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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfonamide
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Accession:CHEBI:35358 term browser browse the term
Definition:An amide of a sulfonic acid RS(=O)2NR'2.
Synonyms:related_synonym: sulfonamides
 xref: pubmed:11498380;   pubmed:2434548;   pubmed:26811268;   pubmed:26832216;   wikipedia.en:Sulfonamide
 chemrof_formula: NO2SR3
 chemrof_smiles: [1*]S(=O)(=O)N([2*])[3*]


show annotations for term's descendants           Sort by:
1-(5-isoquinolinesulfonyl)-2-methylpiperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein] CTD PMID:16452108 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA] CTD PMID:7900855 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases activity EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of ALPL protein CTD PMID:11171635 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TNF protein results in increased expression of AQP4 mRNA] CTD PMID:22298391 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions
decreases expression 		EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Ouabain results in increased expression of ATP1B1 mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased expression of ATP1B1 mRNA 		CTD PMID:11204457 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Silicon Dioxide results in increased expression of CD69 protein] CTD PMID:15790520 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT1 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA] CTD PMID:9013560 PMID:16081525 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
increases expression 		EXP [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with Doxorubicin] results in increased expression of EP300 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in increased expression of EP300 protein 		CTD PMID:15767673 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGF2 protein] CTD PMID:15654655 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] CTD PMID:15654655 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of FN1 mRNA] CTD PMID:7945571 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP 		1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Hemin results in increased expression of FOS mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of FOS mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lead results in increased expression of FOS mRNA] 		CTD PMID:1932749 PMID:7945571 PMID:10381381 PMID:10693946 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein]; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein]; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] CTD PMID:23996089 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein] CTD PMID:12755590 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] CTD PMID:26275128 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dimaprit results in increased expression of HRH2 mRNA] CTD PMID:9187264 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein] CTD PMID:11164475 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO 		1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of JUN mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Paraquat results in increased expression of JUN mRNA] 		CTD PMID:7662713 PMID:7945571 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [5,8,11,14-Eicosatetraynoic Acid analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Arachidonic Acid analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [ciprofibrate analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Clofibrate results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [pirinixic acid results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Thapsigargin analog results in increased expression of JUNB mRNA] CTD PMID:1932749 PMID:8764118 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases phosphorylation
multiple interactions 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K1 protein
[1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K1 protein 		CTD PMID:14654170 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
decreases phosphorylation 		ISO [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein 		CTD PMID:14654170 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Mt1a metallothionein 1A multiple interactions
decreases expression 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Copper results in increased activity of MT1 promoter]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased expression of MT1 mRNA 		CTD PMID:11551972 PMID:14576086 PMID:15142038 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA] CTD PMID:18938131 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein] CTD PMID:14678745 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCD protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein] CTD PMID:14678745 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [soluble tachyzoite antigen, Toxoplasma gondii results in increased expression of PTGS2 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [soluble tachyzoite antigen, Toxoplasma gondii results in increased expression of PTGS2 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] CTD PMID:18305957 PMID:18938131 PMID:19063610 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA] CTD PMID:8940178 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of SLC30A1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA] CTD PMID:15142038 NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT1 protein] CTD PMID:11882386 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TERT protein CTD PMID:9434777 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases activity 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TGFB1 protein 		CTD PMID:8940178 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein] CTD PMID:16716901 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		[1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K1 protein; [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein; [TNF protein co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] results in increased activity of NFKB protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TNF protein results in increased expression of AQP4 mRNA] 		CTD PMID:14654170 PMID:22298391 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein multiple interactions ISO [TNF protein co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] results in increased activity of NFKB protein CTD PMID:14654170 NCBI chr 7:110,226,696...110,241,459
Ensembl chr 7:110,225,525...110,241,397 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] CTD PMID:19063610 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
4-chloro-N-[(2S,6R)-2,6-dimethyl-1-piperidinyl]-3-sulfamoylbenzamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sfrp4 secreted frizzled-related protein 4 affects binding ISO Clopamide binds to SFRP4 protein CTD PMID:25019556 NCBI chr17:49,974,532...50,026,448
Ensembl chr17:50,015,812...50,026,395 		JBrowse link
4-hydroxytolbutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [CYP2C55 protein results in increased metabolism of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide CTD PMID:30503582 NCBI chr 1:246,286,341...246,348,607
Ensembl chr 1:246,286,341...246,348,607 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [CYP2C19 protein results in increased hydroxylation of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide CTD PMID:30500380 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 multiple interactions ISO [CYP2C66 protein results in increased metabolism of Tolbutamide] which results in increased chemical synthesis of 4'-hydroxytolbutamide CTD PMID:30503582 NCBI chr 1:246,490,888...246,582,199
Ensembl chr 1:248,272,336...248,309,323 		JBrowse link
5-(2-methylpiperazine-1-sulfonyl)isoquinoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCB11 protein] CTD PMID:16452108 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA] CTD PMID:7900855 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases activity EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of ALPL protein CTD PMID:11171635 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Aqp4 aquaporin 4 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TNF protein results in increased expression of AQP4 mRNA] CTD PMID:22298391 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression
multiple interactions 		EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased expression of ATP1B1 mRNA
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Ouabain results in increased expression of ATP1B1 mRNA] 		CTD PMID:11204457 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549 		JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Silicon Dioxide results in increased expression of CD69 protein] CTD PMID:15790520 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT1 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A1 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA] CTD PMID:9013560 PMID:16081525 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
increases expression 		EXP [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with Doxorubicin] results in increased expression of EP300 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in increased expression of EP300 protein 		CTD PMID:15767673 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGF2 protein] CTD PMID:15654655 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] CTD PMID:15654655 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of FN1 mRNA] CTD PMID:7945571 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO 		1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of FOS mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lead results in increased expression of FOS mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Hemin results in increased expression of FOS mRNA] 		CTD PMID:1932749 PMID:7945571 PMID:10381381 PMID:10693946 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein]; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein]; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] CTD PMID:23996089 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [allyl alcohol results in increased secretion of GPT protein] CTD PMID:12755590 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein] CTD PMID:26275128 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Dimaprit results in increased expression of HRH2 mRNA] CTD PMID:9187264 NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein] CTD PMID:11164475 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP
ISO 		1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Acetaldehyde results in increased expression of JUN mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Paraquat results in increased expression of JUN mRNA] 		CTD PMID:7662713 PMID:7945571 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [5,8,11,14-Eicosatetraynoic Acid analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Arachidonic Acid analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [ciprofibrate analog results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Clofibrate results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [pirinixic acid results in increased expression of JUNB mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Thapsigargin analog results in increased expression of JUNB mRNA] CTD PMID:1932749 PMID:8764118 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions
decreases phosphorylation 		ISO [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K1 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K1 protein 		CTD PMID:14654170 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
decreases phosphorylation 		ISO [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased phosphorylation of MAP2K2 protein 		CTD PMID:14654170 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Mt1a metallothionein 1A decreases expression
multiple interactions 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased expression of MT1 mRNA
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Copper results in increased activity of MT1 promoter]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA] 		CTD PMID:11551972 PMID:14576086 PMID:15142038 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA] CTD PMID:18938131 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCA protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein] CTD PMID:14678745 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Heptachlor affects the localization of PRKCD protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein] CTD PMID:14678745 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [soluble tachyzoite antigen, Toxoplasma gondii results in increased expression of PTGS2 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [soluble tachyzoite antigen, Toxoplasma gondii results in increased expression of PTGS2 protein]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] CTD PMID:18305957 PMID:18938131 PMID:19063610 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA] CTD PMID:8940178 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of SLC30A1 mRNA]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of SLC30A1 mRNA] CTD PMID:15142038 NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT1 protein] CTD PMID:11882386 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [CNTF protein affects the phosphorylation of and affects the activity of STAT3 protein] CTD PMID:11882386 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tert telomerase reverse transcriptase decreases activity ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TERT protein CTD PMID:9434777 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases activity 		ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TGFB1 protein results in increased expression of RARA mRNA]
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of TGFB1 protein 		CTD PMID:8940178 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [tert-Butylhydroperoxide affects the localization of TJP1 protein] CTD PMID:16716901 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		[1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K1 protein; [1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine co-treated with TNF protein] results in decreased phosphorylation of MAP2K2 protein; [TNF protein co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] results in increased activity of NFKB protein
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [TNF protein results in increased expression of AQP4 mRNA] 		CTD PMID:14654170 PMID:22298391 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tonsl tonsoku-like, DNA repair protein multiple interactions ISO [TNF protein co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] results in increased activity of NFKB protein CTD PMID:14654170 NCBI chr 7:110,226,696...110,241,459
Ensembl chr 7:110,225,525...110,241,397 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] CTD PMID:19063610 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
acetazolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Acetazolamide results in increased expression of ABCA1 mRNA CTD PMID:19274763 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Akap17a A-kinase anchoring protein 17A increases expression ISO Acetazolamide results in increased expression of AKAP17B mRNA CTD PMID:19274763 NCBI chr12:21,424,202...21,428,308
Ensembl chr12:21,424,202...21,428,247 		JBrowse link
G Akap9 A-kinase anchoring protein 9 increases expression ISO Acetazolamide results in increased expression of AKAP9 mRNA CTD PMID:19274763 NCBI chr 4:31,011,475...31,147,338
Ensembl chr 4:31,011,475...31,147,338 		JBrowse link
G Ammecr1l AMMECR1 like increases expression ISO Acetazolamide results in increased expression of AMMECR1L mRNA CTD PMID:19274763 NCBI chr18:23,661,649...23,685,391
Ensembl chr18:23,661,341...23,685,649 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A increases expression ISO Acetazolamide results in increased expression of ANP32A mRNA CTD PMID:19274763 NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922 		JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Acetazolamide results in decreased expression of AQP1 protein CTD PMID:17219999 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 affects expression ISO Acetazolamide affects the expression of ARHGAP45 mRNA CTD PMID:25811541 NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890 		JBrowse link
G Arid2 AT-rich interaction domain 2 increases expression ISO Acetazolamide results in increased expression of ARID2 mRNA CTD PMID:19274763 NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:129,324,137...129,443,187 		JBrowse link
G Brd4 bromodomain containing 4 increases expression ISO Acetazolamide results in increased expression of BRD4 mRNA CTD PMID:19274763 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Ca1 carbonic anhydrase 1 multiple interactions
decreases activity 		ISO Acetazolamide binds to and results in decreased activity of CA1 protein; Indomethacin inhibits the reaction [Acetazolamide results in decreased activity of CA1 protein] CTD PMID:11430635 PMID:17826101 PMID:19231207 PMID:28117934 PMID:28251759 More... NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca12 carbonic anhydrase 12 decreases activity
multiple interactions 		ISO Acetazolamide results in decreased activity of CA12 protein
Acetazolamide binds to and results in decreased activity of CA12 protein 		CTD PMID:21851094 PMID:28251759 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465 		JBrowse link
G Ca13 carbonic anhydrase 13 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA13 protein CTD PMID:28251759 NCBI chr 2:88,649,643...88,680,763
Ensembl chr 2:88,649,625...88,680,763 		JBrowse link
G Ca14 carbonic anhydrase 14 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA14 protein CTD PMID:28251759 NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Ca4 carbonic anhydrase 4 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA4 protein CTD PMID:28251759 NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916 		JBrowse link
G Ca5a carbonic anhydrase 5A multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA5A protein CTD PMID:28251759 NCBI chr19:66,881,678...66,911,486
Ensembl chr19:66,881,693...66,911,486 		JBrowse link
G Ca5b carbonic anhydrase 5B multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA5B protein CTD PMID:28251759 NCBI chr  X:34,106,553...34,166,651
Ensembl chr  X:34,067,403...34,166,653 		JBrowse link
G Ca6 carbonic anhydrase 6 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA6 protein CTD PMID:28251759 NCBI chr 5:165,941,028...165,959,566
Ensembl chr 5:165,941,029...165,959,566 		JBrowse link
G Ca9 carbonic anhydrase 9 decreases activity
multiple interactions 		ISO Acetazolamide results in decreased activity of CA9 protein
Acetazolamide binds to and results in decreased activity of CA9 protein 		CTD PMID:21851094 PMID:28251759 NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity 		ISO Acetazolamide binds to and results in decreased activity of CA2 protein; Indomethacin inhibits the reaction [Acetazolamide results in decreased activity of CA2 protein] CTD PMID:11430635 PMID:16858005 PMID:17826101 PMID:19231207 PMID:21851094 More... NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO Acetazolamide binds to and results in decreased activity of CA7 protein CTD PMID:28251759 NCBI chr19:435,520...444,927
Ensembl chr19:435,522...452,384 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Acetazolamide promotes the reaction [bleomycetin results in increased activity of CASP3 protein] CTD PMID:21040473 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cbx3 chromobox 3 increases expression ISO Acetazolamide results in increased expression of CBX3 mRNA CTD PMID:19274763 NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911 		JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Acetazolamide results in increased expression of CCND2 mRNA CTD PMID:19274763 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Cd47 Cd47 molecule increases expression ISO Acetazolamide results in increased expression of CD47 mRNA CTD PMID:19274763 NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272 		JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Acetazolamide results in increased expression of CIRBP mRNA CTD PMID:19274763 NCBI chr 7:10,184,515...10,189,623 JBrowse link
G Clcn3 chloride voltage-gated channel 3 increases expression ISO Acetazolamide results in increased expression of CLCN3 mRNA CTD PMID:19274763 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked increases expression ISO Acetazolamide results in increased expression of DDX3X mRNA CTD PMID:19274763 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:12,152,346...12,165,983 		JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression ISO Acetazolamide results in increased expression of DDX6 mRNA CTD PMID:19274763 NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977 		JBrowse link
G Dsc2 desmocollin 2 increases expression ISO Acetazolamide results in increased expression of DSC2 mRNA CTD PMID:19274763 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466 		JBrowse link
G Glg1 golgi glycoprotein 1 increases expression ISO Acetazolamide results in increased expression of GLG1 mRNA CTD PMID:19274763 NCBI chr19:56,034,248...56,133,538
Ensembl chr19:56,006,459...56,133,528 		JBrowse link
G Glul glutamate-ammonia ligase increases expression ISO Acetazolamide results in increased expression of GLUL mRNA CTD PMID:19274763 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520 		JBrowse link
G Htra1 HtrA serine peptidase 1 increases expression ISO Acetazolamide results in increased expression of HTRA1 mRNA CTD PMID:19274763 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Acetazolamide results in increased expression of IGF1R mRNA CTD PMID:19274763 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression ISO Acetazolamide results in increased expression of ITPR2 mRNA CTD PMID:19274763 NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763 		JBrowse link
G Mab21l2 mab-21 like 2 decreases expression ISO Acetazolamide results in decreased expression of MAB21L2 mRNA CTD PMID:19274763 NCBI chr 2:174,244,538...174,247,620
Ensembl chr 2:174,238,828...174,252,064 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Acetazolamide results in increased expression of MAP3K1 mRNA CTD PMID:19274763 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Mt1a metallothionein 1A decreases expression ISO Acetazolamide results in decreased expression of MT1 mRNA CTD PMID:19274763 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit increases expression ISO Acetazolamide results in increased expression of NAA15 mRNA CTD PMID:19274763 NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Acetazolamide results in increased expression of NDRG1 mRNA CTD PMID:19274763 NCBI chr 7:100,573,526...100,614,902
Ensembl chr 7:100,573,523...100,614,913 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO Acetazolamide results in increased expression of NRIP1 mRNA CTD PMID:19274763 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353 		JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Acetazolamide results in increased expression of PEG3 mRNA CTD PMID:19274763 NCBI chr 1:76,130,965...76,157,774
Ensembl chr 1:76,130,948...76,157,743 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 increases expression ISO Acetazolamide results in increased expression of POU2F1 mRNA CTD PMID:19274763 NCBI chr13:80,653,602...80,796,279
Ensembl chr13:80,663,714...80,796,356 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B increases expression ISO Acetazolamide results in increased expression of PPM1B mRNA CTD PMID:19274763 NCBI chr 6:15,399,559...15,460,301
Ensembl chr 6:15,399,562...15,460,756 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha increases expression ISO Acetazolamide results in increased expression of PPP3CA mRNA CTD PMID:19274763 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Rbm39 RNA binding motif protein 39 increases expression ISO Acetazolamide results in increased expression of RBM39 mRNA CTD PMID:19274763 NCBI chr 3:165,123,087...165,156,453
Ensembl chr 3:165,123,095...165,149,397 		JBrowse link
G Rbmx RNA binding motif protein, X-linked increases expression ISO Acetazolamide results in increased expression of RBMX mRNA CTD PMID:19274763 NCBI chr  X:140,342,544...140,352,121
Ensembl chr  X:140,345,571...140,352,035 		JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO Acetazolamide results in increased expression of SATB1 mRNA CTD PMID:19274763 NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,917,215...4,989,925 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Acetazolamide results in increased expression of SC5D mRNA CTD PMID:19274763 NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277 		JBrowse link
G Schip1 schwannomin interacting protein 1 increases expression ISO Acetazolamide results in increased expression of SCHIP1 mRNA CTD PMID:19274763 NCBI chr 2:154,437,217...155,198,560
Ensembl chr 2:155,060,798...155,198,557 		JBrowse link
G Sdc4 syndecan 4 increases expression ISO Acetazolamide results in increased expression of SDC4 mRNA CTD PMID:19274763 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
G Sema4b semaphorin 4B increases expression ISO Acetazolamide results in increased expression of SEMA4B mRNA CTD PMID:19274763 NCBI chr 1:143,545,727...143,587,037
Ensembl chr 1:143,537,690...143,587,037 		JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 increases expression ISO Acetazolamide results in increased expression of SF3B1 mRNA CTD PMID:19274763 NCBI chr 9:63,986,829...64,026,723
Ensembl chr 9:63,986,829...64,026,719 		JBrowse link
G Sfmbt2 Scm-like with four mbt domains 2 increases expression ISO Acetazolamide results in increased expression of SFMBT2 mRNA CTD PMID:19274763 NCBI chr17:72,844,037...73,038,599
Ensembl chr17:72,845,708...73,032,172 		JBrowse link
G Shox2 SHOX homeobox 2 increases expression ISO Acetazolamide results in increased expression of SHOX2 mRNA CTD PMID:19274763 NCBI chr 2:153,524,324...153,537,571
Ensembl chr 2:153,527,571...153,537,161 		JBrowse link
G Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 increases expression ISO Acetazolamide results in increased expression of SMARCC1 mRNA CTD PMID:19274763 NCBI chr 8:118,986,917...119,093,161
Ensembl chr 8:118,989,516...119,093,152 		JBrowse link
G Stx3 syntaxin 3 increases expression ISO Acetazolamide results in increased expression of STX3 mRNA CTD PMID:19274763 NCBI chr 1:217,940,697...218,114,865
Ensembl chr 1:217,909,169...218,110,466 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein increases expression ISO Acetazolamide results in increased expression of STYX mRNA CTD PMID:19274763 NCBI chr15:21,043,738...21,075,515 JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein increases expression ISO Acetazolamide results in increased expression of TIA1 mRNA CTD PMID:19274763 NCBI chr 4:120,410,180...120,440,676
Ensembl chr 4:120,410,251...120,440,665 		JBrowse link
G Tmem30b transmembrane protein 30B increases expression ISO Acetazolamide results in increased expression of TMEM30B mRNA CTD PMID:19274763 NCBI chr 6:97,987,471...97,990,546
Ensembl chr 6:97,987,130...97,991,170 		JBrowse link
G Trim25 tripartite motif-containing 25 increases expression ISO Acetazolamide results in increased expression of TRIM25 mRNA CTD PMID:19274763 NCBI chr10:74,310,024...74,328,473
Ensembl chr10:74,310,022...74,331,716 		JBrowse link
G Umod uromodulin increases expression ISO Acetazolamide results in increased expression of UMOD protein CTD PMID:2655449 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:183,247,674...183,261,030 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 increases expression ISO Acetazolamide results in increased expression of WNK1 mRNA CTD PMID:19274763 NCBI chr 4:154,800,590...154,926,147
Ensembl chr 4:154,800,590...154,926,147 		JBrowse link
G Zfp322a zinc finger protein 322a increases expression ISO Acetazolamide results in increased expression of ZFP322A mRNA CTD PMID:19274763 NCBI chr17:42,201,989...42,216,060
Ensembl chr17:42,200,956...42,279,388 		JBrowse link
acetohexamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Acetohexamide binds to ALB protein; Acetohexamide binds to ALB protein modified form CTD PMID:20435530 PMID:20829128 PMID:20956006 PMID:20974553 PMID:21612784 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases metabolic processing ISO DHRS3 protein results in increased metabolism of Acetohexamide CTD PMID:25451588 NCBI chr 5:162,031,853...162,065,655
Ensembl chr 5:162,031,386...162,065,653 		JBrowse link
almotriptan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases methylation
increases metabolic processing
increases hydroxylation 		ISO CYP1A1 protein results in decreased methylation of almotriptan
CYP1A1 protein results in increased metabolism of almotriptan
CYP1A1 protein results in increased hydroxylation of almotriptan 		CTD PMID:12642466 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases methylation ISO CYP1A2 protein results in decreased methylation of almotriptan CTD PMID:12642466 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases methylation ISO CYP2C19 protein results in decreased methylation of almotriptan CTD PMID:12642466 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases methylation ISO CYP2C8 protein results in decreased methylation of almotriptan CTD PMID:12642466
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases methylation
increases hydroxylation 		ISO CYP2D6 protein results in decreased methylation of almotriptan
CYP2D6 protein results in increased hydroxylation of almotriptan 		CTD PMID:12642466 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases hydroxylation
decreases methylation 		ISO CYP3A4 protein results in increased hydroxylation of almotriptan
CYP3A4 protein results in decreased methylation of almotriptan 		CTD PMID:12642466 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases oxidation ISO FMO3 protein results in increased oxidation of almotriptan CTD PMID:12642466 NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B multiple interactions ISO HTR1B affects the reaction [almotriptan inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11134654 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:91,052,432...91,418,583 		JBrowse link
G Maoa monoamine oxidase A increases metabolic processing ISO MAOA protein results in increased metabolism of almotriptan CTD PMID:12642466 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
amosulalol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 affects activity EXP amosulalol affects the activity of MAPK1 protein CTD PMID:11693273 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects activity EXP amosulalol affects the activity of MAPK3 protein CTD PMID:11693273 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
amprenavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO amprenavir results in decreased activity of ABCB11 protein CTD PMID:20829430 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
affects binding 		ISO ABCB1 protein results in increased transport of amprenavir
[Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of amprenavir
amprenavir binds to ABCB1 protein 		CTD PMID:23976943 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO amprenavir results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO amprenavir results in increased expression of CCL3 protein CTD PMID:17668557 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO amprenavir results in decreased activity of CYP3A4 protein CTD PMID:15523003 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir] CTD PMID:18799805 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
amsacrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin affects binding ISO Amsacrine analog binds to ALB protein; Amsacrine binds to ALB protein CTD PMID:10803926 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Ar androgen receptor multiple interactions ISO Amsacrine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Atg7 autophagy related 7 decreases expression ISO Amsacrine results in decreased expression of ATG7 protein CTD PMID:37451322 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO ATM protein promotes the reaction [Amsacrine results in increased phosphorylation of H2AX protein] CTD PMID:37451322 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases response to substance ISO BAX protein results in increased susceptibility to Amsacrine CTD PMID:16177561 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance ISO BCL2 protein results in decreased susceptibility to Amsacrine CTD PMID:10920913 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions 		ISO Amsacrine results in decreased expression of BCL2L1 protein
[[Amsacrine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; [[Amsacrine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; ELAVL1 protein inhibits the reaction [Amsacrine results in decreased expression of BCL2L1 mRNA]; ELAVL1 protein inhibits the reaction [Amsacrine results in increased degradation of BCL2L1 mRNA] 		CTD PMID:37451322 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Becn1 beclin 1 increases expression ISO Amsacrine results in increased expression of BECN1 protein CTD PMID:37451322 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Casp2 caspase 2 increases splicing
increases expression 		ISO Amsacrine results in increased splicing of CASP2 mRNA
Amsacrine results in increased expression of CASP2 mRNA alternative form 		CTD PMID:14757846 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO Amsacrine results in increased degradation of and results in decreased expression of CCNA2 protein CTD PMID:11774253 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO Amsacrine results in increased degradation of and results in decreased expression of CCNB1 protein CTD PMID:11774253 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO Amsacrine results in increased expression of CCNE1 protein CTD PMID:11774253 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Amsacrine CTD PMID:16969495 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 decreases expression
multiple interactions 		ISO Amsacrine results in decreased expression of ELAVL1 protein
[[Amsacrine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; [[Amsacrine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; [Amsacrine results in increased expression of MIR22] which results in decreased expression of ELAVL1 mRNA; Amsacrine results in decreased expression of and results in decreased stability of ELAVL1 mRNA; ELAVL1 protein inhibits the reaction [Amsacrine results in decreased expression of BCL2L1 mRNA]; ELAVL1 protein inhibits the reaction [Amsacrine results in increased degradation of BCL2L1 mRNA]; GLX351322 inhibits the reaction [Amsacrine results in decreased expression of ELAVL1 protein] 		CTD PMID:37451322 NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Amsacrine binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
multiple interactions 		ISO Amsacrine results in increased phosphorylation of H2AX protein
ATM protein promotes the reaction [Amsacrine results in increased phosphorylation of H2AX protein] 		CTD PMID:37451322 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Amsacrine binds to and results in decreased activity of KCNH2 protein CTD PMID:15148258 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Amsacrine results in increased expression of MAP1LC3B protein CTD PMID:37451322 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [Amsacrine results in increased expression of MIR22 protein] CTD PMID:37451322 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation 		ISO [[Amsacrine results in decreased phosphorylation of MAPK1 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; GLX351322 inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK1 protein]; MAP2K1 protein inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK1 protein]; MitoTEMPO inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK1 protein] CTD PMID:37451322 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 increases activity
affects response to substance
multiple interactions 		ISO Amsacrine results in increased activity of MAPK12 protein
MAPK12 protein affects the susceptibility to Amsacrine
[MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Amsacrine; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Amsacrine 		CTD PMID:21878638 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions 		ISO Amsacrine results in decreased phosphorylation of MAPK3 protein
[[Amsacrine results in decreased phosphorylation of MAPK3 protein] which results in decreased expression of ELAVL1 mRNA] which results in increased degradation of BCL2L1 mRNA; GLX351322 inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK3 protein]; MitoTEMPO inhibits the reaction [Amsacrine results in decreased phosphorylation of MAPK3 protein] 		CTD PMID:37451322 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mdm2 MDM2 proto-oncogene decreases response to substance ISO MDM2 promoter SNP results in decreased susceptibility to Amsacrine CTD PMID:17575151 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Mir22 microRNA 22 increases expression
multiple interactions 		ISO Amsacrine results in increased expression of MIR22
[Amsacrine results in increased expression of MIR22] which results in decreased expression of ELAVL1 mRNA; MAP2K1 protein inhibits the reaction [Amsacrine results in increased expression of MIR22 protein] 		CTD PMID:37451322 NCBI chr10:60,805,331...60,805,425
Ensembl chr10:60,805,331...60,805,425 		JBrowse link
G Mir25 microRNA 25 decreases expression
multiple interactions 		ISO Amsacrine results in decreased expression of MIR25
SIDT2 protein promotes the reaction [Amsacrine results in decreased expression of MIR25 protein] 		CTD PMID:37451322 NCBI chr12:22,156,641...22,156,724 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Amsacrine results in decreased expression of MYC mRNA CTD PMID:11585056 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Ncl nucleolin affects response to substance ISO NCL protein affects the susceptibility to Amsacrine CTD PMID:16600179 NCBI chr 9:94,447,559...94,456,083
Ensembl chr 9:94,446,682...94,456,083 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression
multiple interactions 		ISO Amsacrine results in increased expression of NOX4 protein
Amsacrine results in increased expression of and results in decreased degradation of NOX4 mRNA; SIDT2 protein promotes the reaction [Amsacrine results in increased expression of NOX4 mRNA]; SIDT2 protein promotes the reaction [Amsacrine results in increased expression of NOX4 protein] 		CTD PMID:37451322 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Amsacrine binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Amsacrine results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012 		JBrowse link
G Rad51 RAD51 recombinase affects response to substance ISO RAD51 protein affects the susceptibility to Amsacrine CTD PMID:16600179 NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Amsacrine results in increased expression of RARB mRNA alternative form CTD PMID:17608728 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 multiple interactions
increases expression 		ISO SIDT2 protein promotes the reaction [Amsacrine results in decreased expression of MIR25 protein]; SIDT2 protein promotes the reaction [Amsacrine results in increased expression of NOX4 mRNA]; SIDT2 protein promotes the reaction [Amsacrine results in increased expression of NOX4 protein]
Amsacrine results in increased expression of SIDT2 protein 		CTD PMID:37451322 NCBI chr 8:55,129,091...55,146,446
Ensembl chr 8:55,129,091...55,145,408 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Amsacrine binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO Amsacrine results in increased expression of TNFRSF11B mRNA CTD PMID:11459812 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Amsacrine results in decreased expression of TNFSF11 mRNA CTD PMID:11459812 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
affects response to substance
decreases response to substance 		ISO [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Amsacrine; [MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Amsacrine; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Amsacrine
TOP2A protein modified form affects the susceptibility to Amsacrine
TOP2A gene mutant form results in decreased susceptibility to Amsacrine; TOP2A protein mutant form results in decreased susceptibility to Amsacrine 		CTD PMID:1651812 PMID:10727526 PMID:11470519 PMID:11676865 PMID:12569090 More... NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Top2b DNA topoisomerase II beta decreases response to substance ISO TOP2B protein mutant form results in decreased susceptibility to Amsacrine CTD PMID:15322234 PMID:16239602 PMID:16549872 NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464 		JBrowse link
G Tp53 tumor protein p53 increases activity
increases glutathionylation
multiple interactions
increases expression 		ISO Amsacrine analog results in increased activity of TP53 protein
Amsacrine results in increased glutathionylation of TP53 protein
Amsacrine results in increased stability of and results in increased activity of TP53 protein
Amsacrine results in increased expression of TP53 protein 		CTD PMID:11774253 PMID:12082016 PMID:16177561 PMID:17555331 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Amsacrine results in increased expression of TP53I3 mRNA CTD PMID:17374387 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO Amsacrine results in decreased expression of UBE2C mRNA CTD PMID:17374387 NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:173,925,934...173,932,678 		JBrowse link
G Wrn WRN RecQ like helicase increases response to substance ISO WRN gene mutant form results in increased susceptibility to Amsacrine CTD PMID:10725663 NCBI chr16:65,466,552...65,602,951
Ensembl chr16:65,456,254...65,602,951 		JBrowse link
Apratastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdc1 syndecan 1 decreases secretion ISO apratastat results in decreased secretion of SDC1 protein CTD PMID:19875451 NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:37,297,010...37,304,500 		JBrowse link
G Sdc4 syndecan 4 decreases secretion ISO apratastat results in decreased secretion of SDC4 protein CTD PMID:19875451 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
argatroban term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ACTA2 protein] CTD PMID:22841818 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ADGRE1 mRNA] CTD PMID:22841818 NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; argatroban inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein] CTD PMID:22841818 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of CD68 mRNA] CTD PMID:22841818 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA] CTD PMID:22841818 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO argatroban affects the reaction [Dietary Fats results in increased expression of CXCL2 mRNA] CTD PMID:22841818 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of F2 protein]
argatroban binds to and results in decreased activity of F2 protein 		CTD PMID:15080313 PMID:16084352 PMID:18449412 PMID:22841818 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of ICAM1 mRNA] CTD PMID:22841818 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Cholesterol]; argatroban inhibits the reaction [[LDLR gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Triglycerides] CTD PMID:22841818 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO argatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA] CTD PMID:22841818 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
azosemide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc12a2 solute carrier family 12 member 2 decreases activity
multiple interactions 		ISO azosemide results in decreased activity of SLC12A2 protein
azosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium] 		CTD PMID:15517342 PMID:29959396 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
baricitinib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aak1 AP2 associated kinase 1 decreases activity ISO baricitinib results in decreased activity of AAK1 protein CTD PMID:32113509 NCBI chr 4:120,845,012...121,009,170
Ensembl chr 4:120,858,557...121,004,236 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO baricitinib inhibits the reaction [OSM protein results in increased expression of CCL2 mRNA] CTD PMID:23968543 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Gak cyclin G associated kinase decreases activity ISO baricitinib results in decreased activity of GAK protein CTD PMID:32113509 NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO baricitinib inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of ID2 protein] CTD PMID:32428222 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961 		JBrowse link
G Jak1 Janus kinase 1 decreases activity
multiple interactions 		ISO baricitinib results in decreased activity of JAK1 protein
baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK1 protein] 		CTD PMID:23968543 PMID:29687421 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 decreases activity
multiple interactions 		ISO baricitinib results in decreased activity of JAK2 protein
baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK2 protein] 		CTD PMID:23968543 PMID:29687421 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK3 protein] CTD PMID:23968543 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,420,415...18,433,222 		JBrowse link
G Osm oncostatin M multiple interactions ISO baricitinib inhibits the reaction [OSM protein results in increased expression of CCL2 mRNA]; baricitinib inhibits the reaction [OSM protein results in increased expression of SAA1 mRNA]; baricitinib inhibits the reaction [OSM protein results in increased expression of SAA2 mRNA]; baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK1 protein]; baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; baricitinib inhibits the reaction [OSM protein results in increased phosphorylation of and results in increased activity of JAK3 protein] CTD PMID:23968543 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO baricitinib inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased phosphorylation of STAT1 protein] CTD PMID:32428222 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
belinostat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO belinostat results in decreased expression of ABCC6 mRNA CTD PMID:27188386 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression ISO belinostat results in decreased expression of ABL1 mRNA CTD PMID:19606018 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO belinostat results in decreased expression of ACACB mRNA CTD PMID:27188386 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain increases expression ISO belinostat results in increased expression of ACADSB mRNA CTD PMID:26272509 NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO belinostat results in increased expression of ACKR3 mRNA CTD PMID:27188386 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases expression ISO belinostat results in decreased expression of ACP5 mRNA CTD PMID:27188386 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO belinostat results in decreased expression of ACSL5 mRNA CTD PMID:27188386 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACSM3 mRNA CTD PMID:27188386 NCBI chr 1:183,564,652...183,591,328
Ensembl chr 1:183,564,635...183,591,437 		JBrowse link
G Ada adenosine deaminase decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ADA mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adam12 ADAM metallopeptidase domain 12 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ADAM12 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADAM12 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:198,116,968...198,443,680
Ensembl chr 1:198,116,975...198,447,552 		JBrowse link
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA CTD PMID:27188386 NCBI chr 8:37,566,064...37,589,446
Ensembl chr 8:37,566,065...37,589,446 		JBrowse link
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 decreases expression ISO belinostat results in decreased expression of ADAMTS3 mRNA CTD PMID:27188386 NCBI chr14:18,515,249...18,721,887
Ensembl chr14:18,515,249...18,721,887 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of ADCYAP1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADCYAP1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADGRG1 mRNA
belinostat results in decreased expression of ADGRG1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ADGRL3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADGRL3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418 		JBrowse link
G Adi1 acireductone dioxygenase 1 decreases expression ISO belinostat results in decreased expression of ADI1 mRNA CTD PMID:27188386 NCBI chr 6:51,035,267...51,042,229
Ensembl chr 6:51,034,931...51,042,855 		JBrowse link
G Afp alpha-fetoprotein decreases expression ISO belinostat results in decreased expression of AFP mRNA CTD PMID:26272509 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649 		JBrowse link
G Ak7 adenylate kinase 7 increases expression ISO belinostat results in increased expression of AK7 mRNA CTD PMID:27188386 NCBI chr 6:130,376,499...130,444,674
Ensembl chr 6:130,376,550...130,444,677 		JBrowse link
G Akna AT-hook transcription factor decreases expression ISO belinostat results in decreased expression of AKNA mRNA CTD PMID:27188386 NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO belinostat results in increased phosphorylation of AKT1 protein CTD PMID:23671600 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression ISO belinostat results in decreased expression of ALDOB mRNA CTD PMID:27188386 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression ISO belinostat results in decreased expression of AMPD3 mRNA CTD PMID:27188386 NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608 		JBrowse link
G Angpt1 angiopoietin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of ANGPT1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Angpt2 angiopoietin 2 decreases expression ISO belinostat results in decreased expression of ANGPT2 mRNA CTD PMID:27188386 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239 		JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ANKS1B mRNA CTD PMID:27188386 NCBI chr 7:26,200,649...27,366,552
Ensembl chr 7:26,201,240...27,364,943 		JBrowse link
G Ano3 anoctamin 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of ANO3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANO3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:117,690,242...118,004,695
Ensembl chr 3:117,692,103...118,004,675 		JBrowse link
G Anxa2 annexin A2 increases expression
multiple interactions 		ISO belinostat results in increased expression of ANXA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631 		JBrowse link
G Anxa4 annexin A4 decreases expression ISO belinostat results in decreased expression of ANXA4 mRNA CTD PMID:27188386 NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513 		JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression ISO belinostat results in decreased expression of AOX1 mRNA CTD PMID:27188386 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 increases expression ISO belinostat results in increased expression of AP5M1 mRNA CTD PMID:26272509 NCBI chr15:24,835,122...24,864,854
Ensembl chr15:24,835,100...24,862,606 		JBrowse link
G Apela apelin receptor early endogenous ligand increases expression ISO belinostat results in increased expression of APELA mRNA CTD PMID:26272509 NCBI chr16:29,460,855...29,469,962
Ensembl chr16:29,460,812...29,469,955 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO belinostat results in decreased expression of APOC1 mRNA CTD PMID:27188386 NCBI chr 1:88,475,018...88,479,052
Ensembl chr 1:88,474,663...88,478,155 		JBrowse link
G Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 decreases expression ISO belinostat results in decreased expression of ARAP3 mRNA CTD PMID:27188386 NCBI chr18:30,058,739...30,085,415
Ensembl chr18:30,058,275...30,084,865 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 increases expression
multiple interactions 		ISO belinostat results in increased expression of ARHGAP24 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARHGAP24 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950 		JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ARHGEF37 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGEF37 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:57,205,621...57,271,284
Ensembl chr18:57,230,117...57,271,031 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 decreases expression ISO belinostat results in decreased expression of ARHGEF4 mRNA CTD PMID:27188386 NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550 		JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARNT2 mRNA CTD PMID:27188386 NCBI chr 1:147,645,354...147,801,986
Ensembl chr 1:147,599,058...147,801,997 		JBrowse link
G Arrb1 arrestin, beta 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of ARRB1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARRB1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO belinostat results in decreased expression of ASGR1 mRNA CTD PMID:27188386 NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO belinostat results in decreased expression of ASNS mRNA CTD PMID:27188386 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Astn1 astrotactin 1 decreases expression ISO belinostat results in decreased expression of ASTN1 mRNA CTD PMID:26272509 NCBI chr13:73,070,754...73,388,902
Ensembl chr13:73,071,267...73,388,895 		JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 increases expression
multiple interactions 		ISO belinostat results in increased expression of ATP8B1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATP8B1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027 		JBrowse link
G Aurka aurora kinase A decreases expression
decreases activity 		ISO belinostat results in decreased expression of AURKA mRNA; belinostat results in decreased expression of AURKA protein
belinostat results in decreased activity of AURKA protein 		CTD PMID:19606018 NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:181,546,742...181,562,771 		JBrowse link
G Aurkb aurora kinase B decreases activity
decreases expression 		ISO belinostat results in decreased activity of AURKB protein
belinostat results in decreased expression of AURKB mRNA; belinostat results in decreased expression of AURKB protein 		CTD PMID:19606018 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Aven apoptosis and caspase activation inhibitor decreases expression ISO belinostat results in decreased expression of AVEN mRNA CTD PMID:27188386 NCBI chr 3:119,753,395...119,886,009
Ensembl chr 3:119,872,661...119,886,008 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) decreases expression ISO belinostat results in decreased expression of B3GALNT1 mRNA CTD PMID:27188386 NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of B3GNT5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of B3GNT5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:94,645,480...94,657,584
Ensembl chr11:94,645,480...94,660,514 		JBrowse link
G Bag2 BAG cochaperone 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BAG2 mRNA
belinostat results in increased expression of BAG2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:43,465,993...43,476,637
Ensembl chr 9:43,465,995...43,476,752 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BAMBI mRNA CTD PMID:27188386 NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247 		JBrowse link
G Bbs9 Bardet-Biedl syndrome 9 increases expression
multiple interactions 		ISO belinostat results in increased expression of BBS9 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BBS9 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:29,288,846...29,713,889
Ensembl chr 8:29,289,997...29,713,880 		JBrowse link
G Bcl11a BCL11 transcription factor A increases expression
multiple interactions 		ISO belinostat results in increased expression of BCL11A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:102,230,147...102,325,289
Ensembl chr14:102,231,113...102,325,623 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO belinostat results in decreased expression of BCL2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO belinostat results in increased expression of BCL2L11 protein CTD PMID:18223231 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO belinostat results in decreased expression of BCLAF1 mRNA CTD PMID:19606018 NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:16,914,118...16,936,801 		JBrowse link
G Bex5l1 brain expressed X-linked 5 like 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of BEX5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BEX5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:119,181,370...119,202,904 JBrowse link
G Bfsp1 beaded filament structural protein 1 decreases expression ISO belinostat results in decreased expression of BFSP1 mRNA CTD PMID:27188386 NCBI chr 3:151,648,588...151,706,153
Ensembl chr 3:151,648,588...151,682,837 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO belinostat results in decreased expression of BIRC5 mRNA CTD PMID:19606018 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmp5 bone morphogenetic protein 5 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP5 mRNA
belinostat results in increased expression of BMP5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:85,397,629...85,520,374
Ensembl chr 8:85,396,925...85,520,189 		JBrowse link
G Bmper BMP-binding endothelial regulator increases expression
multiple interactions 		ISO belinostat results in increased expression of BMPER mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMPER mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:30,008,049...30,253,201
Ensembl chr 8:30,008,148...30,434,359 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO belinostat results in decreased expression of BMPR1B mRNA CTD PMID:26272509 NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:233,211,525...233,544,311 		JBrowse link
G Bnc2 basonuclin zinc finger protein 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BNC2 mRNA
belinostat results in increased expression of BNC2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:103,724,934...104,061,890
Ensembl chr 5:103,724,934...104,125,428 		JBrowse link
G Borcs8 BLOC-1 related complex subunit 8 increases expression
multiple interactions 		ISO belinostat results in increased expression of BORCS8 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BORCS8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr16:19,308,247...19,314,910
Ensembl chr16:19,308,247...19,314,963 		JBrowse link
G Bspry B-box and SPRY domain containing multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA CTD PMID:27188386 NCBI chr 5:80,942,974...80,965,157
Ensembl chr 5:80,942,979...80,988,154 		JBrowse link
G C1h10orf143 similar to human chromosome 10 open reading frame 143 decreases expression ISO belinostat results in decreased expression of C10ORF143 mRNA CTD PMID:27188386 NCBI chr 1:201,614,151...201,654,142
Ensembl chr 1:201,561,396...201,652,127 		JBrowse link
G C1h19orf33 similar to human chromosome 19 open reading frame 33 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C19ORF33 mRNA CTD PMID:27188386 NCBI chr 1:93,677,305...93,678,141
Ensembl chr 1:93,677,305...93,678,141 		JBrowse link
G C2h4orf33 similar to human chromosome 4 open reading frame 33 increases expression ISO belinostat results in increased expression of C4ORF33 mRNA CTD PMID:27188386 NCBI chr 2:126,692,176...126,769,183
Ensembl chr 2:126,697,854...126,746,878 		JBrowse link
G C3h11orf96 similar to human chromosome 11 open reading frame 96 increases expression
multiple interactions 		ISO belinostat results in increased expression of C11ORF96 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C11ORF96 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:100,375,474...100,376,717
Ensembl chr 3:100,351,199...100,378,346 		JBrowse link
G C5h8orf34 similar to human chromosome 8 open reading frame 34 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C8ORF34 mRNA
belinostat results in increased expression of C8ORF34 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:12,021,000...12,560,212
Ensembl chr 5:12,021,007...12,559,772 		JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression ISO belinostat results in decreased expression of CA4 mRNA CTD PMID:27188386 NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916 		JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression ISO belinostat results in decreased expression of CABLES1 mRNA CTD PMID:27188386 NCBI chr18:3,349,681...3,455,956
Ensembl chr18:3,351,652...3,455,956 		JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase decreases expression ISO belinostat results in decreased expression of CAD mRNA CTD PMID:19606018 NCBI chr 6:31,012,091...31,035,098
Ensembl chr 6:31,012,091...31,035,297 		JBrowse link
G Calb1 calbindin 1 increases expression ISO belinostat results in increased expression of CALB1 mRNA CTD PMID:26272509 NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160 		JBrowse link
G Calhm6 calcium homeostasis modulator family member 6 decreases expression ISO belinostat results in decreased expression of CALHM6 mRNA CTD PMID:27188386 NCBI chr20:26,638,721...26,640,466
Ensembl chr20:26,638,722...26,640,408 		JBrowse link
G Calml4 calmodulin-like 4 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of CALML4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CALML4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:72,218,870...72,230,650
Ensembl chr 8:72,218,613...72,230,650 		JBrowse link
G Caprin1 cell cycle associated protein 1 decreases expression ISO belinostat results in decreased expression of CAPRIN1 mRNA CTD PMID:27188386 NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562 		JBrowse link
G Card10 caspase recruitment domain family, member 10 decreases expression ISO belinostat results in decreased expression of CARD10 mRNA CTD PMID:27188386 NCBI chr 7:112,210,944...112,252,044
Ensembl chr 7:112,210,776...112,239,806 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage 		ISO Bortezomib promotes the reaction [belinostat results in increased cleavage of CASP3 protein] CTD PMID:18223231 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases cleavage ISO belinostat results in increased cleavage of CASP7 protein CTD PMID:25537862 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases expression
multiple interactions 		ISO belinostat results in increased expression of CASP8 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions 		ISO belinostat results in increased cleavage of CASP9 protein
Bortezomib promotes the reaction [belinostat results in increased cleavage of CASP9 protein] 		CTD PMID:18223231 PMID:25537862 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccdc34 coiled-coil domain containing 34 increases expression ISO belinostat results in increased expression of CCDC34 mRNA CTD PMID:27188386 NCBI chr 3:117,007,652...117,042,885
Ensembl chr 3:117,005,760...117,042,226 		JBrowse link
G Ccdc69 coiled-coil domain containing 69 increases expression
multiple interactions 		ISO belinostat results in increased expression of CCDC69 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:39,673,984...39,701,080
Ensembl chr10:39,673,985...39,700,579 		JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
multiple interactions 		ISO belinostat results in decreased expression of CCKBR mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 increases expression
multiple interactions 		ISO belinostat results in increased expression of CCL26 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCL26 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:26,745,972...26,750,924 JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO belinostat results in increased expression of CCN1 mRNA CTD PMID:23671600 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO belinostat results in increased expression of CCN2 mRNA CTD PMID:19606018 PMID:23671600 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO belinostat results in decreased expression of CCNA2 mRNA CTD PMID:19606018 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO belinostat results in decreased expression of CCNB1 mRNA CTD PMID:19606018 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of CCND2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCND2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Cd24 CD24 molecule multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA
belinostat results in increased expression of CD24 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785 		JBrowse link
G Cd9 CD9 molecule increases expression
multiple interactions 		ISO belinostat results in increased expression of CD9 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD9 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:159,942,560...159,975,444 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO belinostat results in decreased expression of CDC25B mRNA CTD PMID:19606018 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO belinostat results in decreased expression of CDC25C mRNA CTD PMID:29733868 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,609,959...26,630,292 		JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of CDH1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDH1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdh18 cadherin 18 increases expression ISO belinostat results in increased expression of CDH18 mRNA CTD PMID:26272509 NCBI chr 2:74,548,681...75,550,720
