mancude ring - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	mancude ring	go back to main search page
Accession:	CHEBI:35568	browse the term
Definition:	Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds.
Synonyms:	related_synonym:	mancude rings; mancude-ring systems; mancunide-ring systems

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Rat (4044 ) Mouse (3902 ) Human (3868 ) Chinchilla (0 ) Bonobo (0 ) Dog (0 ) Squirrel (0 ) Pig (2 ) Green Monkey (0) Naked Mole-rat (0 ) All
Genes (4044)

1,10-phenanthroline

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

decreases expression

ISO

1,10-phenanthroline results in decreased expression of ACE mRNA

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

aryl hydrocarbon receptor

decreases activity
multiple interactions

EXP
ISO

1,10-phenanthroline results in decreased activity of AHR protein
1,10-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; 1,10-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Zinc inhibits the reaction [1,10-phenanthroline results in decreased activity of AHR protein]
[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein; resveratrol inhibits the reaction [[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased activity of AHR protein]

PMID:1322109 PMID:2160969 PMID:27180721

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

adenylate kinase 1

decreases expression

ISO

1,10-phenanthroline results in decreased expression of AK1 mRNA

NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757

G

A-kinase anchoring protein 9

increases expression

ISO

1,10-phenanthroline results in increased expression of AKAP9 mRNA

NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338

G

aldo-keto reductase family 1, member C1

decreases activity

ISO

1,10-phenanthroline results in decreased activity of AKR1C1 protein

PMID:8573067 PMID:12604236

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

aldo-keto reductase family 1, member C2

decreases activity

ISO

1,10-phenanthroline results in decreased activity of AKR1C2 protein

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686

G

aldo-keto reductase family 1, member C3

decreases activity

ISO

1,10-phenanthroline results in decreased activity of AKR1C3 protein

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

aldolase, fructose-bisphosphate A

increases expression

ISO

1,10-phenanthroline results in increased expression of ALDOA mRNA

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

aldolase, fructose-bisphosphate C

increases expression

ISO

1,10-phenanthroline results in increased expression of ALDOC mRNA

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133

G

ankyrin repeat domain 37

increases expression

ISO

1,10-phenanthroline results in increased expression of ANKRD37 mRNA

NCBI chr16:53,001,487...53,004,545
Ensembl chr16:52,994,740...53,004,545

G

alanyl aminopeptidase, membrane

decreases activity
multiple interactions

ISO

1,10-phenanthroline results in decreased activity of ANPEP protein
Edetic Acid promotes the reaction [1,10-phenanthroline results in decreased activity of ANPEP protein]

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

aquaporin 3 (Gill blood group)

decreases expression

ISO

1,10-phenanthroline results in decreased expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685

G

aspartoacylase

decreases activity

ISO

1,10-phenanthroline results in decreased activity of ASPA protein

NCBI chr10:58,390,204...58,443,790
Ensembl chr10:58,379,410...58,443,769

G

activating transcription factor 6

multiple interactions

ISO

[1,10-phenanthroline results in decreased activity of MBTPS2 protein] which affects the localization of ATF6 protein; [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which results in decreased cleavage of ATF6 protein

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

BCL2 interacting protein 3 like

decreases expression

ISO

1,10-phenanthroline results in decreased expression of BNIP3L mRNA

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282

G

carbonic anhydrase 9

increases expression

ISO

1,10-phenanthroline results in increased expression of CA9 mRNA

NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626

G

catalase

decreases expression

ISO

1,10-phenanthroline results in decreased expression of CAT mRNA

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

CD83 molecule

increases expression

ISO

1,10-phenanthroline results in increased expression of CD83 mRNA

NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047

G

CD86 molecule

increases expression
multiple interactions

ISO

1,10-phenanthroline results in increased expression of CD86 mRNA
Acetylcysteine inhibits the reaction [1,10-phenanthroline results in increased expression of CD86 mRNA]; SB 203580 inhibits the reaction [1,10-phenanthroline results in increased expression of CD86 mRNA]

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361

G

CF transmembrane conductance regulator

increases activity

ISO

1,10-phenanthroline results in increased activity of CFTR protein

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases stability

ISO
EXP

1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; [1,10-phenanthroline co-treated with cupric chloride] inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; ferric chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; zinc chloride inhibits the reaction [1,10-phenanthroline inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]
1,10-phenanthroline results in increased stability of CYP1A1 mRNA
1,10-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]
[copper(II) nitrate binds to 1,10-phenanthroline binds to Quinolones] which results in increased expression of CYP1A1 mRNA

PMID:1322109 PMID:19896525 PMID:27180721

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

egl-9 family hypoxia-inducible factor 1

increases expression

ISO

1,10-phenanthroline results in increased expression of EGLN1 mRNA

NCBI chr19:69,765,276...69,804,681

G

egl-9 family hypoxia-inducible factor 2

decreases expression

ISO

1,10-phenanthroline results in decreased expression of EGLN2 mRNA

NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:91,579,206...91,587,385

G

early growth response 1

increases expression

ISO

1,10-phenanthroline results in increased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

enolase 1

increases expression

ISO

1,10-phenanthroline results in increased expression of ENO1 mRNA

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

enolase 2

increases expression

ISO

1,10-phenanthroline results in increased expression of ENO2 mRNA

NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220

G

ERCC excision repair 2, TFIIH core complex helicase subunit

decreases expression

ISO

1,10-phenanthroline results in decreased expression of ERCC2 mRNA

NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:88,160,988...88,175,102

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

ISO

1,10-phenanthroline results in increased expression of GAPDH mRNA

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377

G

glutathione peroxidase 3

decreases expression

ISO

1,10-phenanthroline results in decreased expression of GPX3 mRNA

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405

G

H2A.X variant histone

multiple interactions

ISO

[Copper binds to phthalic acid binds to 1,10-phenanthroline] which results in increased expression of H2AX protein modified form

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

hepcidin antimicrobial peptide

decreases expression

ISO

1,10-phenanthroline results in decreased expression of HAMP mRNA

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297

G

heparin-binding EGF-like growth factor

increases expression

ISO

1,10-phenanthroline results in increased expression of HBEGF mRNA

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

hypoxia inducible factor 1 subunit alpha

multiple interactions
increases activity

ISO

4'-O-methylalpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]; alpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]
1,10-phenanthroline results in increased activity of HIF1A protein
HIF1A protein promotes the reaction [1,10-phenanthroline results in increased expression of VEGFA protein]

PMID:19091749 PMID:19502547

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

hypoxia inducible factor 3 subunit alpha

decreases expression

ISO

1,10-phenanthroline results in decreased expression of HIF3A mRNA

NCBI chr 1:86,846,196...86,878,527
Ensembl chr 1:86,850,554...86,877,838

G

hypoxia inducible lipid droplet-associated

increases expression

ISO

1,10-phenanthroline results in increased expression of HILPDA mRNA

NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423

G

hexokinase 1

increases expression

ISO

1,10-phenanthroline results in increased expression of HK1 mRNA

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

hexokinase 2

increases expression

ISO

1,10-phenanthroline results in increased expression of HK2 mRNA

NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275

G

heme oxygenase 1

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of HMOX1 protein]; 1,10-phenanthroline inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; 1,10-phenanthroline inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; 1,10-phenanthroline inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; 1,10-phenanthroline inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; 1,10-phenanthroline inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]

PMID:9747510 PMID:15629867 PMID:20888885

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

intercellular adhesion molecule 1

multiple interactions

ISO

1,10-phenanthroline affects the reaction [Smoke results in increased expression of ICAM1 protein]

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

insulin-like growth factor binding protein 5

decreases degradation

EXP

1,10-phenanthroline results in decreased degradation of IGFBP5 protein

NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390

G

interleukin 1 receptor type 1

decreases expression

ISO

1,10-phenanthroline results in decreased expression of IL1R1 mRNA

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579

G

laminin subunit gamma 2

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [Mustard Gas results in increased degradation of LAMC2 protein]

NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102

G

lactate dehydrogenase A

increases expression

ISO

1,10-phenanthroline results in increased expression of LDHA mRNA

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

membrane-bound transcription factor peptidase, site 2

multiple interactions

ISO

[1,10-phenanthroline results in decreased activity of MBTPS2 protein] which affects the localization of ATF6 protein; [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which affects the localization of SREBF1 protein; [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which results in decreased cleavage of ATF6 protein; [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which results in decreased cleavage of SREBF1 protein

NCBI chr X:41,225,956...41,290,030
Ensembl chr X:41,254,335...41,277,701

G

MDM2 proto-oncogene

increases expression

ISO

1,10-phenanthroline results in increased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

macrophage migration inhibitory factor

increases expression

ISO

1,10-phenanthroline results in increased expression of MIF mRNA

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

matrix metallopeptidase 8

decreases activity

ISO

1,10-phenanthroline results in decreased activity of MMP8 protein

NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729

G

matrix metallopeptidase 9

multiple interactions

ISO
EXP

1,10-phenanthroline inhibits the reaction [PLAU protein results in increased activity of MMP9 protein]
1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein]

PMID:20177776 PMID:20195827

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

neurolysin

decreases activity

EXP

1,10-phenanthroline decreases activity of Nln protein

RGD

NCBI chr 2:36,867,436...36,966,749
Ensembl chr 2:36,853,551...36,966,680

G

natriuretic peptide B

increases expression

ISO

1,10-phenanthroline results in increased expression of NPPB mRNA

NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310

G

negative regulator of ubiquitin-like proteins 1

increases expression

ISO

1,10-phenanthroline results in increased expression of NUB1 mRNA

NCBI chr 4:11,335,376...11,366,263
Ensembl chr 4:11,335,883...11,366,462

G

occludin

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [Patulin results in increased degradation of OCLN protein]

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

prolyl 4-hydroxylase subunit alpha 2

increases expression

ISO

1,10-phenanthroline results in increased expression of P4HA2 mRNA

NCBI chr10:38,743,894...38,772,741
Ensembl chr10:38,743,894...38,772,993

G

pyruvate dehydrogenase kinase 1

increases expression

ISO

1,10-phenanthroline results in increased expression of PDK1 mRNA

NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145

G

pyruvate dehydrogenase kinase 3

increases expression

ISO

1,10-phenanthroline results in increased expression of PDK3 mRNA

NCBI chr X:62,480,535...62,547,371
Ensembl chr X:62,480,535...62,547,371

G

phosphoglycerate kinase 1

increases expression

ISO

1,10-phenanthroline results in increased expression of PGK1 mRNA

NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959

G

plasminogen activator, urokinase

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [PLAU protein results in increased activity of MMP9 protein]

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030

G

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

increases expression

ISO

1,10-phenanthroline results in increased expression of PLOD3 mRNA

NCBI chr12:25,313,070...25,323,631
Ensembl chr12:25,313,072...25,323,631

G

protein phosphatase 2 scaffold subunit A beta

decreases expression

ISO

1,10-phenanthroline results in decreased expression of PPP2R1B mRNA

NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:60,081,553...60,125,795

G

phosphoserine phosphatase

decreases expression

ISO

1,10-phenanthroline results in decreased expression of PSPH mRNA

NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180

G

selectin E

multiple interactions

ISO

1,10-phenanthroline affects the reaction [Smoke results in increased expression of SELE protein]

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903

G

serpin family E member 1

increases expression

ISO

1,10-phenanthroline results in increased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

superoxide dismutase 1

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of SOD1 protein]; 1,10-phenanthroline inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in decreased expression of SOD1 protein]

PMID:15629867 PMID:20674559

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in increased expression of SOD2 protein]

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

sterol regulatory element binding transcription factor 1

multiple interactions

ISO

[1,10-phenanthroline results in decreased activity of MBTPS2 protein] which affects the localization of SREBF1 protein; [1,10-phenanthroline results in decreased activity of MBTPS2 protein] which results in decreased cleavage of SREBF1 protein

NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164

G

signal transducer and activator of transcription 3

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [Hydrogen Peroxide affects the localization of STAT3 protein]

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

transferrin receptor

increases expression

ISO

1,10-phenanthroline results in increased expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

translocase of inner mitochondrial membrane 17A

multiple interactions

ISO

1,10-phenanthroline inhibits the reaction [Adenosine Triphosphate results in decreased expression of TIMM17A protein]

NCBI chr13:49,282,918...49,296,363
Ensembl chr13:49,282,918...49,307,904

G

tumor protein p53

affects folding
affects activity

ISO

1,10-phenanthroline affects the folding of TRP53 protein
1,10-phenanthroline analog affects the activity of TP53 protein

PMID:8467489 PMID:35435491

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

vascular endothelial growth factor A

increases expression
multiple interactions

ISO

1,10-phenanthroline results in increased expression of VEGFA mRNA; 1,10-phenanthroline results in increased expression of VEGFA protein
HIF1A protein promotes the reaction [1,10-phenanthroline results in increased expression of VEGFA protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

1,3,4-thiadiazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acyl-CoA synthetase medium-chain family member 3

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of ACSM3 mRNA

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437

G

cytochrome P450, family 11, subfamily a, polypeptide 1

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of CYP11A1 mRNA

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450 family 7 subfamily A member 1

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

fatty acid binding protein 3

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of FABP3 mRNA

NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881

G

fatty acid binding protein 4

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

fatty acid binding protein 5

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of FABP5 mRNA

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

lipoprotein lipase

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of LPL mRNA

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107

G

LDL receptor related protein 12

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of LRP12 mRNA

NCBI chr 7:72,825,979...72,897,308
Ensembl chr 7:72,825,979...72,897,171

G

LDL receptor related protein 1B

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of LRP1B mRNA

NCBI chr 3:45,004,001...47,125,147
Ensembl chr 3:45,004,689...45,957,692

G

peroxisome proliferator-activated receptor gamma

affects expression

EXP

1,3,4-thiadiazole analog affects the expression of PPARG mRNA

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

1,7-phenanthroline

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions

EXP

1,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; 1,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

aldo-keto reductase family 1, member C1

decreases activity

ISO

1,7-phenanthroline results in decreased activity of AKR1C1 protein

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
multiple interactions

EXP

1,7-phenanthroline results in increased expression of CYP1A1 protein
1,7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A1 protein]; 1,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

PMID:1322109 PMID:17967931

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions
increases expression

EXP

1,7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein]
1,7-phenanthroline results in increased expression of CYP1A2 protein

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

POU class 5 homeobox 1

decreases expression

ISO

1,7-phenanthroline results in decreased expression of POU5F1 protein

NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598

G

UDP glucuronosyltransferase family 1 member A6a

multiple interactions
increases expression

EXP

1,7-phenanthroline promotes the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of UGT1A6 protein]
1,7-phenanthroline results in increased expression of UGT1A6 protein

NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acyl-CoA synthetase medium-chain family member 1

affects expression
increases expression

ISO

benzofuran affects the expression of ACSM1 mRNA
benzofuran results in increased expression of ACSM1 mRNA

PMID:17114358 PMID:17311802

NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217

G

aryl hydrocarbon receptor

multiple interactions

EXP

benzofuran binds to and results in increased activity of AHR protein

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

carboxylesterase 1D

affects expression
increases expression

ISO

benzofuran affects the expression of CES1 mRNA
benzofuran results in increased expression of CES1 mRNA

PMID:17114358 PMID:17311802

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

cytochrome P450, family 19, subfamily a, polypeptide 1

decreases activity

ISO

benzofuran analog results in decreased activity of CYP19A1 protein

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases activity

ISO

benzofuran analog results in decreased activity of CYP1A2 protein

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

epoxide hydrolase 1

increases expression
affects expression

ISO

benzofuran results in increased expression of EPHX1 mRNA
benzofuran affects the expression of EPHX1 mRNA

PMID:17114358 PMID:17311802

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

glutathione S-transferase mu 1

affects expression

ISO

benzofuran affects the expression of GSTM1 mRNA

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

affects expression

ISO

benzofuran affects the expression of IKBKG mRNA

NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757

G

inter-alpha trypsin inhibitor, heavy chain 1

affects expression

ISO

benzofuran affects the expression of ITIH1 mRNA

NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853

G

NFE2 like bZIP transcription factor 2

increases activity

ISO

benzofuran results in increased activity of NFE2L2 protein

PMID:30114225 PMID:30203046

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NAD(P)H quinone dehydrogenase 1

increases expression

ISO

benzofuran results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group I, member 3

increases activity

ISO

benzofuran results in increased activity of NR1I3 protein

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

plastin 1

affects expression

ISO

benzofuran affects the expression of PLS1 mRNA

NCBI chr 8:105,196,312...105,306,252
Ensembl chr 8:105,197,455...105,292,447

G

peroxisome proliferator activated receptor alpha

increases expression
increases activity

ISO

benzofuran results in increased expression of PPARA mRNA
benzofuran results in increased activity of PPARA protein

PMID:25689681 PMID:30203046

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

small nucleolar RNA host gene 11

affects expression

ISO

benzofuran affects the expression of SNHG11 mRNA

NCBI chr 3:167,451,272...167,456,945

G

signal transducer and activator of transcription 5B

increases activity

ISO

benzofuran results in increased activity of STAT5B protein

NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990

G

tetratricopeptide repeat domain 39A

affects expression

ISO

benzofuran affects the expression of TTC39A mRNA

NCBI chr 5:129,379,560...129,441,779
Ensembl chr 5:129,380,753...129,433,372

G

UDP-glucose 6-dehydrogenase

affects expression

ISO

benzofuran affects the expression of UGDH mRNA

NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629

10H-phenothiazine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

androgen receptor

affects localization
multiple interactions

ISO

phenothiazine analog affects the localization of AR protein
phenothiazine analog binds to and results in decreased activity of AR protein; phenothiazine inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]

PMID:17606915 PMID:33049310

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

bromodomain containing 4

multiple interactions

ISO

phenothiazine inhibits the reaction [BRD4 protein binds to MED1 protein]

NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923

G

estrogen receptor 1

multiple interactions

ISO

phenothiazine binds to and results in increased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen receptor 2

multiple interactions

ISO

phenothiazine binds to and results in increased activity of ESR2 protein

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709

G

potassium voltage-gated channel subfamily H member 2

decreases activity

ISO

phenothiazine results in decreased activity of KCNH2 protein

NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421

G

kallikrein 1-related peptidase C10

multiple interactions

ISO

phenothiazine analog affects the reaction [Dihydrotestosterone results in increased expression of KLK3 protein]

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586

G

mediator complex subunit 1

multiple interactions

ISO

phenothiazine inhibits the reaction [BRD4 protein binds to MED1 protein]

NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

ISO

phenothiazine binds to and results in increased activity of NR1I2 protein

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

G

peroxisome proliferator-activated receptor gamma

multiple interactions

ISO

phenothiazine binds to and results in increased activity of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

1H-1,2,4-triazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-fetoprotein

multiple interactions

EXP

1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of AFP protein]

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

carbonic anhydrase 1

decreases activity

ISO

1,2,4-triazole analog results in decreased activity of CA1 protein

NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454

G

carbonic anhydrase 2

decreases activity

ISO

1,2,4-triazole analog results in decreased activity of CA2 protein

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064

G

EPH receptor B4

multiple interactions

EXP

1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of EPHB4 protein]

NCBI chr12:24,963,174...24,988,473
Ensembl chr12:24,963,174...24,988,388

G

glutamic--pyruvic transaminase

multiple interactions

EXP

1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased activity of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

vascular endothelial growth factor A

multiple interactions

EXP

1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased expression of VEGFA protein]

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

1H-benzimidazole

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

endothelial PAS domain protein 1

increases stability

EXP

benzimidazole results in increased stability of EPAS1 protein

NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729

G

transient receptor potential cation channel, subfamily V, member 1

multiple interactions

EXP

benzimidazole analog inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein]; benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [benzimidazole analog inhibits the reaction [Protons results in increased activity of TRPV1 protein]]

NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021

1H-imidazo[2,1-i]purine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase

increases metabolic processing

ISO

ALKBH2 protein results in increased metabolism of 1,N(6)-ethenoadenine

NCBI chr12:48,156,825...48,161,489
Ensembl chr12:48,156,827...48,161,483

G

N-methylpurine-DNA glycosylase

increases metabolic processing

ISO

MPG protein results in increased metabolism of 1,N(6)-ethenoadenine

PMID:10626224 PMID:32293880

NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adrenoceptor beta 2

multiple interactions

ISO

imidazole promotes the reaction [Isoproterenol results in increased activity of ADRB2 protein]

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

catalase

decreases activity

ISO

imidazole analog results in decreased activity of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression

EXP

imidazole results in increased expression of CYP2E1 protein

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

decreases activity

ISO

imidazole results in decreased activity of ENPP7 protein

NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,740,763...104,745,760

G

glutathione S-transferase alpha 2

increases expression

EXP

imidazole results in increased expression of GSTA2 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 3

increases expression

EXP

imidazole results in increased expression of GSTA3 mRNA

NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654

G

glutathione S-transferase alpha 5

increases expression

EXP

imidazole results in increased expression of GSTA5 mRNA

NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765

G

glutathione S-transferase mu 1

increases expression

EXP

imidazole results in increased expression of GSTM1 mRNA

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

interleukin 1 beta

multiple interactions

ISO

imidazole results in increased expression of and results in increased secretion of IL1B protein

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

increases expression

ISO

imidazole results in increased expression of IL6 protein

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

short chain dehydrogenase/reductase family 16C, member 5

decreases activity

ISO

imidazole results in decreased activity of SDR16C5 protein

NCBI chr 5:21,816,394...21,841,596
Ensembl chr 5:21,816,394...21,838,551

G

tyrosinase

multiple interactions
increases expression

ISO

Estradiol inhibits the reaction [imidazole results in increased expression of TYR protein]; Estriol inhibits the reaction [imidazole results in increased expression of TYR protein]

NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily B member 1A

increases expression
multiple interactions

ISO

indole results in increased expression of ABCB1 mRNA
indole promotes the reaction [NR1I2 protein binds to ABCB1 promoter]; NR1I2 protein promotes the reaction [indole results in increased expression of ABCB1 mRNA]

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

aryl hydrocarbon receptor

multiple interactions

ISO

indole binds to and results in increased activity of AHR protein; indole results in increased activity of [AHR protein binds to ARNT protein]

PMID:9407059 PMID:28186253

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

ISO

indole results in increased activity of [AHR protein binds to ARNT protein]

NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases expression

ISO

NR1I2 protein promotes the reaction [indole results in increased expression of CYP3A4 mRNA]

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

erythropoietin

multiple interactions

EXP

indole inhibits the reaction [cobaltous chloride results in increased expression of EPO mRNA]; indole inhibits the reaction [cobaltous chloride results in increased expression of EPO protein]

NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725

G

melanocortin 1 receptor

affects binding

ISO

indole analog binds to MC1R protein

NCBI chr19:68,360,950...68,363,877
Ensembl chr19:68,360,950...68,363,877

G

melanocortin 3 receptor

affects binding

ISO

indole analog binds to MC3R protein

NCBI chr 3:181,434,776...181,435,873
Ensembl chr 3:181,434,776...181,435,873

G

melanocortin 4 receptor

affects binding

ISO

indole analog binds to MC4R protein

NCBI chr18:62,689,798...62,691,685

G

melanocortin 5 receptor

affects binding

ISO

indole analog binds to MC5R protein

NCBI chr18:64,185,013...64,190,054
Ensembl chr18:64,185,013...64,190,054

G

nuclear receptor subfamily 1, group I, member 2

multiple interactions

ISO

indole binds to and results in increased activity of NR1I2 protein; indole promotes the reaction [NR1I2 protein binds to ABCB1 promoter]; NR1I2 protein promotes the reaction [indole results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [indole results in increased expression of CYP3A4 mRNA]

NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions
decreases activity

ISO
EXP

pyrazole inhibits the reaction [ADH1 protein results in increased metabolism of Ethanol]
pyrazole results in decreased activity of ADH1 protein

PMID:7646056 PMID:15551062 PMID:16289176

NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291

G

alcohol dehydrogenase 4 (class II), pi polypeptide

decreases activity

EXP

pyrazole results in decreased activity of ADH4 protein

NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879

G

activator of Hsp90 ATPase activity 1

increases expression

ISO

pyrazole results in increased expression of AHSA1 mRNA

NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595

G

AIF family member 3

decreases expression

ISO

pyrazole results in decreased expression of AIFM3 mRNA

NCBI chr11:97,009,100...97,030,601
Ensembl chr11:97,008,426...97,023,334

G

aldo-keto reductase family 1 member A1

multiple interactions

ISO

pyrazole inhibits the reaction [AKR1A1 protein results in increased reduction of muconaldehyde]

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldolase, fructose-bisphosphate C

decreases expression

ISO

pyrazole results in decreased expression of ALDOC mRNA

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133

G

alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase

increases expression

ISO

pyrazole results in increased expression of ALKBH2 mRNA

NCBI chr12:48,156,825...48,161,489
Ensembl chr12:48,156,827...48,161,483

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

ISO

pyrazole results in increased expression of APEX1 mRNA

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

anti-silencing function 1A histone chaperone

increases expression

ISO

pyrazole results in increased expression of ASF1A mRNA

NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639

G

activating transcription factor 4

increases expression

ISO

pyrazole results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

activating transcription factor 5

increases expression

ISO

pyrazole results in increased expression of ATF5 mRNA

NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183

G

activating transcription factor 6

increases expression

ISO

pyrazole results in increased expression of ATF6 mRNA

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

activating transcription factor 6 beta

increases expression

ISO

pyrazole results in increased expression of ATF6B mRNA

NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,095,534...4,106,032

G

BCL2-associated agonist of cell death

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BAD mRNA

NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034

G

BAG cochaperone 3

increases expression

ISO

pyrazole results in increased expression of BAG3 mRNA

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

BCL2-antagonist/killer 1

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BAK1 mRNA

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974

G

BCL2 associated X, apoptosis regulator

increases expression

ISO

pyrazole results in increased expression of BAX mRNA

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

BCL10, immune signaling adaptor

increases expression

ISO

pyrazole results in increased expression of BCL10 mRNA

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829

G

BCL2, apoptosis regulator

decreases expression

ISO

pyrazole results in decreased expression of BCL2 mRNA

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

Bcl2-like 1

decreases expression

ISO

pyrazole results in decreased expression of BCL2L1 mRNA

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 11

increases expression

ISO

pyrazole results in increased expression of BCL2L11 mRNA

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

BCL3, transcription coactivator

increases expression

ISO

pyrazole results in increased expression of BCL3 mRNA

NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368

G

BH3 interacting domain death agonist

increases expression

ISO

pyrazole results in increased expression of BID mRNA

NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275

G

BCL2-interacting killer

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of BIK mRNA

NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317

G

biliverdin reductase A

multiple interactions

ISO

pyrazole results in increased expression of and results in increased activity of BLVRA protein

NCBI chr 3:134,793,397...134,819,367
Ensembl chr 3:134,794,203...134,819,785

G

Bcl2 modifying factor

decreases expression

ISO

pyrazole results in decreased expression of BMF mRNA

NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258

G

BCL2 interacting protein 3

decreases expression

ISO

pyrazole results in decreased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 family apoptosis regulator BOK

decreases expression

ISO

pyrazole results in decreased expression of BOK mRNA

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833

G

BTG anti-proliferation factor 2

increases expression

ISO

pyrazole results in increased expression of BTG2 mRNA

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690

G

carbonic anhydrase 3

decreases expression

ISO

pyrazole results in decreased expression of CAR3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

calreticulin 3

increases expression

ISO

pyrazole results in increased expression of CALR3 mRNA

NCBI chr16:17,430,105...17,456,777
Ensembl chr16:17,430,153...17,457,198

G

caspase 7

decreases expression

ISO

pyrazole results in decreased expression of CASP7 mRNA

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

catalase

multiple interactions

ISO

pyrazole promotes the reaction [triptolide results in decreased activity of CAT protein]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

carbonyl reductase 3

increases expression

ISO

pyrazole results in increased expression of CBR3 mRNA

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558

G

cyclin D1

increases expression
decreases expression

ISO

pyrazole results in increased expression of CCND1 mRNA
pyrazole results in decreased expression of CCND1 protein

PMID:17945193 PMID:33737021

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

chaperonin containing TCP1 subunit 2

increases expression

ISO

pyrazole results in increased expression of CCT2 mRNA

NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977

G

chaperonin containing TCP1 subunit 5

increases expression

ISO

pyrazole results in increased expression of CCT5 mRNA

NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779

G

chaperonin containing TCP1 subunit 7

increases expression

ISO

pyrazole results in increased expression of CCT7 mRNA

NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973

G

cyclin dependent kinase like 2

increases expression

ISO

pyrazole results in increased expression of CDKL2 mRNA

NCBI chr14:16,312,154...16,347,524
Ensembl chr14:16,312,932...16,347,523

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

pyrazole results in increased expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

CCAAT/enhancer binding protein gamma

increases expression

ISO

pyrazole results in increased expression of CEBPG mRNA

NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:96,810,214...96,830,283

G

cell death-inducing DFFA-like effector b

decreases expression

ISO

pyrazole results in decreased expression of CIDEB mRNA

NCBI chr15:33,222,135...33,226,407
Ensembl chr15:33,221,824...33,226,688

G

cell death-inducing DFFA-like effector c

increases expression

ISO

pyrazole results in increased expression of CIDEC mRNA

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

crystallin, alpha B

increases expression

ISO

pyrazole results in increased expression of CRYAB mRNA

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

cytochrome P450, family 17, subfamily a, polypeptide 1

decreases expression

ISO

pyrazole results in decreased expression of CYP17A1 mRNA

NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974

G

cytochrome P450, family 2, subfamily a, polypeptide 3

increases expression

EXP

pyrazole results in increased expression of CYP2A3 mRNA

NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression

ISO

pyrazole results in decreased expression of CYP2C29 mRNA

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

ISO

pyrazole results in decreased expression of CYP2D22 mRNA

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression
increases activity
affects expression

ISO
EXP

pyrazole results in increased expression of CYP2E1 protein
pyrazole results in increased activity of CYP2E1 protein
pyrazole affects the expression of CYP2E1 protein

PMID:3113478 PMID:3782137 PMID:8074729 PMID:8734847 PMID:9698299 More...

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily f, polypeptide 4

decreases expression

ISO

pyrazole results in decreased expression of CYP2F2 mRNA

NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553

G

cytochrome P450, family 2, subfamily j, polypeptide 4

multiple interactions

EXP

pyrazole results in increased expression of and results in increased activity of CYP2J4 protein; pyrazole results in increased stability of and results in increased expression of CYP2J4 mRNA

NCBI chr 5:116,295,691...116,323,219
Ensembl chr 5:116,295,694...116,323,042

G

cytochrome P450, family 2, subfamily r, polypeptide 1

increases expression

ISO

pyrazole results in increased expression of CYP2R1 mRNA

NCBI chr 1:178,166,984...178,232,191
Ensembl chr 1:178,219,704...178,232,423

G

cytochrome P450, family 39, subfamily a, polypeptide 1

decreases expression

ISO

pyrazole results in decreased expression of CYP39A1 mRNA

NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060

G

cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

ISO

pyrazole results in decreased expression of CYP4F14 mRNA

NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612

G

cytochrome P450, family 4, subfamily v, polypeptide 3

decreases expression

ISO

pyrazole results in decreased expression of CYP4V3 mRNA

NCBI chr16:53,650,978...53,675,916
Ensembl chr16:53,650,569...53,676,746

G

cytochrome P450, family 51

increases expression

ISO

pyrazole results in increased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

ISO

pyrazole results in decreased expression of CYP7A1 mRNA

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

ISO

pyrazole results in decreased expression of CYP8B1 mRNA

NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689

G

D-box binding PAR bZIP transcription factor

decreases expression

ISO

pyrazole results in decreased expression of DBP mRNA

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205

G

DNA-damage inducible transcript 3

increases expression

ISO

pyrazole results in increased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4-like

increases expression

ISO

pyrazole results in increased expression of DDIT4L mRNA

NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225

G

derlin 1

increases expression

ISO

pyrazole results in increased expression of DERL1 mRNA

NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678

G

derlin 3

increases expression

ISO

pyrazole results in increased expression of DERL3 mRNA

NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

ISO

pyrazole results in increased expression of DNAJA1 mRNA

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

DnaJ heat shock protein family (Hsp40) member A4

increases expression

ISO

pyrazole results in increased expression of DNAJA4 mRNA

NCBI chr 8:63,975,177...63,998,836
Ensembl chr 8:63,981,559...63,998,836

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

ISO

pyrazole results in increased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

DnaJ heat shock protein family (Hsp40) member B11

increases expression

ISO

pyrazole results in increased expression of DNAJB11 mRNA

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800

G

DnaJ heat shock protein family (Hsp40) member B2

increases expression

ISO

pyrazole results in increased expression of DNAJB2 mRNA

NCBI chr 9:84,179,702...84,187,942
Ensembl chr 9:84,179,695...84,187,942

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression

ISO

pyrazole results in increased expression of DNAJB6 mRNA

NCBI chr 4:6,010,081...6,232,052
Ensembl chr 4:6,128,070...6,232,005

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

ISO

pyrazole results in increased expression of DNAJB9 mRNA

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C10

increases expression

ISO

pyrazole results in increased expression of DNAJC10 mRNA

NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368

G

DnaJ heat shock protein family (Hsp40) member C12

increases expression

ISO

pyrazole results in increased expression of DNAJC12 mRNA

NCBI chr20:25,245,475...25,266,238
Ensembl chr20:25,222,298...25,266,251

G

DnaJ heat shock protein family (Hsp40) member C18

increases expression

ISO

pyrazole results in increased expression of DNAJC18 mRNA

NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535

G

DnaJ heat shock protein family (Hsp40) member C2

increases expression

ISO

pyrazole results in increased expression of DNAJC2 mRNA

NCBI chr 4:14,162,490...14,189,662
Ensembl chr 4:14,163,838...14,192,846

G

dual specificity phosphatase 10

increases expression

ISO

pyrazole results in increased expression of DUSP10 mRNA

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304

G

ER degradation enhancing alpha-mannosidase like protein 1

increases expression

ISO

pyrazole results in increased expression of EDEM1 mRNA

NCBI chr 4:143,350,989...143,385,693
Ensembl chr 4:143,353,624...143,388,060

G

epoxide hydrolase 1

increases expression

ISO

pyrazole results in increased expression of EPHX1 mRNA

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

ISO

pyrazole results in increased expression of ERCC1 mRNA

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120

G

endoplasmic reticulum to nucleus signaling 1

increases expression

ISO

pyrazole results in increased expression of ERN1 mRNA

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791

G

endoplasmic reticulum oxidoreductase 1 alpha

increases expression

ISO

pyrazole results in increased expression of ERO1A mRNA

NCBI chr15:20,974,771...21,010,170
Ensembl chr15:20,972,679...21,018,039

G

endoplasmic reticulum protein 44

increases expression

ISO

pyrazole results in increased expression of ERP44 mRNA

NCBI chr 5:67,313,245...67,406,207
Ensembl chr 5:67,312,098...67,406,444

G

estrogen receptor 1

affects binding

ISO

pyrazole analog binds to ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

estrogen receptor 2

affects binding

ISO

pyrazole analog binds to ESR2 protein

NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709

G

FKBP prolyl isomerase 11

increases expression

ISO

pyrazole results in increased expression of FKBP11 mRNA

NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123

G

FKBP prolyl isomerase 1A

increases expression

ISO

pyrazole results in increased expression of FKBP1A mRNA

NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233

G

forkhead box O3

decreases expression

ISO

pyrazole results in decreased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

ISO

pyrazole results in decreased expression of G6PC1 mRNA

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

glucose-6-phosphate dehydrogenase

multiple interactions

ISO

G6PDX affects the reaction [pyrazole results in increased expression of and results in increased activity of CYP2A5 protein]; G6PDX affects the reaction [pyrazole results in increased expression of CYP2A5 mRNA]; G6PDX affects the reaction [pyrazole results in increased expression of HSPA5 protein]

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO

pyrazole results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

1,4-alpha-glucan branching enzyme 1

increases expression

ISO

pyrazole results in increased expression of GBE1 mRNA

NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638

G

glucokinase

decreases expression

ISO

pyrazole results in decreased expression of GCK mRNA

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glutamate-cysteine ligase, catalytic subunit

increases expression

ISO

pyrazole results in increased expression of GCLC mRNA

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamic--pyruvic transaminase

multiple interactions

ISO

pyrazole promotes the reaction [triptolide results in increased activity of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 2

increases expression

ISO

pyrazole results in increased expression of GPX2 mRNA

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione-disulfide reductase

increases expression

ISO

pyrazole results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

increases expression

ISO

pyrazole results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

glutathione S-transferase alpha 2

increases expression

ISO

pyrazole results in increased expression of GSTA1 mRNA

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase, C-terminal domain containing

increases expression

ISO

pyrazole results in increased expression of GSTCD mRNA

NCBI chr 2:224,173,764...224,268,743
Ensembl chr 2:224,173,473...224,265,680

G

glutathione S-transferase kappa 1

decreases expression

ISO

pyrazole results in decreased expression of GSTK1 mRNA

NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927

G

glutathione S-transferase mu 1

increases expression

ISO

pyrazole results in increased expression of GSTM1 mRNA; pyrazole results in increased expression of GSTM1 protein

PMID:14610226 PMID:17945193

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 4

increases expression

ISO

pyrazole results in increased expression of GSTM4 mRNA

NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638

G

glutathione S-transferase theta 1

decreases expression

ISO

pyrazole results in decreased expression of GSTT1 mRNA

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019

G

glycogenin 1

increases expression

ISO

pyrazole results in increased expression of GYG1 mRNA

NCBI chr 2:104,540,927...104,583,038
Ensembl chr 2:104,540,533...104,582,818

G

glycogen synthase 2

decreases expression

ISO

pyrazole results in decreased expression of GYS2 mRNA

NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:177,096,063...177,137,236

G

H2A.X variant histone

increases expression

ISO

pyrazole results in increased expression of H2AX mRNA

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

heme oxygenase 1

increases expression
multiple interactions

ISO

pyrazole results in increased expression of HMOX1 mRNA
pyrazole results in increased expression of and results in increased activity of HMOX1 protein

PMID:17945193 PMID:25478736

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heterogeneous nuclear ribonucleoprotein A1

multiple interactions
increases expression

ISO

pyrazole promotes the reaction [HNRNPA1 protein binds to CYP2A5 mRNA]
pyrazole results in increased expression of HNRNPA1 protein

NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression

ISO

pyrazole results in decreased expression of HSD3B2 mRNA

NCBI chr 2:188,858,574...188,864,694

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3

decreases expression

ISO

pyrazole results in decreased expression of HSD3B3 mRNA

NCBI chr 2:188,826,756...188,832,734
Ensembl chr 2:188,826,110...188,904,981

G

heat shock protein 90 alpha family class A member 1

increases expression

ISO

pyrazole results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein 90 alpha family class B member 1

increases expression

ISO

pyrazole results in increased expression of HSP90AB1 mRNA

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926

G

heat shock protein 90 beta family member 1

increases expression

ISO

pyrazole results in increased expression of HSP90B1 mRNA

NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:22,997,962...23,012,293

G

heat shock protein family A (Hsp70) member 13

increases expression

ISO

pyrazole results in increased expression of HSPA13 mRNA

NCBI chr11:27,862,717...27,876,898
Ensembl chr11:27,862,593...27,876,898

G

heat shock protein family A (Hsp70) member 1A

increases expression

ISO

pyrazole results in increased expression of HSPA1A mRNA

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1B

increases expression

ISO

pyrazole results in increased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 4

increases expression

ISO

pyrazole results in increased expression of HSPA4 mRNA

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835

G

heat shock protein family A (Hsp70) member 4 like

increases expression

ISO

pyrazole results in increased expression of HSPA4L mRNA

NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986

G

heat shock protein family A (Hsp70) member 5

multiple interactions
increases expression

ISO

G6PDX affects the reaction [pyrazole results in increased expression of HSPA5 protein]; Vitamin E inhibits the reaction [pyrazole results in increased expression of HSPA5 protein]
pyrazole results in increased expression of HSPA5 mRNA; pyrazole results in increased expression of HSPA5 protein

PMID:12499123 PMID:14610226 PMID:17945193 PMID:18068688

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 8

increases expression

ISO

pyrazole results in increased expression of HSPA8 mRNA

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family A (Hsp70) member 9

increases expression

ISO

pyrazole results in increased expression of HSPA9 mRNA

NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398

G

heat shock protein family B (small) member 1

increases expression

ISO

pyrazole results in increased expression of HSPB1 mRNA

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family B (small) member 8

increases expression

ISO

pyrazole results in increased expression of HSPB8 mRNA

NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937

G

heat shock protein family E (Hsp10) member 1

increases expression

ISO

pyrazole results in increased expression of HSPE1 mRNA

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

heat shock protein family H (Hsp110) member 1

increases expression

ISO

pyrazole results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

interleukin 1 beta

multiple interactions

ISO

pyrazole analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

multiple interactions

ISO

pyrazole analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 protein]

PMID:33094891 PMID:34758665

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

DNA ligase 3

increases expression

ISO

pyrazole results in increased expression of LIG3 mRNA

NCBI chr10:68,215,371...68,238,705
Ensembl chr10:68,215,407...68,238,704

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

ISO

pyrazole results in increased expression of MCL1 mRNA

NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782

G

marker of proliferation Ki-67

decreases expression

ISO

pyrazole results in decreased expression of MKI67 protein

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

NFE2 like bZIP transcription factor 2

affects localization

ISO

pyrazole affects the localization of NFE2L2 protein

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NFKB inhibitor alpha

multiple interactions

ISO

pyrazole analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

nucleolar protein 3

increases expression

ISO

pyrazole results in increased expression of NOL3 mRNA

NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722

G

nucleophosmin/nucleoplasmin, 3

increases expression

ISO

pyrazole results in increased expression of NPM3 mRNA

NCBI chr 1:254,544,664...254,546,649
Ensembl chr 1:254,544,664...254,546,649

G

NAD(P)H quinone dehydrogenase 1

increases expression

ISO

pyrazole results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear protein 1, transcriptional regulator

increases expression

ISO

pyrazole results in increased expression of NUPR1 mRNA

NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901

G

8-oxoguanine DNA glycosylase

increases expression

ISO

pyrazole results in increased expression of OGG1 mRNA

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604

G

pro-apoptotic WT1 regulator

increases expression

ISO

pyrazole results in increased expression of PAWR mRNA

NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492

G

pyruvate carboxylase

decreases expression

ISO

pyrazole results in decreased expression of PCX mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940

G

phosphoenolpyruvate carboxykinase 1

decreases expression

ISO

pyrazole results in decreased expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561

G

protein disulfide isomerase family A, member 3

increases expression

ISO

pyrazole results in increased expression of PDIA3 mRNA

NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327

G

protein disulfide isomerase family A, member 4

increases expression

ISO

pyrazole results in increased expression of PDIA4 mRNA

NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191

G

protein disulfide isomerase family A, member 6

increases expression

ISO

pyrazole results in increased expression of PDIA6 mRNA

NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091

G

prefoldin subunit 4

increases expression

ISO

pyrazole results in increased expression of PFDN4 mRNA

NCBI chr 3:179,721,765...179,729,901
Ensembl chr 3:179,719,344...179,729,901

G

phosphofructokinase, liver type

decreases expression

ISO

pyrazole results in decreased expression of PFKL mRNA

NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966

G

PGAM family member 5, mitochondrial serine/threonine protein phosphatase

increases expression

ISO

pyrazole results in increased expression of PGAM5 mRNA

NCBI chr12:52,069,023...52,076,131
Ensembl chr12:52,069,103...52,076,131

G

phosphoglycerate kinase 2

increases expression

ISO

pyrazole results in increased expression of PGK2 mRNA

NCBI chr 9:27,976,913...27,978,479
Ensembl chr 9:27,973,459...28,079,866

G

phosphoglucomutase 1

increases expression

ISO

pyrazole results in increased expression of PGM1 mRNA

NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:119,710,737...119,770,159

G

phosphoglucomutase 3

increases expression

ISO

pyrazole results in increased expression of PGM3 mRNA

NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021

G

phosphomannomutase 1

increases expression

ISO

pyrazole results in increased expression of PMM1 mRNA

NCBI chr 7:115,346,767...115,357,137
Ensembl chr 7:115,346,771...115,357,024

G

proteasome maturation protein

increases expression

ISO

pyrazole results in increased expression of POMP mRNA

NCBI chr12:12,198,262...12,212,132
Ensembl chr12:12,198,263...12,210,880

G

peroxisome proliferator-activated receptor gamma

increases expression

ISO

pyrazole results in increased expression of PPARG mRNA

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

decreases expression

ISO

pyrazole results in decreased expression of PPARGC1A mRNA

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

peptidylprolyl isomerase A

increases expression

ISO

pyrazole results in increased expression of PPIA mRNA

NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115

G

peptidylprolyl isomerase D

increases expression

ISO

pyrazole results in increased expression of PPID mRNA

NCBI chr 2:167,025,985...167,037,998
Ensembl chr 2:167,025,931...167,054,493

G

peroxiredoxin 2

decreases expression

ISO

pyrazole results in decreased expression of PRDX2 mRNA

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006

G

pre-mRNA processing factor 19

increases expression

ISO

pyrazole results in increased expression of PRPF19 mRNA

NCBI chr 1:216,966,104...216,977,549
Ensembl chr 1:216,966,462...216,980,506

G

phosphoserine aminotransferase 1

increases expression

ISO

pyrazole results in increased expression of PSAT1 mRNA

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693

G

proteasome 20S subunit alpha 1

increases expression

ISO

pyrazole results in increased expression of PSMA1 mRNA

NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949

G

proteasome 20S subunit alpha 2

increases expression

ISO

pyrazole results in increased expression of PSMA2 mRNA

NCBI chr17:55,250,054...55,260,441
Ensembl chr17:55,247,442...55,339,673

G

proteasome 20S subunit alpha 4

increases expression

ISO

pyrazole results in increased expression of PSMA4 mRNA

NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979

G

proteasome 20S subunit alpha 5

increases expression

ISO

pyrazole results in increased expression of PSMA5 mRNA

NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867

G

proteasome 20S subunit alpha 7

increases expression

ISO

pyrazole results in increased expression of PSMA7 mRNA

NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253

G

proteasome 20S subunit beta 2

increases expression

ISO

pyrazole results in increased expression of PSMB2 mRNA

NCBI chr 5:144,255,058...144,287,200
Ensembl chr 5:144,255,026...144,287,608

G

proteasome 20S subunit beta 3

increases expression

ISO

pyrazole results in increased expression of PSMB3 mRNA

NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883

G

proteasome 20S subunit beta 4

increases expression

ISO

pyrazole results in increased expression of PSMB4 mRNA

NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287

G

proteasome 20S subunit beta 5

increases expression

ISO

pyrazole results in increased expression of PSMB5 mRNA

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 26S subunit, ATPase 2

increases expression

ISO

pyrazole results in increased expression of PSMC2 mRNA

NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390

G

proteasome 26S subunit, ATPase 3

increases expression

ISO

pyrazole results in increased expression of PSMC3 mRNA

NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176

G

proteasome 26S subunit, ATPase 4

increases expression

ISO

pyrazole results in increased expression of PSMC4 mRNA

NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060

G

proteasome 26S subunit, ATPase 6

increases expression

ISO

pyrazole results in increased expression of PSMC6 mRNA

NCBI chr15:21,022,314...21,043,785
Ensembl chr15:21,022,314...21,043,785

G

proteasome 26S subunit, non-ATPase 11

increases expression

ISO

pyrazole results in increased expression of PSMD11 mRNA

NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234

G

proteasome 26S subunit, non-ATPase 12

increases expression

ISO

pyrazole results in increased expression of PSMD12 mRNA

NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964

G

proteasome 26S subunit, non-ATPase 14

increases expression

ISO

pyrazole results in increased expression of PSMD14 mRNA

NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:66,662,900...66,755,665

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 2

increases expression

ISO

pyrazole results in increased expression of PSMD2 mRNA

NCBI chr11:93,752,761...93,763,388
Ensembl chr11:93,752,763...93,763,388

G

proteasome 26S subunit, non-ATPase 3

increases expression

ISO

pyrazole results in increased expression of PSMD3 mRNA

NCBI chr10:84,139,249...84,151,879
Ensembl chr10:84,139,677...84,151,878

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 4

increases expression

ISO

pyrazole results in increased expression of PSMD4 mRNA

NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201

G

proteasome 26S subunit, non-ATPase 5

increases expression

ISO

pyrazole results in increased expression of PSMD5 mRNA

NCBI chr 3:38,531,206...38,552,085
Ensembl chr 3:38,530,951...38,548,490

G

proteasome 26S subunit, non-ATPase 6

increases expression

ISO

pyrazole results in increased expression of PSMD6 mRNA

NCBI chr15:13,532,675...13,542,682
Ensembl chr15:13,532,675...13,542,682

G

proteasome 26S subunit, non-ATPase 7

increases expression

ISO

pyrazole results in increased expression of PSMD7 mRNA

NCBI chr19:52,404,032...52,411,316
Ensembl chr19:52,404,032...52,417,871

G

proteasome 26S subunit, non-ATPase 8

increases expression

ISO

pyrazole results in increased expression of PSMD8 mRNA

NCBI chr 1:93,601,857...93,608,689
Ensembl chr 1:93,601,853...93,608,689

G

proteasome activator subunit 3

increases expression

ISO

pyrazole results in increased expression of PSME3 mRNA

NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033

G

phosphatase and tensin homolog

decreases expression

ISO

pyrazole results in decreased expression of PTEN mRNA

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330

G

glycogen phosphorylase L

decreases expression

ISO

pyrazole results in decreased expression of PYGL mRNA

NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269

G

quiescin sulfhydryl oxidase 2

increases expression

ISO

pyrazole results in increased expression of QSOX2 mRNA

NCBI chr 3:29,433,091...29,462,739
Ensembl chr 3:29,433,091...29,463,036

G

RAD1 checkpoint DNA exonuclease

increases expression

ISO

pyrazole results in increased expression of RAD1 mRNA

NCBI chr 2:61,188,755...61,196,868
Ensembl chr 2:61,188,727...61,196,867

G

RAD18 E3 ubiquitin protein ligase

increases expression

ISO

pyrazole results in increased expression of RAD18 mRNA

NCBI chr 4:147,291,463...147,376,904
Ensembl chr 4:147,291,276...147,376,869

G

RAD51 paralog B

increases expression

ISO

pyrazole results in increased expression of RAD51B mRNA

NCBI chr 6:103,829,390...104,373,923
Ensembl chr 6:103,829,554...104,374,509

G

RAD52 homolog, DNA repair protein

increases expression

ISO

pyrazole results in increased expression of RAD52 mRNA

NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:154,778,320...154,800,021

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

ISO

pyrazole promotes the reaction [triptolide results in increased phosphorylation of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

rhotekin

increases expression

ISO

pyrazole results in increased expression of RTKN mRNA

NCBI chr 4:117,198,496...117,215,660
Ensembl chr 4:117,198,647...117,215,660

G

serpin family A member 7

increases expression

ISO

pyrazole results in increased expression of SERPINA7 mRNA

NCBI chr X:107,452,044...107,510,958
Ensembl chr X:107,452,044...107,457,681

G

superoxide dismutase 2

decreases expression

ISO

pyrazole results in decreased expression of SOD2 mRNA

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

sphingosine kinase 2

decreases expression

ISO

pyrazole results in decreased expression of SPHK2 mRNA

NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:105,317,333...105,321,637

G

small proline-rich protein 1A

increases expression

ISO

pyrazole results in increased expression of SPRR1A mRNA

NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:180,750,709...180,752,991

G

sulfiredoxin 1

increases expression

ISO

pyrazole results in increased expression of SRXN1 mRNA

NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765

G

sulfotransferase family 1B member 1

decreases expression

ISO

pyrazole results in decreased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549

G

t-complex 1

increases expression

ISO

pyrazole results in increased expression of TCP1 mRNA

NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527

G

thymidine kinase 1

decreases expression

ISO

pyrazole results in decreased expression of TK1 mRNA

NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228

G

tumor necrosis factor

multiple interactions

ISO

pyrazole analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pyrazole promotes the reaction [triptolide results in increased expression of TNF mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of TNF protein]

PMID:33094891 PMID:34758665

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF alpha induced protein 1

increases expression

ISO

pyrazole results in increased expression of TNFAIP1 mRNA

NCBI chr10:63,915,824...63,930,514
Ensembl chr10:63,915,825...63,930,514

G

TNF superfamily member 9

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of TNFSF9 mRNA

NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339

G

tumor protein p53

increases expression

ISO

pyrazole results in increased expression of TRP53 mRNA

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p53 binding protein 1

increases expression

ISO

pyrazole results in increased expression of TRP53BP1 mRNA

NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747

G

tumor protein p53 inducible nuclear protein 1

increases expression

ISO

pyrazole results in increased expression of TRP53INP1 mRNA

NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484

G

Tnf receptor-associated factor 2

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in decreased expression of TRAF2 mRNA

NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691

G

TRAF-interacting protein

multiple interactions

EXP

[Ethanol co-treated with pyrazole co-treated with Carbon Tetrachloride] results in increased expression of TRAIP mRNA

NCBI chr 8:117,520,476...117,540,253
Ensembl chr 8:117,520,441...117,540,253

G

thioredoxin-like 1

increases expression

ISO

pyrazole results in increased expression of TXNL1 mRNA

NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518

G

thioredoxin reductase 1

increases expression

ISO

pyrazole results in increased expression of TXNRD1 mRNA

NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817

G

ubiquitin-like modifier activating enzyme 5

increases expression

ISO

pyrazole results in increased expression of UBA5 mRNA

NCBI chr 8:113,544,037...113,559,711
Ensembl chr 8:113,544,037...113,559,711

G

ubiquitin-associated protein 1

increases expression

ISO

pyrazole results in increased expression of UBAP1 mRNA

NCBI chr 5:61,316,650...61,357,077
Ensembl chr 5:61,316,643...61,357,076

G

ubiquitin-conjugating enzyme E2F (putative)

increases expression

ISO

pyrazole results in increased expression of UBE2F mRNA

NCBI chr 9:99,293,506...99,328,690
Ensembl chr 9:99,293,515...99,330,479

G

ubiquitin-conjugating enzyme E2I

increases expression

ISO

pyrazole results in increased expression of UBE2I mRNA

NCBI chr10:14,782,245...14,802,911
Ensembl chr10:70,199,041...70,199,866
Ensembl chr10:70,199,041...70,199,866

G

ubiquitin-conjugating enzyme E2L 3

increases expression

ISO

pyrazole results in increased expression of UBE2L3 mRNA

NCBI chr11:97,300,584...97,343,084
Ensembl chr11:97,301,945...97,343,084

G

ubiquitin conjugating enzyme E2 U

decreases expression

ISO

pyrazole results in decreased expression of UBE2U mRNA

NCBI chr 5:120,233,749...120,301,514
Ensembl chr 5:120,233,983...120,301,512

G

ubiquitination factor E4B

increases expression

ISO

pyrazole results in increased expression of UBE4B mRNA

NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:165,049,897...165,153,572

G

ubiquitin-like 4A

increases expression

ISO

pyrazole results in increased expression of UBL4A mRNA

NCBI chr X:157,302,528...157,305,380
Ensembl chr X:157,304,254...157,305,380

G

ubiquitin protein ligase E3 component n-recognin 2

decreases expression

ISO

pyrazole results in decreased expression of UBR2 mRNA

NCBI chr 9:21,480,058...21,559,936
Ensembl chr 9:21,480,037...21,559,936

G

ubiquitin C-terminal hydrolase L3

increases expression

ISO

pyrazole results in increased expression of UCHL3 mRNA

NCBI chr15:84,888,847...84,942,095
Ensembl chr15:84,899,806...84,942,095
Ensembl chr 3:84,899,806...84,942,095

G

ubiquitin recognition factor in ER associated degradation 1

increases expression

ISO

pyrazole results in increased expression of UFD1 mRNA

NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434

G

ubiquitin-fold modifier 1

increases expression

ISO

pyrazole results in increased expression of UFM1 mRNA

NCBI chr 2:140,119,722...140,127,866
Ensembl chr 2:140,119,725...140,127,866

G

UDP glucuronosyltransferase 2 family, polypeptide B34

increases expression

ISO

pyrazole results in increased expression of UGT2B34 mRNA

NCBI chr14:21,436,939...21,483,494
Ensembl chr14:21,462,841...21,483,494

G

uracil-DNA glycosylase

increases expression

ISO

pyrazole results in increased expression of UNG mRNA

NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257

G

uridine phosphorylase 2

decreases expression

ISO

pyrazole results in decreased expression of UPP2 mRNA

NCBI chr 3:63,681,671...63,726,194
Ensembl chr 3:63,681,826...63,726,191

G

ubiquitin specific peptidase 14

increases expression

ISO

pyrazole results in increased expression of USP14 mRNA

NCBI chr18:1,292,745...1,330,867
Ensembl chr18:1,292,745...1,330,336

G

ubiquitin specific peptidase 2

decreases expression

ISO

pyrazole results in decreased expression of USP2 mRNA

NCBI chr 8:53,308,264...53,336,800
Ensembl chr 8:53,308,303...53,336,794

G

ubiquitin specific peptidase 22

increases expression

ISO

pyrazole results in increased expression of USP22 mRNA

NCBI chr10:46,328,092...46,354,939
Ensembl chr10:46,328,092...46,371,723

G

valosin-containing protein

increases expression

ISO

pyrazole results in increased expression of VCP mRNA

NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387

G

X-ray repair cross complementing 4

increases expression

ISO

pyrazole results in increased expression of XRCC4 mRNA

NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160

4,7-phenanthroline

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

decreases activity
multiple interactions

ISO
EXP

4,7-phenanthroline results in decreased activity of AHR protein
4,7-phenanthroline inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]
4,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; 4,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

PMID:1322109 PMID:8738555

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

EXP

4,7-phenanthroline inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 enhancer]]

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions

EXP
ISO

carbazole binds to and results in increased activity of AHR protein

PMID:21431309 PMID:28186253

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

estrogen receptor 1

multiple interactions

ISO

benzothiophene analog binds to and results in increased activity of ESR1 protein

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions
increases activity

ISO

norharman inhibits the reaction [Lipids metabolite results in increased activity of AHR protein]
norharman results in increased activity of AHR protein

PMID:27020609 PMID:28336214

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

caspase 3

increases cleavage
increases expression

ISO

norharman results in increased cleavage of CASP3 protein
norharman results in increased expression of CASP3 mRNA

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 7

increases expression

ISO

norharman results in increased expression of CASP7 mRNA

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 9

increases expression

ISO

norharman results in increased expression of CASP9 mRNA

Ensembl chr 5:159,391,188...159,409,648

G

catalase

decreases activity

ISO

norharman results in decreased activity of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases expression

ISO

CYP1A1 protein affects the metabolism of [norharman co-treated with aniline]
norharman results in increased expression of CYP1A1 mRNA; norharman results in increased expression of CYP1A1 protein

PMID:15279827 PMID:28336214

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

ISO

CYP1A2 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions

ISO

CYP1B1 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

ISO

CYP2B6 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, family 2, subfamily d, polypeptide 4

multiple interactions

ISO

CYP2D6 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

ISO

CYP2E1 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

ISO

CYP3A4 protein affects the metabolism of [norharman co-treated with aniline]

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

monoamine oxidase A

decreases activity

ISO

norharman results in decreased activity of MAOA protein

NCBI chr X:8,615,239...8,681,372
Ensembl chr X:8,615,239...8,682,631

G

monoamine oxidase B

multiple interactions
decreases activity

ISO

norharman inhibits the reaction [MAOB protein results in increased oxidation of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine]
norharman results in decreased activity of MAOB protein

NCBI chr X:8,490,405...8,594,065
Ensembl chr X:8,490,344...8,594,375

G

NFE2 like bZIP transcription factor 2

increases expression

ISO

norharman results in increased expression of NFE2L2 protein

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

NAD(P)H quinone dehydrogenase 1

increases expression

ISO

norharman results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

poly (ADP-ribose) polymerase 1

increases cleavage

ISO

norharman results in increased cleavage of PARP1 protein

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

solute carrier family 22 member 1

decreases activity
multiple interactions

ISO

norharman results in decreased activity of SLC22A1 protein
norharman inhibits the reaction [SLC22A1 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436

G

solute carrier family 22 member 2

decreases activity
multiple interactions

ISO

norharman results in decreased activity of SLC22A2 protein
norharman inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019

G

solute carrier family 22 member 3

decreases activity
multiple interactions

ISO

norharman results in decreased activity of SLC22A3 protein
norharman inhibits the reaction [SLC22A3 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]

NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353

G

tumor protein p53

affects activity

ISO

norharman metabolite affects the activity of TP53 protein

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions

EXP
ISO

carbazole binds to and results in increased activity of AHR protein

PMID:21431309 PMID:28186253

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

atypical chemokine receptor 3

increases expression

EXP

dibenzofuran analog results in increased expression of ACKR3 mRNA

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

increases expression

EXP

dibenzofuran analog results in increased expression of ADH7 mRNA

NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691

G

aryl hydrocarbon receptor

multiple interactions
increases activity
affects localization

EXP
ISO

AHR protein promotes the reaction [dibenzofuran analog results in increased expression of CDKN1A mRNA]; AHR protein promotes the reaction [dibenzofuran analog results in increased expression of CDKN1B mRNA]; AHR protein promotes the reaction [dibenzofuran analog results in increased expression of GSTA2 mRNA]; AHR protein promotes the reaction [dibenzofuran analog results in increased expression of PLA2G2A mRNA]; AHR protein promotes the reaction [dibenzofuran analog results in increased expression of PTGS2 mRNA]; dibenzofuran binds to and results in increased activity of AHR protein
dibenzofuran analog results in increased activity of AHR protein
dibenzofuran analog affects the localization of AHR protein

PMID:20566336 PMID:21431309 PMID:28186253 PMID:28669845

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

aryl-hydrocarbon receptor repressor

increases expression

EXP

dibenzofuran analog results in increased expression of AHRR mRNA

NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866

G

aldehyde dehydrogenase 3 family, member A1

increases expression

EXP

dibenzofuran analog results in increased expression of ALDH3A1 mRNA

NCBI chr10:46,392,464...46,402,151
Ensembl chr10:46,392,411...46,402,151

G

aldehyde dehydrogenase 3 family, member A2

increases expression

EXP

dibenzofuran analog results in increased expression of ALDH3A2 mRNA

NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648

G

aurora kinase B

decreases expression

EXP

dibenzofuran analog results in decreased expression of AURKB mRNA

NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285

G

BRCA1 associated RING domain 1

decreases expression

EXP

dibenzofuran analog results in decreased expression of BARD1 mRNA

NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:80,069,960...80,176,873

G

BRCA1, DNA repair associated

decreases expression

EXP

dibenzofuran analog results in decreased expression of BRCA1 mRNA

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

BRCA2, DNA repair associated

decreases expression

EXP

dibenzofuran analog results in decreased expression of BRCA2 mRNA

NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194

G

C-C motif chemokine ligand 20

increases expression

EXP

dibenzofuran analog results in increased expression of CCL20 mRNA

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736

G

cyclin A2

decreases expression

EXP

dibenzofuran analog results in decreased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin B1

decreases expression

EXP

dibenzofuran analog results in decreased expression of CCNB1 mRNA

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

EXP

dibenzofuran analog results in increased expression of CDKN1A mRNA
AHR protein promotes the reaction [dibenzofuran analog results in increased expression of CDKN1A mRNA]

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

increases expression
multiple interactions

EXP

dibenzofuran analog results in increased expression of CDKN1B mRNA; dibenzofuran analog results in increased expression of CDKN1B protein
AHR protein promotes the reaction [dibenzofuran analog results in increased expression of CDKN1B mRNA]

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

cannabinoid receptor 1

multiple interactions

EXP

dibenzofuran analog inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR1 protein]

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

cannabinoid receptor 2

multiple interactions

ISO

dibenzofuran analog inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein]

NCBI chr 5:153,408,968...153,435,092
Ensembl chr 5:153,409,147...153,435,961

G

cytochrome c oxidase subunit 4i2

decreases expression

EXP

dibenzofuran analog results in decreased expression of COX4I2 mRNA

NCBI chr 3:161,686,193...161,699,605
Ensembl chr 3:161,689,017...161,699,602

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases expression

EXP

2,2',4,4',5-brominated diphenyl ether inhibits the reaction [dibenzofuran analog results in increased expression of CYP1A1 mRNA]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [dibenzofuran analog results in increased expression of CYP1A1 mRNA]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [dibenzofuran analog results in increased expression of CYP1A1 protein]
dibenzofuran analog results in increased expression of CYP1A1 mRNA; dibenzofuran analog results in increased expression of CYP1A1 protein

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases activity
multiple interactions

ISO

dibenzofuran results in increased activity of CYP1A2 protein
dibenzofuran metabolite results in increased activity of CYP1A2 protein
[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA

PMID:7750161 PMID:8001243 PMID:26032510

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 2, subfamily f, polypeptide 4

increases expression

EXP

dibenzofuran analog results in increased expression of CYP2F4 mRNA

NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553

G

ectonucleoside triphosphate diphosphohydrolase 1

increases expression

EXP

dibenzofuran analog results in increased expression of ENTPD1 mRNA

NCBI chr 1:249,374,810...249,502,310
Ensembl chr 1:249,374,836...249,502,317

G

glutathione S-transferase alpha 2

multiple interactions
increases expression

EXP

AHR protein promotes the reaction [dibenzofuran analog results in increased expression of GSTA2 mRNA]

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

dibenzofuran analog results in increased expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

microtubule-associated protein 1 light chain 3 beta

affects localization
increases expression

ISO

dibenzofuran affects the localization of MAP1LC3B protein
dibenzofuran results in increased expression of MAP1LC3B protein modified form

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358

G

neuronal pentraxin receptor

increases expression

EXP

dibenzofuran analog results in increased expression of NPTXR mRNA

NCBI chr 7:113,217,046...113,235,122
Ensembl chr 7:113,217,050...113,235,156

G

NAD(P)H quinone dehydrogenase 1

increases expression

EXP

dibenzofuran analog results in increased expression of NQO1 mRNA

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group D, member 2

increases expression

EXP

dibenzofuran analog results in increased expression of NR1D2 mRNA

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330

G

phospholipase A2 group IIA

multiple interactions
increases expression

EXP

AHR protein promotes the reaction [dibenzofuran analog results in increased expression of PLA2G2A mRNA]

NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297

G

prostaglandin E synthase

increases expression

EXP

dibenzofuran analog results in increased expression of PTGES mRNA

NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

EXP

dibenzofuran analog results in increased expression of PTGS2 mRNA
AHR protein promotes the reaction [dibenzofuran analog results in increased expression of PTGS2 mRNA]

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RAD51 recombinase

decreases expression

EXP

dibenzofuran analog results in decreased expression of RAD51 mRNA

NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469

G

retinol binding protein 4

increases expression

EXP

dibenzofuran analog results in increased expression of RBP4 mRNA

NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898

G

serpin family E member 1

increases expression

EXP

dibenzofuran analog results in increased expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

SIM bHLH transcription factor 2

increases expression

EXP

dibenzofuran analog results in increased expression of SIM2 mRNA

NCBI chr11:46,883,859...46,923,305
Ensembl chr11:46,883,859...46,923,305

G

sequestosome 1

decreases expression

ISO

dibenzofuran results in decreased expression of SQSTM1 protein

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750

G

TCDD-inducible poly(ADP-ribose) polymerase

increases expression

EXP

dibenzofuran analog results in increased expression of TIPARP mRNA

NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:152,063,751...152,090,406

G

transmembrane protein 150A

increases expression

EXP

dibenzofuran analog results in increased expression of TMEM150A mRNA

NCBI chr 4:105,968,526...105,972,822
Ensembl chr 4:105,968,702...105,972,822

G

DNA topoisomerase II alpha

decreases expression

EXP

dibenzofuran analog results in decreased expression of TOP2A mRNA

NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366

dibenzothiophene

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aryl hydrocarbon receptor

multiple interactions

EXP

dibenzothiophene binds to and results in increased activity of AHR protein

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

estrogen receptor 1

increases expression

ISO

dibenzothiophene results in increased expression of ESR1 mRNA

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

increases expression

ISO

dibenzothiophene results in increased expression of HSD3B1 mRNA

NCBI chr 2:188,858,574...188,864,694

G

prokineticin 1

increases expression

ISO

dibenzothiophene results in increased expression of PROK1 mRNA

NCBI chr 2:197,538,747...197,547,550
Ensembl chr 2:197,537,068...197,547,550

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 1700009N14 gene like

increases methylation

EXP

furan results in increased methylation of 1700009N14RIKL gene

NCBI chr 5:59,252,092...59,253,468
Ensembl chr 5:59,251,970...59,265,163

G

RIKEN cDNA 1700012B07 gene like

increases methylation

EXP

furan results in increased methylation of 1700012B07RIKL gene

NCBI chr10:95,271,034...95,304,337
Ensembl chr10:95,268,422...95,304,315

G

APOBEC1 complementation factor

increases methylation

EXP

furan results in increased methylation of A1CF gene

NCBI chr 1:239,149,436...239,242,460
Ensembl chr 1:239,149,493...239,236,817

G

alpha-2-macroglobulin

decreases expression
increases expression

EXP

furan results in decreased expression of A2M mRNA
furan results in increased expression of A2M mRNA

PMID:15120968 PMID:26194646

NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:156,569,860...156,619,868

G

alpha 1,3-galactosyltransferase 2

increases expression

EXP

furan results in increased expression of A3GALT2 mRNA

NCBI chr 5:146,385,725...146,398,156
Ensembl chr 5:146,385,746...146,400,043

G

alpha 1,4-galactosyltransferase

increases expression

EXP

furan results in increased expression of A4GALT mRNA

NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:116,247,880...116,273,171

G

acetoacetyl-CoA synthetase

decreases methylation
increases expression

EXP

furan results in decreased methylation of AACS gene
furan results in increased expression of AACS mRNA

NCBI chr12:36,774,471...36,817,835
Ensembl chr12:36,774,471...36,822,543

G

arylacetamide deacetylase

decreases expression

EXP

furan results in decreased expression of AADAC mRNA

NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525

G

aminoadipate aminotransferase

increases methylation

EXP

furan results in increased methylation of AADAT gene

NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540

G

alanine and arginine rich domain containing protein

increases expression

EXP

furan results in increased expression of AARD mRNA

NCBI chr 7:85,254,322...85,259,163
Ensembl chr 7:85,253,992...85,259,163

G

aminoadipate-semialdehyde synthase

decreases expression

EXP

furan results in decreased expression of AASS mRNA

NCBI chr 4:52,572,146...52,628,811
Ensembl chr 4:52,572,147...52,657,600

G

4-aminobutyrate aminotransferase

increases methylation

EXP

furan results in increased methylation of ABAT gene

NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474

G

ATP binding cassette subfamily A member 1

increases methylation

EXP

furan results in increased methylation of ABCA1 gene

NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473

G

ATP binding cassette subfamily A member 4

increases expression

EXP

furan results in increased expression of ABCA4 mRNA

NCBI chr 2:212,849,470...212,986,730
Ensembl chr 2:212,755,803...212,986,729

G

ATP binding cassette subfamily A member 5

increases expression

EXP

furan results in increased expression of ABCA5 mRNA

NCBI chr10:95,739,610...95,808,633
Ensembl chr10:95,739,610...95,808,424

G

ATP binding cassette subfamily A member 6

decreases expression

EXP

furan results in decreased expression of ABCA6 mRNA

NCBI chr10:95,642,026...95,711,535
Ensembl chr10:95,641,900...95,710,899

G

ATP binding cassette subfamily B member 11

decreases expression
multiple interactions

EXP
ISO

furan results in decreased expression of ABCB11 mRNA
[furan co-treated with rhodioloside] results in increased expression of ABCB11 mRNA

PMID:15120968 PMID:32251705

NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581

G

ATP-binding cassette, sub-family B member 1B

increases expression

EXP

furan results in increased expression of ABCB1B mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567

G

ATP binding cassette subfamily B member 4

increases expression

EXP

furan results in increased expression of ABCB4 mRNA

NCBI chr 4:26,106,895...26,164,440

G

ATP binding cassette subfamily C member 12

increases methylation

EXP

furan results in increased methylation of ABCC12 gene

NCBI chr19:36,722,550...36,798,868
Ensembl chr19:36,722,575...36,793,993

G

ATP binding cassette subfamily C member 2

increases expression

EXP

furan results in increased expression of ABCC2 mRNA

NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471

G

ATP binding cassette subfamily C member 3

increases expression

EXP

furan results in increased expression of ABCC3 mRNA

NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494

G

ATP binding cassette subfamily C member 4

increases expression

EXP

furan results in increased expression of ABCC4 mRNA

NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375

G

ATP binding cassette subfamily C member 5

increases expression

EXP

furan results in increased expression of ABCC5 mRNA

NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655

G

ATP binding cassette subfamily C member 6

decreases expression

EXP

furan results in decreased expression of ABCC6 mRNA

NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895

G

ATP binding cassette subfamily C member 8

decreases expression

EXP

furan results in decreased expression of ABCC8 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982

G

ATP binding cassette subfamily D member 2

increases expression

EXP

furan results in increased expression of ABCD2 mRNA

NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:124,142,595...124,191,202

G

ATP binding cassette subfamily D member 3

increases methylation

EXP

furan results in increased methylation of ABCD3 gene

NCBI chr 2:212,536,791...212,590,379
Ensembl chr 2:212,536,791...212,590,504

G

ATP binding cassette subfamily G member 2

increases expression

EXP

furan results in increased expression of ABCG2 mRNA

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

ATP-binding cassette, subfamily G (WHITE), member 3

decreases expression

EXP

furan results in decreased expression of ABCG3 mRNA

NCBI chr14:5,068,275...5,143,762
Ensembl chr14:5,086,356...5,143,945

G

ATP-binding cassette, subfamily G (WHITE), member 3-like 3

increases expression

EXP

furan results in increased expression of ABCG3L3 mRNA

NCBI chr14:5,148,826...5,196,890
Ensembl chr14:5,162,358...5,196,884

G

ATP binding cassette subfamily G member 5

increases expression

EXP

furan results in increased expression of ABCG5 mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376

G

abhydrolase domain containing 1

decreases methylation

EXP

furan results in decreased methylation of ABHD1 gene

NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464

G

abhydrolase domain containing 14b

decreases expression

EXP

furan results in decreased expression of ABHD14B mRNA

NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression
decreases expression

ISO
EXP

furan results in increased expression of ABHD2 mRNA
furan results in decreased expression of ABHD2 mRNA

PMID:24183702 PMID:25539665

NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674

G

abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

increases expression

ISO

furan results in increased expression of ABHD5 mRNA

NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947

G

actin binding LIM protein family, member 3

increases expression

EXP

furan results in increased expression of ABLIM3 mRNA

NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

increases expression

EXP

furan results in increased expression of ABO mRNA

NCBI chr 3:30,560,172...30,604,758

G

ankyrin repeat and BTB domain containing 1

increases methylation

EXP

furan results in increased methylation of ABTB1 gene

NCBI chr 4:122,856,558...122,862,895
Ensembl chr 4:122,856,564...122,862,789

G

acetyl-CoA acyltransferase 1A

decreases expression

EXP

furan results in decreased expression of ACAA1 mRNA

NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241

G

acetyl-CoA acyltransferase 2

affects binding

EXP

furan binds to ACAA2 protein

NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420

G

acetyl-CoA carboxylase alpha

decreases expression

EXP

furan results in decreased expression of ACACA mRNA

NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888

G

acetyl-CoA carboxylase beta

decreases expression

ISO

furan results in decreased expression of ACACB mRNA

NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214

G

acyl-CoA dehydrogenase family, member 10

decreases expression

EXP

furan results in decreased expression of ACAD10 mRNA

NCBI chr12:40,561,900...40,604,378
Ensembl chr12:40,566,701...40,604,378

G

acyl-CoA dehydrogenase, long chain

affects binding

EXP

furan binds to ACADL protein

NCBI chr 9:75,783,689...75,822,077
Ensembl chr 9:75,783,689...75,822,164

G

acyl-CoA dehydrogenase short chain

affects binding
decreases expression

EXP

furan binds to ACADS protein
furan results in decreased expression of ACADS mRNA

PMID:22240984 PMID:26194646

NCBI chr12:47,154,259...47,163,580
Ensembl chr12:47,154,276...47,164,103

G

acyl-CoA dehydrogenase, very long chain

decreases methylation

EXP

furan results in decreased methylation of ACADVL gene

NCBI chr10:55,231,558...55,236,786
Ensembl chr10:55,231,440...55,236,750

G

acetyl-CoA acetyltransferase 1

affects binding

EXP

furan binds to ACAT1 protein

NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042

G

ACD, shelterin complex subunit and telomerase recruitment factor

increases methylation

EXP

furan results in increased methylation of ACD gene

NCBI chr19:50,496,634...50,499,397
Ensembl chr19:50,496,635...50,499,326

G

angiotensin I converting enzyme

increases expression

EXP

furan results in increased expression of ACE mRNA

NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942

G

alkaline ceramidase 2

increases expression

EXP

furan results in increased expression of ACER2 mRNA

NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:106,437,796...106,488,583

G

alkaline ceramidase 3

increases expression

EXP

furan results in increased expression of ACER3 mRNA

NCBI chr 1:161,915,397...162,017,802
Ensembl chr 1:161,915,397...162,017,912

G

atypical chemokine receptor 2

increases methylation

EXP

furan results in increased methylation of ACKR2 gene

NCBI chr 8:130,438,703...130,451,106
Ensembl chr 8:130,384,559...130,464,393

G

atypical chemokine receptor 3

increases expression

EXP

furan results in increased expression of CXCR7 mRNA

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

ATP citrate lyase

decreases expression

EXP

furan results in decreased expression of ACLY mRNA

NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631

G

aminocarboxymuconate semialdehyde decarboxylase

increases expression

ISO
EXP

furan results in increased expression of ACMSD mRNA

PMID:24183702 PMID:26194646

NCBI chr13:41,752,894...41,798,427
Ensembl chr13:41,752,875...41,798,427

G

acyl-coenzyme A amino acid N-acyltransferase 2

decreases expression

EXP

furan results in decreased expression of ACNAT2 mRNA

NCBI chr 5:68,548,767...68,553,019
Ensembl chr 5:68,548,768...68,553,019

G

aconitase 1

increases methylation

EXP

furan results in increased methylation of ACO1 gene

NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600

G

acyl-CoA thioesterase 1

increases expression

EXP

furan results in increased expression of ACOT1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749

