ISO

fucoidan results in decreased activity of JUND protein

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148

G

matrix metallopeptidase 2

decreases secretion

ISO

fucoidan results in decreased secretion of MMP2 protein

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 3

multiple interactions

ISO

fucoidan inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826

G

matrix metallopeptidase 9

decreases expression
multiple interactions

ISO

fucoidan results in decreased expression of MMP9
wortmannin inhibits the reaction [fucoidan results in decreased expression of MMP9]

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

myeloperoxidase

multiple interactions

EXP
ISO

fucoidan inhibits the reaction [Indomethacin results in increased activity of MPO protein]

PMID:15138204 PMID:18209962

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

MYC proto-oncogene, bHLH transcription factor

decreases expression

ISO

fucoidan results in decreased expression of MYC protein

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

nuclear factor kappa B subunit 1

decreases activity

ISO

fucoidan results in decreased activity of NFKB1 protein

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

prostaglandin-endoperoxide synthase 2

multiple interactions

ISO

fucoidan inhibits the reaction [Nanotubes, Carbon inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RB transcriptional corepressor 1

decreases expression

ISO

fucoidan results in decreased expression of RB1 protein

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

REL proto-oncogene, NF-kB subunit

decreases activity

ISO

fucoidan results in decreased activity of REL protein

NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938

G

RELA proto-oncogene, NF-kB subunit

decreases activity

ISO

fucoidan results in decreased activity of RELA protein

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

TIMP metallopeptidase inhibitor 1

decreases secretion

ISO

fucoidan results in decreased secretion of TIMP1 protein

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

heparan sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

C-C motif chemokine ligand 5

multiple interactions

ISO

Heparitin Sulfate inhibits the reaction [Hydrogen Peroxide results in increased degradation of [CCL5 protein binds to CCL5 protein]]; Heparitin Sulfate inhibits the reaction [Hydrogen Peroxide results in increased degradation of CCL5 protein]

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

C-X-C motif chemokine ligand 1

multiple interactions

ISO

CXCL10 protein inhibits the reaction [CXCL1 protein binds to Heparitin Sulfate]

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

multiple interactions

ISO

CXCL10 protein inhibits the reaction [CXCL1 protein binds to Heparitin Sulfate]

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 3

multiple interactions

ISO

CXCL10 protein inhibits the reaction [CXCL1 protein binds to Heparitin Sulfate]

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

fibroblast growth factor 1

affects binding

ISO

FGF1 protein binds to Heparitin Sulfate binds to FGFR1 protein

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 10

affects activity

ISO

Heparitin Sulfate affects the activity of FGF10 protein

PMID:12781692 PMID:12818887

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibroblast growth factor 2

multiple interactions
affects binding
increases activity

ISO

Heparitin Sulfate binds to and affects the activity of FGF2 protein
Heparitin Sulfate binds to FGF2 protein
Heparitin Sulfate analog results in increased activity of FGF2 protein

PMID:12460940 PMID:15464572 PMID:15958608

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 4

affects binding

ISO

Heparitin Sulfate binds to FGF4 protein

NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085

G

fibroblast growth factor 7

affects binding

ISO

Heparitin Sulfate binds to FGF7 protein

NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328

G

fibroblast growth factor 8

affects binding
increases activity

ISO

Heparitin Sulfate binds to FGF8 protein alternative form
Heparitin Sulfate analog results in increased activity of FGF8 protein

PMID:12460940 PMID:15769253

NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605

G

Fibroblast growth factor receptor 1

affects binding
increases activity

ISO

FGF1 protein binds to Heparitin Sulfate binds to FGFR1 protein
Heparitin Sulfate analog results in increased activity of FGFR1 protein alternative form

PMID:12460940 PMID:12604602

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

fibroblast growth factor receptor 2

decreases activity

ISO

Heparitin Sulfate analog results in decreased activity of FGFR2 protein mutant form

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914

G

fibroblast growth factor receptor 3

increases activity

ISO

Heparitin Sulfate analog results in increased activity of FGFR3 protein alternative form

NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209

G

fibroblast growth factor receptor 4

affects binding

ISO

Heparitin Sulfate analog binds to FGFR4 protein

NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389

G

glucosamine (N-acetyl)-6-sulfatase

affects degradation

ISO

GNS affects the degradation of Heparitin Sulfate

NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650

G

glypican 1

affects binding
multiple interactions

ISO

GPC1 protein binds to Heparitin Sulfate
GPC1 protein modified form results in increased cleavage of [GPC1 protein binds to Heparitin Sulfate]; nitroxyl affects the reaction [GPC1 protein results in increased cleavage of [GPC1 protein binds to Heparitin Sulfate]]; Zinc affects the reaction [GPC1 protein results in increased cleavage of [GPC1 protein binds to Heparitin Sulfate]]

NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933

G

heparanase

multiple interactions
decreases abundance
affects abundance

ISO
EXP

[Heparin results in decreased activity of HPSE protein] which affects the abundance of Heparitin Sulfate; [phosphomannopentaose sulfate results in decreased activity of HPSE protein] which affects the abundance of Heparitin Sulfate
HPSE protein results in decreased abundance of Heparitin Sulfate
HPSE protein affects the abundance of Heparitin Sulfate

PMID:16899518 PMID:17121850

NCBI chr14:9,200,971...9,241,377
Ensembl chr14:9,188,275...9,241,754

G

mitogen activated protein kinase 1

multiple interactions

ISO

Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK1 protein]

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions

ISO

Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK3 protein]

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

N-deacetylase and N-sulfotransferase 1

multiple interactions

ISO

Heparitin Sulfate affects the susceptibility to [NDST1 protein co-treated with NDST2 protein]; Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK1 protein]; Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK3 protein]

NCBI chr18:56,407,308...56,470,007
Ensembl chr18:56,411,200...56,448,612

G

N-deacetylase and N-sulfotransferase 2

multiple interactions

ISO

Heparitin Sulfate affects the susceptibility to [NDST1 protein co-treated with NDST2 protein]; Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK1 protein]; Heparitin Sulfate inhibits the reaction [[NDST1 protein co-treated with NDST2 protein] affects the phosphorylation of MAPK3 protein]

NCBI chr15:3,612,775...3,623,061
Ensembl chr15:3,612,775...3,623,061

G

prion protein

affects binding

ISO

PRNP protein modified form binds to Heparitin Sulfate metabolite

NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436

G

TIMP metallopeptidase inhibitor 3

multiple interactions

ISO

[N6L peptide binds to Heparitin Sulfate] which results in increased secretion of TIMP3 protein

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

vascular endothelial growth factor A

multiple interactions

ISO

Heparitin Sulfate promotes the reaction [Dipyridamole results in increased secretion of VEGFA protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 1

affects activity
multiple interactions

ISO

Heparin affects the activity of ABCC1 protein
Heparin affects the reaction [ABCC1 protein affects the transport of Doxorubicin]

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404

G

atypical chemokine receptor 3

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ACKR3 mRNA]

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

actin alpha 2, smooth muscle

multiple interactions

EXP

Heparin analog inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

actin related protein 3

increases expression

EXP

Heparin results in increased expression of ACTR3 protein

NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ADAMTS1 mRNA]

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390

G

angiotensinogen

multiple interactions

EXP

Heparin inhibits the reaction [AGT protein affects the localization of Calcium]

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

AKT serine/threonine kinase 1

multiple interactions

EXP

Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of AKT1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

annexin A6

increases expression

EXP

Heparin results in increased expression of ANXA6 protein

NCBI chr10:39,602,106...39,657,183
Ensembl chr10:39,602,106...39,657,359

G

amyloid P component, serum

increases expression

ISO

Heparin results in increased expression of APCS protein

NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824

G

amyloid beta precursor protein

multiple interactions

ISO

Copper promotes the reaction [Heparin binds to APP protein]; Zinc promotes the reaction [Heparin binds to APP protein]

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

Rho GDP dissociation inhibitor alpha

increases expression

EXP

Heparin results in increased expression of ARHGDIA protein

NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347

G

ATPase Na+/K+ transporting subunit beta 1

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of ATP1B1 mRNA]

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

ISO

Heparin results in increased expression of BAX protein
Heparin inhibits the reaction [arsenite results in increased expression of BAX protein]

PMID:11787776 PMID:26677073

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL2, apoptosis regulator

increases expression
multiple interactions

ISO

Heparin results in increased expression of BCL2 protein
Heparin inhibits the reaction [arsenite results in decreased expression of BCL2 protein]

PMID:11787776 PMID:15205081 PMID:15671997 PMID:26677073

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

bone morphogenetic protein 6

multiple interactions
decreases expression

ISO

Heparin inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Heparin inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]
Heparin results in decreased expression of BMP6 mRNA

NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261

G

bone morphogenetic protein receptor type 1A

decreases expression

ISO

Heparin results in decreased expression of BMPR1A mRNA

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

complement C3

decreases expression

ISO

Heparin results in decreased expression of C3 protein

PMID:7948777 PMID:10568115

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C5

decreases expression

ISO

Heparin results in decreased expression of C5 protein

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

calcium voltage-gated channel subunit alpha1 E

multiple interactions

EXP

Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]

NCBI chr13:69,125,048...69,613,795
Ensembl chr13:69,132,305...69,612,983

G

capping actin protein, gelsolin like

increases expression

EXP

Heparin results in increased expression of CAPG protein

NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672

G

calpain 1

multiple interactions

ISO

Heparin inhibits the reaction [Paraoxon results in increased expression of CAPN1 protein]

NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445

G

calpain 2

multiple interactions

ISO

Heparin inhibits the reaction [Paraoxon results in increased expression of CAPN2 protein]

NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625

G

caspase 12

multiple interactions

ISO

Heparin inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP12 protein]; Heparin inhibits the reaction [Paraoxon results in increased expression of CASP12 protein]