Ensembl chr 2:75,075,595...75,550,720 		JBrowse link
G Cdh3 cadherin 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of CDH3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDH3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257 		JBrowse link
G Cdh9 cadherin 9 decreases expression
increases expression 		ISO belinostat results in decreased expression of CDH9 mRNA
belinostat results in increased expression of CDH9 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:67,954,708...68,094,371
Ensembl chr 2:67,955,166...68,094,365 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO belinostat results in decreased expression of CDK1 mRNA CTD PMID:19606018 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO belinostat results in decreased expression of CDK4 mRNA CTD PMID:19606018 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression 		ISO belinostat promotes the reaction [decitabine results in increased expression of CDKN1A mRNA]; belinostat promotes the reaction [decitabine results in increased expression of CDKN1A protein]
belinostat results in increased expression of CDKN1A mRNA; belinostat results in increased expression of CDKN1A protein 		CTD PMID:19234609 PMID:19606018 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO belinostat results in decreased expression of CDKN2A mRNA CTD PMID:19606018 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Cdx4 caudal type homeo box 4 decreases expression ISO belinostat results in decreased expression of CDX4 mRNA CTD PMID:27188386 NCBI chr  X:72,392,653...72,401,239
Ensembl chr  X:72,392,653...72,401,239 		JBrowse link
G Cep126 centrosomal protein 126 increases expression
multiple interactions 		ISO belinostat results in increased expression of CEP126 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP126 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:13,485,211...13,552,711
Ensembl chr 8:13,490,685...13,552,221 		JBrowse link
G Cep85l centrosomal protein 85-like increases expression
multiple interactions 		ISO belinostat results in increased expression of CEP85L mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP85L mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr20:33,111,114...33,282,182
Ensembl chr20:33,115,438...33,282,238 		JBrowse link
G Cfap119 cilia and flagella associated protein 119 increases expression ISO belinostat results in increased expression of CFAP119 mRNA CTD PMID:27188386 NCBI chr 1:191,627,662...191,647,429
Ensembl chr 1:191,623,673...191,632,829 		JBrowse link
G Cfap20dc CFAP20 domain containing increases expression ISO belinostat results in increased expression of CFAP20DC mRNA CTD PMID:27188386 NCBI chr15:18,661,562...18,907,226
Ensembl chr15:18,661,508...18,907,225 		JBrowse link
G Cftr CF transmembrane conductance regulator decreases expression ISO belinostat results in decreased expression of CFTR mRNA CTD PMID:27188386 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Chga chromogranin A increases expression
multiple interactions 		ISO belinostat results in increased expression of CHGA mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHGA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237 		JBrowse link
G Chodl chondrolectin multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA
belinostat results in increased expression of CHODL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:31,141,030...31,163,342
Ensembl chr11:31,141,021...31,163,334 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of CHRM3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHRM3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:64,696,549...65,158,622
Ensembl chr17:64,696,066...65,173,304 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit increases expression
multiple interactions 		ISO belinostat results in increased expression of CHRNA3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHRNA3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:64,297,755...64,311,412 		JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO belinostat results in increased expression of CHST15 mRNA CTD PMID:27188386 NCBI chr 1:196,458,978...196,540,088
Ensembl chr 1:196,460,425...196,491,444 		JBrowse link
G Cimap3 ciliary microtubule associated protein 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of CIMAP3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CIMAP3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:196,164,103...196,181,466
Ensembl chr 2:196,163,275...196,181,604 		JBrowse link
G Cldn7 claudin 7 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA
belinostat results in increased expression of CLDN7 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905 		JBrowse link
G Clrn1 clarin 1 increases expression ISO belinostat results in increased expression of CLRN1 mRNA CTD PMID:27188386 NCBI chr 2:145,233,941...145,280,855
Ensembl chr 2:145,233,941...145,280,855 		JBrowse link
G Clrn3 clarin 3 decreases expression ISO belinostat results in decreased expression of CLRN3 mRNA CTD PMID:27188386 NCBI chr 1:199,748,863...199,764,486
Ensembl chr 1:199,748,864...199,764,486 		JBrowse link
G Clu clusterin multiple interactions
increases expression 		ISO belinostat promotes the reaction [decitabine results in increased expression of CLU mRNA]; belinostat promotes the reaction [decitabine results in increased expression of CLU protein]
belinostat results in increased expression of CLU mRNA; belinostat results in increased expression of CLU protein 		CTD PMID:19234609 PMID:19606018 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO belinostat results in decreased expression of CMPK2 mRNA CTD PMID:27188386 NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNKSR2 mRNA CTD PMID:27188386 NCBI chr  X:40,722,843...40,971,730
Ensembl chr  X:40,722,996...40,965,604 		JBrowse link
G Cnmd chondromodulin increases expression
multiple interactions 		ISO belinostat results in increased expression of CNMD mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:61,450,617...61,475,382
Ensembl chr15:61,450,450...61,475,350 		JBrowse link
G Cntn1 contactin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of CNTN1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNTN1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391 		JBrowse link
G Cntn3 contactin 3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of CNTN3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNTN3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:136,397,575...136,770,765
Ensembl chr 4:136,398,572...136,770,717 		JBrowse link
G Cntnap4 contactin associated protein family member 4 decreases expression ISO belinostat results in decreased expression of CNTNAP4 mRNA CTD PMID:27188386 NCBI chr19:57,477,447...57,765,173
Ensembl chr19:57,477,310...57,821,701 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COBL mRNA CTD PMID:27188386 NCBI chr14:91,041,721...91,274,272
Ensembl chr14:91,041,721...91,274,257 		JBrowse link
G Coch cochlin decreases expression ISO belinostat results in decreased expression of COCH mRNA CTD PMID:27188386 NCBI chr 6:74,766,485...74,780,504
Ensembl chr 6:74,766,419...74,780,502 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A2 mRNA
belinostat results in increased expression of COL1A2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain decreases expression ISO belinostat results in decreased expression of COL26A1 mRNA CTD PMID:27188386 NCBI chr12:25,429,362...25,575,205
Ensembl chr12:25,429,387...25,575,206 		JBrowse link
G Col6a6 collagen type VI alpha 6 chain decreases expression ISO belinostat results in decreased expression of COL6A6 mRNA CTD PMID:27188386 NCBI chr 8:115,196,833...115,352,161
Ensembl chr 8:115,197,464...115,352,136 		JBrowse link
G Colec12 collectin sub-family member 12 increases expression ISO belinostat results in increased expression of COLEC12 mRNA CTD PMID:26272509 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297 		JBrowse link
G Colgalt2 collagen beta(1-O)galactosyltransferase 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of COLGALT2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of COLGALT2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:67,073,551...67,178,194
Ensembl chr13:67,073,551...67,178,194 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COMTD1 mRNA
belinostat results in increased expression of COMTD1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232 		JBrowse link
G Cpne2 copine 2 decreases expression ISO belinostat results in decreased expression of CPNE2 mRNA CTD PMID:27188386 NCBI chr19:10,440,245...10,477,783
Ensembl chr19:10,434,647...10,477,783 		JBrowse link
G Cpne4 copine 4 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CPNE4 mRNA
belinostat results in increased expression of CPNE4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:114,056,152...114,531,855
Ensembl chr 8:113,993,703...114,531,855 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like increases expression
multiple interactions 		ISO belinostat results in increased expression of CR1L mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CR1L mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869 		JBrowse link
G Crb1 crumbs cell polarity complex component 1 increases expression ISO belinostat results in increased expression of CRB1 mRNA CTD PMID:27188386 NCBI chr13:53,352,932...53,540,019
Ensembl chr13:53,352,932...53,540,019 		JBrowse link
G Crip1 cysteine rich protein 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRIP1 mRNA
belinostat results in increased expression of CRIP1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:138,047,801...138,055,672 		JBrowse link
G Cripto cripto, EGF-CFC family member increases expression ISO belinostat results in increased expression of CRIPTO mRNA CTD PMID:26272509 NCBI chr 8:119,803,182...119,808,714
Ensembl chr 8:119,803,220...119,808,948 		JBrowse link
G Cryba4 crystallin, beta A4 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of CRYBA4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CRYBA4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:50,039,148...50,053,636
Ensembl chr12:50,047,049...50,053,634 		JBrowse link
G Crybg1 crystallin beta-gamma domain containing 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of CRYBG1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr20:49,007,673...49,204,040
Ensembl chr20:49,007,929...49,204,047 		JBrowse link
G Cthrc1 collagen triple helix repeat containing 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of CTHRC1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTHRC1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:72,007,372...72,017,654
Ensembl chr 7:72,007,372...72,017,654 		JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO belinostat results in decreased expression of CTPS1 mRNA CTD PMID:19606018 NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465 		JBrowse link
G Ctsk cathepsin K decreases expression ISO belinostat results in decreased expression of CTSK mRNA CTD PMID:27188386 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Ctso cathepsin O decreases expression ISO belinostat results in decreased expression of CTSO mRNA CTD PMID:27188386 NCBI chr 2:169,528,468...169,551,975
Ensembl chr 2:169,528,511...169,554,995 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions
decreases expression 		ISO belinostat results in increased expression of CXCL12 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA
belinostat results in decreased expression of CXCL12 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO belinostat results in increased expression of CXCL14 mRNA CTD PMID:26272509 NCBI chr17:8,323,150...8,331,176
Ensembl chr17:8,323,143...8,331,172 		JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 decreases expression ISO belinostat results in decreased expression of CYFIP1 mRNA CTD PMID:27188386 NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO belinostat results in increased expression of CYP1B1 mRNA CTD PMID:26272509 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO belinostat results in increased expression of CYP26A1 mRNA CTD PMID:26272509 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO belinostat results in increased expression of CYP39A1 mRNA CTD PMID:27188386 NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060 		JBrowse link
G Cyth1 cytohesin 1 decreases expression ISO belinostat results in decreased expression of CYTH1 mRNA CTD PMID:27188386 NCBI chr10:103,901,376...103,984,496
Ensembl chr10:103,864,804...103,984,383 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of DACT1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:95,526,645...95,538,625
Ensembl chr 6:95,526,690...95,551,053 		JBrowse link
G Dazl deleted in azoospermia-like multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DAZL mRNA
belinostat results in decreased expression of DAZL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:18,193,363...18,210,100
Ensembl chr 9:18,193,363...18,210,100 		JBrowse link
G Dcaf7 DDB1 and CUL4 associated factor 7 increases expression ISO belinostat results in increased expression of DCAF7 mRNA CTD PMID:27188386 NCBI chr10:91,473,900...91,496,080
Ensembl chr10:91,473,900...91,496,080 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCC mRNA CTD PMID:27188386 NCBI chr18:67,144,272...68,248,159
Ensembl chr18:67,149,179...68,247,541 		JBrowse link
G Dcdc2 doublecortin domain containing 2 decreases expression ISO belinostat results in decreased expression of DCDC2 mRNA CTD PMID:27188386 NCBI chr17:40,274,009...40,459,757
Ensembl chr17:40,274,009...40,458,790 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO belinostat results in decreased expression of DDB2 mRNA CTD PMID:29733868 NCBI chr 3:97,640,923...97,667,617
Ensembl chr 3:97,640,579...97,664,066 		JBrowse link
G Ddc dopa decarboxylase decreases expression ISO belinostat results in decreased expression of DDC mRNA CTD PMID:27188386 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Ddx21 DExD-box helicase 21 decreases expression ISO belinostat results in decreased expression of DDX21 mRNA CTD PMID:19606018 NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238 		JBrowse link
G Defb1 defensin beta 1 decreases expression ISO belinostat results in decreased expression of DEFB1 mRNA CTD PMID:27188386 NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068 		JBrowse link
G Dennd1a DENN domain containing 1A decreases expression
multiple interactions 		ISO belinostat results in decreased expression of DENND1A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DENND1A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886 		JBrowse link
G Depdc7 DEP domain containing 7 increases expression
multiple interactions 		ISO belinostat results in increased expression of DEPDC7 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DEPDC7 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:111,554,701...111,575,979
Ensembl chr 3:111,554,706...111,575,979 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein increases expression
multiple interactions 		ISO belinostat results in increased expression of DEPTOR mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DEPTOR mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041 		JBrowse link
G Dgki diacylglycerol kinase, iota multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA CTD PMID:27188386 NCBI chr 4:66,377,897...66,839,790
Ensembl chr 4:66,387,126...66,990,832 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DHRS2 mRNA
belinostat results in increased expression of DHRS2 mRNA 		CTD PMID:19606018 PMID:27188386 NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588 		JBrowse link
G Diaph2 diaphanous-related formin 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of DIAPH2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DIAPH2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:96,700,535...97,528,080
Ensembl chr  X:96,700,726...97,528,080 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO belinostat results in decreased expression of DIO1 mRNA CTD PMID:27188386 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO belinostat results in increased expression of DKK1 mRNA CTD PMID:26272509 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO belinostat results in increased expression of DNAJB1 mRNA CTD PMID:19606018 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416 		JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression
multiple interactions 		ISO belinostat results in increased expression of DNER mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DNER mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:93,035,108...93,350,568 		JBrowse link
G Dock10 dedicator of cytokinesis 10 decreases expression ISO belinostat results in decreased expression of DOCK10 mRNA CTD PMID:27188386 NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973 		JBrowse link
G Dok5 docking protein 5 increases expression ISO belinostat results in increased expression of DOK5 mRNA CTD PMID:26272509 NCBI chr 3:179,934,419...180,071,334
Ensembl chr 3:179,934,552...180,071,333 		JBrowse link
G Dppa2 developmental pluripotency-associated 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of DPPA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DPPA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:66,008,002...66,020,044
Ensembl chr11:66,011,628...66,020,994 		JBrowse link
G Dppa5 developmental pluripotency associated 5 increases expression
multiple interactions 		ISO belinostat results in increased expression of DPPA5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DPPA5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:88,095,627...88,097,936
Ensembl chr 1:14,260,684...14,261,146 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L decreases expression ISO belinostat results in decreased expression of DTX3L mRNA CTD PMID:27188386 NCBI chr11:78,320,225...78,329,837
Ensembl chr11:78,317,650...78,329,837 		JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO belinostat results in increased expression of DUSP10 mRNA CTD PMID:26272509 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp9 dual specificity phosphatase 9 decreases expression ISO belinostat results in decreased expression of DUSP9 mRNA CTD PMID:27188386 NCBI chr  X:156,503,237...156,507,162
Ensembl chr  X:156,503,190...156,507,161 		JBrowse link
G Dynlt5 dynein light chain Tctex-type family member 5 increases expression ISO belinostat results in increased expression of DYNLT5 mRNA CTD PMID:27188386 NCBI chr 5:122,964,568...122,987,304
Ensembl chr 5:122,964,845...122,987,304 		JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO belinostat results in decreased expression of E2F2 mRNA CTD PMID:26272509 NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:153,682,789...153,706,087 		JBrowse link
G Eaf2 ELL associated factor 2 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EAF2 mRNA CTD PMID:27188386 NCBI chr11:77,465,585...77,509,993
Ensembl chr11:77,406,020...77,509,993 		JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression ISO belinostat results in decreased expression of ECHDC2 mRNA CTD PMID:27188386 NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610 		JBrowse link
G Edn1 endothelin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of EDN1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednra endothelin receptor type A increases expression
multiple interactions 		ISO belinostat results in increased expression of EDNRA mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA
belinostat results in increased expression of EDNRB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression ISO belinostat affects the expression of EEF1A1 mRNA CTD PMID:27015953 NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072 		JBrowse link
G Efcab2 EF-hand calcium binding domain 2 decreases expression ISO belinostat results in decreased expression of DRC8 mRNA CTD PMID:27188386 NCBI chr13:92,683,182...92,769,939
Ensembl chr13:92,684,086...92,782,558 		JBrowse link
G Efna1 ephrin A1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EFNA1 mRNA
belinostat results in increased expression of EFNA1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGF mRNA CTD PMID:27188386 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 decreases expression ISO belinostat results in decreased expression of EIF4G2 mRNA CTD PMID:19606018 NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:174,616,103...174,628,252 		JBrowse link
G Elmod1 ELMO domain containing 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of ELMOD1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ELMOD1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:63,194,539...63,251,526
Ensembl chr 8:63,137,295...63,251,322 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ELOVL2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ELOVL2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of EPB41L3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPB41L3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 increases expression ISO belinostat results in increased expression of EPB41L5 mRNA CTD PMID:26272509 NCBI chr13:33,221,705...33,321,400
Ensembl chr13:33,223,589...33,321,133 		JBrowse link
G Epcam epithelial cell adhesion molecule increases expression ISO belinostat results in increased expression of EPCAM mRNA CTD PMID:26272509 NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702 		JBrowse link
G Epdr1 ependymin related 1 decreases expression ISO belinostat results in decreased expression of EPDR1 mRNA CTD PMID:27188386 NCBI chr17:50,029,591...50,054,254
Ensembl chr17:50,029,256...50,054,250 		JBrowse link
G Epha1 Eph receptor A1 increases expression
multiple interactions 		ISO belinostat results in increased expression of EPHA1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHA1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474 		JBrowse link
G Epha3 Eph receptor A3 increases expression ISO belinostat results in increased expression of EPHA3 mRNA CTD PMID:26272509 NCBI chr11:14,585,041...14,920,721
Ensembl chr11:14,586,727...14,920,425 		JBrowse link
G Epha7 Eph receptor A7 increases expression ISO belinostat results in increased expression of EPHA7 mRNA CTD PMID:26272509 NCBI chr 5:47,771,776...47,925,189
Ensembl chr 5:47,771,865...47,925,058 		JBrowse link
G Ephb2 Eph receptor B2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of EPHB2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EPHB2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615 		JBrowse link
G Ermap erythroblast membrane associated protein (Scianna blood group) decreases expression ISO belinostat results in decreased expression of ERMAP mRNA CTD PMID:27188386 NCBI chr 5:138,074,155...138,088,340
Ensembl chr 5:138,065,824...138,087,015
Ensembl chr 5:138,065,824...138,087,015 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor increases expression
multiple interactions 		ISO belinostat results in increased expression of ETS1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ETS1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021 		JBrowse link
G Etv5 ETS variant transcription factor 5 decreases expression ISO belinostat results in decreased expression of ETV5 mRNA CTD PMID:27188386 NCBI chr11:92,113,171...92,170,758
Ensembl chr11:92,113,224...92,170,767 		JBrowse link
G Exo1 exonuclease 1 decreases expression ISO belinostat results in decreased expression of EXO1 protein CTD PMID:29733868 NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO belinostat results in increased expression of EZH1 mRNA CTD PMID:27188386 NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620 		JBrowse link
G F10 coagulation factor X decreases expression ISO belinostat results in decreased expression of F10 mRNA CTD PMID:27188386 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280 		JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO belinostat results in increased expression of F13A1 mRNA CTD PMID:27188386 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:28,020,845...28,197,948 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 decreases expression
increases expression
multiple interactions 		ISO belinostat results in decreased expression of F2RL1 mRNA
belinostat results in increased expression of F2RL1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F2RL1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO belinostat results in decreased expression of FABP1 mRNA CTD PMID:27188386 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113 		JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP3 mRNA CTD PMID:27188386 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Fam174b family with sequence similarity 174, member B decreases expression ISO belinostat results in decreased expression of FAM174B mRNA CTD PMID:27188386 NCBI chr 1:136,925,162...137,006,082
Ensembl chr 1:136,925,151...137,035,589 		JBrowse link
G Fam222a family with sequence similarity 222, member A decreases expression
multiple interactions 		ISO belinostat results in decreased expression of FAM222A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM222A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:47,647,221...47,693,703
Ensembl chr12:47,647,405...47,693,703 		JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression
multiple interactions 		ISO belinostat results in increased expression of FAM43A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM43A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297 		JBrowse link
G Fancg FA complementation group G decreases expression ISO belinostat results in decreased expression of FANCG mRNA CTD PMID:29733868 NCBI chr 5:62,027,494...62,037,202
Ensembl chr 5:62,027,500...62,035,787 		JBrowse link
G Far2 fatty acyl CoA reductase 2 decreases expression ISO belinostat results in decreased expression of FAR2 mRNA CTD PMID:27188386 NCBI chr 4:182,705,499...182,819,290
Ensembl chr 4:182,705,381...182,825,279 		JBrowse link
G Fbln1 fibulin 1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of FBLN1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBLN1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965 		JBrowse link
G Fbln2 fibulin 2 decreases expression ISO belinostat results in decreased expression of FBLN2 mRNA CTD PMID:27188386 NCBI chr 4:125,261,464...125,321,030
Ensembl chr 4:125,261,607...125,321,029 		JBrowse link
G Fbln7 fibulin 7 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBLN7 mRNA
belinostat results in decreased expression of FBLN7 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:136,564,825...136,601,205
Ensembl chr 3:136,564,917...136,601,198 		JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO belinostat results in decreased expression of FBN1 mRNA CTD PMID:27188386 NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283 		JBrowse link
G Fbxo43 F-box protein 43 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of FBXO43 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBXO43 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:69,218,298...69,231,873
Ensembl chr 7:69,218,299...69,230,310 		JBrowse link
G Fbxw4 F-box and WD repeat domain containing 4 decreases expression ISO belinostat results in decreased expression of FBXW4 mRNA CTD PMID:27188386 NCBI chr 1:254,375,921...254,465,173
Ensembl chr 1:254,375,923...254,463,277 		JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression
multiple interactions 		ISO belinostat results in increased expression of FGF4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085 		JBrowse link
G Fgf9 fibroblast growth factor 9 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FGF9 mRNA
belinostat results in decreased expression of FGF9 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:36,325,552...36,369,995
Ensembl chr15:36,325,599...36,367,926 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of FLT1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLT1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression ISO belinostat results in decreased expression of FMO5 mRNA CTD PMID:27188386 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464 		JBrowse link
G Folr1 folate receptor alpha decreases expression ISO belinostat results in decreased expression of FOLR1 mRNA CTD PMID:27188386 NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669 		JBrowse link
G Foxc2 forkhead box C2 increases expression ISO belinostat results in increased expression of FOXC2 mRNA CTD PMID:26272509 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:66,094,700...66,153,977 		JBrowse link
G Foxd3 forkhead box D3 increases expression
multiple interactions 		ISO belinostat results in increased expression of FOXD3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXD3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:119,450,532...119,452,898
Ensembl chr 5:119,450,394...119,452,786 		JBrowse link
G Foxh1 forkhead box H1 increases expression
multiple interactions 		ISO belinostat results in increased expression of FOXH1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXH1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:110,268,608...110,272,105
Ensembl chr 7:110,268,612...110,270,692 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXO1 mRNA
belinostat results in increased expression of FOXO1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Frem1 Fras1 related extracellular matrix 1 decreases expression ISO belinostat results in decreased expression of FREM1 mRNA CTD PMID:27188386 NCBI chr 5:102,367,201...102,515,464
Ensembl chr 5:102,367,201...102,515,404 		JBrowse link
G Frrs1l ferric-chelate reductase 1-like multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FRRS1L mRNA CTD PMID:27188386 NCBI chr 5:76,451,101...76,485,319
Ensembl chr 5:76,451,101...76,485,316 		JBrowse link
G Fut9 fucosyltransferase 9 increases expression ISO belinostat results in increased expression of FUT9 mRNA CTD PMID:27188386 NCBI chr 5:44,148,371...44,361,209
Ensembl chr 5:44,146,152...44,362,823 		JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO belinostat results in decreased expression of FZD5 mRNA CTD PMID:26272509 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:73,606,860...73,618,612 		JBrowse link
G Fzd7 frizzled class receptor 7 increases expression
multiple interactions 		ISO belinostat results in increased expression of FZD7 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FZD7 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:68,425,538...68,428,357
Ensembl chr 9:68,411,259...68,432,585 		JBrowse link
G G2 G2 protein decreases expression
multiple interactions 		ISO belinostat results in decreased expression of KIAA1549L mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KIAA1549L mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:110,961,478...111,237,308
Ensembl chr 3:110,961,478...111,237,223 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of GABRB3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:117,602,772...117,838,230
Ensembl chr 1:117,431,842...117,836,725 		JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of GAD1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO belinostat results in increased expression of GADD45A mRNA; belinostat results in increased expression of GADD45A protein CTD PMID:29733868 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 decreases expression ISO belinostat results in decreased expression of GALNT17 mRNA CTD PMID:27188386 NCBI chr12:30,959,460...31,418,150
Ensembl chr12:30,959,447...31,418,149 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GALNT3 mRNA
belinostat results in increased expression of GALNT3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323 		JBrowse link
G Gap43 growth associated protein 43 increases expression
multiple interactions 		ISO belinostat results in increased expression of GAP43 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAP43 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of GATA3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Gba3 glucosylceramidase beta 3 decreases expression ISO belinostat results in decreased expression of GBA3 mRNA CTD PMID:27188386 NCBI chr14:64,787,601...64,934,043
Ensembl chr14:64,787,601...64,934,043 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO belinostat results in decreased expression of GBE1 mRNA CTD PMID:27188386 NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638 		JBrowse link
G Gcat glycine C-acetyltransferase decreases expression ISO belinostat results in decreased expression of GCAT mRNA CTD PMID:27188386 NCBI chr 7:112,475,572...112,481,920
Ensembl chr 7:112,475,496...112,482,664 		JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDAP1L1 mRNA CTD PMID:27188386 NCBI chr 3:172,529,523...172,549,128
Ensembl chr 3:172,509,564...172,549,125 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GFRA1 mRNA
belinostat results in decreased expression of GFRA1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:267,325,297...267,557,037
Ensembl chr 1:267,326,817...267,556,501 		JBrowse link
G Glb1l3 galactosidase, beta 1-like 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of GLB1L3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GLB1L3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:33,454,914...33,496,641
Ensembl chr 8:33,454,914...33,496,641 		JBrowse link
G Gldn gliomedin increases expression ISO belinostat results in increased expression of GLDN mRNA CTD PMID:27188386 NCBI chr 8:63,575,270...63,619,346
Ensembl chr 8:63,575,270...63,619,346 		JBrowse link
G Glis3 GLIS family zinc finger 3 decreases expression ISO belinostat results in decreased expression of GLIS3 mRNA CTD PMID:26272509 NCBI chr 1:235,389,567...235,809,416
Ensembl chr 1:235,392,651...235,809,221 		JBrowse link
G Glt8d2 glycosyltransferase 8 domain containing 2 decreases expression ISO belinostat results in decreased expression of GLT8D2 mRNA CTD PMID:27188386 NCBI chr 7:22,917,055...22,968,616
Ensembl chr 7:22,917,100...22,968,930 		JBrowse link
G Gng11 G protein subunit gamma 11 increases expression ISO belinostat results in increased expression of GNG11 mRNA CTD PMID:26272509 NCBI chr 4:32,977,681...32,983,121
Ensembl chr 4:32,977,664...32,984,438 		JBrowse link
G Gpc6 glypican 6 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of GPC6 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:100,437,415...101,435,038
Ensembl chr15:100,437,943...101,435,027 		JBrowse link
G Gpr143 G protein-coupled receptor 143 decreases expression ISO belinostat results in decreased expression of GPR143 mRNA CTD PMID:27188386 NCBI chr  X:25,498,601...25,523,408
Ensembl chr  X:25,498,601...25,523,400 		JBrowse link
G Gpr27 G protein-coupled receptor 27 decreases expression ISO belinostat results in decreased expression of GPR27 mRNA CTD PMID:27188386 NCBI chr 4:133,884,894...133,886,027
Ensembl chr 4:133,883,234...133,904,093 		JBrowse link
G Gpx7 glutathione peroxidase 7 decreases expression ISO belinostat results in decreased expression of GPX7 mRNA CTD PMID:27188386 NCBI chr 5:128,373,881...128,381,866
Ensembl chr 5:128,372,875...128,381,725 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression
multiple interactions 		ISO belinostat results in increased expression of GREM1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GREM1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of GRHL3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GRHL3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:153,057,760...153,089,890
Ensembl chr 5:153,057,760...153,089,890 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression ISO belinostat results in increased expression of GRIA3 mRNA CTD PMID:27188386 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:125,103,782...125,369,679 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 increases expression ISO belinostat results in increased expression of GRIK1 mRNA CTD PMID:27188386 NCBI chr11:40,655,974...41,056,966
Ensembl chr11:40,655,975...41,056,517 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression ISO belinostat results in decreased expression of GRK6 mRNA CTD PMID:27188386 NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,182,160...9,197,954 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO belinostat results in increased phosphorylation of GSK3B protein CTD PMID:23671600 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G H1f0 H1.0 linker histone increases expression ISO belinostat results in increased expression of H1-0 mRNA CTD PMID:19606018 PMID:27188386 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006 		JBrowse link
G H1f10 H1.10 linker histone increases expression ISO belinostat results in increased expression of H1-10 mRNA CTD PMID:19606018 NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966 		JBrowse link
G H2ac6 H2A clustered histone 6 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2AC6 mRNA CTD PMID:27188386 NCBI chr17:47,403,701...47,404,167 JBrowse link
G H2bc12 H2B clustered histone 12 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2BC12 mRNA
belinostat results in decreased expression of H2BC12 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:47,181,477...47,181,940
Ensembl chr17:47,121,467...47,182,816 		JBrowse link
G H2bc14 H2B clustered histone 14 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of H2BC5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2BC5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:47,488,627...47,489,008 JBrowse link
G Hapln1 hyaluronan and proteoglycan link protein 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HAPLN1 mRNA
belinostat results in increased expression of HAPLN1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:22,366,967...22,431,709
Ensembl chr 2:22,366,967...22,429,098 		JBrowse link
G Hapln4 hyaluronan and proteoglycan link protein 4 decreases expression ISO belinostat results in decreased expression of HAPLN4 mRNA CTD PMID:27188386 NCBI chr16:19,367,041...19,375,173
Ensembl chr16:19,367,041...19,375,442 		JBrowse link
G Hbe1 hemoglobin subunit epsilon 1 decreases expression ISO belinostat results in decreased expression of HBE1 mRNA CTD PMID:27188386 NCBI chr 1:167,694,820...167,872,091
Ensembl chr 1:167,694,825...167,696,280 		JBrowse link
G Heg1 heart development protein with EGF-like domains 1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of HEG1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HEG1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:80,512,096...80,600,150
Ensembl chr11:80,512,096...80,600,092 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HES5 mRNA
belinostat results in decreased expression of HES5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021 		JBrowse link
G Hesx1 HESX homeobox 1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of HESX1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HESX1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr16:2,198,589...2,200,694
Ensembl chr16:2,198,589...2,200,694 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA
belinostat results in increased expression of HEY2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression ISO belinostat results in decreased expression of HGD mRNA CTD PMID:27188386 NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767 		JBrowse link
G Hhex hematopoietically expressed homeobox increases expression
multiple interactions 		ISO belinostat results in increased expression of HHEX mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HHEX mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604 		JBrowse link
G Hkdc1 hexokinase domain containing 1 decreases expression ISO belinostat results in decreased expression of HKDC1 mRNA CTD PMID:27188386 NCBI chr20:30,878,037...30,917,044
Ensembl chr20:30,878,319...30,916,704 		JBrowse link
G Hmx2 H6 family homeobox 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of HMX2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HMX2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:195,749,284...195,758,347
Ensembl chr 1:195,749,284...195,756,945 		JBrowse link
G Homer2 homer scaffold protein 2 decreases expression ISO belinostat results in decreased expression of HOMER2 mRNA CTD PMID:26272509 NCBI chr 1:144,968,207...145,069,022
Ensembl chr 1:144,976,436...145,068,997 		JBrowse link
G Hoxd3 homeo box D3 increases expression ISO belinostat results in increased expression of HOXD3 mRNA CTD PMID:27188386 NCBI chr 3:80,041,598...80,057,700
Ensembl chr 3:80,046,126...80,057,700 		JBrowse link
G Hoxd4 homeo box D4 increases expression ISO belinostat results in increased expression of HOXD4 mRNA CTD PMID:27188386 NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948 		JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like increases expression
multiple interactions 		ISO belinostat results in increased expression of HPDL mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPDL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:135,523,258...135,524,864
Ensembl chr 5:135,523,262...135,535,704 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO belinostat results in increased expression of HPGD mRNA CTD PMID:26272509 NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831 		JBrowse link
G Hpx hemopexin decreases expression ISO belinostat results in decreased expression of HPX mRNA CTD PMID:27188386 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Hunk hormonally upregulated Neu-associated kinase decreases expression ISO belinostat results in decreased expression of HUNK mRNA CTD PMID:27188386 NCBI chr11:43,127,244...43,244,502
Ensembl chr11:43,127,244...43,244,502 		JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO belinostat results in increased expression of HUS1 mRNA CTD PMID:29733868 NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134 		JBrowse link
G Hyi hydroxypyruvate isomerase decreases expression ISO belinostat results in decreased expression of HYI mRNA CTD PMID:27188386 NCBI chr 5:137,179,975...137,182,654
Ensembl chr 5:137,179,976...137,182,654 		JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 increases expression ISO belinostat results in increased expression of ICE2 mRNA CTD PMID:27188386 NCBI chr 8:78,921,962...78,965,983
Ensembl chr 8:78,924,421...78,966,200 		JBrowse link
G Id4 inhibitor of DNA binding 4 increases expression
multiple interactions 		ISO belinostat results in increased expression of ID4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ID4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression
multiple interactions 		ISO belinostat results in increased expression of IDH3A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IDH3A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223 		JBrowse link
G Idnk Idnk, gluconokinase decreases expression ISO belinostat results in decreased expression of IDNK mRNA CTD PMID:27188386 NCBI chr17:6,489,397...6,496,520
Ensembl chr17:6,488,982...6,499,822 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IDO1 mRNA CTD PMID:27188386 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:74,133,259...74,145,328 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO belinostat results in decreased expression of IFIT3 mRNA CTD PMID:27188386 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFITM1 mRNA CTD PMID:27188386 NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776 		JBrowse link
G Ifng interferon gamma multiple interactions ISO belinostat inhibits the reaction [IL15 protein results in increased expression of IFNG protein] CTD PMID:29301935 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO belinostat results in increased expression of IFNGR1 mRNA CTD PMID:19606018 NCBI chr 1:16,152,811...16,171,439
Ensembl chr 1:16,152,879...16,171,437 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO belinostat results in increased expression of IGF1 mRNA CTD PMID:23671600 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il15 interleukin 15 multiple interactions ISO belinostat inhibits the reaction [IL15 protein results in increased expression of IFNG protein] CTD PMID:29301935 NCBI chr19:42,536,160...42,611,349
Ensembl chr19:42,545,346...42,611,348 		JBrowse link
G Il17d interleukin 17D decreases expression ISO belinostat results in decreased expression of IL17D mRNA CTD PMID:27188386 NCBI chr15:35,786,898...35,804,391
Ensembl chr15:35,786,898...35,804,391 		JBrowse link
G Il17rb interleukin 17 receptor B decreases expression ISO belinostat results in decreased expression of IL17RB mRNA CTD PMID:27188386 NCBI chr16:5,186,961...5,200,657
Ensembl chr16:5,186,961...5,200,694 		JBrowse link
G Il17rd interleukin 17 receptor D decreases expression
multiple interactions 		ISO belinostat results in decreased expression of IL17RD mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of IL17RD mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta increases expression
multiple interactions 		ISO belinostat results in increased expression of IL20RB mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IL20RB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:109,854,012...109,889,363 		JBrowse link
G Il4r interleukin 4 receptor decreases expression ISO belinostat results in decreased expression of IL4R mRNA CTD PMID:27188386 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il6 interleukin 6 increases expression ISO belinostat results in increased expression of IL6 mRNA CTD PMID:23671600 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Impg1 interphotoreceptor matrix proteoglycan 1 increases expression ISO belinostat results in increased expression of IMPG1 mRNA CTD PMID:27188386 NCBI chr 8:90,123,821...90,269,903
Ensembl chr 8:90,123,821...90,269,903 		JBrowse link
G Incenp inner centromere protein decreases expression ISO belinostat results in decreased expression of INCENP mRNA CTD PMID:19606018 NCBI chr 1:215,945,558...216,017,247
Ensembl chr 1:215,948,283...215,977,084 		JBrowse link
G Inhba inhibin subunit beta A increases expression
multiple interactions 		ISO belinostat results in increased expression of INHBA mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of INHBA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase decreases expression ISO belinostat results in decreased expression of INPP1 mRNA CTD PMID:27188386 NCBI chr 9:56,161,816...56,209,774
Ensembl chr 9:56,161,852...56,234,569 		JBrowse link
G Irx1 iroquois homeobox 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of IRX1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IRX1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:33,123,122...33,128,951
Ensembl chr 1:33,123,122...33,128,951 		JBrowse link
G Irx2 iroquois homeobox 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of IRX2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IRX2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:32,489,512...32,494,930
Ensembl chr 1:32,489,512...32,494,930 		JBrowse link
G Itga2 integrin subunit alpha 2 increases expression ISO belinostat results in increased expression of ITGA2 mRNA CTD PMID:27188386 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itga3 integrin subunit alpha 3 decreases expression ISO belinostat results in decreased expression of ITGA3 mRNA CTD PMID:27188386 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901 		JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO belinostat results in decreased expression of ITGB5 mRNA CTD PMID:26272509 NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373 		JBrowse link
G Itih5 inter-alpha-trypsin inhibitor heavy chain 5 increases expression
multiple interactions 		ISO belinostat results in increased expression of ITIH5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITIH5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:73,161,886...73,261,930
Ensembl chr17:73,161,611...73,262,496 		JBrowse link
G Itm2a integral membrane protein 2A increases expression ISO belinostat results in increased expression of ITM2A mRNA CTD PMID:26272509 NCBI chr  X:76,559,183...76,565,144
Ensembl chr  X:76,559,181...76,565,437 		JBrowse link
G Itpripl2 ITPRIP like 2 decreases expression ISO belinostat results in decreased expression of ITPRIPL2 mRNA CTD PMID:27188386 NCBI chr 1:182,235,361...182,237,256
Ensembl chr 1:182,231,093...182,245,858 		JBrowse link
G Jazf1 JAZF zinc finger 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of JAZF1 mRNA CTD PMID:27188386 NCBI chr 4:83,210,054...83,513,790
Ensembl chr 4:83,210,058...83,513,644 		JBrowse link
G Kansl1l KAT8 regulatory NSL complex subunit 1-like decreases expression ISO belinostat results in decreased expression of KANSL1L mRNA CTD PMID:27188386 NCBI chr 9:75,660,865...75,766,730
Ensembl chr 9:75,661,233...75,766,745 		JBrowse link
G Kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of KCNJ13 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ13 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:95,509,228...95,528,400
Ensembl chr 9:95,510,877...95,520,817 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 decreases expression ISO belinostat results in decreased expression of KCNJ2 mRNA CTD PMID:27188386 NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA CTD PMID:27188386 NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104 		JBrowse link
G Kdm4c lysine demethylase 4C increases expression ISO belinostat results in increased expression of KDM4C mRNA CTD PMID:27188386 NCBI chr 5:93,146,404...93,353,040
Ensembl chr 5:93,146,969...93,353,040 		JBrowse link
G Kdr kinase insert domain receptor increases expression
multiple interactions 		ISO belinostat results in increased expression of KDR mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KDR mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO belinostat results in decreased expression of KEAP1 mRNA CTD PMID:19606018 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Kiaa0040 KIAA0040 ortholog increases expression
multiple interactions 		ISO belinostat results in increased expression of KIAA0040 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIAA0040 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:74,807,959...74,845,530
Ensembl chr13:74,807,982...74,845,530 		JBrowse link
G Klf5 KLF transcription factor 5 increases expression
multiple interactions 		ISO belinostat results in increased expression of KLF5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLF5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:82,472,081...82,487,267
Ensembl chr15:82,472,065...82,487,262 		JBrowse link
G Klf9 KLF transcription factor 9 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLF9 mRNA CTD PMID:27188386 NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641 		JBrowse link
G Klhl18 kelch-like family member 18 increases expression ISO belinostat results in increased expression of KLHL18 mRNA CTD PMID:27188386 NCBI chr 8:119,279,081...119,337,850
Ensembl chr 8:119,279,081...119,337,719 		JBrowse link
G Kpnb1 karyopherin subunit beta 1 decreases expression ISO belinostat results in decreased expression of KPNB1 mRNA CTD PMID:19606018 NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,642,082...82,670,856 		JBrowse link
G Krt18 keratin 18 increases expression
multiple interactions 		ISO belinostat results in increased expression of KRT18 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT18 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848 		JBrowse link
G Lactb lactamase, beta multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LACTB mRNA
belinostat results in increased expression of LACTB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:76,452,679...76,469,986
Ensembl chr 8:76,452,349...76,468,716 		JBrowse link
G Lama4 laminin subunit alpha 4 increases expression
multiple interactions 		ISO belinostat results in increased expression of LAMA4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMA4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr20:43,946,898...44,087,972
Ensembl chr20:43,946,898...44,087,972 		JBrowse link
G Lctl lactase-like decreases expression
multiple interactions 		ISO belinostat results in decreased expression of LCTL mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LCTL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:73,506,096...73,534,668
Ensembl chr 8:73,513,634...73,534,668 		JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 increases expression ISO belinostat results in increased expression of LGI1 mRNA CTD PMID:26272509 NCBI chr 1:245,455,691...245,497,036
Ensembl chr 1:245,455,599...245,499,095 		JBrowse link
G Lhx2 LIM homeobox 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of LHX2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LHX2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645 		JBrowse link
G Lhx8 LIM homeobox 8 increases expression
multiple interactions 		ISO belinostat results in increased expression of LHX8 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHX8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:245,904,712...245,929,376 		JBrowse link
G Lifr LIF receptor subunit alpha multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LIFR mRNA CTD PMID:27188386 NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364 		JBrowse link
G Limch1 LIM and calponin homology domains 1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of LIMCH1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LIMCH1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,466,433...41,778,837 		JBrowse link
G Lipg lipase G, endothelial type multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LIPG mRNA CTD PMID:27188386 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260 		JBrowse link
G Lman1 lectin, mannose-binding, 1 decreases expression ISO belinostat results in decreased expression of LMAN1 mRNA CTD PMID:26272509 NCBI chr18:61,778,971...61,800,960
Ensembl chr18:61,772,917...61,800,820 		JBrowse link
G Lmo2 LIM domain only 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of LMO2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LMO2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:110,809,912...110,833,075 		JBrowse link
G Lmo3 LIM domain only 3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of LMO3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LMO3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:172,965,944...173,028,980
Ensembl chr 4:172,965,951...173,025,156 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 decreases expression ISO belinostat results in decreased expression of LPAR1 mRNA CTD PMID:27188386 NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188 		JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 increases expression ISO belinostat results in increased expression of LPAR6 mRNA CTD PMID:26272509 NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783 		JBrowse link
G Lrrc10b leucine rich repeat containing 10B decreases expression ISO belinostat results in decreased expression of LRRC10B mRNA CTD PMID:27188386 NCBI chr 1:216,521,402...216,522,630
Ensembl chr 1:216,520,677...216,524,310 		JBrowse link
G Lrrc17 leucine rich repeat containing 17 increases expression ISO belinostat results in increased expression of LRRC17 mRNA CTD PMID:26272509 NCBI chr 4:14,393,632...14,424,048
Ensembl chr 4:14,393,640...14,424,048 		JBrowse link
G Lrrc55 leucine rich repeat containing 55 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LRRC55 mRNA
belinostat results in decreased expression of LRRC55 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:90,676,547...90,687,392
Ensembl chr 3:90,680,160...90,685,280 		JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of LRRN3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRRN3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:64,216,164...64,247,293
Ensembl chr 6:64,215,878...64,247,614 		JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of LRRTM1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRRTM1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:111,246,213...111,295,638
Ensembl chr 4:111,235,054...111,276,818 		JBrowse link
G Lyzl6 lysozyme-like 6 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LYZL6 mRNA
belinostat results in increased expression of LYZL6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:89,044,375...89,049,210
Ensembl chr10:89,044,375...89,049,210 		JBrowse link
G Macc1 MET transcriptional regulator MACC1 increases expression
multiple interactions 		ISO belinostat results in increased expression of MACC1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MACC1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:146,495,544...146,574,254
Ensembl chr 6:146,495,861...146,574,260 		JBrowse link
G Macroh2a1 macroH2A.1 histone multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MACROH2A1 mRNA
belinostat results in decreased expression of MACROH2A1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:8,484,340...8,547,268
Ensembl chr17:8,484,246...8,547,257 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of MAGI2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAGI2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:15,278,518...16,762,427
Ensembl chr 4:15,278,518...16,762,199 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO belinostat results in increased expression of MAP1LC3B mRNA CTD PMID:19606018 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO belinostat results in decreased expression of MAP3K5 mRNA CTD PMID:27188386 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO belinostat results in increased expression of MAP3K8 mRNA CTD PMID:27188386 NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452 		JBrowse link
G Map6 microtubule-associated protein 6 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of MAP6 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAP6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:162,980,339...163,046,548
Ensembl chr 1:162,980,181...163,046,548 		JBrowse link
G Map7d2 MAP7 domain containing 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of MAP7D2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAP7D2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:39,181,091...39,296,814
Ensembl chr  X:39,181,091...39,296,695 		JBrowse link
G Marveld1 MARVEL domain containing 1 decreases expression ISO belinostat results in decreased expression of MARVELD1 mRNA CTD PMID:27188386 NCBI chr 1:250,903,342...250,907,393
Ensembl chr 1:250,903,342...250,907,393 		JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of MBNL3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:135,526,256...135,621,499
Ensembl chr  X:135,532,494...135,621,976 		JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 decreases expression ISO belinostat results in decreased expression of MCHR1 mRNA CTD PMID:27188386 NCBI chr 7:114,641,721...114,644,913
Ensembl chr 7:114,641,580...114,644,919 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO belinostat results in decreased expression of MCM3 mRNA CTD PMID:19606018 NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:30,715,602...30,733,746 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO belinostat results in decreased expression of MCM7 mRNA CTD PMID:19606018 NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771 		JBrowse link
G Mcoln3 mucolipin TRP cation channel 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of MCOLN3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MCOLN3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:237,596,544...237,705,770
Ensembl chr 2:237,626,302...237,705,769 		JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of MEOX1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MEOX1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:87,318,668...87,338,169
Ensembl chr10:87,318,695...87,337,976 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase decreases expression
multiple interactions 		ISO belinostat results in decreased expression of MFNG mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:112,191,288...112,209,129
Ensembl chr 7:112,161,071...112,209,129 		JBrowse link
G Mgam maltase-glucoamylase decreases expression ISO belinostat results in decreased expression of MGAM mRNA CTD PMID:27188386 NCBI chr 4:70,408,263...70,568,752
Ensembl chr 4:70,408,263...70,568,752 		JBrowse link
G Miat myocardial infarction associated transcript decreases expression
multiple interactions 		ISO belinostat results in decreased expression of MIAT mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MIAT mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:50,075,026...50,090,259 JBrowse link
G Mlana melan-A decreases expression ISO belinostat results in decreased expression of MLANA mRNA CTD PMID:27188386 NCBI chr 1:236,883,075...236,897,693
Ensembl chr 1:236,883,075...236,896,880 		JBrowse link
G Mlh1 mutL homolog 1 multiple interactions ISO belinostat promotes the reaction [decitabine results in increased expression of MLH1 protein] CTD PMID:19259094 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Mpg N-methylpurine-DNA glycosylase increases expression ISO belinostat results in increased expression of MPG mRNA CTD PMID:29733868 NCBI chr10:15,900,697...15,906,981
Ensembl chr10:15,899,635...15,907,052 		JBrowse link
G Mpped2 metallophosphoesterase domain containing 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of MPPED2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MPPED2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:113,635,614...113,810,307
Ensembl chr 3:113,635,407...113,811,783 		JBrowse link
G Msx1 msh homeobox 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of MSX1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MSX1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:77,185,802...77,189,735
Ensembl chr14:77,185,802...77,189,735 		JBrowse link
G Msx2 msh homeobox 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MSX2 mRNA
belinostat results in increased expression of MSX2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:11,102,284...11,107,949
Ensembl chr17:11,102,247...11,107,945 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase decreases expression ISO belinostat results in decreased expression of MTHFS mRNA CTD PMID:27188386 NCBI chr 8:98,609,410...98,681,901
Ensembl chr 8:98,609,399...98,752,036 		JBrowse link
G Muc15 mucin 15, cell surface associated multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA
belinostat results in increased expression of MUC15 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:117,749,161...117,761,466
Ensembl chr 3:117,749,324...117,762,101 		JBrowse link
G Mylip myosin regulatory light chain interacting protein increases expression
multiple interactions 		ISO belinostat results in increased expression of MYLIP mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MYLIP mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:19,492,826...19,514,490
Ensembl chr17:19,492,826...19,514,471 		JBrowse link
G Mylk myosin light chain kinase decreases expression ISO belinostat results in decreased expression of MYLK mRNA CTD PMID:26272509 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Myo3b myosin IIIB increases expression ISO belinostat results in increased expression of MYO3B mRNA CTD PMID:26272509 NCBI chr 3:75,228,017...75,636,272
Ensembl chr 3:75,228,017...75,636,272 		JBrowse link
G Myof myoferlin increases expression ISO belinostat results in increased expression of MYOF mRNA CTD PMID:26272509 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768 		JBrowse link
G Nanog Nanog homeobox increases expression
multiple interactions 		ISO belinostat results in increased expression of NANOG mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NANOG mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression ISO belinostat results in decreased expression of NANOS1 mRNA CTD PMID:27188386 NCBI chr 1:269,883,713...269,887,611
Ensembl chr 1:269,883,536...269,895,417 		JBrowse link
G Nav3 neuron navigator 3 increases expression ISO belinostat results in increased expression of NAV3 mRNA CTD PMID:26272509 NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893 		JBrowse link
G Ncald neurocalcin delta decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NCALD mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NCALD mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482 		JBrowse link
G Ncan neurocan decreases expression ISO belinostat results in decreased expression of NCAN mRNA CTD PMID:26272509 NCBI chr16:19,335,907...19,362,371
Ensembl chr16:19,335,907...19,362,371 		JBrowse link
G Ndp norrin cystine knot growth factor NDP decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NDP mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NDP mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:8,379,569...8,404,019
Ensembl chr  X:8,379,569...8,406,802 		JBrowse link
G Nefl neurofilament light chain increases expression ISO belinostat results in increased expression of NEFL mRNA CTD PMID:26272509 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515 		JBrowse link
G Negr1 neuronal growth regulator 1 increases expression ISO belinostat results in increased expression of NEGR1 mRNA CTD PMID:27188386 NCBI chr 2:248,283,164...249,015,538
Ensembl chr 2:248,283,353...249,018,410 		JBrowse link
G Nell2 neural EGFL like 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NELL2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NELL2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:128,222,333...128,542,127
Ensembl chr 7:128,078,103...128,651,917 		JBrowse link
G Neto2 neuropilin and tolloid like 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NETO2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NETO2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:37,517,518...37,588,961
Ensembl chr19:37,517,587...37,591,413 		JBrowse link
G Nexmif neurite extension and migration factor multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NEXMIF mRNA CTD PMID:27188386 NCBI chr  X:73,153,786...73,284,943
Ensembl chr  X:73,153,786...73,178,639 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression 		ISO Bortezomib inhibits the reaction [belinostat results in increased expression of NFKB1 protein] CTD PMID:18223231 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions 		ISO belinostat results in increased expression of NFKBIA protein