G

acyl-CoA thioesterase 12

increases methylation

EXP

furan results in increased methylation of ACOT12 gene

NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298

G

acyl-CoA thioesterase 2

increases expression

EXP

furan results in increased expression of ACOT2 mRNA

NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502

G

acyl-CoA thioesterase 4

increases methylation

EXP

furan results in increased methylation of ACOT4 gene

NCBI chr 6:109,399,032...109,405,138
Ensembl chr 6:109,399,578...109,405,138

G

acyl-CoA thioesterase 9

increases expression

EXP

furan results in increased expression of ACOT9 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205

G

acyl-CoA oxidase 1

increases methylation

EXP

furan results in increased methylation of ACOX1 gene

NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136

G

acid phosphatase 5, tartrate resistant

increases expression

EXP

furan results in increased expression of ACP5 mRNA

NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929

G

acrosin binding protein

increases methylation

EXP

furan results in increased methylation of ACRBP gene

NCBI chr 4:159,537,395...159,550,454
Ensembl chr 4:159,537,391...159,550,454

G

acyl-CoA synthetase long-chain family member 1

increases methylation
affects binding
decreases expression

EXP

furan results in increased methylation of ACSL1 gene
furan binds to ACSL1 protein
furan results in decreased expression of ACSL1 mRNA

PMID:22079235 PMID:22240984 PMID:26194646

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023

G

acyl-CoA synthetase medium-chain family member 3

increases methylation

EXP

furan results in increased methylation of ACSM3 gene

NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437

G

actin, alpha 1, skeletal muscle

increases expression

EXP

furan results in increased expression of ACTA1 mRNA

NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178

G

actin, beta

increases expression

EXP

furan results in increased expression of ACTB mRNA

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242

G

actin, alpha, cardiac muscle 1

increases methylation

EXP

furan results in increased methylation of ACTC1 gene

NCBI chr 3:121,266,291...121,271,827
Ensembl chr 3:121,266,291...121,271,827

G

actin-like 7b

decreases expression

EXP

furan results in decreased expression of ACTL7B mRNA

NCBI chr 5:76,240,739...76,242,127
Ensembl chr 5:76,240,742...76,242,176

G

actin-like 9b

increases methylation

EXP

furan results in increased methylation of ACTL9B gene

NCBI chr 1:72,745,456...72,746,793
Ensembl chr 1:72,744,303...72,746,873

G

actinin alpha 3

increases expression

EXP

furan results in increased expression of ACTN3 mRNA

NCBI chr 1:211,588,473...211,604,401
Ensembl chr 1:211,588,474...211,604,401

G

actin related protein 6

decreases methylation

EXP

furan results in decreased methylation of ACTR6 gene

NCBI chr 7:26,037,574...26,058,362
Ensembl chr 7:26,037,574...26,060,604

G

activin A receptor type 1

increases methylation

EXP

furan results in increased methylation of ACVR1 gene

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:63,387,381...63,477,884

G

activin A receptor type 1C

decreases expression

EXP

furan results in decreased expression of ACVR1C mRNA

NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:63,227,559...63,301,205

G

activin A receptor like type 1

increases expression

EXP

furan results in increased expression of ACVRL1 mRNA

NCBI chr 7:134,117,917...134,135,306
Ensembl chr 7:134,118,024...134,135,305

G

ADAM metallopeptidase domain 11

decreases expression

ISO

furan results in decreased expression of ADAM11 mRNA

NCBI chr10:88,224,185...88,242,865
Ensembl chr10:88,224,347...88,242,864

G

ADAM metallopeptidase domain 19

increases expression

EXP

furan results in increased expression of ADAM19 mRNA

NCBI chr10:30,992,713...31,084,455
Ensembl chr10:30,992,754...31,084,455

G

ADAM metallopeptidase domain 23

increases methylation

EXP

furan results in increased methylation of ADAM23 gene

NCBI chr 9:72,356,479...72,503,545
Ensembl chr 9:72,356,479...72,503,545

G

ADAM metallopeptidase domain 28

increases expression

EXP

furan results in increased expression of ADAM28 mRNA

NCBI chr15:50,184,286...50,250,605
Ensembl chr15:50,127,516...50,250,526

G

ADAM metallopeptidase domain 32

increases expression

ISO

furan results in increased expression of ADAM32 mRNA

NCBI chr16:73,805,023...73,914,787
Ensembl chr16:73,805,052...73,914,785

G

a disintegrin and metalloprotease domain 4

increases expression

EXP

furan results in increased expression of ADAM4 mRNA

NCBI chr 6:106,854,533...106,856,979

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases expression
decreases methylation

ISO
EXP

furan results in increased expression of ADAMTS1 mRNA
furan results in decreased methylation of ADAMTS1 gene

PMID:24183702 PMID:27387713

NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

increases expression

EXP

furan results in increased expression of ADAMTS15 mRNA

NCBI chr 8:37,566,064...37,589,446
Ensembl chr 8:37,566,065...37,589,446

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of ADAMTS2 gene
furan results in increased expression of ADAMTS2 mRNA

NCBI chr10:35,422,030...35,627,483
Ensembl chr10:35,422,030...35,627,483

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

increases expression

EXP

furan results in increased expression of ADAMTS5 mRNA

NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516

G

ADAM metallopeptidase with thrombospondin type 1 motif, 9

increases methylation
increases expression

EXP

furan results in increased methylation of ADAMTS9 gene
furan results in increased expression of ADAMTS9 mRNA

PMID:22079235 PMID:27387713

NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876

G

ADAMTS-like 2

increases expression

EXP

furan results in increased expression of ADAMTSL2 mRNA

NCBI chr 3:30,795,882...30,832,635
Ensembl chr 3:30,802,700...30,832,635

G

ArfGAP with dual PH domains 2

decreases expression

EXP

furan results in decreased expression of ADAP2 mRNA

NCBI chr10:65,635,891...65,665,019
Ensembl chr10:65,622,434...65,664,022

G

adenylate cyclase 6

increases methylation

EXP

furan results in increased methylation of ADCY6 gene

NCBI chr 7:131,621,860...131,642,923
Ensembl chr 7:131,621,860...131,642,770

G

adenylate cyclase activating polypeptide 1

decreases expression
increases expression

EXP

furan results in decreased expression of ADCYAP1 mRNA
furan results in increased expression of ADCYAP1 mRNA

NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383

G

ADCYAP receptor type I

decreases expression

EXP

furan results in decreased expression of ADCYAP1R1 mRNA

NCBI chr 4:85,924,171...85,972,973
Ensembl chr 4:85,924,100...85,972,973

G

adducin 3

increases expression

EXP

furan results in increased expression of ADD3 mRNA

NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504

G

adhesion G protein-coupled receptor G2

increases expression

EXP

furan results in increased expression of ADGRG2 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:38,106,067...38,231,286
Ensembl chr X:38,106,067...38,231,331

G

adhesion G protein-coupled receptor G7

decreases methylation
increases expression

EXP

furan results in decreased methylation of ADGRG7 gene
furan results in increased expression of ADGRG7 mRNA

PMID:22079235 PMID:27387713

NCBI chr11:57,282,904...57,345,417
Ensembl chr11:57,282,904...57,345,417

G

adhesion G protein-coupled receptor L2

increases methylation

EXP

furan results in increased methylation of ADGRL2 gene

NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933

G

alcohol dehydrogenase 4 (class II), pi polypeptide

increases expression

EXP

furan results in increased expression of ADH4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

increases methylation

EXP

furan results in increased methylation of ADH7 gene

NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691

G

acireductone dioxygenase 1

decreases expression

EXP

furan results in decreased expression of ADI1 mRNA

NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855

G

adiponectin, C1Q and collagen domain containing

increases expression

EXP

furan results in increased expression of ADIPOQ mRNA

NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169

G

adiponectin receptor 1

increases methylation

EXP

furan results in increased methylation of ADIPOR1 gene

NCBI chr13:48,411,438...48,431,251
Ensembl chr13:48,411,826...48,431,255

G

adrenomedullin

increases expression

EXP

furan results in increased expression of ADM mRNA

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371

G

adenosine A1 receptor

increases expression

EXP

furan results in increased expression of ADORA1 mRNA

NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190

G

adenosine A2B receptor

increases expression

EXP

furan results in increased expression of ADORA2B mRNA

NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091

G

adrenoceptor alpha 1D

increases expression

EXP

furan results in increased expression of ADRA1D mRNA

NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331

G

adrenoceptor beta 2

increases methylation

EXP

furan results in increased methylation of ADRB2 gene

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

adrenoceptor beta 3

decreases expression

ISO

furan results in decreased expression of ADRB3 mRNA

NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420

G

androgen-dependent TFPI-regulating protein

increases methylation

EXP

furan results in increased methylation of ADTRP gene

NCBI chr17:23,113,578...23,199,616
Ensembl chr17:23,135,809...23,216,622

G

AE binding protein 1

increases expression

EXP

furan results in increased expression of AEBP1 mRNA

NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843

G

AE binding protein 2

increases expression

ISO

furan results in increased expression of AEBP2 mRNA

NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422

G

apoptosis enhancing nuclease

increases expression

ISO

furan results in increased expression of AEN mRNA

PMID:24183702 PMID:37517673

NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898

G

alpha-fetoprotein

increases expression

ISO
EXP

furan results in increased expression of AFP mRNA

PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649

G

advanced glycosylation end product-specific receptor

increases methylation

EXP

furan results in increased methylation of AGER gene

NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685

G

ArfGAP with FG repeats 1

increases methylation

EXP

furan results in increased methylation of AGFG1 gene

NCBI chr 9:91,572,962...91,630,688
Ensembl chr 9:91,573,157...91,626,910

G

ArfGAP with FG repeats 2

increases methylation

EXP

furan results in increased methylation of AGFG2 gene

NCBI chr12:24,649,008...24,692,069
Ensembl chr12:24,649,038...24,685,197

G

agmatinase

increases methylation

EXP

furan results in increased methylation of AGMAT gene

NCBI chr 5:159,326,680...159,357,300
Ensembl chr 5:159,343,160...159,357,299

G

1-acylglycerol-3-phosphate O-acyltransferase 4

increases expression

EXP

furan results in increased expression of AGPAT4 mRNA

NCBI chr 1:51,075,081...51,181,548
Ensembl chr 1:51,075,081...51,180,976

G

alkylglycerone phosphate synthase

increases expression

EXP

furan results in increased expression of AGPS mRNA

NCBI chr 3:81,154,599...81,253,099
Ensembl chr 3:81,154,604...81,258,277

G

anterior gradient 2, protein disulphide isomerase family member

increases expression

EXP

furan results in increased expression of AGR2 mRNA

NCBI chr 6:58,435,908...58,456,678
Ensembl chr 6:58,435,908...58,456,677

G

anterior gradient 3, protein disulphide isomerase family member

increases expression

EXP

furan results in increased expression of AGR3 mRNA

NCBI chr 6:58,370,701...58,393,944
Ensembl chr 6:58,370,701...58,399,859

G

angiotensinogen

decreases expression

EXP

furan results in decreased expression of AGT mRNA

PMID:25539665 PMID:26194646

NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944

G

alanine--glyoxylate aminotransferase

increases methylation
decreases expression

EXP

furan results in increased methylation of AGXT gene
furan results in decreased expression of AGXT mRNA

PMID:22079235 PMID:25539665

NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:101,122,793...101,132,745

G

AHNAK nucleoprotein

decreases expression
decreases methylation
increases expression

ISO
EXP

furan results in decreased expression of AHNAK mRNA
furan results in decreased methylation of AHNAK gene
furan results in increased expression of AHNAK mRNA

PMID:24183702 PMID:27387713

NCBI chr 1:215,311,289...215,400,010
Ensembl chr 1:215,321,931...215,400,675

G

aryl-hydrocarbon receptor repressor

increases methylation

EXP

furan results in increased methylation of AHRR gene

NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866

G

AIF family member 3

decreases expression

ISO

furan results in decreased expression of AIFM3 mRNA

PMID:24183702 PMID:37517673

NCBI chr11:97,009,100...97,030,601
Ensembl chr11:97,008,426...97,023,334

G

ajuba LIM protein

increases expression

EXP

furan results in increased expression of AJUBA mRNA; furan results in increased expression of JUB mRNA

PMID:25539665 PMID:26194646

NCBI chr15:31,989,796...32,000,042
Ensembl chr15:31,989,799...32,000,042

G

adenylate kinase 1

increases expression

EXP

furan results in increased expression of AK1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757

G

A-kinase anchoring protein 5

decreases expression

EXP

furan results in decreased expression of AKAP5 mRNA

NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620

G

AKNA domain containing 1

decreases expression

EXP

furan results in decreased expression of AKNAD1 mRNA

NCBI chr 2:199,076,864...199,120,402
Ensembl chr 2:199,081,596...199,120,375

G

alkaline phosphatase 3, intestine, not Mn requiring

increases methylation

EXP

furan results in increased methylation of AKP3 gene

NCBI chr 9:95,252,581...95,256,616
Ensembl chr 9:95,248,840...95,256,616

G

aldo-keto reductase family 1 member A1

increases expression

EXP

furan results in increased expression of AKR1A1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035

G

aldo-keto reductase family 1 member B10

increases expression

EXP

furan results in increased expression of AKR1B10 mRNA

NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847

G

aldo-keto reductase family 1 member B15

increases expression

EXP

furan results in increased expression of AKR1B8 mRNA

NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349

G

aldo-keto reductase family 1, member B7

increases methylation
increases expression

EXP

furan results in increased methylation of AKR1B7 gene
furan results in increased expression of AKR1B7 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 4:64,043,901...64,083,751
Ensembl chr 4:64,020,686...64,064,909

G

aldo-keto reductase family 1, member C1

decreases expression

EXP

furan results in decreased expression of AKR1C1 mRNA

NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247

G

aldo-keto reductase family 1, member C12

increases expression

EXP

furan results in increased expression of AKR1C12 mRNA

PMID:25539665 PMID:26194646

NCBI chr17:70,955,288...70,971,412
Ensembl chr17:70,955,294...70,971,431

G

aldo-keto reductase family 1, member C13

decreases expression

EXP

furan results in decreased expression of AKR1C13 mRNA

NCBI chr17:70,874,110...70,907,518
Ensembl chr17:70,874,917...70,907,824

G

aldo-keto reductase family 1, member C14

affects binding

EXP

furan binds to AKR1C14 protein

NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157

G

aldo-keto reductase family 1, member C19

increases expression

EXP

furan results in increased expression of AKR1C19 mRNA

NCBI chr17:70,913,916...70,934,959
Ensembl chr17:70,919,236...70,934,959

G

aldo-keto reductase family 1, member C3

increases expression

ISO

furan results in increased expression of AKR1C18 mRNA

PMID:24183702 PMID:37517673

NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438

G

aldo-keto reductase family 7, member A2

affects binding

EXP

furan binds to AKR7A2 protein

NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109

G

aldo-keto reductase family 7 member A3

increases methylation
increases expression

EXP

furan results in increased methylation of AKR7A3 gene
furan results in increased expression of AKR7A3 mRNA

PMID:15120968 PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153

G

AKT interacting protein

increases methylation

EXP

furan results in increased methylation of AKTIP gene

NCBI chr19:32,039,507...32,059,634
Ensembl chr19:32,039,466...32,067,178

G

aminolevulinate dehydratase

affects binding

EXP

furan binds to ALAD protein

NCBI chr 5:80,977,562...80,987,901
Ensembl chr 5:80,977,562...80,988,041

G

albumin

decreases expression
increases methylation

EXP

furan results in decreased expression of ALB mRNA
furan results in increased methylation of ALB gene

PMID:15120968 PMID:22079235

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldehyde dehydrogenase 16 family, member A1

decreases methylation

EXP

furan results in decreased methylation of ALDH16A1 gene

NCBI chr 1:104,763,200...104,776,270
Ensembl chr 1:104,763,055...104,776,270

G

aldehyde dehydrogenase 18 family, member A1

increases expression

EXP

furan results in increased expression of ALDH18A1 mRNA

NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383

G

aldehyde dehydrogenase 1 family, member A1

increases expression

EXP

furan results in increased expression of ALDH1A1 mRNA

NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500

G

aldehyde dehydrogenase 1 family, member A2

increases methylation
decreases methylation
increases expression

EXP

furan results in increased methylation of ALDH1A2 gene
furan results in decreased methylation of ALDH1A2 gene
furan results in increased expression of ALDH1A2 mRNA

PMID:22079235 PMID:27387713

NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883

G

aldehyde dehydrogenase 1 family, member A3

increases expression

EXP

furan results in increased expression of ALDH1A3 mRNA

NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:129,392,516...129,427,777

G

aldehyde dehydrogenase family 1, subfamily A7

increases expression

EXP

furan results in increased expression of ALDH1A7 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523

G

aldehyde dehydrogenase 1 family, member B1

increases methylation
increases expression

EXP

furan results in increased methylation of ALDH1B1 gene
furan results in increased expression of ALDH1B1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365

G

aldehyde dehydrogenase 2 family member

affects binding
decreases expression

EXP

furan binds to ALDH2 protein
furan results in decreased expression of ALDH2 mRNA

PMID:22240984 PMID:25539665 PMID:26194646

NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219

G

aldehyde dehydrogenase 3 family, member B1

increases expression

EXP

furan results in increased expression of ALDH3B1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:210,574,545...210,605,188
Ensembl chr 1:210,573,661...210,610,538

G

aldehyde dehydrogenase 4 family, member A1

increases expression

EXP

furan results in increased expression of ALDH4A1 mRNA

NCBI chr 5:157,163,189...157,188,673
Ensembl chr 5:157,162,945...157,188,673

G

aldehyde dehydrogenase 7 family, member A1

decreases expression

EXP

furan results in decreased expression of ALDH7A1 mRNA

NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467

G

aldolase, fructose-bisphosphate A

increases expression

EXP

furan results in increased expression of ALDOA mRNA

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

aldolase 1 A retrogene 2

increases expression

EXP

furan results in increased expression of ALDOART2 mRNA

NCBI chr 6:78,674,945...78,676,635
Ensembl chr 6:78,673,353...78,680,406

G

aldolase, fructose-bisphosphate B

affects binding
increases methylation

EXP

furan binds to ALDOB protein
furan results in increased methylation of ALDOB gene

PMID:22079235 PMID:22240984

NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740

G

aldolase, fructose-bisphosphate C

increases expression

EXP

furan results in increased expression of ALDOC mRNA

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133

G

ALG14, UDP-N-acetylglucosaminyltransferase subunit

increases methylation

EXP

furan results in increased methylation of ALG14 gene

NCBI chr 2:212,053,008...212,130,136
Ensembl chr 2:212,044,969...212,130,140

G

arachidonate 5-lipoxygenase

increases expression

EXP

furan results in increased expression of ALOX5 mRNA

NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126

G

arachidonate 5-lipoxygenase activating protein

increases methylation
increases expression

EXP

furan results in increased methylation of ALOX5AP gene
furan results in increased expression of ALOX5AP mRNA

PMID:22079235 PMID:27387713

NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038

G

arachidonate epidermal lipoxygenase 3

increases expression

EXP

furan results in increased expression of ALOXE3 mRNA

NCBI chr10:54,329,224...54,353,167
Ensembl chr10:54,329,043...54,353,166

G

alpha-kinase 3

decreases expression

EXP

furan results in decreased expression of ALPK3 mRNA

NCBI chr 1:144,423,690...144,471,534
Ensembl chr 1:144,423,726...144,490,309

G

alkaline phosphatase, biomineralization associated

increases expression

EXP

furan results in increased expression of ALPL mRNA; furan results in increased expression of ALPL protein

PMID:25539665 PMID:26194646 PMID:38160780

NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167

G

ALX homeobox 3

decreases expression

EXP

furan results in decreased expression of ALX3 mRNA

NCBI chr 2:197,919,381...197,929,795
Ensembl chr 2:197,919,381...197,929,795

G

alpha-methylacyl-CoA racemase

decreases expression

EXP

furan results in decreased expression of AMACR mRNA

NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379

G

alpha-1-microglobulin/bikunin precursor

affects binding
decreases expression

EXP

furan binds to AMBP protein
furan results in decreased expression of AMBP mRNA

PMID:15120968 PMID:22240984 PMID:26194646

NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850

G

anti-Mullerian hormone receptor type 2

increases expression

EXP

furan results in increased expression of AMHR2 mRNA

NCBI chr 7:135,454,517...135,470,183
Ensembl chr 7:135,457,922...135,471,104

G

amnion associated transmembrane protein

increases expression

ISO
EXP

furan results in increased expression of AMN mRNA

PMID:24183702 PMID:25539665

NCBI chr 6:136,132,567...136,140,008
Ensembl chr 6:136,132,567...136,140,008

G

adenosine monophosphate deaminase 1

decreases methylation

EXP

furan results in decreased methylation of AMPD1 gene

NCBI chr 2:193,287,219...193,308,446
Ensembl chr 2:193,287,265...193,308,443

G

adenosine monophosphate deaminase 2

increases expression

EXP

furan results in increased expression of AMPD2 mRNA

NCBI chr 2:198,395,767...198,408,514
Ensembl chr 2:198,395,768...198,408,796

G

adenosine monophosphate deaminase 3

increases expression

EXP

furan results in increased expression of AMPD3 mRNA

NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608

G

angiogenin

decreases expression

EXP

furan results in decreased expression of ANG mRNA

PMID:25539665 PMID:26194646

NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106

G

angiopoietin 1

increases expression

EXP

furan results in increased expression of ANGPT1 mRNA

NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696

G

angiopoietin-like 4

decreases expression

EXP

furan results in decreased expression of ANGPTL4 mRNA

NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681

G

ankyrin 3

increases methylation

EXP

furan results in increased methylation of ANK3 gene

NCBI chr20:18,601,307...19,224,790
Ensembl chr20:18,601,826...19,084,879

G

ankyrin repeat domain 10

increases expression

EXP

furan results in increased expression of ANKRD10 mRNA

NCBI chr16:84,566,021...84,591,849
Ensembl chr16:84,568,506...84,591,846

G

ankyrin repeat domain 13B

increases expression

EXP

furan results in increased expression of ANKRD13B mRNA

NCBI chr10:62,817,791...62,836,456
Ensembl chr10:62,817,778...62,836,635

G

ankyrin repeat domain 13D

increases expression

EXP

furan results in increased expression of ANKRD13D mRNA

NCBI chr 1:210,995,012...211,007,430
Ensembl chr 1:210,995,148...211,007,369

G

ankyrin repeat domain 22

increases expression

EXP

furan results in increased expression of ANKRD22 mRNA

NCBI chr 1:241,052,235...241,083,737
Ensembl chr 1:241,052,237...241,105,559

G

ankyrin repeat domain 33

decreases expression

EXP

furan results in decreased expression of ANKRD33 mRNA

NCBI chr 7:134,102,906...134,106,860
Ensembl chr 7:134,103,811...134,106,566

G

ankyrin repeat domain 34A

increases expression

EXP

furan results in increased expression of ANKRD34A mRNA

NCBI chr 2:186,818,496...186,823,921
Ensembl chr 2:186,817,216...186,824,467

G

ankyrin repeat and sterile alpha motif domain containing 4B

decreases expression

EXP

furan results in decreased expression of ANKS4B mRNA

NCBI chr 1:183,934,528...183,989,127
Ensembl chr 1:183,978,769...183,989,122

G

anoctamin 1

increases expression

EXP

furan results in increased expression of ANO1 mRNA

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

anoctamin 4

increases methylation

EXP

furan results in increased methylation of ANO4 gene

NCBI chr 7:25,216,389...25,625,811
Ensembl chr 7:25,216,389...25,625,746

G

alanyl aminopeptidase, membrane

increases methylation
increases expression

EXP

furan results in increased methylation of ANPEP gene
furan results in increased expression of ANPEP mRNA

PMID:22079235 PMID:26194646

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

ANTXR cell adhesion molecule 1

increases expression

EXP

furan results in increased expression of ANTXR1 mRNA

PMID:25539665 PMID:27387713

NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892

G

annexin A1

increases expression

EXP

furan results in increased expression of ANXA1 mRNA

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A10

increases expression

EXP

furan results in increased expression of ANXA10 mRNA

NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961

G

annexin A11

increases methylation

EXP

furan results in increased methylation of ANXA11 gene

NCBI chr16:1,419,627...1,464,590
Ensembl chr16:1,418,351...1,464,839

G

annexin A13

increases expression

EXP

furan results in increased expression of ANXA13 mRNA

NCBI chr 7:91,773,844...91,826,386
Ensembl chr 7:91,770,861...91,826,386

G

annexin A2

increases expression

EXP

furan results in increased expression of ANXA2 mRNA

PMID:15120968 PMID:20124500 PMID:26194646 PMID:27387713

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A4

increases expression

EXP

furan results in increased expression of ANXA4 mRNA

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513

G

annexin A5

increases expression
decreases methylation

EXP

furan results in increased expression of ANXA5 mRNA
furan results in decreased methylation of ANXA5 gene

PMID:15120968 PMID:26194646 PMID:27387713

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

annexin A7

increases expression

EXP

furan results in increased expression of ANXA7 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891

G

annexin A9

increases expression

EXP

furan results in increased expression of ANXA9 mRNA

NCBI chr 2:185,562,174...185,572,560
Ensembl chr 2:185,562,174...185,572,560

G

amine oxidase, copper containing 3

increases expression

EXP

furan results in increased expression of AOC3 mRNA

NCBI chr10:86,773,018...86,780,961

G

aldehyde oxidase 3

decreases expression
increases methylation

EXP

furan results in decreased expression of AOX3 mRNA
furan results in increased methylation of AOX3 gene

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 9:67,158,987...67,245,299
Ensembl chr 9:67,159,000...67,244,013

G

adaptor related protein complex 1 subunit mu 2

increases expression

EXP

furan results in increased expression of AP1M2 mRNA

NCBI chr 8:28,114,748...28,132,767
Ensembl chr 8:28,114,748...28,132,642

G

adaptor related protein complex 1 subunit sigma 2

increases methylation
increases expression

EXP

furan results in increased methylation of AP1S2 gene
furan results in increased expression of AP1S2 mRNA

PMID:22079235 PMID:27387713

NCBI chr X:34,204,601...34,230,819
Ensembl chr X:34,204,603...34,228,529

G

adaptor related protein complex 3 subunit mu 1

increases methylation

EXP

furan results in increased methylation of AP3M1 gene

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,295,444...3,313,104

G

apoptotic peptidase activating factor 1

increases expression

EXP

furan results in increased expression of APAF1 mRNA

NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772

G

amyloid beta precursor protein binding family B member 1

increases expression

EXP

furan results in increased expression of APBB1 mRNA

NCBI chr 1:169,308,719...169,332,372
Ensembl chr 1:169,308,720...169,332,552

G

amyloid P component, serum

decreases expression

EXP

furan results in decreased expression of APCS mRNA

NCBI chr13:87,905,532...87,906,508
Ensembl chr13:87,905,532...87,928,824

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression

EXP

furan results in increased expression of APEX1 mRNA

PMID:22079235 PMID:25539665

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

aph-1 homolog B, gamma secretase subunit

increases expression

EXP

furan results in increased expression of APH1B mRNA

NCBI chr 8:76,310,380...76,334,146
Ensembl chr 8:76,310,380...76,331,428

G

aprataxin and PNKP like factor

increases expression

EXP

furan results in increased expression of APLF mRNA

NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961

G

adipocyte plasma membrane associated protein

increases methylation

EXP

furan results in increased methylation of APMAP gene

NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726

G

apolipoprotein A2

decreases expression
increases methylation

EXP

furan results in decreased expression of APOA2 mRNA
furan results in increased methylation of APOA2 gene

PMID:15120968 PMID:22079235

NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410

G

apolipoprotein A4

decreases expression

EXP

furan results in decreased expression of APOA4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164

G

apolipoprotein A5

increases methylation
decreases expression

EXP

furan results in increased methylation of APOA5 gene
furan results in decreased expression of APOA5 mRNA

PMID:22079235 PMID:25539665

NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507

G

apolipoprotein B mRNA editing enzyme catalytic subunit 2

increases expression

EXP

furan results in increased expression of APOBEC2 mRNA

NCBI chr 9:20,062,561...20,076,074
Ensembl chr 9:20,062,526...20,076,071

G

apolipoprotein C1

decreases expression

EXP

furan results in decreased expression of APOC1 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155

G

apolipoprotein C2

increases methylation
decreases expression

EXP

furan results in increased methylation of APOC2 gene
furan results in decreased expression of APOC2 mRNA

PMID:22079235 PMID:26194646

NCBI chr 1:88,457,397...88,462,365
Ensembl chr 1:88,457,396...88,463,438

G

apolipoprotein C3

decreases expression

EXP

furan results in decreased expression of APOC3 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 8:55,428,172...55,430,352
Ensembl chr 8:55,428,024...55,458,679

G

apolipoprotein C4

decreases expression

EXP

furan results in decreased expression of APOC4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:88,463,713...88,467,909
Ensembl chr 1:88,463,713...88,468,044

G

apolipoprotein D

increases methylation

EXP

furan results in increased methylation of APOD gene

NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263

G

apolipoprotein E

decreases expression

EXP

furan results in decreased expression of APOE mRNA

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

apolipoprotein F

increases methylation

EXP

furan results in increased methylation of APOF gene

NCBI chr 7:1,285,222...1,286,659
Ensembl chr 7:1,285,222...1,286,659

G

apolipoprotein L9a

decreases expression

EXP

furan results in decreased expression of APOL9A mRNA

NCBI chr 7:111,021,452...111,030,380
Ensembl chr 7:111,021,453...111,028,213

G

Apol9a-Apol7a readthrough

decreases expression

ISO

furan results in decreased expression of APOL7B mRNA

NCBI chr 7:111,011,645...111,019,326
Ensembl chr 7:111,011,645...111,017,084

G

apolipoprotein M

increases methylation
decreases expression

EXP

furan results in increased methylation of APOM gene
furan results in decreased expression of APOM mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218

G

apolipoprotein N

decreases expression

EXP

furan results in decreased expression of APON mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:1,271,514...1,272,917
Ensembl chr 7:1,271,515...1,272,917

G

amyloid beta precursor protein

increases expression

EXP

furan results in increased expression of APP mRNA

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

aquaporin 3 (Gill blood group)

increases expression
decreases expression

EXP

furan results in increased expression of AQP3 mRNA
furan results in decreased expression of AQP3 mRNA

PMID:25539665 PMID:27387713

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685

G

aquaporin 4

increases expression

EXP

furan results in increased expression of AQP4 mRNA

NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098

G

aquaporin 5

increases expression

EXP

furan results in increased expression of AQP5 mRNA

NCBI chr 7:132,601,528...132,605,060
Ensembl chr 7:132,601,059...132,605,062

G

aquaporin 7

increases expression

EXP

furan results in increased expression of AQP7 mRNA

NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618

G

aquaporin 8

increases methylation

EXP

furan results in increased methylation of AQP8 gene

NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242

G

androgen receptor

decreases expression

EXP

furan results in decreased expression of AR mRNA

PMID:25539665 PMID:26194646

NCBI chr X:67,135,317...67,304,476
Ensembl chr X:67,135,317...67,304,467

G

A-Raf proto-oncogene, serine/threonine kinase

increases methylation

EXP

furan results in increased methylation of ARAF gene

NCBI chr X:3,780,932...3,845,919
Ensembl chr X:3,780,932...3,792,611

G

activity-regulated cytoskeleton-associated protein

increases expression

EXP

furan results in increased expression of ARC mRNA

NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220

G

amphiregulin

decreases methylation
increases expression

EXP

furan results in decreased methylation of AREG gene
furan results in increased expression of AREG mRNA

NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641

G

ADP-ribosylation factor 2

increases expression

EXP

furan results in increased expression of ARF2 mRNA

NCBI chr10:89,367,843...89,389,644
Ensembl chr10:89,368,044...89,389,651

G

arginase 1

affects binding
decreases activity

EXP

furan binds to ARG1 protein
furan results in decreased activity of ARG1 protein

PMID:22240984 PMID:27402187

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

arginase 2

increases expression

EXP

furan results in increased expression of ARG2 mRNA

NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375

G

arginine and glutamate rich 1

increases methylation

EXP

furan results in increased methylation of ARGLU1 gene

NCBI chr16:87,455,097...87,479,148
Ensembl chr16:87,455,113...87,479,148

G

Rho GTPase activating protein 11A

increases expression

EXP

furan results in increased expression of ARHGAP11A mRNA

NCBI chr 3:121,045,187...121,071,985
Ensembl chr 3:121,045,187...121,061,468

G

Rho GTPase activating protein 18

increases expression

EXP

furan results in increased expression of ARHGAP18 mRNA

NCBI chr 1:20,222,948...20,456,827
Ensembl chr 1:20,222,954...20,456,670

G

Rho GTPase activating protein 20

increases expression

EXP

furan results in increased expression of ARHGAP20 mRNA

NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:60,970,475...61,055,198

G

Rho GTPase activating protein 22

increases expression

EXP

furan results in increased expression of ARHGAP22 mRNA

NCBI chr16:8,480,222...8,637,823
Ensembl chr16:8,479,956...8,637,822

G

Rho GTPase activating protein 28

increases expression

EXP

furan results in increased expression of ARHGAP28 mRNA

NCBI chr 9:115,277,849...115,444,789
Ensembl chr 9:115,279,734...115,445,008

G

Rho GDP dissociation inhibitor gamma

increases methylation

EXP

furan results in increased methylation of ARHGDIG gene

NCBI chr10:15,723,525...15,725,719
Ensembl chr10:15,723,525...15,725,688

G

Rho/Rac guanine nucleotide exchange factor 18

increases methylation

EXP

furan results in increased methylation of ARHGEF18 gene

NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997

G

Rho guanine nucleotide exchange factor 25

increases expression

EXP

furan results in increased expression of ARHGEF25 mRNA

NCBI chr 7:64,891,260...64,898,382
Ensembl chr 7:64,890,879...64,898,697

G

Rho guanine nucleotide exchange factor 26

multiple interactions

ISO

[Bromodeoxyuridine co-treated with furan] affects the expression of ARHGEF26 mRNA

NCBI chr 2:148,889,405...149,000,538
Ensembl chr 2:148,889,423...149,000,538

G

Rho guanine nucleotide exchange factor 28

increases expression

EXP

furan results in increased expression of ARHGEF28 mRNA

NCBI chr 2:30,998,292...31,294,757
Ensembl chr 2:30,998,295...31,294,853

G

Rho guanine nucleotide exchange factor 40

decreases expression

EXP

furan results in decreased expression of ARHGEF40 mRNA

NCBI chr15:27,146,155...27,170,012
Ensembl chr15:27,146,197...27,170,012

G

Cdc42 guanine nucleotide exchange factor 9

increases expression

EXP

furan results in increased expression of ARHGEF9 mRNA

NCBI chr X:63,929,168...64,087,267
Ensembl chr X:63,929,176...64,087,104

G

AT-rich interaction domain 1A

increases methylation

EXP

furan results in increased methylation of ARID1A gene

NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386

G

AT-rich interaction domain 1B

increases methylation

EXP

furan results in increased methylation of ARID1B gene

NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793

G

AT-rich interaction domain 4A

decreases expression

EXP

furan results in decreased expression of ARID4A mRNA

NCBI chr 6:95,258,429...95,335,987
Ensembl chr 6:95,258,429...95,329,840

G

arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C

decreases expression

EXP

furan results in decreased expression of ARK2C mRNA

NCBI chr18:73,259,736...73,375,987
Ensembl chr18:73,264,901...73,375,987

G

ARF like GTPase 11

increases expression

EXP

furan results in increased expression of ARL11 mRNA

PMID:25539665 PMID:27387713

NCBI chr15:39,659,404...39,661,651
Ensembl chr15:39,656,050...39,664,105

G

ARF like GTPase 2

increases methylation

EXP

furan results in increased methylation of ARL2 gene

NCBI chr 1:212,863,422...212,875,425
Ensembl chr 1:212,863,423...212,875,373

G

ARF like GTPase 4D

decreases expression

ISO

furan results in decreased expression of ARL4D mRNA

NCBI chr10:87,092,276...87,103,079
Ensembl chr10:87,077,523...87,106,199

G

ARF like GTPase 6

increases expression

EXP

furan results in increased expression of ARL6 mRNA

NCBI chr11:54,180,271...54,207,136
Ensembl chr11:54,181,241...54,210,813

G

ARF like GTPase 8B

increases expression

EXP

furan results in increased expression of ARL8B mRNA

NCBI chr 4:143,304,597...143,348,580
Ensembl chr 4:143,304,621...143,349,068

G

armadillo repeat containing, X-linked 1

increases methylation

EXP

furan results in increased methylation of ARMCX1 gene

NCBI chr X:102,192,225...102,196,130
Ensembl chr X:102,192,015...102,199,115

G

armadillo repeat containing, X-linked 2

increases expression

EXP

furan results in increased expression of ARMCX2 mRNA

NCBI chr X:102,273,915...102,278,789
Ensembl chr X:102,273,565...102,278,905

G

armadillo repeat containing, X-linked 3

increases methylation

EXP

furan results in increased methylation of ARMCX3 gene

NCBI chr X:102,230,464...102,234,017
Ensembl chr X:102,219,848...102,263,297

G

aryl hydrocarbon receptor nuclear translocator 2

increases methylation
increases expression

EXP

furan results in increased methylation of ARNT2 gene
furan results in increased expression of ARNT2 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:147,645,354...147,801,986
Ensembl chr 1:147,599,058...147,801,997

G

arrestin domain containing 4

increases methylation

EXP

furan results in increased methylation of ARRDC4 gene

NCBI chr 1:131,779,436...131,793,438
Ensembl chr 1:131,779,437...131,793,565

G

arylsulfatase family, member I

increases expression

EXP

furan results in increased expression of ARSI mRNA

NCBI chr18:56,634,556...56,642,168
Ensembl chr18:56,625,487...56,642,168

G

ADP-ribosyltransferase 2b

increases methylation

EXP

furan results in increased methylation of ART2B gene

NCBI chr 1:165,368,623...165,386,280
Ensembl chr 1:165,368,625...165,378,345

G

arsenite methyltransferase

decreases expression

EXP

furan results in decreased expression of AS3MT mRNA

NCBI chr 1:255,536,879...255,569,245
Ensembl chr 1:255,537,109...255,569,249

G

N-acylsphingosine amidohydrolase 2

increases expression

EXP

furan results in increased expression of ASAH2 mRNA

NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:239,278,994...239,382,024

G

ankyrin repeat and SOCS box-containing 10

increases methylation

EXP

furan results in increased methylation of ASB10 gene

NCBI chr 4:11,522,531...11,531,946
Ensembl chr 4:11,522,887...11,531,505

G

ankyrin repeat and SOCS box-containing 16

increases expression

EXP

furan results in increased expression of ASB16 mRNA

NCBI chr10:87,726,128...87,733,228
Ensembl chr10:87,726,056...87,735,059

G

ankyrin repeat and SOCS box-containing 4

increases methylation

EXP

furan results in increased methylation of ASB4 gene

NCBI chr 4:34,473,527...34,511,163
Ensembl chr 4:34,473,408...34,512,888

G

ankyrin repeat and SOCS box-containing 5

decreases methylation
increases expression

EXP

furan results in decreased methylation of ASB5 gene
furan results in increased expression of ASB5 mRNA

PMID:22079235 PMID:25539665

NCBI chr16:43,970,940...44,038,318
Ensembl chr16:43,970,940...44,010,437

G

ankyrin repeat and SOCS box-containing 7

increases methylation

EXP

furan results in increased methylation of ASB7 gene

NCBI chr 1:129,621,462...129,677,788
Ensembl chr 1:129,635,330...129,677,505

G

anti-silencing function 1B histone chaperone

increases expression

EXP

furan results in increased expression of ASF1B mRNA

NCBI chr19:41,085,786...41,100,352
Ensembl chr19:41,086,114...41,100,352

G

asialoglycoprotein receptor 1

increases methylation
decreases expression

EXP

furan results in increased methylation of ASGR1 gene
furan results in decreased expression of ASGR1 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322

G

asialoglycoprotein receptor 2

decreases expression

EXP

furan results in decreased expression of ASGR2 mRNA

NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263

G

acid sensing ion channel subunit 3

increases methylation

EXP

furan results in increased methylation of ASIC3 gene

NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:11,652,946...11,657,367

G

argininosuccinate lyase

increases methylation

EXP

furan results in increased methylation of ASL gene

NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261

G

aspartate dehydrogenase domain containing

increases methylation
decreases expression
affects binding

EXP

furan results in increased methylation of ASPDH gene
furan results in decreased expression of ASPDH mRNA
furan binds to ASPDH protein

PMID:22079235 PMID:22240984 PMID:25539665

NCBI chr 1:104,094,983...104,097,244
Ensembl chr 1:104,094,954...104,097,244

G

asparaginase

decreases expression

EXP

furan results in decreased expression of ASPG mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417

G

assembly factor for spindle microtubules

increases expression

EXP

furan results in increased expression of ASPM mRNA

NCBI chr13:53,625,584...53,674,489
Ensembl chr13:53,625,584...53,674,489

G

asporin

increases expression

EXP

furan results in increased expression of ASPN mRNA

NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,287,065...15,310,632

G

argininosuccinate synthase 1

decreases expression
affects binding

EXP

furan results in decreased expression of ASS1 mRNA
furan binds to ASS1 protein

PMID:15120968 PMID:22240984

NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627

G

activating transcription factor 3

increases expression

ISO

furan results in increased expression of ATF3 mRNA

PMID:24183702 PMID:37517673

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

activating transcription factor 4

increases expression

ISO

furan results in increased expression of ATF4 mRNA

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

activating transcription factor 5

increases methylation

EXP

furan results in increased methylation of ATF5 gene

NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183

G

activating transcription factor 6

increases methylation

EXP

furan results in increased methylation of ATF6 gene

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

activating transcription factor 7 interacting protein

increases methylation

EXP

furan results in increased methylation of ATF7IP gene

NCBI chr 4:171,117,122...171,202,871
Ensembl chr 4:171,117,122...171,202,867

G

autophagy related 3

increases methylation

EXP

furan results in increased methylation of ATG3 gene

NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280

G

ATM serine/threonine kinase

increases expression
decreases expression

EXP

furan results in increased expression of ATM mRNA
furan results in decreased expression of ATM mRNA

PMID:22079235 PMID:25539665

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

antioxidant 1 copper chaperone

increases methylation

EXP

furan results in increased methylation of ATOX1 gene

NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585

G

ATPase Na+/K+ transporting subunit beta 1

increases methylation

EXP

furan results in increased methylation of ATP1B1 gene

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases methylation

EXP

furan results in increased methylation of ATP2A2 gene

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934

G

ATPase plasma membrane Ca2+ transporting 2

increases expression

ISO

furan results in increased expression of ATP2B2 mRNA

NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239

G

ATPase H+/K+ transporting subunit alpha

increases expression

EXP

furan results in increased expression of ATP4A mRNA

NCBI chr 1:95,089,122...95,102,277
Ensembl chr 1:95,089,122...95,102,277

G

ATP synthase F1 subunit beta

affects binding

EXP

furan binds to ATP5F1B protein

NCBI chr 7:1,100,058...1,106,461
Ensembl chr 7:1,099,860...1,106,462

G

ATP synthase inhibitory factor subunit 1

increases expression

EXP

furan results in increased expression of ATP5IF1 mRNA

NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677

G

ATP synthase membrane subunit G

increases methylation

EXP

furan results in increased methylation of ATP5MG gene

NCBI chr 8:54,122,457...54,130,407
Ensembl chr 8:54,122,457...54,132,831

G

ATPase H+ transporting V0 subunit D2

increases expression
decreases expression

ISO
EXP

furan results in increased expression of ATP6V0D2 mRNA
furan results in decreased expression of ATP6V0D2 mRNA

PMID:24183702 PMID:25539665 PMID:27387713

NCBI chr 5:38,133,151...38,182,245
Ensembl chr 5:38,133,158...38,182,245

G

ATPase, H+ transporting V0 subunit e2

increases expression

ISO
EXP

furan results in increased expression of ATP6V0E2 mRNA

PMID:24183702 PMID:26194646

NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680

G

ATPase H+ transporting V1 subunit D

increases expression

EXP

furan results in increased expression of ATP6V1D mRNA

NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346

G

ATPase phospholipid transporting 8B1

decreases methylation

EXP

furan results in decreased methylation of ATP8B1 gene

NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027

G

ataxin 7-like 3B

decreases expression

EXP

furan results in decreased expression of ATXN7L3B mRNA

NCBI chr 7:50,208,666...50,212,190
Ensembl chr 7:50,208,676...50,212,190

G

AU RNA binding methylglutaconyl-CoA hydratase

increases methylation

EXP

furan results in increased methylation of AUH gene

NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587

G

aurora kinase B

increases expression

EXP

furan results in increased expression of AURKB mRNA

NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285

G

advillin

increases expression

EXP

furan results in increased expression of AVIL mRNA

NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:64,711,403...64,729,436

G

arginine vasopressin

decreases expression

EXP

furan results in decreased expression of AVP mRNA

NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522

G

arginine vasopressin receptor 1A

decreases expression

EXP

furan results in decreased expression of AVPR1A mRNA

NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837

G

acyl-CoA wax alcohol acyltransferase 1

decreases expression

EXP

furan results in decreased expression of AWAT1 mRNA

NCBI chr X:69,708,286...69,714,531
Ensembl chr X:69,708,286...69,714,531

G

Axl receptor tyrosine kinase

increases expression

EXP

furan results in increased expression of AXL mRNA

NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009

G

alpha-2-glycoprotein 1, zinc-binding

decreases expression

EXP

furan results in decreased expression of AZGP1 mRNA

NCBI chr12:22,044,685...22,051,248
Ensembl chr12:22,044,751...22,053,020

G

5-azacytidine induced 2

increases methylation

EXP

furan results in increased methylation of AZI2 gene

NCBI chr 8:126,651,268...126,674,795
Ensembl chr 8:126,651,206...126,676,182

G

beta-2 microglobulin

decreases expression

EXP

furan results in decreased expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

increases expression

EXP

furan results in increased expression of B3GALNT1 mRNA

NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404

G

Beta-1,3-galactosyltransferase 5

increases expression

EXP

furan results in increased expression of B3GALT5 mRNA

NCBI chr11:49,053,959...49,100,398
Ensembl chr11:49,006,560...49,101,283

G

beta-1,4-N-acetyl-galactosaminyl transferase 4

decreases methylation
increases expression

EXP

furan results in decreased methylation of B4GALNT4 gene
furan results in increased expression of B4GALNT4 mRNA

NCBI chr 1:205,600,989...205,611,889
Ensembl chr 1:205,600,989...205,611,889

G

beta-1,4-galactosyltransferase 4

increases expression

EXP

furan results in increased expression of B4GALT4 mRNA

NCBI chr11:75,501,358...75,527,291
Ensembl chr11:75,501,366...75,527,177

G

beta-1,4-galactosyltransferase 5

increases expression

EXP

furan results in increased expression of B4GALT5 mRNA

NCBI chr 3:176,437,073...176,453,001
Ensembl chr 3:176,437,073...176,488,978

G

beta-1,4-galactosyltransferase 6

increases expression

EXP

furan results in increased expression of B4GALT6 mRNA

NCBI chr18:12,233,350...12,290,204
Ensembl chr18:12,233,351...12,290,204

G

BAALC binder of MAP3K1 and KLF4

increases expression

EXP

furan results in increased expression of BAALC mRNA

NCBI chr 7:71,803,640...71,877,608
Ensembl chr 7:71,774,898...71,879,261

G

bile acid CoA:amino acid N-acyltransferase

decreases expression

EXP

furan results in decreased expression of BAAT mRNA

NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181

G

beta-secretase 1

decreases expression

EXP

furan results in decreased expression of BACE1 mRNA

NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918

G

beta-secretase 2

increases methylation

EXP

furan results in increased methylation of BACE2 gene

NCBI chr11:50,176,852...50,258,948
Ensembl chr11:50,176,621...50,259,008

G

BAG cochaperone 6

increases methylation

EXP

furan results in increased methylation of BAG6 gene

NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,680,607...3,693,329

G

BAR/IMD domain containing adaptor protein 2 like 1

increases methylation
increases expression

EXP

furan results in increased methylation of BAIAP2L1 gene
furan results in increased expression of BAIAP2L1 mRNA

PMID:22079235 PMID:26194646

NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605

G

BCL2-antagonist/killer 1

increases expression

EXP

furan results in increased expression of BAK1 mRNA

PMID:22079235 PMID:26194646

NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974

G

Btg3 associated nuclear protein

increases methylation
increases expression

EXP

furan results in increased methylation of BANP gene
furan results in increased expression of BANP mRNA

PMID:22079235 PMID:26194646

NCBI chr19:66,916,417...66,994,286
Ensembl chr19:66,916,267...66,991,317

G

BRCA1 associated RING domain 1

increases expression

EXP

furan results in increased expression of BARD1 mRNA

NCBI chr 9:80,069,960...80,144,167
Ensembl chr 9:80,069,960...80,176,873

G

BARX homeobox 1

increases expression

EXP

furan results in increased expression of BARX1 mRNA

NCBI chr17:16,196,764...16,200,239
Ensembl chr17:16,196,764...16,200,239

G

basic leucine zipper ATF-like transcription factor 3

increases expression

EXP

furan results in increased expression of BATF3 mRNA

NCBI chr13:105,220,782...105,232,365
Ensembl chr13:105,220,390...105,232,369

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of BAX mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of BAX mRNA

PMID:20124500 PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

basal body orientation factor 1

increases expression

EXP

furan results in increased expression of BBOF1 mRNA

NCBI chr 6:109,786,363...109,812,153
Ensembl chr 6:109,786,363...109,812,147

G

Bardet-Biedl syndrome 10

decreases expression

ISO
EXP

furan results in decreased expression of BBS10 mRNA

PMID:24183702 PMID:25539665

NCBI chr 7:48,637,324...48,640,395
Ensembl chr 7:48,637,356...48,640,391

G

Bardet-Biedl syndrome 5

increases methylation

EXP

furan results in increased methylation of BBS5 gene

NCBI chr 3:74,818,104...74,839,658
Ensembl chr 3:74,818,473...74,857,023

G

brain enriched myelin associated protein 1

increases expression

EXP

furan results in increased expression of BCAS1 mRNA

NCBI chr 3:179,554,754...179,637,800
Ensembl chr 3:179,551,704...179,637,743

G

branched chain amino acid transaminase 1

increases expression

EXP

furan results in increased expression of BCAT1 mRNA

NCBI chr 4:179,695,662...179,777,973
Ensembl chr 4:179,695,662...179,777,288

G

butyrylcholinesterase

increases expression

EXP

furan results in increased expression of BCHE mRNA

NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760

G

branched chain keto acid dehydrogenase E1 subunit alpha

affects binding

EXP

furan binds to BCKDHA protein

NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:90,261,629...90,295,749

G

BCL10, immune signaling adaptor

increases expression

EXP

furan results in increased expression of BCL10 mRNA

PMID:20562052 PMID:22079235

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829

G

BCL2, apoptosis regulator

increases expression

EXP

furan results in increased expression of BCL2 mRNA

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

BCL2-related protein A1

increases expression

EXP

furan results in increased expression of BCL2A1 mRNA

NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890

G

Bcl2-like 1

increases methylation
increases expression

EXP

furan results in increased methylation of BCL2L1 gene
furan results in increased expression of BCL2L1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 11

increases expression

EXP

furan results in increased expression of BCL2L11 mRNA

PMID:20562052 PMID:22079235 PMID:25539665

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

Bcl2-like 14

increases expression

EXP

furan results in increased expression of BCL2L14 mRNA

NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079

G

Bcl2-like 15

increases expression

EXP

furan results in increased expression of BCL2L15 mRNA

NCBI chr 2:194,019,158...194,032,516
Ensembl chr 2:194,027,397...194,032,516

G

BCL3, transcription coactivator

decreases expression

EXP

furan results in decreased expression of BCL3 mRNA

NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368

G

BCL6, transcription repressor

increases methylation
increases expression

EXP

furan results in increased methylation of BCL6 gene
furan results in increased expression of BCL6 mRNA

PMID:22079235 PMID:26194646

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

BCL6B, transcription repressor

increases methylation
decreases expression

EXP

furan results in increased methylation of BCL6B gene
furan results in decreased expression of BCL6B mRNA

PMID:22079235 PMID:25539665

NCBI chr10:55,439,566...55,444,631
Ensembl chr10:55,432,382...55,444,631

G

beta-carotene oxygenase 1

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of BCO1 gene
furan results in increased expression of BCO1 mRNA

PMID:22079235 PMID:24183702

NCBI chr19:62,058,061...62,094,923
Ensembl chr19:62,058,089...62,094,917

G

bradykinin receptor B1

increases expression

EXP

furan results in increased expression of BDKRB1 mRNA

NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973

G

BEN domain containing 5

increases expression
decreases methylation

EXP

furan results in increased expression of BEND5 mRNA
furan results in decreased methylation of BEND5 gene

NCBI chr 5:131,519,214...131,565,228
Ensembl chr 5:131,519,214...131,762,906

G

BEN domain containing 7

decreases expression

EXP

furan results in decreased expression of BEND7 mRNA

NCBI chr17:78,392,489...78,475,459
Ensembl chr17:78,393,601...78,475,223

G

brain expressed X-linked 3

increases expression

EXP

furan results in increased expression of BEX3 mRNA

NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906

G

biglycan

increases expression

EXP

furan results in increased expression of BGN mRNA

NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799

G

basic helix-loop-helix family, member a15

increases methylation

EXP

furan results in increased methylation of BHLHA15 gene

NCBI chr12:15,534,123...15,538,299
Ensembl chr12:15,534,123...15,538,515

G

basic helix-loop-helix family, member e22

increases expression
decreases methylation

EXP

furan results in increased expression of BHLHE22 mRNA
furan results in decreased methylation of BHLHE22 gene

NCBI chr 2:102,402,622...102,405,732
Ensembl chr 2:102,400,164...102,420,508

G

basic helix-loop-helix family, member e40

decreases expression

EXP

furan results in decreased expression of BHLHE40 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783

G

betaine-homocysteine S-methyltransferase

affects binding
increases methylation

EXP

furan binds to BHMT protein
furan results in increased methylation of BHMT gene

PMID:22079235 PMID:22240984

NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715

G

betaine-homocysteine S-methyltransferase 2

increases methylation

EXP

furan results in increased methylation of BHMT2 gene

NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326

G

BICD family like cargo adaptor 1

increases expression

EXP

furan results in increased expression of BICDL1 mRNA

NCBI chr12:46,537,525...46,626,876
Ensembl chr12:46,538,396...46,628,866

G

BICD family like cargo adaptor 2

increases expression
decreases methylation

EXP

furan results in increased expression of BICDL2 mRNA
furan results in decreased methylation of BICDL2 gene

NCBI chr10:13,196,205...13,204,642
Ensembl chr10:13,195,913...13,204,642

G

BCL2-interacting killer

increases expression
decreases expression

EXP
ISO

furan results in increased expression of BIK mRNA
furan results in decreased expression of BIK mRNA

PMID:20562052 PMID:22079235 PMID:24183702 PMID:27387713

NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317

G

baculoviral IAP repeat-containing 3

increases expression

EXP

furan results in increased expression of BIRC3 mRNA

PMID:20562052 PMID:22079235

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590

G

baculoviral IAP repeat-containing 5

multiple interactions
increases expression

ISO
EXP

[Bromodeoxyuridine co-treated with furan] results in increased expression of BIRC5 mRNA
furan results in increased expression of BIRC5 mRNA

PMID:22079235 PMID:24183702 PMID:24910943 PMID:25539665

NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155

G

B-cell linker

increases expression

EXP

furan results in increased expression of BLNK mRNA

NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533

G

biogenesis of lysosomal organelles complex-1, subunit 1

increases methylation

EXP

furan results in increased methylation of BLOC1S1 gene

NCBI chr 7:1,931,985...1,935,614
Ensembl chr 7:1,925,335...1,936,049

G

biliverdin reductase B

decreases expression

EXP

furan results in decreased expression of BLVRB mRNA

NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225

G

basic helix-loop-helix ARNT like 1

increases expression

ISO

furan results in increased expression of BMAL1 mRNA

NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739

G

bMERB domain containing 1

decreases expression

EXP

furan results in decreased expression of BMERB1 mRNA

NCBI chr10:2,286,999...2,453,890
Ensembl chr10:2,287,000...2,453,728

G

Bcl2 modifying factor

increases methylation
decreases expression

EXP
ISO

furan results in increased methylation of BMF gene
furan results in decreased expression of BMF mRNA

PMID:22079235 PMID:24183702 PMID:25539665 PMID:26194646 PMID:37517673

NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258

G

bone morphogenetic protein 2

decreases expression

EXP

furan results in decreased expression of BMP2 mRNA

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760

G

bone morphogenetic protein 4

decreases methylation
increases expression

EXP

furan results in decreased methylation of BMP4 gene
furan results in increased expression of BMP4 mRNA

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172

G

BMP-binding endothelial regulator

increases expression

ISO
EXP

furan results in increased expression of BMPER mRNA

PMID:24183702 PMID:27387713

NCBI chr 8:30,008,049...30,253,201
Ensembl chr 8:30,008,148...30,434,359

G

BCL2 interacting protein like

decreases expression

EXP

furan results in decreased expression of BNIPL mRNA

NCBI chr 2:185,507,591...185,519,415
Ensembl chr 2:185,507,593...185,517,582

G

BCL2 family apoptosis regulator BOK

increases expression

EXP

furan results in increased expression of BOK mRNA

PMID:22079235 PMID:27387713

NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833

G

BPI fold containing family A, member 2

decreases methylation

EXP

furan results in decreased methylation of BPIFA2 gene

NCBI chr 3:162,953,538...162,961,497
Ensembl chr 3:162,953,538...162,961,496

G

BPI fold containing family A, member 3

decreases expression

EXP

furan results in decreased expression of BPIFA3 mRNA

NCBI chr 3:163,069,905...163,079,858
Ensembl chr 3:163,069,925...163,079,856

G

BPI fold containing family B, member 6

decreases expression

EXP

furan results in decreased expression of BPIFB6 mRNA

NCBI chr 3:162,841,640...162,855,471
Ensembl chr 3:162,841,644...162,855,470

G

BRCA1, DNA repair associated

increases expression
decreases expression

EXP

furan results in increased expression of BRCA1 mRNA
furan results in decreased expression of BRCA1 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

BRCA2, DNA repair associated

increases expression

EXP

furan results in increased expression of BRCA2 mRNA

PMID:20562052 PMID:22079235

NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194

G

bromodomain containing 2

increases expression

ISO

furan results in increased expression of BRD2 mRNA

NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290

G

bromodomain containing 3

increases methylation

EXP

furan results in increased methylation of BRD3 gene

NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629

G

BRCA1 interacting DNA helicase 1

increases expression

EXP

furan results in increased expression of BRIP1 mRNA

NCBI chr10:71,402,035...71,528,083
Ensembl chr10:71,401,151...71,575,206

G

basigin

increases methylation
increases expression

EXP

furan results in increased methylation of BSG gene
furan results in increased expression of BSG mRNA

PMID:22079235 PMID:26194646

NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:10,643,789...10,651,005

G

bassoon (presynaptic cytomatrix protein)

increases expression

EXP

furan results in increased expression of BSN mRNA

NCBI chr 8:117,663,447...117,754,412
Ensembl chr 8:117,670,334...117,754,412

G

B-box and SPRY domain containing

increases expression

EXP

furan results in increased expression of BSPRY mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:80,942,979...80,988,154

G

bone marrow stromal cell antigen 1

increases expression

EXP

furan results in increased expression of BST1 mRNA

NCBI chr14:71,466,179...71,482,671
Ensembl chr14:71,466,180...71,482,647

G

biotinidase

increases methylation

EXP

furan results in increased methylation of BTD gene

NCBI chr16:6,869,448...6,900,711
Ensembl chr16:6,869,291...6,901,410

G

basic transcription factor 3, pseudogene 8

increases expression

EXP

furan results in increased expression of BTF3-PS8 mRNA

NCBI chr 3:40,018,365...40,018,879

G

BTG anti-proliferation factor 1

decreases expression

EXP

furan results in decreased expression of BTG1 mRNA

NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406

G

BUB1 mitotic checkpoint serine/threonine kinase

increases expression

EXP

furan results in increased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921

G

BUD13 homolog

increases methylation

EXP

furan results in increased methylation of BUD13 gene

NCBI chr 8:55,471,818...55,487,652
Ensembl chr 8:55,471,810...55,487,649

G

basic leucine zipper and W2 domains 1

increases methylation

EXP

furan results in increased methylation of BZW1 gene

NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684

G

similar to human chromosome 16 open reading frame 90

increases expression

EXP

furan results in increased expression of C10H16ORF90 mRNA

NCBI chr10:12,125,235...12,138,441
Ensembl chr10:12,125,212...12,128,109

G

similar to human chromosome 17 open reading frame 58

increases methylation

EXP

furan results in increased methylation of C10H17ORF58 gene

NCBI chr10:92,472,779...92,477,330
Ensembl chr10:92,471,934...92,477,330

G

similar to human chromosome 5 open reading frame 15

increases methylation

EXP

furan results in increased methylation of C10H5ORF15 gene

NCBI chr10:37,064,889...37,077,493
Ensembl chr10:37,064,728...37,077,493

G

C1GALT1-specific chaperone 1

decreases expression

EXP

furan results in decreased expression of C1GALT1C1 mRNA

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

similar to human chromosome 11 open reading frame 24

increases expression

EXP

furan results in increased expression of C1H11ORF24 mRNA

NCBI chr 1:210,374,426...210,383,191
Ensembl chr 1:210,374,543...210,383,566

G

complement C1q binding protein

increases methylation
increases expression

EXP

furan results in increased methylation of C1QBP gene
furan results in increased expression of C1QBP mRNA

PMID:22079235 PMID:26194646

NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235

G

complement C1q like 3

increases methylation

EXP

furan results in increased methylation of C1QL3 gene

NCBI chr17:81,028,418...81,038,244
Ensembl chr17:81,028,418...81,038,244

G

C1q and TNF related 2

increases expression

EXP

furan results in increased expression of C1QTNF2 mRNA

NCBI chr10:28,443,326...28,460,400
Ensembl chr10:28,443,425...28,460,395

G

C1q and TNF related 3

decreases expression

EXP

furan results in decreased expression of C1QTNF3 mRNA

NCBI chr 2:61,644,225...61,666,640
Ensembl chr 2:61,644,276...61,666,559

G

C1q and TNF related 5

increases expression

EXP

furan results in increased expression of C1QTNF5 mRNA

NCBI chr 8:53,347,754...53,349,912
Ensembl chr 8:53,347,711...53,349,912

G

C1q and TNF related 7

increases expression

EXP

furan results in increased expression of C1QTNF7 mRNA

NCBI chr14:71,680,415...71,792,931
Ensembl chr14:71,680,479...71,792,865

G

complement C1r

decreases expression

EXP

furan results in decreased expression of C1R mRNA

NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714

G

complement C1r subcomponent like

decreases expression

EXP

furan results in decreased expression of C1RL mRNA

NCBI chr 4:159,080,495...159,097,066
Ensembl chr 4:159,080,495...159,097,066

G

complement C1s

decreases expression

EXP

furan results in decreased expression of C1S mRNA

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736

G

C2CD2-like

decreases expression

EXP

furan results in decreased expression of C2CD2L mRNA

NCBI chr 8:53,544,887...53,557,127
Ensembl chr 8:53,544,892...53,555,153

G

similar to human chromosome 1 open reading frame 52

increases methylation

EXP

furan results in increased methylation of C2H1ORF52 gene

NCBI chr 2:237,510,974...237,520,346
Ensembl chr 2:237,513,711...237,520,346

G

complement C3

decreases expression

EXP

furan results in decreased expression of C3 mRNA

PMID:15120968 PMID:26194646

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

similar to human chromosome 11 open reading frame 96

increases methylation

EXP

furan results in increased methylation of C3H11ORF96 gene

NCBI chr 3:100,375,474...100,376,717
Ensembl chr 3:100,351,199...100,378,346

G

complement C4A (Rodgers blood group)

decreases expression

EXP

furan results in decreased expression of C4A mRNA

NCBI chr20:4,010,306...4,024,707

G

complement C4B

decreases expression

EXP

furan results in decreased expression of C4B mRNA

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement component 4 binding protein, alpha

increases methylation
decreases expression

EXP

furan results in increased methylation of C4BPA gene
furan results in decreased expression of ZP3R mRNA

PMID:22079235 PMID:25539665

NCBI chr13:44,627,959...44,663,552
Ensembl chr13:44,627,982...44,663,471

G

complement component 4 binding protein, beta

decreases expression

EXP

furan results in decreased expression of C4BPB mRNA

NCBI chr13:44,673,064...44,683,781
Ensembl chr13:44,673,065...44,683,793

G

complement C5

decreases expression

EXP

furan results in decreased expression of C5 mRNA

PMID:25539665 PMID:26194646

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

complement C5a receptor 1

increases expression

EXP

furan results in increased expression of C5AR1 mRNA

NCBI chr 1:86,077,309...86,088,001

G

complement C5a receptor 2

decreases expression

EXP

furan results in decreased expression of C5AR2 mRNA

NCBI chr 1:86,058,557...86,073,583
Ensembl chr 1:86,057,256...86,061,372

G

similar to human chromosome 1 open reading frame 210

increases methylation

EXP

furan results in increased methylation of C5H1ORF210 gene

NCBI chr 5:137,334,142...137,337,300
Ensembl chr 5:137,334,142...137,337,300

G

similar to human chromosome 1 open reading frame 216

increases methylation

EXP

furan results in increased methylation of C5H1ORF216 gene

NCBI chr 5:144,168,240...144,189,761
Ensembl chr 5:144,184,603...144,190,546

G

complement C5 like 1

increases expression

EXP

furan results in increased expression of C5L1 mRNA

NCBI chr 3:38,799,165...38,818,443
Ensembl chr 3:38,799,731...38,817,527

G

complement C7

increases expression

EXP

furan results in increased expression of C7 mRNA

NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672

G

complement C8 beta chain

decreases expression

EXP

furan results in decreased expression of C8B mRNA

NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516

G

similar to human chromosome 3 open reading frame 18

decreases methylation

EXP

furan results in decreased methylation of C8H3ORF18 gene

NCBI chr 8:116,891,081...116,901,122
Ensembl chr 8:116,891,297...116,901,120

G

complement C9

decreases expression

EXP

furan results in decreased expression of C9 mRNA

NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752

G

carbonic anhydrase 11

decreases methylation
increases expression

EXP

furan results in decreased methylation of CAR11 gene
furan results in increased expression of CAR11 mRNA

NCBI chr 1:105,306,347...105,311,651
Ensembl chr 1:105,302,289...105,311,832

G

carbonic anhydrase 3

decreases expression

EXP

furan results in decreased expression of CAR3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524

G

carbonic anhydrase 4

increases expression

EXP

furan results in increased expression of CAR4 mRNA

NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916

G

carbonic anhydrase 5A

increases methylation

EXP

furan results in increased methylation of CAR5A gene

NCBI chr19:66,881,678...66,911,486
Ensembl chr19:66,881,693...66,911,486

G

carbonic anhydrase 5B

decreases expression
increases expression

EXP

furan results in decreased expression of CAR5B mRNA
furan results in increased expression of CAR5B mRNA

PMID:25539665 PMID:27387713

NCBI chr X:34,106,553...34,166,651
Ensembl chr X:34,067,403...34,166,653

G

calcium binding tyrosine phosphorylation regulated

increases expression

ISO

furan results in increased expression of CABYR mRNA

NCBI chr18:4,166,790...4,178,570
Ensembl chr18:4,166,858...4,179,507

G

calcium voltage-gated channel subunit alpha1 C

increases expression

EXP

furan results in increased expression of CACNA1C mRNA

NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762

G

calcium voltage-gated channel subunit alpha1 F

decreases methylation

EXP

furan results in decreased methylation of CACNA1F gene

NCBI chr X:17,539,992...17,568,308
Ensembl chr X:17,539,920...17,568,308

G

calcium voltage-gated channel subunit alpha1 S

decreases expression

EXP

furan results in decreased expression of CACNA1S mRNA

NCBI chr13:50,045,668...50,115,903
Ensembl chr13:50,045,668...50,115,903

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

increases expression
decreases methylation

EXP

furan results in increased expression of CACNA2D1 mRNA
furan results in decreased methylation of CACNA2D1 gene

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

calcium voltage-gated channel auxiliary subunit beta 3

increases expression

EXP

furan results in increased expression of CACNB3 mRNA

NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:131,662,545...131,676,085

G

calcium voltage-gated channel auxiliary subunit beta 4

increases methylation
decreases expression

EXP

furan results in increased methylation of CACNB4 gene
furan results in decreased expression of CACNB4 mRNA

PMID:22079235 PMID:25539665

NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:57,315,900...57,578,220

G

calcium voltage-gated channel auxiliary subunit gamma 2

decreases expression

EXP

furan results in decreased expression of CACNG2 mRNA

NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:111,455,006...111,577,757

G

calcium dependent secretion activator

increases expression

EXP

furan results in increased expression of CADPS mRNA

NCBI chr15:14,719,078...15,173,218
Ensembl chr15:14,720,726...15,173,211

G

cancer antigen 1

increases expression

EXP

furan results in increased expression of CAGE1 mRNA

NCBI chr17:26,995,671...27,033,740
Ensembl chr17:26,995,078...27,033,754

G

calcitonin-related polypeptide, beta

increases expression

EXP

furan results in increased expression of CALCB mRNA

NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654

G

calcium homeostasis modulator family member 5

increases expression

EXP

furan results in increased expression of CALHM5 mRNA

NCBI chr20:26,609,400...26,615,478
Ensembl chr20:26,609,400...26,615,478

G

calmodulin-like 4

increases expression

EXP

furan results in increased expression of CALML4 mRNA

NCBI chr 8:72,218,870...72,230,650
Ensembl chr 8:72,218,613...72,230,650

G

calneuron 1

decreases expression

EXP

furan results in decreased expression of CALN1 mRNA

NCBI chr12:31,447,964...31,939,847

G

calcium/calmodulin-dependent protein kinase II beta

increases expression

EXP

furan results in increased expression of CAMK2B mRNA

NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485

G

calcium/calmodulin-dependent protein kinase II delta

increases expression

EXP

furan results in increased expression of CAMK2D mRNA

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

increases expression

EXP

furan results in increased expression of CAMK2N1 mRNA

NCBI chr 5:155,958,116...155,959,897
Ensembl chr 5:155,957,878...155,961,058

G

calcium/calmodulin-dependent protein kinase IV

increases methylation

EXP

furan results in increased methylation of CAMK4 gene

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

calmodulin-lysine N-methyltransferase

increases methylation
increases expression

EXP

furan results in increased methylation of CAMKMT gene
furan results in increased expression of CAMKMT mRNA

PMID:22079235 PMID:25539665

NCBI chr 6:14,951,838...15,332,966
Ensembl chr 6:14,951,840...15,333,106

G

calmodulin regulated spectrin-associated protein family, member 2

decreases expression

EXP

furan results in decreased expression of CAMSAP2 mRNA

NCBI chr13:50,274,950...50,354,298
Ensembl chr13:50,274,950...50,354,298

G

calmodulin regulated spectrin-associated protein family, member 3

decreases expression

EXP

furan results in decreased expression of CAMSAP3 mRNA

NCBI chr12:6,440,959...6,464,582
Ensembl chr12:6,441,152...6,464,582

G

cyclase associated actin cytoskeleton regulatory protein 2

increases expression

EXP

furan results in increased expression of CAP2 mRNA

PMID:25539665 PMID:27387713

NCBI chr17:18,260,462...18,409,681
Ensembl chr17:18,261,646...18,409,563

G

capping actin protein, gelsolin like

increases expression

EXP

furan results in increased expression of CAPG mRNA

NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672

G

calpain 13

increases expression

EXP

furan results in increased expression of CAPN13 mRNA

NCBI chr 6:27,823,664...27,918,676
Ensembl chr 6:27,823,517...27,918,665

G

calpain 3

decreases expression

ISO

furan results in decreased expression of CAPN3 mRNA

NCBI chr 3:127,860,002...127,913,677
Ensembl chr 3:127,861,589...127,911,638

G

calpain 6

increases expression

EXP

furan results in increased expression of CAPN6 mRNA

NCBI chr X:112,177,467...112,202,178
Ensembl chr X:112,177,467...112,202,178

G

calpain 8

increases expression

EXP

furan results in increased expression of CAPN8 mRNA

NCBI chr13:96,783,640...96,847,825
Ensembl chr13:96,783,667...96,847,820

G

calpain, small subunit 2

increases expression

EXP

furan results in increased expression of CAPNS2 mRNA

NCBI chr19:30,277,324...30,278,266

G

calcyphosine 2

increases methylation

EXP

furan results in increased methylation of CAPS2 gene

NCBI chr 7:49,467,320...49,525,465
Ensembl chr 7:49,464,885...49,525,465

G

carbonic anhydrase 2

increases expression

ISO
EXP

furan results in increased expression of CAR2 mRNA
furan results in increased expression of CA2 mRNA; furan results in increased expression of CAR2 mRNA

PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064

G

caspase recruitment domain family, member 10

increases expression

EXP

furan results in increased expression of CARD10 mRNA

NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:112,210,776...112,239,806

G

caspase recruitment domain family, member 9

increases expression

EXP

furan results in increased expression of CARD9 mRNA

NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:29,569,959...29,578,402

G

capping protein regulator and myosin 1 linker 1

increases expression

EXP

furan results in increased expression of CARMIL1 mRNA

PMID:25539665 PMID:27387713

NCBI chr17:41,235,819...41,516,204
Ensembl chr17:41,236,229...41,516,221

G

capping protein regulator and myosin 1 linker 3

increases expression

EXP

furan results in increased expression of CARMIL3 mRNA

NCBI chr15:32,948,228...32,965,829
Ensembl chr15:32,948,856...32,965,811

G

caspase 1

increases expression
increases cleavage
multiple interactions

EXP
ISO

furan results in increased expression of CASP1 mRNA
furan results in increased cleavage of CASP1 protein
rhodioloside inhibits the reaction [furan results in increased cleavage of CASP1 protein]

PMID:22079235 PMID:34450210

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 12

increases expression
multiple interactions
increases cleavage

EXP
ISO

furan results in increased expression of CASP12 mRNA
rhodioloside inhibits the reaction [furan results in increased cleavage of CASP12 protein]

PMID:22079235 PMID:34450210

NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442

G

caspase 2

increases expression

EXP

furan results in increased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

multiple interactions
increases activity

EXP

protocatechuic acid inhibits the reaction [furan results in increased activity of CASP3 protein]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 6

increases methylation

EXP

furan results in increased methylation of CASP6 gene

NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726

G

caspase 8

increases expression

EXP

furan results in increased expression of CASP8 mRNA

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 8 associated protein 2

increases expression

EXP

furan results in increased expression of CASP8AP2 mRNA

NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632

G

caspase 9

increases expression
increases activity
multiple interactions

EXP

furan results in increased expression of CASP9 mRNA
furan results in increased activity of CASP9 protein
protocatechuic acid inhibits the reaction [furan results in increased activity of CASP9 protein]

PMID:20562052 PMID:32758512

Ensembl chr 5:159,391,188...159,409,648

G

calsequestrin 1

increases expression

EXP

furan results in increased expression of CASQ1 mRNA

PMID:25539665 PMID:27387713

NCBI chr13:87,203,021...87,212,710
Ensembl chr13:87,202,485...87,213,463

G

catalase

decreases expression
multiple interactions
decreases activity
increases methylation

EXP
ISO

furan results in decreased expression of CAT mRNA
rhodioloside inhibits the reaction [furan results in decreased activity of CAT protein]; rhodioloside inhibits the reaction [furan results in decreased expression of CAT mRNA]
protocatechuic acid inhibits the reaction [furan results in decreased activity of CAT protein]
furan results in increased methylation of CAT gene

PMID:15120968 PMID:22079235 PMID:32758512 PMID:34450210

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolin 1

increases expression

EXP

furan results in increased expression of CAV1 mRNA

NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740

G

caveolin 2

decreases expression

EXP

furan results in decreased expression of CAV2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425

G

caveolae associated protein 4

increases methylation

EXP

furan results in increased methylation of CAVIN4 gene

NCBI chr 5:67,792,171...67,893,094
Ensembl chr 5:67,792,392...67,803,254

G

Cbl proto-oncogene C

increases expression

EXP

furan results in increased expression of CBLC mRNA

PMID:25539665 PMID:27387713

NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709

G

cobalamin binding intrinsic factor

decreases expression

EXP

furan results in decreased expression of CBLIF mRNA

NCBI chr 1:218,030,756...218,045,004
Ensembl chr 1:218,030,731...218,045,117

G

cerebellin 2 precursor

increases methylation
decreases expression

EXP

furan results in increased methylation of CBLN2 gene
furan results in decreased expression of CBLN2 mRNA

PMID:22079235 PMID:25539665

NCBI chr18:82,215,210...82,222,648
Ensembl chr18:82,215,220...82,222,648

G

cerebellin 3 precursor

increases methylation
decreases expression

EXP

furan results in increased methylation of CBLN3 gene
furan results in decreased expression of CBLN3 mRNA

PMID:22079235 PMID:26194646

NCBI chr15:33,331,919...33,334,428
Ensembl chr15:33,331,919...33,334,428

G

carbonyl reductase 1

increases expression

ISO
EXP

furan results in increased expression of CBR1 mRNA

PMID:24183702 PMID:25539665

NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104

G

carbonyl reductase 3

increases expression

ISO

furan results in increased expression of CBR3 mRNA

PMID:24183702 PMID:37517673

NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558

G

chromobox 7

increases methylation

EXP

furan results in increased methylation of CBX7 gene

NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346

G

coiled-coil domain containing 102A

increases methylation

EXP

furan results in increased methylation of CCDC102A gene

NCBI chr19:10,108,553...10,124,652
Ensembl chr19:10,109,364...10,124,652

G

coiled-coil domain containing 120

increases expression

ISO

furan results in increased expression of CCDC120 mRNA

NCBI chr X:17,437,219...17,443,716
Ensembl chr X:17,425,624...17,444,717

G

coiled-coil domain containing 148

increases expression

EXP

furan results in increased expression of CCDC148 mRNA

NCBI chr 3:63,765,656...64,040,802
Ensembl chr 3:63,765,668...64,040,757

G

coiled-coil domain containing 163

decreases methylation

EXP

furan results in decreased methylation of CCDC163 gene

NCBI chr 5:135,408,981...135,415,574
Ensembl chr 5:135,409,003...135,415,577

G

coiled-coil domain containing 171

increases methylation

EXP

furan results in increased methylation of CCDC171 gene

NCBI chr 5:102,965,763...103,449,740
Ensembl chr 5:102,965,911...103,533,290

G

coiled-coil domain containing 22

decreases methylation

EXP

furan results in decreased methylation of CCDC22 gene

NCBI chr X:17,570,184...17,582,130
Ensembl chr X:17,535,659...17,582,130

G

coiled coil domain containing 28B

decreases expression

EXP

furan results in decreased expression of CCDC28B mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:147,246,627...147,251,629
Ensembl chr 5:147,246,628...147,251,629

G

coiled-coil domain containing 34

increases expression

EXP

furan results in increased expression of CCDC34 mRNA

NCBI chr 3:117,007,652...117,042,885
Ensembl chr 3:117,005,760...117,042,226

G

coiled-coil domain 39 molecular ruler complex subunit

increases expression

EXP

furan results in increased expression of CCDC39 mRNA

PMID:25539665 PMID:27387713

NCBI chr 2:118,593,881...118,631,584
Ensembl chr 2:118,593,881...118,631,647

G

coiled-coil domain containing 65

increases expression

EXP

furan results in increased expression of CCDC65 mRNA

NCBI chr 7:131,736,002...131,749,761
Ensembl chr 7:131,736,011...131,749,719

G

coiled-coil domain containing 68

increases methylation
increases expression

EXP

furan results in increased methylation of CCDC68 gene
furan results in increased expression of CCDC68 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526

G

coiled-coil domain containing 8

increases expression

EXP

furan results in increased expression of CCDC8 mRNA

NCBI chr 1:86,807,607...86,810,935
Ensembl chr 1:86,806,942...86,814,204

G

coiled-coil domain containing 80

increases expression

EXP

furan results in increased expression of CCDC80 mRNA

NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844

G

coiled-coil domain containing 81

decreases expression

EXP

furan results in decreased expression of CCDC81 mRNA

NCBI chr 1:153,152,032...153,203,586
Ensembl chr 1:153,152,034...153,203,984

G

coiled-coil domain containing 87

increases methylation

EXP

furan results in increased methylation of CCDC87 gene

NCBI chr 1:211,564,419...211,567,115
Ensembl chr 1:211,475,789...211,568,008

G

coiled-coil domain containing 92

increases expression

EXP

furan results in increased expression of CCDC92 mRNA

NCBI chr12:37,457,676...37,484,080
Ensembl chr12:37,457,068...37,484,327

G

C-C motif chemokine ligand 11

increases expression

EXP

furan results in increased expression of CCL11 mRNA

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575

G

C-C motif chemokine ligand 17

increases expression

EXP

furan results in increased expression of CCL17 mRNA

NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895

G

C-C motif chemokine ligand 19

decreases expression
increases expression

EXP

furan results in decreased expression of CCL19 mRNA
furan results in increased expression of CCL19 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022

G

C-C motif chemokine ligand 2

increases expression

EXP

furan results in increased expression of CCL2 mRNA

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 20

increases expression

EXP

furan results in increased expression of CCL20 mRNA

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736

G

C-C motif chemokine ligand 21

increases expression

EXP

furan results in increased expression of CCL21 mRNA

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 28

increases expression

EXP

furan results in increased expression of CCL28 mRNA

NCBI chr 2:53,334,071...53,358,709
Ensembl chr 2:53,334,071...53,358,709

G

C-C motif chemokine ligand 4

increases expression
decreases expression

ISO
EXP

furan results in increased expression of CCL4 mRNA
furan results in decreased expression of CCL4 mRNA

PMID:20194422 PMID:25539665

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine ligand 7

increases expression

EXP

furan results in increased expression of CCL7 mRNA

NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947

G

C-C motif chemokine ligand 9

increases methylation

EXP

furan results in increased methylation of CCL6 gene; furan results in increased methylation of CCL9 gene

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877

G

cellular communication network factor 1

decreases methylation

EXP

furan results in decreased methylation of CCN1 gene

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

cellular communication network factor 2

increases expression

EXP

furan results in increased expression of CCN2 mRNA; furan results in increased expression of CCN2 protein; furan results in increased expression of CTGF mRNA

PMID:27371368 PMID:27387713 PMID:38160780

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976

G

cellular communication network factor 5

increases methylation

EXP

furan results in increased methylation of CCN5 gene

NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062

G

cyclin A1

increases methylation

EXP

furan results in increased methylation of CCNA1 gene

NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300

G

cyclin A2

increases expression

EXP

furan results in increased expression of CCNA2 mRNA

PMID:20562052 PMID:22079235 PMID:25539665

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin B1

increases expression

EXP

furan results in increased expression of CCNB1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin B2

increases expression

EXP

furan results in increased expression of CCNB2 mRNA

NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682

G

cyclin D1

increases expression

EXP
ISO

furan results in increased expression of CCND1 mRNA

PMID:15120968 PMID:20124500 PMID:20194422 PMID:22079235 PMID:24183702 More...