PMID:20079824 PMID:26998625

NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442

G

caspase 3

decreases activity
multiple interactions

ISO
EXP

Heparin results in decreased activity of CASP3 protein
Heparin inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP3 protein]
Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in increased cleavage of CASP3 protein]]

PMID:16556679 PMID:26998625 PMID:30377735

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

catalase

increases activity

ISO

Heparin results in increased activity of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

C-C motif chemokine ligand 11

affects binding
multiple interactions

ISO

Heparin binds to CCL11 protein
Heparin inhibits the reaction [PLG protein affects the degradation of CCL11 protein]

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575

G

C-C motif chemokine ligand 2

decreases expression

EXP

Heparin results in decreased expression of CCL2 protein

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

CD40 ligand

decreases expression

ISO

Heparin results in decreased expression of CD40LG protein

NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475

G

cyclin-dependent kinase inhibitor 1A

increases expression

EXP

Heparin results in increased expression of CDKN1A protein

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

decreases expression
increases expression

ISO

Heparin analog results in decreased expression of CDKN1B protein
Heparin analog results in increased expression of CDKN1B protein

PMID:18057711 PMID:20201787

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

collagen type XVIII alpha 1 chain

affects binding

ISO

Heparin binds to COL18A1 protein alternative form

NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112

G

C-reactive protein

increases expression

ISO

Heparin results in increased expression of CRP protein

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

colony stimulating factor 3

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA]

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860

G

catenin beta 1

multiple interactions

EXP

Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]; Lithium Chloride inhibits the reaction [Heparin promotes the reaction [Doxorubicin results in decreased expression of CTNNB1 protein]]

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

C-X-C motif chemokine ligand 10

multiple interactions

EXP

Heparin inhibits the reaction [endotoxin, Escherichia coli results in increased expression of CXCL10 mRNA]

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 12

decreases expression

ISO

Heparin analog results in decreased expression of CXCL12 mRNA; Heparin analog results in decreased expression of CXCL12 protein

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 2

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CXCL2 mRNA]; Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CXCL2 protein]]

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine receptor 4

decreases expression

ISO

Heparin analog results in decreased expression of CXCR4 mRNA; Heparin analog results in decreased expression of CXCR4 protein

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459

G

DDAH family member 2, ADMA-independent

decreases expression

EXP

Heparin results in decreased expression of DDAH2 protein

NCBI chr20:3,766,115...3,769,161
Ensembl chr20:3,766,120...3,769,183

G

desmin

decreases expression

EXP

Heparin results in decreased expression of DES protein

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347

G

E2F transcription factor 1

decreases expression

ISO

Heparin analog results in decreased expression of E2F1 protein

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

endothelin 1

multiple interactions
decreases expression
decreases secretion

ISO
EXP

Heparin inhibits the reaction [F2 protein results in increased expression of EDN1 mRNA]; Heparin inhibits the reaction [F2 protein results in increased secretion of EDN1 protein]
Heparin results in decreased expression of EDN1 mRNA
Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Inositol 1,4,5-Trisphosphate]
Heparin results in decreased secretion of EDN1 protein

PMID:1443220 PMID:7509996 PMID:8408661

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

epidermal growth factor

decreases activity

ISO

Heparin results in decreased activity of EGF protein

NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297

G

epidermal growth factor receptor

decreases expression
increases phosphorylation

ISO

Heparin results in decreased expression of EGFR mRNA; Heparin results in decreased expression of EGFR protein
Heparin results in increased phosphorylation of EGFR protein

PMID:16475731 PMID:16556679

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

egl-9 family hypoxia-inducible factor 3

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGLN3 mRNA]

NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015

G

coagulation factor X

decreases activity

ISO
EXP

Heparin results in decreased activity of F10 protein

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

G

coagulation factor II, thrombin

multiple interactions
decreases expression
increases expression

ISO

F2 protein promotes the reaction [Heparin results in increased abundance of Nitric Oxide]; Heparin deficiency results in increased cleavage of and results in increased activity of F2 protein; Heparin deficiency results in increased expression of [SERPINC1 protein binds to F2 protein]; Heparin inhibits the reaction [F2 protein affects the localization of SELP protein]; Heparin inhibits the reaction [F2 protein results in increased cleavage of F2R protein]; Heparin inhibits the reaction [F2 protein results in increased expression of EDN1 mRNA]; Heparin inhibits the reaction [F2 protein results in increased secretion of EDN1 protein]
Heparin results in increased expression of [F2 protein binds to SERPINC1 protein]
Heparin results in decreased expression of F2 protein
Heparin deficiency results in increased expression of F2 protein; Heparin results in increased expression of F2 protein

PMID:7509996 PMID:7895349 PMID:8408661 PMID:9740346 PMID:11869846 More...