Bortezomib inhibits the reaction [belinostat results in increased expression of NFKBIA protein] 		CTD PMID:18223231 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGEF mRNA CTD PMID:27188386 NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:95,594,823...95,692,251 		JBrowse link
G Nipal2 NIPA-like domain containing 2 decreases expression ISO belinostat results in decreased expression of NIPAL2 mRNA CTD PMID:27188386 NCBI chr 7:67,659,628...67,771,105
Ensembl chr 7:67,659,628...67,769,959 		JBrowse link
G Nlgn3 neuroligin 3 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NLGN3 mRNA
belinostat results in decreased expression of NLGN3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:70,469,251...70,497,380
Ensembl chr  X:70,469,457...70,497,379 		JBrowse link
G Nme8 NME/NM23 family member 8 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NME8 mRNA
belinostat results in increased expression of NME8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:49,932,861...50,000,610
Ensembl chr17:49,932,860...50,000,608 		JBrowse link
G Nmi N-myc (and STAT) interactor increases expression
multiple interactions 		ISO belinostat results in increased expression of NMI mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NMI mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:56,811,314...56,848,717 		JBrowse link
G Noct nocturnin multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NOCT mRNA CTD PMID:27188386 NCBI chr 2:137,422,074...137,442,282
Ensembl chr 2:137,422,074...137,442,282 		JBrowse link
G Nog noggin increases expression
multiple interactions 		ISO belinostat results in increased expression of NOG mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADAM12 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADGRG1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ADGRL3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ANKS1B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGEF37 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARNT2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of B3GNT5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of C14ORF39 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CALML4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCKBR mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CCND2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNKSR2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNTN3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of COLGALT2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CRYBA4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DAZL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DENND1A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DGKI mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGF mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ELOVL2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EOLA2-DT mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EPHB2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FAM222A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBLN1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBLN7 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FBXO43 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FGF9 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FRRS1L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GFRA1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPC6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GSEC mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2AC6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2BC12 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of H2BC5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HEG1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HES5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HESX1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HLA-DMB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of IL17RD mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ13 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KCNJ3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KIAA1549L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LCTL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LHX2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LIMCH1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LIPG mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LMO2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LMO3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of LRRC55 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MACROH2A1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAP6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAP7D2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MFNG mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MIAT mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MPPED2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NCALD mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NDP mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NELL2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NETO2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NEXMIF mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NIFK-AS1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NLGN3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NOL4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NRXN2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUCB2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OPLAH mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDE10A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PIEZO1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PLD5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PLXNC1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PNMA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRSS23 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB33A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB3IP mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAX mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RBFOX3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ROBO2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RPH3AL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RSL1D1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RTN1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of S1PR3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDSL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHC3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHISAL1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SIX3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC16A14 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC9B2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SMOC1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TNC mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TOX2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZEB1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ACSM3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADCYAP1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANO3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANXA2P2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARHGAP24 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ARRB1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATP8B1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BAG2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BAMBI mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BBS9 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BCL11A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BEX5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMP5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BMPER mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BNC2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BORCS8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BSPRY mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C11ORF96 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C19ORF33 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C8ORF34 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of C8ORF34-AS1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CASP8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC140 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC69 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCL26 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD9 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDH1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDH3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP126 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CEP85L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHGA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHODL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHRM3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CHRNA3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CIMAP3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNTN1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COBL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COMTD1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CPNE4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CR1L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRIP1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTHRC1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL12 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CXCL5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DACT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DCC mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DEPDC7 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DEPTOR mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DHRS2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DIAPH2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DNER mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DPPA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DPPA5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EAF2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDNRB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EFNA1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ELMOD1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPB41L3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHA1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ERVH48-1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ESRG mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ETS1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of F2RL1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FABP3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM162B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM43A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FGF4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FLT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXD3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXH1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXO1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FZD7 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRB3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAD1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GALNT3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GAP43 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GATA3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDAP1L1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GLB1L3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GREM1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GRHL3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HAPLN1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HEY2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HHEX mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HLA-DPB2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HMX2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of HPDL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ID4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IDH3A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IDO1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFI16 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IFITM1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IL20RB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of INHBA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IRX1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IRX2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ITIH5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of JAZF1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KDR mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KIAA0040 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLF5 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLF9 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KRT18 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LACTB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LAMA4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LHX8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LIFR mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LINC00491 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LINC00698 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LINC01003 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRRN3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRRTM1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LYZL6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MACC1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MAGI2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MBNL3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MCOLN3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MEOX1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MSX1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MSX2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MYLIP mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NANOG mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NEAT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NGEF mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NME8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NMI mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NOCT mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NPFFR2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NPY mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NQO1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NRP1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NWD2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAX3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAX7 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCDH10 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCDH11Y mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDGFA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDLIM1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDPN mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIPOX mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKDCC mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLA2G2A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLA2G4A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAAT3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAU mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PODXL mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POU2F3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POU5F1B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POU5F1P3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POU5F1P4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPARGC1B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPIC mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPM1K mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPP1R3B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRDM14 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKACA mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB3C mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RABGAP1L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RARRES2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RHOB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF144B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF217 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RTP1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX1T1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A10 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SAT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCG3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCGB3A2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCML1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCNN1A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEMA3E mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEPTIN6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINB9 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINI1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEZ6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFMBT2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGK3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC1A3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC35D3 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC38A4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC38A6 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLCO1B1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLCO4C1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SNAI2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SNAP25 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SOX8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SP140L mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of STMN2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1C2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACSTD2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAFA2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TC2N mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2A mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2C mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of THRB mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM30B mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM64 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFSF11 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNIK mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TPD52L1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRNP1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC29 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UGT3A1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UGT8 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of USP28 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UTF1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VASH2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VENTX mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VEPH1 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WFDC2 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WNT4 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA; [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZIC3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,625,875...74,628,103 		JBrowse link
G Nol4 nucleolar protein 4 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NOL4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NOL4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:14,207,303...14,569,697
Ensembl chr18:14,207,303...14,569,677 		JBrowse link
G Npffr2 neuropeptide FF receptor 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of NPFFR2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NPFFR2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr14:18,794,868...18,842,186
Ensembl chr14:18,797,234...18,842,186 		JBrowse link
G Npr3 natriuretic peptide receptor 3 increases expression ISO belinostat results in increased expression of NPR3 mRNA CTD PMID:26272509 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066 		JBrowse link
G Npy neuropeptide Y increases expression
multiple interactions 		ISO belinostat results in increased expression of NPY mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NPY mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NQO1 mRNA
belinostat results in increased expression of NQO1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nrp1 neuropilin 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of NRP1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NRP1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nrxn2 neurexin 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NRXN2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NRXN2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:213,155,673...213,271,526 		JBrowse link
G Nsun7 NOP2/Sun RNA methyltransferase family member 7 decreases expression ISO belinostat results in decreased expression of NSUN7 mRNA CTD PMID:27188386 NCBI chr14:42,233,062...42,289,013
Ensembl chr14:42,233,062...42,288,958 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO belinostat results in increased expression of NTRK3 mRNA CTD PMID:27188386 NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004 		JBrowse link
G Nucb2 nucleobindin 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of NUCB2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NUCB2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116 		JBrowse link
G Nudt12 nudix hydrolase 12 increases expression ISO belinostat results in increased expression of NUDT12 mRNA CTD PMID:27188386 NCBI chr 9:106,188,930...106,202,340
Ensembl chr 9:106,189,661...106,202,340 		JBrowse link
G Nwd2 NACHT and WD repeat domain containing 2 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NWD2 mRNA CTD PMID:27188386 NCBI chr14:44,833,623...45,024,962
Ensembl chr14:44,834,856...45,024,047 		JBrowse link
G Nxph2 neurexophilin 2 decreases expression ISO belinostat results in decreased expression of NXPH2 mRNA CTD PMID:26272509 NCBI chr 3:26,373,858...26,392,392
Ensembl chr 3:26,153,756...26,391,876 		JBrowse link
G Ociad2 OCIA domain containing 2 decreases expression ISO belinostat results in decreased expression of OCIAD2 mRNA CTD PMID:27188386 NCBI chr14:35,225,291...35,243,306
Ensembl chr14:35,225,255...35,243,311 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO belinostat results in increased expression of ODC1 mRNA CTD PMID:19606018 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO belinostat results in decreased expression of OGG1 mRNA; belinostat results in decreased expression of OGG1 protein CTD PMID:29733868 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Olfm3 olfactomedin 3 increases expression ISO belinostat results in increased expression of OLFM3 mRNA CTD PMID:26272509 NCBI chr 2:205,417,962...205,640,479
Ensembl chr 2:205,598,959...205,640,479 		JBrowse link
G Olfml3 olfactomedin-like 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of OLFML3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OLFML3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494 		JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of OPLAH mRNA CTD PMID:27188386 NCBI chr 7:109,892,136...109,932,403
Ensembl chr 7:109,891,405...109,915,979 		JBrowse link
G Pa2g4 proliferation-associated 2G4 decreases expression ISO belinostat results in decreased expression of PA2G4 mRNA CTD PMID:19606018 NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
increases expression
multiple interactions 		ISO belinostat results in increased cleavage of PARP1 protein
belinostat results in increased expression of PARP1 mRNA; belinostat results in increased expression of PARP1 protein
Bortezomib promotes the reaction [belinostat results in increased cleavage of PARP1 protein] 		CTD PMID:18223231 PMID:25537862 PMID:29733868 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression ISO belinostat results in decreased expression of PARP9 mRNA CTD PMID:27188386 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608 		JBrowse link
G Parvb parvin, beta decreases expression ISO belinostat results in decreased expression of PARVB mRNA CTD PMID:27188386 NCBI chr 7:117,240,238...117,325,744
Ensembl chr 7:117,240,029...117,325,748 		JBrowse link
G Pax3 paired box 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of PAX3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAX3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:87,015,960...87,112,531
Ensembl chr 9:87,016,999...87,124,141 		JBrowse link
G Pax7 paired box 7 increases expression
multiple interactions 		ISO belinostat results in increased expression of PAX7 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PAX7 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:157,279,623...157,381,188
Ensembl chr 5:157,279,623...157,381,121 		JBrowse link
G Pbx2 PBX homeobox 2 decreases expression ISO belinostat results in decreased expression of PBX2 mRNA CTD PMID:27188386 NCBI chr20:4,156,107...4,161,503
Ensembl chr20:4,156,107...4,161,827 		JBrowse link
G Pcdh10 protocadherin 10 increases expression
multiple interactions 		ISO belinostat results in increased expression of PCDH10 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PCDH10 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:130,553,432...130,619,591
Ensembl chr 2:130,553,425...130,613,407 		JBrowse link
G Pcdh7 protocadherin 7 decreases expression ISO belinostat results in decreased expression of PCDH7 mRNA CTD PMID:27188386 NCBI chr14:56,684,817...57,114,976
Ensembl chr14:56,687,725...57,112,665 		JBrowse link
G Pcdh8 protocadherin 8 increases expression ISO belinostat results in increased expression of PCDH8 mRNA CTD PMID:26272509 NCBI chr15:61,607,521...61,612,090
Ensembl chr15:61,607,521...61,612,097 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO belinostat results in decreased expression of PCSK9 mRNA CTD PMID:27188386 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pde10a phosphodiesterase 10A decreases expression
multiple interactions 		ISO belinostat results in decreased expression of PDE10A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PDE10A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:54,313,343...54,765,668
Ensembl chr 1:54,317,732...54,764,051 		JBrowse link
G Pde7b phosphodiesterase 7B increases expression ISO belinostat results in increased expression of PDE7B mRNA CTD PMID:27188386 NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions
increases expression
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDGFA mRNA
belinostat results in increased expression of PDGFA mRNA
belinostat results in decreased expression of PDGFA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDLIM1 mRNA
belinostat results in increased expression of PDLIM1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379 		JBrowse link
G Pdpn podoplanin increases expression
multiple interactions 		ISO belinostat results in increased expression of PDPN mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PDPN mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637 		JBrowse link
G Peg10 paternally expressed 10 increases expression ISO belinostat results in increased expression of PEG10 mRNA CTD PMID:19606018 NCBI chr 4:33,809,026...33,822,224
Ensembl chr 4:33,817,190...33,819,166
Ensembl chr 4:33,817,190...33,819,166 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 increases expression ISO belinostat results in increased expression of PEX13 mRNA CTD PMID:27188386 NCBI chr14:101,804,673...101,822,367
Ensembl chr14:101,804,673...101,822,367 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO belinostat results in increased expression of PHLDA1 mRNA CTD PMID:26272509 NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of PHLDA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PHLDA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:208,126,302...208,127,241
Ensembl chr 1:208,126,302...208,127,920 		JBrowse link
G Piezo1 piezo-type mechanosensitive ion channel component 1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PIEZO1 mRNA
belinostat results in decreased expression of PIEZO1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:67,453,120...67,515,347
Ensembl chr19:67,453,122...67,515,037 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO belinostat results in increased expression of PIM1 mRNA CTD PMID:26272509 NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764 		JBrowse link
G Pipox pipecolic acid and sarcosine oxidase increases expression
multiple interactions 		ISO belinostat results in increased expression of PIPOX mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIPOX mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:63,267,946...63,281,556
Ensembl chr10:63,267,972...63,282,273 		JBrowse link
G Pitx2 paired-like homeodomain 2 increases expression ISO belinostat results in increased expression of PITX2 mRNA CTD PMID:26272509 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:220,391,888...220,411,591 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic increases expression
multiple interactions 		ISO belinostat results in increased expression of PKDCC mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PKDCC mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042 		JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression
multiple interactions 		ISO belinostat results in increased expression of PLA2G2A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLA2G2A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression
multiple interactions 		ISO belinostat results in increased expression of PLA2G4A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLA2G4A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAAT3 mRNA CTD PMID:27188386 NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763 		JBrowse link
G Plau plasminogen activator, urokinase increases expression
multiple interactions 		ISO belinostat results in increased expression of PLAU mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PLAU mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plce1 phospholipase C, epsilon 1 decreases expression ISO belinostat results in decreased expression of PLCE1 mRNA CTD PMID:27188386 NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828 		JBrowse link
G Pld5 phospholipase D family, member 5 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of PLD5 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PLD5 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:90,426,689...90,765,072
Ensembl chr13:90,428,490...90,783,066 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO belinostat results in decreased expression of PLEKHA2 mRNA CTD PMID:27188386 NCBI chr16:73,641,338...73,704,068
Ensembl chr16:73,641,344...73,703,087 		JBrowse link
G Plg plasminogen decreases expression ISO belinostat results in decreased expression of PLG mRNA CTD PMID:27188386 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320 		JBrowse link
G Plpp5 phospholipid phosphatase 5 decreases expression ISO belinostat results in decreased expression of PLPP5 mRNA CTD PMID:27188386 NCBI chr16:73,052,204...73,056,609
Ensembl chr16:73,052,204...73,056,643 		JBrowse link
G Plxnc1 plexin C1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of PLXNC1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PLXNC1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:31,276,978...31,430,823
Ensembl chr 7:31,276,978...31,431,092 		JBrowse link
G Pnliprp2 pancreatic lipase related protein 2 decreases expression ISO belinostat results in decreased expression of PNLIPRP2 mRNA CTD PMID:27188386 NCBI chr 1:267,883,906...267,902,572
Ensembl chr 1:267,883,906...267,902,572 		JBrowse link
G Pnma2 PNMA family member 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of PNMA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PNMA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:45,287,445...45,296,340
Ensembl chr15:45,286,304...45,298,080 		JBrowse link
G Podxl podocalyxin-like increases expression
multiple interactions 		ISO belinostat results in increased expression of PODXL mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PODXL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:61,102,434...61,149,131
Ensembl chr 4:61,102,419...61,149,789 		JBrowse link
G Polr3g RNA polymerase III subunit G increases expression
multiple interactions 		ISO belinostat results in increased expression of POLR3G mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POLR3G mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:13,680,893...13,721,802
Ensembl chr 2:13,680,895...13,721,802 		JBrowse link
G Pou2f3 POU class 2 homeobox 3 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of POU2F3 mRNA
belinostat results in increased expression of POU2F3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:52,392,363...52,474,756
Ensembl chr 8:52,392,497...52,474,756 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO belinostat results in increased expression of POU5F1 mRNA CTD PMID:26272509 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598 		JBrowse link
G Pou6f2 POU class 6 homeobox 2 increases expression ISO belinostat results in increased expression of POU6F2 mRNA CTD PMID:27188386 NCBI chr17:51,040,522...51,616,716
Ensembl chr17:51,167,771...51,616,597 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression
multiple interactions 		ISO belinostat results in increased expression of PPARGC1B mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPARGC1B mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466 		JBrowse link
G Ppic peptidylprolyl isomerase C increases expression
multiple interactions 		ISO belinostat results in increased expression of PPIC mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPIC mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:49,040,690...49,053,296
Ensembl chr18:49,040,692...49,053,466 		JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression
multiple interactions 		ISO belinostat results in increased expression of PPM1K mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPM1K mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:88,942,226...88,969,139
Ensembl chr 4:88,942,386...88,969,136 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO belinostat results in increased expression of PPP1R15A mRNA CTD PMID:29733868 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B increases expression
multiple interactions 		ISO belinostat results in increased expression of PPP1R3B mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PPP1R3B mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr16:63,533,318...63,545,683
Ensembl chr16:63,532,842...63,549,997 		JBrowse link
G Ppp4r4 protein phosphatase 4, regulatory subunit 4 increases expression ISO belinostat results in increased expression of PPP4R4 mRNA CTD PMID:27188386 NCBI chr 6:128,427,884...128,518,776
Ensembl chr 6:128,427,893...128,528,039 		JBrowse link
G Prdm14 PR/SET domain 14 increases expression
multiple interactions 		ISO belinostat results in increased expression of PRDM14 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRDM14 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:10,864,137...10,876,666
Ensembl chr 5:10,864,137...10,876,666 		JBrowse link
G Prima1 proline rich membrane anchor 1 decreases expression ISO belinostat results in decreased expression of PRIMA1 mRNA CTD PMID:27188386 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:128,103,175...128,154,865 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression
multiple interactions 		ISO belinostat results in increased expression of PRKACA mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRKACA mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prr15 proline rich 15 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PRR15 mRNA CTD PMID:27188386 NCBI chr 4:84,762,357...84,765,403
Ensembl chr 4:84,761,523...84,768,442 		JBrowse link
G Prss23 serine protease 23 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of PRSS23 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PRSS23 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871 		JBrowse link
G Pstk phosphoseryl-tRNA kinase decreases expression ISO belinostat results in decreased expression of PSTK mRNA CTD PMID:27188386 NCBI chr 1:195,587,911...195,598,326
Ensembl chr 1:195,587,890...195,604,035 		JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4A3 decreases expression ISO belinostat results in decreased expression of PTP4A3 mRNA CTD PMID:27188386 NCBI chr 7:107,518,220...107,549,949
Ensembl chr 7:107,541,047...107,549,949 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 decreases expression ISO belinostat results in decreased expression of PTPN3 mRNA CTD PMID:27188386 NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:76,703,687...76,860,470 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 decreases expression ISO belinostat results in decreased expression of PTPN5 mRNA CTD PMID:27188386 NCBI chr 1:106,756,896...106,817,369
Ensembl chr 1:106,756,896...106,816,828 		JBrowse link
G Ptx3 pentraxin 3 decreases expression ISO belinostat results in decreased expression of PTX3 mRNA CTD PMID:26272509 NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372 		JBrowse link
G Pyroxd2 pyridine nucleotide-disulphide oxidoreductase domain 2 decreases expression ISO belinostat results in decreased expression of PYROXD2 mRNA CTD PMID:27188386 NCBI chr 1:251,472,609...251,498,316
Ensembl chr 1:251,471,849...251,498,008 		JBrowse link
G Rab29 RAB29, member RAS oncogene family increases expression ISO belinostat results in increased expression of RAB29 mRNA CTD PMID:27188386 NCBI chr13:45,859,930...45,865,468
Ensembl chr13:45,859,961...45,865,610 		JBrowse link
G Rab33a RAB33A, member RAS oncogene family multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB33A mRNA CTD PMID:27188386 NCBI chr  X:132,572,133...132,584,255
Ensembl chr  X:132,572,148...132,584,254 		JBrowse link
G Rab3c RAB3C, member RAS oncogene family increases expression
multiple interactions 		ISO belinostat results in increased expression of RAB3C mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RAB3C mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:43,353,822...43,577,226
Ensembl chr 2:43,361,093...43,577,022 		JBrowse link
G Rab3ip RAB3A interacting protein multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAB3IP mRNA CTD PMID:27188386 NCBI chr 7:54,417,418...54,461,253
Ensembl chr 7:54,418,358...54,447,000 		JBrowse link
G Rabgap1l RAB GTPase activating protein 1-like increases expression
multiple interactions 		ISO belinostat results in increased expression of RABGAP1L mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RABGAP1L mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:74,997,542...75,593,240
Ensembl chr13:74,997,542...75,533,816 		JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO belinostat results in decreased expression of RAC1 mRNA CTD PMID:19606018 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component decreases expression ISO belinostat results in decreased expression of RAD17 mRNA CTD PMID:29733868 NCBI chr 2:33,498,335...33,528,614
Ensembl chr 2:33,498,336...33,528,144 		JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase decreases expression ISO belinostat results in decreased expression of RAD18 mRNA CTD PMID:29733868 NCBI chr 4:147,291,463...147,376,904
Ensembl chr 4:147,291,276...147,376,869 		JBrowse link
G Rad51c RAD51 paralog C decreases expression ISO belinostat results in decreased expression of RAD51C mRNA; belinostat results in decreased expression of RAD51C protein CTD PMID:29733868 NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,702,299...72,729,143 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO belinostat results in decreased expression of RAD9A mRNA CTD PMID:29733868 NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161 		JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO belinostat results in decreased expression of RAN mRNA CTD PMID:19606018 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 decreases expression ISO belinostat results in decreased expression of RARRES1 mRNA CTD PMID:27188386 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of RARRES2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RARRES2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457 		JBrowse link
G Rasef RAS and EF hand domain containing increases expression ISO belinostat results in increased expression of RASEF mRNA CTD PMID:26272509 NCBI chr 5:92,595,148...92,665,526
Ensembl chr 5:92,595,148...92,666,117 		JBrowse link
G Rax retina and anterior neural fold homeobox decreases expression
multiple interactions 		ISO belinostat results in decreased expression of RAX mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RAX mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:61,733,322...61,737,444
Ensembl chr18:61,733,322...61,737,444 		JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of RBFOX3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RBFOX3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:104,218,940...104,655,863
Ensembl chr10:104,218,940...104,551,945 		JBrowse link
G Rcbtb2 RCC1 and BTB domain containing protein 2 decreases expression ISO belinostat results in decreased expression of RCBTB2 mRNA CTD PMID:27188386 NCBI chr15:54,729,367...54,774,004
Ensembl chr15:54,729,332...54,793,313 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 decreases expression ISO belinostat results in decreased expression of RCC2 mRNA CTD PMID:19606018 NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:158,277,476...158,300,294 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases acetylation 		ISO Bortezomib inhibits the reaction [belinostat results in increased acetylation of RELA protein] CTD PMID:18223231 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Reln reelin increases expression ISO belinostat results in increased expression of RELN mRNA CTD PMID:26272509 NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162 		JBrowse link
G Rev1 REV1, DNA directed polymerase decreases expression ISO belinostat results in decreased expression of REV1 mRNA CTD PMID:29733868 NCBI chr 9:47,773,907...47,847,554
Ensembl chr 9:47,773,907...47,847,332 		JBrowse link
G Rhob ras homolog family member B increases expression
multiple interactions 		ISO belinostat results in increased expression of RHOB mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RHOB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rnf144b ring finger protein 144B increases expression
multiple interactions 		ISO belinostat results in increased expression of RNF144B mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF144B mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:17,637,564...17,786,685
Ensembl chr17:17,639,079...17,769,037 		JBrowse link
G Rnf150 ring finger protein 150 increases expression
multiple interactions 		ISO belinostat results in increased expression of RNF150 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF150 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:41,912,276...42,133,217
Ensembl chr19:41,912,276...42,133,217 		JBrowse link
G Rnf180 ring finger protein 180 decreases expression ISO belinostat results in decreased expression of RNF180 mRNA CTD PMID:27188386 NCBI chr 2:38,064,026...38,244,854
Ensembl chr 2:38,064,031...38,265,358 		JBrowse link
G Rnf217 ring finger protein 217 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RNF217 mRNA
belinostat results in increased expression of RNF217 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:27,835,741...27,927,805
Ensembl chr 1:27,835,148...27,928,044 		JBrowse link
G Robo2 roundabout guidance receptor 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of ROBO2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ROBO2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:26,015,919...27,583,750
Ensembl chr11:26,015,919...26,876,185 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RPH3AL mRNA CTD PMID:27188386 NCBI chr10:61,188,288...61,331,591
Ensembl chr10:61,188,293...61,300,145 		JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RSL1D1 mRNA CTD PMID:27188386 NCBI chr10:4,931,839...4,943,726
Ensembl chr10:4,904,792...4,946,566 		JBrowse link
G RT1-DMb RT1 class II, locus DMb decreases expression
multiple interactions 		ISO belinostat results in decreased expression of HLA-DMB mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of HLA-DMB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246 		JBrowse link
G RT1-Ha RT1 class II, locus Ha decreases expression ISO belinostat results in decreased expression of HLA-DPA1 mRNA CTD PMID:27188386 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G Rtn1 reticulon 1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RTN1 mRNA
belinostat results in decreased expression of RTN1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:96,499,137...96,719,340
Ensembl chr 6:96,499,134...96,719,340 		JBrowse link
G Rtp1 receptor (chemosensory) transporter protein 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RTP1 mRNA CTD PMID:27188386 NCBI chr11:90,927,633...90,930,149
Ensembl chr11:90,927,633...90,930,149 		JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of RUNX1T1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of RUNX1T1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:31,984,946...32,136,878
Ensembl chr 5:31,984,855...32,132,855 		JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression
multiple interactions 		ISO belinostat results in increased expression of S100A10 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of S100A10 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of S1PR3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of S1PR3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SAT1 mRNA
belinostat results in increased expression of SAT1 mRNA 		CTD PMID:19606018 PMID:26272509 PMID:27188386 NCBI chr  X:44,008,089...44,011,376
Ensembl chr  X:44,006,781...44,011,374 		JBrowse link
G Scg3 secretogranin III increases expression
multiple interactions 		ISO belinostat results in increased expression of SCG3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCG3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:85,280,253...85,322,484
Ensembl chr 8:85,280,253...85,361,874 		JBrowse link
G Scgb3a2 secretoglobin, family 3A, member 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCGB3A2 mRNA
belinostat results in increased expression of SCGB3A2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr18:36,183,745...36,186,667
Ensembl chr18:36,183,698...36,186,742 		JBrowse link
G Sclt1 sodium channel and clathrin linker 1 increases expression ISO belinostat results in increased expression of SCLT1 mRNA CTD PMID:27188386 NCBI chr 2:126,533,436...126,691,879
Ensembl chr 2:126,533,560...126,691,971 		JBrowse link
G Scml1 Scm polycomb group protein like 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCML1 mRNA
belinostat results in increased expression of SCML1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:36,526,068...36,543,336
Ensembl chr  X:36,526,068...36,544,450 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha increases expression
multiple interactions 		ISO belinostat results in increased expression of SCNN1A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SCNN1A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405 		JBrowse link
G Sdsl serine dehydratase-like decreases expression
multiple interactions 		ISO belinostat results in decreased expression of SDSL mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDSL mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr12:41,760,252...41,770,465
Ensembl chr12:41,760,252...41,770,465 		JBrowse link
G Sema3b semaphorin 3B decreases expression ISO belinostat results in decreased expression of SEMA3B mRNA CTD PMID:27188386 NCBI chr 8:117,150,307...117,161,570
Ensembl chr 8:117,150,589...117,157,658 		JBrowse link
G Sema3c semaphorin 3C increases expression ISO belinostat results in increased expression of SEMA3C mRNA CTD PMID:26272509 NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:18,538,454...18,701,740 		JBrowse link
G Sema3e semaphorin 3E increases expression
multiple interactions 		ISO belinostat results in increased expression of SEMA3E mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEMA3E mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:21,252,686...21,510,449
Ensembl chr 4:21,210,734...21,510,374 		JBrowse link
G Sema3f semaphorin 3F decreases expression ISO belinostat results in decreased expression of SEMA3F mRNA CTD PMID:27188386 NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206 		JBrowse link
G Sema6d semaphorin 6D decreases expression ISO belinostat results in decreased expression of SEMA6D mRNA CTD PMID:26272509 NCBI chr 3:131,801,680...132,394,578
Ensembl chr 3:132,337,343...132,394,584 		JBrowse link
G Septin6 septin 6 increases expression
multiple interactions 		ISO belinostat results in increased expression of SEPTIN6 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEPTIN6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:121,018,951...121,157,677
Ensembl chr  X:121,018,944...121,095,792 		JBrowse link
G Serpina1 serpin family A member 1 decreases expression ISO belinostat results in decreased expression of SERPINA1 mRNA CTD PMID:27188386 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Serpina7 serpin family A member 7 decreases expression ISO belinostat results in decreased expression of SERPINA7 mRNA CTD PMID:27188386 NCBI chr  X:107,452,044...107,510,958
Ensembl chr  X:107,452,044...107,457,681 		JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO belinostat results in decreased expression of SERPINB1 mRNA CTD PMID:27188386 NCBI chr17:31,799,446...31,807,853
Ensembl chr17:31,799,415...31,808,166 		JBrowse link
G Serpinb9 serpin family B member 9 increases expression
multiple interactions 		ISO belinostat results in increased expression of SERPINB9 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINB9 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974 		JBrowse link
G Serpini1 serpin family I member 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of SERPINI1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINI1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:162,645,209...162,731,737
Ensembl chr 2:162,645,350...162,731,740 		JBrowse link
G Sesn3 sestrin 3 increases expression ISO belinostat results in increased expression of SESN3 mRNA CTD PMID:26272509 NCBI chr 8:19,415,307...19,470,943
Ensembl chr 8:19,415,347...19,466,904 		JBrowse link
G Sez6 seizure related 6 homolog increases expression
multiple interactions 		ISO belinostat results in increased expression of SEZ6 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SEZ6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:63,317,065...63,366,733
Ensembl chr10:63,316,953...63,366,723 		JBrowse link
G Sfmbt2 Scm-like with four mbt domains 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of SFMBT2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SFMBT2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:72,844,037...73,038,599
Ensembl chr17:72,845,708...73,032,172 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of SGK3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SGK3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:14,126,257...14,198,331 		JBrowse link
G Shc3 SHC adaptor protein 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHC3 mRNA CTD PMID:27188386 NCBI chr17:13,803,980...13,924,433
Ensembl chr17:13,803,781...13,924,433 		JBrowse link
G Shisal1 shisa like 1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SHISAL1 mRNA
belinostat results in decreased expression of SHISAL1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:117,388,210...117,491,539 JBrowse link
G Shroom1 shroom family member 1 decreases expression ISO belinostat results in decreased expression of SHROOM1 mRNA CTD PMID:27188386 NCBI chr10:38,121,971...38,134,832
Ensembl chr10:38,122,500...38,132,435 		JBrowse link
G Siae sialic acid acetylesterase increases expression ISO belinostat results in increased expression of SIAE mRNA CTD PMID:27188386 NCBI chr 8:45,507,465...45,542,740
Ensembl chr 8:45,507,326...45,542,740 		JBrowse link
G Six3 SIX homeobox 3 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of SIX3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SIX3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:14,791,937...14,796,365
Ensembl chr 6:14,789,354...14,804,175 		JBrowse link
G Six6os1 Six6 opposite strand transcript 1 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of C14ORF39 mRNA
belinostat results in decreased expression of C14ORF39 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:97,314,829...97,351,069
Ensembl chr 6:97,314,712...97,351,171 		JBrowse link
G Skap2 src kinase associated phosphoprotein 2 increases expression ISO belinostat results in increased expression of SKAP2 mRNA CTD PMID:27188386 NCBI chr 4:82,281,221...82,431,664
Ensembl chr 4:82,263,709...82,432,886 		JBrowse link
G Slc16a14 solute carrier family 16, member 14 multiple interactions
decreases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC16A14 mRNA
belinostat results in decreased expression of SLC16A14 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:93,558,144...93,585,396
Ensembl chr 9:93,558,144...93,585,396 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC1A3 mRNA CTD PMID:27188386 NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:59,482,709...59,557,808 		JBrowse link
G Slc25a21 solute carrier family 25 member 21 decreases expression ISO belinostat results in decreased expression of SLC25A21 mRNA CTD PMID:27188386 NCBI chr 6:79,938,480...80,437,937
Ensembl chr 6:79,938,480...80,437,502 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA CTD PMID:27188386 NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581 		JBrowse link
G Slc35d3 solute carrier family 35, member D3 increases expression
multiple interactions 		ISO belinostat results in increased expression of SLC35D3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC35D3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:16,389,308...16,392,780
Ensembl chr 1:16,389,308...16,392,780 		JBrowse link
G Slc35f3 solute carrier family 35, member F3 decreases expression ISO belinostat results in decreased expression of SLC35F3 mRNA CTD PMID:27188386 NCBI chr19:71,000,144...71,270,829
Ensembl chr19:71,000,265...71,269,517 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 increases expression
multiple interactions 		ISO belinostat results in increased expression of SLC38A4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC38A4 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:130,023,980...130,082,097 		JBrowse link
G Slc38a6 solute carrier family 38, member 6 increases expression
multiple interactions 		ISO belinostat results in increased expression of SLC38A6 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC38A6 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:97,723,526...97,814,394
Ensembl chr 6:97,723,471...97,785,791 		JBrowse link
G Slc43a1 solute carrier family 43 member 1 increases expression ISO belinostat results in increased expression of SLC43A1 mRNA CTD PMID:26272509 NCBI chr 3:90,327,250...90,353,438
Ensembl chr 3:90,327,149...90,353,438 		JBrowse link
G Slc44a3 solute carrier family 44, member 3 decreases expression ISO belinostat results in decreased expression of SLC44A3 mRNA CTD PMID:27188386 NCBI chr 2:212,234,425...212,312,886
Ensembl chr 2:212,236,853...212,312,982 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 increases expression ISO belinostat results in increased expression of SLC6A2 mRNA CTD PMID:27188386 NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO belinostat results in decreased expression of SLC7A11 mRNA CTD PMID:27188386 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Slc9b2 solute carrier family 9 member B2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of SLC9B2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC9B2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:226,400,358...226,435,039
Ensembl chr 2:226,410,263...226,435,030 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression
multiple interactions 		ISO belinostat results in increased expression of SLCO4C1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLCO4C1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:104,624,802...104,676,462
Ensembl chr 9:104,624,802...104,676,462 		JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO belinostat results in increased expression of SLFN12 mRNA CTD PMID:27188386 NCBI chr10:68,492,135...68,515,674
Ensembl chr10:68,508,916...68,513,991 		JBrowse link
G Slit1 slit guidance ligand 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of SLIT1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLIT1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:250,358,917...250,507,476
Ensembl chr 1:250,358,919...250,507,476 		JBrowse link
G Slit2 slit guidance ligand 2 increases expression ISO belinostat results in increased expression of SLIT2 mRNA CTD PMID:26272509 NCBI chr14:66,829,661...67,168,517
Ensembl chr14:66,829,661...67,167,146 		JBrowse link
G Smarca2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of SMARCA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMARCA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:233,617,277...233,784,908
Ensembl chr 1:233,617,366...233,784,869 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of SMOC1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SMOC1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956 		JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of SNAI2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SNAI2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349 		JBrowse link
G Snap25 synaptosome associated protein 25 increases expression
multiple interactions 		ISO belinostat results in increased expression of SNAP25 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SNAP25 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:144,494,595...144,576,448 		JBrowse link
G Snx10 sorting nexin 10 decreases expression ISO belinostat results in decreased expression of SNX10 mRNA CTD PMID:27188386 NCBI chr 4:81,943,262...82,007,667
Ensembl chr 4:81,943,287...82,007,651 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 decreases expression ISO belinostat results in decreased expression of SOCS3 mRNA CTD PMID:26272509 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Sox6 SRY-box transcription factor 6 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SOX6 mRNA CTD PMID:27188386 NCBI chr 1:179,157,678...179,769,243
Ensembl chr 1:179,163,566...179,711,727 		JBrowse link
G Sox8 SRY-box transcription factor 8 increases expression
multiple interactions 		ISO belinostat results in increased expression of SOX8 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SOX8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr10:15,089,357...15,094,345
Ensembl chr10:15,089,357...15,094,345 		JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 increases expression ISO belinostat results in increased expression of SPINK2 mRNA CTD PMID:26272509 NCBI chr14:31,321,976...31,328,622
Ensembl chr14:31,322,010...31,328,622 		JBrowse link
G Spx spexin hormone decreases expression ISO belinostat results in decreased expression of SPX mRNA CTD PMID:27188386 NCBI chr 4:177,087,053...177,093,091
Ensembl chr 4:177,087,256...177,093,091 		JBrowse link
G Sspn sarcospan decreases expression ISO belinostat results in decreased expression of SSPN mRNA CTD PMID:27188386 NCBI chr 4:180,620,762...180,666,893
Ensembl chr 4:180,627,848...180,662,284 		JBrowse link
G Sst somatostatin increases expression ISO belinostat results in increased expression of SST mRNA CTD PMID:26272509 NCBI chr11:90,461,546...90,462,823
Ensembl chr11:90,461,546...90,462,823 		JBrowse link
G Stc2 stanniocalcin 2 decreases expression ISO belinostat results in decreased expression of STC2 mRNA CTD PMID:27188386 NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447 		JBrowse link
G Stk32a serine/threonine kinase 32A decreases expression ISO belinostat results in decreased expression of STK32A mRNA CTD PMID:27188386 NCBI chr18:35,509,791...35,620,421
Ensembl chr18:35,509,982...35,628,985 		JBrowse link
G Stmn2 stathmin 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of STMN2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of STMN2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A increases expression
decreases expression
multiple interactions 		ISO belinostat results in increased expression of SULT1C2 mRNA
belinostat results in decreased expression of SULT1C2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SULT1C2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO belinostat results in decreased expression of SULT2A1 mRNA CTD PMID:27188386 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Susd1 sushi domain containing 1 decreases expression ISO belinostat results in decreased expression of SUSD1 mRNA CTD PMID:27188386 NCBI chr 5:78,952,781...79,076,121
Ensembl chr 5:78,952,781...79,070,781 		JBrowse link
G Synj2 synaptojanin 2 decreases expression ISO belinostat results in decreased expression of SYNJ2 mRNA CTD PMID:26272509 NCBI chr 1:48,923,742...49,027,153
Ensembl chr 1:48,923,737...49,038,650 		JBrowse link
G Synm synemin decreases expression ISO belinostat results in decreased expression of SYNM mRNA CTD PMID:27188386 NCBI chr 1:130,743,891...130,774,254
Ensembl chr 1:130,743,897...130,773,824 		JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 increases expression ISO belinostat results in increased expression of TACC1 mRNA CTD PMID:19606018 NCBI chr16:73,515,016...73,598,395
Ensembl chr16:73,514,889...73,598,394 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TACSTD2 mRNA
belinostat results in increased expression of TACSTD2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:98,033,251...98,039,323 		JBrowse link
G Tafa2 TAFA chemokine like family member 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of TAFA2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAFA2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 7:60,827,985...61,303,873
Ensembl chr 7:60,891,958...61,303,869 		JBrowse link
G Taok3 TAO kinase 3 increases expression ISO belinostat results in increased expression of TAOK3 mRNA CTD PMID:26272509 NCBI chr12:44,973,180...45,134,439
Ensembl chr12:44,973,180...45,134,439 		JBrowse link
G Tc2n tandem C2 domains, nuclear increases expression
multiple interactions 		ISO belinostat results in increased expression of TC2N mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TC2N mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:126,526,006...126,622,163
Ensembl chr 6:126,526,009...126,614,215 		JBrowse link
G Tcaim T cell activation inhibitor, mitochondrial decreases expression ISO belinostat results in decreased expression of TCAIM mRNA CTD PMID:27188386 NCBI chr 8:131,292,275...131,323,557
Ensembl chr 8:131,292,351...131,323,571 		JBrowse link
G Tfap2a transcription factor AP-2 alpha increases expression
multiple interactions 		ISO belinostat results in increased expression of TFAP2A mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2A mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Tfap2b transcription factor AP-2 beta increases expression
multiple interactions 		ISO belinostat results in increased expression of TFAP2B mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2B mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 9:29,282,703...29,312,568
Ensembl chr 9:29,282,825...29,312,568 		JBrowse link
G Tfap2c transcription factor AP-2 gamma increases expression
multiple interactions 		ISO belinostat results in increased expression of TFAP2C mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFAP2C mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:181,733,419...181,741,404 		JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO belinostat results in decreased expression of TFF1 mRNA CTD PMID:27188386 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
G Tff2 trefoil factor 2 decreases expression ISO belinostat results in decreased expression of TFF2 mRNA CTD PMID:27188386 NCBI chr20:9,217,110...9,220,979
Ensembl chr20:9,217,121...9,220,979 		JBrowse link
G Tfpi tissue factor pathway inhibitor increases expression
multiple interactions 		ISO belinostat results in increased expression of TFPI mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFPI mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO belinostat results in increased expression of TGFB2 mRNA CTD PMID:23671600 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Thrb thyroid hormone receptor beta increases expression
multiple interactions 		ISO belinostat results in increased expression of THRB mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of THRB mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression ISO belinostat results in decreased expression of TIMP3 mRNA CTD PMID:26272509 NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547 		JBrowse link
G Tmem220 transmembrane protein 220 decreases expression ISO belinostat results in decreased expression of TMEM220 mRNA CTD PMID:27188386 NCBI chr10:52,218,782...52,229,302
Ensembl chr10:52,218,760...52,227,783 		JBrowse link
G Tmem221 transmembrane protein 221 decreases expression ISO belinostat results in decreased expression of TMEM221 mRNA CTD PMID:26272509 NCBI chr16:18,296,036...18,305,077
Ensembl chr16:18,295,931...18,305,246 		JBrowse link
G Tmem30b transmembrane protein 30B multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM30B mRNA
belinostat results in increased expression of TMEM30B mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 6:97,987,471...97,990,546
Ensembl chr 6:97,987,130...97,991,170 		JBrowse link