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin D2

increases expression

EXP

furan results in increased expression of CCND2 mRNA

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301

G

cyclin E1

increases expression

EXP

furan results in increased expression of CCNE1 mRNA

PMID:20124500 PMID:22079235 PMID:25539665 PMID:27143483

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cyclin E2

increases expression

EXP

furan results in increased expression of CCNE2 mRNA

NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882

G

cyclin F

increases expression

EXP

furan results in increased expression of CCNF mRNA

NCBI chr10:13,757,884...13,783,669
Ensembl chr10:13,758,421...13,783,837

G

cyclin G1

increases expression

ISO
EXP

furan results in increased expression of CCNG1 mRNA

PMID:15120968 PMID:24183702 PMID:26194646 PMID:37517673

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

C-C motif chemokine receptor 1

increases expression

EXP

furan results in increased expression of CCR1 mRNA

NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374

G

C-C motif chemokine receptor 6

increases expression

EXP

furan results in increased expression of CCR6 mRNA

NCBI chr 1:55,022,037...55,055,857
Ensembl chr 1:55,021,833...55,046,059

G

chaperonin containing TCP1 subunit 4

increases methylation

EXP

furan results in increased methylation of CCT4 gene

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

chaperonin containing TCP1 subunit 5

increases expression

EXP

furan results in increased expression of CCT5 mRNA

NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779

G

CD164 molecule

increases methylation
decreases expression

EXP

furan results in increased methylation of CD164 gene
furan results in decreased expression of CD164 mRNA

PMID:22079235 PMID:26194646

NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649

G

CD177 molecule

increases expression

EXP

furan results in increased expression of CD177 mRNA

NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:89,467,926...89,488,443

G

CD180 molecule

increases expression

EXP

furan results in increased expression of CD180 mRNA

NCBI chr 2:35,589,889...35,602,837
Ensembl chr 2:35,589,451...35,603,982

G

Cd200 molecule

increases expression

EXP

furan results in increased expression of CD200 mRNA

NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569

G

CD24 molecule

increases expression
decreases methylation

EXP

furan results in increased expression of CD24 mRNA
furan results in decreased methylation of CD24 gene

PMID:26194646 PMID:27387713 PMID:38160780

NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785

G

CD244 molecule

increases expression

EXP

furan results in increased expression of CD244 mRNA

NCBI chr13:86,583,727...86,606,902
Ensembl chr13:86,584,826...86,616,009

G

Cd247 molecule

increases methylation

EXP

furan results in increased methylation of CD247 gene

NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248

G

CD248 molecule

increases expression

EXP

furan results in increased expression of CD248 mRNA

NCBI chr 1:211,803,052...211,805,616
Ensembl chr 1:211,801,934...211,805,776

G

CD274 molecule

decreases expression

EXP

furan results in decreased expression of CD274 mRNA

NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:236,496,463...236,549,951

G

Cd276 molecule

increases expression

EXP

furan results in increased expression of CD276 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 8:67,833,587...67,863,918
Ensembl chr 8:67,829,048...67,864,505

G

Cd300 molecule-like family member E

increases expression

EXP

furan results in increased expression of CD300LE mRNA

NCBI chr10:100,770,070...100,779,293
Ensembl chr10:100,770,030...100,779,293

G

Cd300 molecule-like family member F

increases methylation
decreases expression

EXP

furan results in increased methylation of CD300LF gene
furan results in decreased expression of CD300LF mRNA

PMID:22079235 PMID:25539665

NCBI chr10:100,858,924...100,875,111
Ensembl chr10:100,858,924...100,875,022

G

Cd300 molecule-like family member G

decreases expression

EXP

furan results in decreased expression of CD300LG mRNA

NCBI chr10:87,492,078...87,509,452
Ensembl chr10:87,492,106...87,508,585

G

CD3 delta subunit of T-cell receptor complex

increases expression

EXP

furan results in increased expression of CD3D mRNA

NCBI chr 8:54,184,573...54,190,112
Ensembl chr 8:54,175,155...54,196,722

G

CD3 epsilon subunit of T-cell receptor complex

increases expression

EXP

furan results in increased expression of CD3E mRNA

NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:54,200,617...54,211,876

G

CD3 gamma subunit of T-cell receptor complex

increases expression

EXP

furan results in increased expression of CD3G mRNA

NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:54,177,977...54,183,918

G

CD40 molecule

increases expression

EXP

furan results in increased expression of CD40 mRNA

PMID:22079235 PMID:27387713

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

CD40 ligand

increases expression

EXP

furan results in increased expression of CD40LG mRNA

NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475

G

CD44 molecule

increases expression

EXP

furan results in increased expression of CD44 mRNA

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

CD46 molecule

increases expression

EXP

furan results in increased expression of CD46 mRNA

NCBI chr13:109,104,122...109,134,903

G

Cd47 molecule

decreases methylation

EXP

furan results in decreased methylation of CD47 gene

NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272

G

CD55 molecule (Cromer blood group)

increases expression

EXP

furan results in increased expression of CD55 mRNA

NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107

G

Cd72 molecule

increases expression

EXP

furan results in increased expression of CD72 mRNA

NCBI chr 5:62,493,155...62,500,779
Ensembl chr 5:62,493,161...62,500,519

G

CD79b molecule

increases expression

EXP

furan results in increased expression of CD79B mRNA

NCBI chr10:91,739,134...91,742,312
Ensembl chr10:91,739,137...91,742,405

G

CD83 molecule

increases expression

EXP

furan results in increased expression of CD83 mRNA

NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047

G

CD86 molecule

increases expression

EXP

furan results in increased expression of CD86 mRNA

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361

G

cytidine deaminase

increases expression

EXP

furan results in increased expression of CDA mRNA

NCBI chr 5:155,839,929...155,866,541
Ensembl chr 5:155,839,929...155,866,541

G

cell division cycle 20

increases expression

EXP

furan results in increased expression of CDC20 mRNA

NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799

G

cell division cycle 25A

increases expression

EXP

furan results in increased expression of CDC25A mRNA

NCBI chr 8:118,742,824...118,761,190
Ensembl chr 8:118,742,426...118,761,188

G

cell division cycle 25C

increases expression

EXP

furan results in increased expression of CDC25C mRNA

NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292

G

CDC42 binding protein kinase gamma

increases methylation

EXP

furan results in increased methylation of CDC42BPG gene

NCBI chr 1:213,037,603...213,057,764
Ensembl chr 1:213,037,836...213,057,765

G

CDC42 effector protein 1

increases methylation

EXP

furan results in increased methylation of CDC42EP1 gene

NCBI chr 7:112,275,759...112,283,665
Ensembl chr 7:112,275,792...112,283,664

G

CDC42 effector protein 2

increases expression
decreases methylation

EXP

furan results in increased expression of CDC42EP2 mRNA
furan results in decreased methylation of CDC42EP2 gene

NCBI chr 1:212,631,317...212,640,231
Ensembl chr 1:212,629,881...212,640,234

G

CDC42 effector protein 4

increases expression

EXP

furan results in increased expression of CDC42EP4 mRNA

NCBI chr10:99,271,750...99,298,551
Ensembl chr10:99,267,540...99,300,168

G

CDC42 effector protein 5

increases methylation
increases expression

EXP

furan results in increased methylation of CDC42EP5 gene
furan results in increased expression of CDC42EP5 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:79,108,036...79,110,550

G

CDC42 small effector 1

decreases methylation

EXP

furan results in decreased methylation of CDC42SE1 gene

NCBI chr 2:185,494,692...185,502,519
Ensembl chr 2:185,496,547...185,502,514

G

cell division cycle 45

increases expression

EXP

furan results in increased expression of CDC45 mRNA

NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981

G

cell division cycle 6

increases expression

EXP

furan results in increased expression of CDC6 mRNA

NCBI chr10:84,360,361...84,374,239
Ensembl chr10:84,360,381...84,374,241

G

cell division cycle associated 2

increases expression

EXP

furan results in increased expression of CDCA2 mRNA

NCBI chr15:46,071,360...46,117,524
Ensembl chr15:46,071,360...46,116,639

G

cell division cycle associated 3

increases expression

EXP

furan results in increased expression of CDCA3 mRNA

NCBI chr 4:159,321,203...159,325,072
Ensembl chr 4:159,321,014...159,325,068

G

cell division cycle associated 7

increases expression

EXP

furan results in increased expression of CDCA7 mRNA

NCBI chr 3:77,730,315...77,740,950
Ensembl chr 3:77,729,970...77,740,947

G

CUB domain containing protein 1

increases expression

EXP

furan results in increased expression of CDCP1 mRNA

NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:131,706,140...131,742,877

G

CUB domain containing protein 2

decreases expression

EXP

furan results in decreased expression of CDCP2 mRNA

NCBI chr 5:127,106,380...127,124,243
Ensembl chr 5:127,106,345...127,123,027

G

cadherin 1

increases methylation

EXP

furan results in increased methylation of CDH1 gene

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

cadherin 11

increases expression

EXP

furan results in increased expression of CDH11 mRNA

NCBI chr19:2,152,961...2,312,140
Ensembl chr19:2,154,840...2,312,140

G

cadherin 13

increases expression

EXP

furan results in increased expression of CDH13 mRNA

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119

G

cadherin 3

increases expression

EXP

furan results in increased expression of CDH3 mRNA

NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257

G

cadherin 5

increases methylation

EXP

furan results in increased methylation of CDH5 gene

NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822

G

cadherin 6

increases expression

EXP

furan results in increased expression of CDH6 mRNA

NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287

G

cadherin-related family member 5

increases expression

EXP

furan results in increased expression of CDHR5 mRNA

NCBI chr 1:205,802,686...205,811,184
Ensembl chr 1:205,802,686...205,811,093

G

cyclin-dependent kinase 1

increases expression

EXP

furan results in increased expression of CDK1 mRNA

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin dependent kinase 2

increases expression

EXP

furan results in increased expression of CDK2 mRNA

NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878

G

cyclin-dependent kinase 4

increases methylation

EXP

furan results in increased methylation of CDK4 gene

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163

G

cyclin dependent kinase like 1

increases methylation
increases expression

EXP

furan results in increased methylation of CDKL1 gene
furan results in increased expression of CDKL1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 6:93,960,157...94,005,207
Ensembl chr 6:93,959,911...94,006,115

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

ISO
EXP

[Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA
furan results in increased expression of CDKN1A mRNA

PMID:20124500 PMID:20194422 PMID:23853263 PMID:24183702 PMID:24910943 More...

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1B

increases expression

EXP

furan results in increased expression of CDKN1B mRNA

NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498

G

cyclin-dependent kinase inhibitor 2A

increases expression

EXP

furan results in increased expression of CDKN2A mRNA

PMID:20562052 PMID:22079235

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

cyclin-dependent kinase inhibitor 2B

increases expression

EXP

furan results in increased expression of CDKN2B mRNA

PMID:20562052 PMID:22079235 PMID:27387713

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855

G

cyclin-dependent kinase inhibitor 3

increases methylation

EXP

furan results in increased methylation of CDKN3 gene

NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722

G

cysteine dioxygenase type 1

decreases expression

EXP

furan results in decreased expression of CDO1 mRNA

NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891

G

cerebellar degeneration-related protein 2

increases expression

EXP

furan results in increased expression of CDR2 mRNA

NCBI chr 1:184,934,128...184,959,036
Ensembl chr 1:184,934,129...184,968,863

G

CDP-diacylglycerol synthase 1

increases expression

EXP

furan results in increased expression of CDS1 mRNA

NCBI chr14:8,126,678...8,187,243
Ensembl chr14:8,124,838...8,187,218

G

caudal type homeo box 2

increases expression

EXP

furan results in increased expression of CDX2 mRNA

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

chromodomain Y-like

increases expression

EXP

furan results in increased expression of CDYL mRNA

NCBI chr17:29,188,697...29,409,805
Ensembl chr17:29,188,698...29,409,757

G

CEA cell adhesion molecule 9

increases methylation

EXP

furan results in increased methylation of CEACAM3 gene

NCBI chr 1:86,533,724...86,538,259
Ensembl chr 1:86,533,724...86,538,260

G

CCAAT/enhancer binding protein delta

increases expression

EXP

furan results in increased expression of CEBPD mRNA

NCBI chr11:98,268,856...98,269,994
Ensembl chr11:98,265,651...98,280,824

G

CUGBP, Elav-like family member 2

decreases expression

EXP

furan results in decreased expression of CELF2 mRNA

NCBI chr17:75,813,928...76,639,300
Ensembl chr17:75,813,704...76,636,362

G

CUGBP, Elav-like family member 3

increases methylation

EXP

furan results in increased methylation of CELF3 gene

NCBI chr 2:184,805,078...184,819,189
Ensembl chr 2:184,805,081...184,819,187

G

cadherin, EGF LAG seven-pass G-type receptor 3

increases methylation

EXP

furan results in increased methylation of CELSR3 gene

NCBI chr 8:118,409,136...118,438,593
Ensembl chr 8:118,409,136...118,436,847

G

centromere protein A

increases methylation
increases expression

EXP

furan results in increased methylation of CENPA gene
furan results in increased expression of CENPA mRNA

PMID:22079235 PMID:25539665

NCBI chr 6:31,420,062...31,431,703

G

centromere protein C

increases methylation

EXP

furan results in increased methylation of CENPC1 gene

NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590

G

centromere protein F

increases expression

EXP

furan results in increased expression of CENPF mRNA

NCBI chr13:103,715,344...103,760,931
Ensembl chr13:103,715,344...103,760,886

G

centromere protein Q

increases expression

EXP

furan results in increased expression of CENPQ mRNA

NCBI chr 9:27,454,339...27,469,371
Ensembl chr 9:27,454,252...27,469,366

G

centromere protein T

increases expression

EXP

furan results in increased expression of CENPT mRNA

NCBI chr19:50,644,548...50,651,048
Ensembl chr19:50,634,368...50,651,037

G

centrosomal protein 152

increases expression

EXP

furan results in increased expression of CEP152 mRNA

NCBI chr 3:133,243,979...133,332,271
Ensembl chr 3:133,263,174...133,331,655
Ensembl chr 3:133,263,174...133,331,655

G

centrosomal protein 41

increases expression

EXP

furan results in increased expression of CEP41 mRNA

NCBI chr 4:60,238,602...60,279,670
Ensembl chr 4:60,239,539...60,254,419

G

centrosomal protein 55

increases expression

EXP

furan results in increased expression of CEP55 mRNA

NCBI chr 1:245,245,272...245,260,835
Ensembl chr 1:245,245,306...245,260,890

G

centrosomal protein 57-like 1

increases expression

EXP

furan results in increased expression of CEP57L1 mRNA

NCBI chr20:46,820,350...46,876,911
Ensembl chr20:46,820,353...46,876,926

G

centrosomal protein 70

increases expression

EXP

furan results in increased expression of CEP70 mRNA

NCBI chr 8:108,689,562...108,742,620
Ensembl chr 8:108,689,671...108,742,617

G

centrosomal protein 72

increases expression

EXP

furan results in increased expression of CEP72 mRNA

NCBI chr 1:31,053,884...31,083,863
Ensembl chr 1:31,053,914...31,083,863

G

cerebral endothelial cell adhesion molecule

increases expression

EXP

furan results in increased expression of CERCAM mRNA

NCBI chr 3:33,515,513...33,553,817
Ensembl chr 3:33,486,664...33,553,813

G

ceramide synthase 1

increases methylation

EXP

furan results in increased methylation of CERS1 gene

NCBI chr16:19,131,271...19,146,480
Ensembl chr16:19,131,276...19,146,480

G

carboxylesterase 1D

decreases expression

EXP

furan results in decreased expression of CES1D mRNA

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

carboxylesterase 2A

decreases methylation

EXP

furan results in decreased methylation of CES2A gene

NCBI chr19:135,885...142,935
Ensembl chr19:135,885...142,935

G

carboxylesterase 2C

multiple interactions
increases expression

ISO
EXP

[Bromodeoxyuridine co-treated with furan] affects the expression of CES2C mRNA
furan results in increased expression of CES2C mRNA

PMID:24910943 PMID:25539665 PMID:26194646 PMID:37517673

NCBI chr 1:270,377,201...270,384,768
Ensembl chr 1:270,374,913...270,384,801

G

carboxylesterase 2E

increases expression

ISO

furan results in increased expression of CES2E mRNA

NCBI chr19:163,899...179,274
Ensembl chr19:163,859...179,308

G

carboxylesterase 2H

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of CES2H gene
furan results in increased expression of CES2 mRNA

PMID:22079235 PMID:24183702

NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752

G

carboxylesterase 3a

decreases expression

EXP

furan results in decreased expression of CES3 mRNA

NCBI chr19:49,902,312...49,910,484

G

carboxylesterase 5A

decreases expression

EXP

furan results in decreased expression of CES5A mRNA

NCBI chr19:11,198,829...11,504,887
Ensembl chr19:11,419,189...11,504,887

G

cilia and flagella associated protein 20

increases expression

EXP

furan results in increased expression of CFAP20 mRNA

NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612

G

cilia and flagella associated protein 210

increases expression

EXP

furan results in increased expression of CFAP210 mRNA

NCBI chr 3:74,928,368...74,962,508
Ensembl chr 3:74,927,880...74,962,497

G

cilia and flagella associated protein 263

increases expression

EXP

furan results in increased expression of CCDC113 mRNA

NCBI chr19:9,503,062...9,522,957
Ensembl chr19:9,503,066...9,522,957

G

cilia and flagella associated protein 45

increases methylation

EXP

furan results in increased methylation of CFAP45 gene

NCBI chr13:87,521,831...87,545,236
Ensembl chr13:87,521,518...87,545,234

G

complement factor B

decreases expression

EXP

furan results in decreased expression of CFB mRNA

NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740

G

complement factor H

decreases expression

EXP

furan results in decreased expression of CFH mRNA

PMID:25539665 PMID:26194646

NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532

G

complement factor H-related 1

decreases expression

EXP

furan results in decreased expression of CFHR1 mRNA

NCBI chr13:53,946,298...53,961,282
Ensembl chr13:53,919,927...53,961,303

G

complement factor I

decreases expression

EXP

furan results in decreased expression of CFI mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:221,062,206...221,104,790
Ensembl chr 2:221,062,212...221,104,786

G

CF transmembrane conductance regulator

increases expression

EXP

furan results in increased expression of CFTR mRNA

PMID:26194646 PMID:27387713 PMID:38160780

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643

G

cell growth regulator with EF hand domain 1

increases expression

ISO
EXP

furan results in increased expression of CGREF1 mRNA

PMID:24183702 PMID:25539665 PMID:26194646 PMID:37517673

NCBI chr 6:31,151,795...31,163,801
Ensembl chr 6:31,151,795...31,163,800

G

cholesterol 25-hydroxylase

increases methylation
increases expression

EXP

furan results in increased methylation of CH25H gene
furan results in increased expression of CH25H mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:241,428,048...241,429,366
Ensembl chr 1:241,331,619...241,431,190

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

ISO

furan results in decreased expression of CHAC1 mRNA

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361

G

chromatin assembly factor 1 subunit A

increases expression

ISO
EXP

furan results in increased expression of CHAF1A mRNA

PMID:20194422 PMID:22079235 PMID:25539665

NCBI chr 9:961,225...987,825
Ensembl chr 9:961,084...987,868

G

chromatin assembly factor 1 subunit B

increases expression

EXP

furan results in increased expression of CHAF1B mRNA

NCBI chr11:46,670,560...46,690,739
Ensembl chr11:46,670,630...46,690,733

G

coiled-coil-helix-coiled-coil-helix domain containing 2

increases methylation

EXP

furan results in increased methylation of CHCHD2 gene

NCBI chr12:32,464,847...32,470,871
Ensembl chr12:32,464,824...32,470,871

G

chromodomain helicase DNA binding protein 7

increases methylation

EXP

furan results in increased methylation of CHD7 gene

NCBI chr 5:26,609,245...26,792,736
Ensembl chr 5:26,609,407...26,792,734

G

checkpoint kinase 1

increases expression

ISO
EXP

furan results in increased expression of CHEK1 mRNA

PMID:20194422 PMID:20562052 PMID:22079235 PMID:25539665

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359

G

checkpoint kinase 2

increases expression

ISO
EXP

furan results in increased expression of CHEK2 mRNA

PMID:20194422 PMID:25539665

NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667

G

chromogranin A

increases methylation
increases expression

EXP

furan results in increased methylation of CHGA gene
furan results in increased expression of CHGA mRNA

PMID:22079235 PMID:27387713

NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237

G

chromogranin B

increases expression

EXP

furan results in increased expression of CHGB mRNA

NCBI chr 3:140,496,712...140,510,057
Ensembl chr 3:140,495,951...140,510,054

G

chitinase 3 like 1

increases expression

EXP

furan results in increased expression of CHI3L1 mRNA

NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825

G

chitinase 1

increases methylation

EXP

furan results in increased methylation of CHIT1 gene

NCBI chr13:48,117,886...48,165,645
Ensembl chr13:48,145,893...48,165,639

G

choline kinase alpha

increases expression

ISO

furan results in increased expression of CHKA mRNA

NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752

G

CHM Rab escort protein

decreases expression

EXP

furan results in decreased expression of CHM mRNA

NCBI chr X:82,395,463...82,554,249
Ensembl chr X:82,396,816...82,568,642

G

charged multivesicular body protein 5

increases methylation

EXP

furan results in increased methylation of CHMP5 gene

NCBI chr 5:60,877,369...60,894,512
Ensembl chr 5:60,877,341...60,894,511

G

chimerin 1

increases expression

EXP

furan results in increased expression of CHN1 mRNA

NCBI chr 3:78,917,329...79,084,040
Ensembl chr 3:78,917,329...79,084,197

G

calcineurin-like EF hand protein 2

increases expression

EXP

furan results in increased expression of CHP2 mRNA

NCBI chr 1:186,189,090...186,203,663
Ensembl chr 1:186,185,151...186,203,667

G

chordin-like 2

increases expression

EXP

furan results in increased expression of CHRDL2 mRNA

NCBI chr 1:163,755,316...163,782,758
Ensembl chr 1:163,755,316...163,782,757

G

cholinergic receptor, muscarinic 2

decreases expression

EXP

furan results in decreased expression of CHRM2 mRNA

NCBI chr 4:65,981,136...66,116,128
Ensembl chr 4:65,981,006...66,126,464

G

cholinergic receptor, muscarinic 3

increases expression

EXP

furan results in increased expression of CHRM3 mRNA

NCBI chr17:64,696,549...65,158,622
Ensembl chr17:64,696,066...65,173,304

G

cholinergic receptor nicotinic alpha 10 subunit

increases expression

EXP

furan results in increased expression of CHRNA10 mRNA

NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:165,899,261...165,903,458

G

cholinergic receptor nicotinic alpha 5 subunit

increases methylation

EXP

furan results in increased methylation of CHRNA5 gene

NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:64,265,879...64,294,233

G

cholinergic receptor nicotinic alpha 6 subunit

increases methylation

EXP

furan results in increased methylation of CHRNA6 gene

NCBI chr16:71,400,615...71,407,315
Ensembl chr16:71,400,615...71,407,315

G

cholinergic receptor nicotinic beta 1 subunit

increases expression

EXP

furan results in increased expression of CHRNB1 mRNA

NCBI chr10:54,999,943...55,015,137
Ensembl chr10:55,002,788...55,015,107

G

cholinergic receptor nicotinic beta 2 subunit

decreases expression

EXP

furan results in decreased expression of CHRNB2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326

G

carbohydrate sulfotransferase 1

increases expression

EXP

furan results in increased expression of CHST1 mRNA

NCBI chr 3:99,003,987...99,030,214
Ensembl chr 3:99,009,958...99,031,262

G

carbohydrate sulfotransferase 10

increases expression
decreases methylation

EXP

furan results in increased expression of CHST10 mRNA
furan results in decreased methylation of CHST10 gene

NCBI chr 9:48,588,575...48,618,487
Ensembl chr 9:48,588,575...48,618,442

G

carbohydrate sulfotransferase 12

increases methylation

EXP

furan results in increased methylation of CHST12 gene

NCBI chr12:19,224,545...19,243,012
Ensembl chr12:19,220,141...19,243,047

G

carbohydrate sulfotransferase 14

increases expression

EXP

furan results in increased expression of CHST14 mRNA

NCBI chr 3:126,370,348...126,372,405
Ensembl chr 3:126,370,348...126,372,777

G

carbohydrate sulfotransferase 7

increases expression

EXP

furan results in increased expression of CHST7 mRNA

NCBI chr X:4,949,810...4,986,372
Ensembl chr X:4,938,757...4,986,907

G

carbohydrate sulfotransferase 8

increases methylation

EXP

furan results in increased methylation of CHST8 gene

NCBI chr 1:96,431,144...96,572,880
Ensembl chr 1:96,431,145...96,572,880

G

carbohydrate sulfotransferase 9

increases expression

EXP

furan results in increased expression of CHST9 mRNA

NCBI chr18:6,850,874...7,125,222
Ensembl chr18:6,851,831...7,125,161

G

chromosome transmission fidelity factor 18

increases expression

EXP

furan results in increased expression of CHTF18 mRNA

NCBI chr10:15,247,525...15,255,573
Ensembl chr10:15,246,362...15,255,685

G

cytosolic iron-sulfur assembly component 3

increases methylation

EXP

furan results in increased methylation of CIAO3 gene

NCBI chr10:15,300,403...15,309,467
Ensembl chr10:15,300,471...15,309,468

G

circadian associated repressor of transcription

increases methylation

EXP

furan results in increased methylation of CIART gene

NCBI chr 2:186,108,744...186,113,778
Ensembl chr 2:186,108,752...186,112,246

G

calcium and integrin binding family member 2

increases expression

EXP

furan results in increased expression of CIB2 mRNA

NCBI chr 8:63,826,410...63,843,301
Ensembl chr 8:63,826,411...63,843,277

G

calcium and integrin binding family member 3

increases expression

EXP

furan results in increased expression of CIB3 mRNA

NCBI chr16:17,656,453...17,665,848
Ensembl chr16:17,656,453...17,665,848

G

cell death-inducing DFFA-like effector b

decreases expression

EXP

furan results in decreased expression of CIDEB mRNA

NCBI chr15:33,222,135...33,226,407
Ensembl chr15:33,221,824...33,226,688

G

cell death-inducing DFFA-like effector c

increases expression

ISO

furan results in increased expression of CIDEC mRNA

PMID:24183702 PMID:37517673

NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806

G

cartilage intermediate layer protein

increases expression

EXP

furan results in increased expression of CILP mRNA

NCBI chr 8:74,671,696...74,687,420
Ensembl chr 8:74,671,534...74,687,409

G

cartilage intermediate layer protein 2

increases methylation

EXP

furan results in increased methylation of CILP2 gene

NCBI chr16:19,573,821...19,581,100
Ensembl chr16:19,573,908...19,581,100

G

ciliary microtubule associated protein 1B

increases expression

EXP

furan results in increased expression of CIMAP1B mRNA

NCBI chr 7:122,323,860...122,326,921
Ensembl chr 7:122,323,860...122,326,876

G

cyclin-dependent kinase 2-interacting protein

increases expression

EXP

furan results in increased expression of CINP mRNA

NCBI chr 6:135,698,477...135,720,798
Ensembl chr 6:135,706,793...135,720,689

G

CLOCK-interacting pacemaker

increases methylation

EXP

furan results in increased methylation of CIPC gene

NCBI chr 6:112,325,980...112,344,692
Ensembl chr 6:112,325,671...112,344,692

G

cytokine inducible SH2-containing protein

decreases expression

EXP

furan results in decreased expression of CISH mRNA

NCBI chr 8:116,850,969...116,855,917
Ensembl chr 8:116,850,773...116,855,986

G

citron rho-interacting serine/threonine kinase

increases methylation

EXP

furan results in increased methylation of CIT gene

NCBI chr12:46,263,881...46,425,642
Ensembl chr12:46,266,369...46,424,656

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

EXP

furan results in decreased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782

G

cytoskeleton associated protein 2

increases expression

EXP

furan results in increased expression of CKAP2 mRNA

NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352

G

cytoskeleton-associated protein 4

increases expression
decreases methylation

EXP

furan results in increased expression of CKAP4 mRNA
furan results in decreased methylation of CKAP4 gene

PMID:25539665 PMID:27387713

NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624

G

creatine kinase B

increases expression

EXP

furan results in increased expression of CKB mRNA

NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478

G

creatine kinase, M-type

decreases expression

EXP

furan results in decreased expression of CKM mRNA

NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719

G

creatine kinase, mitochondrial 1

increases expression

EXP

furan results in increased expression of CKMT1B mRNA

NCBI chr 3:128,783,408...128,789,485
Ensembl chr 3:128,783,597...128,789,483

G

chloride channel accessory 1

increases methylation
increases expression

EXP

furan results in increased methylation of CLCA1 gene
furan results in increased expression of CLCA1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714

G

chloride channel accessory 2

increases expression

EXP

furan results in increased expression of CLCA2 mRNA

NCBI chr 2:236,655,419...236,682,669
Ensembl chr 2:236,639,545...236,685,129

G

chloride channel accessory 4

increases expression

EXP

furan results in increased expression of CLCA4 mRNA

NCBI chr 2:236,543,975...236,565,096
Ensembl chr 2:236,544,201...236,563,435

G

chloride channel calcium activated 4-like

increases expression

EXP

furan results in increased expression of CLCA4L mRNA

NCBI chr 2:236,486,485...236,506,483
Ensembl chr 2:236,486,485...236,506,483

G

cardiotrophin-like cytokine factor 1

increases expression

EXP

furan results in increased expression of CLCF1 mRNA

NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064

G

chloride voltage-gated channel 4

decreases expression

EXP

furan results in decreased expression of CLCN4 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:27,290,769...27,356,967
Ensembl chr X:27,290,868...27,356,939

G

chloride voltage-gated channel 6

decreases expression

EXP

furan results in decreased expression of CLCN6 mRNA

NCBI chr 5:163,715,593...163,748,301
Ensembl chr 5:163,717,439...163,748,198

G

chloride voltage-gated channel Kb

increases expression

EXP

furan results in increased expression of CLCNKB mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:158,993,073...159,005,618
Ensembl chr 5:158,993,074...159,004,900

G

claudin 11

increases methylation

EXP

furan results in increased methylation of CLDN11 gene

NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539

G

claudin 14

increases methylation

EXP

furan results in increased methylation of CLDN14 gene

NCBI chr11:46,701,940...46,799,049
Ensembl chr11:46,701,940...46,799,096

G

claudin 19

decreases expression

EXP

furan results in decreased expression of CLDN19 mRNA

NCBI chr 5:138,148,234...138,155,672
Ensembl chr 5:138,148,501...138,155,666

G

claudin 2

decreases expression

EXP

furan results in decreased expression of CLDN2 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:108,248,383...108,258,847
Ensembl chr X:108,237,676...108,262,377

G

claudin 22

decreases expression

EXP

furan results in decreased expression of CLDN22 mRNA

NCBI chr16:51,155,058...51,156,084

G

claudin 23

increases expression

EXP

furan results in increased expression of CLDN23 mRNA

PMID:25539665 PMID:27387713

NCBI chr16:63,117,045...63,118,769
Ensembl chr16:63,116,781...63,118,957

G

claudin 3

increases methylation

EXP

furan results in increased methylation of CLDN3 gene

NCBI chr12:27,345,075...27,346,547
Ensembl chr12:27,345,076...27,348,841

G

claudin 4

increases expression

EXP

furan results in increased expression of CLDN4 mRNA

PMID:26194646 PMID:27387713 PMID:38160780

NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958

G

claudin 5

increases expression

EXP

furan results in increased expression of CLDN5 mRNA

NCBI chr11:95,717,172...95,718,598
Ensembl chr11:95,717,176...95,719,322

G

claudin 6

increases methylation

EXP

furan results in increased methylation of CLDN6 gene

NCBI chr10:13,213,837...13,218,578
Ensembl chr10:13,213,956...13,218,581

G

claudin 7

increases expression

EXP

furan results in increased expression of CLDN7 mRNA

NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905

G

C-type lectin domain containing 10A

increases expression

EXP

furan results in increased expression of CLEC10A mRNA

PMID:26194646 PMID:27387713

NCBI chr10:55,374,914...55,379,110
Ensembl chr10:55,374,887...55,379,108

G

C-type lectin domain containing 11A

increases methylation
increases expression

EXP

furan results in increased methylation of CLEC11A gene
furan results in increased expression of CLEC11A mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784

G

C-type lectin domain family 12, member A

increases expression

EXP

furan results in increased expression of CLEC12A mRNA

NCBI chr 4:164,484,162...164,502,793
Ensembl chr 4:164,484,162...164,510,233

G

C-type lectin domain family 2, member D

increases expression

EXP

furan results in increased expression of CLEC2D mRNA

NCBI chr 4:163,902,124...163,925,587
Ensembl chr 4:163,902,547...163,925,587

G

C-type lectin domain family 4, member A1

increases expression

EXP

furan results in increased expression of CLEC4A1 mRNA

NCBI chr 4:157,845,811...157,857,926
Ensembl chr 4:157,845,752...157,858,273

G

C-type lectin domain family 4, member A3

increases expression

EXP

furan results in increased expression of CLEC4A3 mRNA

PMID:26194646 PMID:27387713

NCBI chr 4:157,885,899...157,896,728
Ensembl chr 4:157,885,895...157,896,727

G

C-type lectin domain family 4, member E

increases expression

EXP

furan results in increased expression of CLEC4E mRNA

NCBI chr 4:158,292,624...158,298,607
Ensembl chr 4:158,293,311...158,298,467

G

C-type lectin domain containing 7A

increases expression

ISO

furan results in increased expression of CLEC7A mRNA

NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:164,588,754...164,599,919

G

C-type lectin domain containing 9A

increases expression

EXP

furan results in increased expression of CLEC9A mRNA

NCBI chr 4:164,546,323...164,561,380
Ensembl chr 4:164,546,311...164,561,380

G

clathrin heavy chain linker domain containing 1

increases expression

EXP

furan results in increased expression of CLHC1 mRNA

NCBI chr14:107,488,983...107,529,667
Ensembl chr14:107,488,643...107,529,669

G

chloride intracellular channel 1

increases expression

EXP

furan results in increased expression of CLIC1 mRNA

NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367

G

chloride intracellular channel 2

increases expression

EXP

furan results in increased expression of CLIC2 mRNA

NCBI chr20:154,630...169,655
Ensembl chr20:154,255...169,648

G

chloride intracellular channel 5

increases expression

EXP

furan results in increased expression of CLIC5 mRNA

NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780

G

CAP-GLY domain containing linker protein 2

increases expression
decreases methylation

EXP

furan results in increased expression of CLIP2 mRNA
furan results in decreased methylation of CLIP2 gene

NCBI chr12:27,798,289...27,863,486
Ensembl chr12:27,799,524...27,863,484

G

clock circadian regulator

increases expression

ISO

furan results in increased expression of CLOCK mRNA

NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872

G

caseinolytic mitochondrial matrix peptidase chaperone subunit X

increases methylation

EXP

furan results in increased methylation of CLPX gene

NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762

G

clarin 3

increases expression

EXP

furan results in increased expression of CLRN3 mRNA

NCBI chr 1:199,748,863...199,764,486
Ensembl chr 1:199,748,864...199,764,486

G

clathrin, light chain B

increases methylation

EXP

furan results in increased methylation of CLTB gene

NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915

G

clusterin

increases expression

EXP

furan results in increased expression of CLU mRNA

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860

G

chymase 1

increases expression

EXP

furan results in increased expression of CMA1 mRNA

NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133

G

cytidine monophospho-N-acetylneuraminic acid hydroxylase

increases methylation
increases expression

EXP

furan results in increased methylation of CMAH gene
furan results in increased expression of CMAH mRNA

PMID:22079235 PMID:27387713

NCBI chr17:40,985,129...41,070,317
Ensembl chr17:41,011,641...41,070,252

G

cms1 ribosomal small subunit homolog

increases expression

EXP

furan results in increased expression of CMSS1 mRNA

NCBI chr11:56,403,620...56,701,751
Ensembl chr11:56,403,499...56,701,755

G

CKLF-like MARVEL transmembrane domain containing 3

decreases methylation
increases expression

EXP

furan results in decreased methylation of CMTM3 gene
furan results in increased expression of CMTM3 mRNA

NCBI chr19:629,000...637,152
Ensembl chr19:628,895...636,225

G

cardiomyopathy associated 5

decreases expression

EXP

furan results in decreased expression of CMYA5 mRNA

NCBI chr 2:26,014,545...26,113,273
Ensembl chr 2:26,014,177...26,113,376

G

connector enhancer of kinase suppressor of Ras 1

increases expression

EXP

furan results in increased expression of CNKSR1 mRNA

NCBI chr 5:151,731,222...151,742,049
Ensembl chr 5:151,731,224...151,742,203

G

chondromodulin

increases methylation

EXP

furan results in increased methylation of CNMD gene

NCBI chr15:61,450,617...61,475,382
Ensembl chr15:61,450,450...61,475,350

G

cyclin and CBS domain divalent metal cation transport mediator 1

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of CNNM1 gene
furan results in increased expression of CNNM1 mRNA

PMID:22079235 PMID:24183702 PMID:37517673

NCBI chr 1:252,245,377...252,304,205
Ensembl chr 1:252,245,623...252,304,205

G

CCR4-NOT transcription complex, subunit 7

increases methylation

EXP

furan results in increased methylation of CNOT7 gene

NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046

G

canopy FGF signaling regulator 2

increases methylation

EXP

furan results in increased methylation of CNPY2 gene

NCBI chr 7:1,332,293...1,338,081
Ensembl chr 7:1,334,335...1,340,333

G

cannabinoid receptor 1

increases methylation

EXP

furan results in increased methylation of CNR1 gene

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

ciliary neurotrophic factor

decreases expression

EXP

furan results in decreased expression of CNTF mRNA

NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488

G

contactin associated protein 1

increases methylation
decreases expression

EXP

furan results in increased methylation of CNTNAP1 gene
furan results in decreased expression of CNTNAP1 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:86,610,140...86,625,896
Ensembl chr10:86,611,890...86,631,730

G

component of oligomeric golgi complex 6

increases methylation

EXP

furan results in increased methylation of COG6 gene

NCBI chr 2:139,212,459...139,249,505
Ensembl chr 2:139,211,678...139,249,737

G

collagen type XI alpha 1 chain

increases expression

EXP

furan results in increased expression of COL11A1 mRNA

NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:204,509,136...204,702,264

G

collagen type XIV alpha 1 chain

increases expression

EXP

furan results in increased expression of COL14A1 mRNA

NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938

G

collagen type XV alpha 1 chain

increases expression

EXP

furan results in increased expression of COL15A1 mRNA

NCBI chr 5:66,297,546...66,403,172
Ensembl chr 5:66,297,461...66,403,170

G

collagen type XVI alpha 1 chain

increases expression
decreases methylation

EXP

furan results in increased expression of COL16A1 mRNA
furan results in decreased methylation of COL16A1 gene

NCBI chr 5:147,672,559...147,727,007
Ensembl chr 5:147,672,601...147,727,011

G

collagen type XVII alpha 1 chain

increases expression

EXP

furan results in increased expression of COL17A1 mRNA

NCBI chr 1:256,472,648...256,518,857
Ensembl chr 1:256,472,648...256,518,851

G

collagen type I alpha 1 chain

increases expression

EXP

furan results in increased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

increases expression

EXP

furan results in increased expression of COL1A2 mRNA

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type XXII alpha 1 chain

decreases expression

EXP

furan results in decreased expression of COL22A1 mRNA

NCBI chr 7:105,619,776...105,857,246
Ensembl chr 7:105,619,757...105,856,960

G

collagen type II alpha 1 chain

increases expression

EXP

furan results in increased expression of COL2A1 mRNA

NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627

G

collagen type III alpha 1 chain

increases expression

EXP

furan results in increased expression of COL3A1 mRNA

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type IV alpha 1 chain

increases expression

EXP

furan results in increased expression of COL4A1 mRNA

PMID:26194646 PMID:27387713

NCBI chr16:84,885,597...84,996,482
Ensembl chr16:84,885,597...84,996,482

G

collagen type V alpha 1 chain

decreases methylation
increases expression

EXP

furan results in decreased methylation of COL5A1 gene
furan results in increased expression of COL5A1 mRNA

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

increases expression

EXP

furan results in increased expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type V alpha 3 chain

increases expression

ISO
EXP

furan results in increased expression of COL5A3 mRNA

PMID:24183702 PMID:27387713

NCBI chr 8:27,580,768...27,626,002
Ensembl chr 8:27,580,768...27,626,122

G

collagen type VI alpha 2 chain

increases expression

EXP

furan results in increased expression of COL6A2 mRNA

NCBI chr20:12,021,182...12,048,932
Ensembl chr20:12,021,265...12,057,042

G

collagen type VII alpha 1 chain

increases expression

EXP

furan results in increased expression of COL7A1 mRNA

NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439

G

collagen type VIII alpha 1 chain

increases expression

EXP

furan results in increased expression of COL8A1 mRNA

NCBI chr11:56,245,998...56,378,586
Ensembl chr11:56,369,868...56,376,229

G

collectin sub-family member 12

increases expression

EXP

furan results in increased expression of COLEC12 mRNA

NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297

G

collagen beta(1-O)galactosyltransferase 1

increases methylation

EXP

furan results in increased methylation of COLGALT1 gene

NCBI chr16:18,353,779...18,366,087
Ensembl chr16:18,353,570...18,366,086

G

copper metabolism domain containing 1

increases methylation

EXP

furan results in increased methylation of COMMD1 gene

NCBI chr14:101,081,667...101,185,738
Ensembl chr14:101,081,667...101,185,639

G

COMM domain containing 10

increases methylation

EXP

furan results in increased methylation of COMMD10 gene

NCBI chr18:41,927,802...42,061,384
Ensembl chr18:41,921,694...42,086,729

G

cartilage oligomeric matrix protein

increases expression

EXP

furan results in increased expression of COMP mRNA

PMID:25539665 PMID:26194646

NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605

G

catechol-O-methyltransferase

decreases expression

EXP

furan results in decreased expression of COMT mRNA

NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533

G

COPI coat complex subunit zeta 2

increases methylation

EXP

furan results in increased methylation of COPZ2 gene

NCBI chr10:82,328,888...82,341,959
Ensembl chr10:82,328,660...82,341,959

G

coenzyme Q10A

decreases expression

EXP

furan results in decreased expression of COQ10A mRNA

NCBI chr 7:1,376,591...1,387,694
Ensembl chr 7:1,376,591...1,382,722

G

coenzyme Q4

increases expression

EXP

furan results in increased expression of COQ4 mRNA

NCBI chr 3:33,457,834...33,468,387
Ensembl chr 3:33,457,596...33,468,379

G

coenzyme Q6 monooxygenase

increases methylation

EXP

furan results in increased methylation of COQ6 gene

NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310

G

coenzyme Q8A

increases methylation

EXP

furan results in increased methylation of COQ8A gene

NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378

G

corin, serine peptidase

increases expression

EXP

furan results in increased expression of CORIN mRNA

NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649

G

coronin 6

increases expression

EXP

furan results in increased expression of CORO6 mRNA

NCBI chr10:62,808,172...62,817,788
Ensembl chr10:62,809,689...62,817,787

G

cytochrome c oxidase copper chaperone COX11

increases methylation

EXP

furan results in increased methylation of COX11 gene

NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,955,783...75,963,489

G

cytochrome c oxidase subunit 6A2

increases expression

EXP

furan results in increased expression of COX6A2 mRNA

NCBI chr 1:192,218,970...192,221,188
Ensembl chr 1:192,218,970...192,219,716

G

cytochrome c oxidase subunit VIc, pseudogene

increases expression

EXP

furan results in increased expression of COX6C-PS1 mRNA

NCBI chr19:69,090,047...69,090,905
Ensembl chr19:69,090,047...69,090,905

G

cytochrome c oxidase subunit 7A1

decreases expression

ISO

furan results in decreased expression of COX7A1 mRNA

NCBI chr 1:94,549,663...94,572,330
Ensembl chr 1:94,569,216...94,570,889

G

cytochrome c oxidase subunit 7B

increases methylation

EXP

furan results in increased methylation of COX7B gene

NCBI chr X:75,149,036...75,155,285
Ensembl chr X:75,148,996...75,155,284

G

cytochrome c oxidase subunit 7C

increases methylation

EXP

furan results in increased methylation of COX7C gene

NCBI chr 2:18,577,145...18,579,170
Ensembl chr 2:18,577,149...18,579,170

G

ceruloplasmin

decreases expression

EXP

furan results in decreased expression of CP mRNA

PMID:15120968 PMID:26194646

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

carboxypeptidase A1

increases methylation
decreases expression

EXP

furan results in increased methylation of CPA1 gene
furan results in decreased expression of CPA1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 4:60,224,801...60,230,928
Ensembl chr 4:60,224,801...60,230,928

G

carboxypeptidase A3

increases expression

EXP

furan results in increased expression of CPA3 mRNA

NCBI chr 2:104,641,619...104,673,253
Ensembl chr 2:104,641,621...104,673,237

G

carboxypeptidase B2

decreases expression

EXP

furan results in decreased expression of CPB2 mRNA

NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962

G

carboxypeptidase E

decreases methylation
increases expression

EXP

furan results in decreased methylation of CPE gene
furan results in increased expression of CPE mRNA

NCBI chr16:29,796,707...29,908,647
Ensembl chr16:29,796,689...29,909,524

G

cytoplasmic polyadenylation element binding protein 4

increases methylation
decreases expression

EXP

furan results in increased methylation of CPEB4 gene
furan results in decreased expression of CPEB4 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:16,222,271...16,284,248
Ensembl chr10:16,225,672...16,283,787

G

complexin 1

increases expression

EXP

furan results in increased expression of CPLX1 mRNA

NCBI chr14:1,329,073...1,360,781
Ensembl chr14:1,329,032...1,360,769

G

carboxypeptidase M

increases expression
decreases methylation

EXP

furan results in increased expression of CPM mRNA
furan results in decreased methylation of CPM gene

NCBI chr 7:55,111,599...55,172,114
Ensembl chr 7:55,111,599...55,172,114

G

carboxypeptidase N subunit 2

increases methylation
decreases expression

EXP

furan results in increased methylation of CPN2 gene
furan results in decreased expression of CPN2 mRNA

PMID:22079235 PMID:25539665

NCBI chr11:83,990,943...84,000,821
Ensembl chr11:83,990,940...84,001,059

G

copine 6

decreases expression

EXP

furan results in decreased expression of CPNE6 mRNA

NCBI chr15:32,968,047...32,975,008
Ensembl chr15:32,968,046...32,975,007

G

copine 8

decreases expression

EXP

furan results in decreased expression of CPNE8 mRNA

NCBI chr 7:123,494,864...123,669,060
Ensembl chr 7:123,494,865...123,669,060

G

copine family member 9

increases expression

EXP

furan results in increased expression of CPNE9 mRNA

NCBI chr 4:147,985,900...148,009,987
Ensembl chr 4:147,986,452...148,009,986

G

carboxypeptidase Q

increases methylation
decreases expression

EXP

furan results in increased methylation of CPQ gene
furan results in decreased expression of CPQ mRNA; furan results in decreased expression of PGCP mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137

G

cleavage and polyadenylation specific factor 4-like

decreases expression

ISO

furan results in decreased expression of CPSF4L mRNA

NCBI chr10:99,241,187...99,255,207
Ensembl chr10:99,242,794...99,257,172

G

carboxypeptidase X (M14 family), member 1

decreases methylation
increases expression

EXP

furan results in decreased methylation of CPXM1 gene
furan results in increased expression of CPXM1 mRNA

NCBI chr 3:138,041,645...138,048,443
Ensembl chr 3:138,041,645...138,048,857

G

carboxypeptidase X (M14 family), member 2

increases expression

EXP

furan results in increased expression of CPXM2 mRNA

NCBI chr 1:196,266,930...196,377,350
Ensembl chr 1:196,266,930...196,377,347

G

carboxypeptidase Z

decreases methylation
increases expression

EXP

furan results in decreased methylation of CPZ gene
furan results in increased expression of CPZ mRNA

NCBI chr14:79,448,242...79,471,557
Ensembl chr14:79,448,139...79,471,556

G

cellular retinoic acid binding protein 2

increases expression

EXP

furan results in increased expression of CRABP2 mRNA

NCBI chr 2:175,714,862...175,719,208
Ensembl chr 2:175,707,312...175,728,385

G

CASP2 and RIPK1 domain containing adaptor with death domain

increases expression

EXP

furan results in increased expression of CRADD mRNA

NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:31,685,622...31,874,512

G

crumbs cell polarity complex component 2

increases methylation

EXP

furan results in increased methylation of CRB2 gene

NCBI chr 3:41,946,694...41,974,629
Ensembl chr 3:41,947,325...41,974,629

G

cAMP responsive element binding protein 1

increases methylation

EXP

furan results in increased methylation of CREB1 gene

NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339

G

cellular repressor of E1A-stimulated genes 2

increases expression

EXP

furan results in increased expression of CREG2 mRNA

NCBI chr 9:49,367,693...49,441,133
Ensembl chr 9:49,399,114...49,440,985

G

cAMP responsive element modulator

increases methylation
decreases expression

EXP

furan results in increased methylation of CREM gene
furan results in decreased expression of CREM mRNA

PMID:22079235 PMID:26194646

NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160

G

cysteine-rich protein 2

decreases expression

EXP

furan results in decreased expression of CRIP2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120

G

cysteine-rich secretory protein 2

increases methylation

EXP

furan results in increased methylation of CRISP2 gene

NCBI chr 9:27,604,024...27,628,520
Ensembl chr 9:27,604,257...27,629,870

G

cysteine-rich secretory protein LCCL domain containing 2

increases expression
decreases methylation

EXP

furan results in increased expression of CRISPLD2 mRNA
furan results in decreased methylation of CRISPLD2 gene

NCBI chr19:64,961,764...65,020,099
Ensembl chr19:64,961,771...65,020,349

G

cytokine receptor-like factor 1

increases expression

EXP

furan results in increased expression of CRLF1 mRNA

NCBI chr16:18,958,695...18,970,026
Ensembl chr16:18,957,956...18,969,970

G

cardiolipin synthase 1

increases methylation

EXP

furan results in increased methylation of CRLS1 gene

NCBI chr 3:140,572,680...140,591,543
Ensembl chr 3:140,572,716...140,591,599

G

carnitine O-octanoyltransferase

decreases expression

EXP

furan results in decreased expression of CROT mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064

G

C-reactive protein

increases methylation
decreases expression

EXP

furan results in increased methylation of CRP gene
furan results in decreased expression of CRP mRNA

PMID:15120968 PMID:22079235 PMID:25539665

NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514

G

cartilage acidic protein 1

increases methylation

EXP

furan results in increased methylation of CRTAC1 gene

NCBI chr 1:251,040,963...251,182,920
Ensembl chr 1:251,028,143...251,182,689

G

cartilage associated protein

decreases expression

EXP

furan results in decreased expression of CRTAP mRNA

NCBI chr 8:122,926,117...122,945,843
Ensembl chr 8:122,926,117...122,945,843

G

Crx opposite strand transcript 1

increases expression

EXP

furan results in increased expression of CRXOS1 mRNA

NCBI chr 1:85,705,982...85,708,806
Ensembl chr 1:85,706,012...85,708,813

G

cryptochrome circadian regulator 1

decreases expression

EXP

furan results in decreased expression of CRY1 mRNA

NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822

G

crystallin, alpha A

decreases expression

EXP

furan results in decreased expression of CRYAA mRNA

NCBI chr20:9,784,872...9,788,656
Ensembl chr20:9,784,857...9,788,654

G

crystallin, alpha B

increases expression

EXP

furan results in increased expression of CRYAB mRNA

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

crystallin beta-gamma domain containing 3

increases expression

EXP

furan results in increased expression of CRYBG3 mRNA

NCBI chr11:54,218,399...54,330,962
Ensembl chr11:54,208,444...54,330,960

G

crystallin, gamma B

increases methylation

EXP

furan results in increased methylation of CRYGB gene

NCBI chr 9:73,955,204...73,957,264
Ensembl chr 9:73,955,204...73,957,264

G

crystallin, gamma E

increases methylation

EXP

furan results in increased methylation of CRYGE gene

NCBI chr 9:73,923,661...73,926,258
Ensembl chr 9:73,923,661...73,927,011

G

crystallin, gamma N

increases methylation

EXP

furan results in increased methylation of CRYGN gene

NCBI chr 4:11,286,475...11,294,002
Ensembl chr 4:11,286,475...11,294,002

G

crystallin, lambda 1

increases expression

EXP

furan results in increased expression of CRYL1 mRNA

PMID:25539665 PMID:26194646

NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563

G

cysteine sulfinic acid decarboxylase

increases methylation
decreases expression

EXP
ISO

furan results in increased methylation of CSAD gene
furan results in decreased expression of CSAD mRNA

PMID:22079235 PMID:24183702 PMID:26194646

NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581

G

chromosome segregation 1 like

increases methylation

EXP

furan results in increased methylation of CSE1L gene

NCBI chr 3:176,060,183...176,097,909
Ensembl chr 3:176,060,215...176,108,734

G

colony stimulating factor 3 receptor

decreases expression
increases expression

EXP

furan results in decreased expression of CSF3R mRNA
furan results in increased expression of CSF3R mRNA

PMID:25539665 PMID:27387713

NCBI chr 5:143,583,126...143,604,382
Ensembl chr 5:143,583,213...143,602,411

G

CUB and Sushi multiple domains 1

increases expression

EXP

furan results in increased expression of CSMD1 mRNA

NCBI chr16:78,920,549...80,520,710
Ensembl chr16:78,921,002...80,519,944

G

casein beta

decreases methylation

EXP

furan results in decreased methylation of CSN2 gene

NCBI chr14:20,601,824...20,609,061
Ensembl chr14:20,601,824...20,609,060

G

casein kinase 1, delta

increases methylation

EXP

furan results in increased methylation of CSNK1D gene

NCBI chr10:106,713,497...106,754,953
Ensembl chr10:106,694,279...106,754,953

G

casein kinase 1, gamma 3

increases expression

ISO

furan results in increased expression of CSNK1G3 mRNA

NCBI chr18:49,497,839...49,584,828
Ensembl chr18:49,497,839...49,584,828

G

chondroitin sulfate proteoglycan 4

increases expression

EXP

furan results in increased expression of CSPG4 mRNA

NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:66,160,942...66,200,806

G

cysteine and serine rich nuclear protein 3

decreases expression

EXP

furan results in decreased expression of CSRNP3 mRNA

NCBI chr 3:70,906,587...71,102,596
Ensembl chr 3:70,906,380...71,094,009

G

cystatin C

increases expression

EXP

furan results in increased expression of CST3 mRNA

NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937

G

cystatin E/M

increases expression

EXP

furan results in increased expression of CST6 mRNA

PMID:25539665 PMID:27387713

NCBI chr 1:212,084,676...212,086,384
Ensembl chr 1:212,084,676...212,086,384

G

cleavage stimulation factor subunit 3

increases expression

ISO
EXP

furan results in increased expression of CSTF3 mRNA

PMID:24183702 PMID:25539665

NCBI chr 3:111,421,291...111,492,539
Ensembl chr 3:111,421,234...111,497,046

G

C-terminal binding protein 2

increases methylation
increases expression

EXP

furan results in increased methylation of CTBP2 gene
furan results in increased expression of CTBP2 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261

G

collagen triple helix repeat containing 1

increases expression

EXP

furan results in increased expression of CTHRC1 mRNA

PMID:26194646 PMID:27387713

NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654

G

catenin alpha 2

increases expression

EXP

furan results in increased expression of CTNNA2 mRNA

NCBI chr 4:110,852,265...112,001,351
Ensembl chr 4:110,852,265...112,001,365

G

CTP synthase 1

increases expression

EXP

furan results in increased expression of CTPS1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465

G

CTP synthase 2

increases expression

EXP

furan results in increased expression of CTPS2 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:35,277,658...35,418,505
Ensembl chr X:35,277,658...35,418,505

G

cathepsin E

increases expression

EXP

furan results in increased expression of CTSE mRNA

NCBI chr13:45,644,168...45,666,722
Ensembl chr13:45,644,147...45,666,722

G

cathepsin K

increases expression

EXP

furan results in increased expression of CTSK mRNA

NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582

G

cathepsin R

decreases expression

EXP

furan results in decreased expression of CTSR mRNA

NCBI chr17:3,527,990...3,536,753
Ensembl chr17:3,527,990...3,536,746

G

CTTNBP2 N-terminal like

increases expression

EXP

furan results in increased expression of CTTNBP2NL mRNA

NCBI chr 2:195,196,318...195,244,792
Ensembl chr 2:195,196,318...195,243,181

G

cortexin 3

decreases expression

EXP

furan results in decreased expression of CTXN3 mRNA

NCBI chr18:53,129,505...53,138,694
Ensembl chr18:53,129,489...53,138,693

G

CUE domain containing 2

increases methylation

EXP

furan results in increased methylation of CUEDC2 gene

NCBI chr 1:255,133,479...255,142,016
Ensembl chr 1:255,133,421...255,141,956

G

cullin 3

decreases methylation

EXP

furan results in decreased methylation of CUL3 gene

NCBI chr 9:89,040,987...89,118,775
Ensembl chr 9:89,040,987...89,118,427

G

cutA divalent cation tolerance homolog-like

increases methylation

EXP

furan results in increased methylation of CUTAL gene

NCBI chr 3:38,551,790...38,571,209
Ensembl chr 3:38,551,731...38,571,208

G

CWC15 spliceosome-associated protein

increases methylation

EXP

furan results in increased methylation of CWC15 gene

NCBI chr 8:19,586,900...19,597,817
Ensembl chr 2:77,747,121...77,747,856
Ensembl chr 8:77,747,121...77,747,856

G

cell wall biogenesis 43 C-terminal homolog

increases expression

EXP

furan results in increased expression of CWH43 mRNA

NCBI chr14:35,108,328...35,154,578
Ensembl chr14:35,108,338...35,154,863

G

C-X3-C motif chemokine ligand 1

increases expression
decreases methylation

EXP

furan results in increased expression of CX3CL1 mRNA
furan results in decreased methylation of CX3CL1 gene

NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999

G

coxsackie virus and adenovirus receptor-like 1

increases expression

EXP

furan results in increased expression of CXADRL1 mRNA

NCBI chr 8:108,444,792...108,470,345
Ensembl chr 8:108,444,792...108,470,345

G

C-X-C motif chemokine ligand 1

decreases expression

EXP

furan results in decreased expression of CXCL1 mRNA

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

decreases expression
increases expression

EXP
ISO

furan results in decreased expression of CXCL10 mRNA
furan results in increased expression of CXCL10 mRNA

PMID:15120968 PMID:20194422 PMID:24183702 PMID:37517673

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 11

increases methylation

EXP

furan results in increased methylation of CXCL11 gene

NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567

G

C-X-C motif chemokine ligand 12

decreases expression
increases expression

EXP

furan results in decreased expression of CXCL12 mRNA
furan results in increased expression of CXCL12 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 13

increases expression

EXP

furan results in increased expression of CXCL13 mRNA

NCBI chr14:13,912,858...13,917,920
Ensembl chr14:13,912,858...13,917,920

G

C-X-C motif chemokine ligand 16

increases expression

EXP

furan results in increased expression of CXCL16 mRNA

PMID:26194646 PMID:27387713

NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226

G

C-X-C motif chemokine ligand 2

increases expression

EXP

furan results in increased expression of CXCL2 mRNA

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine receptor 2

decreases expression

EXP

furan results in decreased expression of CXCR2 mRNA

NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602

G

C-X-C motif chemokine receptor 4

increases expression

EXP

furan results in increased expression of CXCR4 mRNA

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459

G

C-X-C motif chemokine receptor 6

increases expression

EXP

furan results in increased expression of CXCR6 mRNA

NCBI chr 8:132,311,834...132,317,001
Ensembl chr 8:132,306,600...132,322,498

G

similar to human chromosome X open reading frame 38

increases methylation

EXP

furan results in increased methylation of CXHXORF38 gene

NCBI chr X:12,800,935...12,823,632
Ensembl chr X:12,802,377...12,814,198

G

cytochrome b-561

increases expression

ISO
EXP

furan results in increased expression of CYB561 mRNA

PMID:24183702 PMID:26194646

NCBI chr10:91,377,866...91,388,548
Ensembl chr10:91,377,866...91,385,097

G

cytochrome b-245 alpha chain

increases expression
decreases methylation

EXP

furan results in increased expression of CYBA mRNA
furan results in decreased methylation of CYBA gene

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytoglobin

increases expression

EXP

furan results in increased expression of CYGB mRNA

NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272

G

CYLD lysine 63 deubiquitinase

increases methylation

EXP

furan results in increased methylation of CYLD gene

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 11, subfamily a, polypeptide 1

increases expression

EXP

furan results in increased expression of CYP11A1 mRNA

PMID:24632374 PMID:25539665

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196

G

cytochrome P450, family 11, subfamily b, polypeptide 2

increases expression

EXP

furan results in increased expression of CYP11B1 mRNA

NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763

G

cytochrome P450, family 1, subfamily a, polypeptide 2

decreases expression

EXP

furan results in decreased expression of CYP1A2 mRNA

NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

EXP

furan results in increased expression of CYP1B1 mRNA

NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142

G

cytochrome P450, family 26, subfamily b, polypeptide 1

increases expression
decreases methylation

EXP

furan results in increased expression of CYP26B1 mRNA
furan results in decreased methylation of CYP26B1 gene

PMID:25539665 PMID:27387713

NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

EXP

furan results in increased expression of CYP27A1 mRNA

NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215

G

cytochrome P450, family 2, subfamily a, polypeptide 2

decreases expression

EXP

furan results in decreased expression of CYP2A2 mRNA

NCBI chr 1:91,391,492...91,417,158
Ensembl chr 1:91,391,502...91,417,158

G

cytochrome P450, family 2, subfamily a, polypeptide 3

increases expression

ISO

furan results in increased expression of CYP2A4 mRNA

PMID:24183702 PMID:37517673

NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649

G

cytochrome P450, subfamily 2, polypeptide 11

decreases expression

EXP

furan results in decreased expression of CYP2C mRNA; furan results in decreased expression of CYP2C11 mRNA

PMID:15120968 PMID:25539665

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853

G

cytochrome P450, family 2, subfamily c, polypeptide 12

decreases expression
increases expression

EXP

furan results in decreased expression of CYP2C12 mRNA
furan results in increased expression of CYP2C12 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 1:248,619,887...248,681,945
Ensembl chr 1:248,619,882...248,677,042

G

cytochrome P450, family 2, subfamily c, polypeptide 23

increases methylation

EXP

furan results in increased methylation of CYP2C23 gene

NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067

G

cytochrome P450, family 2, subfamily c, polypeptide 24

increases expression

EXP

furan results in increased expression of CYP2C24 mRNA; furan results in increased expression of CYP2C55 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607

G

cytochrome P450, family 2, subfamily C, polypeptide 6

decreases expression

EXP
ISO

furan results in decreased expression of CYP2C6 mRNA
furan results in decreased expression of CYP2C29 mRNA

PMID:20194422 PMID:25539665 PMID:26194646

NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798

G

cytochrome P450, family 2, subfamily c, polypeptide 7

decreases expression

EXP

furan results in decreased expression of CYP2C7 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 1:247,966,295...248,022,393
Ensembl chr 1:247,966,346...248,022,388

G

cytochrome P450, family 2, subfamily c, polypeptide 79

decreases expression

EXP

furan results in decreased expression of CYP2C79 mRNA

G

cytochrome P450, family 2, subfamily d, polypeptide 1

decreases expression

EXP

furan results in decreased expression of CYP2D1 mRNA

NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479

G

cytochrome P450, family 2, subfamily d, polypeptide 2

increases methylation
decreases expression

EXP

furan results in increased methylation of CYP2D2 gene
furan results in decreased expression of CYP2D2 mRNA

PMID:22079235 PMID:25539665

NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281

G

cytochrome P450, family 2, subfamily d, polypeptide 3

decreases expression

EXP

furan results in decreased expression of CYP2D3 mRNA

NCBI chr 7:115,797,785...115,802,142
Ensembl chr 7:115,797,789...115,802,158

G

cytochrome P450, family 2, subfamily d, polypeptide 4

decreases expression

EXP

furan results in decreased expression of CYP2D4 mRNA

NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837

G

cytochrome P450, family 2, subfamily d, polypeptide 5

decreases expression

EXP

furan results in decreased expression of CYP2D5 mRNA

NCBI chr 7:115,779,981...115,784,554

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression
multiple interactions
increases expression

EXP
ISO

furan results in decreased expression of CYP2E1 mRNA; furan results in decreased expression of CYP2E1 protein
rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein]
1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde

PMID:15120968 PMID:20124500 PMID:21842885 PMID:34450210

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily g, polypeptide 1

decreases expression

ISO

furan results in decreased expression of CYP2G1 mRNA

PMID:24183702 PMID:37517673

NCBI chr 1:91,273,309...91,284,499
Ensembl chr 1:91,272,680...91,284,498

G

cytochrome P450, family 2, subfamily j, polypeptide 10

increases expression

EXP

furan results in increased expression of CYP2J10 mRNA

NCBI chr 5:116,076,012...116,110,914
Ensembl chr 5:116,023,198...116,110,897

G

cytochrome P450, family 3, subfamily a, polypeptide 18

decreases expression

EXP

furan results in decreased expression of CYP3A18 mRNA

NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788

G

cytochrome P450, family 3, subfamily a, polypeptide 2

decreases expression

EXP

furan results in decreased expression of CYP3A2 mRNA

PMID:25539665 PMID:26194646

NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857

G

cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1

decreases expression

EXP

furan results in decreased expression of CYP3A23-3A1 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813

G

cytochrome P450, family 3, subfamily a, polypeptide 62

increases expression

EXP

furan results in increased expression of CYP3A62 mRNA

PMID:25539665 PMID:26194646

NCBI chr12:21,511,763...21,547,598
Ensembl chr12:21,471,542...21,547,598

G

cytochrome P450, family 3, subfamily a, polypeptide 73

decreases expression

EXP

furan results in decreased expression of CYP3A73 mRNA

PMID:25539665 PMID:26194646

NCBI chr12:14,069,393...14,108,893
Ensembl chr12:14,070,257...14,094,400

G

cytochrome P450, family 46, subfamily a, polypeptide 1

increases methylation

EXP

furan results in increased methylation of CYP46A1 gene

NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971

G

cytochrome P450, family 4, subfamily a, polypeptide 1

decreases expression

EXP

furan results in decreased expression of CYP4A1 mRNA

PMID:15120968 PMID:26194646

NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231

G

cytochrome P450, family 4, subfamily a, polypeptide 2

decreases expression

EXP

furan results in decreased expression of CYP4A2 mRNA

NCBI chr 5:134,160,356...134,170,908
Ensembl chr 5:134,160,358...134,176,156

G

cytochrome P450, family 4, subfamily a, polypeptide 8

decreases expression

EXP

furan results in decreased expression of CYP4A8 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:133,938,882...133,970,226
Ensembl chr 5:133,938,883...133,970,226

G

cytochrome P450, family 4, subfamily f, polypeptide 4

decreases expression

EXP

furan results in decreased expression of CYP4F4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:12,367,711...12,384,010
Ensembl chr 7:12,367,660...12,384,010

G

cytochrome P450, family 4, subfamily f, polypeptide 5

increases expression

EXP

furan results in increased expression of CYP4F5 mRNA

NCBI chr 7:12,194,567...12,209,495
Ensembl chr 7:12,195,022...12,209,965

G

cytochrome P450, family 4, subfamily x, polypeptide 1

increases methylation

EXP

furan results in increased methylation of CYP4X1 gene

NCBI chr 5:133,888,439...133,923,254
Ensembl chr 5:133,888,439...133,919,642

G

cytochrome P450, family 51

increases expression

ISO

furan results in increased expression of CYP51 mRNA

NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450

G

cytochrome P450 family 7 subfamily A member 1

decreases expression
multiple interactions
increases expression

EXP
ISO

furan results in decreased expression of CYP7A1 mRNA
rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA]
furan results in increased expression of CYP7A1 mRNA

PMID:15120968 PMID:25539665 PMID:32251705 PMID:38160780

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

cytochrome P450 family 7 subfamily B member 1

increases expression

EXP

furan results in increased expression of CYP7B1 mRNA

NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804

G

CYFIP related Rac1 interactor A

increases expression

EXP

furan results in increased expression of CYRIA mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:40,774,165...40,883,005
Ensembl chr 6:40,774,171...40,881,860

G

cystin 1

increases expression

EXP

furan results in increased expression of CYS1 mRNA

NCBI chr 6:47,029,440...47,046,671
Ensembl chr 6:47,028,461...47,046,671

G

cytohesin 3

increases methylation

EXP

furan results in increased methylation of CYTH3 gene

NCBI chr12:15,953,781...16,076,584
Ensembl chr12:15,953,791...16,047,506

G

cytokine like 1

decreases expression

EXP

furan results in decreased expression of CYTL1 mRNA

NCBI chr14:77,278,635...77,283,645
Ensembl chr14:77,278,636...77,283,645

G

cysteine and tyrosine rich 1

increases expression

EXP

furan results in increased expression of CYYR1 mRNA

PMID:25539665 PMID:26194646

NCBI chr11:38,044,003...38,150,391
Ensembl chr11:38,001,699...38,164,473

G

DAB adaptor protein 1

decreases expression

EXP

furan results in decreased expression of DAB1 mRNA

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584

G

DAB adaptor protein 2

increases expression

EXP

furan results in increased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888

G

dishevelled-binding antagonist of beta-catenin 3

increases expression

EXP

furan results in increased expression of DACT3 mRNA

NCBI chr 1:86,674,989...86,686,722
Ensembl chr 1:86,674,734...86,687,421

G

diacylglycerol lipase, alpha

increases expression

EXP

furan results in increased expression of DAGLA mRNA

NCBI chr 1:216,315,515...216,372,219
Ensembl chr 1:216,315,516...216,372,111

G

D-amino-acid oxidase

increases methylation

EXP

furan results in increased methylation of DAO gene

NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300

G

death-associated protein kinase 3

increases methylation

EXP

furan results in increased methylation of DAPK3 gene

NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:9,174,904...9,183,272

G

death associated protein-like 1

increases methylation
increases expression

EXP

furan results in increased methylation of DAPL1 gene
furan results in increased expression of DAPL1 mRNA

PMID:22079235 PMID:25539665 PMID:27387713

NCBI chr 3:64,369,734...64,389,677
Ensembl chr 3:64,369,546...64,389,677

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

increases methylation

EXP

furan results in increased methylation of DAPP1 gene

NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:229,099,319...229,148,843

G

drebrin 1

increases expression

EXP

furan results in increased expression of DBN1 mRNA

NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,155,787...9,170,122

G

D-box binding PAR bZIP transcription factor

increases expression

EXP

furan results in increased expression of DBP mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205

G

dephospho-CoA kinase domain containing

increases methylation
increases expression

EXP

furan results in increased methylation of DCAKD gene
furan results in increased expression of DCAKD mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr10:88,457,829...88,489,011
Ensembl chr10:88,457,829...88,480,118

G

doublecortin domain containing 2

increases expression

EXP

furan results in increased expression of DCDC2 mRNA

PMID:26194646 PMID:27387713

NCBI chr17:40,274,009...40,459,757
Ensembl chr17:40,274,009...40,458,790

G

dachsous cadherin-related 1

increases expression

EXP

furan results in increased expression of DCHS1 mRNA

NCBI chr 1:169,516,758...169,550,789
Ensembl chr 1:169,516,762...169,536,639

G

deoxycytidine kinase

increases expression

EXP

furan results in increased expression of DCK mRNA

NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,589,298...19,610,326

G

doublecortin-like kinase 1

increases expression

EXP

furan results in increased expression of DCLK1 mRNA

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090

G

doublecortin-like kinase 2

increases expression

EXP

furan results in increased expression of DCLK2 mRNA

NCBI chr 2:174,506,660...174,636,353
Ensembl chr 2:174,506,660...174,636,192

G

doublecortin-like kinase 3

decreases expression

ISO

furan results in decreased expression of DCLK3 mRNA

NCBI chr 8:120,279,916...120,332,362
Ensembl chr 8:120,279,757...120,332,432

G

decorin

increases expression

EXP

furan results in increased expression of DCN mRNA

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926

G

dCMP deaminase

increases expression

EXP

furan results in increased expression of DCTD mRNA

NCBI chr16:50,799,699...50,831,398
Ensembl chr16:50,787,875...50,831,186

G

dCTP pyrophosphatase 1

increases expression

EXP

furan results in increased expression of DCTPP1 mRNA

NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:191,307,935...191,313,405

G

defective in cullin neddylation 1 domain containing 1

decreases expression

EXP

furan results in decreased expression of DCUN1D1 mRNA

NCBI chr 2:120,649,445...120,700,879
Ensembl chr 2:120,649,445...120,700,870

G

dimethylarginine dimethylaminohydrolase 1

increases expression

EXP

furan results in increased expression of DDAH1 mRNA

NCBI chr 2:237,327,812...237,460,624
Ensembl chr 2:237,327,766...237,460,626

G

DDAH family member 2, ADMA-independent

increases expression

EXP

furan results in increased expression of DDAH2 mRNA

NCBI chr20:3,766,115...3,769,161
Ensembl chr20:3,766,120...3,769,183

G

dopa decarboxylase

decreases expression

EXP

furan results in decreased expression of DDC mRNA

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806

G

DNA-damage inducible transcript 3

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of DDIT3 mRNA
rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of DDIT3 protein]
furan results in increased expression of DDIT3 mRNA; furan results in increased expression of DDIT3 protein