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246

G

coagulation factor II (thrombin) receptor

multiple interactions

ISO

Heparin inhibits the reaction [F2 protein results in increased cleavage of F2R protein]

NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579

G

Fas cell surface death receptor

increases expression

ISO

Heparin results in increased expression of FAS protein

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

Fc gamma receptor 2A

affects binding

ISO

[Heparin binds to PF4 protein] which binds to FCGR2A protein

NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394

G

fibrinogen alpha chain

increases cleavage

ISO

Heparin deficiency results in increased cleavage of FGA protein

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

fibroblast growth factor 1

multiple interactions
affects binding

ISO
EXP

[Heparin analog binds to FGFR2 protein alternative form] which binds to and results in increased activity of FGF1 protein; Heparin analog promotes the reaction [FGF1 protein binds to FGF1 protein]
[Heparin binds to FGFR2 protein alternative form] which binds to FGF1 protein
Heparin affects the reaction [FGF1 protein binds to FGFR4 protein]; Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of AKT1 protein]; Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K1 protein]; Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K2 protein]; Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAPK1 protein]; Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAPK3 protein]; Heparin promotes the reaction [FGF1 protein results in increased expression of FGF1 protein]
Heparin promotes the reaction [FGFR1 protein binds to FGF1 protein]; Heparin promotes the reaction [FGFR3 protein binds to FGF1 protein]

PMID:1379594 PMID:8576258 PMID:10336501 PMID:10860838 PMID:14966081 More...

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 10

multiple interactions

ISO

Heparin promotes the reaction [FGF10 protein binds to FGFR2 protein]

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibroblast growth factor 19

affects binding
multiple interactions

ISO

Heparin binds to FGF19 protein
Heparin promotes the reaction [FGF19 protein binds to FGFR4 protein]

PMID:10525310 PMID:14730967

NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267

G

fibroblast growth factor 2

affects binding
decreases expression
multiple interactions
affects activity

ISO
EXP

Heparin binds to FGF2 protein; Heparin binds to FGFR1 protein binds to FGF2 protein
Heparin results in decreased expression of FGF2 protein
[Heparin binds to FGFR2 protein alternative form] which binds to FGF2 protein
Heparin affects the reaction [FGF2 protein binds to FGFR4 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of AKT1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K2 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]
Heparin affects the activity of FGF2 protein
Heparin promotes the reaction [FGFR1 protein binds to FGF2 protein]; Heparin promotes the reaction [FGFR2 protein binds to FGF2 protein]

PMID:1373495 PMID:1379594 PMID:8441232 PMID:10336501 PMID:10860838 More...

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 23

increases activity

ISO

Heparin analog results in increased activity of FGF23 protein

NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991

G

fibroblast growth factor 3

affects activity

ISO

Heparin affects the activity of FGF3 protein

NCBI chr 1:209,430,457...209,434,832
Ensembl chr 1:209,430,457...209,434,832

G

fibroblast growth factor 4

multiple interactions

ISO

Heparin binds to and results in increased activity of FGF4 protein

NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085

G

fibroblast growth factor 5

affects activity

ISO

Heparin affects the activity of FGF5 protein

NCBI chr14:11,627,906...11,650,243
Ensembl chr14:11,627,906...11,650,243

G

fibroblast growth factor 7

affects binding

EXP

[Heparin binds to FGFR2 protein alternative form] which binds to FGF7 protein

NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328

G

Fibroblast growth factor receptor 1

affects binding
multiple interactions

ISO

Heparin binds to FGFR1 protein binds to FGF2 protein
Heparin promotes the reaction [FGFR1 protein binds to FGF1 protein]; Heparin promotes the reaction [FGFR1 protein binds to FGF2 protein]

PMID:1379594 PMID:15096041

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

fibroblast growth factor receptor 2

multiple interactions
affects binding
affects activity

ISO
EXP

[Heparin analog binds to FGFR2 protein alternative form] which binds to and results in increased activity of FGF1 protein; Heparin promotes the reaction [FGF10 protein binds to FGFR2 protein]
[Heparin binds to FGFR2 protein alternative form] which binds to FGF1 protein; [Heparin binds to FGFR2 protein alternative form] which binds to FGF2 protein; [Heparin binds to FGFR2 protein alternative form] which binds to FGF7 protein
Heparin promotes the reaction [FGFR2 protein binds to FGF2 protein]
Heparin affects the activity of FGFR2 protein

PMID:1373495 PMID:10860838 PMID:15632068 PMID:16219767

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914

G

fibroblast growth factor receptor 3

affects activity
multiple interactions

ISO

Heparin affects the activity of FGFR3 protein
Heparin promotes the reaction [FGFR3 protein binds to FGF1 protein]

NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209

G

fibroblast growth factor receptor 4

affects binding
multiple interactions

ISO
EXP

Heparin analog binds to FGFR4 protein
Heparin affects the reaction [FGF1 protein binds to FGFR4 protein]; Heparin affects the reaction [FGF2 protein binds to FGFR4 protein]
Heparin promotes the reaction [FGF19 protein binds to FGFR4 protein]; Heparin promotes the reaction [FGFR4 protein binds to FGFR4 protein]

PMID:10336501 PMID:10525310 PMID:10736564 PMID:11278860

NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
decreases expression
multiple interactions