G Tmem44 transmembrane protein 44 decreases expression ISO belinostat results in decreased expression of TMEM44 mRNA CTD PMID:27188386 NCBI chr11:83,685,191...83,725,254
Ensembl chr11:83,686,015...83,721,859 		JBrowse link
G Tmem51 transmembrane protein 51 decreases expression ISO belinostat results in decreased expression of TMEM51 mRNA CTD PMID:27188386 NCBI chr 5:159,608,865...159,658,918
Ensembl chr 5:159,608,866...159,658,891 		JBrowse link
G Tmem64 transmembrane protein 64 increases expression
multiple interactions 		ISO belinostat results in increased expression of TMEM64 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TMEM64 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:33,495,992...33,542,390
Ensembl chr 5:33,496,032...33,542,389 		JBrowse link
G Tmt1b thiol methyltransferase 1B decreases expression ISO belinostat results in decreased expression of TMT1B mRNA CTD PMID:27188386 NCBI chr 7:1,973,334...1,975,980
Ensembl chr 7:1,973,337...1,975,980 		JBrowse link
G Tnc tenascin C decreases expression
multiple interactions 		ISO belinostat results in decreased expression of TNC mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TNC mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNFSF11 mRNA CTD PMID:27188386 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase increases expression
multiple interactions 		ISO belinostat results in increased expression of TNIK mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNIK mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:113,112,937...113,511,341
Ensembl chr 2:113,112,938...113,511,339 		JBrowse link
G Tnn tenascin N multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNN mRNA CTD PMID:27188386 NCBI chr13:74,852,586...74,919,789
Ensembl chr13:74,852,586...74,919,789 		JBrowse link
G Tox2 TOX high mobility group box family member 2 decreases expression
multiple interactions 		ISO belinostat results in decreased expression of TOX2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TOX2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:172,272,718...172,400,235
Ensembl chr 3:172,272,736...172,400,233 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO belinostat results in decreased expression of TP53 mRNA
belinostat results in decreased expression of TRP53 mRNA; belinostat results in decreased expression of TRP53 protein 		CTD PMID:19606018 PMID:29733868 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of TPD52L1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TPD52L1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:27,991,131...28,110,158 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO belinostat results in decreased expression of TPX2 mRNA CTD PMID:19606018 NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:161,778,742...161,820,724 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO belinostat results in decreased expression of TRIB3 mRNA CTD PMID:27188386 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Trnp1 TMF1-regulated nuclear protein 1 increases expression
multiple interactions 		ISO belinostat results in increased expression of TRNP1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRNP1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 5:150,990,312...150,997,148
Ensembl chr 5:150,989,973...150,997,277 		JBrowse link
G Ttc29 tetratricopeptide repeat domain 29 increases expression
multiple interactions 		ISO belinostat results in increased expression of TTC29 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC29 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr19:46,436,526...46,654,891
Ensembl chr19:46,424,935...46,654,870 		JBrowse link
G Tuba1a tubulin, alpha 1A affects expression ISO belinostat affects the expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:131,968,770...131,996,035 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO belinostat results in increased expression of TUFT1 mRNA CTD PMID:19606018 NCBI chr 2:184,949,437...184,995,321
Ensembl chr 2:184,949,437...184,995,383 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO belinostat results in increased expression of TWIST1 protein CTD PMID:23671600 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:56,398,061...56,404,965 		JBrowse link
G Txnrd3 thioredoxin reductase 3 decreases expression ISO belinostat results in decreased expression of TXNRD3 mRNA CTD PMID:27188386 NCBI chr 4:123,629,768...123,669,713
Ensembl chr 4:123,648,750...123,668,552 		JBrowse link
G Tyms thymidylate synthetase decreases expression ISO belinostat results in decreased expression of TYMS mRNA CTD PMID:19606018 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases glucuronidation
multiple interactions
increases glucuronidation 		ISO UGT1A1 gene polymorphism results in decreased glucuronidation of belinostat
belinostat inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Hymecromone]
UGT1A1 protein results in increased glucuronidation of belinostat 		CTD PMID:23382909 PMID:33290829 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO belinostat inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a6a UDP glucuronosyltransferase family 1 member A6a multiple interactions ISO belinostat inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [UGT1A6 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO belinostat inhibits the reaction [[UGT2B7 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Hymecromone] CTD PMID:33290829 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
G Ugt3a1 UDP glycosyltransferase family 3 member A1 increases expression
multiple interactions 		ISO belinostat results in increased expression of UGT3A1 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UGT3A1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:60,062,257...60,077,354
Ensembl chr 2:60,061,775...60,077,354 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 increases expression
multiple interactions 		ISO belinostat results in increased expression of UGT8 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UGT8 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 2:216,938,884...217,007,167
Ensembl chr 2:216,938,990...217,007,167 		JBrowse link
G Unc93a unc-93 homolog A decreases expression ISO belinostat results in decreased expression of UNC93A mRNA CTD PMID:27188386 NCBI chr 1:55,528,237...55,561,346
Ensembl chr 1:55,528,281...55,549,768 		JBrowse link
G Ung uracil-DNA glycosylase decreases expression ISO belinostat results in decreased expression of UNG mRNA CTD PMID:29733868 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 increases expression
multiple interactions 		ISO belinostat results in increased expression of USP28 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of USP28 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 8:58,222,258...58,282,711
Ensembl chr 8:58,222,220...58,282,750 		JBrowse link
G Utf1 undifferentiated embryonic cell transcription factor 1 multiple interactions
increases expression 		ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of UTF1 mRNA
belinostat results in increased expression of UTF1 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 1:204,169,954...204,171,080
Ensembl chr 1:204,169,954...204,171,080 		JBrowse link
G Uts2b urotensin 2B decreases expression ISO belinostat results in decreased expression of UTS2B mRNA CTD PMID:27188386 NCBI chr11:86,929,210...86,944,255
Ensembl chr11:86,929,210...86,944,255 		JBrowse link
G Vash2 vasohibin 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of VASH2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VASH2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr13:105,060,857...105,092,325
Ensembl chr13:105,060,857...105,092,275 		JBrowse link
G Ventx VENT homeobox increases expression
multiple interactions 		ISO belinostat results in increased expression of VENTX mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VENTX mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:90,707,273...90,708,315
Ensembl chr  X:90,706,748...90,708,555 		JBrowse link
G Veph1 ventricular zone expressed PH domain-containing 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of VEPH1 mRNA CTD PMID:27188386 NCBI chr 2:152,592,648...152,847,566
Ensembl chr 2:152,601,680...152,847,318 		JBrowse link
G Vim vimentin increases expression
multiple interactions 		ISO belinostat results in increased expression of VIM protein
pyrvinium inhibits the reaction [belinostat results in increased expression of VIM protein] 		CTD PMID:23671600 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Wfdc2 WAP four-disulfide core domain 2 increases expression
multiple interactions 		ISO belinostat results in increased expression of WFDC2 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WFDC2 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr 3:173,706,091...173,735,055
Ensembl chr 3:173,706,460...173,712,161 		JBrowse link
G Wif1 Wnt inhibitory factor 1 decreases expression ISO belinostat results in decreased expression of WIF1 mRNA CTD PMID:26272509 NCBI chr 7:58,433,326...58,503,853
Ensembl chr 7:58,384,643...58,503,852 		JBrowse link
G Wnt3a Wnt family member 3A increases expression ISO belinostat results in increased expression of WNT3A mRNA CTD PMID:23671600 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
G Wnt4 Wnt family member 4 increases expression
multiple interactions 		ISO belinostat results in increased expression of WNT4 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of WNT4 mRNA 		CTD PMID:23671600 PMID:26272509 PMID:27188386 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
G Wnt5b Wnt family member 5B decreases expression ISO belinostat results in decreased expression of WNT5B mRNA CTD PMID:26272509 NCBI chr 4:154,281,852...154,406,081
Ensembl chr 4:154,281,852...154,405,681 		JBrowse link
G Wnt7b Wnt family member 7B increases expression ISO belinostat results in increased expression of WNT7B mRNA CTD PMID:23671600 NCBI chr 7:118,514,684...118,559,316
Ensembl chr 7:118,514,684...118,559,316 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 multiple interactions ISO belinostat results in decreased degradation of and results in increased stability of and results in increased expression of WWTR1 protein; pyrvinium inhibits the reaction [belinostat results in increased expression of WWTR1 protein] CTD PMID:23671600 NCBI chr 2:143,801,181...143,916,941
Ensembl chr 2:143,801,181...143,991,950 		JBrowse link
G Xkr6 XK related 6 increases expression ISO belinostat results in increased expression of XKR6 mRNA CTD PMID:27188386 NCBI chr15:42,032,411...42,269,300
Ensembl chr15:42,033,028...42,235,591 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression ISO belinostat results in decreased expression of XRCC1 mRNA; belinostat results in decreased expression of XRCC1 protein CTD PMID:29733868 NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions ISO belinostat results in decreased expression of and results in decreased phosphorylation of YAP1 protein CTD PMID:23671600 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:13,380,551...13,451,437 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 decreases expression ISO belinostat results in decreased expression of ZBTB1 mRNA CTD PMID:27188386 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:100,838,714...100,852,643 		JBrowse link
G Zbtb38 zinc finger and BTB domain containing 38 decreases expression ISO belinostat results in decreased expression of ZBTB38 mRNA CTD PMID:27188386 NCBI chr 8:106,124,181...106,231,215
Ensembl chr 8:106,157,084...106,230,951 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions ISO [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZEB1 mRNA CTD PMID:27188386 NCBI chr17:56,644,397...56,811,155
Ensembl chr17:56,644,397...56,810,745 		JBrowse link
G Zfp185 zinc finger protein 185 decreases expression ISO belinostat results in decreased expression of ZNF185 mRNA CTD PMID:27188386 NCBI chr  X:155,874,138...155,919,921
Ensembl chr  X:155,874,127...155,917,077 		JBrowse link
G Zfp266 zinc finger protein 266 increases expression ISO belinostat results in increased expression of ZNF562 mRNA CTD PMID:27188386 NCBI chr 8:27,307,015...27,338,624
Ensembl chr 8:27,307,015...27,320,143 		JBrowse link
G Zfp36 zinc finger protein 36 decreases expression ISO belinostat results in decreased expression of ZFP36 mRNA CTD PMID:27188386 NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:92,796,628...92,799,108 		JBrowse link
G Zfp397 zinc finger protein 397 increases expression ISO belinostat results in increased expression of ZNF397 mRNA CTD PMID:27188386 NCBI chr18:15,516,514...15,523,056
Ensembl chr18:15,516,775...15,525,219 		JBrowse link
G Zfp42 zinc finger protein 42 increases expression
multiple interactions 		ISO belinostat results in increased expression of ZFP42 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZFP42 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr16:55,568,903...55,577,883
Ensembl chr16:55,568,093...55,578,170
Ensembl chr 4:55,568,093...55,578,170 		JBrowse link
G Zic3 Zic family member 3 increases expression
multiple interactions 		ISO belinostat results in increased expression of ZIC3 mRNA
[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ZIC3 mRNA 		CTD PMID:26272509 PMID:27188386 NCBI chr  X:141,159,623...141,165,587
Ensembl chr  X:141,149,594...141,170,464 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO belinostat results in increased expression of ZMAT3 mRNA CTD PMID:27188386 NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:117,034,517...117,065,294 		JBrowse link
G Zmym6 zinc finger MYM-type containing 6 decreases expression ISO belinostat results in decreased expression of ZMYM6 mRNA CTD PMID:27188386 NCBI chr 5:144,680,819...144,728,805
Ensembl chr 5:144,681,197...144,728,803 		JBrowse link
G Znf750 zinc finger protein 750 increases expression ISO belinostat results in increased expression of ZNF750 mRNA CTD PMID:26272509 NCBI chr10:107,270,926...107,279,904
Ensembl chr10:107,270,763...107,279,300 		JBrowse link
bendroflumethiazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apob apolipoprotein B affects expression ISO Bendroflumethiazide affects the expression of APOB protein CTD PMID:2344503 NCBI chr 6:36,563,704...36,603,300
Ensembl chr 6:36,563,704...36,611,814 		JBrowse link
G Ren renin increases expression ISO Bendroflumethiazide results in increased expression of REN protein CTD PMID:62162 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Slc12a3 solute carrier family 12 member 3 increases response to substance EXP SLC12A3 protein results in increased susceptibility to Bendroflumethiazide CTD PMID:18480177 NCBI chr19:10,636,594...10,690,008
Ensembl chr19:10,636,596...10,675,050 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases activity
increases secretion 		ISO Bendroflumethiazide results in decreased activity of SLC22A6 protein
SLC22A6 protein results in increased secretion of Bendroflumethiazide 		CTD PMID:18216144 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity
increases secretion 		ISO Bendroflumethiazide results in decreased activity of SLC22A8 protein
SLC22A8 protein results in increased secretion of Bendroflumethiazide 		CTD PMID:18216144 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Tpmt thiopurine S-methyltransferase decreases activity ISO Bendroflumethiazide results in decreased activity of TPMT protein CTD PMID:8866635 NCBI chr17:17,850,308...17,868,976
Ensembl chr17:17,850,279...17,868,976 		JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression EXP Bendroflumethiazide results in decreased expression of VEGFC protein CTD PMID:20625077 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
bensulfuron-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO methyl bensulfuron results in increased activity of NR1I2 protein CTD PMID:22206814 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
bosentan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
decreases expression
multiple interactions 		EXP
ISO 		bosentan metabolite results in decreased activity of ABCB11 protein; bosentan results in decreased activity of ABCB11 protein
Bosentan results in decreased expression of ABCB11 mRNA
bosentan results in decreased expression of ABCB11 mRNA
bosentan inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] 		CTD PMID:11309550 PMID:15465654 PMID:15509663 PMID:20829430 PMID:23956101 More... NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO bosentan results in decreased expression of ABCB1 mRNA CTD PMID:28369585 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO Bosentan results in decreased expression of ABCB4 mRNA CTD PMID:29761207 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
decreases expression 		EXP
ISO 		bosentan results in increased expression of ABCC2 mRNA
Bosentan results in increased expression of ABCC2 mRNA
bosentan results in decreased expression of ABCC2 mRNA 		CTD PMID:27765674 PMID:28369585 PMID:29761207 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression 		EXP
ISO 		bosentan results in increased expression of ABCC3 mRNA
bosentan results in decreased expression of ABCC3 mRNA 		CTD PMID:27765674 PMID:28369585 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression EXP bosentan results in increased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression
affects expression 		EXP
ISO 		bosentan results in increased expression of ABCG5 mRNA
Bosentan affects the expression of ABCG5 mRNA 		CTD PMID:27765674 PMID:29761207 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP bosentan results in increased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression ISO Bosentan results in decreased expression of ADH1C mRNA; Bosentan results in decreased expression of ADH1C protein CTD PMID:29761207 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Bosentan results in decreased expression of ADH4 mRNA; Bosentan results in decreased expression of ADH4 protein CTD PMID:29761207 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO bosentan inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] CTD PMID:22483689 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 affects expression ISO Bosentan affects the expression of ALDH8A1 mRNA CTD PMID:29761207 NCBI chr 1:18,003,507...18,022,952
Ensembl chr 1:18,003,514...18,023,883 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression ISO Bosentan results in decreased expression of ALDOB mRNA; Bosentan results in decreased expression of ALDOB protein CTD PMID:29761207 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 affects expression ISO Bosentan affects the expression of ASCL1 mRNA CTD PMID:29761207 NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:23,790,360...23,798,231 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO bosentan inhibits the reaction [Doxorubicin results in increased expression of BAX protein] CTD PMID:17974986 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G C3h15orf48 similar to human chromosome 15 open reading frame 48 affects expression ISO Bosentan affects the expression of COXFA4L3 mRNA CTD PMID:29761207 NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089 		JBrowse link
G C9 complement C9 affects expression ISO Bosentan affects the expression of C9 mRNA CTD PMID:29761207 NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752 		JBrowse link
G Ca12 carbonic anhydrase 12 affects expression ISO Bosentan affects the expression of CA12 mRNA CTD PMID:29761207 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP Bosentan inhibits the reaction [Fluorouracil results in increased cleavage of CASP3 protein] CTD PMID:34800596 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase decreases expression ISO Bosentan results in decreased expression of CAT mRNA CTD PMID:29761207 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression ISO bosentan results in decreased expression of COL1A2 protein CTD PMID:11729239 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression ISO Bosentan results in decreased expression of CPS1 mRNA; Bosentan results in decreased expression of CPS1 protein CTD PMID:29761207 NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule decreases expression
multiple interactions 		ISO bosentan results in decreased expression of CXADR mRNA; bosentan results in decreased expression of CXADR protein
EDN1 protein inhibits the reaction [bosentan results in decreased expression of CXADR mRNA] 		CTD PMID:20392896 NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Bosentan results in increased expression of CYP2B6 mRNA CTD PMID:18332078 PMID:29761207 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 affects expression ISO Bosentan affects the expression of CYP3A43 mRNA CTD PMID:29761207 NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Bosentan results in increased expression of CYP3A4 mRNA CTD PMID:18332078 PMID:29761207 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO Bosentan results in decreased expression of CYP7A1 mRNA CTD PMID:29761207 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Dclk1 doublecortin-like kinase 1 affects expression ISO Bosentan affects the expression of DCLK1 mRNA CTD PMID:29761207 NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090 		JBrowse link
G Dlx6 distal-less homeobox 6 decreases expression ISO bosentan results in decreased expression of DLX6 mRNA CTD PMID:15063187 NCBI chr 4:35,951,005...35,956,354
Ensembl chr 4:35,951,005...35,956,354 		JBrowse link
G Edn1 endothelin 1 decreases activity
decreases expression
multiple interactions 		EXP
ISO 		bosentan results in decreased activity of EDN1 protein
bosentan results in decreased expression of EDN1 protein
bosentan inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA]; bosentan inhibits the reaction [Oxotremorine results in increased activity of EDN1 protein]; bosentan inhibits the reaction [TGFB1 protein results in increased activity of EDN1 protein]; EDN1 protein inhibits the reaction [bosentan results in decreased expression of CXADR mRNA]
3,5-dibromosalicylic acid inhibits the reaction [bosentan inhibits the reaction [EDN1 protein binds to EDNRA protein]]; bosentan binds to and results in decreased activity of EDN1 protein; bosentan inhibits the reaction [EDN1 protein binds to EDNRA protein]; bosentan inhibits the reaction [Monocrotaline results in increased expression of EDN1 mRNA] 		CTD PMID:10474778 PMID:10961375 PMID:11093786 PMID:16431896 PMID:20392896 More... NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Edn3 endothelin 3 decreases activity EXP bosentan results in decreased activity of EDN3 protein CTD PMID:10961375 NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329 		JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO
EXP 		bosentan binds to and results in decreased activity of EDNRA protein
3,5-dibromosalicylic acid inhibits the reaction [bosentan inhibits the reaction [EDN1 protein binds to EDNRA protein]]; bosentan binds to and results in decreased activity of EDNRA protein; bosentan inhibits the reaction [EDN1 protein binds to EDNRA protein] 		CTD PMID:11093786 PMID:15964565 PMID:16219361 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO bosentan binds to and results in decreased activity of EDNRB protein CTD PMID:16219361 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Bosentan results in decreased expression of FABP1 mRNA; Bosentan results in decreased expression of FABP1 protein CTD PMID:29761207 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO bosentan inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; bosentan inhibits the reaction [Glucose results in increased expression of FN1 protein] CTD PMID:12388107 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G G0s2 G0/G1switch 2 affects expression ISO Bosentan affects the expression of G0S2 mRNA CTD PMID:29761207 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression ISO Bosentan affects the expression of G6PC1 mRNA CTD PMID:29761207 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Gata4 GATA binding protein 4 multiple interactions
affects activity 		ISO
EXP 		bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 mRNA]; bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]
bosentan affects the activity of GATA4 protein 		CTD PMID:17974986 PMID:21084678 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Bosentan results in increased expression of GCLC mRNA CTD PMID:29761207 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Bosentan inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein] CTD PMID:33026618 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO Bosentan results in decreased expression of GPX1 mRNA CTD PMID:29761207 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 decreases expression ISO Bosentan results in decreased expression of GSTT2 mRNA CTD PMID:29761207 NCBI chr20:12,819,053...12,822,724
Ensembl chr20:12,818,540...12,822,718 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Bosentan results in increased expression of HMOX1 mRNA CTD PMID:29761207 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO Bosentan results in decreased expression of HNF4A mRNA CTD PMID:29761207 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 affects expression ISO Bosentan affects the expression of HSD3B1 mRNA CTD PMID:29761207 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Igf1 insulin-like growth factor 1 affects expression ISO Bosentan affects the expression of IGF1 mRNA CTD PMID:29761207 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il6 interleukin 6 increases expression ISO Bosentan results in increased expression of IL6 mRNA CTD PMID:29761207 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inhbe inhibin subunit beta E affects expression ISO Bosentan affects the expression of INHBE mRNA CTD PMID:29761207 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519 		JBrowse link
G Kmo kynurenine 3-monooxygenase affects expression ISO Bosentan affects the expression of KMO mRNA CTD PMID:29761207 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151 		JBrowse link
G Leap2 liver enriched antimicrobial peptide 2 affects expression ISO Bosentan affects the expression of LEAP2 mRNA CTD PMID:29761207 NCBI chr10:38,081,001...38,082,073
Ensembl chr10:38,081,001...38,082,073 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression ISO Bosentan results in decreased expression of MGST1 mRNA CTD PMID:29761207 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875 		JBrowse link
G Mrc1 mannose receptor, C type 1 affects expression ISO Bosentan affects the expression of MRC1 mRNA CTD PMID:29761207 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Bosentan results in decreased expression of MTTP mRNA CTD PMID:29761207 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP Bosentan inhibits the reaction [Fluorouracil results in increased expression of MYD88 protein] CTD PMID:34800596 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions ISO Bosentan inhibits the reaction [MYH7 gene mutant form results in increased expression of NPPB protein] CTD PMID:29741611 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Nfix nuclear factor I X decreases expression ISO Bosentan results in decreased expression of NFIX mRNA CTD PMID:29761207 NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP Bosentan inhibits the reaction [Fluorouracil results in decreased expression of NOS3 protein] CTD PMID:34800596 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nox4 NADPH oxidase 4 decreases expression ISO Bosentan results in decreased expression of NOX4 mRNA CTD PMID:29761207 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Bosentan inhibits the reaction [MYH7 gene mutant form results in increased expression of NPPB protein] CTD PMID:29741611 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Bosentan results in increased expression of NQO1 mRNA CTD PMID:29761207 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 decreases expression ISO Bosentan results in decreased expression of NR1H2 mRNA CTD PMID:29761207 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 decreases expression ISO Bosentan results in decreased expression of NR1H3 mRNA CTD PMID:29761207 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO Bosentan results in decreased expression of NR1H4 mRNA CTD PMID:29761207 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO Bosentan results in decreased expression of PCK2 mRNA CTD PMID:29761207 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864 		JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 affects expression ISO Bosentan affects the expression of PGLYRP2 mRNA CTD PMID:29761207 NCBI chr 7:12,069,414...12,082,437
Ensembl chr 7:12,069,414...12,078,369 		JBrowse link
G Pklr pyruvate kinase L/R affects expression ISO Bosentan affects the expression of PKLR mRNA CTD PMID:29761207 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pon1 paraoxonase 1 decreases expression ISO Bosentan results in decreased expression of PON1 mRNA CTD PMID:29761207 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924 		JBrowse link
G Por cytochrome p450 oxidoreductase affects expression ISO Bosentan affects the expression of POR mRNA CTD PMID:29761207 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Bosentan results in decreased expression of PPARG mRNA CTD PMID:29761207 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO Bosentan results in decreased expression of PPARGC1A mRNA CTD PMID:29761207 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ptgis prostaglandin I2 synthase multiple interactions EXP Bosentan inhibits the reaction [Monocrotaline increases expression of Ptgis mRNA in lung] RGD PMID:18612919 RGD:401901264 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP 		bosentan inhibits the reaction [Glucose results in increased activity of RELA protein]
Bosentan inhibits the reaction [Fluorouracil results in increased expression of RELA protein] 		CTD PMID:12388107 PMID:34800596 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions EXP Bosentan inhibits the reaction [Nitric Oxide Donors results in decreased expression of SFTPA1 mRNA]; Bosentan inhibits the reaction [Nitric Oxide results in decreased expression of SFTPA1 mRNA]; Bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA] CTD PMID:15640287 NCBI chr16:17,042,264...17,045,770
Ensembl chr16:17,042,255...17,045,769 		JBrowse link
G Sftpb surfactant protein B multiple interactions EXP bosentan inhibits the reaction [Nitric Oxide Donors results in decreased expression of SFTPB mRNA]; bosentan inhibits the reaction [Nitric Oxide results in decreased expression of SFTPB mRNA]; bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA] CTD PMID:15640287 NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:105,917,578...105,927,646 		JBrowse link
G Sftpc surfactant protein C multiple interactions EXP bosentan inhibits the reaction [Nitric Oxide Donors results in decreased expression of SFTPC mRNA]; bosentan inhibits the reaction [Nitric Oxide results in decreased expression of SFTPC mRNA]; bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPC mRNA] CTD PMID:15640287 NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP
ISO 		bosentan results in decreased expression of SLC10A1 mRNA
Bosentan results in decreased expression of SLC10A1 mRNA 		CTD PMID:27765674 PMID:28369585 PMID:29761207 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 affects expression ISO Bosentan affects the expression of SLC22A7 mRNA CTD PMID:29761207 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Bosentan results in increased expression of SLC3A2 mRNA; Bosentan results in increased expression of SLC3A2 protein CTD PMID:29761207 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc51a solute carrier family 51 member A increases expression ISO Bosentan results in increased expression of SLC51A mRNA CTD PMID:29761207 NCBI chr11:81,804,141...81,818,539
Ensembl chr11:81,803,972...81,818,539 		JBrowse link
G Slc51b SLC51 subunit beta increases expression ISO Bosentan results in increased expression of SLC51B mRNA CTD PMID:29761207 NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109 		JBrowse link
G Slc6a1 solute carrier family 6 member 1 affects expression ISO Bosentan affects the expression of SLC6A1 mRNA CTD PMID:29761207 NCBI chr 4:149,004,447...149,037,840
Ensembl chr 4:149,004,635...149,037,839 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP Bosentan results in decreased expression of SLCO1A1 mRNA CTD PMID:27765674 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 multiple interactions
increases uptake 		EXP [biochanin A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [hispidulin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [isoliquiritigenin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [kaempferol results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [licochalcone A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [Luteolin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [sinensetin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan
SLCO1B1 protein results in increased uptake of Bosentan 		CTD PMID:32259555 NCBI chr 4:176,197,736...176,244,401
Ensembl chr 4:176,197,741...176,244,395 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO Bosentan results in decreased expression of SOD1 mRNA CTD PMID:29761207 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Bosentan results in increased expression of SOD2 mRNA CTD PMID:29761207 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 affects expression ISO Bosentan affects the expression of SULT1E1 mRNA CTD PMID:29761207 NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716 		JBrowse link
G Tat tyrosine aminotransferase affects expression ISO Bosentan affects the expression of TAT mRNA CTD PMID:29761207 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO bosentan inhibits the reaction [TGFB1 protein results in increased activity of EDN1 protein] CTD PMID:22796455 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Bosentan inhibits the reaction [Fluorouracil results in increased expression of TLR4 protein] CTD PMID:34800596 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO bosentan inhibits the reaction [Doxorubicin results in increased expression of TNF protein] CTD PMID:17974986 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnni1 troponin I1, slow skeletal type multiple interactions EXP Bosentan inhibits the reaction [Fluorouracil results in increased expression of TNNI1 protein] CTD PMID:34800596 NCBI chr13:49,781,529...49,793,385
Ensembl chr13:49,780,951...49,793,390 		JBrowse link
G Txn2 thioredoxin 2 decreases expression ISO Bosentan results in decreased expression of TXN2 mRNA CTD PMID:29761207 NCBI chr 7:111,377,338...111,390,940
Ensembl chr 7:111,386,805...111,390,022 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Bosentan results in increased expression of TXNRD1 mRNA CTD PMID:29761207 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Ugt1a6a UDP glucuronosyltransferase family 1 member A6a decreases expression ISO Bosentan results in decreased expression of UGT1A6 mRNA CTD PMID:29761207 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Vnn1 vanin 1 affects expression ISO Bosentan affects the expression of VNN1 mRNA CTD PMID:29761207 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629 		JBrowse link
G Xdh xanthine dehydrogenase decreases expression ISO Bosentan results in decreased expression of XDH mRNA CTD PMID:29761207 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
brinzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgap45 Rho GTPase activating protein 45 affects expression ISO brinzolamide affects the expression of ARHGAP45 mRNA CTD PMID:25811541 NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO brinzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO brinzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 affects expression ISO brinzolamide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:3,261,656...3,265,548 JBrowse link
bumetanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Bumetanide CTD PMID:17939016 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Cftr CF transmembrane conductance regulator decreases activity ISO Bumetanide results in decreased activity of CFTR protein CTD PMID:15131065 PMID:15802612 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Bumetanide inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO
EXP 		Bumetanide inhibits the reaction [SLC12A2 gene mutant form promotes the reaction [Glucose results in increased secretion of INS1 protein]]
Bumetanide inhibits the reaction [Glucose results in increased secretion of INS1 protein] 		CTD PMID:22872759 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO Bumetanide results in increased expression of PTGS1 mRNA CTD PMID:14504926 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ren renin multiple interactions
increases expression
increases secretion 		ISO [Bumetanide co-treated with trandolapril] results in increased expression of REN protein; Indomethacin inhibits the reaction [Bumetanide results in increased activity of REN protein]; Probenecid inhibits the reaction [Bumetanide results in increased secretion of REN protein]
Bumetanide results in increased expression of REN mRNA
Bumetanide results in increased expression of REN protein 		CTD PMID:6756707 PMID:7040495 PMID:14504926 PMID:16635047 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Bumetanide affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases response to substance
multiple interactions
decreases activity 		ISO
EXP 		SLC12A2 results in increased susceptibility to Bumetanide
Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]
Bumetanide results in decreased activity of SLC12A2 protein
[calyculin A results in increased phosphorylation of SLC12A2 protein] inhibits the reaction [Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]]; Bumetanide inhibits the reaction [Manganese results in increased expression of SLC12A2 protein]; Bumetanide inhibits the reaction [Manganese results in increased oxidation of SLC12A2 protein]; Bumetanide inhibits the reaction [Manganese results in increased phosphorylation of and results in increased activity of SLC12A2 protein]; Bumetanide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium]
Bumetanide inhibits the reaction [SLC12A2 gene mutant form promotes the reaction [Glucose results in increased secretion of INS1 protein]]
Bumetanide results in decreased activity of SLC12A2 protein; Bumetanide results in decreased activity of SLC12A2 protein mutant form 		CTD PMID:12556450 PMID:14630635 PMID:16709721 PMID:17259435 PMID:22872759 More... NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO Bumetanide results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957 		JBrowse link
G Slc17a3 solute carrier family 17 member 3 affects transport ISO SLC17A3 gene SNP affects the transport of Bumetanide CTD PMID:21282933 NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity 		EXP Bumetanide inhibits the reaction [SLC19A1 protein affects the transport of Methotrexate]
Bumetanide results in decreased activity of SLC19A1 protein 		CTD PMID:14612385 NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,583,929...11,601,488 		JBrowse link
G Slc22a19 solute carrier family 22, member 19 multiple interactions EXP Bumetanide inhibits the reaction [SLC22A19 protein affects the transport of estrone sulfate] CTD PMID:16079298 NCBI chr 1:214,339,594...214,394,681
Ensembl chr 1:214,339,599...214,394,681 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions
increases transport 		ISO Bumetanide inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline]
SLC22A7 protein results in increased transport of Bumetanide 		CTD PMID:15901346 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP
ISO 		Bumetanide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
Bumetanide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate] 		CTD PMID:10224140 PMID:11306713 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
celecoxib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions 		ISO Celecoxib results in decreased activity of ABCB11 protein
Celecoxib inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] 		CTD PMID:22646477 PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases methylation
decreases activity
increases expression
multiple interactions 		ISO Celecoxib results in decreased expression of ABCB1 protein
Celecoxib results in increased methylation of ABCB1 promoter
Celecoxib results in decreased activity of ABCB1A protein
Celecoxib results in increased expression of ABCB1 mRNA
[Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Tamoxifen 		CTD PMID:15458769 PMID:19562670 PMID:21745461 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression
increases expression 		ISO Celecoxib results in decreased expression of ABCC1 mRNA
Celecoxib results in increased expression of ABCC1 mRNA 		CTD PMID:18202791 PMID:21745461 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity ISO Celecoxib results in decreased activity of ABCC2 protein CTD PMID:22646477 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases activity 		ISO Celecoxib results in increased expression of ABCC4 mRNA; Celecoxib results in increased expression of ABCC4 protein
Celecoxib results in decreased activity of ABCC4 protein 		CTD PMID:18690847 PMID:39023798 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Celecoxib results in increased expression of ABCC5 mRNA; Celecoxib results in increased expression of ABCC5 protein CTD PMID:18690847 NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655 		JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 affects expression ISO Celecoxib affects the expression of ABCF1 mRNA CTD PMID:20562220 NCBI chr20:2,807,315...2,820,240
Ensembl chr20:2,807,106...2,820,240 		JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 affects expression ISO Celecoxib affects the expression of ABCF2 mRNA CTD PMID:20562220 NCBI chr 4:11,485,865...11,500,067
Ensembl chr 4:11,487,395...11,500,053 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression ISO Celecoxib results in decreased expression of ABCG2 mRNA CTD PMID:18202791 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Acan aggrecan affects expression EXP Celecoxib affects the expression of ACAN mRNA CTD PMID:16273290 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity 		ISO donepezil inhibits the reaction [Celecoxib results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Celecoxib results in increased activity of ACHE protein] CTD PMID:18208924 PMID:18343489 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression 		EXP Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Celecoxib results in decreased expression of ACTA2 mRNA; Celecoxib results in decreased expression of ACTA2 protein 		CTD PMID:16420518 PMID:19201774 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Akap1 A-kinase anchoring protein 1 affects expression ISO Celecoxib affects the expression of AKAP1 mRNA CTD PMID:20562220 NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases response to substance
multiple interactions
decreases expression
affects phosphorylation
decreases phosphorylation
decreases activity
increases phosphorylation 		ISO
EXP 		AKT1 protein results in decreased susceptibility to Celecoxib
[Celecoxib co-treated with sulindac sulfone] results in decreased expression of AKT1 protein; [Celecoxib co-treated with sulindac sulfone] results in decreased expression of AKT1 protein modified form; Celecoxib inhibits the reaction [PDGFA results in increased phosphorylation of and results in increased activity of AKT1 protein]
Celecoxib results in decreased expression of AKT1 protein
Celecoxib affects the phosphorylation of AKT1 protein
Celecoxib analog results in decreased phosphorylation of AKT1 protein; Celecoxib results in decreased phosphorylation of AKT1 protein
Celecoxib results in decreased activity of AKT1 protein
Celecoxib analog results in increased phosphorylation of AKT1 protein; Celecoxib results in increased phosphorylation of AKT1 protein
[Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of AKT1 protein; [Celecoxib co-treated with Docetaxel] results in decreased phosphorylation of AKT1 protein; [Celecoxib co-treated with tetracycline CMT-3] results in decreased phosphorylation of AKT1 protein; Celecoxib inhibits the reaction [PDGFA results in increased phosphorylation of and results in increased activity of AKT1 protein]; Celecoxib results in decreased phosphorylation of and results in decreased activity of AKT1 protein 		CTD PMID:10753955 PMID:12000750 PMID:12464646 PMID:14654083 PMID:15499625 More... NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin multiple interactions EXP Celecoxib inhibits the reaction [Gentamicins results in decreased expression of ALB protein] CTD PMID:31628940 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects localization EXP celecoxib increases the release of aldh2 protein from the mitochondrial matrix RGD PMID:29491208 RGD:15036803 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects expression ISO Celecoxib affects the expression of ALDOC mRNA CTD PMID:20562220 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO Celecoxib inhibits the reaction [Butylated Hydroxytoluene affects the localization of ALOX5 protein] CTD PMID:12376474 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126 		JBrowse link
G Apod apolipoprotein D multiple interactions ISO [Celecoxib co-treated with Paraquat] results in increased expression of APOD mRNA; Celecoxib inhibits the reaction [Oxidopamine results in decreased expression of APOD mRNA] CTD PMID:33160981 NCBI chr11:82,936,216...82,957,264
Ensembl chr11:82,936,038...82,957,263 		JBrowse link
G App amyloid beta precursor protein affects cleavage ISO Celecoxib affects the cleavage of APP protein CTD PMID:14690522 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression 		EXP
ISO 		[Celecoxib co-treated with sulindac sulfone] results in decreased expression of AR protein
Celecoxib results in decreased expression of AR protein 		CTD PMID:15570007 PMID:17908994 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression ISO Celecoxib affects the expression of ATP6AP2 mRNA CTD PMID:20562220 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875 		JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) affects expression ISO Celecoxib affects the expression of ATP9A mRNA CTD PMID:20562220 NCBI chr 3:177,779,203...177,886,431
Ensembl chr 3:177,779,203...178,023,661 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
decreases response to substance 		ISO
EXP 		Celecoxib analog results in increased expression of BAK1 protein; Celecoxib results in increased expression of BAK1 mRNA; Celecoxib results in increased expression of BAK1 protein
BAK1 results in decreased susceptibility to Celecoxib 		CTD PMID:18349538 PMID:19428934 PMID:19682443 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions
increases activity 		ISO Celecoxib results in decreased expression of BAX mRNA
Celecoxib results in increased expression of BAX protein
[docetaxel co-treated with Celecoxib] results in increased expression of BAX protein; [tetracycline CMT-3 co-treated with Celecoxib] results in increased expression of BAX protein; BBC3 mutant form inhibits the reaction [Celecoxib results in increased activity of and results in increased localization of BAX protein]; Celecoxib results in increased activity of and results in increased localization of BAX protein
Celecoxib results in increased activity of BAX protein 		CTD PMID:15688368 PMID:17342322 PMID:17368424 PMID:17952603 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases response to substance
increases expression
multiple interactions 		ISO BBC3 results in increased susceptibility to Celecoxib
Celecoxib results in increased expression of BBC3; Celecoxib results in increased expression of BBC3 protein
BBC3 mutant form inhibits the reaction [Celecoxib results in increased activity of and results in increased localization of BAX protein]; TP53 protein promotes the reaction [Celecoxib results in increased expression of BBC3 protein] 		CTD PMID:17368424 PMID:18760266 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member multiple interactions ISO Celecoxib results in increased cleavage of and results in increased localization of BCAR1 protein CTD PMID:16353145 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression 		ISO BCL2 protein inhibits the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]; BCL2 protein inhibits the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]]; BCL2 protein inhibits the reaction [Celecoxib results in increased cleavage of CASP3 protein]; Celecoxib promotes the reaction [docetaxel results in increased expression of BCL2 protein]; Celecoxib promotes the reaction [tetracycline CMT-3 results in increased expression of BCL2 protein]; tetraarsenic tetrasulfide promotes the reaction [Celecoxib results in decreased expression of BCL2 protein]
Celecoxib promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of BCL2 protein]
Celecoxib results in increased expression of BCL2 mRNA 		CTD PMID:15688368 PMID:15911099 PMID:16230411 PMID:16391871 PMID:17342322 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression 		ISO [Celecoxib co-treated with docetaxel] results in decreased expression of BCL2L1 protein; [Celecoxib co-treated with tetracycline CMT-3] results in decreased expression of BCL2L1 protein; BCL2L1 mutant form promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]
Celecoxib results in increased expression of BCL2L1 mRNA
Celecoxib results in decreased expression of BCL2L1 protein 		CTD PMID:15688368 PMID:17342322 PMID:20104024 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions 		ISO Celecoxib results in increased cleavage of BID protein
[ABT-737 co-treated with Celecoxib] results in increased cleavage of BID protein; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of BID protein] 		CTD PMID:15197583 PMID:15572759 PMID:20104024 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
decreases expression
affects binding 		ISO [Celecoxib binds to BIRC5 promoter] which results in decreased expression of BIRC5 mRNA; BIRC5 protein inhibits the reaction [Celecoxib results in increased activity of CASP3 protein]
[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein
Celecoxib results in increased expression of BIRC5 mRNA
Celecoxib results in decreased expression of BIRC5 mRNA; Celecoxib results in decreased expression of BIRC5 protein 		CTD PMID:16004971 PMID:16123214 PMID:16707021 PMID:17270149 PMID:17342322 More... NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO Celecoxib binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity 		ISO Celecoxib binds to and results in decreased activity of CA2 protein
Celecoxib results in decreased activity of CA2 protein 		CTD PMID:16858005 PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Casp3 caspase 3 decreases expression
multiple interactions
increases activity
increases cleavage
increases expression 		ISO
EXP 		Celecoxib analog results in decreased expression of CASP3 protein; Celecoxib results in decreased expression of CASP3 protein
Celecoxib inhibits the reaction [aristolochic acid I results in increased cleavage of CASP3 protein]; Celecoxib inhibits the reaction [Freund's Adjuvant results in increased activity of CASP3 protein]; Celecoxib inhibits the reaction [Gentamicins results in increased expression of CASP3 protein]
Celecoxib results in increased activity of CASP3 protein
Celecoxib results in increased cleavage of CASP3 protein
Celecoxib results in increased expression of CASP3 protein
3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]; 3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]]; 3-methyladenine promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]; [ABT-737 co-treated with Celecoxib] results in increased activity of CASP3 protein; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of and results in increased activity of CASP3 protein; ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]; ABT-737 promotes the reaction [Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]; BCL2 protein inhibits the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]; BCL2 protein inhibits the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]]; BCL2 protein inhibits the reaction [Celecoxib results in increased cleavage of CASP3 protein]; BCL2L1 mutant form promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]]; BIRC5 protein inhibits the reaction [Celecoxib results in increased activity of CASP3 protein]; Celecoxib analog results in increased cleavage of and results in increased activity of CASP3 protein; Celecoxib inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein]; Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP3 protein]; Celecoxib promotes the reaction [Docetaxel results in increased activity of and results in increased expression of CASP3 protein]; Celecoxib promotes the reaction [tetracycline CMT-3 results in increased activity of and results in increased expression of CASP3 protein]; Celecoxib results in increased activity of and results in increased expression of CASP3 protein; Celecoxib results in increased cleavage of and results in increased activity of CASP3 protein; Docetaxel promotes the reaction [Celecoxib results in increased activity of and results in increased expression of CASP3 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP3 protein]; MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP3 protein]; PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP3 protein]; tetracycline CMT-3 promotes the reaction [Celecoxib results in increased activity of and results in increased expression of CASP3 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP3 protein]; Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP3 protein]
Celecoxib results in increased activity of CASP3; Celecoxib results in increased activity of CASP3 protein 		CTD PMID:10753955 PMID:12824303 PMID:15197583 PMID:15499625 PMID:15572759 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp6 caspase 6 multiple interactions ISO Celecoxib results in increased cleavage of and results in increased activity of CASP6 protein; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP6 protein] CTD PMID:15572759 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
affects activity 		ISO Celecoxib results in increased activity of CASP7; Celecoxib results in increased activity of CASP7 protein
Celecoxib results in increased cleavage of and results in increased activity of CASP7 protein; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP7 protein]
Celecoxib analog affects the activity of CASP7 protein 		CTD PMID:15572759 PMID:18202791 PMID:18485224 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases activity 		ISO 3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]]; 3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP8 protein]]; 3-methyladenine promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]; [ABT-737 co-treated with Celecoxib] results in increased activity of CASP8 protein; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP8 protein; ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]; ABT-737 promotes the reaction [Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP8 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP8 protein]]; Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP8 protein]; Celecoxib results in increased cleavage of and results in increased activity of CASP8 protein; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP8 protein]; MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP8 protein]; PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP8 protein]; TNFRSF10B mutant form inhibits the reaction [Celecoxib results in increased cleavage of CASP8 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP8 protein]; Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP8 protein]
Celecoxib analog results in increased activity of CASP8 protein; Celecoxib results in increased activity of CASP8 protein 		CTD PMID:12824303 PMID:15197583 PMID:15499625 PMID:15572759 PMID:18172863 More... NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases cleavage 		ISO 3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]]; 3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP9 protein]]; 3-methyladenine promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]; [ABT-737 co-treated with Celecoxib] results in increased activity of CASP9 protein; [Atorvastatin co-treated with Celecoxib] results in increased cleavage of CASP9 protein; ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]; ABT-737 promotes the reaction [Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [3-methyladenine promotes the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP9 protein]]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ABT-737 promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]]; benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP9 protein]]; Celecoxib analog results in increased cleavage of and results in increased activity of CASP9 protein; Celecoxib promotes the reaction [ABT-737 results in increased cleavage of CASP9 protein]; Celecoxib promotes the reaction [Docetaxel results in increased cleavage of and results in increased activity of CASP9 protein]; Celecoxib promotes the reaction [tetracycline CMT-3 results in increased cleavage of and results in increased activity of CASP9 protein]; Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein; Docetaxel promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP9 protein]; PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP9 protein]; tetracycline CMT-3 promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; Wortmannin promotes the reaction [Celecoxib results in increased cleavage of CASP9 protein]
Celecoxib results in increased activity of CASP9 protein 		CTD PMID:12824303 PMID:15197583 PMID:15499625 PMID:15572759 PMID:15688368 More... Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases expression
multiple interactions 		ISO Celecoxib results in decreased expression of CAT protein
Celecoxib inhibits the reaction [Smoke results in increased activity of CAT protein] 		CTD PMID:18848576 PMID:21280565 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 increases expression ISO Celecoxib results in increased expression of CAV1 protein CTD PMID:18848576 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression 		ISO
EXP 		Celecoxib inhibits the reaction [lead acetate results in increased secretion of CCL2 protein]
Celecoxib inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein]
Celecoxib results in decreased expression of CCL2 mRNA 		CTD PMID:12902868 PMID:20039930 PMID:24530660 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Celecoxib results in decreased expression of CCL5 mRNA CTD PMID:12902868 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccnb1 cyclin B1 affects expression ISO Celecoxib affects the expression of CCNB1 CTD PMID:19846907 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnd1 cyclin D1 affects expression
multiple interactions
decreases expression 		ISO
EXP 		Celecoxib affects the expression of CCND1
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of CCND1 protein]
[Celecoxib co-treated with sulindac sulfone] results in decreased expression of CCND1 protein
Celecoxib inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Celecoxib promotes the reaction [Gemcitabine results in decreased expression of CCND1 protein]
Celecoxib results in decreased expression of CCND1 mRNA; Celecoxib results in decreased expression of CCND1 protein 		CTD PMID:15489888 PMID:16060994 PMID:17270149 PMID:17908994 PMID:19846907 More... NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd2 cyclin D2 decreases expression ISO Celecoxib results in decreased expression of CCND2 mRNA; Celecoxib results in decreased expression of CCND2 protein CTD PMID:19428934 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression ISO Celecoxib results in decreased expression of CCR2 mRNA CTD PMID:12902868 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 decreases expression ISO Celecoxib results in decreased expression of CCR5 mRNA CTD PMID:12902868 NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594 		JBrowse link
G Cd2ap CD2-associated protein multiple interactions EXP Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of CD2AP mRNA] CTD PMID:19194550 NCBI chr 9:25,580,071...25,679,968
Ensembl chr 9:25,583,975...25,679,968 		JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
affects expression 		ISO Celecoxib analog results in increased expression of CDH1 protein; Celecoxib results in increased expression of CDH1 mRNA; Celecoxib results in increased expression of CDH1 protein
Celecoxib inhibits the reaction [SNAI1 protein binds to CDH1 promoter]
Celecoxib affects the expression of CDH1 protein 		CTD PMID:17224647 PMID:19682443 PMID:29932878 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Celecoxib results in decreased expression of CDK2 protein; Celecoxib results in decreased expression of CDK2 protein modified form CTD PMID:16136956 PMID:19428934 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Celecoxib results in decreased expression of CDK4 protein CTD PMID:16136956 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases localization
increases expression 		ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein; Celecoxib promotes the reaction [Valproic Acid results in increased expression of CDKN1A protein]; TP53 affects the reaction [Celecoxib results in increased expression of CDKN1A mRNA]; Valproic Acid promotes the reaction [Celecoxib results in increased expression of CDKN1A protein]
Celecoxib results in increased localization of CDKN1A protein
Celecoxib results in increased expression of CDKN1A mRNA; Celecoxib results in increased expression of CDKN1A protein 		CTD PMID:16136956 PMID:18172863 PMID:19141979 PMID:19706164 PMID:21737646 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression 		ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1B protein; Celecoxib promotes the reaction [Valproic Acid results in increased expression of CDKN1B protein]; Valproic Acid promotes the reaction [Celecoxib results in increased expression of CDKN1B protein]
Celecoxib results in increased expression of CDKN1B mRNA; Celecoxib results in increased expression of CDKN1B protein 		CTD PMID:18172863 PMID:19428934 PMID:21737646 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP Celecoxib inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA] CTD PMID:19247274 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO Celecoxib results in decreased expression of CFLAR CTD PMID:17145853 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Celecoxib inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Col10a1 collagen type X alpha 1 chain multiple interactions ISO [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 mRNA; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 protein CTD PMID:27050768 NCBI chr20:39,737,536...39,744,518
Ensembl chr20:39,716,822...39,751,440 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
decreases expression 		EXP Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]
Celecoxib results in decreased expression of COL1A1 mRNA 		CTD PMID:16420518 PMID:19201774 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of CREB1 protein] CTD PMID:32416088 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crp C-reactive protein decreases expression ISO Celecoxib results in decreased expression of CRP CTD PMID:12551863 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of CRYAB mRNA] CTD PMID:16420518 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Ctnnb1 catenin beta 1 affects localization ISO Celecoxib affects the localization of CTNNB1 protein; Celecoxib analog affects the localization of CTNNB1 protein CTD PMID:19682443 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsd cathepsin D multiple interactions ISO [Celecoxib co-treated with Paraquat] results in increased expression of CTSD mRNA; Celecoxib inhibits the reaction [Oxidopamine results in decreased expression of CTSD mRNA]; Celecoxib inhibits the reaction [Paraquat results in increased expression of CTSD mRNA] CTD PMID:33160981 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 decreases expression ISO Celecoxib results in decreased expression of CXCR1 mRNA CTD PMID:12902868 NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:83,215,292...83,226,872 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression ISO Celecoxib results in decreased expression of CXCR2 mRNA CTD PMID:12902868 NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression 		ISO Celecoxib results in decreased activity of CYP19A1 protein
Celecoxib results in decreased expression of CYP19A1 mRNA 		CTD PMID:15964185 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Celecoxib results in decreased activity of CYP1A2 protein CTD PMID:18816299 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Celecoxib results in decreased activity of CYP3A4 protein CTD PMID:39023798 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Dap3 death associated protein 3 affects expression ISO Celecoxib affects the expression of DAP3 mRNA CTD PMID:20562220 NCBI chr 2:176,617,151...176,645,293
Ensembl chr 2:176,617,155...176,644,270 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
affects expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 protein]; [epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 mRNA; [epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 protein; U 0126 inhibits the reaction [[epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 mRNA]; U 0126 inhibits the reaction [[epigallocatechin gallate co-treated with Celecoxib] results in increased expression of DDIT3 protein]
Celecoxib results in increased expression of DDIT3; Celecoxib results in increased expression of DDIT3 protein