PMID:15120968 PMID:34450210

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4-like

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of DDIT4L gene
furan results in increased expression of DDIT4L mRNA

PMID:22079235 PMID:24183702 PMID:25539665 PMID:37517673

NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225

G

discoidin domain receptor tyrosine kinase 1

increases methylation

EXP

furan results in increased methylation of DDR1 gene

NCBI chr20:3,047,269...3,069,277
Ensembl chr20:3,050,375...3,069,276

G

discoidin domain receptor tyrosine kinase 2

increases expression

EXP

furan results in increased expression of DDR2 mRNA

NCBI chr13:84,726,412...84,851,032
Ensembl chr13:84,731,180...84,850,288

G

DEAD-box helicase 17

increases methylation

EXP

furan results in increased methylation of DDX17 gene

NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747

G

DExD-box helicase 21

increases expression

ISO

furan results in increased expression of DDX21 mRNA

NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238

G

DExD-box helicase 39A

increases methylation

EXP

furan results in increased methylation of DDX39A gene

NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306

G

DExD-box helicase 50

increases methylation

EXP

furan results in increased methylation of DDX50 gene

NCBI chr20:31,104,354...31,133,652
Ensembl chr20:31,104,354...31,133,652

G

differentially expressed in FDCP 8 homolog

increases methylation

EXP

furan results in increased methylation of DEF8 gene

NCBI chr19:68,383,293...68,404,133
Ensembl chr19:68,383,349...68,404,125

G

defensin alpha 24

increases expression

EXP

furan results in increased expression of DEFA24 mRNA

NCBI chr16:77,052,014...77,053,046
Ensembl chr16:77,052,014...77,053,046

G

defensin beta 14

increases expression

EXP

furan results in increased expression of DEFB14 mRNA

NCBI chr16:77,365,892...77,369,668
Ensembl chr16:77,365,892...77,366,880

G

defensin beta 17

decreases expression

EXP

furan results in decreased expression of DEFB17 mRNA

NCBI chr 9:28,376,792...28,380,421
Ensembl chr 9:28,376,792...28,380,421

G

defensin beta 40

decreases methylation

EXP

furan results in decreased methylation of DEFB40 gene

NCBI chr16:77,526,834...77,529,918
Ensembl chr16:77,526,834...77,529,918

G

defensin beta 51

decreases expression

EXP

furan results in decreased expression of DEFB51 mRNA

NCBI chr16:77,273,373...77,277,495
Ensembl chr16:77,273,373...77,277,495

G

delta(4)-desaturase, sphingolipid 2

increases expression
decreases methylation

EXP

furan results in increased expression of DEGS2 mRNA
furan results in decreased methylation of DEGS2 gene

NCBI chr 6:133,360,449...133,377,677
Ensembl chr 6:133,360,457...133,364,422

G

DEK proto-oncogene

increases methylation

EXP

furan results in increased methylation of DEK gene

NCBI chr17:17,786,989...17,809,096
Ensembl chr17:17,787,139...17,810,122

G

DAP3 binding cell death enhancer 1

increases methylation

EXP

furan results in increased methylation of DELE1 gene

NCBI chr18:30,325,369...30,349,285
Ensembl chr18:30,336,308...30,349,938

G

DENN domain containing 2D

increases expression

EXP

furan results in increased expression of DENND2D mRNA

NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397

G

DEP domain containing 1

increases expression

EXP

furan results in increased expression of DEPDC1 mRNA

NCBI chr 2:251,343,250...251,376,709
Ensembl chr 2:251,343,281...251,376,709

G

DEP domain containing 1B

increases expression

EXP

furan results in increased expression of DEPDC1B mRNA

NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202

G

DEP domain containing 7

increases methylation

EXP

furan results in increased methylation of DEPDC7 gene

NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:111,554,706...111,575,979

G

derlin 3

decreases expression

EXP

furan results in decreased expression of DERL3 mRNA

NCBI chr20:12,753,926...12,766,478
Ensembl chr20:12,762,981...12,766,477

G

desmin

increases expression

EXP

furan results in increased expression of DES mRNA

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347

G

desumoylating isopeptidase 2

increases expression

ISO

furan results in increased expression of DESI2 mRNA

NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981

G

24-dehydrocholesterol reductase

increases methylation

EXP

furan results in increased methylation of DHCR24 gene

NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936

G

dehydrodolichyl diphosphate synthase subunit

increases expression

EXP

furan results in increased expression of DHDDS mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129

G

dehydrogenase/reductase 7

decreases expression

EXP

furan results in decreased expression of DHRS7 mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744

G

dehydrogenase E1 and transketolase domain containing 1

increases methylation

EXP

furan results in increased methylation of DHTKD1 gene

NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071

G

DEAH-box helicase 38

decreases methylation

EXP

furan results in decreased methylation of DHX38 gene

NCBI chr19:54,422,418...54,439,434
Ensembl chr19:54,422,418...54,439,423

G

death inducer-obliterator 1

increases expression

ISO

furan results in increased expression of DIDO1 mRNA

NCBI chr 3:188,150,100...188,203,445
Ensembl chr 3:188,150,100...188,194,823

G

iodothyronine deiodinase 1

increases methylation
decreases expression

EXP

furan results in increased methylation of DIO1 gene
furan results in decreased expression of DIO1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771

G

iodothyronine deiodinase 3

increases expression

EXP

furan results in increased expression of DIO3 mRNA

NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:135,107,074...135,107,985

G

disco-interacting protein 2 homolog C

increases methylation

EXP

furan results in increased methylation of DIP2C gene

NCBI chr17:65,338,711...65,724,111
Ensembl chr17:65,338,711...65,723,344

G

divergent protein kinase domain 1A

decreases expression

ISO

furan results in decreased expression of DIPK1A mRNA

NCBI chr14:1,917,353...1,988,188
Ensembl chr14:1,917,324...1,988,678

G

divergent protein kinase domain 1B

increases expression

EXP

furan results in increased expression of DIPK1B mRNA

NCBI chr 3:29,852,710...29,862,248
Ensembl chr 3:29,853,973...29,862,255

G

divergent protein kinase domain 2A

decreases expression

EXP

furan results in decreased expression of DIPK2A mRNA

NCBI chr 8:103,950,345...103,969,461
Ensembl chr 8:103,909,931...103,969,461

G

DISC1 scaffold protein

increases methylation

EXP

furan results in increased methylation of DISC1 gene

NCBI chr19:69,911,548...70,120,970
Ensembl chr19:69,911,976...70,120,970

G

dispatched RND transporter family member 1

increases expression

EXP

furan results in increased expression of DISP1 mRNA

NCBI chr13:97,252,574...97,398,329
Ensembl chr13:97,252,574...97,398,460

G

dickkopf WNT signaling pathway inhibitor 3

increases expression

EXP

furan results in increased expression of DKK3 mRNA

NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186

G

DLG associated protein 5

increases expression

EXP

furan results in increased expression of DLGAP5 mRNA

NCBI chr15:23,113,678...23,144,281
Ensembl chr15:23,113,678...23,144,176

G

delta like non-canonical Notch ligand 1

increases expression

EXP

furan results in increased expression of DLK1 protein

NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:134,192,518...134,200,529

G

delta like canonical Notch ligand 1

increases expression
decreases expression

ISO
EXP

furan results in increased expression of DLL1 mRNA
furan results in decreased expression of DLL1 mRNA

PMID:24183702 PMID:25539665

NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:64,985,161...64,993,276

G

DNA methyltransferase 1-associated protein 1

increases methylation

EXP

furan results in increased methylation of DMAP1 gene

NCBI chr 5:136,380,211...136,388,229
Ensembl chr 5:136,380,216...136,388,219

G

diencephalon/mesencephalon homeobox 1

increases expression

EXP

furan results in increased expression of DMBX1 mRNA

NCBI chr 5:134,630,968...134,639,781
Ensembl chr 5:134,630,968...134,639,781

G

dimethylglycine dehydrogenase

increases methylation

EXP

furan results in increased methylation of DMGDH gene

NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071

G

Dmx-like 1

increases methylation

EXP

furan results in increased methylation of DMXL1 gene

NCBI chr18:45,179,505...45,349,999
Ensembl chr18:45,179,551...45,356,406

G

dynein axonemal assembly factor 19

increases expression

EXP

furan results in increased expression of CCDC103 mRNA

NCBI chr10:88,346,453...88,349,853
Ensembl chr10:88,346,453...88,349,853

G

dynein axonemal assembly factor 4

increases expression

EXP

furan results in increased expression of DNAAF4 mRNA

NCBI chr 8:82,577,044...82,601,653
Ensembl chr 8:82,578,755...82,592,205

G

dynein axonemal assembly factor 9

increases methylation

EXP

furan results in increased methylation of DNAAF9 gene

NCBI chr 3:138,370,971...138,505,711
Ensembl chr 3:138,372,531...138,505,695

G

dynein axonemal intermediate chain 4

increases methylation

EXP

furan results in increased methylation of DNAI4 gene

NCBI chr 5:123,016,480...123,105,283
Ensembl chr 5:123,016,480...123,105,283

G

dynein axonemal intermediate chain 7

increases expression

EXP

furan results in increased expression of DNAI7 mRNA

NCBI chr 4:179,874,338...179,910,716
Ensembl chr 4:179,873,522...179,910,780

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

ISO

furan results in increased expression of DNAJA1 mRNA

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

DnaJ heat shock protein family (Hsp40) member A3

increases expression

EXP

furan results in increased expression of DNAJA3 mRNA

NCBI chr10:11,361,168...11,386,599
Ensembl chr10:11,361,168...11,386,599

G

DnaJ heat shock protein family (Hsp40) member B11

decreases expression

ISO

furan results in decreased expression of DNAJB11 mRNA

NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800

G

DnaJ heat shock protein family (Hsp40) member B3

increases methylation
decreases methylation
increases expression

EXP

furan results in increased methylation of DNAJB3 gene
furan results in decreased methylation of DNAJB3 gene
furan results in increased expression of DNAJB3 mRNA

PMID:22079235 PMID:27387713

NCBI chr 9:96,243,345...96,244,358
Ensembl chr 9:96,243,071...96,244,408

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

ISO

furan results in increased expression of DNAJB4 mRNA

NCBI chr 2:243,790,296...243,819,042
Ensembl chr 2:243,790,297...243,819,042

G

DnaJ heat shock protein family (Hsp40) member B5

decreases expression

EXP

furan results in decreased expression of DNAJB5 mRNA

NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:61,972,706...61,981,860

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

EXP

furan results in increased expression of DNAJB9 mRNA

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C14

increases methylation

EXP

furan results in increased methylation of DNAJC14 gene

NCBI chr 7:1,818,360...1,831,642
Ensembl chr 7:1,820,247...1,831,658

G

DnaJ heat shock protein family (Hsp40) member C18

increases methylation

EXP

furan results in increased methylation of DNAJC18 gene

NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535

G

DnaJ heat shock protein family (Hsp40) member C2

increases expression

EXP

furan results in increased expression of DNAJC2 mRNA

PMID:20562052 PMID:22079235

NCBI chr 4:14,162,490...14,189,662
Ensembl chr 4:14,163,838...14,192,846

G

DnaJ heat shock protein family (Hsp40) member C5 beta

increases expression

EXP

furan results in increased expression of DNAJC5B mRNA

NCBI chr 2:103,889,863...103,982,413
Ensembl chr 2:103,889,919...103,982,423

G

dynein, axonemal, light chain 1

increases expression

EXP

furan results in increased expression of DNAL1 mRNA

PMID:25539665 PMID:27387713

NCBI chr 6:109,478,941...109,515,201
Ensembl chr 6:109,478,858...109,513,148

G

dynein, axonemal, light intermediate chain 1

decreases expression

EXP

furan results in decreased expression of DNALI1 mRNA

NCBI chr 5:142,603,132...142,611,970
Ensembl chr 5:142,603,134...142,611,993

G

deoxyribonuclease 1

multiple interactions

ISO

[Bromodeoxyuridine co-treated with furan] affects the expression of DNASE1 mRNA

NCBI chr10:12,005,305...12,030,615
Ensembl chr10:12,005,306...12,010,497

G

deoxyribonuclease 2 beta

increases methylation

EXP

furan results in increased methylation of DNASE2B gene

NCBI chr 2:238,131,182...238,168,041
Ensembl chr 2:238,131,185...238,146,558

G

aspartyl aminopeptidase

increases expression

EXP

furan results in increased expression of DNPEP mRNA

NCBI chr 9:84,248,581...84,257,484
Ensembl chr 9:84,233,486...84,256,977

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

EXP

furan results in increased expression of DNPH1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631

G

dedicator of cytokinesis 2

decreases expression

EXP

furan results in decreased expression of DOCK2 mRNA

NCBI chr10:19,331,412...19,748,987
Ensembl chr10:19,331,412...19,748,969

G

docking protein 1

increases methylation

EXP

furan results in increased methylation of DOK1 gene

NCBI chr 4:117,095,171...117,098,251
Ensembl chr 4:117,095,175...117,097,825

G

docking protein 3

increases expression

EXP

furan results in increased expression of DOK3 mRNA

NCBI chr17:9,114,763...9,121,781
Ensembl chr17:9,114,762...9,120,335

G

docking protein 4

increases expression

EXP

furan results in increased expression of DOK4 mRNA

NCBI chr19:10,152,511...10,163,182
Ensembl chr19:10,152,458...10,164,190

G

dopamine receptor interacting protein 1

increases methylation

EXP

furan results in increased methylation of DORIP1 gene

NCBI chr 6:88,701,651...88,710,204
Ensembl chr 6:88,701,818...88,708,820

G

dipeptidase 1

increases expression

EXP

furan results in increased expression of DPEP1 mRNA

NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775

G

developmental pluripotency-associated 3

increases expression

EXP

furan results in increased expression of DPPA3 mRNA

NCBI chr 4:157,523,426...157,526,810
Ensembl chr 5:93,143,318...93,144,472
Ensembl chr 4:93,143,318...93,144,472

G

developmental pluripotency associated 5

increases expression

ISO

furan results in increased expression of DPPA5A mRNA

NCBI chr 8:88,095,627...88,097,936
Ensembl chr 1:14,260,684...14,261,146

G

dermatopontin

increases methylation
decreases expression

EXP

furan results in increased methylation of DPT gene
furan results in decreased expression of DPT mRNA

PMID:22079235 PMID:25539665

NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758

G

dpy-19 like C-mannosyltransferase 3

increases methylation

EXP

furan results in increased methylation of DPY19L3 gene

NCBI chr 1:97,487,206...97,554,232
Ensembl chr 1:97,487,206...97,554,232

G

dihydropyrimidine dehydrogenase

decreases expression

EXP

furan results in decreased expression of DPYD mRNA

NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778

G

dihydropyrimidinase-like 2

increases expression
decreases methylation

EXP

furan results in increased expression of DPYSL2 mRNA
furan results in decreased methylation of DPYSL2 gene

NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065

G

dihydropyrimidinase-like 4

increases expression

EXP

furan results in increased expression of DPYSL4 mRNA

NCBI chr 1:203,312,646...203,328,523
Ensembl chr 1:203,311,694...203,328,523

G

dihydropyrimidinase-like 5

decreases expression

EXP

furan results in decreased expression of DPYSL5 mRNA

NCBI chr 6:31,295,035...31,379,348
Ensembl chr 6:31,295,035...31,379,348

G

dynein regulatory complex subunit 3

increases expression

EXP

furan results in increased expression of DRC3 mRNA

NCBI chr10:45,620,045...45,698,902
Ensembl chr10:45,648,410...45,698,900

G

dopamine receptor D1

increases methylation

EXP

furan results in increased methylation of DRD1 gene

NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166

G

dopamine receptor D2

decreases expression

EXP

furan results in decreased expression of DRD2 mRNA

NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339

G

DSN1 component of MIS12 kinetochore complex

increases expression

EXP

furan results in increased expression of DSN1 mRNA

NCBI chr 3:166,072,775...166,089,029
Ensembl chr 3:166,074,033...166,085,890

G

dystrobrevin, beta

increases methylation

EXP

furan results in increased methylation of DTNB gene

NCBI chr 6:32,286,022...32,483,007
Ensembl chr 6:32,285,941...32,485,872

G

deltex E3 ubiquitin ligase 3L

increases methylation

EXP

furan results in increased methylation of DTX3L gene

NCBI chr11:78,320,225...78,329,837
Ensembl chr11:78,317,650...78,329,837

G

deoxythymidylate kinase

increases methylation

EXP

furan results in increased methylation of DTYMK gene

NCBI chr 9:101,762,899...101,771,733
Ensembl chr 9:101,762,899...101,774,504

G

dual oxidase 1

increases expression

EXP

furan results in increased expression of DUOX1 mRNA

NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187

G

dual oxidase 2

increases expression

EXP

furan results in increased expression of DUOX2 mRNA

NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203

G

dual oxidase maturation factor 1

increases expression

EXP

furan results in increased expression of DUOXA1 mRNA

NCBI chr 3:129,703,416...129,714,110
Ensembl chr 3:129,703,416...129,706,829

G

dual oxidase maturation factor 2

increases expression

EXP

furan results in increased expression of DUOXA2 mRNA

NCBI chr 3:129,698,938...129,702,656
Ensembl chr 3:129,698,092...129,702,656

G

dihydrouridine synthase 4-like

increases expression

EXP

furan results in increased expression of DUS4L mRNA

NCBI chr 6:53,955,609...53,970,050
Ensembl chr 6:53,955,609...53,970,087

G

dual specificity phosphatase 1

decreases expression

EXP

furan results in decreased expression of DUSP1 mRNA

NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644

G

dual specificity phosphatase 18

increases expression

EXP

furan results in increased expression of DUSP18 mRNA

NCBI chr14:83,013,850...83,035,168
Ensembl chr14:83,011,014...83,056,929

G

dual specificity phosphatase 26

decreases expression

EXP

furan results in decreased expression of DUSP26 mRNA

PMID:25539665 PMID:26194646

NCBI chr16:67,744,830...67,752,673
Ensembl chr16:67,744,842...67,752,101

G

dual specificity phosphatase 4

decreases expression

EXP

furan results in decreased expression of DUSP4 mRNA

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700

G

dual specificity phosphatase 6

multiple interactions
increases expression

ISO

[Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP6 mRNA
furan results in increased expression of DUSP6 mRNA

PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

dual specificity phosphatase 8

increases expression
multiple interactions

ISO

furan results in increased expression of DUSP8 mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of DUSP8 mRNA

PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441

G

dual specificity phosphatase 9

increases expression

EXP

furan results in increased expression of DUSP9 mRNA

NCBI chr X:156,503,237...156,507,162
Ensembl chr X:156,503,190...156,507,161

G

DPY30 domain containing 1

decreases expression

EXP

furan results in decreased expression of DYDC1 mRNA

NCBI chr16:16,975,029...16,995,550
Ensembl chr16:16,975,812...16,997,332

G

dynein cytoplasmic 2 light intermediate chain 1

increases expression

EXP

furan results in increased expression of DYNC2LI1 mRNA

PMID:25539665 PMID:27387713

NCBI chr 6:15,745,350...15,778,166
Ensembl chr 6:15,745,350...15,778,166

G

dynein light chain LC8-type 2

increases methylation

EXP

furan results in increased methylation of DYNLL2 gene

NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285

G

dynein light chain Tctex-type 1

increases expression

EXP

furan results in increased expression of DYNLT1 mRNA

NCBI chr 1:49,292,093...49,299,051
Ensembl chr 1:49,282,243...49,298,951

G

dynein light chain Tctex-type 2B

increases expression

EXP

furan results in increased expression of DYNLT2B mRNA

NCBI chr11:81,864,195...81,872,555
Ensembl chr11:81,864,195...81,872,555

G

E2F transcription factor 1

increases expression

EXP

furan results in increased expression of E2F1 mRNA

PMID:20562052 PMID:22079235

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

E2F transcription factor 3

increases expression

EXP

furan results in increased expression of E2F3 mRNA

NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725

G

ELL associated factor 2

increases expression

EXP

furan results in increased expression of EAF2 mRNA

NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993

G

Epstein-Barr virus induced 3

increases expression

EXP

furan results in increased expression of EBI3 mRNA

NCBI chr 9:861,441...874,731
Ensembl chr 9:870,792...874,973

G

EBP, cholestenol delta-isomerase

increases methylation

EXP

furan results in increased methylation of EBP gene

NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781

G

endothelin-converting enzyme 2

increases methylation

EXP

furan results in increased methylation of ECE2 gene

NCBI chr11:93,767,559...93,782,896
Ensembl chr11:93,767,559...93,793,292

G

ethylmalonyl-CoA decarboxylase 1

increases methylation

EXP

furan results in increased methylation of ECHDC1 gene

NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208

G

enoyl-CoA hydratase, short chain 1

affects binding
increases activity

EXP

furan binds to ECHS1 protein
furan results in increased activity of ECHS1 protein

PMID:22240984 PMID:27402187

NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506

G

epithelial cell transforming 2

increases expression

ISO
EXP

furan results in increased expression of ECT2 mRNA

PMID:24183702 PMID:25539665 PMID:37517673

NCBI chr 2:111,904,522...111,966,786
Ensembl chr 2:111,904,522...111,966,626

G

epididymal protein 3B

decreases expression

EXP

furan results in decreased expression of EDDM3B mRNA

NCBI chr15:26,817,508...26,820,274
Ensembl chr15:26,786,199...26,820,294

G

endothelial differentiation-related factor 1

increases methylation

EXP

furan results in increased methylation of EDF1 gene

NCBI chr 3:28,764,906...28,779,499

G

endothelin 1

increases expression

EXP

furan results in increased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

endothelin receptor type A

decreases expression
increases expression

EXP

furan results in decreased expression of EDNRA mRNA
furan results in increased expression of EDNRA mRNA

PMID:25539665 PMID:27387713

NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284

G

EEF1A lysine methyltransferase 1

increases methylation

EXP

furan results in increased methylation of EEF1AKMT1 gene

NCBI chr15:35,809,842...35,826,921
Ensembl chr15:35,809,842...35,827,129

G

endonuclease/exonuclease/phosphatase family domain containing 1

increases methylation
decreases expression

EXP

furan results in increased methylation of EEPD1 gene
furan results in decreased expression of EEPD1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 8:32,233,834...32,340,148
Ensembl chr 8:32,233,070...32,340,147

G

EGF containing fibulin extracellular matrix protein 1

increases expression

EXP

furan results in increased expression of EFEMP1 mRNA

NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808

G

EGF containing fibulin extracellular matrix protein 2

increases expression

EXP

furan results in increased expression of EFEMP2 mRNA

NCBI chr 1:212,211,057...212,218,739
Ensembl chr 1:212,210,972...212,218,739

G

EF-hand domain containing 1

increases expression

EXP

furan results in increased expression of EFHC1 mRNA

NCBI chr 9:30,872,238...30,910,703
Ensembl chr 9:30,871,565...30,910,703

G

EF-hand domain containing 2

increases expression

EXP

furan results in increased expression of EFHC2 mRNA

NCBI chr X:7,943,603...8,144,073
Ensembl chr X:7,943,725...8,144,215

G

ephrin A1

decreases expression

EXP

furan results in decreased expression of EFNA1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726

G

ephrin A2

increases expression

EXP

furan results in increased expression of EFNA2 mRNA

NCBI chr 7:10,167,091...10,177,719
Ensembl chr 7:10,167,091...10,177,719

G

ephrin B1

increases methylation

EXP

furan results in increased methylation of EFNB1 gene

NCBI chr X:68,297,529...68,310,335
Ensembl chr X:68,297,492...68,349,546

G

ephrin B2

decreases expression

EXP

furan results in decreased expression of EFNB2 mRNA

NCBI chr16:87,485,215...87,529,224
Ensembl chr16:87,485,198...87,529,208

G

ephrin B3

increases methylation

EXP

furan results in increased methylation of EFNB3 gene

NCBI chr10:54,773,282...54,780,727
Ensembl chr10:54,773,282...54,797,651

G

embryonal Fyn-associated substrate

increases expression

EXP

furan results in increased expression of EFS mRNA

NCBI chr15:32,362,401...32,374,490
Ensembl chr15:32,361,843...32,371,743

G

epidermal growth factor receptor

decreases expression

EXP

furan results in decreased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

early growth response 1

decreases expression

ISO

furan results in decreased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

early growth response 2

increases methylation
increases expression

EXP

furan results in increased methylation of EGR2 gene
furan results in increased expression of EGR2 mRNA

PMID:22079235 PMID:27387713

NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748

G

EH-domain containing 4

decreases methylation
increases expression

EXP

furan results in decreased methylation of EHD4 gene
furan results in increased expression of EHD4 mRNA

NCBI chr 3:127,511,973...127,575,856
Ensembl chr 3:127,511,954...127,576,072

G

ets homologous factor

decreases methylation

EXP

furan results in decreased methylation of EHF gene

NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:110,096,756...110,134,928

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

decreases expression

EXP

furan results in decreased expression of EHHADH mRNA

NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662

G

EP300 interacting inhibitor of differentiation 1

decreases expression

EXP

furan results in decreased expression of EID1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 3:133,376,389...133,378,108
Ensembl chr 3:133,370,474...133,378,434

G

eukaryotic translation initiation factor 2B subunit beta

increases expression

EXP

furan results in increased expression of EIF2B2 mRNA

NCBI chr 6:110,597,979...110,604,403
Ensembl chr 6:110,597,729...110,604,403

G

eukaryotic translation initiation factor 3, subunit B

increases methylation

EXP

furan results in increased methylation of EIF3B gene

NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939

G

eukaryotic translation initiation factor 4A1

increases methylation

EXP

furan results in increased methylation of EIF4A1 gene

NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602

G

eukaryotic translation initiation factor 4B

increases expression

EXP

furan results in increased expression of EIF4B mRNA

NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

EXP

furan results in increased expression of EIF4EBP1 mRNA

NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874

G

eukaryotic translation initiation factor 5

increases methylation

EXP

furan results in increased methylation of EIF5 gene

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

eukaryotic translation initiation factor 5A2

increases expression

EXP

furan results in increased expression of EIF5A2 mRNA

NCBI chr 2:113,656,748...113,674,598
Ensembl chr 2:113,657,797...113,674,594

G

elaC ribonuclease Z 1

increases methylation
decreases expression

EXP
ISO

furan results in increased methylation of ELAC1 gene
furan results in decreased expression of ELAC1 mRNA

PMID:22079235 PMID:24183702

NCBI chr18:69,596,475...69,617,206
Ensembl chr18:69,598,827...69,616,175

G

E74 like ETS transcription factor 3

increases methylation
increases expression

EXP

furan results in increased methylation of ELF3 gene
furan results in increased expression of ELF3 mRNA

PMID:22079235 PMID:27387713

NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380

G

ETS transcription factor ELK4

increases expression

EXP

furan results in increased expression of ELK4 mRNA

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199

G

elongation factor for RNA polymerase II 3

increases expression

EXP

furan results in increased expression of ELL3 mRNA

NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852

G

elastin

increases expression

EXP

furan results in increased expression of ELN mRNA

NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413

G

ELOVL fatty acid elongase 1

increases methylation

EXP

furan results in increased methylation of ELOVL1 gene

NCBI chr 5:137,246,781...137,251,351
Ensembl chr 5:137,246,849...137,251,352

G

ELOVL fatty acid elongase 2

increases expression

EXP

furan results in increased expression of ELOVL2 mRNA

NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601

G

ELOVL fatty acid elongase 3

decreases expression

ISO

furan results in decreased expression of ELOVL3 mRNA

NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:254,938,731...254,942,559

G

ELOVL fatty acid elongase 6

increases expression

EXP

furan results in increased expression of ELOVL6 mRNA

NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549

G

ELOVL fatty acid elongase 7

increases expression

EXP

furan results in increased expression of ELOVL7 mRNA

NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:41,522,738...41,592,020

G

ER membrane protein complex subunit 1

increases methylation

EXP

furan results in increased methylation of EMC1 gene

NCBI chr 5:156,891,773...156,917,092
Ensembl chr 5:156,891,773...156,917,092

G

ER membrane protein complex subunit 8

increases methylation

EXP

furan results in increased methylation of EMC8 gene

NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235

G

endomucin

increases expression

EXP

furan results in increased expression of EMCN mRNA

NCBI chr 2:228,564,445...228,644,370
Ensembl chr 2:228,564,430...228,645,155

G

essential meiotic structure-specific endonuclease 1

increases expression

EXP

furan results in increased expression of EME1 mRNA

NCBI chr10:80,083,585...80,092,450
Ensembl chr10:80,083,585...80,092,301

G

EMAP like 5

decreases expression

EXP

furan results in decreased expression of EML5 mRNA

NCBI chr 6:123,775,269...123,905,585
Ensembl chr 6:123,776,368...123,905,538

G

epithelial membrane protein 1

increases expression

EXP

furan results in increased expression of EMP1 mRNA

PMID:26194646 PMID:27387713

NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365

G

epithelial membrane protein 2

decreases expression
increases expression

ISO
EXP

furan results in decreased expression of EMP2 mRNA
furan results in increased expression of EMP2 mRNA

PMID:24183702 PMID:27387713

NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532

G

empty spiracles homeobox 2

increases expression

EXP

furan results in increased expression of EMX2 mRNA

NCBI chr 1:268,612,663...268,619,671
Ensembl chr 1:268,612,663...268,619,671

G

ENAH, actin regulator

increases expression

EXP

furan results in increased expression of ENAH mRNA

NCBI chr13:96,149,437...96,269,841
Ensembl chr13:96,149,437...96,269,796

G

ectodermal-neural cortex 1

increases expression

ISO
EXP

furan results in increased expression of ENC1 mRNA

PMID:24183702 PMID:26194646

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721

G

enolase 1

increases expression
affects activity
affects binding

EXP

furan results in increased expression of ENO1 mRNA
furan affects the activity of ENO1 protein
furan binds to ENO1 protein

PMID:15120968 PMID:22240984 PMID:27402187

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

enolase 2

increases expression

EXP

furan results in increased expression of ENO2 mRNA

NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220

G

enolase-phosphatase 1

increases methylation

EXP

furan results in increased methylation of ENOPH1 gene

NCBI chr14:9,835,626...9,862,051
Ensembl chr14:9,835,627...9,873,668

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

increases methylation
decreases expression

EXP

furan results in increased methylation of ENPP2 gene
furan results in decreased expression of ENPP2 mRNA

PMID:22079235 PMID:27387713

NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957

G

ectonucleotide pyrophosphatase/phosphodiesterase 4

increases expression

EXP

furan results in increased expression of ENPP4 mRNA

NCBI chr 9:24,386,351...24,396,248
Ensembl chr 9:24,360,272...24,396,152

G

ectonucleoside triphosphate diphosphohydrolase 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of ENTPD2 gene
furan results in increased expression of ENTPD2 mRNA

NCBI chr 3:28,611,722...28,617,237
Ensembl chr 3:28,611,772...28,618,184

G

ectonucleoside triphosphate diphosphohydrolase 4

increases methylation
decreases expression

EXP

furan results in increased methylation of ENTPD4 gene
furan results in decreased expression of ENTPD4 mRNA

PMID:22079235 PMID:25539665

NCBI chr15:51,040,665...51,068,450
Ensembl chr15:51,040,673...51,068,441

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

ISO

furan results in increased expression of ENTPD5 mRNA

NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495

G

ectonucleoside triphosphate diphosphohydrolase 6

increases methylation

EXP

furan results in increased methylation of ENTPD6 gene

NCBI chr 3:160,036,055...160,058,580
Ensembl chr 3:160,036,121...160,059,451

G

ectonucleoside triphosphate diphosphohydrolase 8

increases methylation

EXP

furan results in increased methylation of ENTPD8 gene

NCBI chr 3:28,283,392...28,295,686
Ensembl chr 3:28,285,777...28,293,686

G

ENY2, transcription and export complex 2 subunit

decreases methylation

EXP

furan results in decreased methylation of ENY2 gene

NCBI chr 7:77,465,885...77,489,637
Ensembl chr 7:77,466,119...77,491,057

G

endothelium and lymphocyte associated ASCH domain 2

increases methylation

EXP

furan results in increased methylation of EOLA2 gene

NCBI chr X:154,108,628...154,113,426
Ensembl chr X:154,108,836...154,113,436

G

E1A binding protein p300

decreases expression

EXP

furan results in decreased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

endothelial PAS domain protein 1

increases expression

ISO

furan results in increased expression of EPAS1 mRNA

NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729

G

erythrocyte membrane protein band 4.1 like 4A

increases expression

EXP

furan results in increased expression of EPB41L4A mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498

G

epithelial cell adhesion molecule

increases expression
decreases methylation

EXP

furan results in increased expression of EPCAM mRNA
furan results in decreased methylation of EPCAM gene

PMID:26194646 PMID:27387713 PMID:38160780

NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702

G

ependymin related 1

increases expression

EXP

furan results in increased expression of EPDR1 mRNA

NCBI chr17:50,029,591...50,054,254
Ensembl chr17:50,029,256...50,054,250

G

Eph receptor A3

increases expression

EXP

furan results in increased expression of EPHA3 mRNA

NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425

G

Eph receptor A4

decreases expression

EXP

furan results in decreased expression of EPHA4 mRNA

NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755

G

Eph receptor A8

increases expression

EXP

furan results in increased expression of EPHA8 mRNA

NCBI chr 5:154,449,566...154,476,966
Ensembl chr 5:154,449,566...154,476,966

G

Eph receptor B3

increases expression
decreases methylation

EXP

furan results in increased expression of EPHB3 mRNA
furan results in decreased methylation of EPHB3 gene

NCBI chr11:93,345,098...93,363,775
Ensembl chr11:93,345,098...93,363,775

G

Eph receptor B6

decreases expression

EXP

furan results in decreased expression of EPHB6 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:71,458,971...71,476,659

G

epoxide hydrolase 1

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of EPHX1 gene
furan results in increased expression of EPHX1 mRNA

PMID:22079235 PMID:24183702 PMID:25539665 PMID:26194646 PMID:37517673

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

epoxide hydrolase 2

decreases expression

ISO

furan results in decreased expression of EPHX2 mRNA

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

epoxide hydrolase 3

increases methylation

EXP

furan results in increased methylation of EPHX3 gene

NCBI chr 7:11,857,367...11,862,674
Ensembl chr 7:11,857,367...11,862,674

G

epsin 3

increases expression

EXP

furan results in increased expression of EPN3 mRNA

NCBI chr10:79,935,857...79,946,121
Ensembl chr10:79,935,857...79,944,235

G

epiplakin 1

increases expression

EXP

furan results in increased expression of EPPK1 mRNA

NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468

G

EPS8 signaling adaptor L3

increases expression

EXP

furan results in increased expression of EPS8L3 mRNA

NCBI chr 2:198,202,862...198,216,255
Ensembl chr 2:198,200,486...198,216,255

G

epithelial stromal interaction 1

increases methylation

EXP

furan results in increased methylation of EPSTI1 gene

NCBI chr15:59,692,712...59,791,376
Ensembl chr15:59,693,142...59,791,380

G

eosinophil peroxidase

increases methylation

EXP

furan results in increased methylation of EPX gene

NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180

G

erb-b2 receptor tyrosine kinase 2

increases expression

EXP

furan results in increased expression of ERBB2 mRNA

NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

EXP

furan results in increased expression of ERCC1 mRNA

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120

G

Ets2 repressor factor

decreases expression

EXP

furan results in decreased expression of ERF mRNA

NCBI chr 1:89,957,760...89,966,213
Ensembl chr 1:89,957,760...89,966,213

G

glutamate-rich 5

increases expression

EXP

furan results in increased expression of ERICH5 mRNA

NCBI chr 7:67,538,154...67,569,433
Ensembl chr 7:67,536,588...67,563,989

G

glutamate-rich 6

decreases expression

EXP

furan results in decreased expression of ERICH6 mRNA

NCBI chr 2:145,001,833...145,027,935
Ensembl chr 2:145,001,833...145,028,223

G

ER lipid raft associated 1

decreases expression

EXP

furan results in decreased expression of ERLIN1 mRNA

NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions
increases phosphorylation

ISO

rhodioloside inhibits the reaction [furan results in increased phosphorylation of ERN1 protein]

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791

G

ERBB receptor feedback inhibitor 1

increases methylation
decreases expression

EXP

furan results in increased methylation of ERRFI1 gene
furan results in decreased expression of ERRFI1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

establishment of sister chromatid cohesion N-acetyltransferase 2

increases expression

EXP

furan results in increased expression of ESCO2 mRNA

NCBI chr15:44,210,124...44,230,785
Ensembl chr15:44,210,641...44,231,304
Ensembl chr15:44,210,641...44,231,304

G

extra spindle pole bodies like 1, separase

increases expression

EXP

furan results in increased expression of ESPL1 mRNA

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570

G

espin

increases methylation
increases expression

EXP

furan results in increased methylation of ESPN gene
furan results in increased expression of ESPN mRNA

PMID:22079235 PMID:27387713

NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984

G

estrogen receptor 1

increases expression

ISO

furan results in increased expression of ESR1 mRNA

NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354

G

epithelial splicing regulatory protein 1

increases expression

EXP

furan results in increased expression of ESRP1 mRNA

NCBI chr 5:29,224,831...29,279,381
Ensembl chr 5:29,225,360...29,279,278

G

estrogen-related receptor gamma

increases methylation

EXP

furan results in increased methylation of ESRRG gene

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877

G

electron transfer flavoprotein subunit alpha

affects binding

EXP

furan binds to ETFA protein

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080

G

electron transfer flavoprotein subunit beta lysine methyltransferase

increases expression

EXP

furan results in increased expression of ETFBKMT mRNA

NCBI chr 4:183,871,819...183,936,843
Ensembl chr 4:183,871,827...183,881,621

G

ETS variant transcription factor 3

decreases expression

EXP

furan results in decreased expression of ETV3 mRNA

NCBI chr 2:175,263,389...175,278,217
Ensembl chr 2:175,263,459...175,278,208

G

ETS variant transcription factor 4

increases methylation

EXP

furan results in increased methylation of ETV4 gene

NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318

G

ETS variant transcription factor 6

decreases expression

EXP

furan results in decreased expression of ETV6 mRNA

NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802

G

eva-1 homolog B

increases methylation

EXP

furan results in increased methylation of EVA1B gene

NCBI chr 5:143,711,627...143,716,963
Ensembl chr 5:143,711,395...143,717,551

G

eva-1 homolog C

increases expression

EXP

furan results in increased expression of EVA1C mRNA

NCBI chr11:43,575,613...43,649,677
Ensembl chr11:43,576,332...43,649,834

G

EvC ciliary complex subunit 1

decreases expression

ISO

furan results in decreased expression of EVC mRNA

NCBI chr14:77,680,901...77,722,608
Ensembl chr14:77,680,943...77,723,100

G

exonuclease 1

increases expression

EXP

furan results in increased expression of EXO1 mRNA

PMID:22079235 PMID:22507866

NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861

G

exostosin-like glycosyltransferase 1

decreases expression

EXP

furan results in decreased expression of EXTL1 mRNA

NCBI chr 5:151,857,629...151,872,830
Ensembl chr 5:151,857,629...151,872,830

G

EYA transcriptional coactivator and phosphatase 3

increases methylation

EXP

furan results in increased methylation of EYA3 gene

NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:150,137,256...150,218,852

G

ezrin

increases expression

EXP

furan results in increased expression of EZR mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573

G

coagulation factor X

increases methylation
decreases expression

EXP

furan results in increased methylation of F10 gene
furan results in decreased expression of F10 mRNA

PMID:22079235 PMID:25539665

NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280

G

coagulation factor XII

increases methylation
decreases expression

EXP

furan results in increased methylation of F12 gene
furan results in decreased expression of F12 mRNA

PMID:22079235 PMID:25539665

NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664

G

coagulation factor II, thrombin

decreases expression

EXP

furan results in decreased expression of F2 mRNA

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246

G

F2R like trypsin receptor 1

increases expression

EXP

furan results in increased expression of F2RL1 mRNA

NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954

G

coagulation factor III, tissue factor

increases expression

EXP

furan results in increased expression of F3 mRNA

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

coagulation factor V

increases methylation
decreases expression

EXP

furan results in increased methylation of F5 gene
furan results in decreased expression of F5 mRNA

PMID:22079235 PMID:25539665

NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247

G

coagulation factor VII

increases methylation
decreases expression

EXP

furan results in increased methylation of F7 gene
furan results in decreased expression of F7 mRNA

PMID:22079235 PMID:26194646

NCBI chr16:83,191,896...83,202,775
Ensembl chr16:83,191,914...83,202,738

G

coagulation factor VIII

increases methylation

EXP

furan results in increased methylation of F8 gene

NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683

G

coagulation factor IX

decreases expression

EXP

furan results in decreased expression of F9 mRNA

PMID:25539665 PMID:26194646

NCBI chr X:143,388,642...143,433,143
Ensembl chr X:143,388,621...143,433,146

G

fatty acid binding protein 1

affects binding

EXP

furan binds to FABP1 protein

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113

G

fatty acid binding protein 12

increases expression

ISO

furan results in increased expression of FABP12 mRNA

NCBI chr 2:93,446,966...93,462,393
Ensembl chr 2:93,407,956...93,462,390

G

fatty acid binding protein 2

increases expression

EXP

furan results in increased expression of FABP2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:213,724,629...213,728,686
Ensembl chr 2:213,724,629...213,728,686

G

fatty acid binding protein 3

decreases expression

ISO

furan results in decreased expression of FABP3 mRNA

NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881

G

fatty acid binding protein 4

increases expression

EXP

furan results in increased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972

G

fatty acid binding protein 5

increases expression

EXP

furan results in increased expression of FABP5 mRNA

PMID:20124500 PMID:25539665

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127

G

fatty acid binding protein 7

decreases expression

EXP

furan results in decreased expression of FABP7 mRNA

PMID:25539665 PMID:26194646

NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907

G

fatty acid desaturase 3

increases expression

EXP

furan results in increased expression of FADS3 mRNA

NCBI chr 1:216,110,547...216,127,431
Ensembl chr 1:216,110,201...216,141,758

G

fatty acid desaturase 6

increases methylation
decreases expression

EXP

furan results in increased methylation of FADS6 gene
furan results in decreased expression of FADS6 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:101,020,921...101,037,281
Ensembl chr10:101,021,960...101,037,160

G

fumarylacetoacetate hydrolase

increases methylation

EXP

furan results in increased methylation of FAH gene

NCBI chr 1:147,957,931...147,980,708
Ensembl chr 1:147,957,935...147,981,046

G

fumarylacetoacetate hydrolase domain containing 1

decreases expression

EXP

furan results in decreased expression of FAHD1 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:14,378,058...14,379,497
Ensembl chr10:14,378,120...14,379,867

G

fumarylacetoacetate hydrolase domain containing 2A

increases methylation

EXP

furan results in increased methylation of FAHD2A gene

NCBI chr 3:135,110,480...135,118,653
Ensembl chr 3:135,109,482...135,118,853

G

Fas apoptotic inhibitory molecule

increases expression

EXP

furan results in increased expression of FAIM mRNA

PMID:20562052 PMID:22079235

NCBI chr 8:108,423,259...108,445,365
Ensembl chr 8:108,423,221...108,440,151

G

Fas apoptotic inhibitory molecule 2

decreases expression

EXP

furan results in decreased expression of FAIM2 mRNA

NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:132,512,210...132,538,026

G

family with sequence similarity 110, member C

increases expression

EXP

furan results in increased expression of FAM110C mRNA

NCBI chr 6:53,366,013...53,372,270
Ensembl chr 6:53,352,870...53,401,117

G

FAM111 trypsin like peptidase A

increases expression

EXP

furan results in increased expression of FAM111A mRNA

NCBI chr 1:219,065,542...219,081,213
Ensembl chr 1:219,065,601...219,081,211

G

family with sequence similarity 118, member B

increases methylation

EXP

furan results in increased methylation of FAM118B gene

NCBI chr 8:41,824,522...41,875,190
Ensembl chr 8:41,824,158...41,846,256

G

family with sequence similarity 120 member B

increases methylation

EXP

furan results in increased methylation of FAM120B gene

NCBI chr 1:64,993,104...65,058,160
Ensembl chr 1:65,012,060...65,058,160

G

family with sequence similarity 13, member A

increases expression

EXP

furan results in increased expression of FAM13A mRNA

NCBI chr 4:89,386,685...89,485,940
Ensembl chr 4:89,388,569...89,485,988

G

family with sequence similarity 13, member B

increases expression

ISO

furan results in increased expression of FAM13B mRNA

NCBI chr18:26,314,440...26,395,260
Ensembl chr18:26,314,440...26,380,732

G

family with sequence similarity 162, member A

decreases expression

EXP

furan results in decreased expression of FAM162A mRNA

NCBI chr11:78,186,260...78,215,186
Ensembl chr11:78,185,852...78,216,560

G

family with sequence similarity 168, member A

decreases expression

EXP

furan results in decreased expression of FAM168A mRNA

NCBI chr 1:164,469,447...164,615,542
Ensembl chr 1:164,469,471...164,615,506

G

family with sequence similarity 174 member C

increases methylation

EXP

furan results in increased methylation of FAM174C gene

NCBI chr 7:10,182,653...10,184,363
Ensembl chr 7:10,182,653...10,184,363

G

family with sequence similarity 180, member A

increases expression

EXP

furan results in increased expression of FAM180A mRNA

PMID:26194646 PMID:27387713

NCBI chr 4:64,959,999...64,975,176
Ensembl chr 4:64,959,999...64,975,176

G

family with sequence similarity 187, member B

increases expression

ISO

furan results in increased expression of FAM187B mRNA

NCBI chr 1:95,329,482...95,346,940
Ensembl chr 1:95,332,631...95,371,536

G

family with sequence similarity 217, member B

decreases methylation

EXP

furan results in decreased methylation of FAM217B gene

NCBI chr 3:185,883,277...185,892,976
Ensembl chr 3:185,883,367...185,892,974

G

family with sequence similarity 229, member B

increases expression

EXP

furan results in increased expression of FAM229B mRNA

PMID:25539665 PMID:27387713

NCBI chr20:44,093,492...44,106,871
Ensembl chr20:44,093,493...44,106,871

G

family with sequence similarity 236 member D

decreases expression

EXP

furan results in decreased expression of FAM236D mRNA

NCBI chr X:71,978,105...71,978,873
Ensembl chr X:71,977,939...71,978,795

G

family with sequence similarity 25, member A

increases expression

EXP

furan results in increased expression of FAM25A mRNA

NCBI chr16:9,686,922...9,690,728
Ensembl chr16:9,686,922...9,690,728

G

FAM3 metabolism regulating signaling molecule B

increases expression

EXP

furan results in increased expression of FAM3B mRNA

NCBI chr11:50,300,926...50,333,296
Ensembl chr11:50,300,926...50,347,339

G

FAM3 metabolism regulating signaling molecule D

increases expression

EXP

furan results in increased expression of FAM3D mRNA

NCBI chr15:18,969,737...19,003,276
Ensembl chr15:18,969,737...19,004,701

G

family with sequence similarity 43, member A

increases expression

EXP

furan results in increased expression of FAM43A mRNA

NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297

G

family with sequence similarity 72, member A

increases expression

EXP

furan results in increased expression of FAM72A mRNA

NCBI chr13:45,519,940...45,531,322
Ensembl chr13:45,519,818...45,531,324

G

family with sequence similarity 83, member F

increases expression

EXP

furan results in increased expression of FAM83F mRNA

PMID:25539665 PMID:27387713

NCBI chr 7:114,091,356...114,120,640
Ensembl chr 7:114,091,335...114,120,638

G

family with sequence similarity 83, member G

increases expression

ISO

furan results in increased expression of FAM83G mRNA

NCBI chr10:46,862,983...46,887,499
Ensembl chr10:46,862,369...46,886,277

G

FA complementation group A

increases expression

EXP

furan results in increased expression of FANCA mRNA

NCBI chr19:68,210,562...68,271,080
Ensembl chr19:68,212,643...68,271,019

G

FA complementation group B

increases expression

EXP

furan results in increased expression of FANCB mRNA

NCBI chr X:33,035,387...33,051,993
Ensembl chr X:33,035,387...33,051,808

G

FA complementation group D2

increases expression

EXP

furan results in increased expression of FANCD2 mRNA

NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035

G

fibroblast activation protein, alpha

increases expression

EXP

furan results in increased expression of FAP mRNA

NCBI chr 3:67,547,398...67,616,271
Ensembl chr 3:67,546,921...67,617,601

G

FERM, ARH/RhoGEF and pleckstrin domain protein 2

decreases expression

EXP

furan results in decreased expression of FARP2 mRNA

NCBI chr 9:101,501,061...101,609,092
Ensembl chr 9:101,501,102...101,609,086

G

Fas cell surface death receptor

increases expression

EXP

furan results in increased expression of FAS mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

Fas ligand

increases expression

EXP

furan results in increased expression of FASLG mRNA

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503

G

fatty acid synthase

decreases expression

EXP

furan results in decreased expression of FASN mRNA

NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583

G

Fas-activated serine/threonine kinase

increases methylation

EXP

furan results in increased methylation of FASTK gene; furan results in increased methylation of FASTK promoter

NCBI chr 4:11,624,697...11,628,769
Ensembl chr 4:11,624,689...11,629,867

G

Fas binding factor 1

increases expression

ISO

furan results in increased expression of FBF1 mRNA

PMID:24183702 PMID:37517673

NCBI chr10:101,874,661...101,900,497
Ensembl chr10:101,874,664...101,900,738

G

filamin binding LIM protein 1

increases expression

EXP

furan results in increased expression of FBLIM1 mRNA

NCBI chr 5:159,167,004...159,198,578
Ensembl chr 5:159,167,004...159,196,853

G

fibrillarin-like 1

increases methylation

EXP

furan results in increased methylation of FBLL1 gene

NCBI chr10:20,762,716...20,764,359
Ensembl chr10:20,761,581...20,764,670

G

fibulin 1

increases expression

EXP

furan results in increased expression of FBLN1 mRNA

NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965

G

fibulin 5

increases expression

EXP

furan results in increased expression of FBLN5 mRNA

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

fibrillin 1

increases expression

EXP

furan results in increased expression of FBN1 mRNA

NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283

G

fructose-bisphosphatase 1

affects binding

EXP

furan binds to FBP1 protein

NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746

G

fructose-bisphosphatase 2

increases methylation
increases expression

EXP

furan results in increased methylation of FBP2 gene
furan results in increased expression of FBP2 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366

G

F-box and leucine-rich repeat protein 22

increases expression

EXP

furan results in increased expression of FBXL22 mRNA

NCBI chr 8:75,965,027...75,971,714
Ensembl chr 8:75,965,027...75,971,714

G

F-box and leucine-rich repeat protein 8

increases expression

EXP

furan results in increased expression of FBXL8 mRNA

NCBI chr19:50,048,221...50,057,191
Ensembl chr19:50,052,393...50,057,453

G

F-box protein 21

decreases expression

ISO

furan results in decreased expression of FBXO21 mRNA

NCBI chr12:44,231,918...44,266,035
Ensembl chr12:44,231,923...44,266,035

G

F-box protein 28

increases methylation

EXP

furan results in increased methylation of FBXO28 gene

NCBI chr13:96,527,667...96,553,138
Ensembl chr13:96,527,670...96,553,138

G

F-box protein 31

decreases expression

ISO

furan results in decreased expression of FBXO31 mRNA

NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674

G

F-box protein 36

increases expression

EXP

furan results in increased expression of FBXO36 mRNA

NCBI chr 9:93,490,618...93,555,298
Ensembl chr 9:93,489,865...93,555,305

G

F-box protein 5

increases methylation

EXP

furan results in increased methylation of FBXO5 gene

NCBI chr 1:44,601,412...44,607,781
Ensembl chr 1:44,601,412...44,607,781

G

F-box protein 7

increases methylation

EXP

furan results in increased methylation of FBXO7 gene

NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180

G

F-box and WD-40 domain protein 17

increases expression

EXP

furan results in increased expression of FBXW17 mRNA

NCBI chr17:14,511,173...14,529,021
Ensembl chr17:14,511,194...14,530,275

G

Fc epsilon receptor Ia

increases expression

EXP

furan results in increased expression of FCER1A mRNA

NCBI chr13:88,218,427...88,224,723
Ensembl chr13:88,218,420...88,224,681

G

Fcf1 rRNA-processing protein

increases methylation

EXP

furan results in increased methylation of FCF1 gene

NCBI chr 6:110,348,854...110,360,715
Ensembl chr 6:110,348,845...110,372,221

G

Fc gamma binding protein

increases expression

EXP

furan results in increased expression of FCGBP mRNA

NCBI chr 1:92,502,461...92,540,658
Ensembl chr 1:92,499,498...92,540,658

G

Fc fragment of IgG binding protein-like 1

increases expression

EXP

furan results in increased expression of FCGBPL1 mRNA

NCBI chr 1:92,552,363...92,590,377
Ensembl chr 1:92,552,363...92,590,374

G

Fc gamma receptor 1A

increases expression

EXP

furan results in increased expression of FCGR1A mRNA

NCBI chr 2:186,539,941...186,548,941
Ensembl chr 2:186,539,942...186,548,858

G

FCH and mu domain containing endocytic adaptor 2

increases expression

EXP

furan results in increased expression of FCHO2 mRNA

NCBI chr 2:31,813,356...31,916,471
Ensembl chr 2:31,814,950...31,915,445

G

Fc mu receptor

increases expression

EXP

furan results in increased expression of FCMR mRNA

NCBI chr13:44,889,628...44,903,926
Ensembl chr13:44,889,697...44,906,314

G

Fc receptor-like 2

increases expression

EXP

furan results in increased expression of FCRL2 mRNA

PMID:26194646 PMID:27387713

NCBI chr 2:174,992,226...175,005,177
Ensembl chr 2:174,992,226...175,004,967

G

Fc receptor-like A

increases expression

EXP

furan results in increased expression of FCRLA mRNA

NCBI chr13:85,693,177...85,702,875
Ensembl chr13:85,693,122...85,703,176

G

ferredoxin-fold anticodon binding domain containing 1

increases methylation

EXP

furan results in increased methylation of FDXACB1 gene

NCBI chr 8:60,009,818...60,014,625

G

fem-1 homolog A

increases expression

EXP

furan results in increased expression of FEM1A mRNA

NCBI chr 9:1,178,857...1,181,063
Ensembl chr 9:1,177,543...1,188,006

G

flap structure-specific endonuclease 1

increases expression

EXP

furan results in increased expression of FEN1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016

G

FERM domain containing kindlin 1

increases expression

EXP

furan results in increased expression of FERMT1 mRNA

NCBI chr 3:140,624,434...140,666,419
Ensembl chr 3:140,624,434...140,666,419

G

FES proto-oncogene, tyrosine kinase

increases expression

EXP

furan results in increased expression of FES mRNA

NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181

G

fetuin B

decreases expression

EXP

furan results in decreased expression of FETUB mRNA

PMID:15120968 PMID:25539665

NCBI chr11:91,586,750...91,599,789
Ensembl chr11:91,586,748...91,599,310

G

free fatty acid receptor 4

increases expression

EXP

furan results in increased expression of FFAR4 mRNA

NCBI chr 1:245,286,009...245,304,029
Ensembl chr 1:245,285,883...245,304,031

G

fibrinogen alpha chain

increases methylation
decreases expression

EXP

furan results in increased methylation of FGA gene
furan results in decreased expression of FGA mRNA

PMID:15120968 PMID:22079235 PMID:25539665

NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577

G

fibrinogen beta chain

increases methylation
decreases expression

EXP

furan results in increased methylation of FGB gene
furan results in decreased expression of FGB mRNA

PMID:22079235 PMID:26194646

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434

G

FYVE, RhoGEF and PH domain containing 1

decreases expression

EXP

furan results in decreased expression of FGD1 mRNA

NCBI chr X:23,466,791...23,509,773
Ensembl chr X:23,467,530...23,509,979

G

FYVE, RhoGEF and PH domain containing 2

increases expression

EXP

furan results in increased expression of FGD2 mRNA

NCBI chr20:7,426,407...7,443,207
Ensembl chr20:7,426,414...7,443,207

G

FYVE, RhoGEF and PH domain containing 6

decreases methylation
increases expression

EXP

furan results in decreased methylation of FGD6 gene
furan results in increased expression of FGD6 mRNA

NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:30,484,600...30,595,806

G

fibroblast growth factor 1

decreases expression

EXP

furan results in decreased expression of FGF1 mRNA

NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393

G

fibroblast growth factor 11

increases methylation

EXP

furan results in increased methylation of FGF11 gene

NCBI chr10:55,015,232...55,020,773
Ensembl chr10:55,016,411...55,020,454

G

fibroblast growth factor 13

increases expression

EXP

furan results in increased expression of FGF13 mRNA

NCBI chr X:142,312,381...142,838,581
Ensembl chr X:142,312,391...142,423,536

G

fibroblast growth factor 14

decreases expression

EXP

furan results in decreased expression of FGF14 mRNA

NCBI chr15:107,442,800...108,086,486
Ensembl chr15:107,451,634...108,085,808

G

fibroblast growth factor 16

decreases expression

EXP

furan results in decreased expression of FGF16 mRNA

NCBI chr X:74,882,863...74,893,598
Ensembl chr X:74,882,995...74,944,246

G

fibroblast growth factor 19

multiple interactions
increases expression

ISO
EXP

[furan co-treated with rhodioloside] results in increased expression of FGF15 mRNA
furan results in increased expression of FGF19 mRNA

PMID:32251705 PMID:38160780

NCBI chr 1:209,485,813...209,490,267
Ensembl chr 1:209,485,813...209,490,267

G

fibroblast growth factor 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of FGF2 gene
furan results in increased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

fibroblast growth factor 21

increases expression

ISO
EXP

furan results in increased expression of FGF21 mRNA

PMID:24183702 PMID:26194646 PMID:37517673

NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056

G

fibroblast growth factor binding protein 1

increases expression

EXP

furan results in increased expression of FGFBP1 mRNA

NCBI chr14:71,316,171...71,319,965
Ensembl chr14:71,317,065...71,320,309

G

Fibroblast growth factor receptor 1

increases expression

EXP

furan results in increased expression of FGFR1 mRNA

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

fibrinogen gamma chain

affects binding
decreases expression

EXP

furan binds to FGG protein
furan results in decreased expression of FGG mRNA

PMID:22240984 PMID:25539665

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

FGGY carbohydrate kinase domain containing

decreases expression

EXP

furan results in decreased expression of FGGY mRNA

NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714

G

fibrinogen-like 1

increases methylation
decreases expression

EXP

furan results in increased methylation of FGL1 gene
furan results in decreased expression of FGL1 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429

G

forkhead associated phosphopeptide binding domain 1

increases methylation

EXP

furan results in increased methylation of FHAD1 gene

NCBI chr 5:159,474,111...159,593,455
Ensembl chr 5:159,474,158...159,593,367

G

four and a half LIM domains 1

increases expression

EXP

furan results in increased expression of FHL1 mRNA

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282

G

four and a half LIM domains 2

increases expression

EXP

furan results in increased expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326

G

four and a half LIM domains 4

increases expression

EXP

furan results in increased expression of FHL4 mRNA

NCBI chr 7:20,516,308...20,521,111
Ensembl chr 7:20,483,954...20,527,283

G

fin bud initiation factor homolog

decreases expression
increases expression

ISO
EXP

furan results in decreased expression of FIBIN mRNA
furan results in increased expression of FIBIN mRNA

PMID:24183702 PMID:27387713

NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479

G

fidgetin-like 1

increases expression

EXP

furan results in increased expression of FIGNL1 mRNA

NCBI chr14:90,573,090...90,595,342
Ensembl chr14:90,581,771...90,592,316

G

filamin A interacting protein 1

increases expression

EXP

furan results in increased expression of FILIP1 mRNA

NCBI chr 8:89,641,509...89,836,772
Ensembl chr 8:89,644,579...89,802,771

G

FKBP prolyl isomerase 10

increases expression

EXP

furan results in increased expression of FKBP10 mRNA

NCBI chr10:85,845,801...85,858,361
Ensembl chr10:85,844,703...85,858,355

G

FKBP prolyl isomerase 11

increases expression

EXP

furan results in increased expression of FKBP11 mRNA

NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123

G

FKBP prolyl isomerase 14

increases expression

EXP

furan results in increased expression of FKBP14 mRNA

NCBI chr 4:85,035,840...85,051,917
Ensembl chr 4:85,037,145...85,051,808

G

FKBP prolyl isomerase 2

decreases expression

EXP

furan results in decreased expression of FKBP2 mRNA

NCBI chr 1:213,596,931...213,599,606
Ensembl chr 1:213,596,931...213,600,790

G

FKBP prolyl isomerase 5

increases expression

EXP

furan results in increased expression of FKBP5 mRNA

NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118

G

FKBP prolyl isomerase 7

increases expression

EXP

furan results in increased expression of FKBP7 mRNA

NCBI chr 3:82,016,647...82,030,913
Ensembl chr 3:82,016,513...82,028,573

G

filamin B

increases methylation

EXP

furan results in increased methylation of FLNB gene

NCBI chr15:19,392,212...19,525,278
Ensembl chr15:19,392,216...19,525,209

G

filamin C

increases expression

EXP

furan results in increased expression of FLNC mRNA

NCBI chr 4:58,999,445...59,027,240
Ensembl chr 4:58,999,547...59,027,240

G

flotillin 2

increases methylation

EXP

furan results in increased methylation of FLOT2 gene

NCBI chr10:63,424,084...63,445,811
Ensembl chr10:63,423,806...63,445,810

G

fibronectin leucine rich transmembrane protein 1

decreases expression

EXP

furan results in decreased expression of FLRT1 mRNA

NCBI chr 1:213,704,983...213,782,958
Ensembl chr 1:213,704,038...213,782,981

G

fibronectin leucine rich transmembrane protein 2

increases expression
decreases methylation

EXP

furan results in increased expression of FLRT2 mRNA
furan results in decreased methylation of FLRT2 gene

NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004

G

fibronectin leucine rich transmembrane protein 3

increases expression

EXP

furan results in increased expression of FLRT3 mRNA

NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650

G

Fms related receptor tyrosine kinase 3

increases expression

EXP

furan results in increased expression of FLT3 mRNA

NCBI chr12:12,660,035...12,735,584
Ensembl chr12:12,659,946...12,735,581

G

FLVCR choline and putative heme transporter 2

increases expression

EXP

furan results in increased expression of FLVCR2 mRNA

NCBI chr 6:111,139,352...111,203,345
Ensembl chr 6:111,139,295...111,203,345

G

flavin containing dimethylaniline monoxygenase 2

increases expression

EXP

furan results in increased expression of FMO2 mRNA

PMID:26194646 PMID:27387713

NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534

G

flavin containing dimethylaniline monoxygenase 3

increases methylation

EXP

furan results in increased methylation of FMO3 gene

NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256

G

fibromodulin

increases expression

EXP

furan results in increased expression of FMOD mRNA

NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183

G

fragile X messenger ribonucleoprotein 1

decreases expression

EXP

furan results in decreased expression of FMR1 mRNA

NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675

G

fibronectin 1

increases methylation

EXP

furan results in increased methylation of FN1 gene

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

fructosamine 3 kinase

increases expression

EXP

furan results in increased expression of FN3K mRNA

NCBI chr10:107,198,566...107,214,176
Ensembl chr10:107,198,892...107,214,175

G

formin binding protein 1-like

increases methylation

EXP

furan results in increased methylation of FNBP1L gene

NCBI chr 2:213,331,871...213,432,821
Ensembl chr 2:213,318,662...213,423,051

G

fibronectin type III domain containing 1

increases expression

EXP

furan results in increased expression of FNDC1 mRNA

NCBI chr 1:49,686,856...49,769,263
Ensembl chr 1:49,686,856...49,769,263

G

fibronectin type III domain containing 3B

increases expression

ISO

furan results in increased expression of FNDC3B mRNA

NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306

G

fibronectin type III domain containing 5

decreases expression

EXP

furan results in decreased expression of FNDC5 mRNA

NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:146,751,416...146,778,540

G

fibronectin type III domain containing 8

decreases expression

EXP

furan results in decreased expression of FNDC8 mRNA

NCBI chr10:68,323,500...68,331,638
Ensembl chr10:68,323,497...68,331,639

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

EXP

furan results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

forkhead box A3

increases methylation

EXP

furan results in increased methylation of FOXA3 gene

NCBI chr 1:87,790,111...87,800,259
Ensembl chr 1:87,790,012...87,800,953

G

forkhead box C1

increases expression

EXP

furan results in increased expression of FOXC1 mRNA

NCBI chr17:32,840,119...32,844,100
Ensembl chr17:32,805,858...32,844,347

G

forkhead box E1

decreases expression
increases methylation

EXP

furan results in decreased expression of FOXE1 mRNA
furan results in increased methylation of FOXE1 gene

PMID:25539665 PMID:27387713

NCBI chr 5:65,425,630...65,428,438
Ensembl chr 5:65,425,630...65,428,438

G

forkhead box N1

increases methylation

EXP

furan results in increased methylation of FOXN1 gene

NCBI chr10:63,749,461...63,778,468
Ensembl chr10:63,749,461...63,771,771

G

forkhead box N4

increases expression

EXP

furan results in increased expression of FOXN4 mRNA

NCBI chr12:47,997,308...48,020,526
Ensembl chr12:48,000,257...48,020,526

G

forkhead box O3

increases expression

EXP

furan results in increased expression of FOXO3 mRNA

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

forkhead box S1

increases expression

EXP

furan results in increased expression of FOXS1 mRNA

NCBI chr 3:161,857,264...161,858,548
Ensembl chr 3:161,850,782...161,858,662

G

formyl peptide receptor 2 like 1

increases expression

EXP

furan results in increased expression of FPR-RS3 mRNA

NCBI chr 1:68,359,518...68,360,549
Ensembl chr 1:68,359,518...68,360,549

G

FERM and PDZ domain containing 1

increases expression

EXP

furan results in increased expression of FRMPD1 mRNA

NCBI chr 5:64,238,730...64,340,778
Ensembl chr 5:64,238,768...64,340,776

G

FRY microtubule binding protein

increases expression

EXP

furan results in increased expression of FRY mRNA

NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603

G

frizzled-related protein

increases expression

EXP

furan results in increased expression of FRZB mRNA

NCBI chr 3:85,739,162...85,772,168
Ensembl chr 3:85,739,165...85,772,096

G

follicle stimulating hormone subunit beta

multiple interactions
decreases expression

EXP

protocatechuic acid inhibits the reaction [furan results in decreased expression of FSHB protein]

NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072

G

fibrous sheath interacting protein 1

increases expression

EXP

furan results in increased expression of FSIP1 mRNA

NCBI chr 3:125,528,538...125,671,135
Ensembl chr 3:125,524,528...125,671,135

G

follistatin

increases expression

ISO
EXP

furan results in increased expression of FST mRNA

PMID:24183702 PMID:27387713

NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491

G

follistatin-like 1

increases expression
decreases methylation

EXP

furan results in increased expression of FSTL1 mRNA
furan results in decreased methylation of FSTL1 gene

NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126

G

formimidoyltransferase cyclodeaminase

affects binding

EXP

furan binds to FTCD protein

NCBI chr20:12,054,710...12,068,219
Ensembl chr20:12,054,711...12,068,237

G

ferritin light chain 1 like 6

increases expression

EXP

furan results in increased expression of FTL1L6 mRNA

NCBI chr 2:53,124,485...53,126,902

G

FUN14 domain containing 2

increases methylation

EXP

furan results in increased methylation of FUNDC2 gene

NCBI chr18:142,829...155,123
Ensembl chr18:142,640...155,674

G

fucosyltransferase 2

increases expression

EXP

furan results in increased expression of FUT2 mRNA

NCBI chr 1:105,256,013...105,276,828
Ensembl chr 1:105,255,390...105,276,647

G

fucosyltransferase 4

increases expression

EXP

furan results in increased expression of FUT4 mRNA

NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:19,868,079...19,872,436

G

FMR1 autosomal homolog 1

increases methylation

EXP

furan results in increased methylation of FXR1 gene

NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027

G

FXYD domain-containing ion transport regulator 1

decreases expression

EXP

furan results in decreased expression of FXYD1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:95,414,556...95,418,645
Ensembl chr 1:95,414,557...95,418,591

G

FXYD domain-containing ion transport regulator 2

increases expression

EXP

furan results in increased expression of FXYD2 mRNA

NCBI chr 8:54,609,658...54,616,788
Ensembl chr 8:54,609,658...54,616,957

G

FXYD domain-containing ion transport regulator 3

increases expression

EXP

furan results in increased expression of FXYD3 mRNA

NCBI chr 1:95,432,918...95,440,129
Ensembl chr 1:95,432,919...95,439,702

G

FXYD domain-containing ion transport regulator 6

increases expression

EXP

furan results in increased expression of FXYD6 mRNA

NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715

G

frizzled class receptor 1

decreases expression

EXP

furan results in decreased expression of FZD1 mRNA

NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176

G

frizzled class receptor 2

increases expression
decreases methylation

EXP

furan results in increased expression of FZD2 mRNA
furan results in decreased methylation of FZD2 gene

NCBI chr10:88,061,988...88,063,898
Ensembl chr10:88,061,667...88,065,396

G

frizzled class receptor 3

increases expression
decreases expression

EXP

furan results in increased expression of FZD3 mRNA
furan results in decreased expression of FZD3 mRNA

NCBI chr15:43,596,962...43,664,047
Ensembl chr15:43,596,965...43,663,960

G

frizzled class receptor 6

increases expression

EXP

furan results in increased expression of FZD6 mRNA

PMID:25539665 PMID:27387713

NCBI chr 7:71,939,916...71,971,685
Ensembl chr 7:71,939,973...71,971,680

G

frizzled class receptor 8

decreases expression

ISO

furan results in decreased expression of FZD8 mRNA

NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961

G

G0/G1switch 2

decreases expression

EXP

furan results in decreased expression of G0S2 mRNA

NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293

G

glucose-6-phosphatase catalytic subunit 1

decreases expression

EXP

furan results in decreased expression of G6PC1 mRNA

NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033

G

glucose 6 phosphatase catalytic subunit 3

increases expression

EXP

furan results in increased expression of G6PC3 mRNA

NCBI chr10:87,647,149...87,651,385
Ensembl chr10:87,647,062...87,653,453

G

glucose-6-phosphate dehydrogenase

increases expression
decreases activity
multiple interactions

EXP

furan results in increased expression of G6PD mRNA
furan results in decreased activity of G6PD protein
protocatechuic acid inhibits the reaction [furan results in decreased activity of G6PD protein]

PMID:25539665 PMID:26194646 PMID:32758512

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

gamma-aminobutyric acid type A receptor subunit epsilon

increases methylation

EXP

furan results in increased methylation of GABRE gene

NCBI chr X:155,102,078...155,120,821
Ensembl chr X:155,102,083...155,120,735

G

gamma-aminobutyric acid type A receptor subunit pi

increases methylation

EXP

furan results in increased methylation of GABRP gene

NCBI chr10:18,647,243...18,673,806
Ensembl chr10:18,647,243...18,673,727

G

glutamate decarboxylase 1

increases methylation

EXP

furan results in increased methylation of GAD1 gene

NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759

G

growth arrest and DNA-damage-inducible, alpha

increases expression

EXP

furan results in increased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

EXP

furan results in decreased expression of GADD45G mRNA

NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369

G

galanin and GMAP prepropeptide

increases methylation

EXP

furan results in increased methylation of GAL gene

NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229

G

galactose-3-O-sulfotransferase 1

increases expression

EXP

furan results in increased expression of GAL3ST1 mRNA

PMID:25539665 PMID:27387713

NCBI chr14:83,094,265...83,109,992
Ensembl chr14:83,094,385...83,109,978

G

polypeptide N-acetylgalactosaminyltransferase 12

increases expression

EXP

furan results in increased expression of GALNT12 mRNA

NCBI chr 5:66,180,171...66,208,931
Ensembl chr 5:66,180,164...66,208,938

G

polypeptide N-acetylgalactosaminyltransferase 16

increases expression

EXP

furan results in increased expression of GALNT16 mRNA

NCBI chr 6:105,900,987...105,982,039
Ensembl chr 6:105,901,153...105,991,350

G

polypeptide N-acetylgalactosaminyltransferase 2

increases methylation

EXP

furan results in increased methylation of GALNT2 gene

NCBI chr19:69,110,657...69,222,237
Ensembl chr19:69,110,657...69,222,237

G

polypeptide N-acetylgalactosaminyltransferase 3

increases expression

EXP

furan results in increased expression of GALNT3 mRNA

NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323

G

polypeptide N-acetylgalactosaminyltransferase 5

decreases methylation

EXP

furan results in decreased methylation of GALNT5 gene

NCBI chr 3:62,982,465...63,028,724
Ensembl chr 3:62,982,465...63,028,724

G

galanin receptor 2

increases expression

EXP

furan results in increased expression of GALR2 mRNA

NCBI chr10:102,012,086...102,016,057
Ensembl chr10:102,013,370...102,016,055

G

galactose-1-phosphate uridylyltransferase

increases methylation
increases expression

EXP

furan results in increased methylation of GALT gene
furan results in increased expression of GALT mRNA

PMID:22079235 PMID:26194646

NCBI chr 5:61,722,871...61,726,128
Ensembl chr 5:61,722,466...61,726,125

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression
affects activity
affects binding

EXP

furan results in increased expression of GAPDH mRNA
furan affects the activity of GAPDH protein
furan binds to GAPDH protein

PMID:15120968 PMID:22240984 PMID:27402187

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377

G

golgi associated RAB2 interactor family member 3

increases expression

EXP

furan results in increased expression of GARIN3 mRNA

NCBI chr10:31,331,196...31,334,434
Ensembl chr10:31,331,177...31,334,430

G

golgi associated RAB2 interactor family member 4

decreases expression

EXP

furan results in decreased expression of GARIN4 mRNA

NCBI chr13:105,274,107...105,276,287
Ensembl chr13:105,274,106...105,276,286

G

growth arrest specific 5

increases expression

EXP

furan results in increased expression of GAS5 mRNA

NCBI chr13:75,836,963...75,840,284

G

growth arrest specific 6

increases expression
decreases expression

ISO
EXP

furan results in increased expression of GAS6 mRNA
furan results in decreased expression of GAS6 mRNA

PMID:24183702 PMID:25539665

NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088

G

growth arrest specific 8

increases expression

EXP

furan results in increased expression of GAS8 mRNA

NCBI chr19:68,461,280...68,480,810
Ensembl chr19:68,461,304...68,480,806

G

golgi associated kinase 1A

decreases expression

EXP

furan results in decreased expression of GASK1A mRNA

NCBI chr 8:130,488,279...130,521,242
Ensembl chr 8:130,488,354...130,521,242

G

golgi associated kinase 1B

increases expression

EXP

furan results in increased expression of GASK1B mRNA

NCBI chr 2:167,345,738...167,410,606
Ensembl chr 2:167,345,809...167,410,603

G

GATA binding protein 2

increases expression

EXP

furan results in increased expression of GATA2 mRNA

NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:122,211,829...122,225,055

G

GC, vitamin D binding protein

affects binding
increases methylation

EXP

furan binds to GC protein
furan results in increased methylation of GC gene

PMID:22079235 PMID:22240984

NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673

G

grancalcin

increases expression

EXP

furan results in increased expression of GCA mRNA

NCBI chr 3:67,705,874...67,738,475
Ensembl chr 3:67,705,890...67,737,387

G

GTP cyclohydrolase 1

increases methylation

EXP

furan results in increased methylation of GCH1 gene

NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412

G

glucokinase

increases methylation
decreases expression

EXP

furan results in increased methylation of GCK gene
furan results in decreased expression of GCK mRNA

PMID:22079235 PMID:25539665

NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949

G

glucokinase regulator

decreases expression

EXP

furan results in decreased expression of GCKR mRNA

NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
increases expression

ISO
EXP

[Bromodeoxyuridine co-treated with furan] results in increased expression of GCLC mRNA
furan results in increased expression of GCLC mRNA

PMID:24183702 PMID:24910943 PMID:27402187

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glucosaminyl (N-acetyl) transferase 1

increases expression

EXP

furan results in increased expression of GCNT1 mRNA

NCBI chr 1:224,145,104...224,182,496
Ensembl chr 1:224,141,108...224,185,741

G

glucosaminyl (N-acetyl) transferase 2

increases expression

ISO

furan results in increased expression of GCNT2 mRNA

NCBI chr17:24,002,592...24,107,339
Ensembl chr17:24,002,597...24,106,989

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

EXP

furan results in increased expression of GCNT3 mRNA

PMID:26194646 PMID:27387713

NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:79,566,753...79,581,595

G

ganglioside-induced differentiation-associated-protein 2

increases methylation

EXP

furan results in increased methylation of GDAP2 gene

NCBI chr 2:190,217,158...190,276,128
Ensembl chr 2:190,217,164...190,276,126

G

growth differentiation factor 11

increases expression

EXP

furan results in increased expression of GDF11 mRNA

NCBI chr 7:1,896,229...1,909,147
Ensembl chr 7:1,896,229...1,905,222

G

growth differentiation factor 15

increases methylation
decreases expression
increases expression
multiple interactions

EXP
ISO

furan results in increased methylation of GDF15 gene
furan results in decreased expression of GDF15 mRNA
furan results in increased expression of GDF15 mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA

PMID:22079235 PMID:24183702 PMID:24910943 PMID:26194646 PMID:37517673

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022

G

growth differentiation factor 6

increases methylation

EXP

furan results in increased methylation of GDF6 gene

NCBI chr 5:27,793,561...27,809,884
Ensembl chr 5:27,793,552...27,811,825

G

growth differentiation factor 9

increases expression

ISO

furan results in increased expression of GDF9 mRNA

PMID:24183702 PMID:37517673

NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797

G

glial cell derived neurotrophic factor

decreases expression

EXP

furan results in decreased expression of GDNF mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240

G

glycerophosphodiester phosphodiesterase domain containing 5

increases methylation

EXP

furan results in increased methylation of GDPD5 gene

NCBI chr 1:163,091,844...163,173,559
Ensembl chr 1:163,091,833...163,173,559

G

glial fibrillary acidic protein

decreases expression
increases expression

EXP

furan results in decreased expression of GFAP mRNA
furan results in increased expression of GFAP mRNA

NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685

G

GTP dependent ribosome recycling factor mitochondrial 2

increases expression

EXP

furan results in increased expression of GFM2 mRNA

NCBI chr 2:30,184,063...30,222,811
Ensembl chr 2:30,184,115...30,222,806

G

glutamine-fructose-6-phosphate transaminase 2

decreases expression

EXP

furan results in decreased expression of GFPT2 mRNA

NCBI chr10:34,616,146...34,662,420
Ensembl chr10:34,615,370...34,662,419

G

GDNF family receptor alpha 1

decreases expression

EXP

furan results in decreased expression of GFRA1 mRNA

NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501

G

GDNF family receptor alpha 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of GFRA2 gene
furan results in increased expression of GFRA2 mRNA

NCBI chr15:52,351,499...52,443,369
Ensembl chr15:52,351,514...52,477,782

G

GDNF family receptor alpha 3

increases expression

EXP

furan results in increased expression of GFRA3 mRNA

NCBI chr18:26,571,952...26,600,225
Ensembl chr18:26,571,921...26,600,225

G

gamma-glutamyl cyclotransferase

decreases expression

EXP

furan results in decreased expression of GGCT mRNA

NCBI chr 4:85,453,387...85,459,597
Ensembl chr 4:85,453,387...85,470,224

G

gametogenetin binding protein 1

increases expression

EXP

furan results in increased expression of GGNBP1 mRNA

NCBI chr20:5,111,734...5,118,034
Ensembl chr20:5,101,165...5,118,030

G

gamma-glutamyltransferase 1

increases expression

EXP

furan results in increased expression of GGT1 mRNA

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050

G

growth hormone receptor

decreases expression

EXP

furan results in decreased expression of GHR mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331

G

ghrelin and obestatin prepropeptide

increases expression

EXP

furan results in increased expression of GHRL mRNA

NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:148,421,315...148,425,969

G

GTPase, IMAP family member 4

increases expression

EXP

furan results in increased expression of GIMAP4 mRNA

NCBI chr 4:78,967,297...78,974,211
Ensembl chr 4:78,967,297...78,974,202

G

GIMAP family P-loop NTPase domain containing 1

decreases expression

EXP

furan results in decreased expression of GIMD1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:223,777,876...223,812,582
Ensembl chr 2:223,777,889...223,812,576

G

GINS complex subunit 1

increases expression

EXP

furan results in increased expression of GINS1 mRNA

NCBI chr 3:160,184,920...160,206,334
Ensembl chr 3:160,180,151...160,206,332

G

GINS complex subunit 2

increases methylation
increases expression

EXP

furan results in increased methylation of GINS2 gene
furan results in increased expression of GINS2 mRNA

PMID:22079235 PMID:25539665

NCBI chr19:65,535,492...65,548,270
Ensembl chr19:65,535,492...65,548,052

G

GINS complex subunit 3

increases methylation

EXP

furan results in increased methylation of GINS3 gene

NCBI chr19:9,426,140...9,435,192
Ensembl chr19:9,399,759...9,434,679

G

GINS complex subunit 4

increases expression

EXP

furan results in increased expression of GINS4 mRNA

NCBI chr16:75,489,990...75,502,455
Ensembl chr16:75,490,126...75,505,000

G

gastric inhibitory polypeptide

increases expression

EXP

furan results in increased expression of GIP mRNA

NCBI chr10:81,465,070...81,473,216
Ensembl chr10:81,465,062...81,473,216

G

GIPC PDZ domain containing family, member 2

increases expression

EXP

furan results in increased expression of GIPC2 mRNA

PMID:25539665 PMID:27387713

NCBI chr 2:243,690,742...243,770,199
Ensembl chr 2:243,690,748...243,770,199

G

GIPC PDZ domain containing family, member 3

increases methylation

EXP

furan results in increased methylation of GIPC3 gene

NCBI chr 7:9,026,905...9,034,005
Ensembl chr 7:9,026,905...9,034,795

G

gastric inhibitory polypeptide receptor

decreases expression

EXP

furan results in decreased expression of GIPR mRNA

NCBI chr 1:87,932,316...87,956,084
Ensembl chr 1:87,932,623...87,942,492

G

GIT ArfGAP 2

increases methylation

EXP

furan results in increased methylation of GIT2 gene

NCBI chr12:47,490,350...47,531,232
Ensembl chr12:47,490,369...47,533,250

G

gap junction protein, alpha 1

increases methylation
increases expression

EXP

furan results in increased methylation of GJA1 gene
furan results in increased expression of GJA1 mRNA

PMID:22079235 PMID:27387713

NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689

G

gap junction protein, alpha 3

increases methylation

EXP

furan results in increased methylation of GJA3 gene

NCBI chr15:35,296,946...35,322,405
Ensembl chr15:35,295,523...35,322,809

G

gap junction protein, alpha 5

increases expression

EXP

furan results in increased expression of GJA5 mRNA

NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512

G

gap junction protein, beta 3

increases expression

EXP

furan results in increased expression of GJB3 mRNA

NCBI chr 5:144,933,692...144,939,435
Ensembl chr 5:144,933,696...144,940,280

G

gap junction protein, beta 4

increases expression

EXP

furan results in increased expression of GJB4 mRNA

NCBI chr 5:144,948,231...144,964,014
Ensembl chr 5:144,951,184...144,964,097

G

gap junction protein, gamma 1

increases expression

EXP

furan results in increased expression of GJA7 mRNA

NCBI chr10:88,262,840...88,285,646
Ensembl chr10:88,249,489...88,285,853

G

gap junction protein, epsilon 1

decreases expression

EXP

furan results in decreased expression of GJE1 mRNA

NCBI chr 1:10,905,890...10,911,800
Ensembl chr 1:10,905,890...10,908,305

G

galactosidase, alpha

increases methylation

EXP

furan results in increased methylation of GLA gene

NCBI chr X:102,062,497...102,073,915
Ensembl chr X:102,056,718...102,073,915

G

galactosidase, beta 1-like

decreases methylation
increases expression

EXP

furan results in decreased methylation of GLB1L gene
furan results in increased expression of GLB1L mRNA

NCBI chr 9:84,141,993...84,154,176
Ensembl chr 9:84,143,841...84,154,176

G

GLI family zinc finger 2

increases expression

EXP

furan results in increased expression of GLI2 mRNA

NCBI chr13:32,499,678...32,716,418
Ensembl chr13:32,499,678...32,716,418

G

GLIS family zinc finger 2

increases expression

EXP

furan results in increased expression of GLIS2 mRNA

NCBI chr10:11,457,594...11,484,948
Ensembl chr10:11,457,792...11,477,995

G

glyoxalase domain containing 5

decreases expression
increases expression

EXP

furan results in decreased expression of GLOD5 mRNA
furan results in increased expression of GLOD5 mRNA

PMID:26194646 PMID:27387713

NCBI chr X:17,145,936...17,160,733
Ensembl chr X:17,145,938...17,160,619

G

glycine receptor, beta

increases methylation

EXP

furan results in increased methylation of GLRB gene

NCBI chr 2:168,432,736...168,505,614
Ensembl chr 2:168,432,736...168,505,614

G

glutaminase

increases expression
decreases methylation

EXP

furan results in increased expression of GLS mRNA
furan results in decreased methylation of GLS gene

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861

G

glycolipid transfer protein

increases methylation

EXP

furan results in increased methylation of GLTP gene

NCBI chr12:47,567,797...47,587,949
Ensembl chr12:47,567,770...47,587,946

G

glycolipid transfer protein domain containing 2

decreases expression

EXP

furan results in decreased expression of GLTPD2 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:55,732,199...55,734,974
Ensembl chr10:55,732,208...55,734,735

G

germ cell-less 1, spermatogenesis associated

decreases expression

EXP

furan results in decreased expression of GMCL1 mRNA

NCBI chr 4:120,697,976...120,737,267
Ensembl chr 4:120,697,976...120,737,257

G

GDP-mannose 4, 6-dehydratase

increases expression

EXP

furan results in increased expression of GMDS mRNA

NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,304,056...32,830,706

G

glia maturation factor, beta

increases expression

EXP

furan results in increased expression of GMFB mRNA

NCBI chr15:22,549,705...22,560,125
Ensembl chr15:22,547,034...22,560,308

G

geminin, DNA replication inhibitor

increases expression

EXP

furan results in increased expression of GMNN mRNA

NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,729,824...40,738,068

G

guanosine monophosphate reductase

increases expression

EXP

furan results in increased expression of GMPR mRNA

NCBI chr17:19,357,992...19,395,807
Ensembl chr17:19,357,992...19,431,655

G

G protein subunit alpha 14

increases expression

EXP

furan results in increased expression of GNA14 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 1:223,141,802...223,324,210
Ensembl chr 1:223,141,802...223,324,210

G

G protein subunit alpha 15

increases expression

EXP

furan results in increased expression of GNA15 mRNA

NCBI chr 7:8,835,396...8,856,269
Ensembl chr 7:8,835,357...8,856,268

G

G protein subunit alpha i1

increases expression

EXP

furan results in increased expression of GNAI1 mRNA

NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198

G

G protein subunit alpha transducin 1

increases expression

ISO
EXP

furan results in increased expression of GNAT1 mRNA

PMID:24183702 PMID:25539665

NCBI chr 8:117,229,575...117,234,311
Ensembl chr 8:117,229,575...117,234,311

G

G protein subunit gamma 11

increases expression

EXP

furan results in increased expression of GNG11 mRNA

NCBI chr 4:32,977,681...32,983,121
Ensembl chr 4:32,977,664...32,984,438

G

G protein subunit gamma 13

increases expression

EXP

furan results in increased expression of GNG13 mRNA

NCBI chr10:15,245,698...15,247,602
Ensembl chr10:15,245,698...15,247,602

G

G protein subunit gamma 7

increases methylation

EXP

furan results in increased methylation of GNG7 gene

NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923

G

G protein subunit gamma 8

increases expression

EXP

furan results in increased expression of GNG8 mRNA

NCBI chr 1:86,692,609...86,696,463
Ensembl chr 1:86,692,642...86,696,408

G

glycine N-methyltransferase

decreases expression

EXP

furan results in decreased expression of GNMT mRNA

NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692

G

golgi membrane protein 1

increases expression

ISO

furan results in increased expression of GOLM1 mRNA

NCBI chr17:4,996,978...5,049,278
Ensembl chr17:4,996,223...5,047,414

G

golgi membrane protein 2

increases expression

EXP

furan results in increased expression of GOLM2 mRNA

NCBI chr 3:129,280,623...129,349,895
Ensembl chr 3:129,280,701...129,349,895

G

golgi phosphoprotein 3

increases methylation

EXP

furan results in increased methylation of GOLPH3 gene

NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:63,074,256...63,113,577

G

golgi phosphoprotein 3-like

increases methylation

EXP

furan results in increased methylation of GOLPH3L gene

NCBI chr 2:185,840,879...185,872,037
Ensembl chr 2:185,840,958...185,872,043

G

golgin, RAB6-interacting

increases expression

EXP

furan results in increased expression of GORAB mRNA

PMID:25539665 PMID:27387713

NCBI chr13:78,278,868...78,295,490
Ensembl chr13:78,278,871...78,295,488

G

glutamic-oxaloacetic transaminase 1-like 1

increases expression

EXP

furan results in increased expression of GOT1L1 mRNA

NCBI chr16:71,563,562...71,576,446
Ensembl chr16:71,563,534...71,570,468

G

glycoprotein Ib platelet subunit beta

decreases expression

EXP

furan results in decreased expression of GP1BB mRNA

PMID:25539665 PMID:26194646

NCBI chr11:95,882,561...95,883,738

G

glycoprotein A33

increases expression

EXP

furan results in increased expression of GPA33 mRNA

NCBI chr13:80,914,119...80,947,738
Ensembl chr13:80,912,430...80,948,903

G

glycerol-3-phosphate acyltransferase 3

increases expression

EXP

furan results in increased expression of GPAT3 mRNA

NCBI chr14:9,018,762...9,072,552

G

glycerol-3-phosphate acyltransferase 4

decreases expression

EXP

furan results in decreased expression of GPAT4 mRNA

NCBI chr16:75,515,935...75,555,431
Ensembl chr16:75,521,640...75,557,847

G

G patch domain containing 11

increases methylation
increases expression

EXP

furan results in increased methylation of GPATCH11 gene
furan results in increased expression of GPATCH11 mRNA

PMID:22079235 PMID:25539665

NCBI chr 6:21,982,074...21,995,562
Ensembl chr 6:21,985,202...21,995,381

G

G protein-coupled bile acid receptor 1

increases expression

EXP

furan results in increased expression of GPBAR1 mRNA

NCBI chr 9:83,309,895...83,312,397
Ensembl chr 9:83,311,246...83,315,608

G

GC-rich promoter binding protein 1-like 1

increases methylation

EXP

furan results in increased methylation of GPBP1L1 gene

NCBI chr 5:135,245,188...135,287,299
Ensembl chr 5:135,247,342...135,287,298

G

glypican 3

increases expression

EXP

furan results in increased expression of GPC3 mRNA

NCBI chr X:136,789,770...137,157,598
Ensembl chr X:136,789,770...137,157,639

G

glycerophosphocholine phosphodiesterase 1

decreases expression

ISO

furan results in decreased expression of GPCPD1 mRNA

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:140,240,575...140,285,372

G

glycerol-3-phosphate dehydrogenase 1

affects binding
increases methylation

EXP

furan binds to GPD1 protein
furan results in increased methylation of GPD1 gene

PMID:22079235 PMID:22240984

NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368

G

glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1

increases expression

EXP

furan results in increased expression of GPIHBP1 mRNA

NCBI chr 7:109,166,334...109,169,448
Ensembl chr 7:109,163,160...109,169,448

G

glycosylphosphatidylinositol specific phospholipase D1

increases methylation
decreases expression

EXP

furan results in increased methylation of GPLD1 gene
furan results in decreased expression of GPLD1 mRNA

PMID:22079235 PMID:25539665

NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975

G

glycoprotein m6b

increases expression

EXP

furan results in increased expression of GPM6B mRNA

NCBI chr X:31,689,485...31,836,199
Ensembl chr X:31,690,359...31,733,272

G

glycoprotein nmb

increases expression

EXP

furan results in increased expression of GPNMB mRNA

NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240

G

G protein-coupled receptor 132

increases expression

EXP

furan results in increased expression of GPR132 mRNA

NCBI chr 6:137,745,142...137,763,037
Ensembl chr 6:137,745,241...137,763,157

G

G protein-coupled receptor 137B

increases expression

EXP

furan results in increased expression of GPR137B mRNA

PMID:25539665 PMID:26194646

NCBI chr17:92,987,792...93,026,003
Ensembl chr17:92,942,559...93,025,911

G

G protein-coupled receptor 153

increases expression

EXP

furan results in increased expression of GPR153 mRNA

NCBI chr 5:168,064,134...168,075,697
Ensembl chr 5:168,064,311...168,074,532

G

G protein-coupled receptor 17

increases methylation

EXP

furan results in increased methylation of GPR17 gene

NCBI chr18:23,850,460...23,857,381
Ensembl chr18:23,850,107...23,857,702

G

G protein-coupled receptor 176

decreases methylation
increases expression

EXP

furan results in decreased methylation of GPR176 gene
furan results in increased expression of GPR176 mRNA

NCBI chr 3:125,690,750...125,791,172
Ensembl chr 3:125,690,751...125,791,172

G

G protein-coupled receptor 183

increases expression

EXP

furan results in increased expression of GPR183 mRNA

NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977

G

G protein-coupled receptor 19

increases methylation

EXP

furan results in increased methylation of GPR19 gene

NCBI chr 4:169,442,278...169,468,805
Ensembl chr 4:169,436,658...169,471,249

G

G protein-coupled receptor 3

decreases expression

EXP

furan results in decreased expression of GPR3 mRNA

NCBI chr 5:150,695,406...150,698,526
Ensembl chr 5:150,695,251...150,706,529

G

G protein-coupled receptor 34

increases expression

EXP

furan results in increased expression of GPR34 mRNA

NCBI chr X:11,777,667...11,786,640
Ensembl chr X:11,776,371...11,843,240

G

G protein-coupled receptor 37-like 1

increases expression

EXP

furan results in increased expression of GPR37L1 mRNA

NCBI chr13:49,150,355...49,157,204
Ensembl chr13:49,150,359...49,157,204

G

G protein-coupled receptor 39

increases methylation

EXP

furan results in increased methylation of GPR39 gene

NCBI chr13:39,667,908...39,879,944
Ensembl chr13:39,667,909...39,880,902

G

G protein-coupled receptor 84

increases expression

EXP

furan results in increased expression of GPR84 mRNA

PMID:26194646 PMID:27387713

NCBI chr 7:136,322,374...136,324,648
Ensembl chr 7:136,322,191...136,324,703

G

G protein-coupled receptor, class C, group 5, member A

increases expression

EXP

furan results in increased expression of GPRC5A mRNA

NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:169,634,748...169,653,625

G

G protein-coupled receptor, class C, group 5, member B

increases expression

EXP

furan results in increased expression of GPRC5B mRNA

NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757

G

G protein-coupled receptor, class C, group 5, member C

decreases expression

EXP

furan results in decreased expression of GPRC5C mRNA

NCBI chr10:100,385,682...100,407,953
Ensembl chr10:100,383,631...100,426,962

G

glutamic--pyruvic transaminase

affects expression
decreases expression

EXP

furan affects the expression of GPT protein
furan results in decreased expression of GPT mRNA

PMID:24632374 PMID:27387713

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

glutathione peroxidase 2

increases expression

EXP

furan results in increased expression of GPX2 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862

G

glutathione peroxidase 3

increases expression

EXP

furan results in increased expression of GPX3 mRNA

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405

G

glutathione peroxidase 7

increases expression
decreases methylation

EXP

furan results in increased expression of GPX7 mRNA
furan results in decreased methylation of GPX7 gene

PMID:25539665 PMID:27387713

NCBI chr 5:128,373,881...128,381,866
Ensembl chr 5:128,372,875...128,381,725

G

glutathione peroxidase 8

increases expression

EXP

furan results in increased expression of GPX8 mRNA

NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:46,409,139...46,413,406

G

GRB2-related adaptor protein 2

decreases methylation

EXP

furan results in decreased methylation of GRAP2 gene; furan results in decreased methylation of GRAP2 promoter

NCBI chr 7:113,997,356...114,071,073
Ensembl chr 7:113,997,307...114,075,367

G

growth factor receptor bound protein 14

increases methylation

EXP

furan results in increased methylation of GRB14 gene

NCBI chr 3:69,976,331...70,091,921
Ensembl chr 3:69,976,339...70,091,921

G

gremlin 1, DAN family BMP antagonist

increases expression

EXP

furan results in increased expression of GREM1 mRNA

NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089

G

gremlin 2, DAN family BMP antagonist

increases expression

EXP

furan results in increased expression of GREM2 mRNA

NCBI chr13:89,310,897...89,403,856
Ensembl chr13:89,310,662...89,404,312

G

grainyhead-like transcription factor 1

increases expression

ISO

furan results in increased expression of GRHL1 mRNA

NCBI chr 6:46,935,947...46,986,126
Ensembl chr 6:46,935,967...46,980,264

G

grainyhead-like transcription factor 2

increases expression

EXP

furan results in increased expression of GRHL2 mRNA

NCBI chr 7:70,280,360...70,415,277
Ensembl chr 7:70,285,310...70,415,274

G

glyoxylate and hydroxypyruvate reductase

increases methylation

EXP

furan results in increased methylation of GRHPR gene

NCBI chr 5:64,029,856...64,039,287
Ensembl chr 5:64,022,368...64,039,276

G

glutamate ionotropic receptor AMPA type subunit 4

increases expression

EXP

furan results in increased expression of GRIA4 mRNA

NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:9,847,052...10,319,881

G

glutamate ionotropic receptor NMDA type subunit 2A

increases methylation

EXP

furan results in increased methylation of GRIN2A gene

NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378

G

glutamate ionotropic receptor NMDA type subunit 2D

decreases expression

EXP

furan results in decreased expression of GRIN2D mRNA

NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:105,444,813...105,481,236

G

glutamate metabotropic receptor 1

increases methylation

EXP

furan results in increased methylation of GRM1 gene

NCBI chr 1:6,878,542...7,273,447
Ensembl chr 1:6,878,545...7,273,443

G

glutamate metabotropic receptor 4

increases expression

EXP

furan results in increased expression of GRM4 mRNA

NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,482,977...5,574,668

G

gamma-secretase activating protein

increases methylation

EXP

furan results in increased methylation of GSAP gene

NCBI chr 4:14,705,237...14,800,057
Ensembl chr 4:14,705,237...14,800,005

G

GSK3B interacting protein

increases expression

EXP

furan results in increased expression of GSKIP mRNA

NCBI chr 6:130,357,241...130,373,221
Ensembl chr 6:130,370,042...130,373,873

G

gelsolin

increases expression

EXP

furan results in increased expression of GSN mRNA

NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:38,982,671...39,035,850

G

glutathione-disulfide reductase

increases expression

EXP

furan results in increased expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione synthetase

increases expression

EXP

furan results in increased expression of GSS mRNA

PMID:25539665 PMID:27402187

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306

G

glutathione S-transferase alpha 2

increases methylation
multiple interactions
increases expression

EXP
ISO

furan results in increased methylation of GSTA2 gene
[Bromodeoxyuridine co-treated with furan] results in increased expression of GSTA1 mRNA
furan results in increased expression of GSTA1 mRNA

PMID:22079235 PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092

G

glutathione S-transferase alpha 3

increases methylation

EXP

furan results in increased methylation of GSTA3 gene

NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654

G

glutathione S-transferase alpha 5

increases methylation
increases expression

EXP

furan results in increased methylation of GSTA5 gene
furan results in increased expression of GSTA5 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:87,985,258...87,997,765

G

glutathione S-transferase, C-terminal domain containing

increases expression

EXP

furan results in increased expression of GSTCD mRNA

NCBI chr 2:224,173,764...224,268,743
Ensembl chr 2:224,173,473...224,265,680

G

glutathione S-transferase mu 1

increases expression

ISO
EXP

furan results in increased expression of GSTM1 mRNA

PMID:20194422 PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase mu 2

decreases expression

EXP

furan results in decreased expression of GSTM2 mRNA

NCBI chr 2:198,312,179...198,316,962

G

glutathione S-transferase mu 4

increases expression

EXP

furan results in increased expression of GSTM4 mRNA

NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638

G

glutathione S-transferase, mu 5

increases expression

ISO

furan results in increased expression of GSTM3 mRNA

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

glutathione S-transferase, mu 5-like

increases expression

EXP

furan results in increased expression of GSTM5 mRNA

NCBI chr 2:198,231,285...198,238,122
Ensembl chr 2:198,232,596...198,238,252

G

glutathione S-transferase, mu 7

decreases expression

EXP

furan results in decreased expression of GSTM7 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:198,254,872...198,260,365
Ensembl chr 2:198,254,875...198,260,373

G

glutathione S-transferase pi 1

increases expression

EXP

furan results in increased expression of GSTP1 mRNA; furan results in increased expression of GSTP1 protein; furan results in increased expression of GSTP2 mRNA

PMID:15120968 PMID:20124500 PMID:25539665 PMID:26194646 PMID:27387713 More...

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase theta 1

increases methylation

EXP

furan results in increased methylation of GSTT1 gene

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019

G

glutathione S-transferase, theta 3

increases expression

EXP

furan results in increased expression of GSTT3 mRNA

NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973

G

glycosyltransferase-like domain containing 1

increases methylation

EXP

furan results in increased methylation of GTDC1 gene

NCBI chr 3:49,176,110...49,571,594
Ensembl chr 3:49,176,110...49,571,843

G

general transcription factor II I

increases methylation

EXP

furan results in increased methylation of GTF2I gene

NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677

G

GTP binding protein 10

increases methylation

EXP

furan results in increased methylation of GTPBP10 gene

NCBI chr 4:29,431,683...29,449,201
Ensembl chr 4:29,431,692...29,449,212

G

GTP binding protein 8

increases methylation
increases expression

EXP

furan results in increased methylation of GTPBP8 gene
furan results in increased expression of GTPBP8 mRNA

PMID:22079235 PMID:25539665

NCBI chr11:69,451,776...69,461,744
Ensembl chr11:69,451,795...69,461,743

G

G-2 and S-phase expressed 1

increases expression

EXP

furan results in increased expression of GTSE1 mRNA

NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661

G

guanylate cyclase activator 1B

increases expression

EXP

furan results in increased expression of GUCA1B mRNA

NCBI chr 9:21,097,274...21,105,107
Ensembl chr 9:21,097,274...21,105,107

G

guanylate cyclase activator 2A

increases expression

EXP

furan results in increased expression of GUCA2A mRNA

NCBI chr 5:138,522,446...138,524,288
Ensembl chr 5:138,522,446...138,524,287

G

guanylate cyclase 1 soluble subunit beta 2

decreases expression

EXP

furan results in decreased expression of GUCY1B2 mRNA

NCBI chr15:40,774,907...40,845,463
Ensembl chr15:40,774,906...40,845,463

G

guanylate cyclase 2C

increases expression

EXP

furan results in increased expression of GUCY2C mRNA

PMID:25539665 PMID:27387713

NCBI chr 4:171,299,715...171,380,296
Ensembl chr 4:171,299,740...171,380,296

G

granzyme M

increases expression

ISO

furan results in increased expression of GZMM mRNA

NCBI chr 7:10,661,683...10,667,448
Ensembl chr 7:10,661,684...10,667,504

G

H19 imprinted maternally expressed transcript

increases expression

EXP

furan results in increased expression of H19 mRNA

NCBI chr 1:207,160,175...207,162,851

G

H1.0 linker histone

decreases expression

EXP

furan results in decreased expression of H1F0 mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006

G

H1.1 linker histone, cluster member

increases methylation

EXP

furan results in increased methylation of H1F1 gene

NCBI chr17:41,762,278...41,794,876

G

H1.2 linker histone, cluster member

increases expression

ISO

furan results in increased expression of H1F2 mRNA

NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317

G

H1.6 linker histone, cluster member

decreases expression

EXP

furan results in decreased expression of H1F6 mRNA

NCBI chr17:41,855,216...41,855,960

G

H2A.J histone

decreases expression

EXP

furan results in decreased expression of H2AJ mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:171,406,922...171,407,406
Ensembl chr 4:171,406,177...171,408,845

G

H2A.X variant histone

increases methylation

EXP

furan results in increased methylation of H2AX gene

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

H2B clustered histone 1

increases expression

EXP

furan results in increased expression of H2BC1 mRNA

NCBI chr17:41,599,912...41,600,381
Ensembl chr17:41,599,211...41,608,681

G

H2B clustered histone 8

increases expression

EXP

furan results in increased expression of H2BC8 mRNA

NCBI chr17:47,404,405...47,405,155

G

H2B clustered histone like 1

increases expression

EXP

furan results in increased expression of H2BC4 mRNA

NCBI chr17:47,448,213...47,448,683
Ensembl chr17:41,859,441...41,869,168
Ensembl chr17:41,859,441...41,869,168

G

H3.3 histone like 1

increases expression

EXP

furan results in increased expression of H3C15 mRNA

NCBI chr 6:63,827,248...63,828,885
Ensembl chr 7:88,378,607...88,392,406

G

H3.4 histone, cluster member

decreases acetylation
decreases methylation

EXP

furan results in decreased acetylation of H3F4 protein
furan results in decreased methylation of H3F4 protein

NCBI chr10:44,240,282...44,240,842

G

2-hydroxyacyl-CoA lyase 1

increases methylation

EXP

furan results in increased methylation of HACL1 gene

NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410

G

hydroxyacyl-CoA dehydrogenase

decreases expression

EXP

furan results in decreased expression of HADH mRNA

NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

EXP

furan results in decreased expression of HADHA mRNA

NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698

G

hepcidin antimicrobial peptide

decreases expression

EXP

furan results in decreased expression of HAMP mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297

G

huntingtin-associated protein 1

increases methylation

EXP

furan results in increased methylation of HAP1 gene

NCBI chr10:85,778,267...85,786,553
Ensembl chr10:85,778,267...85,786,503

G

hyaluronan synthase 1

increases expression

EXP

furan results in increased expression of HAS1 mRNA

NCBI chr 1:67,366,460...67,378,686
Ensembl chr 1:67,366,460...67,378,444

G

HAUS augmin-like complex, subunit 4

increases expression

EXP

furan results in increased expression of HAUS4 mRNA

NCBI chr15:31,964,555...31,976,853
Ensembl chr15:31,964,556...31,975,941

G

hemoglobin alpha, adult chain 2

decreases expression

EXP

furan results in decreased expression of HBA-A2 mRNA

NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141

G

heparin-binding EGF-like growth factor

increases expression

EXP

furan results in increased expression of HBEGF mRNA

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

hypocretin receptor 2

increases methylation

EXP

furan results in increased methylation of HCRTR2 gene

NCBI chr 8:85,870,279...85,986,405
Ensembl chr 8:85,870,279...85,986,405

G

histone deacetylase 1

increases methylation

EXP

furan results in increased methylation of HDAC1 gene

NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387

G

histone deacetylase 11

decreases expression

ISO

furan results in decreased expression of HDAC11 mRNA

NCBI chr 4:125,203,044...125,224,584
Ensembl chr 4:125,202,299...125,224,582

G

histone deacetylase 2

increases methylation

EXP

furan results in increased methylation of HDAC2 gene

NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311

G

histidine decarboxylase

increases expression

EXP

furan results in increased expression of HDC mRNA

NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711

G

HDGF like 3

increases expression

EXP

furan results in increased expression of HDGFL3 mRNA

NCBI chr 1:145,233,996...145,287,115
Ensembl chr 1:145,236,758...145,286,001

G

haloacid dehalogenase-like hydrolase domain containing 3

decreases expression

EXP

furan results in decreased expression of HDHD3 mRNA

NCBI chr 5:80,966,878...80,970,345
Ensembl chr 5:80,954,610...80,970,854

G

heme binding protein 2

increases expression

EXP

furan results in increased expression of HEBP2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:15,014,729...15,021,523
Ensembl chr 1:15,014,729...15,021,523

G

HECT domain E3 ubiquitin protein ligase 2

increases methylation

EXP

furan results in increased methylation of HECTD2 gene

NCBI chr 1:243,687,248...243,756,069
Ensembl chr 1:243,687,923...243,756,069

G

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

increases methylation

EXP

furan results in increased methylation of HECW2 gene

NCBI chr 9:62,853,904...63,247,472
Ensembl chr 9:62,859,645...63,074,758

G

helicase with zinc finger 2

decreases expression

EXP

furan results in decreased expression of HELZ2 mRNA

NCBI chr 3:188,716,370...188,730,776
Ensembl chr 3:188,716,370...188,730,716

G

HemK methyltransferase family member 1

decreases methylation

EXP

furan results in decreased methylation of HEMK1 gene

NCBI chr 8:116,878,317...116,889,342
Ensembl chr 8:116,878,318...116,888,873

G

HEN methyltransferase 1

increases expression

EXP

furan results in increased expression of HENMT1 mRNA

NCBI chr 2:199,258,107...199,291,739
Ensembl chr 2:199,274,480...199,287,822

G

HEPACAM family member 2

increases expression

EXP

furan results in increased expression of HEPACAM2 mRNA

NCBI chr 4:32,400,523...32,435,936
Ensembl chr 4:32,400,558...32,435,512

G

hephaestin

increases expression

EXP

furan results in increased expression of HEPH mRNA

NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453

G

HECT and RLD domain containing E3 ubiquitin protein ligase 3

decreases expression

ISO

furan results in decreased expression of HERC5 mRNA

NCBI chr 4:89,282,374...89,372,656
Ensembl chr 4:89,282,445...89,372,652

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases methylation
increases expression

EXP

furan results in increased methylation of HERPUD1 gene
furan results in increased expression of HERPUD1 mRNA

PMID:22079235 PMID:26194646

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081

G

hes family bHLH transcription factor 7

decreases expression

EXP

furan results in decreased expression of HES7 mRNA

NCBI chr10:54,322,971...54,327,776
Ensembl chr10:54,322,971...54,327,776

G

hexosaminidase subunit beta

increases methylation

EXP

furan results in increased methylation of HEXB gene

NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771

G

HEXIM P-TEFb complex subunit 1

decreases expression

EXP

furan results in decreased expression of HEXIM1 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,560,519...88,580,000

G

homogentisate 1, 2-dioxygenase

decreases expression

EXP

furan results in decreased expression of HGD mRNA

NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767

G

hematopoietically expressed homeobox

decreases expression

EXP

furan results in decreased expression of HHEX mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

EXP

furan results in increased expression of HIBCH mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886

G

hypoxia inducible factor 1 subunit alpha

increases methylation

EXP

furan results in increased methylation of HIF1A gene

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

HIG1 hypoxia inducible domain family, member 1B

increases expression

EXP

furan results in increased expression of HIGD1B mRNA

NCBI chr10:88,302,284...88,304,558
Ensembl chr10:88,302,790...88,304,558

G

histone cluster 1 H2B family member O

increases expression

EXP

furan results in increased expression of HIST1H2BO mRNA

NCBI chr17:47,412,176...47,413,789
Ensembl chr17:47,486,657...47,489,207

G

hexokinase 3

increases methylation

EXP

furan results in increased methylation of HK3 gene

NCBI chr17:9,602,119...9,620,038
Ensembl chr17:9,605,016...9,620,037

G

helicase-like transcription factor

increases expression

EXP

furan results in increased expression of HLTF mRNA

NCBI chr 2:104,478,725...104,538,531
Ensembl chr 2:104,478,772...104,538,818

G

high mobility group box 2

increases expression

EXP

furan results in increased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860

G

high-mobility group box 4

increases methylation

EXP

furan results in increased methylation of HMGB4 gene

NCBI chr 5:145,900,465...145,901,147
Ensembl chr 5:145,881,031...145,903,806

G

3-hydroxy-3-methylglutaryl-CoA lyase

increases expression

EXP

furan results in increased expression of HMGCL mRNA

NCBI chr 5:153,461,738...153,475,552
Ensembl chr 5:153,461,769...153,475,604

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases methylation
multiple interactions
increases expression

EXP
ISO

furan results in increased methylation of HMGCR gene
[Bromodeoxyuridine co-treated with furan] affects the expression of HMGCR mRNA
furan results in increased expression of HMGCR mRNA

PMID:22079235 PMID:24183702 PMID:24910943

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of HMGCS1 gene
furan results in increased expression of HMGCS1 mRNA

PMID:22079235 PMID:24183702

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression

EXP

furan results in decreased expression of HMGCS2 mRNA

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242

G

high mobility group nucleosomal binding domain 3

increases expression

EXP

furan results in increased expression of HMGN3 mRNA

NCBI chr 8:92,902,555...92,939,980

G

heme oxygenase 1

increases expression
multiple interactions

ISO

furan results in increased expression of HMOX1 mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of HMOX1 mRNA

PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

hepatocyte nuclear factor 4, alpha

increases methylation

EXP

furan results in increased methylation of HNF4A gene

NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758

G

histamine N-methyltransferase

increases expression

EXP

furan results in increased expression of HNMT mRNA

NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482

G

heterogeneous nuclear ribonucleoprotein A1

increases expression

EXP

furan results in increased expression of HNRNPA1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085

G

heterogeneous nuclear ribonucleoprotein A2/B1

increases expression

EXP

furan results in increased expression of HNRNPA2B1 mRNA

NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572

G

heterogeneous nuclear ribonucleoprotein H1

affects binding

EXP

furan binds to HNRNPH1 protein

NCBI chr10:35,187,412...35,203,909
Ensembl chr10:35,193,890...35,203,906

G

heterogeneous nuclear ribonucleoprotein H2

increases methylation

EXP

furan results in increased methylation of HNRNPH2 gene

NCBI chr X:102,074,175...102,080,115
Ensembl chr X:102,074,179...102,081,025

G

4-hydroxy-2-oxoglutarate aldolase 1

increases methylation

EXP

furan results in increased methylation of HOGA1 gene

NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:250,806,255...250,833,869

G

HORMA domain containing 1

increases methylation

EXP

furan results in increased methylation of HORMAD1 gene

NCBI chr 2:185,803,572...185,841,449
Ensembl chr 2:185,805,669...185,841,249

G

homeobox A2

decreases methylation
increases expression

EXP

furan results in decreased methylation of HOXA2 gene
furan results in increased expression of HOXA2 mRNA

NCBI chr 4:82,593,389...82,597,589
Ensembl chr 4:82,593,389...82,595,692

G

homeobox A9

increases methylation

EXP

furan results in increased methylation of HOXA9 gene

NCBI chr 4:82,653,847...82,659,958
Ensembl chr 4:82,653,825...82,662,093

G

homeo box B13

increases expression

EXP

furan results in increased expression of HOXB13 mRNA

NCBI chr10:81,657,074...81,659,347
Ensembl chr10:81,657,074...81,659,347

G

homeo box B4

increases methylation

EXP

furan results in increased methylation of HOXB4 gene

NCBI chr10:81,781,090...81,783,672
Ensembl chr10:81,781,090...81,783,666

G

homeo box B7

increases expression

EXP

furan results in increased expression of HOXB7 mRNA

NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,749,097...81,752,550

G

homeo box C4

increases methylation

EXP

furan results in increased methylation of HOXC4 gene

NCBI chr 7:136,049,059...136,051,601
Ensembl chr 7:136,049,059...136,051,601

G

homeo box C5

increases methylation

EXP

furan results in increased methylation of HOXC5 gene

NCBI chr 7:136,029,454...136,032,876
Ensembl chr 7:136,029,454...136,032,876

G

haptoglobin

decreases expression

EXP

furan results in decreased expression of HP mRNA

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518

G

hippocalcin

increases methylation

EXP

furan results in increased methylation of HPCA gene

NCBI chr 5:146,739,978...146,750,961
Ensembl chr 5:146,739,978...146,749,983

G

4-hydroxyphenylpyruvate dioxygenase

increases methylation

EXP

furan results in increased methylation of HPD gene

NCBI chr12:39,042,246...39,053,596
Ensembl chr12:39,042,238...39,053,612

G

4-hydroxyphenylpyruvate dioxygenase-like

increases expression

EXP

furan results in increased expression of HPDL mRNA

NCBI chr 5:135,523,258...135,524,864
Ensembl chr 5:135,523,262...135,535,704

G

15-hydroxyprostaglandin dehydrogenase

increases expression

EXP

furan results in increased expression of HPGD mRNA

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831

G

hematopoietic prostaglandin D synthase

decreases methylation

EXP

furan results in decreased methylation of HPGDS gene

NCBI chr 4:95,698,265...95,727,733
Ensembl chr 4:95,702,392...95,938,501

G

HPS1, biogenesis of lysosomal organelles complex 3 subunit 1

increases expression

EXP

furan results in increased expression of HPS1 mRNA

NCBI chr 1:251,500,427...251,526,529
Ensembl chr 1:251,500,427...251,526,739

G

hemopexin

decreases expression

EXP

furan results in decreased expression of HPX mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156

G

histidine-rich glycoprotein

increases methylation
decreases expression

EXP

furan results in increased methylation of HRG gene
furan results in decreased expression of HRG mRNA

PMID:22079235 PMID:26194646

NCBI chr11:91,559,087...91,573,982
Ensembl chr11:91,559,091...91,573,982

G

histamine receptor H 2

decreases expression

EXP

furan results in decreased expression of HRH2 mRNA

NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041

G

harakiri, BCL2 interacting protein

increases expression

EXP

furan results in increased expression of HRK mRNA

PMID:20562052 PMID:22079235

NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561

G

heparan sulfate-glucosamine 3-sulfotransferase 1

increases expression

EXP

furan results in increased expression of HS3ST1 mRNA

NCBI chr14:75,398,101...75,429,628
Ensembl chr14:75,398,026...75,436,848

G

heparan sulfate 6-O-sulfotransferase 1

increases methylation
decreases expression

EXP

furan results in increased methylation of HS6ST1 gene
furan results in decreased expression of HS6ST1 mRNA

NCBI chr 9:45,779,402...45,818,583
Ensembl chr 9:45,779,019...45,818,582

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression

EXP

furan results in increased expression of HSD11B1 mRNA

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432

G

hydroxysteroid (17-beta) dehydrogenase 2

increases expression
increases methylation

EXP

furan results in increased expression of HSD17B2 mRNA
furan results in increased methylation of HSD17B2 gene

PMID:15120968 PMID:22079235

NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943

G

hydroxysteroid (17-beta) dehydrogenase 6

increases methylation
decreases expression

EXP

furan results in increased methylation of HSD17B6 gene
furan results in decreased expression of HSD17B6 mRNA

PMID:22079235 PMID:26194646

NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

increases expression

EXP

furan results in increased expression of HSD3B6 mRNA

NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

decreases expression

EXP

furan results in decreased expression of HSD3B5 mRNA

PMID:25539665 PMID:26194646

NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118

G

heat shock transcription factor 2 binding protein

increases expression

EXP

furan results in increased expression of HSF2BP mRNA

NCBI chr20:10,035,263...10,121,262
Ensembl chr20:10,035,263...10,121,826

G

heat shock protein 90 alpha family class A member 1

increases expression

ISO

furan results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein family A (Hsp70) member 12B

increases expression

EXP

furan results in increased expression of HSPA12B mRNA

NCBI chr 3:138,799,396...138,817,396
Ensembl chr 3:138,799,398...138,818,935

G

heat shock protein family A (Hsp70) member 1B

increases expression

EXP

furan results in increased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 4 like

increases expression

ISO
EXP

furan results in increased expression of HSPA4L mRNA

PMID:24183702 PMID:25539665

NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986

G

heat shock protein family A (Hsp70) member 5

affects binding
increases expression
multiple interactions
decreases expression

EXP
ISO

furan binds to HSPA5 protein
furan results in increased expression of HSPA5 mRNA; furan results in increased expression of HSPA5 protein
rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of HSPA5 protein]
furan results in decreased expression of HSPA5 mRNA

PMID:22240984 PMID:26194646 PMID:34450210

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 8

affects binding
increases expression

EXP
ISO

furan binds to HSPA8 protein
furan results in increased expression of HSPA8 mRNA

PMID:20194422 PMID:22240984 PMID:24183702 PMID:26194646

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family B (small) member 1

increases expression

ISO
EXP

furan results in increased expression of HSPB1 mRNA

PMID:20194422 PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family B (small) member 3

decreases expression

EXP

furan results in decreased expression of HSPB3 mRNA

NCBI chr 2:47,028,451...47,029,165
Ensembl chr 2:47,024,757...47,029,373

G

heat shock protein family B (small) member 8

increases methylation

EXP

furan results in increased methylation of HSPB8 gene

NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937

G

heat shock protein family B (small) member 9

decreases methylation

EXP

furan results in decreased methylation of HSPB9 gene

NCBI chr10:86,141,603...86,142,248
Ensembl chr10:86,141,269...86,147,839

G

heat shock protein family D (Hsp60) member 1, pseudogene 3

increases expression

EXP

furan results in increased expression of HSPD1-PS3 mRNA

NCBI chr17:55,154,788...55,158,379

G

heat shock protein family H (Hsp110) member 1

increases expression

ISO

furan results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

5-hydroxytryptamine receptor 1F

increases methylation

EXP

furan results in increased methylation of HTR1F gene

NCBI chr11:16,089,266...16,090,665
Ensembl chr11:16,081,053...16,274,580

G

5-hydroxytryptamine receptor 2B

increases expression

EXP

furan results in increased expression of HTR2B mRNA

NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087

G

5-hydroxytryptamine receptor 7

decreases methylation

EXP

furan results in decreased methylation of HTR7 gene

NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230

G

HtrA serine peptidase 1

decreases expression

EXP

furan results in decreased expression of HTRA1 mRNA

NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620

G

HtrA serine peptidase 3

increases expression

EXP

furan results in increased expression of HTRA3 mRNA

NCBI chr14:79,293,535...79,321,936
Ensembl chr14:79,293,541...79,321,936

G

hyaluronidase 1

decreases expression

EXP

furan results in decreased expression of HYAL1 mRNA

NCBI chr 8:117,129,311...117,133,162
Ensembl chr 8:117,129,277...117,133,146

G

hyccin PI4KA lipid kinase complex subunit 2

increases expression

EXP

furan results in increased expression of HYCC2 mRNA

NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186

G

integrin-binding sialoprotein

increases methylation

EXP

furan results in increased methylation of IBSP gene

NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299

G

islet cell autoantigen 1

increases expression

EXP

furan results in increased expression of ICA1 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 4:37,622,759...37,771,055
Ensembl chr 4:37,622,759...37,770,569

G

inhibitor of DNA binding 1

increases expression

ISO

furan results in increased expression of ID1 mRNA

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685

G

inhibitor of DNA binding 2

decreases expression

EXP

furan results in decreased expression of ID2 mRNA

NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961

G

inhibitor of DNA binding 3

increases methylation

EXP

furan results in increased methylation of ID3 gene

NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856

G

inhibitor of DNA binding 4

decreases expression

EXP

furan results in decreased expression of ID4 mRNA

PMID:25539665 PMID:26194646

NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492

G

isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

increases methylation

EXP

furan results in increased methylation of IDH3A gene

NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223

G

immediate early response 5-like

increases expression

EXP

furan results in increased expression of IER5L mRNA

NCBI chr 3:34,141,866...34,143,457
Ensembl chr 3:34,139,672...34,144,452

G

interferon, alpha-inducible protein 27

decreases expression

EXP

furan results in decreased expression of IFI27 mRNA

NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781

G

interferon, alpha-inducible protein 27 like 2A

increases expression

EXP

furan results in increased expression of IFI27L2B mRNA

NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:128,363,658...128,365,146

G

interferon induced transmembrane protein 2

increases expression

EXP

furan results in increased expression of IFITM2 mRNA

NCBI chr 1:205,481,168...205,482,348

G

interferon induced transmembrane protein 6

increases expression

EXP

furan results in increased expression of IFITM6 mRNA

NCBI chr 1:205,546,648...205,547,920

G

interferon-related developmental regulator 2

increases methylation

EXP

furan results in increased methylation of IFRD2 gene

NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836

G

intraflagellar transport 20

increases methylation

EXP

furan results in increased methylation of IFT20 gene

NCBI chr10:63,930,629...63,936,174
Ensembl chr10:63,930,681...63,936,172

G

intraflagellar transport 56

increases expression

EXP

furan results in increased expression of IFT56 mRNA

NCBI chr 4:68,057,530...68,115,494
Ensembl chr 4:68,057,580...68,119,338

G

intraflagellar transport 57

increases methylation

EXP

furan results in increased methylation of IFT57 gene

NCBI chr11:64,528,349...64,593,545
Ensembl chr11:64,528,349...64,593,545

G

intraflagellar transport 70B

increases methylation

EXP

furan results in increased methylation of IFT70B gene

NCBI chr 3:81,263,074...81,265,645

G

intraflagellar transport 80

increases expression

EXP

furan results in increased expression of IFT80 mRNA

NCBI chr 2:155,455,773...155,550,082
Ensembl chr 2:155,455,774...155,550,275

G

intraflagellar transport 88

increases methylation

EXP

furan results in increased methylation of IFT88 gene

NCBI chr15:35,685,678...35,786,875
Ensembl chr15:35,688,927...35,781,634

G

insulin-like growth factor 1

decreases expression

EXP

furan results in decreased expression of IGF1 mRNA

PMID:15120968 PMID:25539665 PMID:26194646

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764

G

insulin-like growth factor 2

decreases expression

EXP

furan results in decreased expression of IGF2 mRNA

NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667

G

insulin-like growth factor 2 mRNA binding protein 2

increases expression

EXP

furan results in increased expression of IGF2BP2 mRNA

NCBI chr11:92,378,908...92,478,893
Ensembl chr11:92,378,908...92,478,867

G

insulin-like growth factor binding protein, acid labile subunit

decreases expression

EXP

furan results in decreased expression of IGFALS mRNA

PMID:25539665 PMID:26194646

NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138

G

insulin-like growth factor binding protein 1

increases expression
decreases expression

ISO
EXP

furan results in increased expression of IGFBP1 mRNA
furan results in decreased expression of IGFBP1 mRNA

PMID:24183702 PMID:26194646 PMID:37517673

NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344

G

insulin-like growth factor binding protein 2

increases expression

EXP

furan results in increased expression of IGFBP2 mRNA

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171

G

insulin-like growth factor binding protein 6

increases methylation
increases expression

EXP

furan results in increased methylation of IGFBP6 gene
furan results in increased expression of IGFBP6 mRNA

PMID:22079235 PMID:27387713

NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795

G

insulin-like growth factor binding protein 7

increases expression

EXP

furan results in increased expression of IGFBP7 mRNA

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620

G

immunoglobulin superfamily, member 10

increases expression

EXP

furan results in increased expression of IGSF10 mRNA

NCBI chr 2:145,725,868...145,754,850
Ensembl chr 2:145,725,878...145,754,579

G

immunoglobulin superfamily, member 11

decreases expression

EXP

furan results in decreased expression of IGSF11 mRNA

NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425

G

immunoglobulin superfamily, member 3

increases expression

EXP

furan results in increased expression of IGSF3 mRNA

NCBI chr 2:191,499,972...191,588,249
Ensembl chr 2:191,500,045...191,588,249

G

immunoglobulin superfamily, member 6

decreases methylation

EXP

furan results in decreased methylation of IGSF6 gene

NCBI chr 1:185,041,462...185,051,956
Ensembl chr 1:185,041,462...185,052,245

G

immunoglobulin superfamily, member 7 like 1

increases expression

EXP

furan results in increased expression of IGSF7L1 mRNA

NCBI chr10:100,673,958...100,681,704
Ensembl chr10:100,655,705...100,682,549

G

interferon gamma induced GTPase

decreases expression

EXP

furan results in decreased expression of IGTP mRNA

NCBI chr10:42,875,047...42,882,866
Ensembl chr10:42,876,790...42,882,858

G

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

increases expression

ISO

furan results in increased expression of IKBKG mRNA

NCBI chr X:157,358,279...157,397,563
Ensembl chr X:157,367,639...157,392,757

G

interleukin 10

decreases expression
multiple interactions

EXP

furan results in decreased expression of IL10 protein
protocatechuic acid inhibits the reaction [furan results in decreased expression of IL10 protein]

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 13 receptor subunit alpha 1

increases methylation

EXP

furan results in increased methylation of IL13RA1 gene

NCBI chr X:120,213,670...120,294,777
Ensembl chr X:120,214,075...120,274,461

G

interleukin 13 receptor subunit alpha 2

increases expression

EXP

furan results in increased expression of IL13RA2 mRNA

NCBI chr X:115,814,620...115,886,080
Ensembl chr X:115,814,622...115,841,455

G

interleukin 17A

increases expression

EXP

furan results in increased expression of IL17A mRNA

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331

G

interleukin 17 receptor E

increases expression

EXP

furan results in increased expression of IL17RE mRNA

NCBI chr 4:148,160,384...148,173,830
Ensembl chr 4:148,159,475...148,173,827

G

interleukin 18

decreases expression
increases expression
multiple interactions

ISO

furan results in decreased expression of IL18 mRNA
furan results in increased expression of IL18 mRNA; furan results in increased expression of IL18 protein
rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein]

PMID:20194422 PMID:34450210

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 1 alpha

decreases expression
increases expression

ISO
EXP

furan results in decreased expression of IL1A mRNA
furan results in increased expression of IL1A mRNA

PMID:20194422 PMID:38160780

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

decreases expression
increases expression
multiple interactions

ISO
EXP

furan results in decreased expression of IL1B mRNA
furan results in increased expression of IL1B mRNA; furan results in increased expression of IL1B protein
rhodioloside inhibits the reaction [furan results in increased expression of IL1B mRNA]; rhodioloside inhibits the reaction [furan results in increased expression of IL1B protein]
protocatechuic acid inhibits the reaction [furan results in increased expression of IL1B protein]

PMID:20194422 PMID:26194646 PMID:32758512 PMID:34450210 PMID:38160780

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor type 1

decreases expression

EXP

furan results in decreased expression of IL1R1 mRNA

NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579

G

interleukin 1 receptor type 2

increases expression

EXP

furan results in increased expression of IL1R2 mRNA

NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:49,877,266...49,920,374

G

interleukin 1 receptor-like 1

decreases methylation
increases expression

EXP

furan results in decreased methylation of IL1RL1 gene
furan results in increased expression of IL1RL1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891

G

interleukin 20 receptor subunit alpha

increases expression

EXP

furan results in increased expression of IL20RA mRNA

NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:16,243,801...16,313,221

G

interleukin 22 receptor subunit alpha 2

increases expression

EXP

furan results in increased expression of IL22RA2 mRNA

NCBI chr 1:16,172,238...16,228,009
Ensembl chr 1:16,184,113...16,197,950

G

interleukin 23 subunit alpha

increases expression

EXP

furan results in increased expression of IL23A mRNA

NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434

G

interleukin 24

increases expression

EXP

furan results in increased expression of IL24 mRNA

NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760

G

interleukin 25

decreases expression

EXP

furan results in decreased expression of IL25 mRNA

NCBI chr15:32,378,750...32,382,141
Ensembl chr15:32,378,750...32,382,141

G

interleukin 33

increases methylation

EXP

furan results in increased methylation of IL33 gene

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901

G

interleukin 3 receptor subunit alpha

increases methylation

EXP

furan results in increased methylation of IL3RA gene

NCBI chr12:21,431,848...21,437,336
Ensembl chr12:21,431,848...21,437,250

G

interleukin 6

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of IL6 mRNA
rhodioloside inhibits the reaction [furan results in increased expression of IL6 mRNA]

PMID:27387713 PMID:34450210

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 receptor

increases expression

EXP

furan results in increased expression of IL6R mRNA

NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221

G

interleukin 7

decreases expression

EXP

furan results in decreased expression of IL7 mRNA

NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389

G

interleukin 9

increases methylation

EXP

furan results in increased methylation of IL9 gene

NCBI chr17:8,117,028...8,120,151
Ensembl chr17:8,117,028...8,120,151

G

immunoglobulin-like domain containing receptor 1

increases expression

EXP

furan results in increased expression of ILDR1 mRNA

PMID:25539665 PMID:27387713

NCBI chr11:77,591,146...77,624,268
Ensembl chr11:77,569,621...77,624,140

G

IMP U3 small nucleolar ribonucleoprotein 4

decreases methylation

EXP

furan results in decreased methylation of IMP4 gene

NCBI chr 9:44,150,029...44,155,167
Ensembl chr 9:44,150,337...44,157,751

G

inositol monophosphatase 1

increases methylation

EXP

furan results in increased methylation of IMPA1 gene

NCBI chr 2:93,370,200...93,391,474
Ensembl chr 2:93,370,299...93,391,468

G

inosine monophosphate dehydrogenase 1

increases expression

EXP

furan results in increased expression of IMPDH1 mRNA

NCBI chr 4:58,767,230...58,782,825
Ensembl chr 4:58,767,230...58,783,124

G

inner centromere protein

increases expression

EXP

furan results in increased expression of INCENP mRNA

NCBI chr 1:215,945,558...216,017,247
Ensembl chr 1:215,948,283...215,977,084

G

inhibin subunit alpha

increases expression

EXP

furan results in increased expression of INHA mRNA

PMID:20562052 PMID:22079235

NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009

G

inhibin subunit beta A

decreases expression

EXP

furan results in decreased expression of INHBA mRNA

PMID:25539665 PMID:26194646

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

inhibin subunit beta C

decreases expression

EXP

furan results in decreased expression of INHBC mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919

G

inhibin subunit beta E

increases expression

ISO

furan results in increased expression of INHBE mRNA

NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519

G

inhibitor of carbonic anhydrase

decreases expression

EXP

furan results in decreased expression of INHCA mRNA

NCBI chr 8:112,715,733...112,753,950
Ensembl chr 8:112,702,085...112,766,829

G

inka box actin regulator 2

increases methylation

EXP

furan results in increased methylation of INKA2 gene

NCBI chr 2:195,873,617...195,888,983
Ensembl chr 2:195,873,497...195,893,605

G

indolethylamine N-methyltransferase

decreases expression

EXP

furan results in decreased expression of INMT mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755

G

inositol polyphosphate-5-phosphatase E

decreases expression

ISO

furan results in decreased expression of INPP5E mRNA

NCBI chr 3:29,614,868...29,627,542
Ensembl chr 3:29,614,868...29,627,542

G

insulin 1

increases methylation

EXP

furan results in increased methylation of INS1 gene

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

insulin 2

decreases expression

EXP

furan results in decreased expression of INS2 mRNA

NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805

G

INSC, spindle orientation adaptor protein

increases expression

ISO

furan results in increased expression of INSC mRNA

NCBI chr 1:178,427,360...178,534,827
Ensembl chr 1:178,427,423...178,535,047

G

insulin induced gene 1

increases expression

ISO

furan results in increased expression of INSIG1 mRNA

PMID:24183702 PMID:24910943

NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778

G

insulin induced gene 2

decreases expression

EXP

furan results in decreased expression of INSIG2 mRNA

NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658

G

insulin-like 6

increases expression

EXP

furan results in increased expression of INSL6 mRNA

NCBI chr 1:236,483,530...236,487,065
Ensembl chr 1:236,483,530...236,487,065

G

integrator complex subunit 14

increases expression

EXP

furan results in increased expression of INTS14 mRNA

NCBI chr 8:74,370,687...74,398,153
Ensembl chr 8:74,371,015...74,396,209

G

integrator complex subunit 2

increases expression

EXP

furan results in increased expression of INTS2 mRNA

NCBI chr10:71,529,021...71,576,529
Ensembl chr10:71,401,151...71,575,206

G

importin 4

increases methylation

EXP

furan results in increased methylation of IPO4 gene

NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241

G

IQ motif containing G

decreases methylation

EXP

furan results in decreased methylation of IQCG gene

NCBI chr11:81,235,204...81,276,249
Ensembl chr11:81,235,090...81,276,249

G

IQ motif and ubiquitin domain containing

increases methylation

EXP

furan results in increased methylation of IQUB gene

NCBI chr 4:53,897,336...53,962,279
Ensembl chr 4:53,897,332...53,954,925

G

inositol 1,4,5-triphosphate receptor associated 1

increases methylation
increases expression

EXP

furan results in increased methylation of IRAG1 gene
furan results in increased expression of IRAG1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:174,416,383...174,528,913
Ensembl chr 1:174,416,385...174,528,851

G

interleukin-1 receptor-associated kinase 1 binding protein 1

increases expression

EXP

furan results in increased expression of IRAK1BP1 mRNA

NCBI chr 8:92,608,468...92,628,377
Ensembl chr 8:92,611,843...92,628,377

G

iron responsive element binding protein 2

increases methylation

EXP

furan results in increased methylation of IREB2 gene

NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520

G

interferon regulatory factor 1

increases expression

EXP

furan results in increased expression of IRF1 mRNA

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947

G

interferon regulatory factor 7

decreases expression

EXP

furan results in decreased expression of IRF7 mRNA

NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023

G

insulin receptor substrate 2

decreases expression

EXP

furan results in decreased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543

G

iroquois homeobox 1

decreases expression

EXP

furan results in decreased expression of IRX1 mRNA

NCBI chr 1:33,123,122...33,128,951
Ensembl chr 1:33,123,122...33,128,951

G

iroquois homeobox 3

decreases expression

EXP

furan results in decreased expression of IRX3 mRNA

NCBI chr19:31,384,803...31,388,241
Ensembl chr19:31,384,833...31,388,238

G

iroquois homeobox 5

increases expression

EXP

furan results in increased expression of IRX5 mRNA

NCBI chr19:30,812,033...30,816,885
Ensembl chr19:30,797,202...30,815,029

G

ISG15 ubiquitin-like modifier

decreases expression

EXP

furan results in decreased expression of ISG15 mRNA

NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656

G

inositol-3-phosphate synthase 1

increases expression

ISO

furan results in increased expression of ISYNA1 mRNA

NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955

G

integrin subunit alpha 3

increases expression

EXP

furan results in increased expression of ITGA3 mRNA

NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901

G

integrin subunit alpha 8

increases expression

EXP

furan results in increased expression of ITGA8 mRNA

NCBI chr17:80,213,139...80,410,633
Ensembl chr17:80,213,143...80,410,633

G

integrin subunit alpha D

increases methylation

EXP

furan results in increased methylation of ITGAD gene

NCBI chr 1:192,190,204...192,218,864
Ensembl chr 1:192,190,204...192,218,864

G

integrin subunit beta 1

increases expression

EXP

furan results in increased expression of ITGB1 mRNA

PMID:15120968 PMID:20562052 PMID:22079235

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269

G

integrin subunit beta 1 binding protein 2

decreases expression

EXP

furan results in decreased expression of ITGB1BP2 mRNA

NCBI chr X:70,612,118...70,617,158
Ensembl chr X:70,612,521...70,617,158

G

integrin subunit beta 4

increases expression

EXP

furan results in increased expression of ITGB4 mRNA

NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932

G

integrin subunit beta 6

increases methylation
increases expression

EXP

furan results in increased methylation of ITGB6 gene
furan results in increased expression of ITGB6 mRNA

PMID:22079235 PMID:27387713

NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:65,456,713...65,530,333

G

integrin subunit beta 7

increases expression

EXP

furan results in increased expression of ITGB7 mRNA

NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:135,226,555...135,243,597

G

integrin subunit beta like 1

increases expression

EXP

furan results in increased expression of ITGBL1 mRNA

NCBI chr15:107,186,792...107,448,335
Ensembl chr15:107,186,689...107,451,098

G

inter-alpha trypsin inhibitor, heavy chain 1

decreases expression

EXP

furan results in decreased expression of ITIH1 mRNA

NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853

G

inter-alpha trypsin inhibitor, heavy chain 3

decreases expression

EXP

furan results in decreased expression of ITIH3 mRNA

NCBI chr16:6,108,378...6,123,609
Ensembl chr16:6,108,382...6,123,374

G

inter-alpha-trypsin inhibitor heavy chain 4

decreases expression

EXP

furan results in decreased expression of ITIH4 mRNA

PMID:15120968 PMID:25539665

NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160

G

inter-alpha-trypsin inhibitor heavy chain 5

increases expression

ISO

furan results in increased expression of ITIH5 mRNA

NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496

G

IL2-inducible T-cell kinase

increases expression

EXP

furan results in increased expression of ITK mRNA

NCBI chr10:31,254,667...31,316,004
Ensembl chr10:31,254,667...31,316,004

G

intelectin 1

increases expression

EXP

furan results in increased expression of ITLN1 mRNA

NCBI chr13:86,464,641...86,490,655
Ensembl chr13:86,464,669...86,490,651

G

isovaleryl-CoA dehydrogenase

affects binding

EXP

furan binds to IVD protein

NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160

G

influenza virus NS1A binding protein

increases expression

EXP

furan results in increased expression of IVNS1ABP mRNA

NCBI chr13:65,977,069...65,996,685
Ensembl chr13:65,977,045...65,997,547

G

izumo sperm-oocyte fusion 1

increases expression

EXP

furan results in increased expression of IZUMO1 mRNA

NCBI chr 1:105,227,603...105,233,357

G

jagged canonical Notch ligand 1

decreases methylation
increases expression

EXP

furan results in decreased methylation of JAG1 gene
furan results in increased expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872

G

Janus kinase 2

increases methylation

EXP

furan results in increased methylation of JAK2 gene

NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762

G

janus kinase and microtubule interacting protein 1

increases expression

EXP

furan results in increased expression of JAKMIP1 mRNA

NCBI chr14:77,871,034...77,991,566
Ensembl chr14:77,871,034...77,991,525

G

Jupiter microtubule associated homolog 2

increases methylation

EXP

furan results in increased methylation of JPT2 gene

NCBI chr10:14,467,652...14,487,769
Ensembl chr10:14,467,661...14,535,664

G

Jrk helix-turn-helix protein

decreases expression

EXP

furan results in decreased expression of JRK mRNA

NCBI chr 7:108,479,646...108,484,329
Ensembl chr 7:108,453,398...108,495,813

G

JRK-like

decreases expression

EXP

furan results in decreased expression of JRKL mRNA

NCBI chr 8:18,505,808...18,508,704
Ensembl chr 8:18,480,815...18,514,962

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases phosphorylation
increases expression
multiple interactions

EXP
ISO

furan results in increased phosphorylation of JUN protein
furan results in increased expression of JUN mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of JUN mRNA

PMID:20124500 PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

JunD proto-oncogene, AP-1 transcription factor subunit

decreases expression

EXP

furan results in decreased expression of JUND mRNA

NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148

G

kidney androgen regulated protein

decreases expression

EXP

furan results in decreased expression of KAP mRNA

NCBI chr 4:168,405,981...168,409,032
Ensembl chr 4:168,405,988...168,409,032

G

lysine acetyltransferase 2A

decreases methylation
decreases expression

EXP

furan results in decreased methylation of KAT2A gene
furan results in decreased expression of KAT2A mRNA

PMID:22079235 PMID:24614236

NCBI chr10:86,132,535...86,140,877
Ensembl chr10:86,132,535...86,140,485

G

katanin catalytic subunit A1 like 1

increases expression

EXP

furan results in increased expression of KATNAL1 mRNA

NCBI chr12:11,130,935...11,192,330
Ensembl chr12:11,139,110...11,194,396

G

katanin regulatory subunit B1 like 1

increases expression

EXP

furan results in increased expression of KATNBL1 mRNA

NCBI chr 3:119,638,068...119,680,179
Ensembl chr 3:119,638,107...119,680,173

G

Kazal-type serine peptidase inhibitor domain 1

increases expression

EXP

furan results in increased expression of KAZALD1 mRNA

PMID:25539665 PMID:27387713

NCBI chr 1:253,888,639...253,892,211
Ensembl chr 1:253,888,783...253,892,305

G

kelch repeat and BTB domain containing 11

increases methylation

EXP

furan results in increased methylation of KBTBD11 gene

NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390

G

kelch repeat and BTB domain containing 2

increases methylation

EXP

furan results in increased methylation of KBTBD2 gene

NCBI chr 4:87,358,133...87,380,399
Ensembl chr 4:87,358,133...87,380,399

G

potassium voltage-gated channel subfamily B member 1

decreases expression

EXP

furan results in decreased expression of KCNB1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 3:176,239,285...176,332,408
Ensembl chr 3:176,242,589...176,332,408

G

potassium voltage-gated channel subfamily D member 1

increases expression

EXP

furan results in increased expression of KCND1 mRNA

NCBI chr X:17,333,612...17,349,255
Ensembl chr X:17,333,612...17,347,799

G

potassium voltage-gated channel subfamily D member 2

decreases expression

EXP

furan results in decreased expression of KCND2 mRNA

NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522

G

potassium voltage-gated channel subfamily E regulatory subunit 3

increases methylation
increases expression

EXP

furan results in increased methylation of KCNE3 gene
furan results in increased expression of KCNE3 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:163,935,991...163,950,162

G

potassium voltage-gated channel modifier subfamily G member 2

increases expression

EXP

furan results in increased expression of KCNG2 mRNA

NCBI chr18:76,017,225...76,085,377
Ensembl chr18:76,018,047...76,083,688

G

potassium voltage-gated channel subfamily H member 3

decreases expression

EXP

furan results in decreased expression of KCNH3 mRNA

NCBI chr 7:132,244,492...132,262,725
Ensembl chr 7:132,244,880...132,262,721

G

potassium voltage-gated channel subfamily H member 6

increases methylation

EXP

furan results in increased methylation of KCNH6 gene

NCBI chr10:91,449,025...91,471,012
Ensembl chr10:91,449,651...91,470,506

G

potassium voltage-gated channel interacting protein 1

decreases expression

EXP

furan results in decreased expression of KCNIP1 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:18,723,726...19,093,025
Ensembl chr10:18,723,726...19,093,087

G

potassium voltage-gated channel interacting protein 4

increases methylation

EXP

furan results in increased methylation of KCNIP4 gene

NCBI chr14:65,593,297...66,743,994
Ensembl chr14:65,593,366...66,743,993

G

potassium inwardly-rectifying channel, subfamily J, member 4

increases methylation

EXP

furan results in increased methylation of KCNJ4 gene

NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:112,922,532...112,954,826

G

potassium two pore domain channel subfamily K member 1

increases expression

EXP

furan results in increased expression of KCNK1 mRNA

NCBI chr19:70,856,985...70,895,053
Ensembl chr19:70,856,985...70,895,051

G

potassium two pore domain channel subfamily K member 10

decreases expression

ISO

furan results in decreased expression of KCNK10 mRNA

NCBI chr 6:123,419,778...123,555,820
Ensembl chr 6:123,423,950...123,555,614

G

potassium two pore domain channel subfamily K member 2

increases methylation

EXP

furan results in increased methylation of KCNK2 gene

NCBI chr13:103,297,387...103,494,686
Ensembl chr13:103,297,393...103,494,686

G

potassium two pore domain channel subfamily K member 5

decreases expression

EXP

furan results in decreased expression of KCNK5 mRNA

NCBI chr15:4,171,625...4,213,896
Ensembl chr15:4,171,610...4,213,897

G

potassium two pore domain channel subfamily K member 6

decreases methylation
increases expression

EXP

furan results in decreased methylation of KCNK6 gene
furan results in increased expression of KCNK6 mRNA

NCBI chr 1:93,652,888...93,661,419

G

potassium calcium-activated channel subfamily M regulatory beta subunit 4

increases expression

EXP

furan results in increased expression of KCNMB4 mRNA

NCBI chr 7:53,952,150...54,005,101
Ensembl chr 7:53,949,881...54,005,281

G

potassium calcium-activated channel subfamily N member 2

decreases expression

EXP

furan results in decreased expression of KCNN2 mRNA

NCBI chr18:40,004,693...40,445,043
Ensembl chr18:40,155,939...40,445,045

G

potassium calcium-activated channel subfamily N member 4

increases expression

EXP

furan results in increased expression of KCNN4 mRNA

NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:89,086,814...89,102,275

G

potassium voltage-gated channel subfamily Q member 3

decreases expression

EXP

furan results in decreased expression of KCNQ3 mRNA

NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:99,619,544...99,914,610

G

potassium channel regulator

decreases expression

EXP

furan results in decreased expression of KCNRG mRNA

NCBI chr15:39,948,920...40,020,937

G

potassium voltage-gated channel, modifier subfamily S, member 1

increases methylation

EXP

furan results in increased methylation of KCNS1 gene

NCBI chr 3:173,255,028...173,262,432
Ensembl chr 3:173,255,028...173,262,346

G

potassium voltage-gated channel, modifier subfamily S, member 3

increases expression

EXP

furan results in increased expression of KCNS3 mRNA

NCBI chr 6:39,527,410...39,584,105
Ensembl chr 6:39,523,777...39,618,848

G

potassium sodium-activated channel subfamily T member 1

increases expression

EXP

furan results in increased expression of KCNT1 mRNA

NCBI chr 3:29,081,071...29,136,902
Ensembl chr 3:29,081,321...29,134,768

G

potassium channel tetramerization domain containing 15

increases expression

EXP

furan results in increased expression of KCTD15 mRNA

NCBI chr 1:96,395,794...96,411,502
Ensembl chr 1:96,395,794...96,410,631

G

potassium channel tetramerization domain containing 16

increases expression

EXP

furan results in increased expression of KCTD16 mRNA

NCBI chr18:32,417,306...32,711,928
Ensembl chr18:32,419,225...32,712,820

G

KDEL endoplasmic reticulum protein retention receptor 3

increases expression

EXP

furan results in increased expression of KDELR3 mRNA

NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858

G

lysine demethylase 1B

increases methylation

EXP

furan results in increased methylation of KDM1B gene

NCBI chr17:17,809,232...17,850,141
Ensembl chr17:17,809,232...17,850,068

G

lysine demethylase 4D

increases methylation

EXP

furan results in increased methylation of KDM4D gene

NCBI chr 8:19,561,253...19,586,412
Ensembl chr 8:19,548,676...19,587,331

G

KH RNA binding domain containing, signal transduction associated 3

increases expression

EXP

furan results in increased expression of KHDRBS3 mRNA

NCBI chr 7:102,726,628...102,884,545
Ensembl chr 7:102,726,843...102,884,541

G

KICSTOR subunit 2

increases methylation

EXP

furan results in increased methylation of KICS2 gene

NCBI chr 7:59,169,703...59,182,974
Ensembl chr 7:59,169,543...59,184,551

G

kinesin family member 11

increases expression

EXP

furan results in increased expression of KIF11 mRNA

NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250

G

kinesin family member 12

increases expression

EXP

furan results in increased expression of KIF12 mRNA

NCBI chr 5:81,611,730...81,620,977
Ensembl chr 5:81,611,734...81,618,369

G

kinesin family member 15

increases methylation

EXP

furan results in increased methylation of KIF15 gene

NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202

G

kinesin family member 18A

increases expression

EXP

furan results in increased expression of KIF18A mRNA

NCBI chr 3:116,219,007...116,279,378
Ensembl chr 3:116,219,007...116,279,227

G

kinesin family member 18B

increases expression

EXP

furan results in increased expression of KIF18B mRNA

NCBI chr10:88,370,520...88,392,388
Ensembl chr10:88,370,524...88,389,691

G

kinesin family member 20A

increases expression

ISO
EXP

furan results in increased expression of KIF20A mRNA

PMID:24183702 PMID:25539665

NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909

G

kinesin family member 20B

increases expression

EXP

furan results in increased expression of KIF20B mRNA

NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:241,840,987...241,896,451

G

kinesin family member 21B

decreases expression

EXP

furan results in decreased expression of KIF21B mRNA

NCBI chr13:50,127,842...50,177,822
Ensembl chr13:50,127,842...50,177,822

G

kinesin family member 22

increases expression

EXP

furan results in increased expression of KIF22 mRNA

NCBI chr 1:191,065,875...191,080,955
Ensembl chr 1:191,065,875...191,080,878

G

kinesin family member 26B

decreases expression

EXP

furan results in decreased expression of KIF26B mRNA

NCBI chr13:92,815,427...93,221,071
Ensembl chr13:92,815,427...93,215,453

G

kinesin family member 2A

increases expression

EXP

furan results in increased expression of KIF2A mRNA

NCBI chr 2:40,101,548...40,164,780
Ensembl chr 2:40,101,548...40,186,618

G

kinesin family member 2C

increases expression

EXP

furan results in increased expression of KIF2C mRNA

NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:135,873,925...135,899,212

G

kinesin family member 3a

increases expression

EXP

furan results in increased expression of KIF3A mRNA

PMID:25539665 PMID:27387713

NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516

G

kinesin family member 9

increases expression

EXP

furan results in increased expression of KIF9 mRNA

NCBI chr 8:119,338,014...119,406,632
Ensembl chr 8:119,338,088...119,383,137

G

kinesin family member C2

decreases expression

ISO

furan results in decreased expression of KIFC2 mRNA

NCBI chr 7:110,261,257...110,269,007
Ensembl chr 7:110,261,009...110,269,005

G

kinesin family member C3

increases expression

EXP

furan results in increased expression of KIFC3 mRNA

PMID:25539665 PMID:26194646

NCBI chr19:9,831,159...9,926,405
Ensembl chr19:9,831,159...9,926,405

G

Kin17 DNA and RNA binding protein

increases methylation

EXP

furan results in increased methylation of KIN gene

NCBI chr17:73,323,189...73,333,542
Ensembl chr17:73,322,801...73,333,542

G

KIT ligand

increases expression

EXP

furan results in increased expression of KITLG mRNA

NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793

G

KLF transcription factor 15

decreases expression

EXP

furan results in decreased expression of KLF15 mRNA

NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373

G

KLF transcription factor 3

decreases expression

EXP

furan results in decreased expression of KLF3 mRNA

NCBI chr14:43,828,387...43,859,418
Ensembl chr14:43,828,387...43,850,826

G

KLF transcription factor 4

increases expression

EXP

furan results in increased expression of KLF4 mRNA

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592

G

KLF transcription factor 5

increases methylation
increases expression

EXP

furan results in increased methylation of KLF5 gene
furan results in increased expression of KLF5 mRNA

PMID:22079235 PMID:27387713

NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262

G

KLF transcription factor 7

decreases expression

EXP

furan results in decreased expression of KLF7 mRNA

NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:72,933,136...73,020,056

G

KLF transcription factor 9

increases expression

EXP

furan results in increased expression of KLF9 mRNA

NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641

G

kelch domain containing 10

increases expression

EXP

furan results in increased expression of KLHDC10 mRNA

NCBI chr 4:59,988,710...60,046,518
Ensembl chr 4:59,988,646...60,046,516

G

kelch-like family member 17

decreases expression

ISO

furan results in decreased expression of KLHL17 mRNA

NCBI chr 5:172,095,701...172,101,945
Ensembl chr 5:172,094,940...172,101,195

G

kelch-like family member 23

increases expression

EXP

furan results in increased expression of KLHL23 mRNA

NCBI chr 3:74,988,778...75,002,347
Ensembl chr 3:74,988,704...75,024,200

G

kelch-like family member 25

increases expression

ISO

furan results in increased expression of KLHL25 mRNA

NCBI chr 1:139,134,655...139,159,898
Ensembl chr 1:139,122,977...139,165,970

G

kelch-like family member 29

decreases expression

ISO

furan results in decreased expression of KLHL29 mRNA

NCBI chr 6:33,805,922...34,110,055
Ensembl chr 6:33,805,922...34,110,055

G

kallikrein 1-related peptidase C6

increases methylation

EXP

furan results in increased methylation of KLK1C6 gene

NCBI chr 1:103,604,150...103,612,366
Ensembl chr 1:103,604,150...103,612,366

G

kallikrein-related peptidase 7

increases methylation

EXP

furan results in increased methylation of KLK7 gene

NCBI chr 1:103,403,206...103,407,907
Ensembl chr 1:103,403,212...103,407,907

G

kallikrein B1

decreases expression

EXP

furan results in decreased expression of KLKB1 mRNA

PMID:25539665 PMID:26194646

NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339

G

killer cell lectin-like receptor, subfamily A, member 1

increases expression

EXP

furan results in increased expression of KLRA1 mRNA

NCBI chr 4:166,291,838...166,313,615
Ensembl chr 4:166,291,841...166,313,615

G

killer cell lectin-like receptor, subfamily A, member 5

increases expression

EXP

furan results in increased expression of KLRA5 mRNA

NCBI chr 4:166,491,210...166,556,087
Ensembl chr 4:166,537,635...166,554,968
Ensembl chr 4:166,537,635...166,554,968