ISO
EXP

Heparin results in increased expression of FOS protein
Heparin results in decreased expression of FOS mRNA
Heparin inhibits the reaction [4-O-methyl-12-O-tetradecanoylphorbol 13-acetate results in increased expression of FOS mRNA]

PMID:2099192 PMID:9083085

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

GATA binding protein 4

multiple interactions

EXP

Heparin inhibits the reaction [Inositol 1,4,5-Trisphosphate results in increased expression of GATA4 protein]

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609

G

glucosamine (N-acetyl)-6-sulfatase

affects degradation

ISO

GNS affects the degradation of Heparin

NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650

G

glutamic--pyruvic transaminase

multiple interactions

EXP

Heparin inhibits the reaction [Diclofenac promotes the reaction [endotoxin, Escherichia coli results in increased activity of GPT protein]]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

granzyme B

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of GZMB mRNA]

NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469

G

hepcidin antimicrobial peptide

decreases expression
decreases secretion
multiple interactions

ISO

Heparin results in decreased expression of HAMP mRNA
Heparin results in decreased secretion of HAMP protein modified form
Heparin inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Heparin inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Heparin inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]

PMID:25633564 PMID:25686467

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297

G

hepatocyte growth factor

multiple interactions
affects binding
increases expression

ISO

Heparin promotes the reaction [HGF protein binds to and results in increased activity of MET protein]
HGF protein binds to Heparin
Heparin results in increased expression of HGF protein

PMID:9083085 PMID:18243369

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

heme oxygenase 1

multiple interactions

EXP

Heparin inhibits the reaction [endotoxin, Escherichia coli results in increased expression of HMOX1 mRNA]

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heparanase

multiple interactions

ISO

[Heparin results in decreased activity of HPSE protein] which affects the abundance of Heparitin Sulfate

NCBI chr14:9,200,971...9,241,377
Ensembl chr14:9,188,275...9,241,754

G

histidine-rich glycoprotein

multiple interactions

ISO

Heparin inhibits the reaction [Zinc results in increased activity of HRG protein]

NCBI chr11:91,559,087...91,573,982
Ensembl chr11:91,559,091...91,573,982

G

immunoglobulin superfamily, member 10

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IGSF10 mRNA]

NCBI chr 2:145,725,868...145,754,850
Ensembl chr 2:145,725,878...145,754,579

G

interleukin 6

increases expression
increases secretion
multiple interactions

ISO
EXP

Heparin results in increased expression of IL6 protein
Heparin analog results in increased secretion of IL6 protein
Heparin inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of IL6 mRNA]

PMID:16391376 PMID:16401727 PMID:25633564 PMID:26476401

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

integrin subunit alpha M

decreases expression
increases expression

ISO

Heparin results in decreased expression of ITGAM protein
Heparin results in increased expression of ITGAM protein

PMID:8595612 PMID:8993250

NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943

G

integrin subunit alpha X

decreases expression

ISO

Heparin results in decreased expression of ITGAX protein

NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:192,149,905...192,171,151

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

ISO

Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

KLF transcription factor 4

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of KLF4 mRNA]

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592

G

keratin 18

increases expression

ISO

Heparin results in increased expression of KRT18 protein

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

lactate dehydrogenase B

decreases expression

EXP

Heparin results in decreased expression of LDHB protein

NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408

G

lipoprotein lipase

multiple interactions

EXP
ISO

[etofibrate co-treated with Heparin] results in increased secretion of LPL protein
Heparin results in increased expression of and results in increased activity of LPL protein

PMID:2313202 PMID:3179329

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107

G

mitogen activated protein kinase kinase 1

multiple interactions

EXP

Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K1 protein]

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184

G

mitogen activated protein kinase kinase 2

multiple interactions

EXP

Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAP2K2 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAP2K2 protein]

NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940

G

mitogen activated protein kinase 1

multiple interactions
increases activity

ISO
EXP

Heparin analog inhibits the reaction [Glucose results in increased phosphorylation of MAPK1 protein]
Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK1 protein]
Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAPK1 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK1 protein]
Heparin results in increased activity of MAPK1 protein

PMID:14966081 PMID:16556679 PMID:18057711 PMID:19937756

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

multiple interactions
increases activity

ISO
EXP

Heparin analog inhibits the reaction [Glucose results in increased phosphorylation of MAPK3 protein]
Heparin inhibits the reaction [sodium chlorate results in decreased phosphorylation of MAPK3 protein]
Heparin inhibits the reaction [FGF1 protein results in increased phosphorylation of MAPK3 protein]; Heparin inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK3 protein]
Heparin results in increased activity of MAPK3 protein

PMID:14966081 PMID:16556679 PMID:18057711 PMID:19937756

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

microtubule-associated protein tau

multiple interactions

ISO

Heparin promotes the reaction [MAPT protein binds to MAPT protein]; Mercuric Chloride promotes the reaction [Heparin promotes the reaction [MAPT protein binds to MAPT protein]]