Celecoxib analog affects the expression of DDIT3 protein 		CTD PMID:16463383 PMID:18485224 PMID:20104024 PMID:21567098 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Des desmin multiple interactions
increases expression 		ISO PTGS2 protein affects the reaction [Celecoxib results in increased expression of DES mRNA] CTD PMID:18089846 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha multiple interactions ISO TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of DFFA protein] CTD PMID:15572759 NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression ISO Celecoxib affects the expression of DHCR24 mRNA CTD PMID:20562220 NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP Celecoxib inhibits the reaction [Cyclosporine results in increased expression of EDNRA protein] CTD PMID:25656942 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP Celecoxib inhibits the reaction [BQ 788 results in decreased expression of EDNRB protein]; Celecoxib inhibits the reaction [Cyclosporine results in decreased expression of EDNRB protein]; Celecoxib inhibits the reaction [Cyclosporine results in increased expression of EDNRB protein]; Celecoxib results in decreased susceptibility to [BQ 788 binds to and results in decreased activity of EDNRB protein] CTD PMID:24462674 PMID:25656942 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein; [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein modified form; Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 PMID:17908994 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Emc3 ER membrane protein complex subunit 3 affects expression ISO Celecoxib affects the expression of EMC3 mRNA CTD PMID:20562220 NCBI chr 4:148,218,686...148,234,595
Ensembl chr 4:148,217,395...148,234,595 		JBrowse link
G Fadd Fas associated via death domain multiple interactions
affects response to substance 		ISO Celecoxib promotes the reaction [FAS protein binds to FADD protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP3 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP8 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of PARP1 protein]
FADD affects the susceptibility to Celecoxib 		CTD PMID:15197583 PMID:15572759 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression 		ISO Celecoxib promotes the reaction [FAS protein binds to FADD protein]
Celecoxib results in increased expression of FAS mRNA; Celecoxib results in increased expression of FAS protein 		CTD PMID:15197583 PMID:19141979 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions EXP Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of FASLG mRNA] CTD PMID:24932515 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fasn fatty acid synthase decreases activity
multiple interactions 		ISO Celecoxib results in decreased activity of FASN protein
Dinoprostone promotes the reaction [Celecoxib results in decreased activity of FASN protein] 		CTD PMID:19159447 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression
multiple interactions
decreases expression 		EXP
ISO 		Celecoxib affects the expression of FOS protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of FOS protein]
Celecoxib results in decreased expression of FOS protein 		CTD PMID:18988310 PMID:19463908 PMID:32416088 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of FSHB protein] CTD PMID:24932515 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions 		ISO Celecoxib results in increased expression of GDF15; Celecoxib results in increased expression of GDF15 mRNA
[Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA; GSK3B mutant form inhibits the reaction [Celecoxib results in increased expression of GDF15]; PTGS2 protein affects the reaction [Celecoxib results in increased expression of GDF15 mRNA]; SB 216763 inhibits the reaction [Celecoxib results in increased expression of GDF15] 		CTD PMID:17257745 PMID:17959037 PMID:18089846 PMID:20067113 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Gorasp2 golgi reassembly stacking protein 2 affects expression ISO Celecoxib affects the expression of GORASP2 mRNA CTD PMID:20562220 NCBI chr 3:75,882,607...75,911,322
Ensembl chr 3:75,882,515...75,911,328 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Celecoxib promotes the reaction [Acetaminophen results in increased expression of GPT protein]; PTGES2 protein affects the reaction [Celecoxib promotes the reaction [Acetaminophen results in increased expression of GPT protein]] CTD PMID:31444509 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Celecoxib results in increased expression of GPX1 protein CTD PMID:20883674 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA1 mRNA] CTD PMID:21589914 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA2 mRNA] CTD PMID:21589914 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:168,247,496...168,367,616 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA3 mRNA] CTD PMID:21589914 NCBI chr  X:125,103,975...125,369,690
Ensembl chr  X:125,103,782...125,369,679 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIA4 mRNA] CTD PMID:21589914 NCBI chr 8:9,845,421...10,320,021
Ensembl chr 8:9,847,052...10,319,881 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK1 mRNA] CTD PMID:21589914 NCBI chr11:40,655,974...41,056,966
Ensembl chr11:40,655,975...41,056,517 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 multiple interactions ISO [Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK2 mRNA CTD PMID:21589914 NCBI chr20:53,717,564...54,415,283
Ensembl chr20:53,716,090...54,415,202 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 multiple interactions ISO [Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK3 mRNA CTD PMID:21589914 NCBI chr 5:143,052,442...143,268,873
Ensembl chr 5:143,052,442...143,268,873 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 multiple interactions ISO [Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK4 mRNA CTD PMID:21589914 NCBI chr 8:51,802,045...52,228,751
Ensembl chr 8:51,802,058...52,102,063 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIK5 mRNA] CTD PMID:21589914 NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN1 mRNA] CTD PMID:21589914 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2A mRNA] CTD PMID:21589914 NCBI chr10:6,136,458...6,560,003
Ensembl chr10:6,138,037...6,551,378 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2B mRNA] CTD PMID:21589914 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2C mRNA] CTD PMID:21589914 NCBI chr10:100,987,410...101,006,064
Ensembl chr10:100,987,513...101,005,409 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN2D mRNA] CTD PMID:21589914 NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:105,444,813...105,481,236 		JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3A mRNA] CTD PMID:21589914 NCBI chr 5:68,802,333...69,001,880
Ensembl chr 5:68,804,970...69,001,558 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B multiple interactions ISO Celecoxib promotes the reaction [Kainic Acid results in decreased expression of GRIN3B mRNA] CTD PMID:21589914 NCBI chr 7:10,381,495...10,387,817
Ensembl chr 7:10,381,496...10,387,817 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
multiple interactions 		ISO Celecoxib results in decreased phosphorylation of GSK3B protein
GSK3B mutant form inhibits the reaction [Celecoxib results in increased expression of GDF15] 		CTD PMID:17257745 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gss glutathione synthetase affects expression ISO Celecoxib affects the expression of GSS mRNA CTD PMID:20562220 NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions 		ISO Celecoxib results in increased expression of GSTP1 mRNA
PTGS2 protein affects the reaction [Celecoxib results in increased expression of GSTP1 mRNA] 		CTD PMID:18089846 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Celecoxib inhibits the reaction [Nickel results in increased expression of HK2 mRNA] CTD PMID:27452194 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO
EXP 		Celecoxib results in increased expression of HMOX1 protein CTD PMID:19356721 PMID:23942037 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase multiple interactions ISO [Celecoxib co-treated with NAD] binds to HPGD protein CTD PMID:25526675 NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Celecoxib results in increased expression of HSPA5 CTD PMID:21567098 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression 		ISO Celecoxib inhibits the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]; Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]
Celecoxib results in increased expression of ICAM1 mRNA; Celecoxib results in increased expression of ICAM1 protein 		CTD PMID:14762100 PMID:26513172 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IFNG protein] CTD PMID:32416088 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP 		Celecoxib inhibits the reaction [Dihematoporphyrin Ether results in decreased expression of IL10 protein]
Celecoxib inhibits the reaction [Freund's Adjuvant results in decreased expression of IL10 protein] 		CTD PMID:16230411 PMID:24932515 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL17A protein] CTD PMID:32416088 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
affects secretion 		ISO
EXP 		Celecoxib inhibits the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]; Celecoxib inhibits the reaction [IL1B protein results in increased expression of and results in increased secretion of NRG1 protein]; Celecoxib inhibits the reaction [IL1B protein results in increased expression of NRG1 mRNA]; Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]; Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]]; Celecoxib promotes the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]]; Celecoxib promotes the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]]; Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [IL1B protein results in increased expression of NRG1 mRNA]]
Celecoxib affects the secretion of IL1B protein
[Celecoxib co-treated with Hydrochloric Acid] results in increased expression of IL1B protein; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]
Celecoxib inhibits the reaction [Cisplatin results in increased expression of IL1B protein]; Celecoxib inhibits the reaction [Dihematoporphyrin Ether results in increased expression of IL1B protein] 		CTD PMID:14762100 PMID:15309881 PMID:16230411 PMID:16357062 PMID:19129380 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP Celecoxib inhibits the reaction [BQ 788 results in increased expression of IL2 protein]; Celecoxib inhibits the reaction [Cyclosporine results in increased expression of IL2 protein] CTD PMID:24462674 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with Celecoxib] results in decreased expression of IL6; Celecoxib inhibits the reaction [Mustard Gas results in increased secretion of IL6 protein]
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of IL6 protein]; Celecoxib inhibits the reaction [IL6 protein results in increased secretion of and results in increased abundance of Dinoprostone]; Celecoxib inhibits the reaction [lead acetate results in increased secretion of IL6 protein] 		CTD PMID:16702388 PMID:24285838 PMID:24530660 PMID:31048000 PMID:32416088 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP Celecoxib inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of INS1] CTD PMID:19247274 PMID:20039930 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Atorvastatin co-treated with Celecoxib] results in increased expression of JUN protein; Celecoxib promotes the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of JUN protein]
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of JUN protein] 		CTD PMID:18172863 PMID:32416088 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Lct lactase increases activity EXP Celecoxib results in increased activity of LCT protein CTD PMID:18604318 NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Celecoxib inhibits the reaction [Nickel results in increased expression of LDHA mRNA] CTD PMID:27452194 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of LHB protein] CTD PMID:24932515 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP3 protein]; MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP8 protein]; MAP1LC3B mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP9 protein] CTD PMID:20104024 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases phosphorylation ISO Celecoxib results in decreased phosphorylation of MAP2K1 protein CTD PMID:16123214 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases phosphorylation ISO Celecoxib results in decreased phosphorylation of MAP2K2 protein CTD PMID:16123214 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAP2K4 protein] CTD PMID:32416088 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
decreases phosphorylation 		ISO
EXP 		Celecoxib analog results in increased phosphorylation of MAPK1 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK1 protein]
Celecoxib inhibits the reaction [Acetic Acid results in increased activity of MAPK1]; Celecoxib inhibits the reaction [Pilocarpine results in increased phosphorylation of MAPK1 protein]
Celecoxib analog results in decreased phosphorylation of MAPK1 protein; Celecoxib results in decreased phosphorylation of MAPK1 protein
[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK1 protein 		CTD PMID:11891194 PMID:12464646 PMID:15499625 PMID:16463383 PMID:18988310 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO [epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein CTD PMID:16463383 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
decreases phosphorylation 		ISO
EXP 		Celecoxib analog results in increased phosphorylation of MAPK3 protein
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK3 protein]
Celecoxib inhibits the reaction [Pilocarpine results in increased phosphorylation of MAPK3 protein]
[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK3 protein
Celecoxib analog results in decreased phosphorylation of MAPK3 protein; Celecoxib results in decreased phosphorylation of MAPK3 protein 		CTD PMID:15499625 PMID:16463383 PMID:18988310 PMID:19682443 PMID:32416088 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Celecoxib inhibits the reaction [glycine-extended gastrin 17 results in increased phosphorylation of MAPK8 protein]
Celecoxib inhibits the reaction [deoxynivalenol results in increased phosphorylation of MAPK8 protein] 		CTD PMID:16442704 PMID:32416088 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Celecoxib results in decreased expression of MCL1 protein CTD PMID:14654083 PMID:17952603 PMID:19665451 PMID:20836993 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions EXP Celecoxib inhibits the reaction [Acetic Acid results in increased expression of MET mRNA]; Celecoxib inhibits the reaction [Acetic Acid results in increased expression of MET protein] CTD PMID:11891194 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions
increases expression 		ISO [Celecoxib co-treated with Paraquat] results in increased expression of MITF mRNA; [Oxidopamine co-treated with Celecoxib] results in increased expression of MITF mRNA; Celecoxib inhibits the reaction [Paraquat results in increased expression of MITF mRNA]; Oxidopamine promotes the reaction [Celecoxib results in increased expression of MITF mRNA] CTD PMID:33160981 NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression
multiple interactions 		ISO Celecoxib results in decreased expression of MKI67
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of MKI67 protein]
[FEC protocol co-treated with Celecoxib] results in decreased expression of MKI67 protein 		CTD PMID:16507397 PMID:20697803 PMID:32416088 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
affects expression 		ISO
EXP 		Celecoxib promotes the reaction [arsenic trioxide results in decreased expression of MMP2 mRNA]; Celecoxib promotes the reaction [arsenic trioxide results in decreased expression of MMP2 protein]
Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of MMP2 mRNA]
Celecoxib affects the expression of MMP2 mRNA 		CTD PMID:16420518 PMID:18438340 PMID:21540248 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO
EXP 		Celecoxib inhibits the reaction [Dihematoporphyrin Ether results in increased expression of MMP9 protein]
Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of MMP9 mRNA] 		CTD PMID:16230411 PMID:16420518 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity 		EXP Celecoxib inhibits the reaction [Freund's Adjuvant results in increased activity of MPO protein]; Celecoxib inhibits the reaction [Gentamicins results in increased expression of MPO protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
Celecoxib results in increased activity of MPO protein 		CTD PMID:15309881 PMID:21893697 PMID:24932515 PMID:31628940 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrps26 mitochondrial ribosomal protein S26 affects expression ISO Celecoxib affects the expression of MRPS26 mRNA CTD PMID:20562220 NCBI chr 3:138,222,324...138,223,987
Ensembl chr 3:138,222,165...138,223,987 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 affects expression ISO Celecoxib affects the expression of MTUS1 mRNA CTD PMID:20562220 NCBI chr16:57,905,991...58,051,466
Ensembl chr16:57,906,128...58,051,474 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression ISO Celecoxib results in decreased expression of MVD CTD PMID:17224647 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Celecoxib analog results in decreased expression of MYC protein; Celecoxib results in decreased expression of MYC protein CTD PMID:19682443 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Celecoxib inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Celecoxib inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] CTD PMID:15489888 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Celecoxib inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] CTD PMID:15489888 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Ngf nerve growth factor affects expression EXP Celecoxib affects the expression of NGF mRNA CTD PMID:19129380 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO Celecoxib results in increased expression of NGFR mRNA; Celecoxib results in increased expression of NGFR protein CTD PMID:17447067 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP
ISO 		Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of NOS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of NOS2 protein] 		CTD PMID:21893697 PMID:24932515 PMID:32416088 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP Celecoxib inhibits the reaction [Lead results in increased expression of NOX1 mRNA]; Celecoxib inhibits the reaction [Mercuric Chloride results in increased expression of NOX1 mRNA] CTD PMID:23415682 PMID:25596430 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 mRNA] CTD PMID:19194550 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP Celecoxib affects the localization of and results in increased activity of NR3C1 protein CTD PMID:15700047 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO Celecoxib inhibits the reaction [IL1B protein results in increased expression of and results in increased secretion of NRG1 protein]; Celecoxib inhibits the reaction [IL1B protein results in increased expression of NRG1 mRNA]; Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [IL1B protein results in increased expression of NRG1 mRNA]] CTD PMID:16357062 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Oxa1l OXA1L, mitochondrial inner membrane protein affects expression ISO Celecoxib affects the expression of OXA1L mRNA CTD PMID:20562220 NCBI chr15:31,783,725...31,791,353
Ensembl chr15:31,776,063...31,792,354 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases activity
affects cleavage 		ISO [Atorvastatin co-treated with Celecoxib] results in increased cleavage of PARP1 protein; Celecoxib inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]; Celecoxib promotes the reaction [Docetaxel results in increased cleavage of and results in increased expression of PARP1 protein]; Celecoxib promotes the reaction [tetracycline CMT-3 results in increased cleavage of and results in increased expression of PARP1 protein]; Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein; Docetaxel promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]; FADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of PARP1 protein]; tetracycline CMT-3 promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]; TNFRSF10B mutant form inhibits the reaction [Celecoxib results in increased cleavage of PARP1 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of PARP1 protein]
Celecoxib promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein]
Celecoxib results in increased activity of PARP1 protein
Celecoxib analog affects the cleavage of PARP1 protein 		CTD PMID:12824303 PMID:15572759 PMID:15688368 PMID:15911099 PMID:16123214 More... NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Celecoxib results in decreased expression of PCNA protein CTD PMID:15570007 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO
EXP 		Celecoxib inhibits the reaction [PDGFA results in increased abundance of Dinoprostone]; Celecoxib inhibits the reaction [PDGFA results in increased abundance of Epoprostenol]; Celecoxib inhibits the reaction [PDGFA results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19201774 NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 decreases activity
multiple interactions 		ISO Celecoxib analog results in decreased activity of PDPK1 protein; Celecoxib results in decreased activity of PDPK1 protein
[Atorvastatin co-treated with Celecoxib] results in decreased phosphorylation of and results in decreased expression of PDPK1 protein 		CTD PMID:12000750 PMID:15499625 PMID:18172863 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Pdpn podoplanin decreases expression ISO Celecoxib results in decreased expression of PDPN mRNA CTD PMID:17285134 NCBI chr 5:160,884,995...160,919,112
Ensembl chr 5:160,884,993...160,925,637 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP3 protein]; PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP8 protein]; PIK3C3 mutant form promotes the reaction [[Celecoxib co-treated with ABT-737] results in increased cleavage of CASP9 protein] CTD PMID:20104024 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539 		JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions ISO [Celecoxib co-treated with docetaxel] results in decreased expression of PLA2G4A protein; Celecoxib inhibits the reaction [PLA2G4A gene mutant form results in decreased expression of SOD1 protein] CTD PMID:15816863 PMID:16052515 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Plin2 perilipin 2 increases expression ISO Celecoxib results in increased expression of PLIN2 mRNA CTD PMID:19415698 NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases response to substance ISO PMAIP1 results in increased susceptibility to Celecoxib CTD PMID:19665451 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Poglut2 protein O-glucosyltransferase 2 affects expression ISO Celecoxib affects the expression of POGLUT2 mRNA CTD PMID:20562220 NCBI chr 9:53,748,484...53,801,453
Ensembl chr 9:53,740,998...53,760,588 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Celecoxib inhibits the reaction [docetaxel results in increased expression of POMC mRNA] CTD PMID:22902858 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO Celecoxib results in increased expression of PPARA mRNA; Celecoxib results in increased expression of PPARA protein CTD PMID:19415698 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Celecoxib analog results in decreased expression of PPARD protein; Celecoxib results in decreased expression of PPARD protein CTD PMID:19682443 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression
affects localization 		ISO
EXP 		2-chloro-5-nitrobenzanilide inhibits the reaction [Celecoxib affects the localization of PPARG protein]; [Celecoxib results in decreased activity of and results in decreased expression of PTGS2 protein] which results in increased expression of PPARG; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Celecoxib affects the localization of PPARG protein]
[Celecoxib co-treated with docetaxel] results in increased expression of PPARG protein
Celecoxib inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]
Celecoxib results in increased expression of PPARG mRNA; Celecoxib results in increased expression of PPARG protein 		CTD PMID:16052515 PMID:19247274 PMID:19522023 PMID:23943857 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO Celecoxib promotes the reaction [Quercetin results in increased phosphorylation of and results in increased activity of PRKAA1 protein] CTD PMID:19293639 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCA protein] CTD PMID:32416088 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCE protein] CTD PMID:32416088 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO Celecoxib inhibits the reaction [deoxynivalenol affects the localization of PRKCG protein] CTD PMID:32416088 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Ptgds prostaglandin D2 synthase increases expression ISO Celecoxib results in increased expression of PTGDS protein CTD PMID:23943857 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978 		JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions ISO Celecoxib inhibits the reaction [PTGER1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene] CTD PMID:21739481 NCBI chr19:41,374,983...41,379,593
Ensembl chr19:41,374,471...41,378,284 		JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions EXP Celecoxib inhibits the reaction [Heymann Nephritis Antigenic Complex results in increased expression of PTGER3 mRNA] CTD PMID:14636300 NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:249,264,985...249,409,846 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP [Celecoxib co-treated with Heymann Nephritis Antigenic Complex] affects the expression of PTGER4 mRNA CTD PMID:14636300 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions
decreases expression 		ISO
EXP 		[Celecoxib co-treated with docetaxel] results in decreased expression of PTGES protein
Celecoxib results in decreased expression of PTGES mRNA 		CTD PMID:16052515 PMID:16273290 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995 		JBrowse link
G Ptges2 prostaglandin E synthase 2 multiple interactions ISO PTGES2 protein affects the reaction [Celecoxib promotes the reaction [Acetaminophen results in increased expression of GPT protein]] CTD PMID:31444509 NCBI chr 3:36,088,246...36,095,430
Ensembl chr 3:36,088,246...36,097,694 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity
decreases expression 		ISO
EXP 		Celecoxib analog results in decreased activity of PTGS1 protein; Celecoxib results in decreased activity of PTGS1 protein
Celecoxib results in decreased expression of PTGS1 mRNA alternative form 		CTD PMID:11375891 PMID:16141368 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
affects binding
decreases activity
multiple interactions
increases response to substance
increases expression 		ISO
EXP 		Celecoxib analog results in decreased expression of PTGS2 protein; Celecoxib results in decreased expression of PTGS2; Celecoxib results in decreased expression of PTGS2 mRNA; Celecoxib results in decreased expression of PTGS2 protein
Celecoxib binds to PTGS2 protein
Celecoxib results in decreased activity of PTGS2 protein
[Celecoxib co-treated with sulindac sulfone] results in decreased expression of PTGS2 protein; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; Celecoxib inhibits the reaction [BQ 788 results in decreased expression of PTGS2 protein]; Celecoxib inhibits the reaction [Cyclosporine results in decreased expression of PTGS2 protein]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of PTGS2 mRNA]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of PTGS2]; Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [Gentamicins results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [PTGS2 protein affects the abundance of lipoxin A4]; Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of PTGS2 mRNA]; Celecoxib promotes the reaction [sulindac sulfone results in decreased expression of PTGS2 protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]
Celecoxib results in decreased activity of PTGS2 protein; Celecoxib results in decreased activity of PTGS2 protein alternative form
[Celecoxib results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprost; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprostone; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased abundance of Thromboxane A2; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of BIRC5 protein; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 mRNA; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of COL10A1 protein; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Mustard Gas; [Celecoxib results in decreased activity of PTGS2 protein] which results in increased susceptibility to Acetaminophen; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; Celecoxib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [potassium superoxide results in increased expression of PTGS2 mRNA]; Celecoxib results in decreased susceptibility to [Lipopolysaccharides results in increased expression of PTGS2 protein]
PTGS2 results in increased susceptibility to Celecoxib
Celecoxib results in increased expression of PTGS2 mRNA; Celecoxib results in increased expression of PTGS2 protein
Celecoxib analog results in decreased activity of PTGS2 protein; Celecoxib results in decreased activity of PTGS2 protein; Celecoxib results in decreased activity of PTGS2 protein mutant form
[Celecoxib analog results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprostone; [Celecoxib results in decreased activity of and results in decreased expression of PTGS2 protein] which results in increased expression of PPARG; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased abundance of Dinoprostone; [FEC protocol co-treated with Celecoxib] results in decreased expression of PTGS2 protein; [tetraarsenic tetrasulfide co-treated with Celecoxib] results in decreased expression of PTGS2 protein; Celecoxib binds to and results in decreased activity of PTGS2 protein; Celecoxib inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 mRNA]; Celecoxib inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; Celecoxib inhibits the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]; Celecoxib inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Celecoxib promotes the reaction [Arsenic Trioxide results in decreased expression of PTGS2 protein]; Celecoxib promotes the reaction [Quercetin results in decreased expression of PTGS2 protein]; Celecoxib results in decreased activity of and results in decreased expression of PTGS2 protein; Celecoxib results in increased expression of and results in increased activity of PTGS2 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Celecoxib results in increased activity of PTGS2 protein]; PTGS2 protein affects the reaction [Celecoxib results in increased expression of DES mRNA]; PTGS2 protein affects the reaction [Celecoxib results in increased expression of GDF15 mRNA]; PTGS2 protein affects the reaction [Celecoxib results in increased expression of GSTP1 mRNA] 		CTD PMID:11743745 PMID:12417326 PMID:12727271 PMID:12888902 PMID:12967936 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pxk PX domain containing serine/threonine kinase like affects expression ISO Celecoxib affects the expression of PXK mRNA CTD PMID:20562220 NCBI chr15:19,190,085...19,258,711
Ensembl chr15:19,190,085...19,258,671 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases expression 		ISO [Atorvastatin co-treated with Celecoxib] results in decreased expression of RB1 protein modified form; [Atorvastatin co-treated with Celecoxib] results in increased expression of RB1 protein
Celecoxib results in increased expression of RB1 		CTD PMID:18172863 PMID:19846907 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression 		ISO
EXP 		[irinotecan co-treated with Thalidomide co-treated with Celecoxib] results in increased expression of RELA protein; Celecoxib inhibits the reaction [Doxorubicin affects the localization of RELA protein]; Celecoxib inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Celecoxib inhibits the reaction [TNF protein results in increased activity of RELA protein]
Celecoxib inhibits the reaction [Gentamicins results in increased expression of RELA protein]
Celecoxib results in decreased expression of RELA protein 		CTD PMID:15489888 PMID:15570007 PMID:16685529 PMID:17097285 PMID:19635192 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin decreases expression EXP Celecoxib results in decreased expression of REN protein CTD PMID:10742298 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Rhoa ras homolog family member A multiple interactions ISO Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOA protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOA protein] CTD PMID:18172863 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [Atorvastatin co-treated with Celecoxib] results in increased localization of RHOB protein; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOB protein] CTD PMID:18172863 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rhoc ras homolog family member C multiple interactions ISO Celecoxib promotes the reaction [Atorvastatin results in decreased localization of RHOC protein]; Celecoxib promotes the reaction [Atorvastatin results in increased expression of RHOC protein] CTD PMID:18172863 NCBI chr 2:194,975,586...194,981,637
Ensembl chr 2:194,975,242...194,983,745 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects expression ISO Celecoxib affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 mRNA; [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased expression of RUNX2 protein CTD PMID:27050768 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Saraf store-operated calcium entry-associated regulatory factor affects expression ISO Celecoxib affects the expression of SARAF mRNA CTD PMID:20562220 NCBI chr16:64,720,404...64,738,653
Ensembl chr16:64,720,418...64,738,653 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component affects expression ISO Celecoxib affects the expression of SEC23A mRNA CTD PMID:20562220 NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904 		JBrowse link
G Sele selectin E multiple interactions ISO Celecoxib inhibits the reaction [nitroaspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of SELE protein]] CTD PMID:14762100 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions EXP Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of SERPINH1 mRNA] CTD PMID:16420518 NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976 		JBrowse link
G Si sucrase-isomaltase increases activity EXP Celecoxib results in increased activity of SI protein CTD PMID:18604318 NCBI chr 2:159,804,568...159,884,902
Ensembl chr 2:159,804,568...159,883,934 		JBrowse link
G Slc16a3 solute carrier family 16 member 3 multiple interactions ISO Celecoxib inhibits the reaction [Nickel results in increased expression of SLC16A3 mRNA] CTD PMID:27452194 NCBI chr10:106,712,328...106,756,168
Ensembl chr10:106,714,466...106,720,903 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
increases expression 		ISO Celecoxib inhibits the reaction [Nickel results in increased expression of SLC2A1 mRNA]
Celecoxib results in increased expression of SLC2A1 mRNA 		CTD PMID:19327236 PMID:27452194 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions
decreases expression
affects expression 		ISO [Celecoxib results in decreased expression of SLC31A1 protein] which results in decreased import of and results in decreased susceptibility to Cisplatin
Celecoxib affects the expression of SLC31A1 mRNA 		CTD PMID:20562220 PMID:21177414 NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:80,830,389...80,859,809 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Celecoxib results in increased expression of SLC3A2 mRNA CTD PMID:33785417 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Celecoxib results in increased expression of SLC7A11 mRNA CTD PMID:33785417 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases activity ISO Celecoxib results in decreased activity of SLCO1B3 protein CTD PMID:39023798 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
G Snai1 snail family transcriptional repressor 1 affects localization
multiple interactions 		ISO Celecoxib affects the localization of SNAI1 protein
Celecoxib inhibits the reaction [SNAI1 protein binds to CDH1 promoter] 		CTD PMID:29932878 NCBI chr 3:176,667,476...176,671,965 JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO Celecoxib inhibits the reaction [PLA2G4A gene mutant form results in decreased expression of SOD1 protein] CTD PMID:15816863 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Celecoxib results in decreased expression of SOD2 protein CTD PMID:18848576 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sox2 SRY-box transcription factor 2 multiple interactions ISO Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]; Dinoprostone inhibits the reaction [Celecoxib inhibits the reaction [Arsenic Trioxide results in increased expression of SOX2 protein]] CTD PMID:29396848 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP Celecoxib inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein] CTD PMID:19356721 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Celecoxib co-treated with ABT-737] results in decreased expression of SQSTM1 protein CTD PMID:20104024 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Sstr2 somatostatin receptor 2 increases expression ISO Celecoxib results in increased expression of SSTR2 protein CTD PMID:17959037 NCBI chr10:99,163,353...99,170,519
Ensembl chr10:99,162,740...99,183,863 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP Celecoxib inhibits the reaction [Freund's Adjuvant results in decreased expression of STAR mRNA] CTD PMID:24932515 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Celecoxib results in decreased activity of PTGS2 protein] which results in decreased phosphorylation of STAT3 protein CTD PMID:21268125 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO Celecoxib inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
affects activity 		ISO Celecoxib affects the reaction [[Phosphoadenosine Phosphosulfate co-treated with SULT2A1 protein] affects the sulfation of Ethinyl Estradiol]
Celecoxib affects the activity of SULT2A1 protein 		CTD PMID:15483193 PMID:17239972 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Tfeb transcription factor EB increases expression
multiple interactions 		ISO Celecoxib results in increased expression of TFEB mRNA
[Celecoxib co-treated with Paraquat] results in increased expression of TFEB mRNA; [Oxidopamine co-treated with Celecoxib] results in increased expression of TFEB mRNA; Celecoxib inhibits the reaction [Paraquat results in increased expression of TFEB mRNA]; Oxidopamine promotes the reaction [Celecoxib results in increased expression of TFEB mRNA] 		CTD PMID:33160981 NCBI chr 9:20,696,440...20,752,265
Ensembl chr 9:20,696,441...20,727,863 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions EXP Celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of TGFA protein] CTD PMID:15309881 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression 		EXP Celecoxib inhibits the reaction [Cyclosporine results in increased expression of TGFB1 protein]; Celecoxib inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA]
Celecoxib results in decreased expression of TGFB1 mRNA 		CTD PMID:19194550 PMID:19201774 PMID:24462674 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP [Carbon Tetrachloride co-treated with Celecoxib] results in increased expression of TIMP2 mRNA CTD PMID:16420518 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tm9sf4 transmembrane 9 superfamily member 4 affects expression ISO Celecoxib affects the expression of TM9SF4 mRNA CTD PMID:20562220 NCBI chr 3:162,086,758...162,135,620
Ensembl chr 3:162,087,347...162,151,721 		JBrowse link
G Tmem131 transmembrane protein 131 affects expression ISO Celecoxib affects the expression of TMEM131 mRNA CTD PMID:20562220 NCBI chr 9:46,512,328...46,658,624
Ensembl chr 9:46,512,328...46,658,481 		JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 affects expression ISO Celecoxib affects the expression of TMX2 mRNA CTD PMID:20562220 NCBI chr 3:90,161,628...90,169,278
Ensembl chr 3:90,160,930...90,169,278 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression 		ISO
EXP 		[Polyphenols co-treated with Antioxidants co-treated with Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Medroxyprogesterone Acetate co-treated with Celecoxib] results in decreased expression of TNF; Celecoxib inhibits the reaction [Mustard Gas results in increased secretion of TNF protein]; Celecoxib inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Celecoxib inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Celecoxib inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Celecoxib inhibits the reaction [TNF protein results in increased activity of RELA protein]; Celecoxib inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Celecoxib inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Celecoxib inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
Celecoxib results in decreased expression of TNF protein
Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]; Celecoxib inhibits the reaction [Dietary Fats results in increased expression of TNF protein]; Celecoxib inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]; Celecoxib inhibits the reaction [Gentamicins results in increased expression of TNF protein]; Celecoxib promotes the reaction [sulindac sulfone results in decreased expression of TNF protein]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]
Celecoxib inhibits the reaction [Cisplatin results in increased expression of TNF protein]; Celecoxib inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]; Celecoxib inhibits the reaction [Dihematoporphyrin Ether results in increased expression of TNF protein]; Celecoxib inhibits the reaction [lead acetate results in increased secretion of TNF protein] 		CTD PMID:15489888 PMID:16230411 PMID:16702388 PMID:17908994 PMID:19247274 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO Celecoxib results in increased expression of TNFRSF10A mRNA; Celecoxib results in increased expression of TNFRSF10A protein CTD PMID:15572759 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B decreases secretion
increases expression 		ISO Celecoxib results in decreased secretion of TNFRSF11B protein
Celecoxib results in increased expression of TNFRSF11B mRNA 		CTD PMID:19327236 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP3 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP6 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP7 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP8 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of and results in increased activity of CASP9 protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of BID protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of DFFA protein]; TNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of PARP1 protein] CTD PMID:15572759 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
increases response to substance 		ISO
EXP 		Celecoxib results in increased expression of TP53 mRNA; Celecoxib results in increased expression of TP53 protein
Celecoxib inhibits the reaction [Gentamicins results in increased expression of TP53 protein]
[Celecoxib co-treated with docetaxel] results in increased expression of TRP53 protein; Celecoxib promotes the reaction [Doxorubicin results in increased expression of TRP53 protein]
TP53 results in increased susceptibility to Celecoxib
[FEC protocol co-treated with Celecoxib] results in decreased expression of TP53 protein; Celecoxib results in increased activity of and results in increased localization of TP53 protein; Celecoxib results in increased expression of and results in increased phosphorylation of TP53 protein; pifithrin inhibits the reaction [Celecoxib results in increased expression of TP53 protein]; pifithrin inhibits the reaction [TP53 results in increased susceptibility to Celecoxib]; TP53 affects the reaction [Celecoxib results in increased expression of CDKN1A mRNA]; TP53 protein promotes the reaction [Celecoxib results in increased expression of BBC3 protein] 		CTD PMID:15458769 PMID:16052515 PMID:16507397 PMID:18202791 PMID:18760266 More... NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Celecoxib results in decreased activity of UGT2B7 protein CTD PMID:39023798 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
G Vapb VAMP associated protein B and C affects expression ISO Celecoxib affects the expression of VAPB mRNA CTD PMID:20562220 NCBI chr 3:182,954,247...182,997,018
Ensembl chr 3:182,954,240...183,028,619 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
affects expression
increases expression 		ISO
EXP 		Celecoxib results in decreased expression of VEGFA; Celecoxib results in decreased expression of VEGFA protein
Celecoxib results in decreased expression of VEGFA mRNA; Celecoxib results in decreased expression of VEGFA protein
Ampicillin inhibits the reaction [Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Celecoxib promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
[Celecoxib co-treated with docetaxel] results in decreased expression of VEGFA protein; Celecoxib inhibits the reaction [Dihematoporphyrin Ether results in increased expression of VEGFA protein]
Celecoxib affects the expression of VEGFA mRNA
Celecoxib results in increased expression of VEGFA mRNA; Celecoxib results in increased expression of VEGFA protein 		CTD PMID:15126378 PMID:16052515 PMID:16230411 PMID:17201140 PMID:17224647 More... NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
chlorpropamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to Chlorpropamide CTD PMID:22209866 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Chlorpropamide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Avp arginine vasopressin decreases secretion ISO Chlorpropamide results in decreased secretion of AVP protein modified form CTD PMID:5029389 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Chlorpropamide results in increased expression of FOS mRNA CTD PMID:12730611 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Ins2 insulin 2 decreases expression
increases expression
multiple interactions 		ISO Chlorpropamide results in decreased expression of INS protein
Chlorpropamide results in increased expression of INS mRNA
Chlorpropamide inhibits the reaction [Glucose results in decreased secretion of INS protein] 		CTD PMID:15642492 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to Chlorpropamide CTD PMID:22209866 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
chlorthalidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 decreases expression EXP Chlorthalidone results in decreased expression of FGFR3 mRNA CTD PMID:20625077 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:81,211,800...81,227,209 		JBrowse link
G Nrp2 neuropilin 2 decreases expression EXP Chlorthalidone results in decreased expression of NRP2 mRNA CTD PMID:20625077 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871 		JBrowse link
G Ren renin increases expression
increases activity 		ISO Chlorthalidone results in increased expression of REN protein modified form
Chlorthalidone results in increased activity of REN protein 		CTD PMID:796642 PMID:1116335 PMID:3319646 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression EXP Chlorthalidone results in decreased expression of TGFB3 mRNA CTD PMID:20625077 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Vegfc vascular endothelial growth factor C decreases expression
increases expression 		EXP Chlorthalidone results in decreased expression of VEGFC mRNA; Chlorthalidone results in decreased expression of VEGFC protein
Chlorthalidone results in increased expression of VEGFC protein 		CTD PMID:20625077 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
co-trimoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 increases secretion ISO Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form CTD PMID:14714756 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
cyazofamid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions 		ISO ABCB1 protein results in increased transport of cyazofamid
cyazofamid affects the reaction [ABCB1 protein results in increased uptake of Digoxin]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of cyazofamid] 		CTD PMID:32003934 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases uptake ISO ABCC2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases uptake ISO ABCG2 protein results in increased uptake of cyazofamid CTD PMID:32003934 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO cyazofamid results in decreased expression of CYP3A5 mRNA CTD PMID:34642769 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO cyazofamid results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Esrra estrogen related receptor, alpha increases activity ISO cyazofamid results in increased activity of ESRRA protein CTD PMID:20143881 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:32003934 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO cyazofamid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO cyazofamid inhibits the reaction [SLCO1B3 protein results in increased uptake of estrone sulfate] CTD PMID:32003934 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
dabrafenib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO dabrafenib results in increased expression of ABCC1 mRNA CTD PMID:34780725 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO dabrafenib results in increased expression of ABCG2 mRNA CTD PMID:34780725 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase multiple interactions
affects response to substance
increases response to substance
decreases activity 		ISO [BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein; betulin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]; CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; fatostatin affects the reaction [BRAF protein affects the susceptibility to [dabrafenib co-treated with trametinib]]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]
dabrafenib results in decreased activity of BRAF protein; dabrafenib results in decreased activity of BRAF protein mutant form 		CTD PMID:20823850 PMID:23237741 PMID:26978007 PMID:29950559 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO CCND1 protein inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib] CTD PMID:26978007 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO dabrafenib results in decreased activity of CYP1A2 protein CTD PMID:34780725 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO dabrafenib results in decreased activity of CYP2C19 protein CTD PMID:34780725 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO dabrafenib results in decreased activity of CYP2C8 protein CTD PMID:34780725
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
decreases activity 		ISO dabrafenib results in increased expression of CYP3A4 mRNA
dabrafenib inhibits the reaction [CYP3A4 protein results in decreased susceptibility to Docetaxel]
dabrafenib results in decreased activity of CYP3A4 protein 		CTD PMID:34780725 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO dabrafenib results in decreased activity of CYP3A5 protein CTD PMID:34780725 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO dabrafenib inhibits the reaction [decabromobiphenyl ether results in increased phosphorylation of EGFR protein] CTD PMID:38641160 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of GPT protein] CTD PMID:27458080 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein] CTD PMID:27458080 PMID:29042256 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased secretion of IL6 protein] CTD PMID:27458080 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] CTD PMID:29042256 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Itgb5 integrin subunit beta 5 multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] CTD PMID:29042256 NCBI chr11:80,333,588...80,449,373
Ensembl chr11:80,333,590...80,449,373 		JBrowse link
G Kras KRAS proto-oncogene, GTPase affects response to substance
multiple interactions 		ISO KRAS protein affects the susceptibility to dabrafenib
[KRAS protein affects the susceptibility to dabrafenib] which affects the expression of TNFRSF10B protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein 		CTD PMID:27222248 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases phosphorylation
multiple interactions 		ISO dabrafenib results in decreased phosphorylation of MAP2K1 protein
decabromobiphenyl ether inhibits the reaction [dabrafenib results in decreased phosphorylation of MAP2K1 protein] 		CTD PMID:38641160 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions
decreases phosphorylation 		ISO decabromobiphenyl ether inhibits the reaction [dabrafenib results in decreased phosphorylation of MAP2K2 protein] CTD PMID:38641160 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation 		ISO [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK1 protein; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK1 protein]; decabromobiphenyl ether inhibits the reaction [dabrafenib results in decreased phosphorylation of MAPK1 protein]; MAPK1 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK1 protein] CTD PMID:26978007 PMID:27222248 PMID:27458080 PMID:31962201 PMID:38641160 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
increases phosphorylation 		ISO [KRAS protein affects the susceptibility to dabrafenib] which affects the phosphorylation of MAPK3 protein; dabrafenib inhibits the reaction [Polyphosphates results in increased phosphorylation of MAPK3 protein]; decabromobiphenyl ether inhibits the reaction [dabrafenib results in decreased phosphorylation of MAPK3 protein]; MAPK3 protein modified form inhibits the reaction [BRAF protein mutant form results in increased susceptibility to dabrafenib]; SRPIN340 inhibits the reaction [dabrafenib results in increased phosphorylation of MAPK3 protein] CTD PMID:26978007 PMID:27222248 PMID:27458080 PMID:31962201 PMID:38641160 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO dabrafenib inhibits the reaction [lenvatinib results in increased cleavage of PARP1 protein] CTD PMID:38754640 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO dabrafenib inhibits the reaction [decabromobiphenyl ether results in increased phosphorylation of RAF1 protein] CTD PMID:38641160 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased activity of RELA protein] CTD PMID:27458080 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Sele selectin E multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein] CTD PMID:27458080 PMID:29042256 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases cleavage
multiple interactions 		ISO dabrafenib results in decreased cleavage of SREBF1 protein
[BRAF protein affects the susceptibility to dabrafenib] which affects the cleavage of SREBF1 protein 		CTD PMID:29950559 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [SRPIN340 co-treated with dabrafenib] results in decreased phosphorylation of SRSF5 protein CTD PMID:31962201 NCBI chr 6:106,333,998...106,341,467
Ensembl chr 6:106,336,756...106,341,931 		JBrowse link
G Tgfbi transforming growth factor, beta induced multiple interactions ISO dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TGFBI mRNA]; dabrafenib inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TGFBI protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of ICAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of SELE protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] CTD PMID:29042256 NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of TNF protein] CTD PMID:27458080 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO dabrafenib inhibits the reaction [lenvatinib results in increased expression of TNFSF10 protein] CTD PMID:38754640 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 mRNA]; dabrafenib inhibits the reaction [Polyphosphates results in increased expression of VCAM1 protein]; dabrafenib inhibits the reaction [TGFBI protein results in increased expression of VCAM1 protein] CTD PMID:27458080 PMID:29042256 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
delavirdine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
diclofenamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 multiple interactions ISO Dichlorphenamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Dichlorphenamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
Diclosulam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO diclosulam results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
dofetilide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions EXP dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B mRNA]; dofetilide inhibits the reaction [Isoproterenol results in decreased expression of FKBP1B protein] CTD PMID:20723002 NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:33,558,517...33,568,129 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity
affects binding 		ISO [Terfenadine co-treated with dofetilide] binds to and results in decreased activity of KCNH2 protein; Acids inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]; dofetilide analog inhibits the reaction [Astemizole binds to KCNH2 protein]; dofetilide analog inhibits the reaction [dofetilide binds to KCNH2 protein]; dofetilide binds to and results in decreased activity of KCNH2 protein; dofetilide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; dofetilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; Hydrogen Peroxide inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein mutant form]; naringenin promotes the reaction [dofetilide results in decreased activity of KCNH2 protein]; Potassium affects the reaction [dofetilide analog inhibits the reaction [dofetilide binds to KCNH2 protein]]; Potassium inhibits the reaction [dofetilide results in decreased activity of KCNH2 protein]; Potassium promotes the reaction [dofetilide binds to KCNH2 protein] CTD PMID:9395068 PMID:10828461 PMID:15272206 PMID:15821840 PMID:15961988 More... NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions EXP dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of NCF2 protein] CTD PMID:20723002 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149 		JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE mRNA]; dofetilide inhibits the reaction [Isoproterenol results in increased expression of PRKCE protein] CTD PMID:20723002 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
dorzolamide hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 multiple interactions ISO dorzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO dorzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
dronedarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator increases expression EXP Dronedarone results in increased expression of BCL2 protein CTD PMID:27197836 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 increases activity ISO dronedarone results in increased activity of CASP3 protein CTD PMID:23135547 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity ISO dronedarone results in increased activity of CASP7 protein CTD PMID:23135547 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO dronedarone results in decreased expression of CCND1 protein CTD PMID:29616291 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO dronedarone results in decreased expression of CCND3 protein CTD PMID:29616291 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO dronedarone results in decreased expression of CDK2 protein CTD PMID:29616291 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO dronedarone results in decreased expression of CDK4 protein CTD PMID:29616291 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 decreases expression ISO dronedarone results in decreased expression of CDK6 protein CTD PMID:29616291 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases activity ISO dronedarone results in decreased activity of CPT1A protein CTD PMID:24881592 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases response to substance
decreases activity
increases metabolic processing
multiple interactions 		ISO CYP1A1 protein results in increased susceptibility to dronedarone
Dronedarone results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased metabolism of dronedarone
[CYP1A1 protein results in increased metabolism of dronedarone] which results in increased abundance of N-desbutyldronedarone 		CTD PMID:29616291 PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Dronedarone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of dronedarone CTD PMID:29616291 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases metabolic processing ISO CYP2C18 protein results in increased metabolism of Dronedarone CTD PMID:29616291 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases metabolic processing ISO CYP2C19 protein results in increased metabolism of dronedarone CTD PMID:29616291 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases response to substance
increases metabolic processing
multiple interactions 		ISO CYP2D6 protein results in decreased susceptibility to dronedarone
CYP2D6 protein results in increased metabolism of dronedarone
[CYP2D6 protein results in increased metabolism of Dronedarone] which results in decreased abundance of N-desbutyldronedarone; CYP2D6 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; CYP2D6 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein] 		CTD PMID:29616291 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of dronedarone CTD PMID:29616291 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases response to substance
increases metabolic processing
multiple interactions 		ISO CYP3A4 protein results in decreased susceptibility to Dronedarone
CYP3A4 protein results in increased metabolism of Dronedarone
[CYP3A4 protein results in increased metabolism of Dronedarone] which results in increased abundance of N-desbutyldronedarone; [CYP3A4 protein results in increased metabolism of Dronedarone] which results in increased chemical synthesis of N-desbutyldronedarone; CYP3A4 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; CYP3A4 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein] 		CTD PMID:29616291 PMID:31756459 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases metabolic processing
decreases response to substance 		ISO [CYP3A5 protein results in increased metabolism of Dronedarone] which results in increased abundance of N-desbutyldronedarone; CYP3A5 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; CYP3A5 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein]
CYP3A5 protein results in increased metabolism of dronedarone
CYP3A5 protein results in decreased susceptibility to dronedarone 		CTD PMID:29616291 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO dronedarone binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO dronedarone binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation 		ISO CYP2D6 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein]; CYP3A4 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein]; CYP3A5 protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein]; TOP2A protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein] CTD PMID:29616291 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions 		ISO dronedarone results in decreased activity of KCNH2 protein
Potassium inhibits the reaction [dronedarone results in decreased activity of KCNH2 protein] 		CTD PMID:15618689 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP dronedarone results in decreased expression of MYH6 mRNA CTD PMID:17535870 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO dronedarone binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 affects response to substance ISO SLC22A5 protein affects the susceptibility to dronedarone CTD PMID:24881592 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO dronedarone results in increased expression of SOD2 mRNA CTD PMID:23135547 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
decreases expression 		ISO
EXP 		dronedarone binds to and results in decreased activity of THRA protein
dronedarone results in decreased expression of THRA mRNA alternative form 		CTD PMID:17535870 PMID:25752796 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP dronedarone results in decreased expression of THRB mRNA alternative form CTD PMID:17535870 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression
multiple interactions 		ISO dronedarone results in decreased expression of TOP2A mRNA; dronedarone results in decreased expression of TOP2A protein
CYP2D6 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; CYP3A4 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; CYP3A5 protein inhibits the reaction [Dronedarone results in decreased expression of TOP2A protein]; TOP2A protein inhibits the reaction [Dronedarone results in increased phosphorylation of H2AX protein] 		CTD PMID:29616291 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
E-4031 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone multiple interactions EXP E 4031 inhibits the reaction [Corticosterone inhibits the reaction [CRH protein results in increased secretion of Adrenocorticotropic Hormone]] CTD PMID:18835572 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases response to substance ISO CYP19A1 gene mutant form results in decreased susceptibility to E 4031 CTD PMID:25972195 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 multiple interactions ISO [KCNE2 protein binds to KCNH2 protein] which results in increased susceptibility to E 4031; E 4031 results in decreased activity of [KCNE2 protein binds to KCNH2 protein] CTD PMID:10219239 NCBI chr11:45,003,468...45,015,942