G

killer cell lectin like receptor G1

increases expression

EXP

furan results in increased expression of KLRG1 mRNA

NCBI chr 4:157,127,571...157,139,372
Ensembl chr 4:157,127,571...157,139,372

G

lysine methyltransferase 5C

decreases expression

EXP

furan results in decreased expression of KMT5C mRNA

NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:78,128,325...78,135,931

G

kinetochore scaffold 1

increases expression

EXP

furan results in increased expression of KNL1 mRNA

NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:126,483,544...126,545,774

G

kinetochore-localized astrin/SPAG5 binding protein

increases expression

EXP

furan results in increased expression of KNSTRN mRNA

NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418

G

kinetochore associated 1

increases expression

EXP

furan results in increased expression of KNTC1 mRNA

NCBI chr12:38,429,925...38,500,564
Ensembl chr12:38,429,925...38,500,457

G

karyopherin subunit alpha 1

increases expression

ISO

furan results in increased expression of KPNA1 mRNA

NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067

G

keratin 14

increases expression

EXP

furan results in increased expression of KRT14 mRNA

NCBI chr10:85,638,182...85,642,450

G

keratin 17

increases expression

EXP

furan results in increased expression of KRT17 mRNA

NCBI chr10:85,679,068...85,683,792
Ensembl chr10:85,679,070...85,683,787

G

keratin 18

increases expression

EXP

furan results in increased expression of KRT18 mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

keratin 19

increases expression

EXP

furan results in increased expression of KRT19 mRNA

PMID:26194646 PMID:27387713 PMID:38160780

NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952

G

keratin 20

increases expression

EXP

furan results in increased expression of KRT20 mRNA

PMID:26194646 PMID:27387713

NCBI chr10:84,880,952...84,890,285
Ensembl chr10:84,880,952...84,890,285

G

keratin 23

increases expression

EXP

furan results in increased expression of KRT23 mRNA

NCBI chr10:84,930,603...84,946,929
Ensembl chr10:84,930,603...84,946,929

G

keratin 25

decreases expression

EXP

furan results in decreased expression of KRT25 mRNA

NCBI chr10:84,763,567...84,772,390
Ensembl chr10:84,763,573...84,771,197

G

keratin 28

increases methylation
increases expression

EXP

furan results in increased methylation of KRT28 gene
furan results in increased expression of KRT28 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:84,814,516...84,824,857
Ensembl chr10:84,814,516...84,824,857

G

keratin 33A

increases expression

EXP

furan results in increased expression of KRT33A mRNA

NCBI chr10:85,442,988...85,447,947
Ensembl chr10:85,442,988...85,447,947

G

keratin 39

decreases expression

EXP

furan results in decreased expression of KRT39 mRNA

NCBI chr10:84,970,096...84,976,701
Ensembl chr10:84,970,096...84,976,701

G

keratin 7

increases expression

EXP

furan results in increased expression of KRT7 mRNA

NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786

G

keratin 73

increases methylation

EXP

furan results in increased methylation of KRT73 gene

NCBI chr 7:134,806,517...134,815,028
Ensembl chr 7:134,806,517...134,815,028

G

keratin 75

increases methylation

EXP

furan results in increased methylation of KRT75 gene

NCBI chr 7:134,565,826...134,576,074
Ensembl chr 7:134,565,826...134,576,074

G

keratin 76

increases expression

EXP

furan results in increased expression of KRT76 mRNA

NCBI chr 7:134,895,677...134,904,162
Ensembl chr 7:134,895,677...134,904,162

G

keratin 77

decreases expression

EXP

furan results in decreased expression of KRT77 mRNA

NCBI chr 7:134,868,416...134,880,776
Ensembl chr 7:134,868,416...134,880,776

G

keratin 8

affects binding
increases expression

EXP

furan binds to KRT8 protein
furan results in increased expression of KRT8 mRNA

PMID:22240984 PMID:25539665 PMID:26194646

NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403

G

keratin 8, pseudogene 1

increases expression

EXP

furan results in increased expression of KRT8-PS1 mRNA

G

keratin 81

decreases expression

EXP

furan results in decreased expression of KRT81 mRNA

NCBI chr 7:134,455,840...134,460,971
Ensembl chr 7:134,455,842...134,460,967

G

keratin 82

increases methylation

EXP

furan results in increased methylation of KRT82 gene

NCBI chr 7:134,544,231...134,554,087
Ensembl chr 7:134,543,405...134,554,156

G

keratin 87

increases methylation

EXP

furan results in increased methylation of KRT83 gene

NCBI chr 7:134,426,567...134,433,740
Ensembl chr 7:134,426,567...134,433,740

G

keratinocyte associated protein 3

increases expression

EXP

furan results in increased expression of KRTCAP3 mRNA

NCBI chr 6:30,840,906...30,842,500
Ensembl chr 6:30,840,906...30,842,475

G

kinase suppressor of ras 1

decreases expression

EXP

furan results in decreased expression of KSR1 mRNA

NCBI chr10:64,459,786...64,596,083
Ensembl chr10:64,459,786...64,596,082

G

kynureninase

decreases expression

EXP

furan results in decreased expression of KYNU mRNA

PMID:25539665 PMID:26194646

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014

G

LINE-1 type transposase domain containing 1

increases expression

EXP

furan results in increased expression of L1TD1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:118,488,688...118,501,591
Ensembl chr 5:118,488,688...118,501,591

G

L-2-hydroxyglutarate dehydrogenase

increases expression

EXP

furan results in increased expression of L2HGDH mRNA

NCBI chr 6:93,900,427...93,941,534
Ensembl chr 6:93,900,427...93,941,534

G

ladinin 1

increases expression

EXP

furan results in increased expression of LAD1 mRNA

NCBI chr13:49,801,347...49,815,709
Ensembl chr13:49,800,472...49,815,709

G

laminin subunit beta 2

increases expression

EXP

furan results in increased expression of LAMB2 mRNA

NCBI chr 8:118,056,899...118,069,090
Ensembl chr 8:118,056,935...118,069,090

G

laminin subunit beta 3

increases expression

EXP

furan results in increased expression of LAMB3 mRNA

NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081

G

laminin subunit gamma 2

increases expression

EXP

furan results in increased expression of LAMC2 mRNA

NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102

G

lysosomal-associated membrane protein 1

increases methylation

EXP

furan results in increased methylation of LAMP1 gene

NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159

G

lysosomal protein transmembrane 5

decreases methylation

EXP

furan results in decreased methylation of LAPTM5 gene; furan results in decreased methylation of LAPTM5 promoter

NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927

G

LARGE xylosyl- and glucuronyltransferase 1

increases methylation

EXP

furan results in increased methylation of LARGE1 gene

NCBI chr19:11,609,004...12,057,174
Ensembl chr19:11,609,004...12,054,707

G

LIM and SH3 protein 1

increases methylation

EXP

furan results in increased methylation of LASP1 gene

NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988

G

lymphocyte transmembrane adaptor 1

increases expression

EXP

furan results in increased expression of LAX1 mRNA

NCBI chr13:47,686,840...47,697,396
Ensembl chr13:47,686,849...47,697,460

G

lipopolysaccharide binding protein

decreases expression

EXP

furan results in decreased expression of LBP mRNA

NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518

G

lecithin cholesterol acyltransferase

decreases expression

EXP

furan results in decreased expression of LCAT mRNA

NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081

G

lipocalin 12

increases methylation
decreases expression

EXP

furan results in increased methylation of LCN12 gene
furan results in decreased expression of LCN12 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 3:28,710,557...28,713,537
Ensembl chr 3:28,707,042...28,720,501

G

lipocalin 2

increases expression

ISO

furan results in increased expression of LCN2 mRNA

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842

G

lactate dehydrogenase A

affects binding
increases activity
multiple interactions

EXP
ISO

furan binds to LDHA protein
furan results in increased activity of LDHA protein
furan results in increased expression of and results in increased activity of LDHA protein

PMID:22240984 PMID:37488932

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

lactate dehydrogenase D

increases expression

EXP

furan results in increased expression of LDHD mRNA

NCBI chr19:56,492,827...56,497,695
Ensembl chr19:56,482,924...56,509,197

G

left right determination factor 1

increases methylation
decreases expression

EXP

furan results in increased methylation of LEFTY1 gene
furan results in decreased expression of LEFTY1 mRNA

PMID:22079235 PMID:25539665

NCBI chr13:95,188,091...95,191,488
Ensembl chr13:95,188,091...95,191,488

G

leucine, glutamate and lysine rich 1

increases expression

EXP

furan results in increased expression of LEKR1 mRNA

NCBI chr 2:152,195,003...152,376,389
Ensembl chr 2:152,201,182...152,370,542

G

leptin

decreases expression

EXP

furan results in decreased expression of LEP mRNA

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

leptin receptor

increases methylation

EXP

furan results in increased methylation of LEPR gene

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

leucine zipper and EF-hand containing transmembrane protein 2

increases expression

EXP

furan results in increased expression of LETM2 mRNA

NCBI chr16:73,171,768...73,192,336
Ensembl chr16:73,167,727...73,192,373

G

galectin 1

increases expression

EXP

furan results in increased expression of LGALS1 mRNA

NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:112,361,850...112,368,800

G

galectin 2

increases expression

EXP

furan results in increased expression of LGALS2 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 7:112,283,630...112,290,228
Ensembl chr 7:112,282,822...112,285,392

G

galectin 3 binding protein

increases expression

EXP

furan results in increased expression of LGALS3BP mRNA

NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848

G

galectin 4

increases expression

EXP

furan results in increased expression of LGALS4 mRNA

PMID:26194646 PMID:27387713

NCBI chr 1:93,248,463...93,260,002
Ensembl chr 1:93,252,283...93,259,998

G

galectin 5

increases methylation

EXP

furan results in increased methylation of LGALS5 gene

NCBI chr10:64,351,976...64,355,137
Ensembl chr10:64,351,964...64,355,180

G

galectin 7

increases expression

EXP

furan results in increased expression of LGALS7 mRNA

NCBI chr 1:93,275,092...93,279,529
Ensembl chr 1:93,273,836...93,279,528

G

leucine-rich repeat LGI family, member 3

increases expression

EXP

furan results in increased expression of LGI3 mRNA

NCBI chr15:52,015,317...52,022,445
Ensembl chr15:52,015,230...52,022,443

G

leucine-rich repeat LGI family, member 4

increases methylation

EXP

furan results in increased methylation of LGI4 gene

NCBI chr 1:95,422,461...95,433,296
Ensembl chr 1:95,414,058...95,433,289

G

lengsin, lens protein with glutamine synthetase domain

increases expression

EXP

furan results in increased expression of LGSN mRNA

NCBI chr 9:40,912,398...40,943,955
Ensembl chr 9:40,916,520...40,943,943

G

luteinizing hormone subunit beta

decreases expression
multiple interactions

EXP

furan results in decreased expression of LHB protein
protocatechuic acid inhibits the reaction [furan results in decreased expression of LHB protein]

PMID:24632374 PMID:32758512

NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445

G

LIM homeobox 4

increases expression

EXP

furan results in increased expression of LHX4 mRNA

NCBI chr13:70,423,768...70,477,337
Ensembl chr13:70,427,399...70,467,505

G

LIM homeobox 6

decreases expression

EXP

furan results in decreased expression of LHX6 mRNA

NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559

G

LIM homeobox 8

decreases expression

EXP

furan results in decreased expression of LHX8 mRNA

NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:245,904,712...245,929,376

G

LIF receptor subunit alpha

increases methylation

EXP

furan results in increased methylation of LIFR gene

NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364

G

DNA ligase 1

increases expression

EXP
ISO

furan results in increased expression of LIG1 mRNA

PMID:20194422 PMID:22079235 PMID:25539665

NCBI chr 1:83,243,043...83,281,707
Ensembl chr 1:83,219,545...83,281,708

G

leukocyte immunoglobulin like receptor B4

increases expression

EXP

furan results in increased expression of LILRB4 mRNA

NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326

G

LIM domain containing 2

increases methylation

EXP

furan results in increased methylation of LIMD2 gene

NCBI chr10:91,590,079...91,592,747
Ensembl chr10:91,590,082...91,592,439

G

lin-7 homolog A, crumbs cell polarity complex component

decreases expression

EXP

furan results in decreased expression of LIN7A mRNA

PMID:25539665 PMID:26194646

NCBI chr 7:44,473,568...44,629,074
Ensembl chr 7:44,473,347...44,625,208

G

leucine rich repeat and Ig domain containing 1

increases methylation

EXP

furan results in increased methylation of LINGO1 gene

NCBI chr 8:65,907,275...66,089,485
Ensembl chr 8:65,897,844...66,091,740

G

leucine rich repeat and Ig domain containing 3

increases methylation

EXP

furan results in increased methylation of LINGO3 gene

NCBI chr 7:9,519,252...9,530,675
Ensembl chr 7:9,513,743...9,531,155

G

lipase C, hepatic type

increases methylation
decreases expression

EXP

furan results in increased methylation of LIPC gene
furan results in decreased expression of LIPC mRNA

PMID:22079235 PMID:25539665

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285

G

lipase H

increases expression

EXP

furan results in increased expression of LIPH mRNA

NCBI chr11:92,536,724...92,586,117
Ensembl chr11:92,537,860...92,586,120

G

Lipogenin

increases expression

EXP

furan results in increased expression of LIPOGENIN mRNA

NCBI chr 4:58,321,731...58,322,986

G

LLGL scribble cell polarity complex component 2

increases methylation

EXP

furan results in increased methylation of LLGL2 gene

NCBI chr10:101,549,911...101,585,466
Ensembl chr10:101,549,862...101,585,464

G

LIM and cysteine-rich domains 1

increases expression

EXP

furan results in increased expression of LMCD1 mRNA

NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875

G

leishmanolysin like peptidase

decreases methylation

EXP

furan results in decreased methylation of LMLN gene

NCBI chr11:81,161,330...81,230,972
Ensembl chr11:81,161,330...81,229,447

G

lamin B1

decreases expression

EXP

furan results in decreased expression of LMNB1 mRNA

NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283

G

LIM domain only 1

increases expression

EXP

furan results in increased expression of LMO1 mRNA

NCBI chr 1:172,567,156...172,603,282
Ensembl chr 1:172,567,156...172,603,157

G

LIM domain only 2

increases expression

EXP

furan results in increased expression of LMO2 mRNA

NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:110,809,912...110,833,075

G

ligand of numb-protein X 2

increases methylation

EXP

furan results in increased methylation of LNX2 gene

NCBI chr12:13,119,139...13,184,401
Ensembl chr12:13,119,139...13,184,401

G

LON peptidase N-terminal domain and ring finger 3

increases expression
decreases expression

ISO
EXP

furan results in increased expression of LONRF3 mRNA
furan results in decreased expression of LONRF3 mRNA

PMID:24183702 PMID:26194646

NCBI chr X:120,430,975...120,469,648
Ensembl chr X:120,430,996...120,464,572

G

lysyl oxidase

increases expression

EXP

furan results in increased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

lysyl oxidase-like 1

increases expression

EXP

furan results in increased expression of LOXL1 mRNA

NCBI chr 8:67,587,636...67,612,224
Ensembl chr 8:67,587,636...67,612,224

G

lysyl oxidase-like 3

increases methylation
increases expression

EXP

furan results in increased methylation of LOXL3 gene
furan results in increased expression of LOXL3 mRNA

PMID:22079235 PMID:27387713

NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:117,099,635...117,115,046

G

lysyl oxidase-like 4

decreases expression

EXP

furan results in decreased expression of LOXL4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:251,347,238...251,365,577

G

lysophosphatidic acid receptor 1

increases expression

EXP

furan results in increased expression of LPAR1 mRNA

NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188

G

lysophosphatidic acid receptor 3

decreases expression

EXP

furan results in decreased expression of LPAR3 mRNA

NCBI chr 2:237,785,371...237,854,199
Ensembl chr 2:237,787,766...237,854,197

G

lysophosphatidic acid receptor 6

increases methylation

EXP

furan results in increased methylation of LPAR6 gene

NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783

G

lysophosphatidylcholine acyltransferase 2

increases expression

EXP

furan results in increased expression of LPCAT2 mRNA

NCBI chr19:30,261,369...30,325,715
Ensembl chr19:30,262,676...30,325,775

G

lysophosphatidylcholine acyltransferase 3

increases methylation

EXP

furan results in increased methylation of LPCAT3 gene

NCBI chr 4:159,154,690...159,196,176
Ensembl chr 4:159,154,158...159,196,358

G

lysophosphatidylglycerol acyltransferase 1

decreases expression

EXP

furan results in decreased expression of LPGAT1 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr13:105,825,630...105,896,366
Ensembl chr13:105,820,468...105,896,364

G

lipin 1

increases expression

EXP

furan results in increased expression of LPIN1 mRNA

NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991

G

lipoprotein lipase

decreases methylation
increases expression

EXP

furan results in decreased methylation of LPL gene
furan results in increased expression of LPL mRNA

NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107

G

leupaxin

increases expression

EXP

furan results in increased expression of LPXN mRNA

NCBI chr 1:219,353,319...219,387,743
Ensembl chr 1:219,353,708...219,387,742

G

lecithin retinol acyltransferase

increases expression
decreases methylation

EXP

furan results in increased expression of LRAT mRNA
furan results in decreased methylation of LRAT gene

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148

G

LRAT domain containing 1

increases expression

EXP

furan results in increased expression of LRATD1 mRNA

NCBI chr 6:42,646,515...42,650,988
Ensembl chr 6:42,640,190...42,651,204

G

leucine rich repeats and calponin homology domain containing 1

increases methylation

EXP

furan results in increased methylation of LRCH1 gene

NCBI chr15:56,469,403...56,659,201
Ensembl chr15:56,481,395...56,659,100

G

leucine rich repeat and fibronectin type III domain containing 3

decreases expression
increases methylation

EXP

furan results in decreased expression of LRFN3 mRNA
furan results in increased methylation of LRFN3 gene

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 1:94,744,315...94,751,001
Ensembl chr 1:94,744,321...94,751,178

G

leucine-rich repeat, Ig-like and transmembrane domains 1

decreases expression

ISO

furan results in decreased expression of LRIT1 mRNA

NCBI chr16:12,842,339...12,850,266
Ensembl chr16:12,842,339...12,852,035

G

LDL receptor related protein 1

decreases expression

EXP

furan results in decreased expression of LRP1 mRNA

NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196

G

LDL receptor related protein 2

decreases expression

EXP

furan results in decreased expression of LRP2 mRNA

NCBI chr 3:74,597,148...74,754,535
Ensembl chr 3:74,597,148...74,754,535

G

leucine rich repeat containing 17

increases expression

EXP

furan results in increased expression of LRRC17 mRNA

NCBI chr 4:14,393,632...14,424,048
Ensembl chr 4:14,393,640...14,424,048

G

leucine rich repeat containing 24

increases expression

ISO
EXP

furan results in increased expression of LRRC24 mRNA

PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr 7:110,317,935...110,325,201
Ensembl chr 7:110,317,020...110,325,074

G

leucine rich repeat containing 27

increases methylation

EXP

furan results in increased methylation of LRRC27 gene

NCBI chr 1:203,433,463...203,464,683
Ensembl chr 1:203,434,355...203,464,676

G

leucine rich repeat containing 36

decreases expression

EXP

furan results in decreased expression of LRRC36 mRNA

NCBI chr19:50,201,944...50,252,338
Ensembl chr19:50,201,987...50,252,338

G

leucine rich repeat containing 46

increases expression

EXP

furan results in increased expression of LRRC46 mRNA

NCBI chr10:82,517,767...82,530,011
Ensembl chr10:82,517,769...82,532,378

G

leucine rich repeat containing 49

increases expression

EXP

furan results in increased expression of LRRC49 mRNA

NCBI chr 8:69,948,962...70,056,579
Ensembl chr 8:69,948,972...70,079,636

G

leucine rich repeat containing 51

increases expression

EXP

furan results in increased expression of LRRC51 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:165,690,617...165,709,837
Ensembl chr 1:165,690,111...165,698,842

G

leucine rich repeat containing 52

increases methylation

EXP

furan results in increased methylation of LRRC52 gene

NCBI chr13:82,130,174...82,153,569
Ensembl chr13:82,130,175...82,153,894

G

leucine rich repeat containing 59

increases expression

EXP

furan results in increased expression of LRRC59 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079

G

leucine rich repeat containing 8 VRAC subunit A

decreases expression

EXP

furan results in decreased expression of LRRC8A mRNA

NCBI chr 3:33,902,299...33,934,989
Ensembl chr 3:33,908,268...33,933,625

G

leucine rich repeat containing 8 VRAC subunit E

increases expression

EXP

furan results in increased expression of LRRC8E mRNA

NCBI chr12:7,376,103...7,387,250
Ensembl chr12:7,380,585...7,387,249

G

leucine-rich repeats and IQ motif containing 3

increases expression

EXP

furan results in increased expression of LRRIQ3 mRNA

NCBI chr 2:246,778,759...246,871,284
Ensembl chr 2:246,778,984...246,880,668

G

leucine-rich repeat kinase 2

increases expression

EXP

furan results in increased expression of LRRK2 mRNA

NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239

G

leucine-rich repeats and transmembrane domains 1

decreases expression

ISO

furan results in decreased expression of LRTM1 mRNA

NCBI chr16:4,216,947...4,224,447

G

leucine-rich repeats and transmembrane domains 2

decreases expression

EXP

furan results in decreased expression of LRTM2 mRNA

NCBI chr 4:154,158,165...154,180,389
Ensembl chr 4:154,158,168...154,167,641

G

leucine rich transmembrane and O-methyltransferase domain containing

increases expression

EXP

furan results in increased expression of LRTOMT mRNA

NCBI chr 1:165,678,654...165,680,703
Ensembl chr 1:165,678,654...165,680,703

G

lymphotoxin beta

increases expression

EXP

furan results in increased expression of LTB mRNA

NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054

G

leukotriene B4 receptor

increases expression

ISO

furan results in increased expression of LTB4R1 mRNA

NCBI chr15:33,233,120...33,235,636
Ensembl chr15:33,232,820...33,235,637

G

latent transforming growth factor beta binding protein 1

increases expression

EXP

furan results in increased expression of LTBP1 mRNA

NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036

G

latent transforming growth factor beta binding protein 2

increases expression

EXP

furan results in increased expression of LTBP2 mRNA

NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298

G

latent transforming growth factor beta binding protein 3

increases expression
decreases methylation

EXP

furan results in increased expression of LTBP3 mRNA
furan results in decreased methylation of LTBP3 gene

NCBI chr 1:212,458,362...212,475,302
Ensembl chr 1:212,459,185...212,475,302

G

leukotriene C4 synthase

decreases expression

EXP

furan results in decreased expression of LTC4S mRNA

NCBI chr10:35,060,002...35,066,466
Ensembl chr10:35,061,437...35,063,768

G

lumican

increases expression

EXP

furan results in increased expression of LUM mRNA

NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:34,245,360...34,252,508

G

leucine rich adaptor protein 1

decreases expression

EXP

furan results in decreased expression of LURAP1 mRNA

NCBI chr 5:134,855,643...134,865,366
Ensembl chr 5:134,855,224...134,865,459

G

latexin

increases expression

EXP

furan results in increased expression of LXN mRNA

NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488

G

Ly49 stimulatory receptor 7

increases expression

EXP

furan results in increased expression of LY49S7 mRNA

NCBI chr 4:166,491,218...166,511,293
Ensembl chr 4:166,491,504...166,509,673

G

immunoreceptor Ly49si2

increases expression

EXP

furan results in increased expression of LY49SI2 mRNA

NCBI chr 4:165,358,092...165,410,591

G

lymphocyte antigen 6 family member A

increases expression

EXP

furan results in increased expression of LY6AL mRNA

NCBI chr 7:109,064,222...109,067,757

G

lymphocyte antigen 6 family member D

increases expression

ISO

furan results in increased expression of LY6D mRNA

NCBI chr 7:108,532,207...108,533,943
Ensembl chr 7:108,532,215...108,533,716

G

lymphocyte antigen 6 family member H

increases expression
decreases methylation

EXP

furan results in increased expression of LY6H mRNA
furan results in decreased methylation of LY6H gene

NCBI chr 7:109,139,527...109,142,108
Ensembl chr 7:109,139,527...109,246,799

G

LYL1, basic helix-loop-helix family member

increases expression

EXP

furan results in increased expression of LYL1 mRNA

NCBI chr19:40,356,967...40,359,834
Ensembl chr19:40,354,819...40,359,834

G

Ly6/neurotoxin 1

decreases expression

EXP

furan results in decreased expression of LYNX1 mRNA

NCBI chr 7:108,521,783...108,527,012
Ensembl chr 7:108,521,780...108,527,130

G

Ly6/Plaur domain containing 1

increases expression

EXP

furan results in increased expression of LYPD1 mRNA

NCBI chr13:39,874,937...39,922,385
Ensembl chr13:39,879,096...39,922,338

G

Ly6/Plaur domain containing 4

increases methylation

EXP

furan results in increased methylation of LYPD4 gene

NCBI chr 1:89,588,368...89,594,287
Ensembl chr 1:89,588,368...89,593,890

G

Ly6/Plaur domain containing 6B

increases expression

EXP

furan results in increased expression of LYPD6B mRNA

NCBI chr 3:54,608,320...54,769,974
Ensembl chr 3:54,757,444...54,769,974

G

Ly6/Plaur domain containing 8

increases expression

EXP

furan results in increased expression of LYPD8 mRNA

NCBI chr10:43,062,261...43,073,108
Ensembl chr10:43,065,186...43,073,105

G

lysophospholipase 2

increases methylation

EXP

furan results in increased methylation of LYPLA2 gene

NCBI chr 5:153,481,973...153,486,692
Ensembl chr 5:153,481,974...153,486,601

G

LysM domain containing 2

increases expression

ISO

furan results in increased expression of LYSMD2 mRNA

NCBI chr 8:85,259,443...85,274,876
Ensembl chr 8:85,259,410...85,275,241

G

lysozyme 2

increases expression

EXP

furan results in increased expression of LYZ2 mRNA

PMID:26194646 PMID:27387713

NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011

G

leucine zipper tumor suppressor 1

increases expression

EXP

furan results in increased expression of LZTS1 mRNA

NCBI chr16:25,309,502...25,364,942
Ensembl chr16:25,309,507...25,364,940

G

leucine zipper tumor suppressor 2

increases expression

EXP

furan results in increased expression of LZTS2 mRNA

NCBI chr 1:253,824,073...253,837,614
Ensembl chr 1:253,829,119...253,837,632

G

mab-21 like 2

decreases expression

EXP

furan results in decreased expression of MAB21L2 mRNA

NCBI chr 2:174,244,538...174,247,620
Ensembl chr 2:174,238,828...174,252,064

G

mitotic arrest deficient 2 like 1

increases expression

EXP

furan results in increased expression of MAD2L1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222

G

MAF bZIP transcription factor B

decreases expression

EXP

furan results in decreased expression of MAFB mRNA

NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975

G

MAGE family member B3

decreases expression

EXP

furan results in decreased expression of MAGEB3 mRNA

NCBI chr X:54,816,254...54,817,249
Ensembl chr X:54,816,254...54,817,249

G

MAGE family member D2

increases expression

EXP

furan results in increased expression of MAGED2 mRNA

NCBI chr X:23,160,928...23,364,994
Ensembl chr X:23,160,931...23,169,104

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

decreases expression

EXP

furan results in decreased expression of MAGI2 mRNA

NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199

G

MAGI family member, X-linked

increases methylation

EXP

furan results in increased methylation of MAGIX gene

NCBI chr X:17,496,092...17,504,370
Ensembl chr X:17,496,225...17,504,369

G

magnesium transporter 1

increases methylation

EXP

furan results in increased methylation of MAGT1 gene

NCBI chr X:75,104,040...75,145,247
Ensembl chr X:75,106,172...75,145,365

G

mal, T-cell differentiation protein

increases expression

EXP

furan results in increased expression of MAL mRNA

NCBI chr 3:135,317,664...135,341,423
Ensembl chr 3:135,317,664...135,341,423

G

mal, T-cell differentiation protein 2

increases expression

ISO

furan results in increased expression of MAL2 mRNA

NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:87,790,239...87,850,403

G

mal, T-cell differentiation protein-like

increases expression

EXP

furan results in increased expression of MALL mRNA

NCBI chr 3:135,381,180...135,404,136
Ensembl chr 3:135,377,410...135,404,066

G

mannosidase, alpha, class 2B, member 1

decreases expression

EXP

furan results in decreased expression of MAN2B1 mRNA

PMID:25539665 PMID:26194646

NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246

G

mannosidase, alpha, class 2C, member 1

increases methylation

EXP

furan results in increased methylation of MAN2C1 gene

NCBI chr 8:66,434,480...66,445,649
Ensembl chr 8:66,434,421...66,445,648

G

mannosidase, endo-alpha

increases methylation

EXP

furan results in increased methylation of MANEA gene

NCBI chr 5:44,992,937...45,015,084
Ensembl chr 5:44,992,937...45,015,084

G

mitogen-activated protein kinase kinase kinase 1

increases methylation
decreases expression

EXP

furan results in increased methylation of MAP3K1 gene
furan results in decreased expression of MAP3K1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897

G

mitogen-activated protein kinase kinase kinase 11

increases methylation

EXP

furan results in increased methylation of MAP3K11 gene

NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983

G

mitogen activated protein kinase kinase kinase 12

increases methylation

EXP

furan results in increased methylation of MAP3K12 gene

NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137

G

mitogen-activated protein kinase kinase kinase 5

increases expression
multiple interactions
increases phosphorylation

EXP
ISO

furan results in increased expression of MAP3K5 mRNA
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAP3K5 protein]

PMID:26194646 PMID:34450210

NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898

G

mitogen-activated protein kinase kinase kinase 6

increases expression

EXP

furan results in increased expression of MAP3K6 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111

G

mitogen-activated protein kinase kinase kinase 8

increases expression

EXP

furan results in increased expression of MAP3K8 mRNA

NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452

G

mitogen-activated protein kinase kinase kinase kinase 4

increases methylation

EXP

furan results in increased methylation of MAP4K4 gene

NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353

G

MAP7 domain containing 1

decreases expression

EXP

furan results in decreased expression of MAP7D1 mRNA

NCBI chr 5:143,812,467...143,837,597
Ensembl chr 5:143,811,924...143,837,021

G

mitogen activated protein kinase 1

increases phosphorylation
increases expression
multiple interactions

ISO
EXP

furan results in increased phosphorylation of MAPK1 protein
furan results in increased expression of MAPK1 mRNA
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK1 protein]

PMID:34450210 PMID:38160780

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 13

increases expression

EXP

furan results in increased expression of MAPK13 mRNA

NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191

G

mitogen-activated protein kinase 15

increases methylation
increases expression

EXP

furan results in increased methylation of MAPK15 gene
furan results in increased expression of MAPK15 mRNA

PMID:22079235 PMID:25539665

NCBI chr 7:109,575,619...109,595,339
Ensembl chr 7:109,575,561...109,595,346

G

mitogen activated protein kinase 3

increases phosphorylation
increases expression
multiple interactions

ISO
EXP

furan results in increased phosphorylation of MAPK3 protein
furan results in increased expression of MAPK3 mRNA
rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK3 protein]

PMID:34450210 PMID:38160780

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 4

increases expression

EXP

furan results in increased expression of MAPK4 mRNA

NCBI chr18:69,788,058...69,937,524
Ensembl chr18:69,788,060...69,837,037

G

mitogen-activated protein kinase 8

multiple interactions
increases phosphorylation

ISO

rhodioloside inhibits the reaction [furan results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 8 interacting protein 1

decreases expression

EXP

furan results in decreased expression of MAPK8IP1 mRNA

NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368

G

membrane associated ring-CH-type finger 1

decreases expression

EXP

furan results in decreased expression of MARCHF1 mRNA

NCBI chr16:28,022,159...28,880,872
Ensembl chr16:28,022,159...28,881,054

G

membrane associated ring-CH-type finger 10

increases methylation

EXP

furan results in increased methylation of MARCHF10 gene

NCBI chr10:90,832,647...90,975,700
Ensembl chr10:90,832,648...90,922,722

G

myristoylated alanine rich protein kinase C substrate

increases expression

EXP

furan results in increased expression of MARCKS mRNA

PMID:26194646 PMID:27387713

NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882

G

MARCKS-like 1

increases expression

EXP

furan results in increased expression of MARCKSL1 mRNA

NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417

G

MBL associated serine protease 1

decreases expression

EXP

furan results in decreased expression of MASP1 mRNA

PMID:25539665 PMID:26194646

NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470

G

microtubule associated serine/threonine kinase-like

increases expression

EXP

furan results in increased expression of MASTL mRNA

NCBI chr17:90,158,592...90,195,550
Ensembl chr17:90,160,068...90,195,564

G

methionine adenosyltransferase 1A

affects binding

EXP

furan binds to MAT1A protein

NCBI chr16:17,017,168...17,035,368
Ensembl chr16:17,016,030...17,035,367

G

methionine adenosyltransferase 2 non-catalytic beta subunit

decreases methylation

EXP

furan results in decreased methylation of MAT2B gene

NCBI chr10:25,609,202...25,626,694
Ensembl chr10:25,609,204...25,625,176

G

megakaryocyte-associated tyrosine kinase

increases expression

EXP

furan results in increased expression of MATK mRNA

NCBI chr 7:9,107,711...9,116,864
Ensembl chr 7:9,107,722...9,112,746

G

matrilin 4

increases expression

EXP

furan results in increased expression of MATN4 mRNA

NCBI chr 3:173,539,966...173,554,984
Ensembl chr 3:173,539,966...173,554,984

G

MAU2 sister chromatid cohesion factor

decreases expression

EXP

furan results in decreased expression of MAU2 mRNA

NCBI chr16:19,417,812...19,448,922
Ensembl chr16:19,417,613...19,445,841

G

mannose binding lectin 2

increases methylation
decreases expression

EXP

furan results in increased methylation of MBL2 gene
furan results in decreased expression of MBL2 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546

G

metallo-beta-lactamase domain containing 2

increases methylation

EXP

furan results in increased methylation of MBLAC2 gene

NCBI chr 2:13,721,752...13,764,558
Ensembl chr 2:13,721,360...13,766,626

G

membrane bound O-acyltransferase domain containing 1

increases expression

EXP

furan results in increased expression of MBOAT1 mRNA

NCBI chr17:34,540,032...34,653,705
Ensembl chr17:34,540,041...34,653,698

G

minichromosome maintenance 10 replication initiation factor

increases expression

EXP

furan results in increased expression of MCM10 mRNA

NCBI chr17:78,172,049...78,197,644
Ensembl chr17:78,175,398...78,197,636

G

minichromosome maintenance complex component 2

increases expression

EXP

furan results in increased expression of MCM2 mRNA

PMID:20562052 PMID:22079235 PMID:25539665

NCBI chr 4:122,903,679...122,918,205
Ensembl chr 4:122,903,682...122,918,094

G

minichromosome maintenance complex component 3

increases expression

EXP

furan results in increased expression of MCM3 mRNA

NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746

G

minichromosome maintenance complex component 4

increases expression

EXP

furan results in increased expression of MCM4 mRNA

NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536

G

minichromosome maintenance complex component 5

increases expression

EXP

furan results in increased expression of MCM5 mRNA

NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758

G

minichromosome maintenance complex component 6

increases expression

ISO
EXP

furan results in increased expression of MCM6 mRNA

PMID:20124500 PMID:24183702 PMID:25539665

NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467

G

minichromosome maintenance 8 homologous recombination repair factor

increases expression

EXP

furan results in increased expression of MCM8 mRNA

NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891

G

mucolipin TRP cation channel 3

decreases expression

EXP

furan results in decreased expression of MCOLN3 mRNA

NCBI chr 2:237,596,544...237,705,770
Ensembl chr 2:237,626,302...237,705,769

G

mast cell protease 1

increases expression

EXP

furan results in increased expression of MCPT2 mRNA

NCBI chr15:33,841,606...33,844,174
Ensembl chr15:33,841,606...33,844,174

G

mast cell protease 10

decreases expression

EXP

furan results in decreased expression of MCPT10 mRNA

NCBI chr15:33,885,728...33,888,787
Ensembl chr15:33,885,731...33,888,756

G

mast cell protease 8

decreases expression

EXP

furan results in decreased expression of MCPT8 mRNA

NCBI chr15:33,769,575...33,772,633

G

mast cell protease 9

decreases expression

EXP

furan results in decreased expression of MCPT9 mRNA

NCBI chr15:33,827,348...33,830,396
Ensembl chr15:33,827,378...33,830,396

G

MAPK regulated co-repressor interacting protein 2

increases expression

EXP

furan results in increased expression of MCRIP2 mRNA

NCBI chr10:15,388,325...15,393,302
Ensembl chr10:15,388,325...15,398,730

G

MCTS family member 2

decreases expression

EXP

furan results in decreased expression of MCTS2 mRNA

NCBI chr 3:161,623,597...161,624,375

G

MyoD family inhibitor

increases expression

EXP

furan results in increased expression of MDFI mRNA

NCBI chr 9:20,654,359...20,672,768
Ensembl chr 9:20,654,417...20,672,767

G

malate dehydrogenase 1

affects binding

EXP

furan binds to MDH1 protein

NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232

G

malate dehydrogenase 1B

increases expression

EXP

furan results in increased expression of MDH1B mRNA

NCBI chr 9:72,614,185...72,661,820
Ensembl chr 9:72,613,340...72,661,745

G

Mdm1 nuclear protein

increases expression

EXP

furan results in increased expression of MDM1 mRNA

NCBI chr 7:55,615,459...55,651,889
Ensembl chr 7:55,615,608...55,651,888

G

MDM2 proto-oncogene

increases expression

EXP

furan results in increased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

malic enzyme 1

increases expression
decreases expression

EXP

furan results in increased expression of ME1 mRNA
furan results in decreased expression of ME1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275

G

malic enzyme 3

decreases expression

EXP

furan results in decreased expression of ME3 mRNA

NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:152,946,628...153,148,026

G

mediator complex subunit 1

increases methylation

EXP

furan results in increased methylation of MED1 gene

NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,641,862...83,685,545

G

mediator complex subunit 19

increases methylation

EXP

furan results in increased methylation of MED19 gene

NCBI chr 3:90,168,829...90,179,351
Ensembl chr 3:90,168,829...90,179,351

G

MEFV innate immunity regulator, pyrin

increases expression

EXP

furan results in increased expression of MEFV mRNA

NCBI chr10:12,288,514...12,303,337
Ensembl chr10:12,293,782...12,303,333

G

meiosis specific with OB-fold

increases expression

EXP

furan results in increased expression of MEIOB mRNA

NCBI chr10:14,336,869...14,369,566
Ensembl chr10:14,338,288...14,369,565

G

maternal embryonic leucine zipper kinase

increases methylation
increases expression

EXP

furan results in increased methylation of MELK gene
furan results in increased expression of MELK mRNA

PMID:22079235 PMID:25539665

NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247

G

mesenchyme homeobox 1

increases expression

EXP

furan results in increased expression of MEOX1 mRNA

NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976

G

mesenchyme homeobox 2

decreases expression

EXP

furan results in decreased expression of MEOX2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:59,583,785...59,644,700

G

meprin A subunit beta

increases expression

EXP

furan results in increased expression of MEP1B mRNA

NCBI chr18:12,641,041...12,667,759
Ensembl chr18:12,641,041...12,667,755

G

MET proto-oncogene, receptor tyrosine kinase

increases methylation

EXP

furan results in increased methylation of MET gene

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

methionyl aminopeptidase 1

increases methylation

EXP

furan results in increased methylation of METAP1 gene

NCBI chr 2:229,664,677...229,697,730
Ensembl chr 2:229,664,677...229,719,084

G

methionyl aminopeptidase 2

increases methylation

EXP

furan results in increased methylation of METAP2 gene

NCBI chr 7:30,299,433...30,327,477
Ensembl chr 7:30,299,433...30,327,521

G

meteorin-like, glial cell differentiation regulator

increases expression

EXP

furan results in increased expression of METRNL mRNA

NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135

G

methyltransferase like 25B

increases methylation

EXP

furan results in increased methylation of METTL25B gene

NCBI chr 2:175,686,483...175,695,137
Ensembl chr 2:175,686,539...175,695,137

G

microfibril associated protein 2

increases expression

EXP

furan results in increased expression of MFAP2 mRNA

NCBI chr 5:158,595,121...158,603,283
Ensembl chr 5:158,597,512...158,610,656

G

microfibril associated protein 4

increases expression

EXP

furan results in increased expression of MFAP4 mRNA

NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740

G

microfibril associated protein 5

increases expression

EXP

furan results in increased expression of MFAP5 mRNA

NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:157,395,597...157,422,448

G

milk fat globule EGF and factor V/VIII domain containing

increases expression

EXP

furan results in increased expression of MFGE8 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431

G

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

increases expression

EXP

furan results in increased expression of MFNG mRNA

NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129

G

major facilitator superfamily domain containing 13A

increases methylation

EXP

furan results in increased methylation of MFSD13A gene

NCBI chr 1:255,158,338...255,177,731
Ensembl chr 1:255,152,543...255,177,733

G

major facilitator superfamily domain containing 4A

increases methylation

EXP

furan results in increased methylation of MFSD4A gene

NCBI chr13:46,015,321...46,062,633
Ensembl chr13:46,021,659...46,062,633

G

major facilitator superfamily domain containing 4B1

decreases expression

EXP

furan results in decreased expression of MFSD4B1 mRNA

NCBI chr20:44,991,384...45,004,590
Ensembl chr20:44,991,384...45,006,161

G

major facilitator superfamily domain containing 4B3

decreases expression

EXP

furan results in decreased expression of MFSD4B3 mRNA

NCBI chr20:44,923,703...44,948,921
Ensembl chr20:44,925,502...44,949,154

G

major facilitator superfamily domain containing 6

increases methylation
decreases expression

EXP

furan results in increased methylation of MFSD6 gene
furan results in decreased expression of MFSD6 mRNA

PMID:22079235 PMID:27387713

NCBI chr 9:56,265,152...56,350,449
Ensembl chr 9:56,265,237...56,350,446

G

major facilitator superfamily domain containing 8

increases methylation

EXP

furan results in increased methylation of MFSD8 gene

NCBI chr 2:125,749,994...125,784,689
Ensembl chr 2:125,749,994...125,785,919

G

mitochondria-localized glutamic acid-rich protein

increases methylation

EXP

furan results in increased methylation of MGARP gene

NCBI chr 2:137,582,152...137,590,294
Ensembl chr 2:137,582,152...137,590,481

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

increases expression

EXP

furan results in increased expression of MGAT4A mRNA

NCBI chr 9:47,169,229...47,282,577
Ensembl chr 9:47,169,232...47,282,574

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

decreases expression

EXP

furan results in decreased expression of MGAT4B mRNA

NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309

G

O-6-methylguanine-DNA methyltransferase

increases expression

EXP

furan results in increased expression of MGMT mRNA

PMID:22507866 PMID:26194646

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482

G

matrix Gla protein

increases expression

EXP

furan results in increased expression of MGP mRNA

NCBI chr 4:171,497,472...171,500,888
Ensembl chr 4:171,497,471...171,500,859

G

mahogunin ring finger 1

increases methylation

EXP

furan results in increased methylation of MGRN1 gene

NCBI chr10:11,142,626...11,194,773
Ensembl chr10:11,145,690...11,194,805

G

microsomal glutathione S-transferase 1

increases methylation

EXP

furan results in increased methylation of MGST1 gene

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

MIA SH3 domain containing

increases expression

EXP

furan results in increased expression of MIA mRNA

PMID:25539665 PMID:27387713

NCBI chr 1:91,601,326...91,603,019
Ensembl chr 1:91,601,327...91,603,019

G

microtubule associated monooxygenase, calponin and LIM domain containing 2

increases expression

EXP

furan results in increased expression of MICAL2 mRNA

NCBI chr 1:175,780,441...175,965,157
Ensembl chr 1:175,825,596...175,905,155

G

mitochondrial calcium uptake 2

increases expression

EXP

furan results in increased expression of MICU2 mRNA

NCBI chr15:36,180,413...36,262,429
Ensembl chr15:36,170,832...36,262,686

G

MID1 interacting protein 1

increases methylation
decreases expression

EXP

furan results in increased methylation of MID1IP1 gene
furan results in decreased expression of MID1IP1 mRNA

PMID:22079235 PMID:26194646

NCBI chr X:14,733,539...14,735,859
Ensembl chr X:14,732,830...14,739,079

G

mitochondrial elongation factor 1

increases methylation

EXP

furan results in increased methylation of MIEF1 gene

NCBI chr 7:113,666,918...113,679,550
Ensembl chr 7:113,666,901...113,683,977

G

MIER1 transcriptional regulator

increases methylation

EXP

furan results in increased methylation of MIER1 gene

NCBI chr 5:123,105,114...123,156,653
Ensembl chr 5:123,104,915...123,156,656

G

mitoguardin 2

increases methylation

EXP

furan results in increased methylation of MIGA2 gene

NCBI chr 3:34,034,018...34,056,703
Ensembl chr 3:34,034,044...34,056,703

G

migration and invasion inhibitory protein

increases methylation

EXP

furan results in increased methylation of MIIP gene

NCBI chr 5:163,575,689...163,582,739
Ensembl chr 5:163,575,437...163,582,873

G

microRNA 100

decreases expression

ISO

furan results in decreased expression of MIR100 mRNA

NCBI chr 8:50,798,295...50,798,374
Ensembl chr 8:50,798,295...50,798,374

G

microRNA 101-2

decreases expression

EXP

furan results in decreased expression of MIR101B mRNA

NCBI chr 1:236,273,922...236,274,018
Ensembl chr 1:236,273,922...236,274,018

G

microRNA 106b

increases expression

ISO

furan results in increased expression of MIR106B mRNA

NCBI chr12:22,157,053...22,157,134

G

microRNA 10a

decreases expression

ISO

furan results in decreased expression of MIR10A mRNA

NCBI chr10:81,779,709...81,779,818
Ensembl chr10:81,779,709...81,779,818

G

microRNA 122

decreases expression

EXP

furan results in decreased expression of MIR122 mRNA

PMID:22079235 PMID:27371368

NCBI chr18:61,028,817...61,028,901

G

microRNA 125a

decreases expression

ISO

furan results in decreased expression of MIR125A mRNA

NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759

G

microRNA 136

increases expression

EXP

furan results in increased expression of MIR136 mRNA

NCBI chr 6:134,331,335...134,331,416
Ensembl chr 6:134,331,335...134,331,416

G

microRNA 141

increases expression

EXP

furan results in increased expression of MIR141 mRNA

NCBI chr 4:159,209,525...159,209,618

G

microRNA 145

decreases expression

ISO

furan results in decreased expression of MIR145A mRNA

NCBI chr18:57,369,983...57,370,070

G

microRNA 146a

increases expression

EXP

furan results in increased expression of MIR146A mRNA

NCBI chr10:28,349,996...28,350,090

G

microRNA 146b

increases expression

EXP
ISO

furan results in increased expression of MIR146B mRNA

PMID:22079235 PMID:37517673

NCBI chr 1:255,144,860...255,144,947
Ensembl chr 1:255,144,860...255,144,947

G

microRNA 17

increases expression

ISO

furan results in increased expression of MIR17 mRNA

NCBI chr15:98,587,848...98,587,931
Ensembl chr15:98,587,848...98,587,931

G

microRNA 181c

decreases expression

EXP

furan results in decreased expression of MIR181C mRNA

NCBI chr19:40,888,291...40,888,396
Ensembl chr19:40,888,291...40,888,396

G

microRNA 183

increases expression
decreases expression

EXP
ISO

furan results in increased expression of MIR183 mRNA
furan results in decreased expression of MIR183 mRNA

PMID:22079235 PMID:37517673

NCBI chr 4:59,756,044...59,756,153

G

microRNA 184

increases expression

EXP

furan results in increased expression of MIR184 mRNA

NCBI chr 8:99,222,982...99,223,058

G

microRNA 187

decreases expression

EXP

furan results in decreased expression of MIR187 mRNA

NCBI chr18:16,005,947...16,006,050

G

microRNA 192

decreases expression

EXP
ISO

furan results in decreased expression of MIR192 mRNA

PMID:22079235 PMID:37517673

NCBI chr 1:212,994,209...212,994,318
Ensembl chr 1:212,994,209...212,994,318

G

microRNA 193a

decreases expression

EXP

furan results in decreased expression of MIR193A mRNA

NCBI chr10:65,170,306...65,170,417

G

microRNA 200a

increases expression
multiple interactions

EXP

furan results in increased expression of MIR200A mRNA
furan deficiency inhibits the reaction [furan results in increased expression of MIR200A mRNA]

PMID:22079235 PMID:27371368

NCBI chr 5:171,930,717...171,930,805

G

microRNA 200b

increases expression
multiple interactions

EXP

furan results in increased expression of MIR200B mRNA
furan deficiency inhibits the reaction [furan results in increased expression of MIR200B mRNA]

PMID:22079235 PMID:26194646 PMID:27371368

NCBI chr 5:171,931,495...171,931,589

G

microRNA 200c

increases expression

EXP

furan results in increased expression of MIR200C mRNA

NCBI chr 4:159,209,965...159,210,033

G

microRNA 203

decreases expression
increases expression

EXP
ISO

furan results in decreased expression of MIR203 mRNA
furan results in increased expression of MIR203B mRNA

PMID:22079235 PMID:37517673

NCBI chr 6:137,020,691...137,020,805

G

microRNA 204

increases expression

EXP

furan results in increased expression of MIR204 mRNA

NCBI chr 1:229,743,461...229,743,570
Ensembl chr 1:229,743,461...229,743,570

G

microRNA 207

decreases expression

EXP

furan results in decreased expression of MIR207 mRNA

NCBI chr 5:60,638,796...60,638,873
Ensembl chr 5:60,638,796...60,638,873

G

microRNA 20a

increases expression

ISO

furan results in increased expression of MIR20A mRNA

NCBI chr15:98,588,303...98,588,387
Ensembl chr15:98,588,303...98,588,387

G

microRNA 211

increases expression

EXP

furan results in increased expression of MIR211 mRNA

NCBI chr 1:127,189,328...127,189,433
Ensembl chr 1:127,189,328...127,189,433

G

microRNA 215

increases expression

EXP

furan results in increased expression of MIR215 mRNA

NCBI chr13:99,382,990...99,383,086

G

microRNA 22

decreases expression

EXP

furan results in decreased expression of MIR22 mRNA

NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425

G

microRNA 221

decreases expression

ISO

furan results in decreased expression of MIR221 mRNA

NCBI chr X:6,023,182...6,023,290
Ensembl chr X:6,023,182...6,023,290

G

microRNA 223

increases expression

EXP

furan results in increased expression of MIR223 mRNA

NCBI chr X:65,151,383...65,151,492
Ensembl chr X:65,151,383...65,151,492

G

microRNA 224

increases expression
multiple interactions

EXP

furan results in increased expression of MIR224 mRNA
furan deficiency inhibits the reaction [furan results in increased expression of MIR224 mRNA]

NCBI chr X:155,107,130...155,107,211

G

microRNA 26b

increases expression

EXP
ISO

furan results in increased expression of MIR26B mRNA

PMID:22079235 PMID:37517673

NCBI chr 9:83,425,709...83,425,793
Ensembl chr 9:83,425,709...83,425,793

G

microRNA 28

increases expression

EXP

furan results in increased expression of MIR28 mRNA

NCBI chr11:89,480,252...89,480,337

G

microRNA 296

decreases expression

EXP

furan results in decreased expression of MIR296 mRNA

NCBI chr 3:183,470,069...183,470,146

G

microRNA 298

decreases expression

EXP

furan results in decreased expression of MIR298 mRNA

NCBI chr 3:183,470,522...183,470,603

G

microRNA 30c-1

decreases expression

ISO

furan results in decreased expression of MIR30C-1 mRNA

NCBI chr 5:139,634,455...139,634,543

G

microRNA 324

increases expression

ISO

furan results in increased expression of MIR324 mRNA

NCBI chr10:55,233,363...55,233,445
Ensembl chr10:55,233,361...55,233,449

G

microRNA mir-335

decreases expression

EXP

furan results in decreased expression of MIR335 mRNA

G

microRNA 34a

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of MIR34A mRNA
furan deficiency inhibits the reaction [furan results in increased expression of MIR34A mRNA]

PMID:26194646 PMID:27371368 PMID:37517673

NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053

G

microRNA 375

multiple interactions
increases methylation
decreases expression

EXP

[furan results in increased methylation of MIR375 promoter] which results in decreased expression of MIR375 mRNA
furan results in decreased expression of MIR375 mRNA

NCBI chr 9:83,906,582...83,906,656

G

microRNA 376c

increases expression

EXP

furan results in increased expression of MIR376C mRNA

NCBI chr 6:134,558,205...134,558,288
Ensembl chr 6:134,558,205...134,558,288

G

microRNA 378

decreases expression

EXP

furan results in decreased expression of MIR378A mRNA

NCBI chr18:57,128,922...57,128,986

G

microRNA 379

increases expression

EXP

furan results in increased expression of MIR379 mRNA

NCBI chr 6:134,543,445...134,543,529
Ensembl chr 6:134,543,445...134,543,529

G

microRNA 429

increases expression

EXP

furan results in increased expression of MIR429 mRNA

NCBI chr 5:171,929,682...171,929,766

G

microRNA 448

decreases expression

EXP

furan results in decreased expression of MIR448 mRNA

NCBI chr X:115,641,955...115,642,066
Ensembl chr X:115,641,955...115,642,066

G

microRNA 451a

decreases expression

EXP

furan results in decreased expression of MIR451A mRNA

NCBI chr10:63,459,569...63,459,640
Ensembl chr10:63,459,569...63,459,640

G

microRNA 488

decreases expression

EXP

furan results in decreased expression of MIR488 mRNA

NCBI chr13:73,216,541...73,216,619
Ensembl chr13:73,216,541...73,216,619

G

microRNA 489

decreases expression

EXP

furan results in decreased expression of MIR489 mRNA

NCBI chr 4:32,648,039...32,648,144

G

microRNA 493

decreases expression

EXP

furan results in decreased expression of MIR493 mRNA

NCBI chr 6:134,314,731...134,314,814
Ensembl chr 6:134,314,731...134,314,814

G

microRNA 532

decreases expression

ISO

furan results in decreased expression of MIR532 mRNA

NCBI chr X:17,919,185...17,919,263
Ensembl chr X:17,919,185...17,919,263

G

microRNA 598

decreases expression

EXP

furan results in decreased expression of MIR598 mRNA

NCBI chr15:42,138,609...42,138,687
Ensembl chr15:42,138,609...42,138,688

G

microRNA 671

decreases expression

ISO

furan results in decreased expression of MIR671 mRNA

NCBI chr 4:11,473,194...11,473,274

G

microRNA 676

decreases expression

ISO

furan results in decreased expression of MIR676 mRNA

NCBI chr X:69,504,596...69,504,684
Ensembl chr X:69,504,596...69,504,684

G

microRNA 93

increases expression
multiple interactions

EXP

furan results in increased expression of MIR93 mRNA
furan deficiency inhibits the reaction [furan results in increased expression of MIR93 mRNA]

NCBI chr12:22,156,844...22,156,930

G

microRNA 96

decreases expression

ISO

furan results in decreased expression of MIR96 mRNA

NCBI chr 4:59,755,841...59,755,946

G

microRNA 99a

decreases expression

ISO

furan results in decreased expression of MIR99A mRNA

NCBI chr11:29,687,392...29,687,472
Ensembl chr11:29,687,392...29,687,472

G

microRNA 99b

decreases expression

ISO

furan results in decreased expression of MIR99B mRNA

NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:67,350,060...67,350,139

G

microRNA let-7e

decreases expression

EXP

furan results in decreased expression of MIRLET7E mRNA

NCBI chr 1:67,350,229...67,350,321

G

MIS18 kinetochore protein A

increases expression

EXP

furan results in increased expression of MIS18A mRNA

NCBI chr11:43,454,129...43,467,157
Ensembl chr11:43,454,161...43,476,264

G

MIS18 binding protein 1

increases expression

EXP

furan results in increased expression of MIS18BP1 mRNA

NCBI chr 6:88,918,743...88,968,225
Ensembl chr 6:88,918,745...88,967,629

G

marker of proliferation Ki-67

increases expression

EXP

furan results in increased expression of MKI67 mRNA; furan results in increased expression of MKI67 protein

PMID:20562052 PMID:22507866 PMID:25539665

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

MAPK interacting serine/threonine kinase 2

increases expression

EXP

furan results in increased expression of MKNK2 mRNA

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

modulator of VRAC current 1

increases methylation

EXP

furan results in increased methylation of MLC1 gene

NCBI chr 7:121,926,356...121,949,484
Ensembl chr 7:121,926,356...121,946,698

G

malectin

increases expression

EXP

furan results in increased expression of MLEC mRNA

NCBI chr12:47,118,918...47,133,598
Ensembl chr12:47,118,855...47,130,064

G

mutL homolog 3

decreases expression

EXP

furan results in decreased expression of MLH3 mRNA

NCBI chr 6:110,612,535...110,649,408
Ensembl chr 6:110,612,535...110,648,999

G

motilin receptor

increases methylation

EXP

furan results in increased methylation of TRHR2 gene

NCBI chr19:67,317,269...67,340,508
Ensembl chr19:67,322,133...67,327,323

G

MLX interacting protein-like

decreases expression

EXP

furan results in decreased expression of MLXIPL mRNA

NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660

G

monocyte to macrophage differentiation-associated

increases expression

EXP

furan results in increased expression of MMD mRNA

NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609

G

monocyte to macrophage differentiation-associated 2

decreases expression

EXP

furan results in decreased expression of MMD2 mRNA

NCBI chr12:17,075,870...17,123,255
Ensembl chr12:17,076,260...17,123,904

G

membrane metallo-endopeptidase-like 1

decreases expression

EXP

furan results in decreased expression of MMEL1 mRNA

NCBI chr 5:170,713,602...170,744,058
Ensembl chr 5:170,713,627...170,744,058

G

matrix metallopeptidase 11

increases expression

EXP

furan results in increased expression of MMP11 mRNA

NCBI chr20:12,730,284...12,739,067
Ensembl chr20:12,730,277...12,739,290

G

matrix metallopeptidase 12

increases expression

EXP

furan results in increased expression of MMP12 mRNA

PMID:26194646 PMID:27387713

NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478

G

matrix metallopeptidase 13

increases expression

EXP

furan results in increased expression of MMP13 mRNA

NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105

G

matrix metallopeptidase 14

increases methylation

EXP

furan results in increased methylation of MMP14 gene

NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893

G

matrix metallopeptidase 2

increases expression

EXP

furan results in increased expression of MMP2 mRNA

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 23

increases methylation
increases expression

EXP

furan results in increased methylation of MMP23 gene
furan results in increased expression of MMP23 mRNA

PMID:22079235 PMID:27387713

NCBI chr 5:171,521,905...171,525,007
Ensembl chr 5:171,520,494...171,524,695

G

matrix metallopeptidase 7

increases expression

EXP

furan results in increased expression of MMP7 mRNA

PMID:26194646 PMID:27387713

NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755

G

multimerin 2

increases methylation

EXP

furan results in increased methylation of MMRN2 gene

NCBI chr16:9,712,181...9,733,653
Ensembl chr16:9,711,953...9,733,653

G

MMS22-like, DNA repair protein

increases expression

EXP

furan results in increased expression of MMS22L mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:42,994,382...43,110,371
Ensembl chr 5:42,994,359...43,110,369

G

methylmalonyl-CoA mutase

decreases expression

EXP

furan results in decreased expression of MMUT mRNA

NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342

G

myeloid cell nuclear differentiation antigen

increases expression

EXP

furan results in increased expression of IFI204 mRNA

NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537

G

meiosis-specific nuclear structural 1

increases expression

EXP

furan results in increased expression of MNS1 mRNA

NCBI chr 8:82,029,587...82,050,276
Ensembl chr 8:82,029,587...82,050,274

G

MOB kinase activator 3B

increases expression

ISO

furan results in increased expression of MOB3B mRNA

NCBI chr 5:54,342,509...54,534,164
Ensembl chr 5:54,338,056...54,454,678

G

monoacylglycerol O-acyltransferase 1

increases expression

EXP

furan results in increased expression of MOGAT1 mRNA

NCBI chr 9:87,429,427...87,436,977
Ensembl chr 9:87,405,119...87,436,977

G

monoacylglycerol O-acyltransferase 2

increases expression
multiple interactions

ISO
EXP

furan results in increased expression of MOGAT2 mRNA
[Bromodeoxyuridine co-treated with furan] affects the expression of MOGAT2 mRNA

PMID:24183702 PMID:24910943 PMID:25539665 PMID:26194646

NCBI chr 1:162,933,964...162,957,896
Ensembl chr 1:162,933,966...162,957,896

G

MON1 homolog B, secretory trafficking associated

decreases expression

EXP

furan results in decreased expression of MON1B mRNA

NCBI chr19:58,526,503...58,534,478
Ensembl chr19:58,526,326...58,533,950

G

mortality factor 4 like 2

increases expression

ISO

furan results in increased expression of MORF4L2 mRNA

NCBI chr X:104,874,850...104,885,946
Ensembl chr X:104,852,693...104,892,855

G

MORN repeat containing 1

increases methylation
increases expression
decreases expression

EXP
ISO

furan results in increased methylation of MORN1 gene
furan results in increased expression of MORN1 mRNA
furan results in decreased expression of MORN1 mRNA

PMID:22079235 PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr 5:170,928,086...170,987,219
Ensembl chr 5:170,929,321...170,987,218

G

MORN repeat containing 4

increases expression

EXP

furan results in increased expression of MORN4 mRNA

NCBI chr 1:250,837,639...250,847,943
Ensembl chr 1:250,837,643...250,848,026

G

MORN repeat containing 5

increases expression

EXP

furan results in increased expression of MORN5 mRNA

NCBI chr 3:39,799,531...39,827,482
Ensembl chr 3:39,799,019...39,827,482

G

macrophage expressed 1

decreases expression

EXP

furan results in decreased expression of MPEG1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:218,876,848...218,881,364
Ensembl chr 1:218,876,069...218,908,715

G

N-methylpurine-DNA glycosylase

decreases expression

EXP

furan results in decreased expression of MPG mRNA

NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052

G

myeloperoxidase

increases activity
multiple interactions

EXP

furan results in increased activity of MPO protein
protocatechuic acid inhibits the reaction [furan results in increased activity of MPO protein]

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

myosin phosphatase Rho interacting protein

increases methylation

EXP

furan results in increased methylation of MPRIP gene

NCBI chr10:44,953,472...45,073,388
Ensembl chr10:44,953,500...45,073,388

G

mercaptopyruvate sulfurtransferase

affects binding
increases expression

EXP

furan binds to MPST protein
furan results in increased expression of MPST mRNA

PMID:22240984 PMID:26194646

NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650

G

myelin protein zero-like 1

increases expression

EXP

furan results in increased expression of MPZL1 mRNA

NCBI chr13:80,385,454...80,422,315
Ensembl chr13:80,385,456...80,422,390

G

myelin protein zero-like 2

increases expression

EXP

furan results in increased expression of MPZL2 mRNA

PMID:25539665 PMID:27387713

NCBI chr 8:54,244,920...54,256,064
Ensembl chr 8:54,243,556...54,256,074

G

myelin protein zero-like 3

increases expression

EXP

furan results in increased expression of MPZL3 mRNA

NCBI chr 8:54,257,235...54,277,422
Ensembl chr 8:54,257,226...54,279,665

G

muscle RAS oncogene homolog

decreases expression

EXP

furan results in decreased expression of MRAS mRNA

NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911

G

mannose receptor, C type 1

increases methylation

EXP

furan results in increased methylation of MRC1 gene

NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410

G

mannose receptor, C type 2

increases expression

EXP

furan results in increased expression of MRC2 mRNA

NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055

G

melanoregulin

decreases expression

EXP

furan results in decreased expression of MREG mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:81,236,019...81,291,601
Ensembl chr 9:81,236,019...81,291,310

G

Morf4 family associated protein 1

increases methylation

EXP

furan results in increased methylation of MRFAP1 gene

NCBI chr14:78,227,225...78,229,002

G

MAS-related GPR, member B13

affects methylation

EXP

furan affects the methylation of MRGPRB13 gene

NCBI chr 1:107,177,257...107,178,243
Ensembl chr 1:107,177,257...107,178,243

G

MAS related GPR family member G

decreases expression

EXP

furan results in decreased expression of MRGPRG mRNA

NCBI chr 1:208,377,008...208,380,916
Ensembl chr 1:208,375,669...208,380,984

G

MAS related GPR family member X3

decreases methylation
increases expression

EXP

furan results in decreased methylation of MRGPRX3 gene
furan results in increased expression of MRGPRX3 mRNA

PMID:22079235 PMID:27387713

NCBI chr 1:106,857,685...106,883,199
Ensembl chr 1:106,857,687...106,883,145

G

mitochondrial rRNA methyltransferase 1

increases methylation

EXP

furan results in increased methylation of MRM1 gene

NCBI chr10:70,187,842...70,194,785
Ensembl chr10:70,188,748...70,194,131

G

mitochondrial ribosomal protein L14

decreases expression

EXP

furan results in decreased expression of MRPL14 mRNA

NCBI chr 9:22,800,286...22,812,711
Ensembl chr 9:22,795,744...22,812,855

G

mitochondrial ribosomal protein L17

increases expression

EXP

furan results in increased expression of MRPL17 mRNA

NCBI chr 1:169,574,010...169,575,699
Ensembl chr 1:169,574,010...169,575,818

G

mitochondrial ribosomal protein L43

increases methylation

EXP

furan results in increased methylation of MRPL43 gene

NCBI chr 1:253,816,009...253,817,441
Ensembl chr 1:253,816,009...253,817,441

G

mitochondrial ribosomal protein L46

increases methylation

EXP

furan results in increased methylation of MRPL46 gene

NCBI chr 1:142,108,266...142,117,030
Ensembl chr 1:142,106,531...142,117,030

G

mitochondrial ribosomal protein L9

decreases methylation

EXP

furan results in decreased methylation of MRPL9 gene

NCBI chr 2:184,768,837...184,775,787
Ensembl chr 2:184,763,529...184,775,777

G

mitochondrial ribosomal protein S10

decreases expression

EXP

furan results in decreased expression of MRPS10 mRNA

NCBI chr 9:21,112,549...21,122,461
Ensembl chr 9:21,112,549...21,122,453

G

mitochondrial ribosomal protein S18A

increases methylation

EXP

furan results in increased methylation of MRPS18A gene

NCBI chr 9:22,350,887...22,367,380
Ensembl chr 9:22,344,341...22,367,380

G

mitochondrial ribosomal protein S34

increases methylation

EXP

furan results in increased methylation of MRPS34 gene

NCBI chr10:14,420,543...14,421,674
Ensembl chr10:14,408,136...14,421,771

G

membrane spanning 4-domains A10

increases expression

EXP

furan results in increased expression of MS4A10 mRNA

NCBI chr 1:217,034,156...217,049,369
Ensembl chr 1:217,036,206...217,049,346

G

membrane spanning 4-domains A2

increases expression

EXP

furan results in increased expression of MS4A2 mRNA

NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:217,865,159...217,873,108

G

membrane spanning 4-domains A7

increases expression

EXP

furan results in increased expression of MS4A7 mRNA

NCBI chr 1:217,394,019...217,409,643
Ensembl chr 1:217,394,019...217,409,643

G

membrane spanning 4-domains A8

increases expression

EXP

furan results in increased expression of MS4A8A mRNA

NCBI chr 1:217,155,557...217,169,151
Ensembl chr 1:217,155,557...217,169,215

G

Myb/SANT DNA binding domain containing 3

increases expression

EXP

furan results in increased expression of MSANTD3 mRNA

NCBI chr 5:67,661,551...67,687,971
Ensembl chr 5:67,661,912...67,684,384

G

mutS homolog 2

increases expression

EXP

furan results in increased expression of MSH2 mRNA

NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503

G

mesothelin

increases expression

EXP

furan results in increased expression of MSLN mRNA

NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153

G

methylsterol monooxygenase 1

decreases expression

EXP

furan results in decreased expression of MSMO1 mRNA

NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445

G

macrophage stimulating 1

increases methylation
decreases expression

EXP

furan results in increased methylation of MST1 gene
furan results in decreased expression of MST1 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 8:117,646,485...117,652,016
Ensembl chr 8:117,647,438...117,652,015

G

msh homeobox 1

decreases expression

EXP

furan results in decreased expression of MSX1 mRNA

NCBI chr14:77,185,802...77,189,735
Ensembl chr14:77,185,802...77,189,735

G

msh homeobox 2

decreases expression

EXP

furan results in decreased expression of MSX2 mRNA

NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945

G

metallothionein 1A

decreases expression
increases expression

EXP

furan results in decreased expression of MT1A mRNA
furan results in increased expression of MT1A mRNA

PMID:15120968 PMID:26194646

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 2

increases expression

EXP

furan results in increased expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

metallothionein 4

decreases expression

EXP

furan results in decreased expression of MT4 mRNA

NCBI chr19:10,869,735...10,871,831
Ensembl chr19:10,869,735...10,871,831

G

mitochondrial carrier 1

increases methylation

EXP

furan results in increased methylation of MTCH1 gene

NCBI chr20:7,391,558...7,415,291
Ensembl chr20:7,391,565...7,415,042

G

mitochondrial transcription termination factor 1

decreases methylation

EXP

furan results in decreased methylation of MTERF1 gene

NCBI chr 4:31,181,048...31,188,130
Ensembl chr 4:31,180,832...31,189,651

G

methenyltetrahydrofolate synthetase

increases methylation

EXP

furan results in increased methylation of MTHFS gene

NCBI chr 8:98,609,410...98,681,901
Ensembl chr 8:98,609,399...98,752,036

G

mitochondrial translational initiation factor 3

decreases expression

ISO

furan results in decreased expression of MTIF3 mRNA

NCBI chr12:13,240,091...13,251,350
Ensembl chr12:13,240,173...13,254,373

G

myotubularin related protein 7

decreases expression

EXP

furan results in decreased expression of MTMR7 mRNA

NCBI chr16:58,344,755...58,435,682
Ensembl chr16:58,344,767...58,436,615

G

melatonin receptor 1A

increases expression

ISO

furan results in increased expression of MTNR1A mRNA

NCBI chr16:53,876,964...53,896,421
Ensembl chr16:53,876,964...53,896,421

G

mitochondrial translation release factor 1 like

increases methylation

EXP

furan results in increased methylation of MTRF1L gene

NCBI chr 1:44,614,162...44,626,367
Ensembl chr 1:44,615,921...44,626,178

G

MTSS I-BAR domain containing 1

increases expression

EXP

furan results in increased expression of MTSS1 mRNA

NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303

G

microsomal triglyceride transfer protein

increases methylation

EXP

furan results in increased methylation of MTTP gene

NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650

G

microtubule associated scaffold protein 1

increases methylation

EXP

furan results in increased methylation of MTUS1 gene

NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474

G

mucin 1, cell surface associated

increases expression

EXP

furan results in increased expression of MUC1 mRNA

NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491

G

mucin 2, oligomeric mucus/gel-forming

decreases expression

EXP

furan results in decreased expression of MUC2 mRNA

NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280

G

murinoglobulin 1

decreases expression

EXP

furan results in decreased expression of MUG1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:156,748,351...156,802,132

G

murinoglobulin 2

decreases expression

EXP

furan results in decreased expression of MUG2 mRNA; furan results in decreased expression of PZP mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:156,836,140...156,908,972

G

murinoglobulin 6

decreases expression

EXP

furan results in decreased expression of CPAMD8 mRNA

NCBI chr 4:157,004,905...157,085,187
Ensembl chr 4:157,004,905...157,085,250

G

major urinary protein 4

decreases expression

EXP

furan results in decreased expression of MUP4 mRNA

NCBI chr 5:79,756,142...79,759,496

G

major urinary protein 5

decreases expression

EXP

furan results in decreased expression of MUP5 mRNA

NCBI chr 5:79,996,023...79,999,893

G

mutY DNA glycosylase

increases expression

EXP

furan results in increased expression of MUTYH mRNA

NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:135,517,695...135,522,776

G

max dimerization protein 1

increases expression

EXP

furan results in increased expression of MXD1 mRNA

NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129

G

Max dimerization protein 3

increases expression

EXP

furan results in increased expression of MXD3 mRNA

NCBI chr17:9,306,552...9,310,278
Ensembl chr17:9,302,321...9,310,278

G

matrix remodeling associated 8

increases expression

EXP

furan results in increased expression of MXRA8 mRNA

NCBI chr 5:171,731,153...171,735,879
Ensembl chr 5:171,731,353...171,735,879

G

myeloid-associated differentiation marker

increases expression

EXP

furan results in increased expression of MYADM mRNA

NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710

G

MYB proto-oncogene like 1

increases expression
decreases expression
increases methylation

EXP

furan results in increased expression of MYBL1 mRNA
furan results in decreased expression of MYBL1 mRNA
furan results in increased methylation of MYBL1 gene

PMID:25539665 PMID:27387713

NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588

G

MYB proto-oncogene like 2

increases expression
decreases expression

EXP

furan results in increased expression of MYBL2 mRNA
furan results in decreased expression of MYBL2 mRNA

PMID:25539665 PMID:27387713

NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221

G

myosin binding protein H-like

increases methylation
decreases expression

EXP

furan results in increased methylation of MYBPHL gene
furan results in decreased expression of MYBPHL mRNA

PMID:22079235 PMID:25539665

NCBI chr 2:198,692,857...198,706,953
Ensembl chr 2:198,693,101...198,705,738

G

MYC proto-oncogene, bHLH transcription factor

increases expression
decreases expression
multiple interactions

EXP
ISO

furan results in increased expression of MYC mRNA
furan results in decreased expression of MYC mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of MYC mRNA

PMID:20124500 PMID:24183702 PMID:24910943 PMID:25539665 PMID:37517673

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

MYCN proto-oncogene, bHLH transcription factor

increases methylation

EXP

furan results in increased methylation of MYCN gene

NCBI chr 6:41,446,683...41,452,584
Ensembl chr 6:41,446,684...41,452,508

G

myosin heavy chain 1

increases expression

EXP

furan results in increased expression of MYH1 mRNA

NCBI chr10:52,384,810...52,408,698
Ensembl chr10:52,384,908...52,409,047

G

myosin heavy chain 10

increases expression
decreases methylation

EXP

furan results in increased expression of MYH10 mRNA
furan results in decreased methylation of MYH10 gene

PMID:25539665 PMID:27387713

NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036

G

myosin heavy chain 7B

increases expression

EXP

furan results in increased expression of MYH7B mRNA

NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:164,558,340...164,582,094

G

myosin light chain 9

increases methylation

EXP

furan results in increased methylation of MYL9 gene

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410

G

myosin regulatory light chain interacting protein

increases expression

EXP

furan results in increased expression of MYLIP mRNA

NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,492,826...19,514,471

G

myosin light chain kinase

decreases expression

EXP

furan results in decreased expression of MYLK mRNA

NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659

G

myosin VIIb

increases expression

EXP

furan results in increased expression of MYO7B mRNA

NCBI chr18:23,862,533...23,944,081
Ensembl chr18:23,862,533...23,944,049

G

myosin IXA

increases methylation

EXP

furan results in increased methylation of MYO9A gene

NCBI chr 8:69,044,853...69,248,094
Ensembl chr 8:69,044,885...69,245,231

G

myocilin

increases expression

EXP

furan results in increased expression of MYOC mRNA

NCBI chr13:77,509,963...77,520,361
Ensembl chr13:77,509,963...77,520,361

G

myocardin

increases methylation

EXP

furan results in increased methylation of MYOCD gene

NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819

G

myoferlin

increases expression

EXP

furan results in increased expression of MYOF mRNA

NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768

G

myogenesis regulating glycosidase

increases methylation

EXP

furan results in increased methylation of MYORG gene

NCBI chr 5:61,452,956...61,460,500
Ensembl chr 5:61,432,418...61,460,581

G

myozenin 1

increases methylation
increases expression

EXP

furan results in increased methylation of MYOZ1 gene
furan results in increased expression of MYOZ1 mRNA

PMID:22079235 PMID:27387713

NCBI chr15:3,693,576...3,700,831
Ensembl chr15:3,693,613...3,700,826

G

myocardial zonula adherens protein

increases expression

EXP

furan results in increased expression of GCOM1 mRNA

NCBI chr 8:81,036,599...81,123,933
Ensembl chr 8:81,036,601...81,123,810

G

myeloid zinc finger 1

decreases expression

EXP

furan results in decreased expression of MZF1 mRNA

NCBI chr 1:82,742,709...82,755,069
Ensembl chr 1:82,742,726...82,753,820

G

N(alpha)-acetyltransferase 60, NatF catalytic subunit

increases methylation

EXP

furan results in increased methylation of NAA60 gene

NCBI chr10:12,129,026...12,149,053
Ensembl chr10:12,131,429...12,139,262

G

N-acylethanolamine acid amidase

increases methylation
decreases methylation
increases expression

EXP

furan results in increased methylation of NAAA gene
furan results in decreased methylation of NAAA gene
furan results in increased expression of NAAA mRNA