PMID:20665688 PMID:31678113

NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108

G

mast cell protease 4

increases activity

EXP

Heparin increases activity of Mcpt4 protein

RGD

NCBI chr15:33,471,491...33,474,112
Ensembl chr15:33,471,491...33,474,110

G

MET proto-oncogene, receptor tyrosine kinase

multiple interactions

ISO

Heparin promotes the reaction [HGF protein binds to and results in increased activity of MET protein]

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

macrophage migration inhibitory factor

affects binding

ISO

MIF protein binds to Heparin

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

matrix metallopeptidase 1

decreases activity

ISO

Heparin results in decreased activity of MMP1 protein

NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964

G

matrix metallopeptidase 14

decreases expression

ISO

Heparin analog results in decreased expression of MMP14 mRNA

NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893

G

matrix metallopeptidase 2

decreases activity

ISO

Heparin results in decreased activity of MMP2 protein

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 9

decreases activity
increases expression
multiple interactions

ISO

Heparin results in decreased activity of MMP9 protein
Heparin results in increased expression of MMP9 mRNA; Heparin results in increased expression of MMP9 protein
Heparin results in increased metabolism of and results in increased activity of MMP9 protein

PMID:10958381 PMID:14630814 PMID:16190367

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

myeloperoxidase

multiple interactions

ISO

Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

moesin

increases expression

EXP

Heparin results in increased expression of MSN protein

NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129

G

MYC proto-oncogene, bHLH transcription factor

increases expression
decreases expression

ISO
EXP

Heparin results in increased expression of MYC protein
Heparin results in decreased expression of MYC mRNA

PMID:2099192 PMID:11787776 PMID:16475731

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

nuclear factor of activated T-cells 3

multiple interactions

EXP

Heparin inhibits the reaction [Inositol 1,4,5-Trisphosphate results in increased expression of NFATC3 protein]

NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992

G

NFE2 like bZIP transcription factor 2

increases expression

ISO

Heparin analog results in increased expression of NFE2L2 mRNA

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

Parkinsonism associated deglycase

increases expression

EXP

Heparin results in increased expression of PARK7 protein

NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825

G

poly (ADP-ribose) polymerase 1

multiple interactions

EXP

Heparin promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

platelet derived growth factor subunit B

affects expression

EXP

Heparin affects the expression of PDGFB protein

NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343

G

platelet derived growth factor receptor alpha

decreases expression

ISO

Heparin results in decreased expression of PDGFRA mRNA

NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516

G

pyruvate dehydrogenase E1 subunit beta

decreases expression

EXP

Heparin results in decreased expression of PDHB protein

NCBI chr15:19,182,789...19,188,731
Ensembl chr15:19,181,208...19,188,976

G

platelet factor 4

affects binding
increases secretion

ISO

[Heparin binds to PF4 protein] which binds to FCGR2A protein; Heparin binds to PF4 protein
Heparin results in increased secretion of PF4 protein

PMID:2437338 PMID:2709525 PMID:8282825 PMID:20162249

NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392

G

phosphatidylinositol transfer protein, alpha

increases expression

EXP

Heparin results in increased expression of PITPNA protein

NCBI chr10:60,929,050...60,969,614
Ensembl chr10:60,929,007...60,971,830

G

plasminogen activator, tissue type

increases expression

ISO

Heparin results in increased expression of PLAT mRNA; Heparin results in increased expression of PLAT protein

PMID:14630814 PMID:16190367

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696

G

plasminogen activator, urokinase

decreases expression

ISO

Heparin analog results in decreased expression of PLAU mRNA

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030

G

plasminogen

multiple interactions

ISO

Heparin inhibits the reaction [PLG protein affects the degradation of CCL11 protein]

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

pro-platelet basic protein

increases secretion

ISO

Heparin results in increased secretion of PPBP protein

NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299

G

protein C, inactivator of coagulation factors Va and VIIIa

increases activity

ISO

Heparin deficiency results in increased activity of PROC protein

NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964

G

proteasome 20S subunit beta 5

decreases activity
decreases expression

ISO

Heparin analog results in decreased activity of PSMB5 protein
Heparin analog results in decreased expression of PSMB5 mRNA

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 20S subunit beta 6

decreases expression

ISO

Heparin analog results in decreased expression of PSMB6 mRNA

NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,737,888...55,740,218

G

proteasome 20S subunit beta 7

decreases expression

ISO

Heparin analog results in decreased expression of PSMB7 mRNA

NCBI chr 3:42,767,500...42,827,470
Ensembl chr 3:42,767,501...42,827,601

G

proteasome activator subunit 1

increases expression

EXP

Heparin results in increased expression of PSME1 protein

NCBI chr15:33,038,962...33,041,849
Ensembl chr15:33,038,597...33,041,848

G

prostaglandin-endoperoxide synthase 2

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of PTGS2 mRNA]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

protein tyrosine kinase 2

decreases phosphorylation

ISO

Heparin results in decreased phosphorylation of PTK2 protein

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091

G

paxillin

decreases phosphorylation

ISO

Heparin results in decreased phosphorylation of PXN protein

NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697

G

Rac family small GTPase 1

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of RAC1 mRNA]

NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109

G

RB transcriptional corepressor 1

multiple interactions

ISO

Heparin analog results in decreased expression of and results in decreased phosphorylation of RB1 protein

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

Heparin inhibits the reaction [arsenite affects the localization of RELA protein]; Heparin inhibits the reaction [TNF protein affects the localization of RELA protein]

PMID:10843908 PMID:26677073

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

S100 calcium binding protein A1

affects expression

EXP

Heparin affects the expression of S100A1 protein

NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:178,291,503...178,296,346

G

S100 calcium binding protein A6

affects expression
increases expression

EXP

Heparin affects the expression of S100A6 protein
Heparin results in increased expression of S100A6 protein

PMID:12186470 PMID:17488504

NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762

G

S100 calcium binding protein B

affects expression

EXP

Heparin affects the expression of S100B protein

NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081

G

syndecan 1

decreases expression

ISO

Heparin analog results in decreased expression of SDC1 mRNA

NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500

G

syndecan 2

decreases expression

ISO

Heparin analog results in decreased expression of SDC2 mRNA

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294

G

syndecan 4

increases expression

ISO

Heparin analog results in increased expression of SDC4 mRNA

NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670

G

selectin L

decreases expression
increases expression

ISO

Heparin results in decreased expression of SELL protein
Heparin results in increased expression of SELL protein

PMID:8595612 PMID:8993250

NCBI chr13:78,950,100...78,969,604
Ensembl chr13:78,950,015...78,969,600

G

selectin P

multiple interactions
increases expression

ISO

Heparin inhibits the reaction [F2 protein affects the localization of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]
Heparin results in increased expression of SELP protein

PMID:9740346 PMID:10544909

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:79,009,475...79,044,987

G

septin 2

increases expression

EXP

Heparin results in increased expression of SEPTIN2 protein

NCBI chr 9:101,465,535...101,498,766
Ensembl chr 9:101,465,650...101,498,759

G

serpin family C member 1

decreases expression
multiple interactions

ISO

Heparin deficiency results in decreased expression of SERPINC1 protein; Heparin results in decreased expression of SERPINC1 protein
Heparin results in increased expression of [F2 protein binds to SERPINC1 protein]
Heparin deficiency results in increased expression of [SERPINC1 protein binds to F2 protein]

PMID:73932 PMID:7895349 PMID:8122184 PMID:11869846 PMID:16961586

NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643

G

serpin family E member 1

multiple interactions

EXP

Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]]; Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein]

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

secreted frizzled-related protein 1

multiple interactions

EXP

Heparin promotes the reaction [Doxorubicin results in increased secretion of SFRP1 protein]

NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736

G

solute carrier family 5 member 3

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLC5A3 mRNA]

NCBI chr11:44,799,787...44,802,233
Ensembl chr11:44,790,297...44,818,157

G

STE20-like kinase

multiple interactions

EXP

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SLK mRNA]

NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829

G

stress-induced phosphoprotein 1

increases expression

EXP

Heparin results in increased expression of STIP1 protein

NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654

G

transgelin 2

decreases expression

EXP

Heparin results in decreased expression of TAGLN2 protein

NCBI chr13:87,499,350...87,506,328
Ensembl chr13:87,499,394...87,506,330

G

transferrin receptor

multiple interactions
decreases expression

EXP
ISO

Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of TFRC mRNA]
Heparin results in decreased expression of TFRC protein

PMID:16401727 PMID:25633564

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta 1

decreases expression

EXP

Heparin results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

tumor necrosis factor

multiple interactions
increases expression

ISO

Heparin inhibits the reaction [TNF protein affects the localization of RELA protein]
Heparin results in increased expression of TNF protein

PMID:10843908 PMID:17162433

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

tumor protein p53

decreases expression

ISO

Heparin analog results in decreased expression of TP53 protein

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

vascular endothelial growth factor A

affects binding

ISO

Heparin binds to VEGFA protein alternative form

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

keratan sulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

increases chemical synthesis

ISO

B3GNT2 protein results in increased chemical synthesis of Keratan Sulfate

NCBI chr14:101,009,682...101,034,507
Ensembl chr14:100,967,131...101,043,412

G

beta-1,4-galactosyltransferase 1

increases chemical synthesis

ISO

B4GALT1 protein results in increased chemical synthesis of Keratan Sulfate

NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445

G

carbohydrate sulfotransferase 6

multiple interactions

ISO

CHST6 protein results in increased sulfation of and results in increased chemical synthesis of Keratan Sulfate
CHST5 protein results in increased sulfation of and results in increased chemical synthesis of Keratan Sulfate