Ensembl chr11:45,014,406...45,016,168 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 affects binding
multiple interactions 		ISO E 4031 binds to KCNH1 protein
E 4031 binds to and results in decreased activity of KCNH1 protein 		CTD PMID:18471075 PMID:18497958 NCBI chr13:106,253,101...106,555,712
Ensembl chr13:106,253,213...106,555,710 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects localization
multiple interactions
increases activity
decreases activity
affects binding 		ISO
EXP 		E 4031 affects the localization of KCNH2 protein mutant form
E 4031 inhibits the reaction [Progesterone results in decreased localization of KCNH2 protein]
E 4031 results in increased activity of KCNH2 protein mutant form
E 4031 results in decreased activity of KCNH2 protein
[KCNE2 protein binds to KCNH2 protein] which results in increased susceptibility to E 4031; beta-Cyclodextrins analog inhibits the reaction [E 4031 results in decreased activity of KCNH2 protein]; E 4031 binds to and results in decreased activity of KCNH2 protein; E 4031 inhibits the reaction [fexofenadine results in increased activity of KCNH2 protein mutant form]; E 4031 inhibits the reaction [Flufenamic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]; E 4031 inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; E 4031 inhibits the reaction [Niflumic Acid promotes the reaction [KCNH2 protein results in increased transport of Potassium]]; E 4031 results in decreased activity of [KCNE2 protein binds to KCNH2 protein]; E 4031 results in increased glycosylation of and affects the localization of KCNH2 protein mutant form
E 4031 binds to KCNH2 protein 		CTD PMID:10219239 PMID:10531299 PMID:11741928 PMID:12070109 PMID:12359267 More... NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
ebrotidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO ebrotidine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO ebrotidine results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO ebrotidine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
etebenecid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tas2r118 taste receptor, type 2, member 118 multiple interactions ISO 4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] CTD PMID:21629661 NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:53,414,815...53,415,714 		JBrowse link
G Tas2r138 taste receptor, type 2, member 138 multiple interactions ISO 4-((diethylamino)sulfonyl)benzoic acid inhibits the reaction [Phenylthiourea results in increased activity of TAS2R38 protein] CTD PMID:21629661 NCBI chr 4:70,395,042...70,396,037 JBrowse link
ethoxzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca1 carbonic anhydrase 1 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
famotidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions ISO Famotidine inhibits the reaction [ADCYAP1 protein affects the secretion of Acids] CTD PMID:20388963 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383 		JBrowse link
G Agt angiotensinogen multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in increased expression of AGT protein] CTD PMID:27645307 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases activity ISO Famotidine results in decreased activity of BRAF protein CTD PMID:20823850 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO Famotidine binds to and results in decreased activity of CA12 protein CTD PMID:30344913 NCBI chr 8:76,169,723...76,225,465
Ensembl chr 8:76,169,815...76,225,465 		JBrowse link
G Ca6 carbonic anhydrase 6 multiple interactions ISO Famotidine binds to and results in decreased activity of CA6 protein CTD PMID:30344913 NCBI chr 5:165,941,028...165,959,566
Ensembl chr 5:165,941,029...165,959,566 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Famotidine binds to and results in decreased activity of CA2 protein CTD PMID:30344913 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO Famotidine binds to and results in decreased activity of CA7 protein CTD PMID:30344913 NCBI chr19:435,520...444,927
Ensembl chr19:435,522...452,384 		JBrowse link
G Cat catalase multiple interactions EXP
ISO 		Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in decreased activity of CAT protein]]
Famotidine inhibits the reaction [Indomethacin results in decreased expression of CAT protein] 		CTD PMID:18726076 PMID:19034656 PMID:19497431 PMID:25926722 PMID:38447874 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein]] CTD PMID:12538815 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression 		ISO Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA]
Famotidine results in increased expression of CTNNB1 mRNA 		CTD PMID:31563592 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Famotidine results in increased expression of CXCL1 protein CTD PMID:12023551 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO Famotidine inhibits the reaction [CYP2C19 gene affects the susceptibility to Lansoprazole] CTD PMID:15963082 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Famotidine co-treated with Sucralfate] results in increased expression of FGF2 mRNA CTD PMID:17717918 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Famotidine results in increased expression of FGF21 protein CTD PMID:8774986 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA] CTD PMID:9187264 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]] CTD PMID:15363660 NCBI chr10:27,096,731...27,152,563
Ensembl chr10:27,096,740...27,152,442 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr  X:155,301,979...155,543,870
Ensembl chr  X:155,303,928...155,543,863 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr10:27,438,127...27,657,680
Ensembl chr10:27,438,238...27,655,171 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG1 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG1 protein]] CTD PMID:15363660 NCBI chr14:37,750,292...37,821,651
Ensembl chr14:37,750,292...37,989,945 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions EXP Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Famotidine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA3 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:15363660 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,876,926...26,965,523 		JBrowse link
G Gast gastrin affects expression
increases expression 		ISO
EXP 		Famotidine affects the expression of GAST protein
Famotidine results in increased expression of GAST protein 		CTD PMID:12503773 PMID:17652263 NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP Famotidine inhibits the reaction [GHRL protein results in increased secretion of Acids] CTD PMID:16838121 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:148,421,315...148,425,969 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Famotidine inhibits the reaction [Dizocilpine Maleate results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Famotidine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA] CTD PMID:31563592 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hrh2 histamine receptor H 2 multiple interactions
decreases activity
increases expression 		ISO
EXP 		[Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Metformin; Famotidine binds to and results in decreased activity of HRH2 protein; Famotidine inhibits the reaction [[Dimaprit binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]; Famotidine inhibits the reaction [[Histamine binds to and results in increased activity of HRH2 protein] which results in increased expression of FOS mRNA]
Famotidine results in decreased activity of HRH2 protein
[Famotidine binds to and results in decreased activity of HRH2 protein] which affects the susceptibility to Histamine
Famotidine results in increased expression of HRH2 protein 		CTD PMID:9187264 PMID:9681472 PMID:12832840 PMID:15961859 PMID:16632449 More... NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression
multiple interactions 		EXP Famotidine results in decreased expression of HSPA1A protein
Zinc Compounds analog inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein] 		CTD PMID:16945336 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]] CTD PMID:11752121 PMID:12364868 PMID:12538815 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]] 		CTD PMID:11752121 PMID:12364868 PMID:19277450 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]] CTD PMID:11752121 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121 PMID:12364868 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]] CTD PMID:11752121 PMID:12364868 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO Famotidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of [IL12A protein binds to IL12B protein]]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of ICAM1 protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of IFNG protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]] CTD PMID:11752121 PMID:12364868 PMID:16723495 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP 		[Famotidine co-treated with Sucralfate] results in decreased expression of IL1B mRNA
Famotidine inhibits the reaction [Ethanol results in increased expression of IL1B protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of IL1B mRNA] 		CTD PMID:17717918 PMID:27474069 PMID:27645307 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]] CTD PMID:19277450 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]] CTD PMID:19277450 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of IL6 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of IL6 protein] CTD PMID:17603938 PMID:27474069 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK1 protein] CTD PMID:17656145 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased phosphorylation of MAPK3 protein] CTD PMID:17656145 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Famotidine inhibits the reaction [Histamine results in increased expression of MMP1 mRNA]; Famotidine inhibits the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased expression of MMP9 mRNA]; Famotidine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of MMP9 protein] CTD PMID:17603938 PMID:22257724 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression 		ISO
EXP 		Famotidine inhibits the reaction [Acids results in increased activity of MPO protein]
Famotidine results in increased expression of MPO protein
Famotidine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]; Famotidine promotes the reaction [Chlorpheniramine results in decreased activity of MPO protein]; Quercetin promotes the reaction [Famotidine inhibits the reaction [Indomethacin results in increased activity of MPO protein]] 		CTD PMID:12023551 PMID:16091555 PMID:16437673 PMID:17603938 PMID:18726076 More... NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO Famotidine inhibits the reaction [Indomethacin results in increased expression of MYD88 protein] CTD PMID:38447874 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Famotidine inhibits the reaction [Indomethacin results in increased expression of NFKB1 protein] CTD PMID:38447874 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO Famotidine inhibits the reaction [Indomethacin results in increased expression of NFKB2 mRNA] CTD PMID:38447874 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637 		JBrowse link
G Nppb natriuretic peptide B decreases expression EXP Famotidine results in decreased expression of NPPB protein CTD PMID:30310171 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Ntf3 neurotrophin 3 multiple interactions EXP [Pyrilamine co-treated with Famotidine co-treated with ciproxifan] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; [Pyrilamine co-treated with Famotidine] inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Famotidine inhibits the reaction [Histamine results in increased expression of NTF3 protein] CTD PMID:21276809 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Famotidine co-treated with Indomethacin] promotes the reaction [Acetic Acid results in increased expression of PCNA protein]; Famotidine promotes the reaction [Acetic Acid results in increased expression of PCNA protein] CTD PMID:18853145 PMID:19251492 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha decreases expression EXP Famotidine results in decreased expression of PPP3CA protein CTD PMID:30310171 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression EXP Famotidine results in increased expression of PRDX3 protein CTD PMID:30310171 NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300 		JBrowse link
G Prl prolactin increases expression ISO Famotidine results in increased expression of PRL protein CTD PMID:8104296 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS1 mRNA] CTD PMID:27645307 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO 		Famotidine inhibits the reaction [Indomethacin results in increased expression of PTGS2 mRNA]
Famotidine inhibits the reaction [Indomethacin results in decreased expression of PTGS2 mRNA] 		CTD PMID:27645307 PMID:38447874 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Famotidine inhibits the reaction [Ethanol results in increased expression of RELA protein] CTD PMID:27474069 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 affects expression ISO Famotidine affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Famotidine affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,695,010...4,702,246 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein] CTD PMID:16401727 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions
increases uptake 		ISO Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Famotidine inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine]
SLC19A3 protein results in increased uptake of Famotidine 		CTD PMID:26528626 NCBI chr 9:91,723,799...91,747,499
Ensembl chr 9:91,724,718...91,754,991 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions
increases uptake
affects transport 		ISO
EXP 		Famotidine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
SLC22A1 protein results in increased uptake of Famotidine
SLC22A1 protein affects the transport of Famotidine 		CTD PMID:16006492 PMID:16141367 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake
multiple interactions 		ISO
EXP 		SLC22A2 protein results in increased uptake of Famotidine
Famotidine inhibits the reaction [SLC22A2 protein affects the transport of Tetraethylammonium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] 		CTD PMID:15496291 PMID:16006492 PMID:16141367 PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
decreases activity 		ISO Famotidine inhibits the reaction [SLC22A3 protein affects the transport of 1-Methyl-4-phenylpyridinium]; Famotidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
Famotidine results in decreased activity of SLC22A3 protein 		CTD PMID:16141367 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
increases uptake 		ISO
EXP 		estrone sulfate inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Famotidine inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]
Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Penicillin G inhibits the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Famotidine]
Famotidine inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] 		CTD PMID:15100168 PMID:15319347 PMID:15496291 PMID:16006492 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Famotidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Famotidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions ISO Famotidine inhibits the reaction [Acids affects the localization of TACR1 protein] CTD PMID:16091555 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:116,478,617...116,647,492 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Famotidine inhibits the reaction [Indomethacin results in increased expression of TLR4 protein] CTD PMID:38447874 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion 		ISO
EXP 		Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Famotidine results in increased secretion of TNF protein
Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]
Famotidine inhibits the reaction [Ethanol results in increased expression of TNF protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of TNF mRNA] 		CTD PMID:11752121 PMID:12538815 PMID:17603938 PMID:17698507 PMID:19277450 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
fasudil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle decreases expression ISO fasudil results in decreased expression of ACTA2 mRNA CTD PMID:22465603 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP fasudil results in increased phosphorylation of and results in increased activity of AKT1 protein CTD PMID:17761835 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Arg1 arginase 1 increases expression EXP fasudil results in increased expression of ARG1 protein CTD PMID:30462329 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arhgef11 Rho guanine nucleotide exchange factor 11 decreases expression ISO fasudil results in decreased expression of ARHGEF11 mRNA; fasudil results in decreased expression of ARHGEF11 protein CTD PMID:26172442 NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP fasudil inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein] CTD PMID:22429817 PMID:30088170 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression 		EXP fasudil inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
fasudil results in increased expression of BCL2 protein 		CTD PMID:17761835 PMID:22429817 PMID:30088170 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein CTD PMID:31935364 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP fasudil inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; fasudil inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA] CTD PMID:17761835 PMID:30088170 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO fasudil inhibits the reaction [Acetaminophen results in increased expression of CCL2 protein] CTD PMID:34078832 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP fasudil affects the reaction [Daunorubicin affects the expression of CDKN1B mRNA] CTD PMID:20037814 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cfl1 cofilin 1 decreases expression
multiple interactions 		ISO
EXP 		fasudil results in decreased expression of CFL1 mRNA
fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein]
fasudil results in decreased expression of and results in decreased phosphorylation of CFL1 protein 		CTD PMID:22062134 PMID:26172442 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions 		ISO fasudil results in decreased expression of COL1A1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA 		CTD PMID:22465603 PMID:31935364 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO fasudil results in decreased expression of COL3A1 mRNA CTD PMID:22465603 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein] CTD PMID:23376009 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Gap43 growth associated protein 43 multiple interactions EXP [fasudil co-treated with Methylmercury Compounds] results in increased expression of and results in increased phosphorylation of GAP43 protein CTD PMID:30462329 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO fasudil inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] CTD PMID:30831131 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmox1 heme oxygenase 1 affects expression ISO fasudil affects the expression of HMOX1 protein CTD PMID:26120273 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] CTD PMID:23376009 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il10 interleukin 10 increases expression EXP fasudil results in increased expression of IL10 protein CTD PMID:30462329 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP fasudil inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO 		fasudil inhibits the reaction [Methylmercury Compounds results in increased expression of IL1B protein]; fasudil inhibits the reaction [Paraquat results in increased expression of IL1B protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein]; fasudil inhibits the reaction [Paraquat results in increased secretion of IL1B protein]
fasudil inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] 		CTD PMID:30088170 PMID:30462329 PMID:30924981 PMID:34078832 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO 		fasudil inhibits the reaction [Methylmercury Compounds results in increased expression of IL6 protein]; fasudil inhibits the reaction [Paraquat results in increased expression of IL6 protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein]; fasudil inhibits the reaction [Paraquat results in increased secretion of IL6 protein]
fasudil inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] 		CTD PMID:30088170 PMID:30462329 PMID:30924981 PMID:34078832 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Limk2 LIM domain kinase 2 multiple interactions EXP fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of LIMK2 protein] CTD PMID:22062134 NCBI chr14:82,384,256...82,509,755
Ensembl chr14:82,435,480...82,509,644 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases expression ISO fasudil results in decreased expression of MAP3K7 protein CTD PMID:22465603 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP fasudil inhibits the reaction [methylmercuric chloride results in decreased expression of MAPT protein] CTD PMID:20869980 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108 		JBrowse link
G Mmp8 matrix metallopeptidase 8 affects expression ISO fasudil affects the expression of MMP8 mRNA CTD PMID:26120273 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729 		JBrowse link
G Mmp9 matrix metallopeptidase 9 affects expression ISO fasudil affects the expression of MMP9 mRNA CTD PMID:26120273 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of MPO protein] CTD PMID:30924981 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO fasudil results in decreased expression of MYH7 mRNA CTD PMID:22465603 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Myl1 myosin, light chain 1 multiple interactions EXP fasudil inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein] CTD PMID:37963515 Ensembl chr 9:75,887,227...75,907,971 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO 		fasudil inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein] 		CTD PMID:23376009 PMID:30924981 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP fasudil inhibits the reaction [Methylmercury Compounds results in increased expression of NOS2 protein] CTD PMID:30462329 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions EXP fasudil inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein] CTD PMID:16452496 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521 		JBrowse link
G Nppa natriuretic peptide A decreases expression ISO fasudil results in decreased expression of NPPA mRNA CTD PMID:22465603 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B decreases expression ISO fasudil results in decreased expression of NPPB mRNA CTD PMID:22465603 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Pkn2 protein kinase N2 decreases activity ISO fasudil results in decreased activity of PKN2 protein CTD PMID:10998351 NCBI chr 2:234,454,001...234,559,369
Ensembl chr 2:234,454,001...234,594,649 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions EXP fasudil inhibits the reaction [Norepinephrine results in increased phosphorylation of PPP1R12A protein]; fasudil inhibits the reaction [Paraquat results in increased phosphorylation of PPP1R12A protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form] CTD PMID:22429817 PMID:30088170 PMID:37963515 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO 		fasudil inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of RELA protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein] 		CTD PMID:23376009 PMID:30462329 PMID:30924981 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rho rhodopsin multiple interactions ISO
EXP 		fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of RHO mRNA]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of RHO protein]
fasudil inhibits the reaction [Paraquat results in increased expression of RHO protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of RHO mRNA]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of RHO protein]; fasudil inhibits the reaction [Paraquat results in increased expression of RHO protein] 		CTD PMID:30088170 PMID:30924981 NCBI chr 4:150,653,205...150,658,367
Ensembl chr 4:150,653,205...150,658,367 		JBrowse link
G Rhoa ras homolog family member A decreases expression
multiple interactions 		ISO fasudil results in decreased expression of RHOA mRNA; fasudil results in decreased expression of RHOA protein
fasudil inhibits the reaction [Acetaminophen results in increased expression of RHOA protein] 		CTD PMID:26172442 PMID:34078832 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression
multiple interactions 		ISO
EXP 		fasudil results in decreased expression of ROCK1 mRNA; fasudil results in decreased expression of ROCK1 protein
fasudil inhibits the reaction [Acetaminophen results in increased expression of ROCK1 protein]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK1 mRNA]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK1 protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK1 mRNA]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK1 protein]; fasudil inhibits the reaction [Paraquat results in increased expression of ROCK1 protein]
fasudil affects the reaction [Daunorubicin affects the expression of ROCK1 mRNA]; fasudil inhibits the reaction [Paraquat results in increased expression of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased activity of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ROCK1 mRNA] 		CTD PMID:20037814 PMID:22429817 PMID:23376009 PMID:26172442 PMID:30088170 More... NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 decreases activity
multiple interactions 		EXP
ISO 		fasudil results in decreased activity of ROCK2 protein
fasudil inhibits the reaction [Acetaminophen results in increased expression of ROCK2 protein]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK2 mRNA]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ROCK2 protein] 		CTD PMID:10998351 PMID:30924981 PMID:34078832 NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:45,407,965...45,502,771 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 decreases activity ISO fasudil results in decreased activity of RPS6KA1 protein CTD PMID:10998351 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases activity ISO fasudil results in decreased activity of RPS6KA5 protein CTD PMID:10998351 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases activity ISO fasudil results in decreased activity of RPS6KB1 protein CTD PMID:10998351 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein CTD PMID:31935364 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression ISO fasudil results in increased expression of SLC12A2 protein CTD PMID:21474433 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
G Snca synuclein alpha multiple interactions EXP fasudil inhibits the reaction [propionic acid results in increased expression of SNCA mRNA] CTD PMID:32481507 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315 		JBrowse link
G Syp synaptophysin multiple interactions EXP fasudil inhibits the reaction [Rotenone results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP protein] CTD PMID:22062134 PMID:32481507 NCBI chr  X:17,521,348...17,536,449
Ensembl chr  X:17,521,348...17,536,984 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions 		ISO
EXP 		fasudil results in decreased expression of TGFB1 protein
fasudil inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] 		CTD PMID:22465603 PMID:23376009 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [[propionic acid co-treated with fasudil] affects the susceptibility to Rotenone] which results in increased expression of TH mRNA CTD PMID:32481507 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO fasudil affects the expression of TIMP1 mRNA CTD PMID:22465603 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP
ISO 		fasudil inhibits the reaction [Paraquat results in decreased expression of TJP1 protein] CTD PMID:30088170 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tnf tumor necrosis factor affects expression
multiple interactions 		ISO
EXP 		fasudil affects the expression of TNF mRNA
fasudil inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
fasudil inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; fasudil inhibits the reaction [Paraquat results in increased secretion of TNF protein]
fasudil inhibits the reaction [Methylmercury Compounds results in increased expression of TNF protein]; fasudil inhibits the reaction [Paraquat results in increased expression of TNF protein] 		CTD PMID:26120273 PMID:30088170 PMID:30462329 PMID:30924981 PMID:34078832 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 multiple interactions ISO fasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC1 protein] CTD PMID:30831131 NCBI chr 8:105,142,931...105,193,842
Ensembl chr 8:105,142,931...105,193,826 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions ISO fasudil inhibits the reaction [Oxygen deficiency results in increased expression of TRPC6 protein] CTD PMID:30831131 NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304 		JBrowse link
G Vegfa vascular endothelial growth factor A affects expression ISO fasudil affects the expression of VEGFA mRNA CTD PMID:26120273 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
furosemide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Furosemide results in decreased activity of ABCB11 protein CTD PMID:39023798 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO
EXP 		Furosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]
[Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione] 		CTD PMID:12704183 PMID:19782883 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions
decreases activity 		ISO Furosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]
Furosemide results in decreased activity of ABCC3 protein 		CTD PMID:12704183 PMID:39023798 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases export
decreases activity
increases transport 		ISO ABCC4 protein results in increased export of Furosemide
Furosemide results in decreased activity of ABCC4 protein
ABCC4 protein results in increased transport of Furosemide 		CTD PMID:17135398 PMID:17939016 PMID:39023798 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 affects expression EXP Furosemide affects the expression of ADAMTS1 mRNA CTD PMID:16526316 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390 		JBrowse link
G Agt angiotensinogen increases expression ISO Furosemide results in increased expression of AGT protein modified form CTD PMID:18081357 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation EXP Furosemide affects the phosphorylation of AKT1 protein CTD PMID:17497460 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin multiple interactions
affects binding 		ISO [bucolome inhibits the reaction [Furosemide binds to ALB protein]] which affects the abundance of Furosemide; bucolome inhibits the reaction [Furosemide binds to ALB protein] CTD PMID:15640375 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Furosemide results in increased expression of ALDH1A1 mRNA CTD PMID:28138970 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Ang angiogenin affects expression EXP Furosemide affects the expression of ANG mRNA CTD PMID:16526316 NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106 		JBrowse link
G Angpt2 angiopoietin 2 affects expression EXP Furosemide affects the expression of ANGPT2 mRNA CTD PMID:16526316 NCBI chr16:77,790,760...77,841,241
Ensembl chr16:77,790,563...77,841,239 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 affects expression EXP Furosemide affects the expression of APAF1 mRNA CTD PMID:17497460 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Aqp2 aquaporin 2 increases expression EXP Furosemide results in increased expression of AQP2 mRNA; Furosemide results in increased expression of AQP2 protein CTD PMID:17584643 NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression EXP Furosemide affects the expression of ARC mRNA CTD PMID:17497460 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220 		JBrowse link
G Atm ATM serine/threonine kinase affects expression EXP Furosemide affects the expression of ATM mRNA CTD PMID:17497460 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 multiple interactions
increases expression 		EXP [Furosemide co-treated with Amiloride] results in increased expression of ATP6V1B1 protein
Furosemide results in increased expression of ATP6V1B1 protein 		CTD PMID:17311909 NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:117,781,444...117,800,103 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 increases expression EXP Furosemide results in increased expression of AVPR2 mRNA CTD PMID:17584643 NCBI chr  X:156,785,009...156,787,477
Ensembl chr  X:156,785,139...156,787,477 		JBrowse link
G Bad BCL2-associated agonist of cell death affects expression EXP Furosemide affects the expression of BAD mRNA CTD PMID:17497460 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 affects expression EXP Furosemide affects the expression of BAK1 mRNA CTD PMID:17497460 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects expression EXP Furosemide affects the expression of BAX mRNA CTD PMID:17497460 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor affects expression EXP Furosemide affects the expression of BCL10 mRNA CTD PMID:17497460 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression EXP Furosemide affects the expression of BCL2 mRNA CTD PMID:17497460 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2a1 BCL2-related protein A1 affects expression EXP Furosemide affects the expression of BCL2A1D mRNA CTD PMID:17497460 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890 		JBrowse link
G Bcl2l10 Bcl2-like 10 affects expression EXP Furosemide affects the expression of BCL2L10 mRNA CTD PMID:17497460 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:84,987,833...84,993,872 		JBrowse link
G Bcl2l11 Bcl2-like 11 affects expression EXP Furosemide affects the expression of BCL2L11 mRNA CTD PMID:17497460 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Bcl2l2 Bcl2-like 2 affects expression EXP Furosemide affects the expression of BCL2L2 mRNA CTD PMID:17497460 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379 		JBrowse link
G Bid BH3 interacting domain death agonist affects expression EXP Furosemide affects the expression of BID mRNA CTD PMID:17497460 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Bik BCL2-interacting killer affects expression EXP Furosemide affects the expression of BIK mRNA CTD PMID:17497460 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects expression EXP Furosemide affects the expression of BIRC2 mRNA CTD PMID:17497460 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects expression EXP Furosemide affects the expression of BIRC5 mRNA CTD PMID:17497460 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 affects expression EXP Furosemide affects the expression of BIRC6 mRNA CTD PMID:17497460 NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:26,474,843...26,668,507 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases secretion ISO BMAL1 gene mutant form results in decreased secretion of Furosemide CTD PMID:27056296 NCBI chr 1:176,766,222...176,864,741
Ensembl chr 1:176,829,305...176,864,739 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK affects expression EXP Furosemide affects the expression of BOK mRNA CTD PMID:17497460 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:101,670,625...101,681,833 		JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta decreases expression EXP Furosemide results in decreased expression of BSND mRNA CTD PMID:12759757 NCBI chr 5:126,480,590...126,489,389
Ensembl chr 5:126,480,592...126,489,389 		JBrowse link
G Calb1 calbindin 1 increases expression ISO Furosemide results in increased expression of CALB1 mRNA; Furosemide results in increased expression of CALB1 protein CTD PMID:17652376 NCBI chr 5:34,172,612...34,199,555
Ensembl chr 5:34,172,664...34,200,160 		JBrowse link
G Car2 carbonic anhydrase 2 decreases activity
increases expression 		ISO
EXP 		Furosemide results in decreased activity of CA2 protein
Furosemide results in increased expression of CA2 mRNA 		CTD PMID:16858005 PMID:28138970 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Casp1 caspase 1 affects expression EXP Furosemide affects the expression of CASP1 mRNA CTD PMID:17497460 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 affects expression EXP Furosemide affects the expression of CASP12 mRNA CTD PMID:17497460 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp14 caspase 14 affects expression EXP Furosemide affects the expression of CASP14 mRNA CTD PMID:17497460 NCBI chr 7:11,577,315...11,583,987
Ensembl chr 7:11,580,339...11,583,171 		JBrowse link
G Casp2 caspase 2 affects expression EXP Furosemide affects the expression of CASP2 mRNA CTD PMID:17497460 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 affects expression EXP Furosemide affects the expression of CASP3 mRNA CTD PMID:17497460 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp4 caspase 4 affects expression EXP Furosemide affects the expression of CASP4 mRNA CTD PMID:17497460 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727 		JBrowse link
G Casp6 caspase 6 affects expression EXP Furosemide affects the expression of CASP6 mRNA CTD PMID:17497460 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp8 caspase 8 affects expression EXP Furosemide affects the expression of CASP8 mRNA CTD PMID:17497460 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 affects expression EXP Furosemide affects the expression of CASP9 mRNA CTD PMID:17497460 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cd40 CD40 molecule affects expression EXP Furosemide affects the expression of CD40 mRNA CTD PMID:17497460 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd70 Cd70 molecule affects expression EXP Furosemide affects the expression of CD70 mRNA CTD PMID:17497460 NCBI chr 9:2,093,540...2,096,692
Ensembl chr 9:2,086,848...2,096,692 		JBrowse link
G Cdh5 cadherin 5 decreases expression EXP Furosemide results in decreased expression of CDH5 mRNA CTD PMID:16526316 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Chek1 checkpoint kinase 1 affects expression EXP Furosemide affects the expression of CHEK1 mRNA CTD PMID:17497460 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359 		JBrowse link
G Chek2 checkpoint kinase 2 affects expression EXP Furosemide affects the expression of CHEK2 mRNA CTD PMID:17497460 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667 		JBrowse link
G Chga chromogranin A increases expression EXP Furosemide results in increased expression of CHGA mRNA CTD PMID:16526316 NCBI chr 6:127,460,895...127,472,238
Ensembl chr 6:127,460,854...127,472,237 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression EXP Furosemide affects the expression of CIDEA mRNA CTD PMID:17497460 NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression EXP Furosemide affects the expression of CIDEB mRNA CTD PMID:17497460 NCBI chr15:33,222,135...33,226,407
Ensembl chr15:33,221,824...33,226,688 		JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression EXP Furosemide results in decreased expression of CLCNKA mRNA CTD PMID:12759757 NCBI chr 5:158,974,190...158,989,275
Ensembl chr 5:158,974,193...158,989,128 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP Furosemide results in decreased expression of COL18A1 mRNA CTD PMID:16526316 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain affects expression EXP Furosemide affects the expression of CRADD mRNA CTD PMID:17497460 NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:31,685,622...31,874,512 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression EXP Furosemide results in increased expression of CSF3 mRNA CTD PMID:16526316 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Furosemide results in decreased activity of CYP3A4 protein CTD PMID:39023798 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Dapk2 death-associated protein kinase 2 affects expression EXP Furosemide affects the expression of DAPK2 mRNA CTD PMID:17497460 NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:75,601,634...75,720,617 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Furosemide results in increased expression of DDIT3 mRNA CTD PMID:24813929 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha affects expression EXP Furosemide affects the expression of DFFA mRNA CTD PMID:17497460 NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728 		JBrowse link
G Efna5 ephrin A5 increases expression EXP Furosemide results in increased expression of EFNA5 mRNA CTD PMID:16526316 NCBI chr 9:109,763,786...110,042,396
Ensembl chr 9:109,767,252...110,042,348 		JBrowse link
G Fadd Fas associated via death domain affects expression EXP Furosemide affects the expression of FADD mRNA CTD PMID:17497460 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976 		JBrowse link
G Faslg Fas ligand affects expression EXP Furosemide affects the expression of FASLG mRNA CTD PMID:17497460 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fgf16 fibroblast growth factor 16 affects expression EXP Furosemide affects the expression of FGF16 mRNA CTD PMID:16526316 NCBI chr  X:74,882,863...74,893,598
Ensembl chr  X:74,882,995...74,944,246 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression EXP Furosemide results in decreased expression of FGF2 mRNA CTD PMID:16526316 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression EXP Furosemide results in increased expression of FGF4 mRNA CTD PMID:16526316 NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects expression EXP Furosemide affects the expression of FGFR4 mRNA CTD PMID:16526316 NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression EXP Furosemide results in increased expression of FLT1 mRNA CTD PMID:16526316 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO
EXP 		Furosemide results in increased expression of FOS protein
Losartan inhibits the reaction [Furosemide results in increased expression of FOS protein] 		CTD PMID:10760498 PMID:15528393 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP Furosemide results in decreased activity of G6PD protein CTD PMID:26820767 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases activity EXP Furosemide results in decreased activity of GABRA4 protein CTD PMID:15613639 NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,944,388...37,021,648 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP Furosemide results in decreased expression of GAD1 mRNA CTD PMID:14596865 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression EXP Furosemide affects the expression of GADD45A mRNA CTD PMID:17497460 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP Furosemide results in decreased activity of GSR protein CTD PMID:26820767 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMGB1 protein; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMGB1 protein CTD PMID:29860548 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		ISO
EXP 		Furosemide results in increased expression of HMOX1 mRNA
[Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of HMOX1 mRNA; [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMOX1 mRNA 		CTD PMID:24813929 PMID:29860548 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hrk harakiri, BCL2 interacting protein affects expression EXP Furosemide affects the expression of HRK mRNA CTD PMID:17497460 NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases activity EXP Furosemide results in decreased activity of HSD11B1 protein CTD PMID:11749789 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Furosemide results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Hus1 HUS1 checkpoint clamp component affects expression EXP Furosemide affects the expression of HUS1 mRNA CTD PMID:17497460 NCBI chr14:87,902,458...87,917,221
Ensembl chr14:87,902,458...87,917,134 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression EXP Furosemide results in decreased expression of ID1 mRNA CTD PMID:16526316 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression EXP Furosemide results in decreased expression of ID3 mRNA CTD PMID:16526316 NCBI chr 5:153,656,253...153,657,860
Ensembl chr 5:153,630,498...153,657,856 		JBrowse link
G Ifna1 interferon, alpha 1 increases expression EXP Furosemide results in increased expression of IFNA1 mRNA CTD PMID:16526316 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP Furosemide results in increased expression of IGF1 mRNA CTD PMID:16526316 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il10 interleukin 10 decreases secretion ISO Furosemide results in decreased secretion of IL10 protein CTD PMID:16612254 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il6 interleukin 6 decreases secretion ISO Furosemide results in decreased secretion of IL6 protein CTD PMID:16612254 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression EXP Furosemide results in decreased expression of ITGA5 mRNA CTD PMID:16526316 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305 		JBrowse link
G Kdr kinase insert domain receptor increases expression EXP Furosemide results in increased expression of KDR mRNA CTD PMID:16526316 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Lta lymphotoxin alpha affects expression EXP Furosemide affects the expression of LTA mRNA CTD PMID:17497460 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533 		JBrowse link
G Ltb lymphotoxin beta affects expression EXP Furosemide affects the expression of LTB mRNA CTD PMID:17497460 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,632,210...3,634,054 		JBrowse link
G Ltbr lymphotoxin beta receptor affects expression EXP Furosemide affects the expression of LTBR mRNA CTD PMID:17497460 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296 		JBrowse link
G Mdk midkine increases expression EXP Furosemide results in increased expression of MDK mRNA CTD PMID:16526316 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743 		JBrowse link
G Mdm2 MDM2 proto-oncogene affects expression EXP Furosemide affects the expression of MDM2 mRNA CTD PMID:17497460 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Msr1 macrophage scavenger receptor 1 increases expression EXP Furosemide results in increased expression of MSR1 mRNA CTD PMID:16526316 NCBI chr16:59,421,250...59,507,070
Ensembl chr16:59,421,057...59,507,070 		JBrowse link
G Mt1a metallothionein 1A increases expression ISO Furosemide results in increased expression of MT1 mRNA CTD PMID:24813929 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Naip5 NLR family, apoptosis inhibitory protein 5 affects expression EXP Furosemide affects the expression of NAIP5 mRNA CTD PMID:17497460 NCBI chr 2:33,289,785...33,342,807
Ensembl chr 2:33,282,466...33,323,401 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 affects expression EXP Furosemide affects the expression of NAIP2 mRNA CTD PMID:17497460 NCBI chr 2:33,241,520...33,293,184
Ensembl chr 2:33,241,521...33,276,859 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases localization
decreases response to substance 		ISO Furosemide results in increased localization of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to Furosemide 		CTD PMID:18078705 PMID:24813929 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein CTD PMID:29860548 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nol3 nucleolar protein 3 affects expression EXP Furosemide affects the expression of NOL3 mRNA CTD PMID:17497460 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Nos3 nitric oxide synthase 3 affects expression EXP Furosemide affects the expression of NOS3 mRNA CTD PMID:16526316 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nppa natriuretic peptide A decreases expression ISO Furosemide results in decreased expression of NPPA protein CTD PMID:2146706 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of NQO1 mRNA CTD PMID:29860548 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha affects expression EXP Furosemide affects the expression of PDGFRA mRNA CTD PMID:16526316 NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,360,028...33,408,516 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression EXP Furosemide results in increased expression of PDGFRB mRNA CTD PMID:16526316 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression EXP Furosemide results in increased expression of PECAM1 mRNA CTD PMID:16526316 NCBI chr10:92,090,263...92,152,002
Ensembl chr10:92,090,235...92,151,839 		JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Furosemide results in decreased expression of PF4 mRNA CTD PMID:16526316 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392 		JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity EXP Furosemide results in decreased activity of PGD protein CTD PMID:26820767 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pgf placental growth factor decreases expression EXP Furosemide results in decreased expression of PGF mRNA CTD PMID:16526316 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PINK1 protein CTD PMID:29860548 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:51,210,330...52,430,304 		JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions ISO PTGER4 protein affects the reaction [Furosemide results in increased expression of REN mRNA]; PTGER4 protein affects the reaction [Furosemide results in increased expression of REN protein] CTD PMID:15976003 NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression EXP Furosemide affects the expression of PTGS1 mRNA; Furosemide affects the expression of PTGS1 protein CTD PMID:11961000 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions
increases expression 		EXP Furosemide affects the expression of PTGS2 mRNA; Furosemide affects the expression of PTGS2 protein
[Furosemide results in increased expression of PTGS2 mRNA] which results in increased abundance of Prostaglandins; [rofecoxib results in decreased activity of PTGS2 protein] inhibits the reaction [Furosemide results in increased abundance of Prostaglandins]
Furosemide results in increased expression of PTGS2 mRNA; Furosemide results in increased expression of PTGS2 protein 		CTD PMID:11135058 PMID:11703585 PMID:11961000 PMID:19031110 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pth parathyroid hormone increases expression
multiple interactions 		EXP Furosemide results in increased expression of PTH protein
NPS R-467 inhibits the reaction [Furosemide results in increased expression of PTH protein] 		CTD PMID:15086907 NCBI chr 1:176,942,901...176,946,034
Ensembl chr 1:176,943,102...176,946,034 		JBrowse link
G Ptn pleiotrophin affects expression EXP Furosemide affects the expression of PTN mRNA CTD PMID:16526316 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482 		JBrowse link
G Ren renin multiple interactions
increases expression
increases secretion
increases activity 		ISO
EXP 		Furosemide inhibits the reaction [Ethinyl Estradiol results in increased expression of REN protein]; Indomethacin inhibits the reaction [Furosemide results in increased expression of REN protein]; Ketoprofen inhibits the reaction [Furosemide results in increased activity of REN protein]; Sulindac inhibits the reaction [Furosemide results in increased expression of REN protein]
Furosemide results in increased secretion of REN protein
Furosemide results in increased expression of REN mRNA; Furosemide results in increased expression of REN protein
PTGER4 protein affects the reaction [Furosemide results in increased expression of REN mRNA]; PTGER4 protein affects the reaction [Furosemide results in increased expression of REN protein] 		CTD PMID:599795 PMID:1924052 PMID:3530574 PMID:4028619 PMID:7954537 More... NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 affects expression EXP Furosemide affects the expression of RIPK1 mRNA CTD PMID:17497460 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Rpa3 replication protein A3 affects expression EXP Furosemide affects the expression of RPA3 mRNA CTD PMID:17497460 NCBI chr 4:37,270,966...37,273,997
Ensembl chr 4:37,270,966...37,274,183 		JBrowse link
G S100b S100 calcium binding protein B multiple interactions EXP [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]]; [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23880158 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G S100g S100 calcium binding protein G affects expression ISO Furosemide affects the expression of S100G mRNA CTD PMID:17652376 NCBI chr  X:35,337,636...35,340,205
Ensembl chr  X:35,337,675...35,340,205 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression EXP Furosemide results in increased expression of S1PR1 mRNA CTD PMID:16526316 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G Serpinb5 serpin family B member 5 increases expression EXP Furosemide results in increased expression of SERPINB5 mRNA CTD PMID:16526316 NCBI chr13:23,500,203...23,520,401
Ensembl chr13:23,500,198...23,520,400 		JBrowse link
G Serpinf1 serpin family F member 1 affects expression EXP Furosemide affects the expression of SERPINF1 mRNA CTD PMID:16526316 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases activity ISO Furosemide results in decreased activity of SLC10A1 protein CTD PMID:39023798 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases activity ISO Furosemide results in decreased activity of SLC12A1 protein CTD PMID:11249848 NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions
decreases activity 		EXP
ISO 		[Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]]; [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein]; [Furosemide results in decreased activity of SLC12A2 protein] promotes the reaction [Thioctic Acid results in decreased activity of Ammonia]; [Furosemide results in decreased activity of SLC12A2 protein] which results in decreased susceptibility to Ammonia; [Furosemide results in decreased activity of SLC12A2 protein] which results in increased activity of Ammonia
Furosemide inhibits the reaction [SLC12A2 protein results in increased uptake of Rubidium] 		CTD PMID:23880158 PMID:29959396 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
G Slc12a5 solute carrier family 12 member 5 decreases activity
multiple interactions 		EXP
ISO 		Furosemide results in decreased activity of SLC12A5 protein
Furosemide inhibits the reaction [SLC12A5 protein results in increased import of Thallium] 		CTD PMID:18094240 PMID:20086212 NCBI chr 3:174,115,833...174,155,112
Ensembl chr 3:174,115,833...174,155,112 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO Furosemide results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957 		JBrowse link
G Slc22a19 solute carrier family 22, member 19 multiple interactions EXP Furosemide inhibits the reaction [SLC22A19 protein affects the transport of estrone sulfate] CTD PMID:16079298 NCBI chr 1:214,339,594...214,394,681
Ensembl chr 1:214,339,599...214,394,681 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression
increases secretion
decreases activity 		EXP
ISO 		Furosemide results in increased expression of SLC22A6 protein
SLC22A6 protein results in increased secretion of Furosemide
Furosemide results in decreased activity of SLC22A6 protein 		CTD PMID:12897087 PMID:18216144 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO Furosemide inhibits the reaction [SLC22A7 protein results in increased transport of Tetracycline] CTD PMID:15901346 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity
multiple interactions
increases secretion 		ISO
EXP 		Furosemide results in decreased activity of SLC22A8 protein
Furosemide inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]
Furosemide inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
SLC22A8 protein results in increased secretion of Furosemide 		CTD PMID:10224140 PMID:11306713 PMID:18216144 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 multiple interactions
affects localization 		EXP [Furosemide co-treated with Amiloride] affects the localization of SLC26A4 protein
Furosemide affects the localization of SLC26A4 protein 		CTD PMID:17311909 NCBI chr 6:53,835,102...53,873,968
Ensembl chr 6:53,835,110...53,873,216 		JBrowse link
G Sparc secreted protein acidic and cysteine rich increases expression EXP Furosemide results in increased expression of SPARC mRNA CTD PMID:16526316 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP Furosemide results in increased expression of SPINK1 mRNA CTD PMID:28138970 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein; iodixanol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein]; Iohexol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein] CTD PMID:29860548 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases activity ISO Furosemide results in decreased activity of SULT2A1 protein CTD PMID:39023798 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Tek TEK receptor tyrosine kinase increases expression EXP Furosemide results in increased expression of TEK mRNA CTD PMID:16526316 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991 		JBrowse link
G Tgfa transforming growth factor alpha increases expression EXP Furosemide results in increased expression of TGFA mRNA CTD PMID:16526316 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression EXP Furosemide affects the expression of TGFB1 protein CTD PMID:18001696 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Furosemide results in increased expression of TGFB2 mRNA CTD PMID:16526316 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Furosemide results in increased expression of TGFBR1 mRNA CTD PMID:16526316 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:66,449,293...66,527,260 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP Furosemide results in increased expression of TGFBR2 mRNA CTD PMID:16526316 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Thbs1 thrombospondin 1 affects expression EXP Furosemide affects the expression of THBS1 mRNA CTD PMID:16526316 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Furosemide results in increased expression of THBS2 mRNA CTD PMID:16526316 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918 		JBrowse link
G Thbs3 thrombospondin 3 affects expression EXP Furosemide affects the expression of THBS3 mRNA CTD PMID:16526316 NCBI chr 2:176,919,549...176,931,357
Ensembl chr 2:176,919,230...176,931,357 		JBrowse link
G Thbs4 thrombospondin 4 affects expression EXP Furosemide affects the expression of THBS4 mRNA CTD PMID:16526316 NCBI chr 2:25,718,219...25,760,345
Ensembl chr 2:25,718,219...25,761,369 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 increases expression EXP Furosemide results in increased expression of TIE1 mRNA CTD PMID:16526316 NCBI chr 5:137,285,408...137,305,047
Ensembl chr 5:137,285,408...137,304,981 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 affects expression EXP Furosemide affects the expression of TIMP2 mRNA CTD PMID:16526316 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
affects expression 		ISO
EXP 		Furosemide results in decreased secretion of TNF protein
Furosemide affects the expression of TNF mRNA 		CTD PMID:16526316 PMID:16612254 PMID:17497460 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A affects expression EXP Furosemide affects the expression of TNFRSF11A mRNA CTD PMID:17497460 NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A affects expression EXP Furosemide affects the expression of TNFRSF1A mRNA CTD PMID:17497460 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B affects expression EXP Furosemide affects the expression of TNFRSF1B mRNA CTD PMID:17497460 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411 		JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 affects expression EXP Furosemide affects the expression of TNFRSF25 mRNA CTD PMID:17497460 NCBI chr 5:167,904,377...167,909,052
Ensembl chr 5:167,904,786...167,909,052 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 affects expression EXP Furosemide affects the expression of TNFRSF8 mRNA CTD PMID:17497460 NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:162,406,387...162,451,620 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 affects expression EXP Furosemide affects the expression of TNFRSF9 mRNA CTD PMID:17497460 NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:166,664,494...166,690,831 		JBrowse link
G Tnfsf10 TNF superfamily member 10 affects expression EXP Furosemide affects the expression of TNFSF10 mRNA CTD PMID:17497460 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnfsf11 TNF superfamily member 11 affects expression EXP Furosemide affects the expression of TNFSF11 mRNA CTD PMID:17497460 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tnfsf12 TNF superfamily member 12 affects expression EXP Furosemide affects the expression of TNFSF12 mRNA CTD PMID:17497460 NCBI chr10:54,902,616...54,912,628
Ensembl chr10:54,902,616...54,911,913 		JBrowse link
G Tnfsf13 TNF superfamily member 13 affects expression EXP Furosemide affects the expression of TNFSF13 mRNA CTD PMID:17497460 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815 		JBrowse link
G Tnfsf8 TNF superfamily member 8 affects expression EXP Furosemide affects the expression of TNFSF8 mRNA CTD PMID:17497460 NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:82,266,436...82,292,858 		JBrowse link
G Tnfsf9 TNF superfamily member 9 affects expression EXP Furosemide affects the expression of TNFSF9 mRNA CTD PMID:17497460 NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339 		JBrowse link
G Tpmt thiopurine S-methyltransferase decreases activity ISO Furosemide results in decreased activity of TPMT protein CTD PMID:8866635 NCBI chr17:17,850,308...17,868,976
Ensembl chr17:17,850,279...17,868,976 		JBrowse link
G Traf5 TNF receptor-associated factor 5 affects expression EXP Furosemide affects the expression of TRAF5 mRNA CTD PMID:17497460 NCBI chr13:106,100,921...106,149,724
Ensembl chr13:106,103,291...106,149,707 		JBrowse link
G Traf6 TNF receptor associated factor 6 affects expression EXP Furosemide affects the expression of TRAF6 mRNA CTD PMID:17497460 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 increases expression ISO Furosemide results in increased expression of TRPV5 mRNA; Furosemide results in increased expression of TRPV5 protein CTD PMID:17652376 NCBI chr 4:71,503,085...71,531,134
Ensembl chr 4:71,503,093...71,529,384 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases expression ISO Furosemide results in increased expression of TRPV6 mRNA CTD PMID:17652376 NCBI chr 4:71,474,006...71,489,667
Ensembl chr 4:71,474,007...71,489,671 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Furosemide results in increased expression of UGT1A1 mRNA CTD PMID:18227147 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation
decreases activity 		ISO UGT1A3 protein results in increased glucuronidation of Furosemide
Furosemide results in decreased activity of UGT1A3 protein 		CTD PMID:15117964 PMID:39023798 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Furosemide results in decreased activity of UGT2B7 protein CTD PMID:39023798 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Furosemide results in increased expression of VCAM1 mRNA CTD PMID:16526316 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vegfa vascular endothelial growth factor A affects expression EXP Furosemide affects the expression of VEGFA mRNA CTD PMID:16526316 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfc vascular endothelial growth factor C increases expression EXP Furosemide results in increased expression of VEGFC mRNA CTD PMID:16526316 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
G Xiap X-linked inhibitor of apoptosis affects expression EXP Furosemide affects the expression of XIAP mRNA CTD PMID:17497460 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
gliclazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in increased susceptibility to Gliclazide CTD PMID:22209866 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Gliclazide results in decreased activity of AKR1C3 protein CTD PMID:26362498 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Alb albumin affects binding
multiple interactions 		ISO
EXP 		Gliclazide binds to ALB protein
Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein] 		CTD PMID:14871415 PMID:20974553 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Gliclazide inhibits the reaction [Glucose results in decreased expression of BCL2 protein] CTD PMID:18088078 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression 		ISO
EXP 		Gliclazide inhibits the reaction [Glucose results in increased expression of CASP3 protein]
Gliclazide results in decreased expression of CASP3 mRNA
Gliclazide inhibits the reaction [Acetic Acid results in increased expression of CASP3 protein] 		CTD PMID:18088078 PMID:32045587 PMID:33652124 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase multiple interactions EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:20307516 PMID:20643114 PMID:21439372 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Gliclazide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A mRNA] CTD PMID:12646174 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein] CTD PMID:28330423 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein] CTD PMID:21439372 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Glo1 glyoxalase 1 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] CTD PMID:21439372 NCBI chr20:8,665,061...8,683,095