PMID:22079235 PMID:27387713

NCBI chr14:16,061,599...16,080,703
Ensembl chr14:16,061,583...16,080,702

G

N-acetylated alpha-linked acidic dipeptidase-like 1

increases expression

EXP

furan results in increased expression of NAALADL1 mRNA

NCBI chr 1:212,829,917...212,843,474
Ensembl chr 1:212,829,916...212,843,474

G

N-acetylated alpha-linked acidic dipeptidase-like 2

decreases expression

EXP

furan results in decreased expression of NAALADL2 mRNA

NCBI chr 2:108,568,000...109,920,650
Ensembl chr 2:108,573,985...109,920,756

G

NAC alpha domain containing

increases expression

EXP

furan results in increased expression of NACAD mRNA

NCBI chr14:85,679,215...85,688,742
Ensembl chr14:85,679,215...85,688,147

G

NALCN channel auxiliary factor 2

decreases expression

EXP

furan results in decreased expression of NALF2 mRNA

NCBI chr X:68,965,327...68,991,201
Ensembl chr X:68,965,327...68,991,201

G

nicotinamide phosphoribosyltransferase

decreases expression

EXP

furan results in decreased expression of NAMPT mRNA

NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544

G

Nanog homeobox

decreases expression

EXP

furan results in decreased expression of NANOG mRNA

NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061

G

N-acetyltransferase 14

increases methylation

EXP

furan results in increased methylation of NAT14 gene

NCBI chr 1:77,939,430...77,941,950

G

N-acetyltransferase 8

increases methylation
increases expression

EXP

furan results in increased methylation of NAT8 gene
furan results in increased expression of NAT8 mRNA

PMID:22079235 PMID:25539665

NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159

G

N-acetyltransferase 8 (GCN5-related) family member 2

decreases expression
increases expression

EXP

furan results in decreased expression of NAT8F2 mRNA
furan results in increased expression of NAT8F2 mRNA

NCBI chr 4:119,877,449...119,880,685
Ensembl chr 4:119,877,465...119,890,291

G

N-acetyltransferase 8 (GCN5-related) family member 5

increases expression

ISO
EXP

furan results in increased expression of NAT8F5 mRNA

PMID:24183702 PMID:25539665

NCBI chr 4:119,817,788...119,842,503
Ensembl chr 4:119,816,735...119,863,953

G

NBL1, DAN family BMP antagonist

increases expression

EXP

furan results in increased expression of NBL1 mRNA

NCBI chr 5:156,601,986...156,613,182
Ensembl chr 5:156,601,986...156,613,186

G

neural cell adhesion molecule 1

increases expression

EXP

furan results in increased expression of NCAM1 mRNA

NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:58,762,116...59,061,971

G

neural cell adhesion molecule 2

increases methylation
decreases expression

EXP

furan results in increased methylation of NCAM2 gene
furan results in decreased expression of NCAM2 mRNA

PMID:22079235 PMID:25539665

NCBI chr11:33,591,748...34,078,788
Ensembl chr11:33,591,713...34,078,788

G

non-SMC condensin I complex, subunit G

increases expression

EXP

furan results in increased expression of NCAPG mRNA

NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445

G

non-SMC condensin I complex, subunit H

increases expression

EXP

furan results in increased expression of NCAPH mRNA

NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502

G

neutral cholesterol ester hydrolase 1

decreases expression

EXP

furan results in decreased expression of NCEH1 mRNA

NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:112,003,502...112,064,272

G

NCK adaptor protein 2

increases methylation

EXP

furan results in increased methylation of NCK2 gene

NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:53,231,381...53,332,394

G

NCK associated protein 1 like

decreases methylation

EXP

furan results in decreased methylation of NCKAP1L gene

NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384

G

nuclear receptor coactivator 2

increases methylation

EXP

furan results in increased methylation of NCOA2 gene

NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776

G

nuclear receptor coactivator 4

increases methylation

EXP

furan results in increased methylation of NCOA4 gene

NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840

G

NDC1 transmembrane nucleoporin

increases expression

EXP

furan results in increased expression of NDC1 mRNA

NCBI chr 5:127,384,172...127,431,093
Ensembl chr 5:127,384,665...127,431,090

G

NDC80 kinetochore complex component

increases expression

EXP

furan results in increased expression of NDC80 mRNA

NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568

G

N-myc downstream regulated 1

increases expression

EXP

furan results in increased expression of NDRG1 mRNA

NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913

G

NDRG family member 2

affects binding
decreases expression

EXP

furan binds to NDRG2 protein
furan results in decreased expression of NDRG2 mRNA

PMID:22240984 PMID:26194646

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

NADH:ubiquinone oxidoreductase subunit A12

increases methylation

EXP

furan results in increased methylation of NDUFA12 gene

NCBI chr 7:30,658,316...30,685,302
Ensembl chr 7:30,658,322...30,686,300

G

NADH:ubiquinone oxidoreductase subunit A6

decreases expression

EXP

furan results in decreased expression of NDUFA6 mRNA

NCBI chr 7:115,746,460...115,750,317
Ensembl chr 7:115,746,460...115,750,317

G

NADH:ubiquinone oxidoreductase subunit B2

decreases expression

EXP

furan results in decreased expression of NDUFB2 mRNA

NCBI chr 4:69,334,307...69,341,394
Ensembl chr 4:69,334,307...69,340,136
Ensembl chr15:69,334,307...69,340,136

G

NADH:ubiquinone oxidoreductase subunit B4

increases methylation

EXP

furan results in increased methylation of NDUFB4 gene

NCBI chr11:76,569,178...76,575,879
Ensembl chr11:76,569,178...76,575,879

G

NADH:ubiquinone oxidoreductase core subunit V2

increases methylation

EXP

furan results in increased methylation of NDUFV2 gene

NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520

G

nuclear paraspeckle assembly transcript 1

decreases expression

ISO

furan results in decreased expression of NEAT1 mRNA

NCBI chr 1:212,507,512...212,568,055

G

nectin cell adhesion molecule 4

increases expression

EXP

furan results in increased expression of NECTIN4 mRNA

NCBI chr13:86,335,027...86,354,152
Ensembl chr13:86,335,831...86,353,967

G

neurofilament light chain

increases expression

EXP

furan results in increased expression of NEFL mRNA

NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515

G

nei-like DNA glycosylase 2

increases expression

EXP

furan results in increased expression of NEIL2 mRNA

NCBI chr15:41,620,650...41,631,551
Ensembl chr15:41,621,352...41,630,834

G

NIMA-related kinase 2

increases expression

EXP

furan results in increased expression of NEK2 mRNA

PMID:22079235 PMID:25539665

NCBI chr13:105,936,809...105,950,054
Ensembl chr13:105,936,788...105,950,056

G

NIMA-related kinase 5

increases expression

EXP

furan results in increased expression of NEK5 mRNA

NCBI chr16:76,597,857...76,641,113
Ensembl chr16:76,597,747...76,641,832

G

nestin

decreases expression
increases expression

EXP

furan results in decreased expression of NES mRNA
furan results in increased expression of NES mRNA

PMID:25539665 PMID:27387713

NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228

G

neuroepithelial cell transforming 1

decreases expression

EXP

furan results in decreased expression of NET1 mRNA

NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270

G

neuraminidase 2

increases expression

EXP

furan results in increased expression of NEU2 mRNA

NCBI chr 9:95,666,338...95,715,209
Ensembl chr 9:95,696,507...95,715,208

G

neuralized E3 ubiquitin protein ligase 1

decreases expression

EXP

furan results in decreased expression of NEURL1 mRNA

NCBI chr 1:256,008,012...256,094,219
Ensembl chr 1:256,008,160...256,094,224

G

nexilin (F actin binding protein)

increases expression

EXP

furan results in increased expression of NEXN mRNA

NCBI chr 2:243,846,736...243,878,268
Ensembl chr 2:243,846,433...243,887,114

G

NFE2 like bZIP transcription factor 2

increases activity

ISO

furan results in increased activity of NFE2L2 protein

NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090

G

nuclear factor I/A

increases methylation

EXP

furan results in increased methylation of NFIA gene

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395

G

nuclear factor I/C

decreases expression

EXP

furan results in decreased expression of NFIC mRNA

NCBI chr 7:8,928,423...8,963,455
Ensembl chr 7:8,904,117...8,963,409

G

nuclear factor, interleukin 3 regulated

decreases expression

EXP

furan results in decreased expression of NFIL3 mRNA

PMID:25539665 PMID:26194646

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826

G

NFKB inhibitor alpha

increases expression
increases phosphorylation
multiple interactions
decreases expression

EXP
ISO

furan results in increased expression of NFKBIA mRNA
furan results in increased phosphorylation of NFKBIA protein
rhodioloside inhibits the reaction [furan results in increased phosphorylation of NFKBIA protein]
furan results in decreased expression of NFKBIA mRNA

PMID:15120968 PMID:20194422 PMID:26194646 PMID:34450210

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

NFKB inhibitor zeta

decreases expression

EXP

furan results in decreased expression of NFKBIZ mRNA

NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767

G

nerve growth factor receptor

multiple interactions
increases expression

ISO

[Bromodeoxyuridine co-treated with furan] results in increased expression of TNFRSF10B mRNA
furan results in increased expression of TNFRSF10B mRNA

PMID:24183702 PMID:24910943 PMID:37517673

NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305

G

NHERF family PDZ scaffold protein 1

affects binding

EXP

furan binds to NHERF1 protein

NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579

G

NHP2 ribonucleoprotein

increases expression

EXP

furan results in increased expression of NHP2 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354

G

niban apoptosis regulator 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of NIBAN2 gene
furan results in increased expression of NIBAN2 mRNA

NCBI chr 3:36,572,356...36,621,968
Ensembl chr 3:36,572,377...36,621,967

G

nidogen 2

increases expression

EXP

furan results in increased expression of NID2 mRNA

NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949

G

NIM1 serine/threonine protein kinase

decreases expression

EXP

furan results in decreased expression of NIM1K mRNA

NCBI chr 2:53,403,467...53,451,248
Ensembl chr 2:53,403,473...53,419,656

G

ninjurin 2

increases expression

EXP

furan results in increased expression of NINJ2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:154,978,660...155,080,860
Ensembl chr 4:155,073,295...155,080,860

G

NIPA-like domain containing 2

increases expression

EXP

furan results in increased expression of NIPAL2 mRNA

PMID:25539665 PMID:27387713

NCBI chr 7:67,659,628...67,771,105
Ensembl chr 7:67,659,628...67,769,959

G

Sodium/potassium transporting ATPase interacting 1

increases expression

EXP

furan results in increased expression of NKAIN1 mRNA

NCBI chr 5:148,031,685...148,076,834
Ensembl chr 5:148,031,338...148,076,834

G

NFKB activating protein

increases methylation

EXP

furan results in increased methylation of NKAP gene

NCBI chr X:121,238,714...121,258,360
Ensembl chr X:121,238,404...121,261,238

G

NK1 homeobox 2

decreases expression

EXP

furan results in decreased expression of NKX1-2 mRNA

NCBI chr 1:196,816,491...196,821,371
Ensembl chr 1:196,816,491...196,821,371

G

notchless homolog 1

increases methylation

EXP

furan results in increased methylation of NLE1 gene

NCBI chr10:68,331,609...68,342,562
Ensembl chr10:68,331,609...68,340,386

G

NLR family, pyrin domain containing 3

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of NLRP3 mRNA
rhodioloside inhibits the reaction [furan results in increased expression of NLRP3 protein]

PMID:27387713 PMID:34450210

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

neuromedin B receptor

increases methylation

EXP

furan results in increased methylation of NMBR gene

NCBI chr 1:10,942,476...10,966,174
Ensembl chr 1:10,954,916...10,965,555

G

NME/NM23 nucleoside diphosphate kinase 3

increases methylation
decreases expression

EXP

furan results in increased methylation of NME3 gene
furan results in decreased expression of NME3 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr10:14,421,922...14,422,878
Ensembl chr10:14,421,702...14,422,907

G

NME/NM23 nucleoside diphosphate kinase 4

increases expression
decreases methylation

EXP

furan results in increased expression of NME4 mRNA
furan results in decreased methylation of NME4 gene

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr10:15,619,106...15,622,961
Ensembl chr10:15,619,106...15,623,098

G

nicotinamide nucleotide adenylyltransferase 3

decreases expression

EXP

furan results in decreased expression of NMNAT3 mRNA

NCBI chr 8:107,771,124...107,888,528
Ensembl chr 8:107,771,509...107,900,016

G

nicotinamide riboside kinase 1

increases expression

EXP

furan results in increased expression of NMRK1 mRNA

NCBI chr 1:225,475,975...225,503,414
Ensembl chr 1:225,475,830...225,503,602

G

N-myristoyltransferase 2

increases expression

EXP

furan results in increased expression of NMT2 mRNA

NCBI chr17:79,826,999...79,874,088
Ensembl chr17:79,826,999...79,870,259

G

neuromedin U

increases expression

EXP

furan results in increased expression of NMU mRNA

NCBI chr14:32,198,789...32,226,397
Ensembl chr14:32,198,943...32,226,632

G

neuronatin

increases methylation
increases expression

EXP

furan results in increased methylation of NNAT gene
furan results in increased expression of NNAT mRNA

PMID:22079235 PMID:27387713

NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086

G

nicotinamide N-methyltransferase

increases methylation

EXP

furan results in increased methylation of NNMT gene

NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174

G

noggin

decreases expression

EXP

furan results in decreased expression of NOG mRNA

NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103

G

nucleolar protein 3

increases expression

EXP

furan results in increased expression of NOL3 mRNA

PMID:20562052 PMID:22079235 PMID:25539665 PMID:27387713

NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722

G

nucleolar protein 8

increases expression

EXP

furan results in increased expression of NOL8 mRNA

NCBI chr17:15,196,881...15,220,265
Ensembl chr17:15,196,881...15,220,202

G

NOP16 nucleolar protein

increases methylation

EXP

furan results in increased methylation of NOP16 gene

NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038

G

NOP58 ribonucleoprotein

increases expression

ISO

furan results in increased expression of NOP58 mRNA

NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909

G

nitric oxide synthase 1 adaptor protein

decreases expression

EXP

furan results in decreased expression of NOS1AP mRNA

NCBI chr13:85,080,558...85,353,741
Ensembl chr13:85,063,350...85,353,741

G

notch receptor 1

decreases expression

EXP

furan results in decreased expression of NOTCH1 mRNA

NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613

G

notch receptor 4

increases expression

EXP

furan results in increased expression of NOTCH4 mRNA

NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072

G

NOTUM, palmitoleoyl-protein carboxylesterase

decreases expression

EXP

furan results in decreased expression of NOTUM mRNA

PMID:25539665 PMID:26194646

NCBI chr10:106,431,572...106,438,654
Ensembl chr10:106,431,572...106,438,654

G

NADPH oxidase 1

increases expression

EXP

furan results in increased expression of NOX1 mRNA

NCBI chr X:101,572,338...101,625,571
Ensembl chr X:101,572,340...101,595,520

G

NADPH oxidase 4

decreases expression

EXP

furan results in decreased expression of NOX4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483

G

NADPH oxidase activator 1

increases expression

EXP

furan results in increased expression of NOXA1 mRNA

NCBI chr 3:28,293,643...28,309,828
Ensembl chr 3:28,293,658...28,304,022

G

NADPH oxidase organizer 1

increases expression

EXP

furan results in increased expression of NOXO1 mRNA

NCBI chr10:14,226,473...14,230,541
Ensembl chr10:14,228,205...14,230,541

G

neuronal PAS domain protein 1

decreases expression

EXP

furan results in decreased expression of NPAS1 mRNA

NCBI chr 1:86,295,509...86,316,018
Ensembl chr 1:86,295,515...86,314,893

G

neuronal PAS domain protein 2

decreases expression

EXP

furan results in decreased expression of NPAS2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037

G

nuclear protein, co-activator of histone transcription

decreases expression

EXP

furan results in decreased expression of NPAT mRNA

NCBI chr 8:62,829,141...62,867,065
Ensembl chr 8:62,829,185...62,867,065

G

neuropeptide B

increases expression

EXP

furan results in increased expression of NPB mRNA

NCBI chr10:106,382,307...106,385,566
Ensembl chr10:106,384,779...106,385,878

G

NPC1 like intracellular cholesterol transporter 1

increases expression

EXP

furan results in increased expression of NPC1L1 mRNA

NCBI chr14:85,285,387...85,305,050
Ensembl chr14:85,285,390...85,305,050

G

neural proliferation, differentiation and control, 1

increases expression

EXP

furan results in increased expression of NPDC1 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 3:28,618,601...28,624,591

G

neuropeptide FF receptor 1

decreases expression

EXP

furan results in decreased expression of NPFFR1 mRNA

NCBI chr20:30,082,604...30,116,752
Ensembl chr20:30,082,604...30,114,998

G

nucleophosmin 1

increases methylation

EXP

furan results in increased methylation of NPM1 gene

NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr X:18,245,740...18,256,024

G

nucleophosmin/nucleoplasmin 2

decreases expression

EXP

furan results in decreased expression of NPM2 mRNA

NCBI chr15:52,131,973...52,145,710
Ensembl chr15:52,132,058...52,139,027

G

natriuretic peptide B

increases expression

EXP

furan results in increased expression of NPPB mRNA

NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310

G

natriuretic peptide receptor 2

increases expression

EXP

furan results in increased expression of NPR2 mRNA

NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:62,678,367...62,697,343

G

natriuretic peptide receptor 3

increases expression

EXP

furan results in increased expression of NPR3 mRNA

NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066

G

neuropeptide VF precursor

decreases expression

EXP

furan results in decreased expression of NPVF mRNA

NCBI chr 4:81,043,128...81,047,045
Ensembl chr 4:81,043,128...81,047,045

G

neuropeptide W

increases expression

EXP

furan results in increased expression of NPW mRNA

PMID:25539665 PMID:26194646

NCBI chr10:14,184,819...14,186,155
Ensembl chr10:14,184,862...14,186,127

G

neuropeptide Y

decreases expression

EXP

furan results in decreased expression of NPY mRNA

NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310

G

neuropeptide Y receptor Y5

increases methylation

EXP

furan results in increased methylation of NPY5R gene

NCBI chr16:27,822,055...27,830,012
Ensembl chr16:27,816,065...27,830,290

G

NAD(P)H quinone dehydrogenase 1

increases methylation
increases expression
multiple interactions

EXP
ISO

furan results in increased methylation of NQO1 gene
furan results in increased expression of NQO1 mRNA
[Bromodeoxyuridine co-treated with furan] results in increased expression of NQO1 mRNA

PMID:15120968 PMID:22079235 PMID:24183702 PMID:24910943 PMID:25539665 More...

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 0, group B, member 2

increases expression
multiple interactions

ISO

furan results in increased expression of NR0B2 mRNA
rhodioloside inhibits the reaction [furan results in increased expression of NR0B2 mRNA]

NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475

G

nuclear receptor subfamily 1, group D, member 1

increases methylation

EXP

furan results in increased methylation of NR1D1 gene

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812

G

nuclear receptor subfamily 1, group H, member 4

increases methylation
multiple interactions
affects expression

EXP
ISO

furan results in increased methylation of NR1H4 gene
rhodioloside affects the reaction [furan affects the expression of NR1H4 mRNA]

PMID:22079235 PMID:32251705

NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389

G

nuclear receptor subfamily 1, group I, member 3

increases methylation

EXP

furan results in increased methylation of NR1I3 gene

NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370

G

nuclear receptor subfamily 3, group C, member 1

increases methylation

EXP

furan results in increased methylation of NR3C1 gene

NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843

G

nuclear receptor subfamily 4, group A, member 1

increases methylation

EXP

furan results in increased methylation of NR4A1 gene

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041

G

nuclear receptor subfamily 6, group A, member 1

increases expression

EXP

furan results in increased expression of NR6A1 mRNA

NCBI chr 3:42,904,832...43,094,622
Ensembl chr 3:42,904,832...43,092,951

G

neurotrophin receptor associated death domain

increases expression

EXP

furan results in increased expression of NRADD mRNA

NCBI chr 8:119,478,055...119,481,336
Ensembl chr 8:119,477,240...119,481,214

G

Notch-regulated ankyrin repeat protein

increases expression

EXP

furan results in increased expression of NRARP mRNA

NCBI chr 3:28,390,745...28,393,299
Ensembl chr 3:28,390,733...28,393,453

G

nuclear receptor binding protein 2

decreases expression

ISO
EXP

furan results in decreased expression of NRBP2 mRNA

PMID:24183702 PMID:25539665

NCBI chr 7:109,679,330...109,685,656
Ensembl chr 7:109,679,330...109,685,588

G

neuregulin 1

increases expression

ISO
EXP

furan results in increased expression of NRG1 mRNA

PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849

G

nuclear receptor interacting protein 1

decreases expression

EXP

furan results in decreased expression of NRIP1 mRNA

NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353

G

neuropilin 1

increases methylation

EXP

furan results in increased methylation of NRP1 gene

NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702

G

neuropilin 2

increases methylation
decreases expression

EXP
ISO

furan results in increased methylation of NRP2 gene
furan results in decreased expression of NRP2 mRNA

PMID:22079235 PMID:24183702

NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871

G

neurturin

decreases expression

EXP

furan results in decreased expression of NRTN mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:1,669,099...1,674,957
Ensembl chr 9:1,641,618...1,675,133

G

neurexin 1

decreases expression

EXP

furan results in decreased expression of NRXN1 mRNA

NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:8,935,523...10,077,374

G

NSA2 ribosome biogenesis factor

increases methylation

EXP

furan results in increased methylation of NSA2 gene

NCBI chr 2:30,177,753...30,184,004
Ensembl chr 2:30,177,702...30,184,031

G

nuclear receptor binding SET domain protein 1

increases methylation

EXP

furan results in increased methylation of NSD1 gene

NCBI chr17:9,317,085...9,431,528
Ensembl chr17:9,317,085...9,452,250

G

neuronal vesicle trafficking associated 1

increases expression
decreases methylation

EXP

furan results in increased expression of NSG1 mRNA
furan results in decreased methylation of NSG1 gene

NCBI chr14:76,861,079...76,882,822
Ensembl chr14:76,860,746...76,883,390

G

5'-nucleotidase, cytosolic IB

increases expression

EXP

furan results in increased expression of NT5C1B mRNA

NCBI chr 6:38,858,182...38,875,610
Ensembl chr 6:38,858,215...38,875,968

G

5'-nucleotidase domain containing 2

increases expression

EXP

furan results in increased expression of NT5DC2 mRNA

PMID:25539665 PMID:26194646

NCBI chr16:6,328,925...6,336,978
Ensembl chr16:6,328,523...6,336,980

G

5' nucleotidase, ecto

increases methylation

EXP

furan results in increased methylation of NT5E gene

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645

G

neurotrophin 3

decreases expression

EXP

furan results in decreased expression of NTF3 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349

G

netrin G2

increases methylation

EXP

furan results in increased methylation of NTNG2 gene

NCBI chr 3:32,889,856...32,949,032
Ensembl chr 3:32,890,575...32,943,821

G

neurotrophic receptor tyrosine kinase 1

increases expression

EXP

furan results in increased expression of NTRK1 mRNA

NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787

G

nucleobindin 1

increases methylation

EXP

furan results in increased methylation of NUCB1 gene

NCBI chr 1:105,104,793...105,135,730
Ensembl chr 1:105,104,793...105,135,837

G

nuclear distribution C, dynein complex regulator

increases methylation

EXP

furan results in increased methylation of NUDC gene

NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260

G

NudC domain containing 3

increases expression

EXP

furan results in increased expression of NUDCD3 mRNA

NCBI chr14:85,190,276...85,273,655
Ensembl chr14:85,188,285...85,272,883

G

nudix hydrolase 16

decreases expression

ISO

furan results in decreased expression of NUDT16 mRNA

NCBI chr 8:114,618,706...114,620,761
Ensembl chr 8:114,618,725...114,620,951

G

nudix hydrolase 17

increases expression

EXP

furan results in increased expression of NUDT17 mRNA

NCBI chr 2:186,930,305...186,932,797
Ensembl chr 2:186,930,305...186,932,797

G

nudix hydrolase 3

increases methylation

EXP

furan results in increased methylation of NUDT3 gene

NCBI chr20:5,636,184...5,688,770
Ensembl chr20:5,636,184...5,688,754

G

NUF2 component of NDC80 kinetochore complex

increases expression

EXP

furan results in increased expression of NUF2 mRNA

NCBI chr13:84,226,448...84,290,957
Ensembl chr13:84,226,509...84,255,598

G

nucleoporin 205

increases expression

EXP

furan results in increased expression of NUP205 mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:64,822,051...64,887,996
Ensembl chr 4:64,822,065...64,887,988

G

nucleoporin 210

increases expression

EXP

furan results in increased expression of NUP210 mRNA

NCBI chr 4:125,068,736...125,167,238
Ensembl chr 4:125,068,736...125,167,047

G

nucleoporin 50, pseudogene 1

increases methylation

EXP

furan results in increased methylation of SPG7 gene

NCBI chr 4:130,344,273...130,346,002
Ensembl chr 4:130,342,422...130,346,296

G

nucleoporin 62

increases methylation

EXP

furan results in increased methylation of NUP62 gene

NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710

G

nucleolar and spindle associated protein 1

increases expression

EXP

furan results in increased expression of NUSAP1 mRNA

NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237

G

nucleoredoxin-like 2

decreases expression

EXP

furan results in decreased expression of NXNL2 mRNA

NCBI chr17:14,182,849...14,187,595
Ensembl chr17:14,182,849...14,188,208

G

neurexophilin and PC-esterase domain family, member 2

decreases expression

ISO

furan results in decreased expression of NXPE2 mRNA

NCBI chr 8:57,558,250...57,596,039
Ensembl chr 8:57,558,645...57,592,171

G

neurexophilin and PC-esterase domain family, member 3

increases expression

EXP

furan results in increased expression of NXPE3 mRNA

NCBI chr11:58,195,951...58,246,739
Ensembl chr11:58,195,976...58,248,644

G

out at first homolog

decreases expression

EXP

furan results in decreased expression of OAF mRNA

PMID:25539665 PMID:26194646

NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285

G

2'-5' oligoadenylate synthetase 1A

decreases expression

EXP

furan results in decreased expression of OAS1A mRNA

NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128

G

2-5 oligoadenylate synthetase 1B

decreases expression

EXP

furan results in decreased expression of OAS1B mRNA

NCBI chr12:41,385,184...41,395,891
Ensembl chr12:41,384,678...41,395,914

G

2 ' -5 ' oligoadenylate synthetase 1I

decreases expression

EXP

furan results in decreased expression of OAS1I mRNA

NCBI chr12:41,285,201...41,297,242

G

2 ' -5 ' oligoadenylate synthetase 1K

decreases expression

EXP

furan results in decreased expression of OAS1K mRNA

NCBI chr12:41,423,100...41,432,330
Ensembl chr12:41,422,937...41,432,330

G

2'-5'-oligoadenylate synthetase-like

decreases expression

EXP

furan results in decreased expression of OASL mRNA

NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483

G

ornithine aminotransferase

decreases expression

EXP

furan results in decreased expression of OAT mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754

G

ornithine decarboxylase antizyme 3

decreases methylation

EXP

furan results in decreased methylation of OAZ3 gene

NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:184,762,245...184,771,428

G

alpha-2u globulin PGCL4

decreases expression

EXP

furan results in decreased expression of OBP3 mRNA

PMID:15120968 PMID:26194646

NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675

G

occludin

multiple interactions
decreases expression

ISO

rhodioloside affects the reaction [furan results in decreased expression of OCLN protein]

NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411

G

ornithine decarboxylase 1

increases expression

ISO
EXP

furan results in increased expression of ODC1 mRNA

PMID:20124500 PMID:24183702 PMID:25539665

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146

G

outer dense fiber of sperm tails 2-like

increases expression

EXP

furan results in increased expression of ODF2L mRNA

NCBI chr 2:236,696,158...236,733,090
Ensembl chr 2:236,696,389...236,733,086

G

Ofd1 centriole and centriolar satellite protein

increases methylation

EXP

furan results in increased methylation of OFD1 gene

NCBI chr X:31,647,000...31,687,768
Ensembl chr X:31,647,000...31,687,884

G

oxoglutarate dehydrogenase L

increases expression

EXP

furan results in increased expression of OGDHL mRNA

NCBI chr16:7,584,666...7,610,705
Ensembl chr16:7,584,657...7,610,698

G

8-oxoguanine DNA glycosylase

decreases expression

EXP

furan results in decreased expression of OGG1 mRNA

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604

G

osteoglycin

increases expression

EXP

furan results in increased expression of OGN mRNA

NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252

G

Obg-like ATPase 1

increases methylation

EXP

furan results in increased methylation of OLA1 gene

NCBI chr 3:78,374,440...78,493,401
Ensembl chr 3:78,374,441...78,492,012

G

olfactomedin-like 1

decreases expression
increases expression

ISO
EXP

furan results in decreased expression of OLFML1 mRNA
furan results in increased expression of OLFML1 mRNA

PMID:24183702 PMID:27387713

NCBI chr 1:170,889,912...170,914,300
Ensembl chr 1:170,889,980...170,915,762

G

olfactomedin-like 2A

increases expression

EXP

furan results in increased expression of OLFML2A mRNA

NCBI chr 3:43,098,299...43,127,621
Ensembl chr 3:43,098,299...43,127,621

G

olfactomedin-like 2B

increases methylation
increases expression

EXP

furan results in increased methylation of OLFML2B gene
furan results in increased expression of OLFML2B mRNA

PMID:22079235 PMID:27387713

NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342

G

olfactomedin-like 3

increases expression

EXP

furan results in increased expression of OLFML3 mRNA

NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494

G

oxidized low density lipoprotein receptor 1

increases expression

EXP

furan results in increased expression of OLR1 mRNA

NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598

G

olfactory receptor 1433

increases methylation

EXP

furan results in increased methylation of OLR1433 gene

NCBI chr10:43,542,833...43,546,698

G

olfactory receptor gene Olr1493

decreases expression

EXP

furan results in decreased expression of OLR1493 mRNA

NCBI chr10:58,994,200...58,995,138
Ensembl chr10:58,994,200...58,995,138

G

olfactory receptor 59

decreases expression

EXP

furan results in decreased expression of OLR59 mRNA

NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265

G

osteomodulin

decreases expression

EXP

furan results in decreased expression of OMD mRNA

PMID:25539665 PMID:26194646

NCBI chr17:15,266,646...15,274,870
Ensembl chr17:15,266,646...15,274,870

G

one cut homeobox 1

decreases expression

EXP

furan results in decreased expression of ONECUT1 mRNA

NCBI chr 8:84,480,066...84,507,848
Ensembl chr 8:84,480,305...84,508,124

G

opsin 3

increases expression

EXP

furan results in increased expression of OPN3 mRNA

NCBI chr13:90,121,560...90,152,076
Ensembl chr13:90,121,560...90,152,076

G

opsin 4

increases methylation

EXP

furan results in increased methylation of OPN4 gene

NCBI chr16:9,926,638...9,935,810
Ensembl chr16:9,926,902...9,949,928

G

opioid receptor, mu 1

decreases expression

EXP

furan results in decreased expression of OPRM1 mRNA

NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756

G

olfactory receptor family 10 subfamily A member 48B

increases expression

EXP

furan results in increased expression of OR10A48 mRNA

NCBI chr 1:172,228,688...172,229,623
Ensembl chr 1:172,228,688...172,229,623

G

olfactory receptor family 10 subfamily AL member 5B

decreases expression

EXP

furan results in decreased expression of OR10AL5B mRNA

NCBI chr20:803,673...816,671
Ensembl chr20:743,522...816,076

G

olfactory receptor family 10 subfamily G member 9B

decreases methylation

EXP

furan results in decreased methylation of OR10G9B gene

NCBI chr 8:49,255,369...49,256,301
Ensembl chr 8:49,255,369...49,256,301

G

olfactory receptor family 10 subfamily J member 7

decreases expression

EXP

furan results in decreased expression of OR10J7 mRNA

NCBI chr13:88,180,125...88,181,057
Ensembl chr13:88,180,125...88,181,057

G

olfactory receptor family 10 subfamily P member 1

decreases methylation

EXP

furan results in decreased methylation of OR10P1 gene

NCBI chr 7:6,123,347...6,124,270
Ensembl chr 7:6,123,347...6,124,270

G

olfactory receptor family 10 subfamily P member 22

decreases expression

EXP

furan results in decreased expression of OR10P22 mRNA

NCBI chr 7:2,015,370...2,016,308
Ensembl chr 7:2,015,171...2,016,366

G

olfactory receptor family 10 subfamily Q member 1

decreases expression

EXP

furan results in decreased expression of OR10Q1 mRNA

NCBI chr 1:220,285,910...220,286,866
Ensembl chr 1:220,285,910...220,286,866

G

olfactory receptor family 12 subfamily D member 13

decreases methylation

EXP

furan results in decreased methylation of OR12D13 gene

NCBI chr20:1,250,936...1,251,877

G

olfactory receptor family 12 subfamily J member 3

decreases methylation
decreases expression

EXP

furan results in decreased methylation of OR12J3 gene
furan results in decreased expression of OR12J3 mRNA

PMID:22079235 PMID:25539665

NCBI chr 1:204,694,331...204,695,254
Ensembl chr 1:204,694,331...204,695,254

G

olfactory receptor family 13 subfamily A member 18C

decreases methylation

EXP

furan results in decreased methylation of OR13A18C gene

NCBI chr 1:205,040,415...205,041,347
Ensembl chr 1:205,040,409...205,041,347

G

olfactory receptor family 13 subfamily A member 19C

decreases methylation

EXP

furan results in decreased methylation of OR13A19C gene

NCBI chr 1:204,763,875...204,764,804
Ensembl chr 1:204,763,875...204,764,804

G

olfactory receptor family 13 subfamily P member 5

decreases expression

EXP

furan results in decreased expression of OR13P5 mRNA

NCBI chr 5:137,547,109...137,550,742
Ensembl chr 5:137,549,795...137,550,742

G

olfactory receptor family 1 subfamily AD member 1

decreases expression

EXP

furan results in decreased expression of OR1AD1 mRNA

NCBI chr10:35,800,754...35,801,677
Ensembl chr10:35,800,754...35,801,677

G

olfactory receptor family 1 subfamily O member 2C

decreases expression

EXP

furan results in decreased expression of OR1O2C mRNA

NCBI chr20:1,078,730...1,079,659
Ensembl chr20:1,078,730...1,079,659

G

olfactory receptor family 2 subfamily B member 4

decreases expression

EXP

furan results in decreased expression of OR2B4 mRNA

NCBI chr20:711,731...712,675
Ensembl chr20:711,731...712,675

G

olfactory receptor family 2 subfamily T member 1

increases expression

EXP

furan results in increased expression of OR2T1 mRNA

NCBI chr15:13,391,080...13,392,033
Ensembl chr15:13,391,080...13,392,033
Ensembl chr15:13,391,080...13,392,033

G

olfactory receptor family 2 subfamily Y member 1I

increases methylation

EXP

furan results in increased methylation of OR2Y1 gene

NCBI chr10:34,238,313...34,239,242

G

olfactory receptor family 3 subfamily A member 1

decreases expression

EXP

furan results in decreased expression of OR3A1 mRNA

NCBI chr10:59,645,520...59,646,467
Ensembl chr10:59,645,520...59,646,467

G

olfactory receptor family 4 subfamily F member 53B

decreases expression

EXP

furan results in decreased expression of OR4F53B mRNA

NCBI chr 3:118,322,435...118,323,373
Ensembl chr 3:118,322,435...118,323,373

G

olfactory receptor family 4 subfamily F member 60B

decreases expression

EXP

furan results in decreased expression of OR4F60B mRNA

NCBI chr 3:119,096,342...119,097,277
Ensembl chr 3:119,096,342...119,097,277

G

olfactory receptor family 4 subfamily K member 35

decreases expression

EXP

furan results in decreased expression of OR4K35 mRNA

NCBI chr 3:118,334,792...118,335,703
Ensembl chr 3:118,334,792...118,335,703

G

olfactory receptor family 4 subfamily K member 48

increases methylation

EXP

furan results in increased methylation of OR4K48 gene

NCBI chr 3:118,675,046...118,675,984
Ensembl chr 3:118,675,046...118,675,984

G

olfactory receptor family 4 subfamily M member 1

decreases methylation

EXP

furan results in decreased methylation of OR4M1 gene

NCBI chr15:25,980,799...25,981,740
Ensembl chr15:25,980,799...25,981,740

G

olfactory receptor family 4 subfamily X member 11C

decreases methylation

EXP

furan results in decreased methylation of OR4X11C gene

NCBI chr 3:96,596,324...96,597,253
Ensembl chr 3:96,596,324...96,597,253

G

olfactory receptor family 51 subfamily K member 1

increases methylation

EXP

furan results in increased methylation of OR51K1 gene

NCBI chr 1:167,898,735...167,899,685
Ensembl chr 1:167,898,735...167,899,685

G

olfactory receptor family 51 subfamily L member 1

increases methylation

EXP

furan results in increased methylation of OR51L1 gene

NCBI chr 1:166,928,111...166,929,058
Ensembl chr 1:166,928,111...166,929,058

G

olfactory receptor family 52 subfamily H member 7

decreases expression

EXP

furan results in decreased expression of OR52H7 mRNA

NCBI chr 1:168,247,795...168,248,769
Ensembl chr 1:168,247,795...168,248,769

G

olfactory receptor family 5 subfamily A member 3

decreases expression

EXP

furan results in decreased expression of OR5A3 mRNA

NCBI chr 1:218,831,482...218,832,438
Ensembl chr 1:218,831,482...218,832,438

G

olfactory receptor family 5 subfamily AN member 6

decreases expression

EXP

furan results in decreased expression of OR5AN6 mRNA

NCBI chr 1:218,790,201...218,791,163
Ensembl chr 1:218,790,201...218,791,163

G

olfactory receptor family 5 subfamily BB member 12

decreases expression

EXP

furan results in decreased expression of OR5BB12 mRNA

NCBI chr 1:218,545,301...218,546,266
Ensembl chr 1:218,545,301...218,546,266

G

olfactory receptor family 5 subfamily BH member 3

increases methylation

EXP

furan results in increased methylation of OR5BH3 gene

NCBI chr X:134,167,584...134,168,507
Ensembl chr X:134,167,584...134,168,513

G

olfactory receptor family 5 subfamily H member 27

increases expression

EXP

furan results in increased expression of OR5H27 mRNA

NCBI chr11:54,620,574...54,626,346

G

olfactory receptor family 5 subfamily M member 11

decreases methylation

EXP

furan results in decreased methylation of OR5M11 gene

NCBI chr 3:91,424,233...91,425,207
Ensembl chr 3:91,424,233...91,425,207
Ensembl chr 3:91,424,233...91,425,207

G

olfactory receptor family 5 subfamily M member 8

decreases expression

EXP

furan results in decreased expression of OR5M8 mRNA

NCBI chr 3:91,439,317...91,442,419
Ensembl chr 3:91,441,436...91,442,419

G

olfactory receptor family 5 subfamily O member 1

decreases expression

EXP

furan results in decreased expression of OR5O1 mRNA

NCBI chr X:133,891,870...133,892,808
Ensembl chr X:133,891,870...133,892,829

G

olfactory receptor family 5 subfamily W member 11

increases methylation

EXP

furan results in increased methylation of OR5W11 gene

NCBI chr 3:93,504,527...93,505,456
Ensembl chr 3:93,504,527...93,505,456

G

olfactory receptor family 6 subfamily B member 6

decreases expression

EXP

furan results in decreased expression of OR6B2 mRNA

NCBI chr 1:170,224,524...170,225,468
Ensembl chr 1:170,224,524...170,225,468

G

olfactory receptor family 6 subfamily D member 13B

decreases expression

EXP

furan results in decreased expression of OR6D13B mRNA

NCBI chr 4:151,346,015...151,346,998
Ensembl chr 4:151,346,015...151,346,998

G

olfactory receptor family 6 subfamily F member 1

decreases expression

EXP

furan results in decreased expression of OR6F1 mRNA

NCBI chr 1:149,301,451...149,302,377
Ensembl chr 1:149,301,451...149,302,377

G

olfactory receptor family 6 subfamily F member 2

decreases expression

EXP

furan results in decreased expression of OR6F2 mRNA

NCBI chr 1:204,406,568...204,407,503
Ensembl chr 1:204,406,550...204,407,503

G

olfactory receptor family 6 subfamily K member 8

increases expression

EXP

furan results in increased expression of OR6K8 mRNA

NCBI chr13:88,712,908...88,713,855
Ensembl chr13:88,712,908...88,713,855

G

olfactory receptor family 7 subfamily C member 70

increases methylation

EXP

furan results in increased methylation of OR7C70 gene

NCBI chr 7:11,461,214...11,468,390
Ensembl chr 7:11,461,214...11,462,176

G

olfactory receptor family 7 subfamily E member 169

decreases expression

EXP

furan results in decreased expression of OR7E169 mRNA

NCBI chr 8:26,358,956...26,359,912
Ensembl chr 8:26,358,956...26,359,912

G

olfactory receptor family 7 subfamily E member 176

decreases expression

EXP

furan results in decreased expression of OR7E176 mRNA

NCBI chr 8:26,891,487...26,894,233
Ensembl chr 8:26,756,959...26,839,401
Ensembl chr 8:26,756,959...26,839,401

G

olfactory receptor family 8 subfamily B member 3C

decreases methylation

EXP

furan results in decreased methylation of OR8B3C gene

NCBI chr 8:47,379,226...47,380,176
Ensembl chr 8:47,379,226...47,380,176

G

olfactory receptor family 8 subfamily B member 44B

increases methylation

EXP

furan results in increased methylation of OR8B44B gene

NCBI chr 8:47,384,532...47,385,464
Ensembl chr 8:47,384,532...47,385,464

G

olfactory receptor family 8 subfamily B member 54C

decreases expression

EXP

furan results in decreased expression of OR8B54C mRNA

NCBI chr 8:47,887,638...47,888,579
Ensembl chr 8:47,887,638...47,888,579

G

olfactory receptor family 8 subfamily G member 36B

decreases expression

EXP

furan results in decreased expression of OR8G36B mRNA

NCBI chr 8:48,700,906...48,701,859
Ensembl chr 8:48,700,906...48,701,859

G

olfactory receptor family 8 subfamily K member 25

decreases expression

EXP

furan results in decreased expression of OR8K25 mRNA

NCBI chr 3:91,820,173...91,821,126
Ensembl chr 3:91,820,173...91,821,126

G

olfactory receptor family 9 subfamily K member 7

decreases methylation

EXP

furan results in decreased methylation of OR9K7 gene

NCBI chr 7:7,670,898...7,671,866

G

olfactory receptor family 9 subfamily S member 13

decreases expression

EXP

furan results in decreased expression of OR9S13 mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:100,632,070...100,640,831
Ensembl chr 9:100,631,992...100,654,205

G

olfactory receptor family 9 subfamily S member 14

decreases expression

EXP

furan results in decreased expression of OR9S14 mRNA

NCBI chr 9:100,620,818...100,621,786
Ensembl chr 9:100,620,818...100,621,786

G

olfactory receptor family 9 subfamily S member 15

decreases expression
decreases methylation

EXP

furan results in decreased expression of OR9S15 mRNA
furan results in decreased methylation of OR9S15 gene

PMID:22079235 PMID:25539665

NCBI chr 9:100,597,031...100,598,002
Ensembl chr 9:100,597,031...100,598,002

G

origin recognition complex, subunit 1

increases expression

EXP

furan results in increased expression of ORC1 mRNA

NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:128,552,991...128,577,071

G

orosomucoid 1

increases methylation

EXP

furan results in increased methylation of ORM1 gene

NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:81,788,395...81,791,667

G

oxysterol binding protein-like 11

increases methylation

EXP

furan results in increased methylation of OSBPL11 gene

NCBI chr11:81,038,759...81,121,887
Ensembl chr11:81,038,985...81,101,299

G

oxysterol binding protein-like 6

increases methylation
decreases expression

EXP

furan results in increased methylation of OSBPL6 gene
furan results in decreased expression of OSBPL6 mRNA

PMID:22079235 PMID:25539665

NCBI chr 3:81,751,020...81,948,186
Ensembl chr 3:81,750,982...81,946,615

G

organic solute carrier partner 1

increases expression

EXP

furan results in increased expression of OSCP1 mRNA

NCBI chr 5:143,618,186...143,649,765
Ensembl chr 5:143,615,360...143,663,986

G

O-sialoglycoprotein endopeptidase-like 1

increases expression

EXP

furan results in increased expression of OSGEPL1 mRNA

NCBI chr 9:55,707,389...55,725,325
Ensembl chr 9:55,707,392...55,721,346

G

oxidative stress induced growth inhibitor 1

increases expression
decreases expression

ISO
EXP

furan results in increased expression of OSGIN1 mRNA
furan results in decreased expression of OSGIN1 mRNA

PMID:24183702 PMID:26194646 PMID:37517673

NCBI chr19:64,380,336...64,409,165
Ensembl chr19:64,401,173...64,409,162

G

oxidative stress induced growth inhibitor family member 2

increases expression

EXP

furan results in increased expression of OSGIN2 mRNA

NCBI chr 5:34,297,417...34,316,353
Ensembl chr 5:34,297,417...34,316,931

G

odd-skipped related transcription factor 1

increases expression

EXP

furan results in increased expression of OSR1 mRNA

NCBI chr 6:38,088,688...38,100,010
Ensembl chr 6:38,093,011...38,100,021

G

ornithine transcarbamylase

affects binding

EXP

furan binds to OTC protein

NCBI chr X:15,126,358...15,202,473
Ensembl chr X:15,126,358...15,239,555

G

otopetrin 3

increases methylation

EXP

furan results in increased methylation of OTOP3 gene

NCBI chr10:101,076,307...101,087,704
Ensembl chr10:101,076,210...101,087,697

G

OTU deubiquitinase 7B

increases expression

ISO

furan results in increased expression of OTUD7B mRNA

NCBI chr 2:186,350,811...186,411,461
Ensembl chr 2:186,350,798...186,409,440

G

ovo like transcriptional repressor 1

decreases methylation
increases expression

EXP

furan results in decreased methylation of OVOL1 gene
furan results in increased expression of OVOL1 mRNA

NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:212,284,605...212,296,106

G

purinergic receptor P2X 7

decreases expression

EXP

furan results in decreased expression of P2RX7 mRNA

PMID:25539665 PMID:27387713

NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193

G

purinergic receptor P2Y1

multiple interactions

ISO

[Bromodeoxyuridine co-treated with furan] affects the expression of P2RY1 mRNA

NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:147,390,681...147,398,027

G

purinergic receptor P2Y12

increases methylation
increases expression

EXP

furan results in increased methylation of P2RY12 gene
furan results in increased expression of P2RY12 mRNA

PMID:22079235 PMID:27387713

NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:145,629,967...145,633,410

G

purinergic receptor P2Y2

decreases expression

EXP

furan results in decreased expression of P2RY2 mRNA

NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:164,759,213...164,781,852

G

pyrimidinergic receptor P2Y6

increases expression

EXP

furan results in increased expression of P2RY6 mRNA

NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588

G

prolyl 3-hydroxylase 3

increases expression

EXP

furan results in increased expression of P3H3 mRNA

NCBI chr 4:159,332,514...159,348,428
Ensembl chr 4:159,332,434...159,348,004

G

prolyl 3-hydroxylase family member 4

increases methylation

EXP

furan results in increased methylation of P3H4 gene

NCBI chr10:85,838,528...85,845,476
Ensembl chr10:85,838,528...85,845,476

G

prolyl 4-hydroxylase subunit beta

affects binding

EXP

furan binds to P4HB protein

NCBI chr10:106,335,300...106,346,911
Ensembl chr10:106,335,300...106,346,911

G

poly(A) binding protein, cytoplasmic 2

increases methylation

EXP

furan results in increased methylation of PABPC2 gene

NCBI chr18:31,905,327...31,907,595
Ensembl chr18:31,905,128...31,929,299

G

poly(A) binding protein, cytoplasmic 4

increases expression

EXP

furan results in increased expression of PABPC4 mRNA

NCBI chr 5:140,847,835...140,864,089
Ensembl chr 5:140,848,225...140,864,087

G

proton activated chloride channel 1

decreases methylation
increases expression

EXP

furan results in decreased methylation of PACC1 gene
furan results in increased expression of PACC1 mRNA

NCBI chr13:105,435,772...105,460,877
Ensembl chr13:105,435,799...105,461,095

G

parkin coregulated

increases expression
increases methylation

EXP

furan results in increased expression of PACRG mRNA
furan results in increased methylation of PACRG gene

PMID:22079235 PMID:25539665

NCBI chr 1:52,430,390...52,853,272
Ensembl chr 1:52,430,284...52,853,269

G

protein kinase C and casein kinase substrate in neurons 2

decreases methylation

EXP

furan results in decreased methylation of PACSIN2 gene

NCBI chr 7:116,385,571...116,478,609
Ensembl chr 7:116,384,190...116,478,537

G

peptidyl arginine deiminase 2

increases expression

EXP

furan results in increased expression of PADI2 mRNA

NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662

G

peptidyl arginine deiminase 3

increases expression

EXP

furan results in increased expression of PADI3 mRNA

NCBI chr 5:158,372,764...158,400,193
Ensembl chr 5:158,372,764...158,400,193

G

peptidyl arginine deiminase 4

increases expression

EXP

furan results in increased expression of PADI4 mRNA

NCBI chr 5:158,324,417...158,357,466
Ensembl chr 5:158,324,417...158,360,422

G

phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase

affects binding

EXP

furan binds to PAICS protein

NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027

G

phosphatase domain containing, paladin 1

decreases expression

EXP

furan results in decreased expression of PALD1 mRNA

NCBI chr20:29,812,650...29,877,733
Ensembl chr20:29,812,650...29,850,063

G

protein associated with LIN7 2, MAGUK p55 family member

decreases expression
increases methylation

EXP

furan results in decreased expression of PALS2 mRNA
furan results in increased methylation of PALS2 gene

PMID:22079235 PMID:27387713

NCBI chr 4:80,504,298...80,584,951
Ensembl chr 4:80,455,657...80,584,950

G

peptidylglycine alpha-amidating monooxygenase

increases methylation

EXP

furan results in increased methylation of PAM gene

NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:105,445,929...105,719,285

G

poly(A) specific ribonuclease subunit PAN2

decreases methylation

EXP

furan results in decreased methylation of PAN2 gene

NCBI chr 7:1,313,654...1,332,252
Ensembl chr 7:1,313,655...1,332,252

G

pannexin 2

increases expression

EXP

furan results in increased expression of PANX2 mRNA

NCBI chr 7:122,018,937...122,032,009
Ensembl chr 7:122,018,937...122,032,004

G

progestin and adipoQ receptor family member 4

decreases expression

EXP

furan results in decreased expression of PAQR4 mRNA

NCBI chr10:13,263,559...13,267,237
Ensembl chr10:13,263,559...13,267,173

G

progestin and adipoQ receptor family member 9

decreases expression

EXP

furan results in decreased expression of PAQR9 mRNA

NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285

G

poly (ADP-ribose) polymerase family, member 14

decreases expression

EXP

furan results in decreased expression of PARP14 mRNA

PMID:25539665 PMID:26194646

NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195

G

poly (ADP-ribose) polymerase 2

decreases expression

EXP

furan results in decreased expression of PARP2 mRNA

NCBI chr15:26,494,722...26,517,893
Ensembl chr15:26,494,731...26,517,891

G

poly (ADP-ribose) polymerase family, member 6

increases expression

EXP

furan results in increased expression of PARP6 mRNA

NCBI chr 8:68,912,393...68,944,904
Ensembl chr 8:68,917,388...68,944,898

G

PARP1 binding protein

increases expression

EXP

furan results in increased expression of PARPBP mRNA

NCBI chr 7:24,398,897...24,468,330
Ensembl chr 7:24,398,897...24,464,744

G

PAS domain containing serine/threonine kinase

increases expression

EXP

furan results in increased expression of PASK mRNA

NCBI chr 9:101,291,673...101,333,288
Ensembl chr 9:101,291,676...101,332,504

G

pro-apoptotic WT1 regulator

decreases methylation

EXP

furan results in decreased methylation of PAWR gene

NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492

G

paired box 3

decreases expression

EXP

furan results in decreased expression of PAX3 mRNA

NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141

G

paired box 8

increases expression

EXP

furan results in increased expression of PAX8 mRNA

NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:27,584,002...27,640,631

G

PDZ binding kinase

increases expression

EXP

furan results in increased expression of PBK mRNA

NCBI chr15:44,198,506...44,209,572
Ensembl chr15:44,198,544...44,209,570

G

pyruvate carboxylase

decreases expression

EXP

furan results in decreased expression of PC mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940

G

protocadherin 18

decreases expression

EXP

furan results in decreased expression of PCDH18 mRNA

NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826

G

protocadherin 19

increases expression

EXP

furan results in increased expression of PCDH19 mRNA

NCBI chr X:101,061,002...101,166,777
Ensembl chr X:101,065,263...101,165,269

G

protocadherin alpha 10

increases methylation

EXP

furan results in increased methylation of PCDHA10 gene

G

protocadherin alpha 12

increases methylation

EXP

furan results in increased methylation of PCDHA12 gene

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 13

increases methylation

EXP

furan results in increased methylation of PCDHA13 gene

G

protocadherin alpha 5

increases methylation

EXP

furan results in increased methylation of PCDHA5 gene

G

protocadherin alpha 9

increases methylation

EXP

furan results in increased methylation of PCDHA9 gene

G

protocadherin alpha subfamily C, 2

increases expression

EXP

furan results in increased expression of PCDHAC2 mRNA

Ensembl chr18:28,855,256...29,120,227

G

protocadherin beta 21

increases expression

EXP

furan results in increased expression of PCDHB9 mRNA

NCBI chr18:29,492,219...29,495,152

G

protocadherin beta 3

increases methylation

EXP

furan results in increased methylation of PCDHB3 gene

NCBI chr18:29,285,675...29,288,229

G

protocadherin gamma subfamily A, 10

increases methylation

EXP

furan results in increased methylation of PCDHGA10 gene

NCBI chr18:29,825,926...29,919,095

G

protocadherin gamma subfamily A, 11

increases methylation

EXP

furan results in increased methylation of PCDHGA11 gene

NCBI chr18:29,834,606...29,919,095

G

protocadherin gamma subfamily A, 12

increases methylation

EXP

furan results in increased methylation of PCDHGA12 gene

NCBI chr18:29,843,897...29,919,095

G

protocadherin gamma subfamily A, 3

increases methylation

EXP

furan results in increased methylation of PCDHGA3 gene

NCBI chr18:29,750,383...29,919,095

G

protocadherin gamma subfamily A, 5

increases methylation

EXP

furan results in increased methylation of PCDHGA5 gene

NCBI chr18:29,770,940...29,919,095

G

protocadherin gamma subfamily A, 9

increases methylation

EXP

furan results in increased methylation of PCDHGA9 gene

NCBI chr18:29,815,845...29,919,095

G

protocadherin gamma subfamily B, 2

decreases expression

EXP

furan results in decreased expression of PCDHGB2 mRNA

G

protocadherin gamma subfamily B, 7

increases methylation

EXP

furan results in increased methylation of PCDHGB7 gene

NCBI chr18:29,830,362...29,919,098
Ensembl chr18:29,799,669...29,919,101

G

protocadherin gamma subfamily B, 8

increases methylation

EXP

furan results in increased methylation of PCDHGB8 gene

NCBI chr18:29,839,560...29,919,095

G

polycomb group ring finger 6

increases methylation

EXP

furan results in increased methylation of PCGF6 gene

NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266

G

phosphoenolpyruvate carboxykinase 1

decreases expression

EXP

furan results in decreased expression of PCK1 mRNA

NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561

G

PCNA clamp associated factor

increases expression

EXP

furan results in increased expression of PCLAF mRNA

NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106

G

proliferating cell nuclear antigen

increases expression

EXP

furan results in increased expression of PCNA mRNA

PMID:20124500 PMID:22079235

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

procollagen C-endopeptidase enhancer 2

increases expression

EXP

furan results in increased expression of PCOLCE2 mRNA

NCBI chr 8:105,073,086...105,130,725
Ensembl chr 8:105,073,086...105,145,160

G

Purkinje cell protein 4-like 1

decreases expression

ISO

furan results in decreased expression of PCP4L1 mRNA

NCBI chr13:86,121,463...86,145,097
Ensembl chr13:86,121,464...86,144,899

G

proprotein convertase subtilisin/kexin type 1

decreases expression

EXP

furan results in decreased expression of PCSK1 mRNA

NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:6,129,592...6,176,974

G

proprotein convertase subtilisin/kexin type 4

decreases expression

ISO

furan results in decreased expression of PCSK4 mRNA

NCBI chr 7:10,032,040...10,040,263
Ensembl chr 7:10,031,988...10,040,255

G

phosphatidylcholine transfer protein

increases methylation

EXP

furan results in increased methylation of PCTP gene

NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432

G

phosphate cytidylyltransferase 1A, choline

increases expression

EXP

furan results in increased expression of PCYT1A mRNA

NCBI chr11:81,818,914...81,862,623
Ensembl chr11:81,819,285...81,862,395

G

phosphodiesterase 1A

decreases expression

EXP

furan results in decreased expression of PDE1A mRNA

NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212

G

phosphodiesterase 4B

decreases methylation

EXP

furan results in decreased methylation of PDE4B gene

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267

G

phosphodiesterase 5A

decreases expression
decreases methylation
increases expression

EXP

furan results in decreased expression of PDE5A mRNA
furan results in decreased methylation of PDE5A gene
furan results in increased expression of PDE5A mRNA

PMID:25539665 PMID:27387713

NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298

G

phosphodiesterase 6A

increases methylation

EXP

furan results in increased methylation of PDE6A gene

NCBI chr18:56,947,249...57,019,015
Ensembl chr18:56,947,249...57,019,015

G

phosphodiesterase 6C

increases expression

EXP

furan results in increased expression of PDE6C mRNA

NCBI chr 1:245,322,015...245,377,874
Ensembl chr 1:245,322,015...245,377,852

G

phosphodiesterase 9A

increases expression

EXP

furan results in increased expression of PDE9A mRNA

NCBI chr20:9,471,136...9,564,286
Ensembl chr20:9,471,167...9,564,286

G

platelet derived growth factor subunit A

increases expression

ISO

furan results in increased expression of PDGFA mRNA

PMID:24183702 PMID:37517673

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322

G

platelet derived growth factor C

increases methylation

EXP

furan results in increased methylation of PDGFC gene

NCBI chr 2:168,613,409...168,791,575
Ensembl chr 2:168,614,353...168,791,573

G

platelet derived growth factor D

increases expression

EXP

furan results in increased expression of PDGFD mRNA

NCBI chr 8:11,773,335...12,007,277
Ensembl chr 8:11,773,475...12,007,271

G

platelet derived growth factor receptor alpha

decreases methylation
increases expression

EXP

furan results in decreased methylation of PDGFRA gene
furan results in increased expression of PDGFRA mRNA

NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516

G

platelet derived growth factor receptor beta

increases expression

EXP

furan results in increased expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

platelet-derived growth factor receptor-like

increases expression

EXP

furan results in increased expression of PDGFRL mRNA

PMID:25539665 PMID:27387713

NCBI chr16:58,051,421...58,111,327
Ensembl chr16:58,051,440...58,111,327

G

protein disulfide isomerase family A, member 2

increases methylation

EXP

furan results in increased methylation of PDIA2 gene

NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396

G

protein disulfide isomerase family A, member 3

affects binding

EXP

furan binds to PDIA3 protein

NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:128,841,917...128,867,327

G

pyruvate dehydrogenase kinase 4

increases methylation

EXP

furan results in increased methylation of PDK4 gene

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381

G

PDZ and LIM domain 2

increases expression

EXP

furan results in increased expression of PDLIM2 mRNA

NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958

G

PDZ and LIM domain 4

increases expression

EXP

furan results in increased expression of PDLIM4 mRNA

NCBI chr10:38,699,444...38,713,696
Ensembl chr10:38,699,444...38,713,659

G

podoplanin

increases expression

EXP

furan results in increased expression of PDPN mRNA

NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637

G

PDS5 cohesin associated factor A

decreases expression

EXP

furan results in decreased expression of PDS5A mRNA

NCBI chr14:42,905,734...43,004,740
Ensembl chr14:42,905,328...43,004,740

G

pancreatic and duodenal homeobox 1

increases expression

EXP

furan results in increased expression of PDX1 mRNA

NCBI chr12:12,793,957...12,799,156
Ensembl chr12:12,793,957...12,799,156

G

PDZ domain containing 7

decreases expression

EXP

furan results in decreased expression of PDZD7 mRNA

NCBI chr 1:253,837,454...253,856,919
Ensembl chr 1:253,837,459...253,855,999

G

PDZ domain containing 1

affects binding

EXP

furan binds to PDZK1 protein

NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806

G

PDZ domain containing RING finger 3

decreases expression

EXP

furan results in decreased expression of PDZRN3 mRNA

NCBI chr 4:135,327,082...135,553,294
Ensembl chr 4:135,327,082...135,553,294

G

proliferation and apoptosis adaptor protein 15

decreases methylation
increases expression

EXP

furan results in decreased methylation of PEA15A gene
furan results in increased expression of PEA15A mRNA

NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859

G

paternally expressed 12

decreases expression

EXP

furan results in decreased expression of PEG12 mRNA

NCBI chr 1:125,374,399...125,377,002
Ensembl chr 1:125,373,287...125,377,374

G

proenkephalin

increases expression

EXP

furan results in increased expression of PENK mRNA

NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705

G

period circadian regulator 2

increases expression
decreases expression

EXP

furan results in increased expression of PER2 mRNA
furan results in decreased expression of PER2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993

G

period circadian regulator 3

increases expression

EXP

furan results in increased expression of PER3 mRNA

NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999

G

pescadillo ribosomal biogenesis factor 1

increases expression

EXP

furan results in increased expression of PES1 mRNA

NCBI chr14:83,074,346...83,090,726
Ensembl chr14:83,074,319...83,091,718

G

peroxisomal biogenesis factor 26

increases methylation

EXP

furan results in increased methylation of PEX26 gene

NCBI chr 4:156,085,967...156,099,096
Ensembl chr 4:156,086,960...156,099,093

G

peroxisomal biogenesis factor 6

increases expression

EXP

furan results in increased expression of PEX6 mRNA

NCBI chr 9:21,755,747...21,767,939
Ensembl chr 9:21,755,751...21,767,908

G

platelet factor 4

decreases expression

EXP

furan results in decreased expression of PF4 mRNA

NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392

G

phosphoribosylformylglycinamidine synthase

decreases expression

EXP

furan results in decreased expression of PFAS mRNA

NCBI chr10:54,189,157...54,210,685
Ensembl chr10:54,189,157...54,207,272

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

increases expression

EXP

furan results in increased expression of PFKFB1 mRNA

NCBI chr X:22,936,038...22,989,691
Ensembl chr X:22,937,494...22,989,704

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

increases expression

EXP

furan results in increased expression of PFKFB2 mRNA

NCBI chr13:44,683,499...44,727,135
Ensembl chr13:44,699,744...44,726,971

G

profilin 2

increases expression

EXP

furan results in increased expression of PFN2 mRNA

NCBI chr 2:144,217,100...144,222,936
Ensembl chr 2:144,205,636...144,222,936

G

post-GPI attachment to proteins inositol deacylase 1

increases methylation
increases expression

EXP

furan results in increased methylation of PGAP1 gene
furan results in increased expression of PGAP1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 9:63,470,023...63,538,772
Ensembl chr 9:63,470,024...63,538,772

G

post-GPI attachment to proteins GalNAc transferase 4

increases methylation

EXP

furan results in increased methylation of PGAP4 gene

NCBI chr 5:68,727,422...68,742,571
Ensembl chr 5:68,723,625...68,771,167

G

placental growth factor

increases expression
decreases methylation

EXP

furan results in increased expression of PGF mRNA
furan results in decreased methylation of PGF gene

NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747

G

phosphoglycerate kinase 1

affects binding

EXP

furan binds to PGK1 protein

NCBI chr X:75,336,988...75,352,962
Ensembl chr X:75,336,687...75,352,959

G

phosphoglucomutase 2

increases expression

EXP

furan results in increased expression of PGM2 mRNA

NCBI chr14:44,519,906...44,553,420
Ensembl chr14:44,519,906...44,553,770

G

phosphoglucomutase 2-like 1

increases expression

EXP

furan results in increased expression of PGM2L1 mRNA

NCBI chr 1:163,983,917...164,033,027
Ensembl chr 1:163,983,917...164,033,027

G

phosphoglucomutase 3

increases methylation

EXP

furan results in increased methylation of PGM3 gene

NCBI chr 8:96,398,331...96,416,045
Ensembl chr 8:96,398,269...96,416,021

G

prohibitin 2

increases methylation

EXP

furan results in increased methylation of PHB2 gene

NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:159,203,926...159,209,231

G

polyhomeotic homolog 1

increases methylation

EXP

furan results in increased methylation of PHC1 gene

NCBI chr 4:157,182,348...157,205,504
Ensembl chr 4:157,182,348...157,204,709

G

PHD finger protein 11B

decreases methylation

EXP

furan results in decreased methylation of PHF11B gene

NCBI chr15:37,478,888...37,496,535

G

PHD finger protein 20-like 1

decreases expression

EXP

furan results in decreased expression of PHF20L1 mRNA

NCBI chr 7:100,219,598...100,285,580
Ensembl chr 7:100,219,639...100,285,580

G

PHD finger protein 21B

increases methylation
decreases expression

EXP

furan results in increased methylation of PHF21B gene
furan results in decreased expression of PHF21B mRNA

NCBI chr 7:117,793,643...117,864,141
Ensembl chr 7:117,794,046...117,864,141

G

phosphoglycerate dehydrogenase

increases methylation
increases expression

EXP

furan results in increased methylation of PHGDH gene
furan results in increased expression of PHGDH mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789

G

phosphorylase kinase catalytic subunit gamma 1

increases methylation
increases expression

EXP

furan results in increased methylation of PHKG1 gene
furan results in increased expression of PHKG1 mRNA

PMID:22079235 PMID:25539665

NCBI chr12:32,474,926...32,490,657
Ensembl chr12:32,474,921...32,490,653

G

pleckstrin homology-like domain, family A, member 2

increases expression

EXP

furan results in increased expression of PHLDA2 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920

G

pleckstrin homology-like domain, family A, member 3

increases expression

ISO

furan results in increased expression of PHLDA3 mRNA

NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621

G

pleckstrin homology-like domain, family B, member 1

increases expression

EXP

furan results in increased expression of PHLDB1 mRNA

NCBI chr 8:53,900,338...53,948,325
Ensembl chr 8:53,900,338...53,949,518

G

paired-like homeobox 2a

increases methylation

EXP

furan results in increased methylation of PHOX2A gene

NCBI chr 1:165,590,757...165,595,122
Ensembl chr 1:165,590,757...165,595,122

G

putative homeodomain transcription factor 2

increases expression

EXP

furan results in increased expression of PHTF2 mRNA

NCBI chr 4:15,107,341...15,222,683
Ensembl chr 4:15,107,373...15,222,692

G

phytanoyl-CoA dioxygenase domain containing 1

decreases expression

ISO
EXP

furan results in decreased expression of PHYHD1 mRNA

PMID:24183702 PMID:25539665

NCBI chr 3:33,933,487...33,951,614
Ensembl chr 3:33,937,898...33,951,614

G

5-phosphohydroxy-L-lysine phospho-lyase

decreases expression

EXP

furan results in decreased expression of PHYKPL mRNA

NCBI chr10:36,340,905...36,372,555
Ensembl chr10:36,340,945...36,363,721

G

peptidase inhibitor 16

increases expression

EXP

furan results in increased expression of PI16 mRNA

NCBI chr20:7,377,739...7,387,003
Ensembl chr20:7,377,729...7,387,691

G

protein inhibitor of activated STAT, 2

increases methylation

EXP

furan results in increased methylation of PIAS2 gene

NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662

G

phosphotyrosine interaction domain containing 1

decreases expression

EXP

furan results in decreased expression of PID1 mRNA

NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070

G

phosphatidylinositol glycan anchor biosynthesis, class M

decreases expression

EXP

furan results in decreased expression of PIGM mRNA

NCBI chr13:87,370,693...87,374,390
Ensembl chr13:87,368,359...87,376,206

G

phosphatidylinositol glycan anchor biosynthesis, class P

increases expression

ISO

furan results in increased expression of PIGP mRNA

NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082

G

polymeric immunoglobulin receptor

increases methylation
decreases expression

EXP

furan results in increased methylation of PIGR gene
furan results in decreased expression of PIGR mRNA

PMID:22079235 PMID:25539665

NCBI chr13:44,851,001...44,879,143
Ensembl chr13:44,851,182...44,879,141

G

phosphatidylinositol glycan anchor biosynthesis, class V

increases methylation

EXP

furan results in increased methylation of PIGV gene

NCBI chr 5:151,173,486...151,185,748
Ensembl chr 5:151,173,044...151,185,376

G

phosphatidylinositol 3-kinase, catalytic subunit type 3

decreases expression

EXP

furan results in decreased expression of PIK3C3 mRNA

NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539

G

phosphoinositide-3-kinase interacting protein 1

increases methylation
increases expression

EXP

furan results in increased methylation of PIK3IP1 gene
furan results in increased expression of PIK3IP1 mRNA

PMID:22079235 PMID:27387713

NCBI chr14:82,428,315...82,440,261
Ensembl chr14:82,428,248...82,440,260

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

EXP

furan results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

phosphoinositide-3-kinase regulatory subunit 3

increases expression

EXP

furan results in increased expression of PIK3R3 mRNA

NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762

G

phosphoinositide-3-kinase, regulatory subunit 6

increases expression

EXP

furan results in increased expression of PIK3R6 mRNA

NCBI chr10:53,702,821...53,754,113
Ensembl chr10:53,704,682...53,754,497

G

Pim-1 proto-oncogene, serine/threonine kinase

increases methylation

EXP

furan results in increased methylation of PIM1 gene

NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764

G

paired-Ig-like receptor A2

decreases expression

EXP

furan results in decreased expression of PIRA2 mRNA

NCBI chr 1:74,283,713...74,338,208

G

protein kinase domain containing, cytoplasmic

increases expression

EXP

furan results in increased expression of PKDCC mRNA

NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042

G

pyruvate kinase L/R

increases methylation

EXP

furan results in increased methylation of PKLR gene

NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644

G

protein kinase, membrane associated tyrosine/threonine 1

increases methylation
increases expression

EXP

furan results in increased methylation of PKMYT1 gene
furan results in increased expression of PKMYT1 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:13,252,805...13,263,584
Ensembl chr10:13,252,816...13,264,263

G

plakophilin 1

increases methylation
increases expression

EXP

furan results in increased methylation of PKP1 gene
furan results in increased expression of PKP1 mRNA

PMID:22079235 PMID:27387713

NCBI chr13:49,861,340...49,909,162
Ensembl chr13:49,861,340...49,909,162

G

plakophilin 2

increases expression

EXP

furan results in increased expression of PKP2 mRNA

NCBI chr11:98,165,974...98,231,916
Ensembl chr11:98,165,974...98,231,916

G

plakophilin 3

decreases expression

EXP

furan results in decreased expression of PKP3 mRNA

NCBI chr 1:205,617,511...205,628,441
Ensembl chr 1:205,617,511...205,628,440

G

phospholipase A1 member A

increases expression

EXP

furan results in increased expression of PLA1A mRNA

NCBI chr11:75,825,626...75,863,296
Ensembl chr11:75,825,585...75,878,165

G

phospholipase A2, group XIIA

increases expression

EXP

furan results in increased expression of PLA2G12A mRNA

NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964

G

phospholipase A2 group IIA

increases expression

EXP

furan results in increased expression of PLA2G2A mRNA

NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297

G

phospholipase A2, group III

decreases expression

EXP

furan results in decreased expression of PLA2G3 mRNA

NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542

G

phospholipase A2 group VII

increases expression

EXP

furan results in increased expression of PLA2G7 mRNA

PMID:26194646 PMID:27387713

NCBI chr 9:24,859,491...24,901,747
Ensembl chr 9:24,859,502...24,901,747

G

phospholipase A and acyltransferase 1

increases expression

EXP

furan results in increased expression of PLAAT1 mRNA

NCBI chr11:85,022,297...85,041,999
Ensembl chr11:85,022,297...85,031,826

G

phospholipase A and acyltransferase 5

increases expression

EXP

furan results in increased expression of PLAAT5 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:214,276,553...214,307,600
Ensembl chr 1:214,277,044...214,307,598

G

placenta associated 8

increases expression

EXP

furan results in increased expression of PLAC8 mRNA

NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,356,972...9,378,572

G

plasminogen activator, tissue type

increases expression

EXP

furan results in increased expression of PLAT mRNA

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696

G

plasminogen activator, urokinase

increases methylation
increases expression

EXP

furan results in increased methylation of PLAU gene
furan results in increased expression of PLAU mRNA

PMID:22079235 PMID:27387713

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030

G

plasminogen activator, urokinase receptor

increases expression

EXP

furan results in increased expression of PLAUR mRNA

NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130

G

phospholipase B domain containing 2

increases methylation

EXP

furan results in increased methylation of PLBD2 gene

NCBI chr12:41,723,372...41,742,554
Ensembl chr12:41,723,360...41,744,454

G

phospholipase C, beta 2

decreases expression

EXP

furan results in decreased expression of PLCB2 mRNA

NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221

G

phospholipase C, delta 1

increases expression
decreases methylation

EXP

furan results in increased expression of PLCD1 mRNA
furan results in decreased methylation of PLCD1 gene

NCBI chr 8:127,672,955...127,695,939
Ensembl chr 8:127,672,980...127,695,939

G

phospholipase C, delta 3

increases methylation

EXP

furan results in increased methylation of PLCD3 gene

NCBI chr10:88,526,802...88,548,116
Ensembl chr10:88,526,802...88,548,069

G

phospholipase C, delta 4

decreases methylation

EXP

furan results in decreased methylation of PLCD4 gene

NCBI chr 9:83,564,616...83,613,742
Ensembl chr 9:83,564,606...83,606,454

G

phosphatidylinositol-specific phospholipase C, X domain containing 3

increases expression

EXP

furan results in increased expression of PLCXD3 mRNA

NCBI chr 2:55,294,597...55,473,968
Ensembl chr 2:55,294,613...55,474,220

G

phospholipase D1

increases expression

EXP

furan results in increased expression of PLD1 mRNA

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245

G

phospholipase D2

increases expression

EXP

furan results in increased expression of PLD2 mRNA

NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,754,988...55,771,435

G

pleckstrin 2

increases methylation
decreases methylation
increases expression

EXP

furan results in increased methylation of PLEK2 gene
furan results in decreased methylation of PLEK2 gene
furan results in increased expression of PLEK2 mRNA

PMID:22079235 PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 6:103,434,156...103,452,457
Ensembl chr 6:103,434,156...103,452,371

G

pleckstrin homology domain containing A4

increases expression

EXP

furan results in increased expression of PLEKHA4 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:105,142,296...105,165,297
Ensembl chr 1:105,142,348...105,165,297

G

pleckstrin homology domain containing B1

decreases expression

EXP

furan results in decreased expression of PLEKHB1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:164,410,901...164,425,216
Ensembl chr 1:164,410,903...164,428,568

G

pleckstrin homology and FYVE domain containing 1

increases methylation

EXP

furan results in increased methylation of PLEKHF1 gene

NCBI chr 1:100,045,340...100,046,817
Ensembl chr 1:100,027,056...100,053,452

G

pleckstrin homology and FYVE domain containing 2

increases methylation

EXP

furan results in increased methylation of PLEKHF2 gene

NCBI chr 5:28,888,358...28,905,350
Ensembl chr 5:28,868,469...28,923,514

G

pleckstrin homology and RhoGEF domain containing G2

increases expression

EXP

furan results in increased expression of PLEKHG2 mRNA

NCBI chr 1:92,779,449...92,792,610
Ensembl chr 1:92,779,449...92,792,610

G

pleckstrin homology and RhoGEF domain containing G5

decreases expression

ISO
EXP

furan results in decreased expression of PLEKHG5 mRNA

PMID:24183702 PMID:25539665

NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229

G

pleckstrin homology, MyTH4 and FERM domain containing H3

increases methylation

EXP

furan results in increased methylation of PLEKHH3 gene

NCBI chr10:86,598,749...86,607,482
Ensembl chr10:86,598,754...86,607,165

G

plasminogen

decreases expression

EXP

furan results in decreased expression of PLG mRNA

NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320

G

plasminogen receptor with a C-terminal lysine

increases expression

EXP

furan results in increased expression of PLGRKT mRNA

NCBI chr 1:236,512,574...236,526,858
Ensembl chr 1:236,512,580...236,524,840

G

polo-like kinase 1

increases expression

EXP

furan results in increased expression of PLK1 mRNA

NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637

G

polo-like kinase 4

increases expression

EXP

furan results in increased expression of PLK4 mRNA

NCBI chr 2:125,730,480...125,748,894
Ensembl chr 2:125,730,460...125,748,892

G

plasmolipin

increases expression

EXP

furan results in increased expression of PLLP mRNA

NCBI chr19:10,321,080...10,341,869
Ensembl chr19:10,321,080...10,342,226

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

decreases methylation
increases expression

EXP

furan results in decreased methylation of PLOD2 gene
furan results in increased expression of PLOD2 mRNA

NCBI chr 8:101,964,318...102,047,022
Ensembl chr 8:101,964,318...102,047,022

G

proteolipid protein 2

increases expression

EXP

furan results in increased expression of PLP2 mRNA

NCBI chr X:17,506,153...17,509,552
Ensembl chr X:17,506,059...17,509,550

G

phospholipid phosphatase 1

decreases methylation

EXP

furan results in decreased methylation of PPAP2A gene

NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676

G

phospholipid phosphatase 3

decreases expression

EXP

furan results in decreased expression of PLPP3 mRNA

NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667

G

phospholipid phosphatase 6

increases methylation

EXP

furan results in increased methylation of PLPP6 gene

NCBI chr 1:236,092,642...236,095,494
Ensembl chr 1:236,090,364...236,101,554

G

phospholipid phosphatase related 1

decreases expression

EXP

furan results in decreased expression of LPPR1 mRNA

NCBI chr 5:68,232,963...68,520,784
Ensembl chr 5:68,232,963...68,592,444

G

phospholipid phosphatase related 3

increases expression
decreases methylation

EXP

furan results in increased expression of PLPPR3 mRNA
furan results in decreased methylation of PLPPR3 gene