NCBI chr19:39,860,729...39,881,019
Ensembl chr19:56,769,967...56,790,306

G

glucosamine (N-acetyl)-6-sulfatase

affects degradation

ISO

GNS affects the degradation of Keratan Sulfate

NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

multiple interactions

ISO

laurolactam binds to and results in decreased activity of AR protein

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

estrogen receptor 1

multiple interactions

ISO

laurolactam binds to and results in decreased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

nuclear receptor subfamily 3, group C, member 1

multiple interactions

ISO

laurolactam binds to and results in decreased activity of NR3C1 protein

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843

G

progesterone receptor

multiple interactions

ISO

laurolactam binds to and results in decreased activity of PGR protein

NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

intercellular adhesion molecule 1

multiple interactions

ISO

mycotrienin I inhibits the reaction [TNF protein results in increased expression of and affects the localization of ICAM1 protein]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

tumor necrosis factor

multiple interactions

ISO

mycotrienin I inhibits the reaction [TNF protein results in increased expression of and affects the localization of ICAM1 protein]

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

sucrose octasulfate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

fibroblast growth factor receptor 2

affects binding

ISO

sucrose octasulfate binds to FGFR2 protein

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

nucleotide-binding oligomerization domain containing 2

affects binding
multiple interactions

ISO

NOD2 protein binds to sulfolipid I
sulfolipid I inhibits the reaction [NOD2 protein binds to Sulfoglycosphingolipids]

NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	20862
role	20820
chemical role	20396
catalyst	8410
sulfuric acid	8360
sulfuric acid derivative	8360
organic sulfate	2483
carbohydrate sulfate	1959
(2R,3R,4R)-2-[(2R,3S,4R,5R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2R,3R,4R)-2-[(2R,3S,4R,5R,6S)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2R,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R,6S)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3R,4R)-2-[(2R,3S,4R,5R,6R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2S,3R,4R)-2-[(2R,3S,4R,5R,6R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R,6S)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3S,4S,5R,6R)-6-[(2R,3S,4R,5R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid	0
2-O-sulfo-alpha-L-idopyranuronic acid +	0
5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid	0
GlyTouCan G00058XR	0
GlyTouCan G00232ED	0
GlyTouCan G01155JM	0
GlyTouCan G01664MY	0
GlyTouCan G02820IE	0
\{[3,4-dihydroxy-5-(hydroxymethyl)-2-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}oxolan-2-yl]methoxy\}sulfonic acid	0
\{[3,4-dihydroxy-5-(hydroxymethyl)-5-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}oxolan-2-yl]methoxy\}sulfonic acid	0
glycerone sulfate	0
monosaccharide sulfate +	24
nucleotide-sugar sulfate +	0
oligosaccharide sulfate +	2
polysaccharide sulfate +	1858
sulfated glycosaminoglycan +	191
sulfoglycolipid +	1
Path 2
Term	Annotations
CHEBI ontology	20862
subatomic particle	20860
composite particle	20860
hadron	20860
baryon	20860
nucleon	20860
atomic nucleus	20860
atom	20860
main group element atom	20781
p-block element atom	20781
chalcogen	20491
oxygen atom	20457
oxygen molecular entity	20457
hydroxides	20230
oxoacid	19289
chalcogen oxoacid	13891
sulfur oxoacid	13683
sulfuric acid	8360
sulfuric acid derivative	8360
sulfates	8355
organic sulfate	2483
carbohydrate sulfate	1959
(2R,3R,4R)-2-[(2R,3S,4R,5R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2R,3R,4R)-2-[(2R,3S,4R,5R,6S)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2R,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R,6S)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3R,4R)-2-[(2R,3S,4R,5R,6R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2S,3R,4R)-2-[(2R,3S,4R,5R,6R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-3-sulfooxy-3,4-dihydro-2H-pyran-6-carboxylic acid	0
(2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-[(2R,3R,4R,5R,6S)-6-hydroxy-5-(sulfoamino)-4-sulfooxy-2-(sulfooxymethyl)oxan-3-yl]oxyoxane-2-carboxylic acid	0
(2S,3S,4S,5R,6R)-6-[(2R,3S,4R,5R)-4,6-Dihydroxy-5-(sulfoamino)-2-(sulfooxymethyl)oxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid	0
2-O-sulfo-alpha-L-idopyranuronic acid +	0
5-dehydro-4-deoxy-2-O-sulfo-D-glucuronic acid	0
GlyTouCan G00058XR	0
GlyTouCan G00232ED	0
GlyTouCan G01155JM	0
GlyTouCan G01664MY	0
GlyTouCan G02820IE	0
\{[3,4-dihydroxy-5-(hydroxymethyl)-2-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}oxolan-2-yl]methoxy\}sulfonic acid	0
\{[3,4-dihydroxy-5-(hydroxymethyl)-5-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}oxolan-2-yl]methoxy\}sulfonic acid	0
glycerone sulfate	0
monosaccharide sulfate +	24
nucleotide-sugar sulfate +	0
oligosaccharide sulfate +	2
polysaccharide sulfate +	1858
sulfated glycosaminoglycan +	191
sulfoglycolipid +	1

paths to the root