Ensembl chr20:8,665,061...8,683,191 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein] CTD PMID:20307516 PMID:21439372 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] CTD PMID:21439372 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP 		Gliclazide inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]
Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein] 		CTD PMID:12646174 PMID:21439372 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [Acetic Acid results in increased expression of ICAM1 protein] CTD PMID:14871415 PMID:32045587 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in decreased expression of IL10 protein] CTD PMID:32045587 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein] CTD PMID:20307516 PMID:20643114 PMID:21439372 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Acetic Acid results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein] CTD PMID:20307516 PMID:20643114 PMID:21439372 PMID:32045587 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP Gliclazide inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:28330423 PMID:28625491 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in increased susceptibility to Gliclazide CTD PMID:22209866 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein] CTD PMID:21439372 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK1 protein] CTD PMID:32045587 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK3 protein] CTD PMID:32045587 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in increased phosphorylation of MAPK8 protein] CTD PMID:32045587 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in increased activity of MPO protein] CTD PMID:32045587 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein] CTD PMID:14871415 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein] CTD PMID:21439372 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression EXP Gliclazide results in increased expression of NOS3 protein CTD PMID:14871415 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP Gliclazide inhibits the reaction [Acetic Acid results in decreased expression of PPARG protein] CTD PMID:32045587 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:20307516 PMID:20643114 PMID:21439372 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein] CTD PMID:14871415 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression 		EXP Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of TNF protein]
Gliclazide results in decreased expression of TNF protein 		CTD PMID:20307516 PMID:20643114 PMID:21439372 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO Gliclazide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP3 mRNA] CTD PMID:12646174 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Gliclazide results in increased expression of TP53 mRNA CTD PMID:33652124 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
glimepiride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions 		ISO glimepiride results in decreased activity of ABCB11 protein
glimepiride inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] 		CTD PMID:20829430 PMID:23956101 PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to glimepiride CTD PMID:22209866 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO glimepiride results in decreased activity of AKR1C1 protein CTD PMID:26362498 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO glimepiride results in decreased activity of AKR1C3 protein CTD PMID:26362498 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Capn1 calpain 1 increases expression ISO glimepiride results in increased expression of CAPN1 mRNA CTD PMID:33652124 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Capn10 calpain 10 increases expression ISO glimepiride results in increased expression of CAPN10 mRNA CTD PMID:33652124 NCBI chr 9:100,943,665...100,957,910
Ensembl chr 9:100,945,551...100,957,912 		JBrowse link
G Capn2 calpain 2 increases expression ISO glimepiride results in increased expression of CAPN2 mRNA CTD PMID:33652124 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression 		ISO glimepiride results in increased activity of CASP3 protein
glimepiride results in increased expression of CASP3 mRNA 		CTD PMID:33652124 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [glimepiride results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP [Plant Extracts co-treated with glimepiride] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; glimepiride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:26721197 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Ins2 insulin 2 decreases expression ISO glimepiride results in decreased expression of INS protein CTD PMID:15642492 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO [KCNJ11 mutant form co-treated with ABCC8 mutant form] results in decreased susceptibility to glimepiride CTD PMID:22209866 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions 		ISO glimepiride results in increased activity of NR1I2 protein
[glimepiride results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA 		CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO glimepiride affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO glimepiride affects the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin]; glimepiride affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO glimepiride inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin]; glimepiride inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein] CTD PMID:23121773 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO glimepiride results in increased expression of TP53 mRNA CTD PMID:33652124 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
glipizide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity 		ISO Glipizide inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Glipizide results in decreased activity of ABCB11 protein 		CTD PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Glipizide results in decreased activity of AKR1C1 protein CTD PMID:26362498 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Glipizide results in decreased activity of AKR1C2 protein CTD PMID:26362498 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Glipizide results in decreased activity of AKR1C3 protein CTD PMID:26362498 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
glyburide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
increases expression
decreases activity 		ISO
EXP 		[Glyburide results in decreased activity of ABCB11 protein] which results in decreased export of Taurodeoxycholic Acid; Glyburide inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
[Bile Acids and Salts co-treated with Glyburide] results in decreased expression of ABCB11 mRNA
Glyburide results in increased expression of ABCB11 mRNA
[Glyburide results in decreased activity of ABCB11 protein] which results in decreased export of Taurodeoxycholic Acid; [Glyburide results in decreased activity of ABCB11 protein] which results in decreased secretion of Rosuvastatin Calcium 		CTD PMID:11343252 PMID:15465654 PMID:15618715 PMID:19853032 PMID:20147439 More... NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Glyburide results in increased expression of ABCB4 mRNA CTD PMID:27765674 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO Glyburide results in decreased activity of ABCC1 protein CTD PMID:15652236 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP
ISO 		Glyburide results in increased expression of ABCC2 mRNA CTD PMID:27765674 PMID:35708773 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Glyburide results in increased expression of ABCC3 mRNA CTD PMID:27765674 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Glyburide results in increased expression of ABCC4 mRNA CTD PMID:35708773 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 increases response to substance
affects binding
multiple interactions 		EXP ABCC8 protein results in increased susceptibility to Glyburide
Glyburide binds to ABCC8 protein; Glyburide binds to ABCC8 protein mutant form
Adenosine Triphosphate deficiency inhibits the reaction [Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]]; Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein mutant form]; Estradiol inhibits the reaction [Glyburide binds to ABCC8 protein]; resveratrol inhibits the reaction [Glyburide binds to ABCC8 protein] 		CTD PMID:17138562 PMID:19095654 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:105,734,992...105,815,982 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects binding
decreases activity
multiple interactions 		ISO Glyburide binds to ABCC9 protein mutant form
Glyburide results in decreased activity of ABCC9 protein
[Glyburide results in decreased activity of ABCC9 protein] which results in increased expression of XDH protein; Estradiol inhibits the reaction [Glyburide binds to ABCC9 protein mutant form]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]]; resveratrol inhibits the reaction [Glyburide binds to ABCC9 protein] 		CTD PMID:17138562 PMID:19095654 PMID:22622455 PMID:28842488 NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
decreases export 		ISO 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of Glyburide]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide]; Genistein inhibits the reaction [ABCG2 protein results in increased export of Glyburide]; Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of Glyburide] CTD PMID:26850786 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Glyburide results in increased expression of ABCG5 mRNA CTD PMID:27765674 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Glyburide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of ACTA2 protein]] CTD PMID:35305975 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein] CTD PMID:36999408 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Glyburide inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein] CTD PMID:10799337 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions EXP
ISO 		Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of AIF1 protein]
Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of AIF1 protein] 		CTD PMID:32375810 PMID:32522579 PMID:32860822 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Glyburide results in decreased activity of AKR1C1 protein CTD PMID:26362498 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Glyburide results in decreased activity of AKR1C2 protein CTD PMID:26362498 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Glyburide results in decreased activity of AKR1C3 protein CTD PMID:26362498 NCBI chr17:71,020,884...71,037,779
Ensembl chr17:70,970,900...71,048,438 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Glyburide inhibits the reaction [sodium bisulfide results in increased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein] CTD PMID:21800153 PMID:26286522 PMID:33724628 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin affects binding
multiple interactions 		ISO
EXP 		Glyburide binds to ALB protein
Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein] 		CTD PMID:20974553 PMID:36510688 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO Glyburide promotes the reaction [1,2-linoleoylphosphatidylcholine results in increased secretion of APOA1 protein]; Glyburide promotes the reaction [Clofibrate results in increased secretion of APOA1 protein] CTD PMID:19717637 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Arg1 arginase 1 multiple interactions EXP
ISO 		Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of ARG1 mRNA]
Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ARG1 mRNA] 		CTD PMID:32522579 PMID:32860822 PMID:34052309 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein] CTD PMID:33724628 PMID:36510688 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [sodium bisulfide results in increased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:21800153 PMID:33724628 PMID:36510688 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Capn2 calpain 2 increases expression ISO Glyburide results in increased expression of CAPN2 mRNA CTD PMID:33652124 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Casp1 caspase 1 multiple interactions EXP
ISO 		[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [Paraquat results in increased expression of CASP1 protein]
Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [Ozone results in increased cleavage of CASP1 protein] 		CTD PMID:25338942 PMID:32167222 PMID:32375810 PMID:32522579 PMID:32860822 More... NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression 		EXP
ISO 		Glyburide inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Glyburide inhibits the reaction [soybean oil, phospholipid emulsion inhibits the reaction [Amlodipine results in increased cleavage of CASP3 protein]]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased activity of CASP3 protein]]
Glyburide results in increased activity of CASP3 protein
Glyburide results in increased expression of CASP3 mRNA 		CTD PMID:16310184 PMID:33030052 PMID:33652124 PMID:35305975 PMID:36504472 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; Glyburide inhibits the reaction [soybean oil, phospholipid emulsion inhibits the reaction [Amlodipine results in increased cleavage of CASP9 protein]] CTD PMID:33030052 PMID:36510688 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions ISO
EXP 		Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in decreased activity of CAT protein]] 		CTD PMID:23716880 PMID:24760747 PMID:26286522 PMID:26700463 PMID:26748309 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
decreases activity 		ISO
EXP 		Glyburide binds to and results in decreased activity of CFTR protein; Glyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]; Glyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]; Glyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]
Glyburide results in decreased activity of CFTR protein
Glyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein]
Glyburide inhibits the reaction [CFTR protein affects the transport of Bicarbonates]; Glyburide inhibits the reaction [CFTR protein affects the transport of Chlorides] 		CTD PMID:14502435 PMID:14967738 PMID:15131065 PMID:15236628 PMID:15371258 More... NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Glyburide results in decreased expression of COL1A1 mRNA CTD PMID:35708773 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Cp ceruloplasmin multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] CTD PMID:26748309 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Cst3 cystatin C multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein] CTD PMID:33387473 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA; Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]; pyrvinium inhibits the reaction [[Glyburide co-treated with Isoproterenol] results in increased expression of CTNNB1 mRNA]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of CTNNB1 protein]] CTD PMID:35305975 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CYBB protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB protein] CTD PMID:32375810 PMID:34052309 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Glyburide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Glyburide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:10799337 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]] CTD PMID:27890915 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of FN1 protein]] CTD PMID:35305975 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of FTH1 mRNA] CTD PMID:27246103 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein] CTD PMID:25641191 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein] CTD PMID:31345080 NCBI chr10:87,647,149...87,651,385
Ensembl chr10:87,647,062...87,653,453 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein] CTD PMID:25641191 PMID:31345080 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein] CTD PMID:29223569 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gsdmd gasdermin D multiple interactions EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased cleavage of GSDMD protein] CTD PMID:32522579 PMID:32860822 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein] CTD PMID:26748309 PMID:33724628 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone promotes the reaction [Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of HMGB1 protein]; Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of HMGB1 mRNA]; Glyburide inhibits the reaction [Ovalbumin results in increased expression of and results in increased secretion of HMGB1 protein]; Glyburide inhibits the reaction [Ovalbumin results in increased expression of HMGB1 mRNA] CTD PMID:29545090 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA] CTD PMID:30817903 PMID:36510688 PMID:36999408 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Glyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Glyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]; Glyburide inhibits the reaction [Ovalbumin results in decreased expression of IFNG protein] CTD PMID:11907163 PMID:29545090 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein] CTD PMID:36999408 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Glyburide inhibits the reaction [Ovalbumin results in decreased expression of IL10 protein] CTD PMID:29545090 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Glyburide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]; Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:11907163 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13 interleukin 13 multiple interactions ISO Glyburide inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:29545090 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il17a interleukin 17A multiple interactions EXP Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL17A protein]] CTD PMID:35305975 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 multiple interactions EXP
ISO 		Glyburide inhibits the reaction [Paraquat results in increased expression of IL18 protein]
Glyburide inhibits the reaction [Ozone results in increased expression of IL18 protein]; Glyburide inhibits the reaction [Paraquat results in increased secretion of IL18 protein] 		CTD PMID:25338942 PMID:32167222 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta affects secretion
multiple interactions 		ISO
EXP 		Glyburide affects the secretion of IL1B protein
Glyburide inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased secretion of IL1B protein]
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Paraquat results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of IL1B protein]]
Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Ozone results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Paraquat results in increased secretion of IL1B protein] 		CTD PMID:15578659 PMID:25338942 PMID:30817903 PMID:32167222 PMID:32375810 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone promotes the reaction [Glyburide inhibits the reaction [Ovalbumin results in increased expression of IL4 protein]]; Glyburide inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:29545090 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO Glyburide inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:29545090 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP 		Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein] 		CTD PMID:24760747 PMID:24849676 PMID:26748309 PMID:30817903 PMID:33724628 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions
increases secretion 		ISO
EXP 		Glyburide inhibits the reaction [Nanotubes, Carbon inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Glyburide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]
Glyburide results in increased secretion of INS1 protein
Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased secretion of INS1 protein] 		CTD PMID:26286522 PMID:26700463 PMID:26748309 PMID:29658312 PMID:30445784 More... NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Ins2 insulin 2 multiple interactions
increases response to substance
increases secretion
increases expression
decreases expression 		ISO
EXP 		[Glyburide co-treated with Glucose] results in increased expression of INS protein; Glyburide inhibits the reaction [Glucose results in decreased secretion of INS protein]; IRS1 protein polymorphism inhibits the reaction [Glyburide results in increased secretion of INS protein]
[Glyburide co-treated with Streptozocin] results in increased secretion of INS protein
Glyburide results in increased susceptibility to INS protein
Glyburide results in increased expression of INS mRNA
Glyburide results in decreased expression of INS protein 		CTD PMID:3116364 PMID:10430617 PMID:11305519 PMID:15066220 PMID:15642492 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Insr insulin receptor multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of INSR protein] CTD PMID:26286522 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein] CTD PMID:36504472 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO
EXP 		IRS1 protein polymorphism inhibits the reaction [Glyburide results in increased secretion of INS protein]
Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein] 		CTD PMID:10430617 PMID:26286522 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein] CTD PMID:26286522 PMID:33724628 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions EXP Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of ITGAM protein] CTD PMID:32522579 PMID:32860822 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Glyburide results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions
decreases response to substance 		ISO Glyburide inhibits the reaction [2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]]
KCNJ11 protein mutant form results in decreased susceptibility to Glyburide 		CTD PMID:15949470 PMID:28842488 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 decreases activity
decreases response to substance 		ISO
EXP 		Glyburide results in decreased activity of KCNJ8 protein
KCNJ8 protein mutant form results in decreased susceptibility to Glyburide 		CTD PMID:20050851 PMID:28842488 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:177,239,908...177,246,531 		JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 multiple interactions ISO Glyburide inhibits the reaction [KCNK18 protein results in increased transport of Potassium] CTD PMID:12754259 NCBI chr 1:268,360,738...268,375,012
Ensembl chr 1:268,360,738...268,375,012 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA] CTD PMID:30817903 PMID:36510688 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Lyz2 lysozyme 2 decreases secretion
increases secretion 		ISO Glyburide results in decreased secretion of LYZ protein
Glyburide results in increased secretion of LYZ protein 		CTD PMID:15194485 PMID:15234967 NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression 		EXP Quercetin promotes the reaction [Glyburide results in increased expression of MAPK1 protein modified form] CTD PMID:20860660 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression 		EXP Quercetin promotes the reaction [Glyburide results in increased expression of MAPK3 protein modified form] CTD PMID:20860660 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mbp myelin basic protein multiple interactions EXP Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MBP protein] CTD PMID:32522579 PMID:32860822 NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174 		JBrowse link
G Mir146a microRNA 146a multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA] CTD PMID:36504472 NCBI chr10:28,349,996...28,350,090 JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Glyburide inhibits the reaction [Paraquat results in increased activity of MPO protein]; Glyburide promotes the reaction [Isoproterenol results in increased activity of MPO protein] CTD PMID:25338942 PMID:35305975 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of MRC1 mRNA] CTD PMID:32522579 PMID:32860822 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NCF1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NCF1 protein] CTD PMID:32375810 PMID:34052309 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Glyburide inhibits the reaction [2,5-hexanedione results in decreased expression of NEFL protein] CTD PMID:32522579 PMID:32860822 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Glyburide inhibits the reaction [Lipopolysaccharides affects the localization of NFATC1 protein]; Glyburide inhibits the reaction [Lipopolysaccharides promotes the reaction [NFATC1 protein binds to NOS2 promoter]] CTD PMID:27246103 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA] CTD PMID:30817903 PMID:36510688 PMID:36999408 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein] CTD PMID:36999408 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP
ISO 		[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [Paraquat results in increased expression of NLRP3 protein]
Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [Ozone results in increased expression of NLRP3 protein] 		CTD PMID:25338942 PMID:32167222 PMID:32375810 PMID:32522579 PMID:32860822 More... NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP 		Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 protein]; Glyburide inhibits the reaction [Lipopolysaccharides promotes the reaction [NFATC1 protein binds to NOS2 promoter]]; Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glyburide inhibits the reaction [Pinacidil inhibits the reaction [Rotenone results in increased expression of and results in increased activity of NOS2 protein]]; KN 93 inhibits the reaction [Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA] 		CTD PMID:16257489 PMID:27246103 PMID:32375810 PMID:32522579 PMID:32860822 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]]; Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of NPPB protein]] CTD PMID:27890915 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP Glyburide results in decreased expression of NR1H4 mRNA CTD PMID:28391356 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA] CTD PMID:20363216 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pklr pyruvate kinase L/R multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA] CTD PMID:20363216 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG protein] CTD PMID:29223569 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] CTD PMID:30817903 PMID:36510688 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP Glyburide inhibits the reaction [Paraquat results in increased expression of PYCARD protein] CTD PMID:25338942 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:33724628 PMID:36504472 PMID:36510688 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression
multiple interactions 		EXP
ISO 		Glyburide results in decreased expression of SLC10A1 mRNA
[Bile Acids and Salts co-treated with Glyburide] results in decreased expression of SLC10A1 mRNA 		CTD PMID:27765674 PMID:28391356 PMID:35708773 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein] CTD PMID:33724628 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein] CTD PMID:26286522 PMID:29223569 PMID:33724628 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Glyburide promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of SLC6A3 protein] CTD PMID:16725203 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP Glyburide results in decreased expression of SLCO1A1 mRNA CTD PMID:27765674 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO Glyburide inhibits the reaction [SLCO1B3 protein results in increased uptake of Atorvastatin] CTD PMID:23121773 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Glyburide inhibits the reaction [SLCO2B1 protein results in increased uptake of Atorvastatin] CTD PMID:23121773 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279 		JBrowse link
G Snca synuclein alpha multiple interactions ISO Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] promotes the reaction [SNCA protein binds to SNCA protein]]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of SNCA protein] CTD PMID:32375810 PMID:34052309 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein] CTD PMID:36999408 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TGFB1 protein]] CTD PMID:35305975 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO Glyburide promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein] CTD PMID:16725203 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:36504472 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Pinacidil inhibits the reaction [Rotenone results in increased secretion of TNF protein]]
Glyburide inhibits the reaction [2,5-hexanedione results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNF protein]] 		CTD PMID:16257489 PMID:24760747 PMID:26748309 PMID:30817903 PMID:32375810 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]; pyrvinium inhibits the reaction [Glyburide promotes the reaction [Isoproterenol results in increased expression of TNNI3 protein]] CTD PMID:35305975 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression 		EXP
ISO 		Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 protein]
Glyburide results in increased expression of TP53 mRNA 		CTD PMID:30817903 PMID:33387473 PMID:33652124 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP Glyburide inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein] CTD PMID:36504472 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 decreases activity EXP
ISO 		Glyburide results in decreased activity of TRPM4 protein CTD PMID:16966582 PMID:17188667 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:104,918,462...104,948,653 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO [Glyburide results in decreased activity of ABCC9 protein] which results in increased expression of XDH protein CTD PMID:22622455 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
GR 113808 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr4 5-hydroxytryptamine receptor 4 multiple interactions
affects binding 		ISO
EXP 		GR 113808 binds to and results in decreased activity of HTR4 protein
GR 113808 binds to HTR4 protein 		CTD PMID:11020291 PMID:12736770 PMID:15236628 NCBI chr18:58,036,277...58,221,327
Ensembl chr18:58,036,277...58,219,622 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]] CTD PMID:30611738 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] CTD PMID:30611738 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:30611738 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions ISO GR 113808 inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in decreased expression of NAPEPLD protein]] CTD PMID:30611738 NCBI chr 4:14,251,591...14,291,010
Ensembl chr 4:14,252,692...14,291,014 		JBrowse link
hydrochlorothiazide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport
increases export 		ISO ABCC4 protein results in increased transport of Hydrochlorothiazide
ABCC4 protein results in increased export of Hydrochlorothiazide 		CTD PMID:17135398 PMID:17939016 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Ace angiotensin I converting enzyme increases expression
multiple interactions 		EXP Hydrochlorothiazide results in increased expression of ACE mRNA
Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of ACE mRNA] 		CTD PMID:16326922 PMID:18796534 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of ACTA1 mRNA] CTD PMID:16326922 NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Hydrochlorothiazide results in decreased expression of ADIPOQ mRNA CTD PMID:19730415 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression EXP Hydrochlorothiazide results in decreased expression of AGTR1A mRNA CTD PMID:18796534 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660 		JBrowse link
G Aqp2 aquaporin 2 decreases expression
multiple interactions 		EXP Hydrochlorothiazide results in decreased expression of AQP2 mRNA; Hydrochlorothiazide results in decreased expression of AQP2 protein
Hydrochlorothiazide inhibits the reaction [Lithium results in decreased expression of AQP2 protein] 		CTD PMID:15504936 PMID:17584643 NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 increases expression EXP Hydrochlorothiazide results in increased expression of ATP6V1B1 protein CTD PMID:17311909 NCBI chr 4:117,781,444...117,800,103
Ensembl chr 4:117,781,444...117,800,103 		JBrowse link
G Avp arginine vasopressin affects secretion ISO Hydrochlorothiazide affects the secretion of AVP protein CTD PMID:6635723 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 decreases expression EXP Hydrochlorothiazide results in decreased expression of AVPR2 mRNA CTD PMID:17584643 NCBI chr  X:156,785,009...156,787,477
Ensembl chr  X:156,785,139...156,787,477 		JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression EXP Hydrochlorothiazide results in decreased expression of BDKRB1 mRNA CTD PMID:18796534 NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973 		JBrowse link
G Cat catalase multiple interactions
decreases activity 		EXP [Hydrochlorothiazide co-treated with Fructose] results in decreased activity of CAT protein
Hydrochlorothiazide results in decreased activity of CAT protein 		CTD PMID:23707192 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Hydrochlorothiazide results in decreased expression of CCL2 mRNA CTD PMID:19627010 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of CDKN1B protein CTD PMID:11318962 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Cma1 chymase 1 affects expression EXP Hydrochlorothiazide affects the expression of CMA1 mRNA CTD PMID:18796534 NCBI chr15:33,387,351...33,390,133
Ensembl chr15:33,387,351...33,390,133 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of CYBA] CTD PMID:21107329 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of CYBB] CTD PMID:21107329 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression EXP Hydrochlorothiazide results in increased expression of CYP11B2 mRNA CTD PMID:18796534 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of EDN1 mRNA] CTD PMID:16326922 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions EXP [Hydralazine co-treated with Hydrochlorothiazide] inhibits the reaction [Cyclosporine results in increased expression of FLT1 mRNA] CTD PMID:12110003 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Klk1 kallikrein 1 increases expression EXP Hydrochlorothiazide results in increased expression of KLK1 mRNA CTD PMID:18796534 NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270 		JBrowse link
G Lepr leptin receptor increases response to substance ISO LEPR mutant form results in increased susceptibility to Hydrochlorothiazide CTD PMID:22949526 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Hydrochlorothiazide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of MYH7 mRNA] CTD PMID:16326922 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in decreased expression of NOS3 protein] CTD PMID:16197366 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of NOX1] CTD PMID:21107329 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP Hydrochlorothiazide promotes the reaction [candesartan results in decreased expression of NOX4] CTD PMID:21107329 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of NPPB mRNA] CTD PMID:16326922 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 increases expression EXP Hydrochlorothiazide results in increased expression of NR3C2 mRNA CTD PMID:18796534 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of PCNA protein CTD PMID:11318962 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [rofecoxib results in decreased activity of PTGS2 protein] inhibits the reaction [Hydrochlorothiazide results in increased abundance of Prostaglandins] CTD PMID:11703585 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ramp2 receptor activity modifying protein 2 multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of RAMP2 protein] CTD PMID:16326922 NCBI chr10:86,689,148...86,690,956
Ensembl chr10:86,688,703...86,691,231 		JBrowse link
G Ramp3 receptor activity modifying protein 3 multiple interactions EXP Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of RAMP3 protein] CTD PMID:16326922 NCBI chr14:85,741,314...85,758,813
Ensembl chr14:85,755,211...85,758,818 		JBrowse link
G Ren renin increases activity
multiple interactions
increases expression 		ISO
EXP 		Hydrochlorothiazide results in increased activity of REN protein
Losartan promotes the reaction [Hydrochlorothiazide results in increased expression of REN protein]; Sodium affects the reaction [Hydrochlorothiazide results in increased activity of REN protein] 		CTD PMID:1930859 PMID:2920503 PMID:11135058 PMID:12569265 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 affects expression ISO Hydrochlorothiazide affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-CE5 RT1 class I, locus CE5 affects expression ISO Hydrochlorothiazide affects the expression of HLA-F mRNA CTD PMID:25811541 NCBI chr20:3,407,880...3,484,130 JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects expression ISO Hydrochlorothiazide affects the expression of HLA-DRB1 mRNA CTD PMID:25811541 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G RT1-Ha RT1 class II, locus Ha affects expression ISO Hydrochlorothiazide affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,762,425...4,772,439
Ensembl chr20:4,763,033...4,772,141 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA; [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 increases expression EXP Hydrochlorothiazide results in increased expression of SLC22A6 protein CTD PMID:12897087 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
indapamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A increases expression ISO Indapamide results in increased expression of ADRA2A protein CTD PMID:2829625 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 affects expression ISO Indapamide affects the expression of ARHGAP45 mRNA CTD PMID:25811541 NCBI chr 7:10,325,515...10,340,955
Ensembl chr 7:10,325,539...10,341,890 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression EXP Indapamide affects the expression of FOS mRNA CTD PMID:11779033 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation EXP Indapamide affects the phosphorylation of MAPK1 protein CTD PMID:11779033 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation EXP Indapamide affects the phosphorylation of MAPK3 protein CTD PMID:11779033 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Ren renin increases expression ISO Indapamide results in increased expression of REN protein CTD PMID:6578003 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G RT1-DOa RT1 class II, locus DOa affects expression ISO Indapamide affects the expression of HLA-DOA mRNA CTD PMID:25811541 NCBI chr20:4,755,287...4,758,491
Ensembl chr20:4,755,499...4,758,478 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Indapamide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
KN-93 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO KN 93 inhibits the reaction [Digoxin results in increased expression of ABCB1 protein]; KN 93 inhibits the reaction [Ouabain results in increased expression of ABCB1 protein] CTD PMID:19647009 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Aco1 aconitase 1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride affects the localization of ACO1 protein] CTD PMID:25106854 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein] CTD PMID:32522522 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein] CTD PMID:18089838 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHRR mRNA] CTD PMID:18089838 NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:30,810,866...30,952,866 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein] CTD PMID:18506790 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO 		KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of AKT1 protein] 		CTD PMID:19233221 PMID:21933187 PMID:28025122 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein] CTD PMID:29883672 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions 		ISO KN 93 results in increased expression of ATF6 protein
KN 93 inhibits the reaction [Silicon Dioxide results in increased expression of ATF6 protein] 		CTD PMID:37075931 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of BAX mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of BAX protein] CTD PMID:34286406 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 mRNA]; KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 protein] CTD PMID:34286406 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H protein] CTD PMID:34286406 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,894,641...14,952,771 		JBrowse link
G Calcr calcitonin receptor multiple interactions ISO KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:32,615,955...32,691,075
Ensembl chr 4:32,615,958...32,691,075 		JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I decreases activity ISO KN 93 results in decreased activity of CAMK1 protein CTD PMID:12193581 NCBI chr 4:148,036,843...148,047,675
Ensembl chr 4:148,036,824...148,047,245 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions ISO
EXP 		[KN 93 co-treated with Losartan] inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]; KN 93 inhibits the reaction [bisphenol A results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [rutacarpine results in increased phosphorylation of CAMK2A protein]
KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]] 		CTD PMID:19217379 PMID:21933187 PMID:25103225 PMID:28025122 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP KN 93 inhibits the reaction [Cadmium affects the localization of CAMK2D protein] CTD PMID:22553113 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV multiple interactions EXP KN 93 inhibits the reaction [Tetrachlorodibenzodioxin affects the localization of CAMK4 protein] CTD PMID:17973980 NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193 		JBrowse link
G Casp12 caspase 12 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO 		KN 93 inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; KN 93 promotes the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]
KN 93 inhibits the reaction [rutecarpine inhibits the reaction [tert-Butylhydroperoxide results in increased activity of CASP3 protein]]
KN 93 inhibits the reaction [bisphenol A results in increased expression of and results in increased cleavage of CASP3 protein]; KN 93 inhibits the reaction [GW 7845 results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Vincristine results in increased cleavage of CASP3 protein] 		CTD PMID:19233221 PMID:20810541 PMID:26096086 PMID:26923100 PMID:28025122 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCL1 mRNA] CTD PMID:18089838 NCBI chr10:67,625,962...67,628,740
Ensembl chr10:67,625,962...67,628,790 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO KN 93 results in decreased expression of CCND1 protein CTD PMID:15958590 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; KN 93 inhibits the reaction [Nicotine results in increased phosphorylation of CREB1 protein] CTD PMID:15385614 PMID:15631885 PMID:21113126 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of CXCL12 mRNA] CTD PMID:34286406 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO KN 93 inhibits the reaction [GW 7845 affects the localization of CYCS protein] CTD PMID:20810541 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO KN 93 inhibits the reaction [Potassium results in increased expression of CYP11B2 mRNA] CTD PMID:12193581 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP 		KN 93 inhibits the reaction [STO 609 results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] CTD PMID:18089838 PMID:18755850 PMID:23298284 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] CTD PMID:18089838 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
decreases expression 		EXP
ISO 		KN 93 inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]
KN 93 results in decreased expression of DDIT3 protein 		CTD PMID:29883672 PMID:37075931 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; KN 93 inhibits the reaction [Excitatory Amino Acid Agents promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin promotes the reaction [CAMK2A protein modified form binds to DRD3 protein]]; KN 93 inhibits the reaction [Ionomycin results in increased phosphorylation of DRD3 protein] CTD PMID:19217379 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP
ISO 		KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein]
KN 93 inhibits the reaction [carvacrol results in increased phosphorylation of EGFR protein] 		CTD PMID:19233221 PMID:32535744 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21933187 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO KN 93 inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP
ISO 		KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]
KN 93 inhibits the reaction [Vincristine results in increased expression of GFAP protein] 		CTD PMID:21879721 PMID:34286406 NCBI chr10:88,352,987...88,361,661
Ensembl chr10:88,352,986...88,361,685 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 protein] CTD PMID:34286406 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression ISO KN 93 results in decreased expression of GPX4 protein CTD PMID:37075931 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP KN 93 inhibits the reaction [Capsaicin results in increased phosphorylation of GRIA1 protein] CTD PMID:12019337 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO KN 93 inhibits the reaction [Potassium Chloride results in increased phosphorylation of HDAC5 protein] CTD PMID:17988634 NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244 		JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP KN 93 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein] CTD PMID:14499669 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO KN 93 inhibits the reaction [Digoxin affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Digoxin results in increased phosphorylation of HIF1A protein]; KN 93 inhibits the reaction [Ouabain affects the localization of HIF1A protein]; KN 93 inhibits the reaction [Ouabain results in increased phosphorylation of HIF1A protein] CTD PMID:19647009 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 mRNA]; KN 93 inhibits the reaction [rutacarpine results in increased expression of HMOX1 protein] CTD PMID:28025122 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP KN 93 inhibits the reaction [cadmium acetate results in increased expression of HSPA5 protein] CTD PMID:29883672 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL1B mRNA]
KN 93 inhibits the reaction [Vincristine results in increased expression of IL1B mRNA] 		CTD PMID:18089838 PMID:34286406 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO KN 93 inhibits the reaction [Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]] CTD PMID:11809870 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of IL6 mRNA] CTD PMID:34286406 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgb7 integrin subunit beta 7 multiple interactions ISO KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB7 mRNA] CTD PMID:18089838 NCBI chr 7:135,225,962...135,243,522
Ensembl chr 7:135,226,555...135,243,597 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions EXP KN 93 inhibits the reaction [Phenylephrine results in increased activity of MAP3K5 protein] CTD PMID:15629441 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP 		KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK1 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK1 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK1 protein] 		CTD PMID:15086530 PMID:15355987 PMID:19233221 PMID:21879721 PMID:21933187 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein] CTD PMID:21933187 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP 		KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]; KN 93 promotes the reaction [wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]; wortmannin promotes the reaction [KN 93 inhibits the reaction [Zinc Sulfate results in increased phosphorylation of MAPK3 protein]]
KN 93 affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]
KN 93 inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of MAPK3 protein]; KN 93 inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of MAPK3 protein] 		CTD PMID:15086530 PMID:15355987 PMID:19233221 PMID:21879721 PMID:21933187 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein] CTD PMID:21933187 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Curcumin promotes the reaction [KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]]; KN 93 inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]; KN 93 promotes the reaction [Curcumin inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA]] CTD PMID:25093688 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21879721 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515 		JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr15:46,535,857...46,541,161
Ensembl chr15:46,535,517...46,541,163 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein] CTD PMID:32522522 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression ISO KN 93 results in decreased expression of NFATC2 protein CTD PMID:37075931 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP KN 93 inhibits the reaction [Phenylephrine results in increased degradation of NFKBIA protein] CTD PMID:15629441 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO KN 93 inhibits the reaction [Glyburide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]] CTD PMID:27246103 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of PTGS2 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of PTGS2 protein] CTD PMID:34286406 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO KN 93 results in decreased phosphorylation of RB1 protein CTD PMID:15958590 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased phosphorylation of RELA protein] CTD PMID:34286406 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21933187 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO KN 93 inhibits the reaction [Silicon Dioxide results in decreased expression of SLC7A11 protein] CTD PMID:37075931 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of SRC protein] CTD PMID:19233221 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions ISO KN 93 inhibits the reaction [carvacrol results in increased secretion of TGFA protein] CTD PMID:32535744 NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:120,175,593...120,258,339 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO KN 93 inhibits the reaction [Vincristine results in increased expression of TNF mRNA] CTD PMID:34286406 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of ACP5 protein]; KN 93 affects the reaction [[Cadmium co-treated with TNFSF11 protein co-treated with CSF1R protein] affects the expression of NFATC1 protein]; KN 93 inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 PMID:32522522 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Vim vimentin multiple interactions EXP KN 93 inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21879721 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Wnt5a Wnt family member 5A multiple interactions ISO KN 93 inhibits the reaction [Silicon Dioxide results in increased expression of WNT5A protein] CTD PMID:37075931 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860 		JBrowse link
Methazolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca1 carbonic anhydrase 1 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 decreases activity
multiple interactions 		ISO Methazolamide results in decreased activity of CA2 protein
Methazolamide binds to and results in decreased activity of CA2 protein 		CTD PMID:16858005 PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Clu clusterin affects expression ISO Methazolamide affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Methazolamide affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Methazolamide affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Ret ret proto-oncogene affects expression ISO Methazolamide affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
metolazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Metolazone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions 		ISO Metolazone results in increased activity of NR1I2 protein
[Metolazone results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA 		CTD PMID:25455453 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
metsulfuron methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions EXP metsulfuron methyl binds to and results in increased activity of AHR protein CTD PMID:14636698 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression EXP metsulfuron methyl results in decreased expression of ODC1 mRNA CTD PMID:15519604 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
ML-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle decreases expression
affects localization 		EXP
ISO 		ML 7 results in decreased expression of ACTA2
ML 7 affects the localization of ACTA2 protein 		CTD PMID:11591817 PMID:11868461 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO ML 7 results in decreased susceptibility to [quinocetone results in increased phosphorylation of AKT1 protein] CTD PMID:26446980 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased expression of BAX protein; ML 7 results in increased susceptibility to [quinocetone results in increased expression of BAX protein] CTD PMID:26446980 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases phosphorylation ISO ML 7 results in decreased phosphorylation of BCAR1 protein CTD PMID:18718759 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [ML 7 co-treated with quinocetone] results in decreased expression of BCL2 protein; ML 7 results in increased susceptibility to [quinocetone results in decreased expression of BCL2 protein] CTD PMID:26446980 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO ML 7 results in decreased expression of BIRC5 protein CTD PMID:18710790 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased cleavage of CASP3 protein; [ML 7 results in decreased activity of MYLK protein] which results in increased activity of CASP3 protein; FADD protein affects the reaction [[ML 7 results in decreased activity of MYLK protein] which results in increased activity of CASP3 protein] CTD PMID:16723733 PMID:26446980 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased cleavage of CASP8 protein; ML 7 results in increased susceptibility to [quinocetone results in increased cleavage of CASP8 protein] CTD PMID:26446980 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased cleavage of CASP9 protein; ML 7 results in increased susceptibility to [quinocetone results in increased cleavage of CASP9 protein] CTD PMID:26446980 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccna2 cyclin A2 multiple interactions EXP ML 7 inhibits the reaction [EGF protein results in increased expression of CCNA2 protein] CTD PMID:16799973 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression 		EXP
ISO 		ML 7 inhibits the reaction [EGF protein results in increased expression of CCND1 mRNA]; ML 7 inhibits the reaction [EGF protein results in increased expression of CCND1 protein]
ML 7 results in decreased expression of CCND1 protein 		CTD PMID:16799973 PMID:18710790 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccne1 cyclin E1 multiple interactions EXP ML 7 inhibits the reaction [EGF protein results in increased expression of CCNE1 protein] CTD PMID:16799973 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Cdh1 cadherin 1 decreases activity
affects localization 		ISO ML 7 results in decreased activity of CDH1 protein
ML 7 affects the localization of CDH1 protein 		CTD PMID:16030252 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions EXP ML 7 inhibits the reaction [EGF protein results in increased expression of CDK1 protein] CTD PMID:16799973 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO ML 7 results in decreased expression of CDKN1A protein CTD PMID:15252113 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO ML 7 results in increased expression of CDKN1B protein CTD PMID:15252113 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Col17a1 collagen type XVII alpha 1 chain affects localization ISO ML 7 affects the localization of COL17A1 protein CTD PMID:14691950 NCBI chr 1:256,472,648...256,518,857
Ensembl chr 1:256,472,648...256,518,851 		JBrowse link
G Csf2 colony stimulating factor 2 affects activity ISO ML 7 affects the activity of CSF2 protein CTD PMID:8471626 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Ctnnb1 catenin beta 1 affects localization
decreases expression 		ISO ML 7 affects the localization of CTNNB1 protein
ML 7 results in decreased expression of CTNNB1 protein 		CTD PMID:18710790 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO ML 7 inhibits the reaction [CXCL12 protein results in increased phosphorylation of MYL9 protein] CTD PMID:11751986 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Dst dystonin affects localization ISO ML 7 affects the localization of DST protein CTD PMID:14691950 NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP ML 7 inhibits the reaction [EGF protein affects the localization of MYL9 protein modified form]; ML 7 inhibits the reaction [EGF protein results in increased expression of CCNA2 protein]; ML 7 inhibits the reaction [EGF protein results in increased expression of CCND1 mRNA]; ML 7 inhibits the reaction [EGF protein results in increased expression of CCND1 protein]; ML 7 inhibits the reaction [EGF protein results in increased expression of CCNE1 protein]; ML 7 inhibits the reaction [EGF protein results in increased expression of CDK1 protein]; ML 7 inhibits the reaction [EGF protein results in increased expression of FOS protein]; ML 7 inhibits the reaction [EGF protein results in increased expression of JUN protein]; ML 7 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:16799973 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions
affects activity
decreases activity 		ISO
EXP 		ML 7 inhibits the reaction [F2 protein results in increased phosphorylation of MYL9 protein]
ML 7 affects the activity of F2 protein
[ML 7 results in decreased activity of MYLK protein] which results in decreased activity of F2 protein 		CTD PMID:1643115 PMID:14557824 PMID:15284075 PMID:16675616 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO FADD protein affects the reaction [[ML 7 results in decreased activity of MYLK protein] which results in increased activity of CASP3 protein] CTD PMID:16723733 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:209,169,318...209,174,976 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP ML 7 inhibits the reaction [EGF protein results in increased expression of FOS protein] CTD PMID:16799973 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP ML 7 inhibits the reaction [Ionomycin results in increased secretion of HEXB protein] CTD PMID:14499669 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO ML 7 inhibits the reaction [IL17A protein results in increased phosphorylation of MYL9 protein] CTD PMID:19940258 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions ISO ML 7 affects the localization of [ITGA3 protein binds to ITGB1 protein] CTD PMID:14691950 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:80,486,999...80,518,901 		JBrowse link
G Itga6 integrin subunit alpha 6 multiple interactions ISO ML 7 affects the localization of [ITGA6 protein binds to ITGB4 protein] CTD PMID:14691950 NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:77,017,766...77,097,076 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO ML 7 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] CTD PMID:19374788 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions
decreases activity 		ISO ML 7 affects the localization of [ITGA3 protein binds to ITGB1 protein]
ML 7 results in decreased activity of ITGB1 protein 		CTD PMID:14691950 PMID:16723733 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Itgb4 integrin subunit beta 4 multiple interactions ISO ML 7 affects the localization of [ITGA6 protein binds to ITGB4 protein] CTD PMID:14691950 NCBI chr10:101,705,592...101,741,933
Ensembl chr10:101,705,587...101,741,932 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP ML 7 inhibits the reaction [EGF protein results in increased expression of JUN protein] CTD PMID:16799973 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Lama3 laminin subunit alpha 3 affects localization ISO ML 7 affects the localization of LAMA3 protein CTD PMID:14691950 NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions 		ISO ML 7 results in decreased phosphorylation of MAPK1 protein
[ML 7 co-treated with quinocetone] results in increased phosphorylation of MAPK1 protein; ML 7 results in increased susceptibility to [quinocetone results in increased phosphorylation of MAPK1 protein] 		CTD PMID:18710790 PMID:26446980 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased phosphorylation of MAPK14 protein; ML 7 results in increased susceptibility to [quinocetone results in increased phosphorylation of MAPK14 protein] CTD PMID:26446980 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO ML 7 results in decreased phosphorylation of MAPK3 protein CTD PMID:18710790 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [ML 7 co-treated with quinocetone] results in increased phosphorylation of MAPK8 protein CTD PMID:26446980 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity 		EXP
ISO 		ML 7 inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]
ML 7 results in decreased activity of MPO protein 		CTD PMID:15863634 PMID:19374788 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO ML 7 results in decreased expression of MYC protein CTD PMID:18710790 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myh2 myosin heavy chain 2 affects localization
decreases activity 		ISO ML 7 affects the localization of MYH2 protein
ML 7 results in decreased activity of MYH2 protein 		CTD PMID:16030252 NCBI chr10:52,355,739...52,382,235
Ensembl chr10:52,355,739...52,382,235 		JBrowse link
G Myl7 myosin light chain 7 multiple interactions
decreases phosphorylation 		ISO ML 7 inhibits the reaction [Phenylephrine results in increased phosphorylation of MYL7 protein]
ML 7 results in decreased phosphorylation of MYL7 protein 		CTD PMID:15621049 NCBI chr14:84,994,644...84,997,173
Ensembl chr14:84,993,736...84,997,372 		JBrowse link
G Myl9 myosin light chain 9 multiple interactions
decreases phosphorylation
decreases expression 		ISO
EXP 		[ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein; ML 7 inhibits the reaction [CXCL12 protein results in increased phosphorylation of MYL9 protein]; ML 7 inhibits the reaction [F2 protein results in increased phosphorylation of MYL9 protein]; ML 7 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MYL9 protein]
ML 7 results in decreased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [IL17A protein results in increased phosphorylation of MYL9 protein]
[[ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein] which results in increased secretion of REN protein; [ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein; ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]; ML 7 inhibits the reaction [EGF protein affects the localization of MYL9 protein modified form]; ML 7 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MYL9 protein]
ML 7 results in decreased expression of MYL9 protein modified form 		CTD PMID:1643115 PMID:7503253 PMID:9618396 PMID:11751986 PMID:12745062 More... NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410 		JBrowse link
G Mylk myosin light chain kinase multiple interactions
decreases activity 		ISO
EXP 		[ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein; [ML 7 results in decreased activity of MYLK protein] which results in increased activity of CASP3 protein; FADD protein affects the reaction [[ML 7 results in decreased activity of MYLK protein] which results in increased activity of CASP3 protein]; ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein]; ML 7 inhibits the reaction [Ethanol results in increased activity of MYLK protein]
[[ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein] which results in increased secretion of REN protein; [ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Lipopolysaccharides results in increased expression of MYLK mRNA]; ML 7 inhibits the reaction [Lipopolysaccharides results in increased expression of MYLK protein]; ML 7 inhibits the reaction [MYLK protein results in increased uptake of Glucose]
[ML 7 results in decreased activity of MYLK protein] which results in decreased activity of F2 protein; ML 7 results in decreased activity of MYLK protein 		CTD PMID:1643115 PMID:9618396 PMID:10198341 PMID:10733514 PMID:11054866 More... NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO ML 7 results in decreased expression of MYOD1 protein CTD PMID:15252113 NCBI chr 1:106,021,161...106,023,871
Ensembl chr 1:106,021,161...106,023,871 		JBrowse link
G Myog myogenin decreases expression ISO ML 7 results in decreased expression of MYOG protein CTD PMID:15252113 NCBI chr13:48,297,476...48,300,065
Ensembl chr13:48,297,235...48,300,065 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NCF1 protein] CTD PMID:7575484 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Prkcb protein kinase C, beta decreases expression EXP ML 7 results in decreased expression of PRKCB protein CTD PMID:17272349 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases phosphorylation ISO ML 7 results in decreased phosphorylation of PTK2 protein CTD PMID:18718759 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Rac1 Rac family small GTPase 1 decreases activity
increases activity 		EXP ML 7 results in decreased activity of RAC1 protein