NCBI chr 7:10,481,624...10,493,059
Ensembl chr 7:10,481,636...10,495,921

G

pleiotropic regulator 1

increases methylation

EXP

furan results in increased methylation of PLRG1 gene

NCBI chr 2:170,706,188...170,722,519
Ensembl chr 2:170,706,173...170,722,573

G

phospholipid scramblase 1

increases expression

EXP

furan results in increased expression of PLSCR1 mRNA

NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:101,664,056...101,684,614

G

plasmalemma vesicle associated protein

increases expression

EXP

furan results in increased expression of PLVAP mRNA

NCBI chr16:18,218,966...18,231,279
Ensembl chr16:18,218,967...18,231,454

G

plexin domain containing 1

increases expression

EXP

furan results in increased expression of PLXDC1 mRNA

NCBI chr10:83,418,837...83,478,451
Ensembl chr10:83,418,837...83,478,755

G

plexin domain containing 2

increases expression

EXP

furan results in increased expression of PLXDC2 mRNA

NCBI chr17:84,077,793...84,502,831
Ensembl chr17:84,104,864...84,497,999

G

plexin A2

decreases expression

EXP

furan results in decreased expression of PLXNA2 mRNA

NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453

G

plexin B1

increases expression

ISO

furan results in increased expression of PLXNB1 mRNA

NCBI chr 8:118,621,961...118,647,491
Ensembl chr 8:118,623,040...118,647,489

G

peptidase M20 domain containing 1

increases methylation

EXP

furan results in increased methylation of PM20D1 gene

NCBI chr13:45,790,161...45,812,206
Ensembl chr13:45,790,179...45,812,206

G

phorbol-12-myristate-13-acetate-induced protein 1

increases methylation

EXP

furan results in increased methylation of PMAIP1 gene

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382

G

prostate transmembrane protein, androgen induced 1

increases methylation
increases expression

EXP

furan results in increased methylation of PMEPA1 gene
furan results in increased expression of PMEPA1 mRNA

PMID:22079235 PMID:27387713

NCBI chr 3:182,430,193...182,478,649
Ensembl chr 3:182,430,193...182,478,649

G

peripheral myelin protein 22

increases expression

EXP

furan results in increased expression of PMP22 mRNA

PMID:22079235 PMID:27387713

NCBI chr10:48,294,932...48,324,941
Ensembl chr10:48,297,437...48,324,940

G

PMS1 homolog 1, mismatch repair system component

increases expression

EXP

furan results in increased expression of PMS1 mRNA

NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221

G

PMS1 homolog 2, mismatch repair system component

increases expression

EXP

furan results in increased expression of PMS2 mRNA

NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248

G

purine nucleoside phosphorylase

increases expression

ISO

furan results in increased expression of PNP2 mRNA

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162

G

patatin-like phospholipase domain containing 1

increases expression

EXP

furan results in increased expression of PNPLA1 mRNA

NCBI chr20:6,919,689...6,953,850
Ensembl chr20:6,919,115...6,955,143

G

patatin-like phospholipase domain containing 3

increases expression

ISO

furan results in increased expression of PNPLA3 mRNA

NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594

G

patatin-like phospholipase domain containing 7

decreases expression

EXP

furan results in decreased expression of PNPLA7 mRNA

NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672

G

proline-rich nuclear receptor coactivator 2

increases methylation

EXP

furan results in increased methylation of PNRC2 gene

NCBI chr 5:153,387,522...153,390,506
Ensembl chr 5:153,378,863...153,390,748

G

podocalyxin-like 2

increases expression

EXP

furan results in increased expression of PODXL2 mRNA

NCBI chr 4:122,863,476...122,895,318
Ensembl chr 4:122,863,477...122,895,360

G

POF1B, actin binding protein

increases expression

EXP

furan results in increased expression of POF1B mRNA

NCBI chr X:81,875,348...81,942,046
Ensembl chr X:81,875,348...81,941,906

G

pogo transposable element derived with KRAB domain

decreases expression

EXP

furan results in decreased expression of POGK mRNA

NCBI chr13:81,180,410...81,196,326
Ensembl chr13:81,180,410...81,196,326

G

DNA polymerase delta 1, catalytic subunit

increases expression

EXP

furan results in increased expression of POLD1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 1:104,161,984...104,178,074
Ensembl chr 1:104,162,016...104,172,982

G

DNA polymerase delta 2, accessory subunit

increases methylation
increases expression

EXP

furan results in increased methylation of POLD2 gene
furan results in increased expression of POLD2 mRNA

PMID:22079235 PMID:25539665

NCBI chr14:84,962,933...84,969,148
Ensembl chr14:84,962,022...84,967,874

G

DNA polymerase delta interacting protein 2

decreases methylation

EXP

furan results in decreased methylation of POLDIP2 gene

NCBI chr10:63,905,287...63,915,655
Ensembl chr10:63,904,691...63,915,655

G

DNA polymerase epsilon, catalytic subunit

increases expression

EXP
ISO

furan results in increased expression of POLE mRNA

PMID:20194422 PMID:22079235

NCBI chr12:52,005,155...52,053,761
Ensembl chr12:52,005,155...52,053,662

G

DNA polymerase epsilon 2, accessory subunit

increases expression

EXP

furan results in increased expression of POLE2 mRNA

NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:93,410,758...93,435,361

G

DNA polymerase gamma, catalytic subunit

increases methylation

EXP

furan results in increased methylation of POLG gene

NCBI chr 1:142,792,119...142,808,933
Ensembl chr 1:142,792,119...142,808,838

G

DNA polymerase iota

increases expression

EXP

furan results in increased expression of POLI mRNA

NCBI chr18:66,389,214...66,409,734
Ensembl chr18:66,364,236...66,409,819

G

DNA polymerase kappa

increases expression

ISO

furan results in increased expression of POLK mRNA

NCBI chr 2:29,556,831...29,616,960
Ensembl chr 2:29,557,336...29,616,960

G

RNA polymerase I and III subunit D

increases methylation

EXP

furan results in increased methylation of POLR1D gene

NCBI chr12:13,084,505...13,118,069
Ensembl chr12:13,084,512...13,095,627

G

RNA polymerase III subunit G

increases expression
increases methylation

EXP

furan results in increased expression of POLR3G mRNA
furan results in increased methylation of POLR3G gene

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr 2:13,680,893...13,721,802
Ensembl chr 2:13,680,895...13,721,802

G

RNA polymerase III subunit H

increases methylation

EXP

furan results in increased methylation of POLR3H gene

NCBI chr 7:115,309,571...115,319,881
Ensembl chr 7:115,309,589...115,319,915

G

paraoxonase 1

decreases expression

EXP

furan results in decreased expression of PON1 mRNA

NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924

G

POP1 homolog, ribonuclease P/MRP subunit

increases expression

EXP

furan results in increased expression of POP1 mRNA

NCBI chr 7:67,590,502...67,618,187
Ensembl chr 7:67,590,522...67,618,293

G

popeye domain cAMP effector 1

increases methylation

EXP

furan results in increased methylation of POPDC1 gene

NCBI chr20:50,401,611...50,442,653
Ensembl chr20:50,401,733...50,442,645

G

popeye domain cAMP effector 2

increases expression

EXP

furan results in increased expression of POPDC2 mRNA

NCBI chr11:75,850,068...75,897,094
Ensembl chr11:75,880,274...75,896,269

G

cytochrome p450 oxidoreductase

increases expression

EXP

furan results in increased expression of POR mRNA

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809

G

periostin

increases expression

EXP

furan results in increased expression of POSTN mRNA

NCBI chr 2:140,677,774...140,709,304
Ensembl chr 2:140,677,754...140,709,300

G

POU class 2 homeobox associating factor 1

decreases expression
increases expression

EXP

furan results in decreased expression of POU2AF1 mRNA
furan results in increased expression of POU2AF1 mRNA

PMID:25539665 PMID:27387713

NCBI chr 8:60,418,173...60,445,176
Ensembl chr 8:60,436,844...60,445,176

G

inorganic pyrophosphatase 1

affects binding

EXP

furan binds to PPA1 protein

NCBI chr20:30,132,088...30,160,492
Ensembl chr20:30,133,504...30,160,489

G

inorganic pyrophosphatase 2

increases methylation

EXP

furan results in increased methylation of PPA2 gene

NCBI chr 2:224,472,738...224,552,101
Ensembl chr 2:224,474,823...224,552,628

G

peroxisome proliferator activated receptor alpha

increases expression

EXP

furan results in increased expression of PPARA mRNA

NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714

G

peroxisome proliferator-activated receptor delta

increases methylation
decreases expression

EXP

furan results in increased methylation of PPARD gene
furan results in decreased expression of PPARD mRNA

PMID:22079235 PMID:26194646

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707

G

peroxisome proliferator-activated receptor gamma

decreases expression

EXP

furan results in decreased expression of PPARG mRNA

PMID:25539665 PMID:26194646

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

phosphopantothenoylcysteine synthetase

increases methylation

EXP

furan results in increased methylation of PPCS gene

NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012

G

PTPRF interacting protein alpha 2

increases expression

EXP

furan results in increased expression of PPFIA2 mRNA

NCBI chr 7:43,652,258...44,126,555
Ensembl chr 7:43,653,053...44,126,557

G

peptidylprolyl isomerase C

increases expression

EXP

furan results in increased expression of PPIC mRNA

PMID:26194646 PMID:27387713

NCBI chr18:49,040,690...49,053,296
Ensembl chr18:49,040,692...49,053,466

G

periplakin

increases expression
decreases methylation

ISO
EXP

furan results in increased expression of PPL mRNA
furan results in decreased methylation of PPL gene

PMID:24183702 PMID:25539665 PMID:27387713

NCBI chr10:10,957,388...11,003,035
Ensembl chr10:10,957,341...11,003,658

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

increases expression

EXP

furan results in increased expression of PPM1D mRNA

NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256

G

protein phosphatase, Mg2+/Mn2+ dependent, 1J

increases expression

EXP

furan results in increased expression of PPM1J mRNA

NCBI chr 2:194,966,854...194,972,228
Ensembl chr 2:194,966,950...194,972,227

G

protein phosphatase, Mg2+/Mn2+ dependent 1N

increases expression

EXP

furan results in increased expression of PPM1N mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:88,057,365...88,062,912
Ensembl chr 1:88,058,624...88,060,700

G

protein phosphatase 1, regulatory subunit 10

increases expression

ISO

furan results in increased expression of PPP1R10 mRNA

NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418

G

protein phosphatase 1, regulatory inhibitor subunit 14B like

increases methylation

EXP

furan results in increased methylation of PPP1R14BL gene

NCBI chr 9:33,027,512...33,029,145
Ensembl chr 9:33,026,706...33,029,403

G

protein phosphatase 1, regulatory (inhibitor) subunit 14D

increases expression

EXP

furan results in increased expression of PPP1R14D mRNA

NCBI chr 3:126,658,886...126,673,132
Ensembl chr 3:126,658,886...126,673,132

G

protein phosphatase 1, regulatory subunit 15A

decreases expression

EXP

furan results in decreased expression of PPP1R15A mRNA

NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774

G

protein phosphatase 1, regulatory (inhibitor) subunit 1A

increases expression

EXP

furan results in increased expression of PPP1R1A mRNA

NCBI chr 7:136,533,031...136,540,687
Ensembl chr 7:136,523,604...136,540,683

G

protein phosphatase 1, regulatory (inhibitor) subunit 1B

increases expression
decreases methylation

ISO
EXP

furan results in increased expression of PPP1R1B mRNA
furan results in decreased methylation of PPP1R1B gene

PMID:24183702 PMID:27387713

NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,844,036...83,853,063

G

protein phosphatase 1, regulatory subunit 27

increases methylation

EXP

furan results in increased methylation of PPP1R27 gene

NCBI chr10:106,326,691...106,327,860
Ensembl chr10:106,326,691...106,327,860

G

protein phosphatase 1, regulatory subunit 3B

increases methylation
decreases expression

EXP

furan results in increased methylation of PPP1R3B gene
furan results in decreased expression of PPP1R3B mRNA

PMID:22079235 PMID:25539665

NCBI chr16:63,533,318...63,545,683
Ensembl chr16:63,532,842...63,549,997

G

protein phosphatase 1, regulatory subunit 3C

increases methylation

EXP

furan results in increased methylation of PPP1R3C gene

NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835

G

protein phosphatase 1, regulatory subunit 3D

decreases methylation

EXP

furan results in decreased methylation of PPP1R3D gene

NCBI chr 3:185,880,087...185,883,158
Ensembl chr 3:185,876,709...185,883,703

G

protein phosphatase 1, regulatory subunit 3G

decreases expression

ISO
EXP

furan results in decreased expression of PPP1R3G mRNA

PMID:24183702 PMID:26194646

NCBI chr17:29,080,407...29,083,739
Ensembl chr17:29,070,658...29,085,135

G

protein phosphatase 1, regulatory subunit 42

increases expression

EXP

furan results in increased expression of PPP1R42 mRNA

NCBI chr 5:14,009,972...14,057,330
Ensembl chr 5:14,010,036...14,057,345

G

protein phosphatase 2, regulatory subunit B'', alpha

decreases expression

EXP

furan results in decreased expression of PPP2R3A mRNA

NCBI chr 8:110,582,479...110,720,516
Ensembl chr 8:110,583,743...110,677,482

G

protein phosphatase 3 catalytic subunit alpha

increases expression

EXP

furan results in increased expression of PPP3CA mRNA

NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554

G

protein phosphatase 3, regulatory subunit B, beta

increases methylation
decreases expression

EXP

furan results in increased methylation of PPP3R2 gene
furan results in decreased expression of PPP3R2 mRNA

PMID:22079235 PMID:27387713

NCBI chr 5:68,822,387...68,823,382
Ensembl chr 5:68,822,387...68,823,818

G

palmitoyl-protein thioesterase 1

increases methylation

EXP

furan results in increased methylation of PPT1 gene

NCBI chr 5:140,406,318...140,427,201
Ensembl chr 5:140,406,214...140,427,200

G

PEAK1 related kinase activating pseudokinase 1

increases expression

EXP

furan results in increased expression of PRAG1 mRNA

NCBI chr16:62,791,249...62,844,532
Ensembl chr16:62,786,329...62,844,532

G

proline-rich acidic protein 1

increases expression

EXP

furan results in increased expression of PRAP1 mRNA

NCBI chr 1:204,312,723...204,316,519
Ensembl chr 1:204,312,723...204,316,517

G

protein regulator of cytokinesis 1

increases expression

EXP

furan results in increased expression of PRC1 mRNA

NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012

G

prolylcarboxypeptidase

increases expression

EXP

furan results in increased expression of PRCP mRNA

NCBI chr 1:156,343,894...156,396,295
Ensembl chr 1:156,343,896...156,396,939

G

PR/SET domain 2

decreases expression

EXP

furan results in decreased expression of PRDM2 mRNA

NCBI chr 5:160,704,396...160,815,184
Ensembl chr 5:160,705,462...160,815,140

G

peroxiredoxin 1

increases expression
increases methylation
affects binding

EXP

furan results in increased expression of PRDX1 mRNA
furan results in increased methylation of PRDX1 gene
furan binds to PRDX1 protein

PMID:15120968 PMID:22079235 PMID:22240984

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

peroxiredoxin 3

increases methylation

EXP

furan results in increased methylation of PRDX3 gene

NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300

G

peroxiredoxin 4

increases methylation

EXP

furan results in increased methylation of PRDX4 gene

NCBI chr X:43,876,374...43,893,815
Ensembl chr X:43,876,417...43,893,812

G

proline and arginine rich end leucine rich repeat protein

increases expression

EXP

furan results in increased expression of PRELP mRNA

NCBI chr13:47,920,480...47,943,547
Ensembl chr13:47,922,590...47,932,324

G

prolyl endopeptidase

increases methylation

EXP

furan results in increased methylation of PREP gene

NCBI chr20:50,138,588...50,235,549
Ensembl chr20:50,131,819...50,252,697

G

prolyl endopeptidase-like

increases methylation

EXP

furan results in increased methylation of PREPL gene

NCBI chr 6:15,333,107...15,362,825
Ensembl chr 6:15,333,077...15,363,231

G

proteoglycan 4

decreases expression

EXP

furan results in decreased expression of PRG4 mRNA

NCBI chr13:65,037,363...65,054,764
Ensembl chr13:65,037,363...65,054,508

G

prickle planar cell polarity protein 2

increases methylation

EXP

furan results in increased methylation of PRICKLE2 gene

NCBI chr 4:126,426,767...126,771,986
Ensembl chr 4:126,426,771...126,772,008

G

protein kinase AMP-activated catalytic subunit alpha 1

increases expression

EXP

furan results in increased expression of PRKAA1 mRNA

NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450

G

protein kinase AMP-activated non-catalytic subunit beta 1

increases methylation

EXP

furan results in increased methylation of PRKAB1 gene

NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482

G

protein kinase cAMP-dependent type II regulatory subunit beta

increases expression

EXP

furan results in increased expression of PRKAR2B mRNA

NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411

G

protein kinase C, beta

decreases expression
increases methylation

EXP

furan results in decreased expression of PRKCB mRNA
furan results in increased methylation of PRKCB gene

PMID:15120968 PMID:22079235

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740

G

protein kinase, DNA-activated, catalytic subunit

decreases expression

EXP

furan results in decreased expression of PRKDC mRNA

NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108

G

parkin RBR E3 ubiquitin protein ligase

increases methylation

EXP

furan results in increased methylation of PRKN gene

NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304

G

prolactin

decreases expression
multiple interactions

EXP

furan results in decreased expression of PRL protein
protocatechuic acid inhibits the reaction [furan results in decreased expression of PRL protein]

NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217

G

prolactin receptor

increases expression

EXP

furan results in increased expression of PRLR mRNA

PMID:20562052 PMID:25539665 PMID:26194646

NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882

G

protein arginine methyltransferase 2

increases expression

EXP

furan results in increased expression of PRMT2 mRNA

NCBI chr20:12,391,388...12,420,096
Ensembl chr20:12,394,268...12,420,108

G

prion protein

increases expression

EXP

furan results in increased expression of PRNP mRNA

NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:139,630,144...139,658,436

G

protein C, inactivator of coagulation factors Va and VIIIa

decreases expression

EXP

furan results in decreased expression of PROC mRNA

NCBI chr18:24,038,596...24,049,061
Ensembl chr18:24,038,597...24,048,964

G

protein C receptor

increases expression

EXP

furan results in increased expression of PROCR mRNA

NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989

G

proline dehydrogenase 1

decreases expression

EXP

furan results in decreased expression of PRODH mRNA

PMID:25539665 PMID:26194646

NCBI chr11:96,414,275...96,431,604
Ensembl chr11:96,414,224...96,433,418

G

prominin 1

increases expression

ISO
EXP

furan results in increased expression of PROM1 mRNA

PMID:24183702 PMID:26194646 PMID:38160780

NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002

G

prominin 2

increases expression

ISO

furan results in increased expression of PROM2 mRNA

NCBI chr 3:135,200,944...135,215,130
Ensembl chr 3:135,200,944...135,215,077

G

protein only RNase P catalytic subunit

increases methylation

EXP

furan results in increased methylation of PRORP gene

NCBI chr 6:78,404,821...78,497,562
Ensembl chr 6:78,405,980...78,497,761

G

protein Z, vitamin K-dependent plasma glycoprotein

increases methylation

EXP

furan results in increased methylation of PROZ gene

NCBI chr16:83,150,104...83,165,688
Ensembl chr16:83,152,152...83,165,619

G

proline rich 32

increases expression

EXP

furan results in increased expression of PRR32 mRNA

NCBI chr X:128,856,085...128,858,003
Ensembl chr X:128,856,069...128,857,999

G

proline-rich coiled-coil 1

increases methylation

EXP

furan results in increased methylation of PRRC1 gene

NCBI chr18:53,010,606...53,047,601
Ensembl chr18:53,010,600...53,045,015

G

proline-rich transmembrane protein 1

increases expression

EXP

furan results in increased expression of PRRT1 mRNA

NCBI chr20:4,122,565...4,126,386
Ensembl chr20:4,122,508...4,126,213

G

proline-rich transmembrane protein 4

increases methylation

EXP

furan results in increased methylation of PRRT4 gene

NCBI chr 4:58,731,447...58,742,408
Ensembl chr 4:58,730,947...58,740,689

G

paired related homeobox 1

increases expression

EXP

furan results in increased expression of PRRX1 mRNA

NCBI chr13:78,136,783...78,205,379
Ensembl chr13:78,136,783...78,204,058

G

paired related homeobox 2

increases expression

EXP

furan results in increased expression of PRRX2 mRNA

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:34,520,173...34,566,284

G

serine protease 22

increases expression

EXP

furan results in increased expression of PRSS22 mRNA

NCBI chr10:13,533,725...13,538,435
Ensembl chr10:13,533,725...13,538,435

G

serine protease 27

increases methylation
decreases expression

EXP

furan results in increased methylation of PRSS27 gene
furan results in decreased expression of PRSS27 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:13,574,526...13,581,887
Ensembl chr10:13,574,526...13,581,887

G

protease, serine, 30

increases expression

EXP

furan results in increased expression of PRSS30 mRNA

NCBI chr10:13,511,916...13,519,968
Ensembl chr10:13,511,916...13,515,605

G

phosphoribosyl transferase domain containing 1

increases expression

EXP

furan results in increased expression of PRTFDC1 mRNA

NCBI chr17:88,457,872...88,563,109
Ensembl chr17:88,457,872...88,563,066

G

protogenin

decreases expression

EXP

furan results in decreased expression of PRTG mRNA

PMID:25539665 PMID:26194646

NCBI chr 8:82,429,106...82,538,612
Ensembl chr 8:82,429,132...82,538,602

G

peroxiredoxin like 2A

increases methylation

EXP

furan results in increased methylation of PRXL2A gene

NCBI chr16:16,900,697...16,920,521
Ensembl chr16:16,900,699...16,920,561

G

phosphoserine aminotransferase 1

increases expression

EXP

furan results in increased expression of PSAT1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693

G

pregnancy specific glycoprotein 19

decreases expression

EXP

furan results in decreased expression of PSG19 mRNA

NCBI chr 1:87,549,234...87,559,500
Ensembl chr 1:87,549,234...87,559,500

G

proteasome 20S subunit alpha 7

increases methylation

EXP

furan results in increased methylation of PSMA7 gene

NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253

G

proteasome 20S subunit alpha 8

decreases expression

EXP

furan results in decreased expression of PSMA8 mRNA

NCBI chr18:6,138,226...6,202,802
Ensembl chr18:6,138,226...6,202,802

G

proteasome subunit beta 11

increases methylation

EXP

furan results in increased methylation of PSMB11 gene

NCBI chr15:32,054,747...32,055,666
Ensembl chr15:32,049,118...32,056,299

G

proteasome 20S subunit beta 5

increases methylation

EXP

furan results in increased methylation of PSMB5 gene

NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379

G

proteasome 26S subunit, non-ATPase 14

increases methylation

EXP

furan results in increased methylation of PSMD14 gene

NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:66,662,900...66,755,665

G

proteasome 26S subunit, non-ATPase 5

increases methylation

EXP

furan results in increased methylation of PSMD5 gene

NCBI chr 3:38,531,206...38,552,085
Ensembl chr 3:38,530,951...38,548,490

G

proteasome assembly chaperone 1

increases methylation

EXP

furan results in increased methylation of PSMG1 gene

NCBI chr11:48,745,581...48,755,040
Ensembl chr11:48,745,581...48,755,040

G

proteasome assembly chaperone 4

increases expression

EXP

furan results in increased expression of PSMG4 mRNA

NCBI chr17:30,916,031...30,923,430
Ensembl chr17:30,916,031...30,923,612

G

polypyrimidine tract binding protein 2

increases expression

EXP

furan results in increased expression of PTBP2 mRNA

NCBI chr 2:210,497,610...210,558,497
Ensembl chr 2:210,497,706...210,558,291

G

prostaglandin D2 receptor 2

decreases expression

EXP

furan results in decreased expression of PTGDR2 mRNA

NCBI chr 1:217,010,183...217,015,044
Ensembl chr 1:216,995,629...217,022,393

G

prostaglandin F receptor

increases methylation

EXP

furan results in increased methylation of PTGFR gene

NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:243,393,350...243,425,623

G

prostaglandin I2 synthase

increases expression

EXP

furan results in increased expression of PTGIS mRNA

NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650

G

prostaglandin reductase 1

increases expression

EXP

furan results in increased expression of PTGR1 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811

G

prostaglandin-endoperoxide synthase 1

decreases expression

EXP

furan results in decreased expression of PTGS1 mRNA

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

protein tyrosine kinase 2 beta

decreases expression
increases expression

ISO
EXP

furan results in decreased expression of PTK2B mRNA
furan results in increased expression of PTK2B mRNA

PMID:24183702 PMID:25539665

NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806

G

protein tyrosine kinase 6

decreases expression

EXP

furan results in decreased expression of PTK6 mRNA

PMID:25539665 PMID:26194646

NCBI chr 3:188,684,633...188,693,224
Ensembl chr 3:188,684,633...188,693,224

G

protein tyrosine kinase 7

increases expression

EXP

furan results in increased expression of PTK7 mRNA

NCBI chr 9:21,849,756...21,916,077
Ensembl chr 9:21,849,801...21,916,078

G

parathymosin

increases methylation

EXP

furan results in increased methylation of PTMS gene

NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212

G

pleiotrophin

increases expression

EXP

furan results in increased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482

G

protein tyrosine phosphatase 4A1

increases methylation
increases expression

EXP

furan results in increased methylation of PTP4A1 gene
furan results in increased expression of PTP4A1 mRNA

PMID:22079235 PMID:26194646

NCBI chr 9:40,710,250...40,718,176
Ensembl chr 9:40,710,250...40,718,176

G

protein phosphatase 2 phosphatase activator

increases methylation

EXP

furan results in increased methylation of PTPA gene

NCBI chr 3:34,087,637...34,118,100
Ensembl chr 3:34,087,575...34,162,772

G

protein tyrosine phosphatase, non-receptor type 13

increases expression

EXP

furan results in increased expression of PTPN13 mRNA

PMID:25539665 PMID:26194646 PMID:27387713

NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,412,841...6,587,171

G

protein tyrosine phosphatase, receptor type, C

increases expression

EXP

furan results in increased expression of PTPRC mRNA

NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746

G

protein tyrosine phosphatase, receptor type, D

decreases expression

EXP

furan results in decreased expression of PTPRD mRNA

NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903

G

protein tyrosine phosphatase, receptor type, N

increases expression

EXP

furan results in increased expression of PTPRN mRNA

NCBI chr 9:84,189,676...84,205,364
Ensembl chr 9:84,189,676...84,204,850

G

protein tyrosine phosphatase, receptor type, O

increases methylation
increases expression

EXP

furan results in increased methylation of PTPRO gene
furan results in increased expression of PTPRO mRNA

PMID:22079235 PMID:27387713

NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903

G

protein tyrosine phosphatase, receptor type Z1

increases methylation
increases expression
decreases methylation

EXP

furan results in increased methylation of PTPRZ1 gene
furan results in increased expression of PTPRZ1 mRNA
furan results in decreased methylation of PTPRZ1 gene

PMID:22079235 PMID:27387713

NCBI chr 4:52,363,006...52,560,905
Ensembl chr 4:52,363,295...52,560,903

G

PTTG1 regulator of sister chromatid separation, securin

increases expression

EXP

furan results in increased expression of PTTG1 mRNA

PMID:22079235 PMID:25539665

NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309

G

pentraxin 3

increases expression

EXP

furan results in increased expression of PTX3 mRNA

NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372

G

PVR cell adhesion molecule

increases expression

EXP

furan results in increased expression of PVR mRNA

NCBI chr 1:88,689,235...88,704,641
Ensembl chr 1:88,688,981...88,704,630

G

PWWP domain containing 3B

increases methylation

EXP

furan results in increased methylation of PWWP3B gene

NCBI chr X:107,593,062...107,627,215
Ensembl chr X:107,582,676...107,627,803

G

peroxidasin

increases expression

EXP

furan results in increased expression of PXDN mRNA

NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942

G

PYD and CARD domain containing

increases expression
multiple interactions

EXP
ISO

furan results in increased expression of PYCARD mRNA
furan results in increased expression of PYCARD protein
rhodioloside inhibits the reaction [furan results in increased expression of PYCARD protein]

PMID:22079235 PMID:34450210

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

pyrroline-5-carboxylate reductase 1

increases methylation
increases expression

EXP

furan results in increased methylation of PYCR1 gene
furan results in increased expression of PYCR1 mRNA

PMID:22079235 PMID:26194646

NCBI chr10:106,416,056...106,420,982
Ensembl chr10:106,412,576...106,423,393

G

glycogen phosphorylase B

increases expression

EXP

furan results in increased expression of PYGB mRNA

NCBI chr 3:160,072,141...160,118,930
Ensembl chr 3:160,072,115...160,123,961

G

quinolinate phosphoribosyltransferase

increases methylation

EXP

furan results in increased methylation of QPRT gene

NCBI chr 1:191,148,715...191,164,006
Ensembl chr 1:191,148,713...191,194,162

G

glutamine and serine rich 1

decreases expression

EXP

furan results in decreased expression of QSER1 mRNA

NCBI chr 3:111,592,377...111,658,825
Ensembl chr 3:111,595,171...111,657,103

G

R3H domain containing 2

decreases expression

EXP

furan results in decreased expression of R3HDM2 mRNA

NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862

G

RAB12, member RAS oncogene family

increases methylation

EXP

furan results in increased methylation of RAB12 gene

NCBI chr 9:113,927,119...113,953,722
Ensembl chr 9:113,927,119...113,953,695

G

RAB15, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB15 mRNA

NCBI chr 6:101,232,740...101,257,388
Ensembl chr 6:101,232,743...101,257,083

G

RAB19, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB19 mRNA

NCBI chr 4:69,123,962...69,133,691
Ensembl chr 4:69,123,924...69,134,383

G

RAB1B, member RAS oncogene family

increases methylation

EXP

furan results in increased methylation of RAB1B gene

NCBI chr 1:211,835,133...211,843,408
Ensembl chr 1:211,835,073...211,843,337
Ensembl chr X:211,835,073...211,843,337

G

RAB20, member RAS oncogene family

increases methylation

EXP

furan results in increased methylation of RAB20 gene

NCBI chr16:84,721,427...84,745,610
Ensembl chr16:84,721,427...84,745,610

G

RAB25, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB25 mRNA

PMID:27387713 PMID:38160780

NCBI chr 2:176,298,124...176,304,221
Ensembl chr 2:176,298,124...176,304,221

G

RAB26, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB26 mRNA

NCBI chr10:14,057,942...14,062,602
Ensembl chr10:14,057,942...14,062,577

G

RAB30, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB30 mRNA

NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778

G

RAB31, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB31 mRNA

NCBI chr 9:112,693,596...112,828,104
Ensembl chr 9:112,693,597...112,828,092

G

RAB32, member RAS oncogene family

increases methylation

EXP

furan results in increased methylation of RAB32 gene

NCBI chr 1:6,766,448...6,781,258
Ensembl chr 1:6,766,455...6,781,258

G

RAB35, member RAS oncogene family

increases methylation

EXP

furan results in increased methylation of RAB35 gene

NCBI chr12:46,627,302...46,642,815
Ensembl chr12:46,627,864...46,645,426

G

RAB3A, member RAS oncogene family

decreases expression

ISO

furan results in decreased expression of RAB3A mRNA

NCBI chr16:18,718,164...18,722,273
Ensembl chr16:18,718,167...18,721,842

G

RAB3D, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB3D mRNA

NCBI chr 8:28,714,706...28,725,379
Ensembl chr 8:28,716,241...28,725,317

G

RAB3 GTPase activating non-catalytic protein subunit 2

increases methylation

EXP

furan results in increased methylation of RAB3GAP2 gene

NCBI chr13:99,288,984...99,362,817
Ensembl chr13:99,288,647...99,361,053

G

RAB6B, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAB6B mRNA

NCBI chr 8:112,574,223...112,642,911
Ensembl chr 8:112,574,167...112,642,907

G

rabaptin, RAB GTPase binding effector protein 1

decreases expression

EXP

furan results in decreased expression of RABEP1 mRNA

NCBI chr10:56,064,742...56,168,778
Ensembl chr10:56,064,753...56,166,177

G

RAB GTPase activating protein 1

increases methylation

EXP

furan results in increased methylation of RABGAP1 gene

NCBI chr 3:41,617,784...41,735,795
Ensembl chr 3:41,617,793...41,735,791

G

Rab geranylgeranyltransferase subunit alpha

increases methylation

EXP

furan results in increased methylation of RABGGTA gene

NCBI chr15:33,176,268...33,183,320
Ensembl chr15:33,176,099...33,183,271

G

RAB, member RAS oncogene family-like 6

increases methylation

EXP

furan results in increased methylation of RABL6 gene

NCBI chr 3:28,800,802...28,826,722
Ensembl chr 3:28,800,802...28,826,722

G

Rac GTPase-activating protein 1

increases expression

EXP

furan results in increased expression of RACGAP1 mRNA

NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738

G

receptor for activated C kinase 1

increases expression

EXP

furan results in increased expression of RACK1 mRNA

PMID:25539665 PMID:26194646

NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948

G

RAD17 checkpoint clamp loader component

increases expression

EXP

furan results in increased expression of RAD17 mRNA

NCBI chr 2:33,498,335...33,528,614
Ensembl chr 2:33,498,336...33,528,144

G

RAD18 E3 ubiquitin protein ligase

increases expression

EXP

furan results in increased expression of RAD18 mRNA

NCBI chr 4:147,291,463...147,376,904
Ensembl chr 4:147,291,276...147,376,869

G

RAD51 recombinase

decreases expression
increases expression

EXP

furan results in decreased expression of RAD51 mRNA
furan results in increased expression of RAD51 mRNA

PMID:22507866 PMID:25539665

NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469

G

RAD51 associated protein 1

increases expression

EXP

furan results in increased expression of RAD51AP1 mRNA

NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:161,445,512...161,458,680

G

RAD51 paralog B

increases expression
decreases expression

ISO

furan results in increased expression of RAD51B mRNA
furan results in decreased expression of RAD51B mRNA

PMID:20194422 PMID:24183702

NCBI chr 6:103,829,390...104,373,923
Ensembl chr 6:103,829,554...104,374,509

G

RAD51 paralog C

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of RAD51C gene
furan results in increased expression of RAD51C mRNA

PMID:20194422 PMID:22079235

NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143

G

RAD52 homolog, DNA repair protein

decreases expression

EXP

furan results in decreased expression of RAD52 mRNA

NCBI chr 4:154,778,320...154,802,002
Ensembl chr 4:154,778,320...154,800,021

G

RAD54 like 2

decreases expression

EXP

furan results in decreased expression of RAD54L2 mRNA

NCBI chr 8:116,203,655...116,305,723
Ensembl chr 8:116,203,655...116,305,849

G

RALY heterogeneous nuclear ribonucleoprotein

increases methylation

EXP

furan results in increased methylation of RALY gene

NCBI chr 3:163,766,183...163,830,726
Ensembl chr 3:163,766,478...163,830,740

G

RNA guanine-7 methyltransferase activating subunit

increases expression
increases methylation

EXP

furan results in increased expression of RAMAC mRNA
furan results in increased methylation of RAMAC gene

PMID:22079235 PMID:25539665

NCBI chr 1:145,117,752...145,123,640
Ensembl chr 1:145,117,736...145,124,256

G

receptor activity modifying protein 3

increases expression

EXP

furan results in increased expression of RAMP3 mRNA

NCBI chr14:85,741,314...85,758,813
Ensembl chr14:85,755,211...85,758,818

G

RAN, member RAS oncogene family

increases expression

EXP

furan results in increased expression of RAN mRNA

PMID:22079235 PMID:26194646

NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317

G

RAN binding protein 17

decreases expression

EXP

furan results in decreased expression of RANBP17 mRNA

NCBI chr10:18,304,634...18,607,162
Ensembl chr10:18,305,227...18,607,047

G

RAN binding protein 3-like

increases expression

EXP

furan results in increased expression of RANBP3L mRNA

NCBI chr 2:59,785,070...59,840,338
Ensembl chr 2:59,785,450...59,840,334

G

RAN binding protein 6

decreases expression

EXP

furan results in decreased expression of RANBP6 mRNA

PMID:25539665 PMID:26194646

NCBI chr 1:236,985,930...236,990,451
Ensembl chr 1:236,985,602...236,990,576

G

RAN guanine nucleotide release factor

increases methylation
increases expression

EXP

furan results in increased methylation of RANGRF gene
furan results in increased expression of RANGRF mRNA

PMID:22079235 PMID:25539665

NCBI chr10:54,176,325...54,177,696
Ensembl chr10:54,176,325...54,177,696

G

Rap1 GTPase-activating protein

increases expression

EXP

furan results in increased expression of RAP1GAP mRNA

NCBI chr 5:155,157,511...155,222,622
Ensembl chr 5:155,157,558...155,222,622

G

Rap guanine nucleotide exchange factor 5

increases expression

EXP

furan results in increased expression of RAPGEF5 mRNA

NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908

G

receptor-associated protein of the synapse

increases methylation

EXP

furan results in increased methylation of RAPSN gene

NCBI chr 3:97,470,891...97,480,196
Ensembl chr 3:97,470,881...97,480,196

G

retinoic acid receptor, alpha

increases methylation

EXP

furan results in increased methylation of RARA gene

NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160

G

retinoic acid receptor responder 1

decreases expression

EXP

furan results in decreased expression of RARRES1 mRNA

NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024

G

RASD family, member 2

decreases expression

EXP

furan results in decreased expression of RASD2 mRNA

NCBI chr19:13,600,028...13,610,753
Ensembl chr19:13,599,986...13,610,753

G

RAS-like family 11 member A

increases methylation

EXP

furan results in increased methylation of RASL11A gene

NCBI chr12:13,372,023...13,374,784
Ensembl chr12:13,372,023...13,376,451

G

RAS-like family 11 member B

decreases methylation
increases expression

EXP

furan results in decreased methylation of RASL11B gene
furan results in increased expression of RASL11B mRNA

NCBI chr14:34,369,029...34,373,250
Ensembl chr14:34,368,726...34,373,250

G

RAS-like, family 12

increases expression

EXP

furan results in increased expression of RASL12 mRNA

NCBI chr 8:74,813,000...74,827,041
Ensembl chr 8:74,813,000...74,827,897

G

RAS-like, family 2, locus 9

increases expression

EXP

furan results in increased expression of RASL2-9 mRNA

NCBI chr 1:77,749,728...77,750,905
Ensembl chr 1:77,749,091...77,751,537

G

Ras association domain family member 1

decreases expression
increases expression
increases methylation

EXP
ISO

furan results in decreased expression of RASSF1 mRNA
furan results in increased expression of RASSF1 mRNA
furan results in increased methylation of RASSF1 promoter

PMID:24183702 PMID:24614236

NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805

G

Ras association domain family member 3

decreases expression

EXP

furan results in decreased expression of RASSF3 mRNA

NCBI chr 7:58,821,360...58,886,020
Ensembl chr 7:58,821,360...58,886,020

G

Ras association domain family member 9

increases expression

EXP

furan results in increased expression of RASSF9 mRNA

NCBI chr 7:39,486,257...39,518,090
Ensembl chr 7:39,409,870...39,519,675

G

RB transcriptional corepressor 1

decreases expression

EXP

furan results in decreased expression of RB1 mRNA

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

RB binding protein 7, chromatin remodeling factor

increases expression

EXP

furan results in increased expression of RBBP7 mRNA

NCBI chr X:35,544,873...35,563,030
Ensembl chr X:35,544,873...35,563,030

G

RB transcriptional corepressor like 1

increases expression

EXP

furan results in increased expression of RBL1 mRNA

NCBI chr 3:166,226,187...166,289,862
Ensembl chr 3:166,226,198...166,289,376

G

RNA binding motif protein 24

decreases methylation
increases expression

EXP

furan results in decreased methylation of RBM24 gene
furan results in increased expression of RBM24 mRNA

NCBI chr17:18,481,893...18,494,440
Ensembl chr17:18,481,900...18,494,604

G

RNA binding motif protein 27

increases methylation

EXP

furan results in increased methylation of RBM27 gene

NCBI chr18:34,524,523...34,587,115
Ensembl chr18:34,524,551...34,587,111

G

retinol binding protein 1

increases expression

ISO

furan results in increased expression of RBP1 mRNA

NCBI chr 8:107,904,589...107,926,109
Ensembl chr 8:107,887,417...107,983,847

G

retinol binding protein 7

increases expression

EXP

furan results in increased expression of RBP7 mRNA

PMID:25539665 PMID:26194646

NCBI chr 5:165,169,700...165,177,427
Ensembl chr 5:165,172,785...165,177,399

G

recombination signal binding protein for immunoglobulin kappa J region-like

increases expression

EXP

furan results in increased expression of RBPJL mRNA

PMID:25539665 PMID:38160780

NCBI chr 3:173,553,389...173,565,869
Ensembl chr 3:173,553,498...173,565,869

G

recombination signal binding protein for immunoglobulin kappa J region-like 2

increases expression

EXP

furan results in increased expression of RBPJL2 mRNA

NCBI chr 5:10,248,069...10,249,467

G

regulator of calcineurin 1

increases methylation
decreases expression
increases expression

EXP
ISO

furan results in increased methylation of RCAN1 gene
furan results in decreased expression of RCAN1 mRNA
furan results in increased expression of RCAN1 mRNA

PMID:22079235 PMID:24183702 PMID:26194646

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236

G

RCC1 and BTB domain containing protein 1

decreases expression

EXP

furan results in decreased expression of RCBTB1 mRNA

NCBI chr15:37,430,453...37,477,920
Ensembl chr15:37,435,070...37,480,803

G

reticulocalbin 2

increases expression

EXP

furan results in increased expression of RCN2 mRNA

PMID:25539665 PMID:27387713

NCBI chr 8:65,345,247...65,362,290
Ensembl chr 8:65,345,273...65,364,632

G

reticulocalbin 3

increases expression

EXP

furan results in increased expression of RCN3 mRNA

NCBI chr 1:104,700,969...104,710,228
Ensembl chr 1:104,700,545...104,710,249

G

RD3 regulator of GUCY2D

decreases expression

EXP

furan results in decreased expression of RD3 mRNA

NCBI chr13:106,060,657...106,097,063
Ensembl chr13:106,084,171...106,093,540

G

retinol dehydrogenase 7

decreases expression

EXP

furan results in decreased expression of RDH7 mRNA

NCBI chr 7:65,561,259...65,574,618
Ensembl chr 7:65,560,822...65,574,635

G

REC8 meiotic recombination protein

increases expression

EXP

furan results in increased expression of REC8 mRNA

NCBI chr15:33,079,818...33,087,283
Ensembl chr15:33,079,801...33,087,282

G

RecQ like helicase 4

increases methylation

EXP

furan results in increased methylation of RECQL4 gene

NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258

G

RecQ like helicase 5

increases methylation

EXP

furan results in increased methylation of RECQL5 gene

NCBI chr10:101,625,477...101,664,582
Ensembl chr10:101,625,480...101,664,663

G

receptor accessory protein 1

decreases expression

EXP

furan results in decreased expression of REEP1 mRNA

NCBI chr 4:105,303,974...105,420,611
Ensembl chr 4:105,303,969...105,420,602

G

receptor accessory protein 3

increases methylation

EXP

furan results in increased methylation of REEP3 gene

NCBI chr20:21,492,695...21,575,138
Ensembl chr20:21,492,721...21,577,521

G

receptor accessory protein 6

increases methylation
increases expression

EXP

furan results in increased methylation of REEP6 gene
furan results in increased expression of REEP6 mRNA

PMID:22079235 PMID:25539665 PMID:26194646

NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740

G

regenerating family member 1 alpha

increases expression

EXP

furan results in increased expression of REG1A mRNA

NCBI chr 4:112,450,466...112,453,130
Ensembl chr 4:112,450,468...112,453,585

G

regenerating family member 3 beta

increases expression

EXP

furan results in increased expression of REG3A mRNA; furan results in increased expression of REG3B mRNA

NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014

G

regenerating family member 3 gamma

increases expression

EXP

furan results in increased expression of REG3G mRNA

NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738

G

regenerating family member 4

increases expression

EXP

furan results in increased expression of REG4 mRNA

NCBI chr 2:188,507,684...188,521,990
Ensembl chr 2:188,507,684...188,521,990

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases phosphorylation

ISO

rhodioloside inhibits the reaction [furan results in increased phosphorylation of RELA protein]

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

RELT-like 1

increases expression

EXP

furan results in increased expression of RELL1 mRNA

NCBI chr14:44,672,121...44,732,081
Ensembl chr14:44,672,224...44,732,088

G

RELT-like 2

increases expression

EXP

furan results in increased expression of RELL2 mRNA

NCBI chr18:30,041,204...30,045,193
Ensembl chr18:30,041,563...30,045,187

G

RAB15 effector protein

increases expression

EXP

furan results in increased expression of REP15 mRNA

NCBI chr 4:181,682,588...181,683,661
Ensembl chr 4:181,682,588...181,683,661

G

retention in endoplasmic reticulum sorting receptor 1

increases methylation

EXP

furan results in increased methylation of RER1 gene

NCBI chr 5:170,916,643...170,929,073
Ensembl chr 5:170,916,905...170,928,980

G

reticulophagy regulator 1

increases expression

EXP

furan results in increased expression of RETREG1 mRNA

NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356

G

REV3 like, DNA directed polymerase zeta catalytic subunit

increases expression

EXP

furan results in increased expression of REV3L mRNA

NCBI chr20:44,686,482...44,844,668
Ensembl chr20:44,686,940...44,844,668

G

required for excision 1-B domain containing

increases methylation

EXP

furan results in increased methylation of REX1BD gene

NCBI chr16:18,956,023...18,958,494
Ensembl chr16:18,955,969...18,958,494

G

RNA exonuclease 5

increases expression

EXP

furan results in increased expression of REXO5 mRNA

NCBI chr 1:183,599,954...183,698,433
Ensembl chr 1:183,600,037...183,672,850

G

replication factor C subunit 3

increases expression

EXP

furan results in increased expression of RFC3 mRNA

NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340

G

replication factor C subunit 4

increases expression

EXP

furan results in increased expression of RFC4 mRNA

NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730

G

refilin A

decreases expression

EXP

furan results in decreased expression of RFLNA mRNA

NCBI chr12:37,294,643...37,323,373
Ensembl chr12:37,294,643...37,303,535

G

refilin B

increases expression

EXP

furan results in increased expression of RFLNB mRNA

NCBI chr10:61,391,947...61,398,224
Ensembl chr10:61,390,659...61,398,224

G

regulatory factor X4

decreases expression

ISO

furan results in decreased expression of RFX4 mRNA

NCBI chr 7:20,740,760...20,903,355
Ensembl chr 7:20,741,079...20,902,851

G

regulatory factor X5

decreases expression

EXP

furan results in decreased expression of RFX5 mRNA

NCBI chr 2:185,210,206...185,217,735
Ensembl chr 2:185,210,217...185,217,743

G

regulatory factor X, 6

increases expression

EXP

furan results in increased expression of RFX6 mRNA

NCBI chr20:31,562,490...31,615,967
Ensembl chr20:31,562,490...31,615,967

G

regulatory factor X-associated ankyrin-containing protein

decreases expression

ISO

furan results in decreased expression of RFXANK mRNA

NCBI chr16:19,314,307...19,322,827
Ensembl chr16:19,314,759...19,325,248

G

regucalcin

affects binding
decreases expression

EXP

furan binds to RGN protein
furan results in decreased expression of RGN mRNA

PMID:22240984 PMID:26194646

NCBI chr X:4,172,537...4,190,112
Ensembl chr X:4,172,537...4,190,251

G

retinal G protein coupled receptor

decreases methylation
increases expression

EXP

furan results in decreased methylation of RGR gene
furan results in increased expression of RGR mRNA

PMID:22079235 PMID:25539665

NCBI chr16:12,821,858...12,836,665
Ensembl chr16:12,821,858...12,836,486

G

regulator of G-protein signaling 10

increases expression

EXP

furan results in increased expression of RGS10 mRNA

NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904

G

regulator of G-protein signaling 16

decreases expression

ISO

furan results in decreased expression of RGS16 mRNA

NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313

G

regulator of G-protein signaling 2

decreases methylation

EXP

furan results in decreased methylation of RGS2 gene

NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697

G

regulator of G-protein signaling 3

decreases expression

EXP

furan results in decreased expression of RGS3 mRNA

NCBI chr 5:81,037,588...81,177,446
Ensembl chr 5:81,056,068...81,177,445

G

regulator of G-protein signaling 5

increases expression

EXP

furan results in increased expression of RGS5 mRNA

PMID:25539665 PMID:26194646

NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352

G

regulator of G-protein signaling 7 binding protein

increases expression

EXP

furan results in increased expression of RGS7BP mRNA

NCBI chr 2:37,867,698...37,965,587
Ensembl chr 2:37,872,949...37,965,253

G

regulator of G protein signaling 9 binding protein

decreases expression

EXP

furan results in decreased expression of RGS9BP mRNA

NCBI chr 1:97,386,326...97,387,039
Ensembl chr 1:97,386,326...97,387,039

G

regulator of G-protein signaling like 2 homolog (mouse)

decreases expression

EXP

furan results in decreased expression of RGSL2H mRNA

NCBI chr13:68,524,140...68,525,147
Ensembl chr13:68,524,140...68,525,147

G

Rh-associated glycoprotein

decreases expression

EXP

furan results in decreased expression of RHAG mRNA

NCBI chr 9:27,566,349...27,594,390
Ensembl chr 9:27,566,356...27,594,390

G

rhomboid domain containing 2

increases expression

EXP

furan results in increased expression of RHBDD2 mRNA

PMID:25539665 PMID:26194646

NCBI chr12:26,680,206...26,690,926
Ensembl chr12:26,680,969...26,691,080

G

rhomboid like 2

increases expression

EXP

furan results in increased expression of RHBDL2 mRNA

NCBI chr 5:141,322,246...141,376,702
Ensembl chr 5:141,322,354...141,366,747

G

Rh family B glycoprotein

increases expression

EXP

furan results in increased expression of RHBG mRNA

NCBI chr 2:176,002,886...176,015,201
Ensembl chr 2:176,002,887...176,015,609

G

RHEB like 1

increases methylation
increases expression

EXP

furan results in increased methylation of RHEBL1 gene
furan results in increased expression of RHEBL1 mRNA

PMID:22079235 PMID:25539665

NCBI chr 7:131,905,207...131,910,088
Ensembl chr 7:131,905,207...131,909,199

G

Rho-related BTB domain containing 1

increases methylation

EXP

furan results in increased methylation of RHOBTB1 gene

NCBI chr20:19,326,197...19,455,182
Ensembl chr20:19,326,212...19,402,057

G

Rho-related BTB domain containing 2

increases expression

EXP

furan results in increased expression of RHOBTB2 mRNA

NCBI chr15:51,278,024...51,298,209
Ensembl chr15:51,280,149...51,298,209

G

ras homolog family member C

increases expression
decreases methylation

EXP

furan results in increased expression of RHOC mRNA
furan results in decreased methylation of RHOC gene

PMID:26194646 PMID:27387713

NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745

G

ras homolog family member J

increases expression

EXP

furan results in increased expression of RHOJ mRNA

NCBI chr 6:99,771,104...99,853,366
Ensembl chr 6:99,771,252...99,853,999

G

ras homolog family member T2

increases methylation

EXP

furan results in increased methylation of RHOT2 gene

NCBI chr10:15,363,467...15,369,263
Ensembl chr10:15,361,726...15,369,006

G

RIC8 guanine nucleotide exchange factor A

increases methylation

EXP

furan results in increased methylation of RIC8A gene

NCBI chr 1:205,364,796...205,371,102
Ensembl chr 1:205,363,882...205,371,102

G

reactive intermediate imine deaminase A homolog

affects binding
increases methylation

EXP

furan binds to RIDA protein
furan results in increased methylation of RIDA gene

PMID:22079235 PMID:22240984

NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692

G

Rab interacting lysosomal protein

decreases expression

EXP

furan results in decreased expression of RILP mRNA

NCBI chr10:60,853,316...60,857,096
Ensembl chr10:60,853,547...60,857,092

G

receptor-interacting serine-threonine kinase 2

increases expression

EXP

furan results in increased expression of RIPK2 mRNA

NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663

G

RHO family interacting cell polarization regulator 2

increases expression

EXP

furan results in increased expression of RIPOR2 mRNA

NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,751,771...40,975,337

G

ring finger protein, LIM domain interacting

increases methylation

EXP

furan results in increased methylation of RLIM gene

NCBI chr X:73,048,983...73,070,302
Ensembl chr X:73,054,098...73,069,992

G

relaxin 3

decreases expression

EXP

furan results in decreased expression of RLN3 mRNA

NCBI chr19:41,012,168...41,014,199
Ensembl chr19:41,012,168...41,014,653

G

regulator of microtubule dynamics 2

decreases expression

EXP

furan results in decreased expression of RMDN2 mRNA

NCBI chr 6:21,101,383...21,195,221
Ensembl chr 6:21,119,396...21,193,684

G

ribonuclease A family member 10

increases methylation

EXP

furan results in increased methylation of RNASE10 gene

NCBI chr15:26,700,219...26,702,681
Ensembl chr15:26,688,102...26,706,105

G

ribonuclease, RNase A family, 1-like 2

increases methylation

EXP

furan results in increased methylation of RNASE1L2 gene

NCBI chr15:26,895,318...26,897,025
Ensembl chr15:26,895,411...26,897,024

G

ribonuclease A family member 4

decreases expression

EXP

furan results in decreased expression of RNASE4 mRNA

NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639

G

Rho family GTPase 1

decreases expression

ISO

furan results in decreased expression of RND1 mRNA

NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:131,700,321...131,707,392

G

Rho family GTPase 2

increases expression

ISO

furan results in increased expression of RND2 mRNA

NCBI chr10:86,899,395...86,902,992
Ensembl chr10:86,899,395...86,902,992

G

ring finger protein 125

increases methylation
decreases expression

EXP

furan results in increased methylation of RNF125 gene
furan results in decreased expression of RNF125 mRNA

PMID:22079235 PMID:26194646

NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,528,838...12,554,430

G

ring finger protein 144B

decreases expression

EXP

furan results in decreased expression of RNF144B mRNA

PMID:25539665 PMID:26194646

NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,639,079...17,769,037

G

ring finger protein 186

increases expression

EXP

furan results in increased expression of RNF186 mRNA

NCBI chr 5:156,493,750...156,494,974
Ensembl chr 5:156,493,752...156,494,978

G

ring finger protein 19A, RBR E3 ubiquitin protein ligase

increases methylation

EXP

furan results in increased methylation of RNF19A gene

NCBI chr 7:69,310,947...69,350,567
Ensembl chr 7:69,310,947...69,350,225

G

ring finger protein 225

increases methylation

EXP

furan results in increased methylation of RNF225 gene

NCBI chr 1:82,615,787...82,618,456
Ensembl chr 1:82,615,787...82,618,456

G

ring finger protein 34

increases methylation

EXP

furan results in increased methylation of RNF34 gene

NCBI chr12:39,364,461...39,385,391
Ensembl chr12:39,355,578...39,385,340

G

ring finger protein 38

increases methylation

EXP

furan results in increased methylation of RNF38 gene

NCBI chr 5:63,154,507...63,263,138
Ensembl chr 5:63,154,507...63,263,137

G

ring finger protein 39

decreases expression

EXP

furan results in decreased expression of RNF39 mRNA

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323

G

ring finger protein 8

increases methylation

EXP

furan results in increased methylation of RNF8 gene

NCBI chr20:7,683,890...7,708,437

G

rhophilin associated tail protein 1

increases expression

EXP

furan results in increased expression of ROPN1 mRNA

PMID:25539665 PMID:26194646

NCBI chr11:79,603,053...79,632,344
Ensembl chr11:79,603,055...79,632,344

G

receptor tyrosine kinase-like orphan receptor 2

increases expression

EXP

furan results in increased expression of ROR2 mRNA

NCBI chr17:12,124,749...12,300,044
Ensembl chr17:12,124,749...12,300,044

G

replication protein A1

increases methylation

EXP

furan results in increased methylation of RPA1 gene

NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279

G

ribulose-5-phosphate-3-epimerase

increases expression

EXP

furan results in increased expression of RPE mRNA

NCBI chr 9:75,640,867...75,661,009
Ensembl chr 9:75,640,982...75,661,643

G

ribosome production factor 2 homolog

increases methylation

EXP

furan results in increased methylation of RPF2 gene

NCBI chr20:45,184,511...45,205,983
Ensembl chr20:45,184,512...45,206,001

G

ribosomal protein L12

increases expression

EXP

furan results in increased expression of RPL12 mRNA

NCBI chr 3:36,661,940...36,664,314
Ensembl chr 3:36,661,939...36,664,306

G

ribosomal protein L12, pseudogene 1

increases expression

EXP

furan results in increased expression of RPL12-PS1 mRNA

NCBI chr 8:87,939,763...87,940,495
Ensembl chr 7:54,252,544...54,253,455

G

ribosomal protein L13

increases expression

EXP

furan results in increased expression of RPL13 mRNA

NCBI chr19:68,062,442...68,065,065
Ensembl chr19:68,062,493...68,065,059

G

ribosomal protein L14

increases expression

EXP

furan results in increased expression of RPL14 mRNA

NCBI chr 8:129,163,620...129,166,745
Ensembl chr 8:129,163,317...129,167,459

G

ribosomal protein L15 like 1

increases expression

EXP

furan results in increased expression of RPL15L1 mRNA

NCBI chr12:15,340,865...15,341,630
Ensembl chr12:15,340,851...15,341,680

G

ribosomal protein L18A like 1

increases expression

EXP

furan results in increased expression of RPL18AL1 mRNA

NCBI chr 1:70,167,106...70,167,704
Ensembl chr 1:70,166,729...70,167,654

G

ribosomal protein L23A

increases expression

EXP

furan results in increased expression of RPL23A mRNA

NCBI chr10:63,574,732...63,577,511
Ensembl chr10:63,574,732...63,581,606

G

ribosomal protein L27a, pseudogene 14

increases expression

EXP

furan results in increased expression of RPL27A-PS14 mRNA

NCBI chr 6:41,230,228...41,230,708

G

ribosomal protein L27 like 2

increases methylation

EXP

furan results in increased methylation of RPL27L2 gene

NCBI chr 1:162,565,660...162,566,064
Ensembl chr 1:162,565,660...162,566,064

G

ribosomal protein L28

increases expression

EXP

furan results in increased expression of RPL28 mRNA

NCBI chr 1:78,080,945...78,083,532
Ensembl chr 1:78,080,945...78,083,771

G

ribosomal protein L31

increases methylation

EXP

furan results in increased methylation of RPL31 gene

NCBI chr 9:49,143,044...49,147,155
Ensembl chr 9:49,142,955...49,147,155

G

ribosomal protein L7

increases methylation

EXP

furan results in increased methylation of RPL7 gene

NCBI chr 5:8,000,446...8,003,454
Ensembl chr 5:7,850,630...8,003,451

G

ribosomal protein L8

increases expression

EXP

furan results in increased expression of RPL8 mRNA

NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103
Ensembl chr 3:110,506,800...110,509,103

G

ribosomal protein lateral stalk subunit P2

increases methylation

EXP

furan results in increased methylation of RPLP2 gene

NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191

G

ribonuclease P and MRP subunit p25

increases methylation

EXP

furan results in increased methylation of RPP25 gene

NCBI chr 8:66,803,262...66,804,642
Ensembl chr 8:66,803,212...66,810,550

G

reprimo, TP53 dependent G2 arrest mediator homolog

decreases expression

EXP

furan results in decreased expression of RPRM mRNA

NCBI chr 3:58,948,618...58,950,035
Ensembl chr 3:58,799,866...58,950,542

G

reprimo-like

increases expression

EXP

furan results in increased expression of RPRML mRNA

NCBI chr10:89,060,280...89,061,284
Ensembl chr10:89,059,522...89,063,831

G

ribosomal protein S12-like 4

increases methylation

EXP

furan results in increased methylation of RPS12L4 gene

NCBI chr 7:25,006,242...25,007,029
Ensembl chr 7:25,005,384...25,008,327

G

ribosomal protein S15a

increases expression

EXP

furan results in increased expression of RPS15A mRNA

NCBI chr 1:181,854,396...181,861,330
Ensembl chr 1:181,854,396...181,861,201

G

ribosomal protein S19

increases expression

EXP

furan results in increased expression of RPS19 mRNA

NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132

G

ribosomal protein S19, pseudogene 18

increases expression

EXP

furan results in increased expression of RPS19-PS18 mRNA

NCBI chr 6:77,806,708...77,807,217

G

ribosomal protein S2

increases expression

EXP

furan results in increased expression of RPS2 mRNA

NCBI chr10:14,251,841...14,253,697
Ensembl chr10:14,251,380...14,253,695

G

ribosomal protein S21, pseudogene 1

increases methylation

EXP

furan results in increased methylation of RPS21 gene

NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490

G

ribosomal protein S27a

increases methylation

EXP

furan results in increased methylation of RPS27A gene

NCBI chr14:107,486,664...107,488,941
Ensembl chr 5:138,465,088...138,466,080
Ensembl chr14:138,465,088...138,466,080
Ensembl chr 5:138,465,088...138,466,080

G

ribosomal protein S4, X-linked, pseudogene 13

increases expression

EXP

furan results in increased expression of RPS4Y2 mRNA

NCBI chr 4:183,000,913...183,001,846
Ensembl chr 4:183,000,652...183,007,381

G

ribosomal protein S6 kinase C1

increases methylation

EXP

furan results in increased methylation of RPS6KC1 gene

NCBI chr13:104,877,296...105,021,490
Ensembl chr13:104,877,296...105,021,435

G

ribosomal protein S6 kinase-like 1

increases methylation

EXP

furan results in increased methylation of RPS6KL1 gene

NCBI chr 6:110,514,322...110,530,955
Ensembl chr 6:110,514,017...110,530,929

G

ribosomal protein S8

increases expression

ISO

furan results in increased expression of RPS8 mRNA

NCBI chr 5:135,866,941...135,869,511
Ensembl chr 5:135,866,941...135,869,548

G

ribosomal protein SA

increases expression

EXP

furan results in increased expression of RPSA mRNA

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737

G

RRAD, Ras related glycolysis inhibitor and calcium channel regulator

increases expression

EXP

furan results in increased expression of RRAD mRNA

NCBI chr19:360,581...363,874
Ensembl chr19:360,973...363,871

G

ribonucleotide reductase catalytic subunit M1

increases expression

EXP

furan results in increased expression of RRM1 mRNA

NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944

G

ribonucleotide reductase regulatory subunit M2

increases expression

EXP

furan results in increased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370

G

ribosome biogenesis regulator 1 homolog

increases expression

EXP

furan results in increased expression of RRS1 mRNA

NCBI chr 5:14,516,303...14,517,936
Ensembl chr 5:14,515,254...14,517,943

G

regulator of sex limited protein 1

increases expression

EXP

furan results in increased expression of RSL1 mRNA

NCBI chr 2:86,447,861...86,472,387
Ensembl chr 2:86,448,581...86,472,380

G

ribosomal L1 domain containing 1

increases expression

EXP

furan results in increased expression of RSL1D1 mRNA

NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566

G

R-spondin 1

increases expression

EXP

furan results in increased expression of RSPO1 mRNA

NCBI chr 5:142,536,162...142,557,611
Ensembl chr 5:142,536,344...142,557,776

G

arginine and serine rich coiled-coil 1

increases methylation

EXP

furan results in increased methylation of RSRC1 gene

NCBI chr 2:153,536,839...153,942,825
Ensembl chr 2:153,541,161...153,942,824

G

arginine and serine rich protein 1

decreases expression

EXP

furan results in decreased expression of RSRP1 mRNA

NCBI chr 5:152,431,448...152,435,202
Ensembl chr 5:152,431,478...152,435,126

G

RT1 class II, locus Bb

increases expression

EXP

furan results in increased expression of RT1-BB mRNA

NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118

G

RT1 class II, locus DOb

increases expression

EXP

furan results in increased expression of RT1-DOB mRNA

NCBI chr20:4,621,336...4,627,537
Ensembl chr20:4,619,694...4,627,523

G

RT1 class Ib, locus M3, gene 1

increases expression

EXP

furan results in increased expression of RT1-M3-1 mRNA

NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366

G

RT1 class Ib, locus M5

increases expression

EXP

furan results in increased expression of RT1-M5 mRNA

NCBI chr20:1,551,751...1,554,015
Ensembl chr20:1,549,836...1,558,362

G

RT1 class I, locus M6, gene 1

increases expression

EXP

furan results in increased expression of RT1-M6-1 mRNA

NCBI chr20:1,571,471...1,574,387
Ensembl chr20:1,571,442...1,575,632

G

RT1 class I, locus T24, gene 4

increases methylation

EXP

furan results in increased methylation of RT1-T24-4 gene

NCBI chr20:2,689,329...2,749,848
Ensembl chr20:2,689,315...2,747,100

G

rhotekin

increases expression

EXP

furan results in increased expression of RTKN mRNA

NCBI chr 4:117,198,496...117,215,660
Ensembl chr 4:117,198,647...117,215,660

G

reticulon 4

increases expression

EXP

furan results in increased expression of RTN4 mRNA

NCBI chr14:107,651,001...107,698,610
Ensembl chr14:107,650,732...107,698,611

G

reticulon 4 receptor-like 1

decreases expression

EXP

furan results in decreased expression of RTN4RL1 mRNA

NCBI chr10:60,541,584...60,615,302
Ensembl chr10:60,520,760...60,615,727

G

receptor (chemosensory) transporter protein 3

decreases expression

EXP

furan results in decreased expression of RTP3 mRNA

NCBI chr 8:119,847,947...119,853,549
Ensembl chr 8:119,848,556...119,853,095

G

RUNX1 partner transcriptional co-repressor 1

increases expression

EXP

furan results in increased expression of RUNX1T1 mRNA

NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:31,984,855...32,132,855

G

urinary protein 2

decreases expression

EXP

furan results in decreased expression of RUP2 mRNA

PMID:15120968 PMID:26194646

NCBI chr 8:43,547,875...43,551,456
Ensembl chr 8:43,549,809...43,700,211

G

RWD domain containing 3

increases methylation

EXP

furan results in increased methylation of RWDD3 gene

NCBI chr 2:211,918,361...211,933,644
Ensembl chr 2:211,918,361...211,933,592

G

S100 calcium binding protein A1

increases expression

EXP

furan results in increased expression of S100A1 mRNA

NCBI chr 2:178,291,503...178,296,346
Ensembl chr 2:178,291,503...178,296,346

G

S100 calcium binding protein A10

increases expression
decreases methylation

EXP

furan results in increased expression of S100A10 mRNA
furan results in decreased methylation of S100A10 gene

PMID:20124500 PMID:26194646 PMID:27387713

NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103

G

S100 calcium binding protein A11

increases expression

EXP

furan results in increased expression of S100A11 mRNA

NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541

G

S100 calcium-binding protein A4

increases expression

EXP

furan results in increased expression of S100A4 mRNA

NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837

G

S100 calcium binding protein A6

increases expression

EXP

furan results in increased expression of S100A6 mRNA

NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762

G

sphingosine-1-phosphate receptor 1

decreases expression

EXP

furan results in decreased expression of S1PR1 mRNA

NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689

G

sphingosine-1-phosphate receptor 2

increases methylation

EXP

furan results in increased methylation of S1PR2 gene

NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:27,774,566...27,790,577

G

serum amyloid A4

increases methylation

EXP

furan results in increased methylation of SAA4 gene

NCBI chr 1:106,383,856...106,388,158
Ensembl chr 1:106,383,856...106,387,354

G

S-antigen visual arrestin

increases expression

EXP

furan results in increased expression of SAG mRNA

NCBI chr 9:95,915,640...95,956,641
Ensembl chr 9:95,917,197...95,956,507

G

spalt-like transcription factor 1

increases expression

EXP

furan results in increased expression of SALL1 mRNA

NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278

G

spalt-like transcription factor 2

increases expression

EXP

furan results in increased expression of SALL2 mRNA

NCBI chr15:27,494,831...27,512,402
Ensembl chr15:27,494,589...27,512,402

G

spalt-like transcription factor 3

increases methylation

EXP

furan results in increased methylation of SALL3 gene

NCBI chr18:76,680,997...76,700,905
Ensembl chr18:76,681,005...76,700,905

G

sterile alpha motif domain containing 4A

increases methylation
increases expression

EXP
ISO

furan results in increased methylation of SAMD4A gene
furan results in increased expression of SAMD4A mRNA
furan results in increased expression of SAMD4 mRNA

PMID:22079235 PMID:24183702 PMID:25539665

NCBI chr15:22,616,200...22,831,872
Ensembl chr15:22,614,287...22,831,872

G

sterile alpha motif domain containing 9 like

increases expression

EXP

furan results in increased expression of SAMD9L mRNA

NCBI chr 4:32,316,748...32,331,112
Ensembl chr 4:32,222,623...32,331,067

G

sarcosine dehydrogenase

increases methylation
increases expression

EXP

furan results in increased methylation of SARDH gene
furan results in increased expression of SARDH mRNA

PMID:22079235 PMID:26194646

NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137

G

sterile alpha and TIR motif containing 1

increases methylation

EXP

furan results in increased methylation of SARM1 gene

NCBI chr10:63,867,503...63,890,872
Ensembl chr10:63,867,503...63,890,872

G

stabilizer of axonemal microtubules 2

increases expression

EXP

furan results in increased expression of SAXO2 mRNA

NCBI chr 1:146,004,694...146,047,662
Ensembl chr 1:146,032,694...146,047,636

G

stabilizer of axonemal microtubules 5

increases methylation

EXP

furan results in increased methylation of SAXO5 gene

NCBI chr12:6,318,845...6,336,018
Ensembl chr12:6,318,903...6,336,009

G

strawberry notch homolog 1

increases methylation

EXP

furan results in increased methylation of SBNO1 gene

NCBI chr12:37,835,306...37,895,861
Ensembl chr12:37,846,514...37,891,231

G

spermine binding protein

increases expression

EXP

furan results in increased expression of SBP mRNA

NCBI chr10:13,450,613...13,473,016
Ensembl chr10:13,469,303...13,473,016

G

suppressor of cancer cell invasion

decreases expression

ISO

furan results in decreased expression of SCAI mRNA

NCBI chr 3:43,222,983...43,335,056
Ensembl chr 3:43,222,983...43,335,025

G

secretory carrier membrane protein 5

increases expression

EXP

furan results in increased expression of SCAMP5 mRNA

NCBI chr 8:66,739,794...66,778,538
Ensembl chr 8:66,741,940...66,751,099

G

scavenger receptor class A, member 3

increases expression

EXP

furan results in increased expression of SCARA3 mRNA

NCBI chr15:44,315,422...44,348,416
Ensembl chr15:44,315,422...44,348,551

G

scavenger receptor class A, member 5

decreases expression
increases expression

EXP

furan results in decreased expression of SCARA5 mRNA
furan results in increased expression of SCARA5 mRNA

PMID:25539665 PMID:27387713

NCBI chr15:44,055,576...44,160,593
Ensembl chr15:44,055,630...44,160,585

G

scavenger receptor class F, member 2

increases expression
decreases methylation

EXP

furan results in increased expression of SCARF2 mRNA
furan results in decreased methylation of SCARF2 gene

NCBI chr11:96,680,237...96,691,686
Ensembl chr11:96,680,243...96,691,626

G

scavenger receptor family member expressed on T-cells 1

decreases expression

EXP

furan results in decreased expression of CD163L1 mRNA

NCBI chr 1:204,450,386...204,462,094
Ensembl chr 1:204,450,386...204,461,441

G

stearoyl-CoA desaturase

increases methylation

EXP

furan results in increased methylation of SCD1 gene

NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785

G

secretogranin V

increases expression

EXP

furan results in increased expression of SCG5 mRNA

PMID:26194646 PMID:27387713

NCBI chr 3:120,998,420...121,042,881
Ensembl chr 3:120,998,420...121,042,795

G

secretoglobin family 1A member 1

decreases expression

EXP

furan results in decreased expression of SCGB1A1 mRNA

NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686

G

secretoglobin, family 1C, member 1

multiple interactions
increases expression

ISO
EXP

[Bromodeoxyuridine co-treated with furan] affects the expression of SCGB1C1 mRNA
furan results in increased expression of SCGB1C1 mRNA

PMID:24910943 PMID:25539665 PMID:26194646

NCBI chr 1:205,352,216...205,354,656
Ensembl chr 1:205,353,437...205,354,656

G

schwannomin interacting protein 1

increases expression

EXP

furan results in increased expression of SCHIP1 mRNA

NCBI chr 2:154,437,217...155,198,560
Ensembl chr 2:155,060,798...155,198,557

G

sodium voltage-gated channel beta subunit 1

decreases expression

EXP

furan results in decreased expression of SCN1B mRNA

NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:95,481,298...95,491,197

G

sodium voltage-gated channel alpha subunit 3

decreases methylation

EXP

furan results in decreased methylation of SCN3A gene

NCBI chr 3:70,554,496...70,666,198
Ensembl chr 3:70,556,224...70,666,198

G

sodium voltage-gated channel beta subunit 3

increases expression

EXP

furan results in increased expression of SCN3B mRNA

NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:49,527,577...49,550,018

G

sodium voltage-gated channel alpha subunit 5

increases expression

EXP

furan results in increased expression of SCN5A mRNA

NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470

G

sodium channel epithelial 1 subunit alpha

decreases expression

ISO

furan results in decreased expression of SCNN1A mRNA

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405

G

sodium channel epithelial 1 subunit beta

increases expression

EXP

furan results in increased expression of SCNN1B mRNA

NCBI chr 1:185,861,326...185,915,717
Ensembl chr 1:185,854,733...185,916,049

G

sterol carrier protein 2

decreases expression

EXP

furan results in decreased expression of SCP2 mRNA

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043

G

stimulator of chondrogenesis 1

increases methylation

EXP

furan results in increased methylation of SCRG1 gene

NCBI chr16:37,770,739...37,799,010
Ensembl chr16:37,770,739...37,799,010

G

secernin 1

increases methylation

EXP

furan results in increased methylation of SCRN1 gene

NCBI chr 4:84,962,450...85,024,577
Ensembl chr 4:84,965,751...85,031,205

G

secretin receptor

increases expression

EXP

furan results in increased expression of SCTR mRNA

NCBI chr13:33,680,562...33,744,049
Ensembl chr13:33,680,627...33,733,709

G

signal peptide, CUB domain and EGF like domain containing 3

decreases expression

EXP

furan results in decreased expression of SCUBE3 mRNA

NCBI chr20:6,200,891...6,232,848
Ensembl chr20:6,200,178...6,233,051

G

scleraxis bHLH transcription factor

increases expression

EXP

furan results in increased expression of SCX mRNA

NCBI chr 7:110,056,897...110,059,283
Ensembl chr 7:110,054,601...110,061,438

G

SDA1 domain containing 1

increases expression

EXP

furan results in increased expression of SDAD1 mRNA

NCBI chr14:16,025,726...16,052,565
Ensembl chr14:16,025,727...16,055,359

G

syndecan 2

decreases expression

EXP

furan results in decreased expression of SDC2 mRNA

NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294

G

syndecan 3

increases methylation

EXP

furan results in increased methylation of SDC3 gene

NCBI chr 5:148,249,792...148,282,524
Ensembl chr 5:148,271,842...148,280,614

G

syndecan 4

increases expression

EXP

furan results in increased expression of SDC4 mRNA

NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670

G

syndecan binding protein 2

increases expression

EXP

furan results in increased expression of SDCBP2 mRNA

PMID:26194646 PMID:27387713

NCBI chr 3:160,521,309...160,558,452
Ensembl chr 3:160,530,927...160,558,446

G

stromal cell-derived factor 2-like 1

decreases expression

EXP

furan results in decreased expression of SDF2L1 mRNA

NCBI chr11:97,376,878...97,379,120
Ensembl chr11:97,376,878...97,379,120

G

short chain dehydrogenase/reductase family 9C, member 7

decreases expression

ISO

furan results in decreased expression of SDR9C7 mRNA

NCBI chr 7:65,588,726...65,607,534
Ensembl chr 7:65,593,000...65,605,630

G

SEBOX homeobox

increases expression
decreases expression
increases methylation

ISO
EXP

furan results in increased expression of SEBOX mRNA
furan results in decreased expression of SEBOX mRNA
furan results in increased methylation of SEBOX gene

PMID:22079235 PMID:24183702 PMID:25539665 PMID:26194646

NCBI chr10:63,897,265...63,898,136
Ensembl chr10:63,897,217...63,898,719

G

SEC13 homolog, nuclear pore and COPII coat complex component

affects binding

EXP

furan binds to SEC13 protein

NCBI chr 4:148,433,344...148,446,735
Ensembl chr 4:148,433,349...148,446,755

G

SEC61 translocon subunit beta

increases methylation

EXP

furan results in increased methylation of SEC61B gene

NCBI chr 5:66,569,184...66,577,394
Ensembl chr 5:66,569,196...66,580,028

G

SEL1L adaptor subunit of SYVN1 ubiquitin ligase

decreases expression

EXP

furan results in decreased expression of SEL1L mRNA

PMID:25539665 PMID:26194646

NCBI chr 6:116,466,163...116,510,436
Ensembl chr 6:116,466,163...116,510,578

G

selectin E

increases expression

EXP

furan results in increased expression of SELE mRNA

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903

G

selenoprotein M

increases expression

EXP

furan results in increased expression of SELENOM mRNA

NCBI chr14:82,619,453...82,622,056
Ensembl chr14:82,619,436...82,622,054

G

selenoprotein P

increases methylation

EXP

furan results in increased methylation of SELENOP gene

NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019

G

semaphorin 3B

increases expression

EXP

furan results in increased expres