ML 7 results in increased activity of RAC1 protein 		CTD PMID:12105187 PMID:12745062 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Ren renin multiple interactions
increases secretion 		EXP [[ML 7 results in decreased activity of MYLK protein] which results in decreased phosphorylation of MYL9 protein] which results in increased secretion of REN protein; calyculin A inhibits the reaction [ML 7 results in increased secretion of REN protein]; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein] CTD PMID:9618396 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases activity ISO ML 7 results in decreased activity of RPS6KA5 protein CTD PMID:12534346 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO 		ML 7 inhibits the reaction [EGF protein results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]
ML 7 results in decreased susceptibility to [quinocetone results in increased phosphorylation of RPS6KB1 protein] 		CTD PMID:16799973 PMID:26446980 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions
decreases expression
decreases activity 		EXP ML 7 inhibits the reaction [SLC2A2 protein results in increased uptake of Glucose]
ML 7 results in decreased expression of SLC2A2 protein
ML 7 results in decreased activity of SLC2A2 protein 		CTD PMID:17272349 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO ML 7 inhibits the reaction [Oxygen deficiency affects the localization of TJP1 protein]
ML 7 inhibits the reaction [Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of TJP1 protein]] 		CTD PMID:20164382 PMID:33675858 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 decreases activity ISO ML 7 results in decreased activity of TRPC6 protein CTD PMID:17603544 NCBI chr 8:14,044,216...14,148,808
Ensembl chr 8:14,043,877...14,149,304 		JBrowse link
G Trpc7 transient receptor potential cation channel, subfamily C, member 7 increases activity ISO ML 7 results in increased activity of TRPC7 protein CTD PMID:17603544 NCBI chr17:7,707,954...7,839,064
Ensembl chr17:7,714,505...7,838,745 		JBrowse link
monodansylcadaverine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO monodansylcadaverine results in decreased phosphorylation of AKT1 protein CTD PMID:16170020 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO monodansylcadaverine results in decreased expression of BAD protein CTD PMID:16170020 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO monodansylcadaverine results in increased expression of BCL2L11 protein CTD PMID:16170020 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO monodansylcadaverine results in decreased expression of BIRC5 protein CTD PMID:16170020 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Ccl25 C-C motif chemokine ligand 25 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL25 protein] CTD PMID:22341560 NCBI chr12:7,505,231...7,514,402
Ensembl chr12:7,505,235...7,514,385 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL5 protein] CTD PMID:22341560 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL12 protein] CTD PMID:22341560 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO monodansylcadaverine results in decreased expression of GSK3B protein CTD PMID:16170020 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein]; monodansylcadaverine inhibits the reaction [IGF1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:20733350 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO monodansylcadaverine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL12B protein] CTD PMID:22341560 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL2 protein] CTD PMID:22341560 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il3 interleukin 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL3 protein] CTD PMID:22341560 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,906,460...38,908,810 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL4 protein] CTD PMID:22341560 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:22341560 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of IRF3 protein] CTD PMID:22341560 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:22341560 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:22341560 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:22341560 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of NFKB1 protein] CTD PMID:22341560 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Tgm2 transglutaminase 2 decreases activity ISO monodansylcadaverine results in decreased activity of TGM2 protein CTD PMID:16382148 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TICAM2 mRNA] CTD PMID:22341560 NCBI chr18:41,481,057...41,498,065
Ensembl chr18:41,478,539...41,512,243 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP1 protein] CTD PMID:22341560 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP4 protein] CTD PMID:22341560 NCBI chr 4:149,978,667...149,985,350
Ensembl chr 4:149,978,685...149,985,452 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of TLR4 protein] CTD PMID:22341560 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNFRSF1A protein] CTD PMID:22341560 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Zfp143 zinc finger protein 143 multiple interactions ISO monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein] CTD PMID:20733350 NCBI chr 1:173,543,810...173,579,667
Ensembl chr 1:173,543,863...173,579,660 		JBrowse link
N-(2,2,2-TRIFLUOROETHYL)-N-\{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL\}BENZENESULFONAMIDE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO
EXP 		T0901317 increases expression of ABCA1 mRNA in HepG2 cells
T0901317, LXR agonist, increases expression of abca1 mRNA and protein in rat hepatoma cells and fibroblasts 		RGD PMID:27765770 PMID:17526932 RGD:18936994, RGD:2308820 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide promotes the reaction [TNFSF10 protein results in increased expression of BIRC2 protein] CTD PMID:15520213 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide affects the localization of and results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:15520213 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 decreases activity ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide results in decreased activity of CSNK1A1 protein CTD PMID:15520213 NCBI chr18:57,285,156...57,320,540
Ensembl chr18:57,287,412...57,320,538 		JBrowse link
G Tbx3 T-box transcription factor 3 decreases expression ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide results in decreased expression of TBX3 mRNA CTD PMID:15255957 NCBI chr12:42,540,378...42,555,490
Ensembl chr12:42,540,378...42,554,171 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide results in increased expression of TNFRSF10A protein CTD PMID:15520213 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide promotes the reaction [TNFSF10 protein results in increased expression of BIRC2 protein]; N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide promotes the reaction [TNFSF10 protein results in increased expression of XIAP protein] CTD PMID:15520213 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions ISO N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide promotes the reaction [TNFSF10 protein results in increased expression of XIAP protein] CTD PMID:15520213 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca1 carbonic anhydrase 1 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity 		ISO Methazolamide binds to and results in decreased activity of CA2 protein
Methazolamide results in decreased activity of CA2 protein 		CTD PMID:16858005 PMID:17826101 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Clu clusterin affects expression ISO Methazolamide affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Methazolamide affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Methazolamide affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Ret ret proto-oncogene affects expression ISO Methazolamide affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:152,998,812...153,040,556 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in decreased phosphorylation of BAD protein] CTD PMID:16935404 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Mustard Gas results in increased cleavage of and results in increased activity of CASP3 protein]
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in increased cleavage of CASP3 protein] 		CTD PMID:16935404 PMID:27481217 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [ferric ammonium citrate results in decreased phosphorylation of DNM1L protein] CTD PMID:27481217 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420 		JBrowse link
G Hexb hexosaminidase subunit beta increases secretion
multiple interactions 		EXP N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in increased secretion of HEXB protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Ionomycin results in increased secretion of HEXB protein] 		CTD PMID:14499669 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases expression
multiple interactions 		ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide results in decreased expression of IL2RA protein
N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide inhibits the reaction [Pentoxifylline results in decreased expression of IL2RA protein] 		CTD PMID:1709825 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO N-(4-aminobutyl)-5-chloro-2-naphthalenesulfonamide affects the reaction [PDK1 protein affects the abundance of Cyclic AMP] CTD PMID:28887310 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145 		JBrowse link
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [aranidipine results in increased expression of ABCA1 protein] CTD PMID:16306803 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCB11 mRNA]] CTD PMID:27743861 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of ABCB1 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of ABCB1 protein 		CTD PMID:12926078 PMID:23466342 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in decreased expression of ABCB4 mRNA] CTD PMID:12926078 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Taurolithocholic Acid results in decreased activity of ABCC2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]] 		CTD PMID:26049102 PMID:27743861 PMID:31300867 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA] CTD PMID:18198219 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:120,550,328...120,556,383 		JBrowse link
G Adm adrenomedullin multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADM protein results in decreased activity of MAPK1 protein] CTD PMID:10374718 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Adora2b adenosine A2B receptor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADORA2B protein inhibits the reaction [Ethanol results in increased phosphorylation of RELA protein]] CTD PMID:35143882 NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]] CTD PMID:17823304 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Akna AT-hook transcription factor multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of AKNA mRNA] CTD PMID:29079362 NCBI chr 5:81,792,928...81,839,936
Ensembl chr 5:81,792,929...81,831,528 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases activity
affects phosphorylation 		ISO
EXP 		SB 203580 inhibits the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the phosphorylation of AKT1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased phosphorylation of AKT1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of AKT1 protein 		CTD PMID:10998351 PMID:17640974 PMID:32489702 PMID:39233265 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased expression of APOE mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased expression of CETP mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased secretion of APOE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased secretion of CETP protein] CTD PMID:22056562 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased expression of APOE mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased secretion of APOE protein] CTD PMID:22056562 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of AQP3 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [VIP protein results in increased expression of AQP3 mRNA] CTD PMID:12542607 NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:61,035,166...61,040,685 		JBrowse link
G Areg amphiregulin multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of AREG protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG protein] CTD PMID:15967414 PMID:16888076 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of ATF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased phosphorylation of ATF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased phosphorylation of ATF1 protein] CTD PMID:12164941 PMID:16671086 PMID:22188298 NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of ATF3 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of ATF3 protein] 		CTD PMID:25136830 PMID:30409902 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
decreases activity 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the localization of and results in decreased phosphorylation of BAD protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [BAD protein binds to BCL2L1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of BAD protein 		CTD PMID:12629175 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [BAD protein binds to BCL2L1 protein] CTD PMID:12629175 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein] CTD PMID:18377872 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Adenosine results in increased expression of BMP4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cordycepin results in increased expression of BMP4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [WNT3A protein results in increased expression of BMP4 mRNA] CTD PMID:34070360 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CASK protein] CTD PMID:20067577 NCBI chr  X:11,572,328...11,915,831
Ensembl chr  X:11,572,636...11,911,948 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased cleavage of CASP3 protein] 		CTD PMID:21873648 PMID:32115946 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased expression of CCL2] CTD PMID:11342529 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of CCND1 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein] 		CTD PMID:17680988 PMID:22493441 PMID:26964897 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD68 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD68 protein]] CTD PMID:27261088 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cd86 CD86 molecule multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD86 mRNA]] CTD PMID:27261088 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of CDKN1A mRNA] CTD PMID:16361081 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of CDKN2B mRNA] CTD PMID:16361081 NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPA mRNA] CTD PMID:17407152 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of CEBPB mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CEBPB mRNA] CTD PMID:14684744 PMID:21220312 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
decreases activity
affects localization 		ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of CFTR protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the localization of CFTR protein 		CTD PMID:12606488 PMID:14744818 PMID:14967738 PMID:15763242 PMID:15994425 More... NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF2 protein] CTD PMID:26125464 NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:54,235,019...54,295,464 		JBrowse link
G Chi3l3 chitinase 3-like 3 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of CHI3L3 mRNA] CTD PMID:27261088 NCBI chr 2:196,496,456...196,513,834
Ensembl chr 2:196,496,454...196,513,836 		JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sodium Benzoate results in increased expression of CNTF protein] CTD PMID:26399250 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:219,312,512...219,314,488 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] CTD PMID:11576339 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in decreased expression of COL2A1 protein] CTD PMID:21177286 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]] CTD PMID:11576339 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased expression of CPT1A mRNA] CTD PMID:19053045 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Adenosine results in increased expression of CREB1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased phosphorylation of and results in increased activity of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cordycepin results in increased expression of CREB1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [WNT3A protein results in increased expression of CREB1 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein promotes the reaction [Testosterone results in increased phosphorylation of CREB1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Roflumilast promotes the reaction [Nitroprusside results in increased phosphorylation of CREB1 protein]]
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [alternariol results in increased expression of CREB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [O-1602 compound results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sodium Benzoate results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in decreased expression of CREB1 mRNA] 		CTD PMID:10908723 PMID:12164941 PMID:15385614 PMID:15522277 PMID:16159392 More... NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crebbp CREB binding protein multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sodium Oxybate results in increased phosphorylation of CREBBP protein] CTD PMID:16675135 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CRTC2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of CRTC2 protein] CTD PMID:33359577 NCBI chr 2:178,007,233...178,017,397
Ensembl chr 2:178,007,240...178,017,389 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein] 		CTD PMID:22493441 PMID:26964897 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [3',4'-dimethoxyflavone results in increased expression of CYP11B1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased expression of CYP11B1 mRNA] CTD PMID:22172629 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Water Pollutants, Chemical analog results in increased expression of CYP19A1 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein] 		CTD PMID:19147701 PMID:20096755 PMID:20678559 PMID:21932247 PMID:28571770 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein] 		CTD PMID:20093341 PMID:25233930 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithocholic Acid results in increased activity of DIO2 protein] CTD PMID:19036883 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dopamine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein] CTD PMID:14622123 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine] CTD PMID:14759557 PMID:15245872 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Edn3 endothelin 3 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA] CTD PMID:22493441 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egr1 early growth response 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of EGR1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin results in increased expression of EGR1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin results in increased expression of EGR1 protein] CTD PMID:15621046 PMID:22174042 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Ereg epiregulin multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of EREG mRNA] CTD PMID:16888076 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Colforsin results in increased expression of ERVFRD-1 mRNA] CTD PMID:35908931 NCBI chr12:27,787,680...27,794,732
Ensembl chr12:27,787,680...27,794,732 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cyclic AMP results in increased activity of ESR1 protein] CTD PMID:20360387 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD68 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD68 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [F2 protein results in increased expression of CD86 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of CHI3L3 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of MRC1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of MRC1 protein] CTD PMID:27261088 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of FAS mRNA] CTD PMID:12414803 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of FOS mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of FOS mRNA]
[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOS mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] 		CTD PMID:10864209 PMID:15179140 PMID:21177286 PMID:31068361 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of FOSL1 mRNA] CTD PMID:21177286 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of FOSL2 mRNA] CTD PMID:21177286 NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Estradiol]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[FSHB protein co-treated with Testosterone] results in increased chemical synthesis of Progesterone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased expression of AREG protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased secretion of Progesterone]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein promotes the reaction [Testosterone results in increased phosphorylation of CREB1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased phosphorylation of TSC2 protein] 		CTD PMID:15967414 PMID:17510244 PMID:18535249 PMID:21177760 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Gast gastrin decreases secretion EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased secretion of GAST protein CTD PMID:19208342 NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,765,216...85,767,880 		JBrowse link
G Gcg glucagon multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein] CTD PMID:26964897 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:67,522,489...67,531,533 		JBrowse link
G Gcm1 glial cells missing transcription factor 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of GCM1 protein] CTD PMID:16166624 NCBI chr 8:87,805,993...87,819,229
Ensembl chr 8:87,805,993...87,819,229 		JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in decreased expression of GH1 mRNA] CTD PMID:29079362 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein] 		CTD PMID:22645130 PMID:37372083 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:24910983 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Acetaminophen results in decreased expression of and results in decreased activity of GPX1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [roflupram inhibits the reaction [Copper Sulfate results in decreased expression of GPX1 protein]] 		CTD PMID:24910983 PMID:37353053 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dopamine results in increased activity of DRD1 protein] which results in increased phosphorylation of GRIN1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of GRIN1 protein] CTD PMID:14622123 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:28,501,836...28,528,754 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of GRIN2B protein] CTD PMID:20067577 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570 		JBrowse link
G Gsdmd gasdermin D multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of GSDMD mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of GSDMD protein] CTD PMID:37353053 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Caffeine results in increased phosphorylation of GSK3B protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased phosphorylation of GSK3B protein] 		CTD PMID:21229324 PMID:39233265 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Has2 hyaluronan synthase 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of HAS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA] CTD PMID:21220312 NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of HMOX1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ferric ammonium citrate results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [hexacyanoferrate III results in increased expression of HMOX1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Nitroprusside results in increased expression of HMOX1 protein] 		CTD PMID:15179140 PMID:16439612 PMID:19483313 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of HSD11B1 mRNA] CTD PMID:33581290 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432 		JBrowse link
G Id1 inhibitor of DNA binding 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ID1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Iloprost results in increased expression of ID1 mRNA] CTD PMID:20522807 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Ighe immunoglobulin heavy constant epsilon multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA] CTD PMID:12230500
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] CTD PMID:17407152 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cimetidine results in increased expression of IL18 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of IL18 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL18 protein] 		CTD PMID:16723495 PMID:37353053 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of IL1B protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL1B protein] 		CTD PMID:23284918 PMID:29079362 PMID:37353053 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il4 interleukin 4 multiple interactions
decreases secretion
decreases expression 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA alternative form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [IL4 protein results in increased expression of IGHE mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased secretion of IL4 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL4 mRNA 		CTD PMID:11886533 PMID:12230500 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 decreases expression
decreases secretion 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of IL5 mRNA
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased secretion of IL5 protein 		CTD PMID:11886533 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of IL6 protein] CTD PMID:23284918 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in decreased expression of PLIN2 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of LIPE protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of LIPE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PNPLA2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PPARGC1A protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of UCP1 protein] CTD PMID:29288687 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IRS1 mRNA] CTD PMID:17407152 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2-(2-fluorobenzamido)benzoate ethyl ester inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGAM protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Rolipram inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGAM protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of ITGAM protein] CTD PMID:21457779 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP 		[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUN mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] 		CTD PMID:15179140 PMID:18755854 PMID:21177286 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with U 0126] inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased expression of JUNB mRNA] CTD PMID:21177286 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dobutamine results in increased activity of [JUN protein binds to JUND protein binds to FOS protein]] CTD PMID:15179140 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]] CTD PMID:16909339 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:45,064,162...45,081,247 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in decreased expression of KCNH2 protein] CTD PMID:22853924 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in decreased expression of KCNJ2 protein] CTD PMID:22853924 NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased activity of [KCNQ1 protein binds to KCNE1 protein]] CTD PMID:16909339 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:207,721,131...208,054,072 		JBrowse link
G Kng1 kininogen 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:15750287 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148 		JBrowse link
G Lep leptin multiple interactions
decreases response to substance 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased expression of CCL2]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased susceptibility to LEP protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Simvastatin results in decreased expression of LEP mRNA] 		CTD PMID:11342529 PMID:19254925 PMID:28571770 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased expression of AREG protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased secretion of Progesterone] 		CTD PMID:15967414 PMID:21220312 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of LIPE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of LIPE protein modified form]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of LIPE protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of LIPE mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Thioctic Acid results in increased phosphorylation of LIPE protein] CTD PMID:22941773 PMID:23362264 PMID:29288687 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Selegiline results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of MAPK1 protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Levodopa results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADM protein results in decreased activity of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK1 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Nitroprusside results in increased phosphorylation of MAPK1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK1 protein modified form]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in increased phosphorylation of and results in increased activity of MAPK1 protein 		CTD PMID:10374718 PMID:11675405 PMID:12657697 PMID:16099847 PMID:16439612 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of MAPK3 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the reaction [Levodopa results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Methyl-3-isobutylxanthine promotes the reaction [FSHB protein inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein promotes the reaction [1-Methyl-3-isobutylxanthine inhibits the reaction [Testosterone results in increased phosphorylation of MAPK3 protein]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Nitroprusside results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Quercetin promotes the reaction [Glucose results in increased expression of MAPK3 protein modified form]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Ro 31-8425 inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; Ro 31-8425 promotes the reaction [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Capsaicin results in increased phosphorylation of MAPK3 protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[GPER1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Selegiline results in increased phosphorylation of MAPK3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of MAPK3 protein]] 		CTD PMID:11675405 PMID:12657697 PMID:15385614 PMID:16099847 PMID:16439612 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [isosakuranetin results in increased expression of MITF protein] CTD PMID:26524968 NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin inhibits the reaction [Fructose results in increased activity of MLXIPL protein]] CTD PMID:19053045 NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of MMP9 mRNA] 		CTD PMID:24929186 PMID:29079362 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of MRC1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1,1-dimethylbutyl-1-deoxy-Delta(9)-THC co-treated with F2 protein] results in increased expression of MRC1 protein] CTD PMID:27261088 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA] CTD PMID:26964897 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myh4 myosin heavy chain 4 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Testosterone results in increased expression of MYH4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Testosterone results in increased expression of MYH4 protein] CTD PMID:21374593 NCBI chr10:52,422,148...52,445,296
Ensembl chr10:52,421,951...52,445,294 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA] CTD PMID:18851973 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Myog myogenin multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Testosterone results in increased expression of MYOG mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Testosterone results in increased expression of MYOG protein] CTD PMID:21374593 NCBI chr13:48,297,476...48,300,065
Ensembl chr13:48,297,235...48,300,065 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions 		EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of NFE2L2 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of NFE2L2 protein] 		CTD PMID:29870751 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NFKB1 mRNA] CTD PMID:17407152 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of NLRP3 protein] CTD PMID:37353053 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN3 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Mevinphos results in increased expression of NOS1 protein] CTD PMID:15245872 PMID:17438462 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:44,287,614...44,371,837 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:18851973 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of NQO1 mRNA] CTD PMID:37353053 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 protein] CTD PMID:18787026 NCBI chr  X:54,707,658...54,711,786
Ensembl chr  X:54,707,639...54,712,083 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of NR1H4 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of NR1H4 mRNA]] CTD PMID:27743861 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [cadmium acetate results in increased expression of NR4A1 protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of NR4A1 mRNA] 		CTD PMID:12021184 PMID:15016657 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased expression of NR4A2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased expression of NR4A2 protein] CTD PMID:22188298 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769 		JBrowse link
G Ntf3 neurotrophin 3 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dimaprit results in increased expression of NTF3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of NTF3 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Neurotransmitter Agents results in increased expression of NTF3 protein] CTD PMID:19854260 PMID:21276809 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of PGR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of PGR mRNA] CTD PMID:21220312 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Pink1 PTEN induced kinase 1 decreases expression
multiple interactions 		EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of PINK1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [T-2 Toxin results in increased expression of PINK1 protein] 		CTD PMID:29870751 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Pla2g4a phospholipase A2 group 4A multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA] CTD PMID:18938131 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Pld1 phospholipase D1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]] CTD PMID:17640750 NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245 		JBrowse link
G Plin1 perilipin 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PLIN1 protein] CTD PMID:29288687 NCBI chr 1:143,073,612...143,086,199
Ensembl chr 1:143,074,214...143,086,206 		JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in decreased expression of PLIN2 protein CTD PMID:29288687 NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878 		JBrowse link
G Pln phospholamban decreases phosphorylation EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased phosphorylation of PLN protein CTD PMID:27495954 NCBI chr20:33,166,512...33,182,241
Ensembl chr20:33,172,494...33,182,241 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PNPLA2 protein] CTD PMID:29288687 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359 		JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases expression ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of PNPLA6 mRNA; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of PNPLA6 protein CTD PMID:20380879 NCBI chr12:6,372,284...6,401,632
Ensembl chr12:6,372,293...6,401,631 		JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [diethyl phosphate results in decreased secretion of POMC protein] CTD PMID:35777568 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of PPARGC1A protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA] CTD PMID:16513826 PMID:29288687 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Isoproterenol results in increased phosphorylation of PRKAA1 protein] CTD PMID:19167487 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Atorvastatin results in increased phosphorylation of and results in increased activity of PRKACA protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in decreased expression of PRKACA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in decreased expression of PRKACA protein] 		CTD PMID:19053045 PMID:37353053 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha decreases phosphorylation
multiple interactions 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased phosphorylation of PRKAR2A protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [resveratrol results in increased phosphorylation of PRKAR2A protein] 		CTD PMID:25943029 NCBI chr 8:118,271,608...118,337,332
Ensembl chr 8:118,274,167...118,337,330 		JBrowse link
G Prkca protein kinase C, alpha decreases activity ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of PRKCA protein CTD PMID:16361081 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased expression of PSMB8 protein] CTD PMID:32489702 NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031 		JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased expression of NR4A2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased expression of NR4A2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased phosphorylation of ATF1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased phosphorylation of RELA protein] CTD PMID:22188298 NCBI chr19:41,374,983...41,379,593
Ensembl chr19:41,374,471...41,378,284 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of PTGS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA] 		CTD PMID:17407152 PMID:17640750 PMID:18938131 PMID:19063610 PMID:19147701 More... NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pth parathyroid hormone multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [PTH protein results in decreased uptake of Phosphates] CTD PMID:27432882 NCBI chr 1:176,942,901...176,946,034
Ensembl chr 1:176,943,102...176,946,034 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Dinoprostone co-treated with PTGER1 protein] results in increased phosphorylation of RELA protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADORA2B protein inhibits the reaction [Ethanol results in increased phosphorylation of RELA protein]] 		CTD PMID:22188298 PMID:35143882 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to RELB protein] which binds to CXCL8 promoter]] CTD PMID:17823304 NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420 		JBrowse link
G Rnf187 ring finger protein 187 decreases stability ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased stability of RNF187 protein CTD PMID:25851810 NCBI chr10:44,209,080...44,214,979
Ensembl chr10:44,202,332...44,215,470 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 decreases activity EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of ROCK2 protein CTD PMID:10998351 NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:45,407,965...45,502,771 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 decreases activity ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of RPS6KA3 protein CTD PMID:10998351 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678 		JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 decreases activity EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of RPS6KA5 protein CTD PMID:10998351 PMID:15522277 PMID:18377872 NCBI chr 6:125,558,434...125,736,576
Ensembl chr 6:125,558,434...125,735,856 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases activity
multiple interactions 		ISO
EXP 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of RPS6KB1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [oxyphylla A results in increased phosphorylation of RPS6KB1 protein] 		CTD PMID:10998351 PMID:32489702 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Ryr2 ryanodine receptor 2 decreases phosphorylation EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased phosphorylation of RYR2 protein CTD PMID:27495954 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705 		JBrowse link
G S100b S100 calcium binding protein B multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of S100B protein] CTD PMID:23284918 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of SCARB1 mRNA] CTD PMID:33581290 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Sct secretin multiple interactions
decreases activity 		EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid analog results in increased activity of SCT]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of SCT protein 		CTD PMID:10880878 PMID:22194894 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:205,812,435...205,813,246 		JBrowse link
G Selenot selenoprotein T multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA] CTD PMID:18198219 NCBI chr 2:144,954,324...144,971,375
Ensembl chr 2:144,954,312...144,971,369 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases activity ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of SGK1 protein CTD PMID:10998351 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Si sucrase-isomaltase multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Berberine results in decreased expression of SI mRNA] CTD PMID:20229011 NCBI chr 2:159,804,568...159,884,902
Ensembl chr 2:159,804,568...159,883,934 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with TNF protein] results in decreased expression of SIRT1 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in decreased expression of SIRT1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Resveratrol results in increased expression of SIRT1 protein] CTD PMID:24145604 PMID:25943029 PMID:30409902 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of SLC10A1 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of SLC10A1 mRNA]] CTD PMID:27743861 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 protein] CTD PMID:22645130 PMID:24782323 NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:109,459,630...109,605,249 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased expression of SLC2A3 protein] CTD PMID:24726522 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SLC2A4 mRNA] CTD PMID:17407152 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased stability of SLC2A5 mRNA] CTD PMID:12820898 NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:165,866,172...165,894,038 		JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-((4-chlorophenyl)thio)cyclic-3',5'-AMP affects the splicing of SNAP25 exon]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin affects the splicing of SNAP25 exon] CTD PMID:22684629 NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:144,494,595...144,576,448 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA] CTD PMID:17407152 NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Acetaminophen results in decreased expression of and results in decreased activity of SOD1 protein] CTD PMID:24910983 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of SOD2 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of SOD2 mRNA] CTD PMID:20685861 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] CTD PMID:20453393 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF1 protein] CTD PMID:26125464 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF2 protein] CTD PMID:26125464 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO
EXP 		[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with SB 203580] inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid inhibits the reaction [[CRTC2 protein binds to CREB1 protein modified form] which binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of STAR mRNA] 		CTD PMID:18755854 PMID:18787026 PMID:19282384 PMID:19822634 PMID:23362264 More... NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:22493441 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [5-methyltetrahydrofolate inhibits the reaction [Palmitic Acid results in decreased phosphorylation of STK11 protein]] CTD PMID:26400185 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [KNG1 promotes the reaction [Capsaicin results in increased secretion of TAC1 protein]] CTD PMID:15750287 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Tfap2a transcription factor AP-2 alpha multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [butylbenzyl phthalate affects the localization of TFAP2A protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dibutyl Phthalate affects the localization of TFAP2A protein] CTD PMID:22552774 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in decreased expression of KCNH2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in decreased expression of KCNJ2 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of CDKN1A mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of CDKN2B mRNA] CTD PMID:11576339 PMID:16361081 PMID:22853924 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression 		EXP [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [Nicotine results in increased expression of TH mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of TH mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [HU 211 results in decreased expression of TH mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Nicotine results in increased expression of TH mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of TH mRNA 		CTD PMID:18992715 PMID:29246838 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		[N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with TNF protein] results in decreased expression of SIRT1 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dieldrin results in increased expression of TNF mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Terbutaline inhibits the reaction [Shiga Toxin results in increased expression of TNF protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Terbutaline results in decreased expression of TNF mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of TNF protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNF mRNA] 		CTD PMID:11675405 PMID:17407152 PMID:23284918 PMID:24145604 PMID:25233930 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFAIP6 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA] CTD PMID:21220312 NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796 		JBrowse link
G Tph2 tryptophan hydroxylase 2 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Sertraline results in increased expression of TPH2 mRNA] CTD PMID:11901216 NCBI chr 7:52,571,909...52,676,305
Ensembl chr 7:52,571,911...52,675,639 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:21453681 NCBI chr10:58,349,936...58,375,021
Ensembl chr10:58,340,223...58,375,021 		JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [FSHB protein results in increased phosphorylation of TSC2 protein] CTD PMID:17510244 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in decreased expression of TXN1 protein]] CTD PMID:20453393 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Tyr tyrosinase multiple interactions
decreases activity 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [scoparone results in increased expression of TYR protein]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of TYR protein 		CTD PMID:17049123 PMID:30849679 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857 		JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP
ISO 		N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of UCP1 mRNA]
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of UCP1 protein] 		CTD PMID:12414803 PMID:29288687 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of VASP protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [N(6)-benzoyl-cyclic AMP results in increased phosphorylation of VASP protein] CTD PMID:22363678 PMID:32409581 NCBI chr 1:88,038,026...88,053,783
Ensembl chr 1:88,038,037...88,058,650 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased expression of VEGFA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of VEGFA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] CTD PMID:10788502 PMID:19063610 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vip vasoactive intestinal peptide multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [VIP protein results in increased expression of AQP3 mRNA] CTD PMID:12542607 NCBI chr 1:44,470,232...44,478,561
Ensembl chr 1:44,470,462...44,478,558 		JBrowse link
G Wnt3a Wnt family member 3A multiple interactions ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [WNT3A protein results in increased expression of BMP4 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [WNT3A protein results in increased expression of CREB1 mRNA] CTD PMID:34070360 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression
decreases expression 		ISO N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in increased expression of XIAP protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased expression of XIAP mRNA 		CTD PMID:21255191 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polr2a RNA polymerase II subunit A multiple interactions
decreases phosphorylation 		ISO sodium arsenite inhibits the reaction [N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide results in decreased phosphorylation of POLR2A protein] CTD PMID:8126066 NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO N-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Cyclic AMP co-treated with Verapamil] results in increased expression of STAR protein] CTD PMID:19822634 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
N-butylbenzenesulfonamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 decreases expression EXP N-butylbenzenesulfonamide results in decreased expression of AIF1 mRNA CTD PMID:22824510 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of NR3C1 protein CTD PMID:27633901 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO N-butylbenzenesulfonamide binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
N-tosyl-L-phenylalanyl chloromethyl ketone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of ABCA1 mRNA] CTD PMID:12010990 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions
affects localization 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone affects the localization of AIFM1 protein] CTD PMID:19679660 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein] CTD PMID:17136479 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity EXP Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of ALDH2 protein CTD PMID:11142365 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO
EXP 		Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] CTD PMID:10567916 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [bisphenol A results in decreased expression of APOA1 mRNA]; Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased expression of APOE mRNA]; Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased expression of CETP mRNA]; Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased secretion of APOE protein]; Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased secretion of CETP protein] CTD PMID:22056562 PMID:31842455 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased expression of APOE mRNA]; Tosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased secretion of APOE protein] CTD PMID:22056562 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases cleavage
multiple interactions 		ISO Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of BCL2 protein
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of BCL2 protein] 		CTD PMID:19679660 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression
multiple interactions 		ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC2 protein
Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC2 protein] 		CTD PMID:19679660 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
decreases expression 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC3 protein] CTD PMID:19679660 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions 		ISO Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP3 protein
Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of and results in increased activity of CASP3 protein; TP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP3 protein] 		CTD PMID:12821135 PMID:19679660 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of and results in increased activity of CASP7 protein; TP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP7 protein] CTD PMID:12821135 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:19679660 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases expression 		ISO
EXP 		Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]
Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of CCL2 mRNA
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] 		CTD PMID:12016129 PMID:12846738 PMID:15139008 PMID:16600694 PMID:18706406 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in increased expression of CDKN1A protein CTD PMID:12821135 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA] CTD PMID:17952619 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in decreased localization of CTNNB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin results in increased degradation of and results in decreased activity of CTNNB1 protein] CTD PMID:17030184 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsd cathepsin D increases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in increased expression of CTSD protein CTD PMID:10772776 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLC mRNA CTD PMID:22851183 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLM mRNA CTD PMID:22851183 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions
decreases expression
decreases response to substance 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 protein]
Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 mRNA; Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 protein
HAX1 results in decreased susceptibility to Tosylphenylalanyl Chloromethyl Ketone 		CTD PMID:19679660 NCBI chr 2:177,731,918...177,735,670
Ensembl chr 2:177,731,921...177,735,390 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP
ISO 		Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [resveratrol results in increased expression of HMOX1 protein] 		CTD PMID:15588712 PMID:15965080 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of ICAM1 mRNA CTD PMID:11735124 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein promotes the reaction [RELA protein results in increased phosphorylation of IKBKG protein]] CTD PMID:17136479 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:157,367,639...157,392,757 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA] CTD PMID:12016129 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein promotes the reaction [RELA protein results in increased phosphorylation of IKBKG protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of AKT1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of PDPK1 protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA] 		CTD PMID:12010990 PMID:17136479 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP 		Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased expression of IL6 mRNA]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]] 		CTD PMID:10616907 PMID:10814840 PMID:12016129 PMID:15601679 PMID:17952619 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein] CTD PMID:10739673 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of MMP9 protein CTD PMID:22033475 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects response to substance ISO NFE2L2 protein affects the susceptibility to Tosylphenylalanyl Chloromethyl Ketone CTD PMID:22851183 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP 		Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [platycodin D results in increased activity of [NFKB1 protein binds to RELA protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased activity of [NFKB1 protein binds to RELA protein]]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased localization of [RELA protein co-treated with NFKB1 protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of NFKB1 protein] 		CTD PMID:10416616 PMID:10616907 PMID:11094054 PMID:12016129 PMID:16631160 More... NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
decreases degradation 		ISO
EXP 		[Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of RELA protein] inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of RELA protein] inhibits the reaction [TGFB1 protein results in increased phosphorylation of NFKBIA protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased degradation of NFKBIA protein]
Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of NFKBIA protein
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]
Tosylphenylalanyl Chloromethyl Ketone results in decreased degradation of NFKBIA protein 		CTD PMID:9580637 PMID:10381628 PMID:10921504 PMID:12574206 PMID:15687330 More... NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions
decreases phosphorylation 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of NFKBIB protein]; Cysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of NFKBIB protein] CTD PMID:10381628 NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] CTD PMID:15601679 PMID:18449507 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in increased expression of NQO1 mRNA CTD PMID:22851183 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions EXP Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [NRG1 protein results in increased transport of Glucose] CTD PMID:14711829 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein] CTD PMID:19679660 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pde5a phosphodiesterase 5A decreases expression EXP Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of PDE5A mRNA CTD PMID:12466227 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 multiple interactions
decreases activity 		ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased phosphorylation of PDPK1 protein]
Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of PDPK1 protein 		CTD PMID:17136479 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of PLAU protein CTD PMID:10467400 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA] CTD PMID:9580637 PMID:17944529 PMID:18449507 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects activity
decreases activity 		ISO
EXP 		[Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of RELA protein] inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of RELA protein] inhibits the reaction [TGFB1 protein results in increased phosphorylation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL17A protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein promotes the reaction [RELA protein results in increased phosphorylation of IKBKG protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1B protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [platycodin D results in increased activity of [NFKB1 protein binds to RELA protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased transport of RELA protein]
Tosylphenylalanyl Chloromethyl Ketone affects the activity of RELA protein
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased localization of [RELA protein co-treated with NFKB1 protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of RELA protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased activity of [NFKB1 protein binds to RELA protein]] 		CTD PMID:10416616 PMID:10467400 PMID:10616907 PMID:10640779 PMID:11094054 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of SCARB1 mRNA] CTD PMID:12010990 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of SOD2 protein] CTD PMID:7476933 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:10616907 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Tcf4 transcription factor 4 multiple interactions ISO Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Nitroglycerin inhibits the reaction [CTNNB1 protein binds to TCF4 protein]] CTD PMID:17030184 NCBI chr18:65,216,840...65,563,186
Ensembl chr18:65,216,849...65,558,401 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of RELA protein] inhibits the reaction [TGFB1 protein results in increased phosphorylation of NFKBIA protein] CTD PMID:16288038 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Tosylphenylalanyl Chloromethyl Ketone results in decreased activity of RELA protein] inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased activity of RELA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased transport of RELA protein]
Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [TNF protein results in increased expression of RELA protein] 		CTD PMID:7476933 PMID:9580637 PMID:10416616 PMID:10616907 PMID:10640779 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
increases response to substance 		ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of and results in increased activity of TP53 protein; TP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP3 protein]; TP53 protein promotes the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased activity of CASP7 protein]
Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of TRP53 protein
TP53 protein results in increased susceptibility to Tosylphenylalanyl Chloromethyl Ketone 		CTD PMID:11536013 PMID:12821135 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of VCAM1 mRNA CTD PMID:11735124 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
increases cleavage 		ISO Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of XIAP protein] CTD PMID:19679660 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
naratriptan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1b 5-hydroxytryptamine receptor 1B affects binding ISO naratriptan binds to HTR1B protein CTD PMID:9170336 NCBI chr 8:91,395,405...91,414,815
Ensembl chr 8:91,052,432...91,418,583 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D affects binding ISO naratriptan binds to HTR1D protein CTD PMID:9170336 NCBI chr 5:153,939,735...153,960,012
Ensembl chr 5:153,939,516...153,960,012 		JBrowse link
nimesulide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase decreases expression EXP nimesulide results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525 		JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP nimesulide results in decreased expression of ABAT mRNA CTD PMID:24136188 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression EXP nimesulide results in decreased expression of ABCA1 mRNA CTD PMID:24136188 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473 		JBrowse link
G Abca8a ATP-binding cassette, subfamily A (ABC1), member 8a decreases expression EXP nimesulide results in decreased expression of ABCA8A mRNA CTD PMID:24136188 NCBI chr10:95,501,798...95,571,770
Ensembl chr10:95,501,798...95,571,873 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
increases expression 		ISO nimesulide results in decreased expression of ABCB1 protein
nimesulide results in increased expression of ABCB1 mRNA 		CTD PMID:21745461 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression EXP nimesulide results in increased expression of ABCB6 mRNA CTD PMID:24136188 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO nimesulide results in increased expression of ABCC1 mRNA CTD PMID:21745461 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP nimesulide results in increased expression of ABCC2 mRNA CTD PMID:24136188 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP nimesulide results in increased expression of ABCC3 mRNA CTD PMID:24136188 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression EXP nimesulide results in increased expression of ABCE1 mRNA CTD PMID:24136188 NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity
decreases expression 		ISO nimesulide results in decreased activity of ABCG2 protein
nimesulide results in decreased expression of ABCG2 protein 		CTD PMID:18581209 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abcg3l2 ATP-binding cassette, subfamily G (WHITE), member 3-like 2 decreases expression EXP nimesulide results in decreased expression of ABCG3L2 mRNA CTD PMID:24136188 NCBI chr14:4,798,053...4,847,424
Ensembl chr14:4,798,053...4,838,117 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP nimesulide results in increased expression of ACAA1 mRNA CTD PMID:24136188 NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP nimesulide results in increased expression of ACAA2 mRNA CTD PMID:24136188 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP nimesulide results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO
EXP 		nimesulide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Acly ATP citrate lyase decreases expression EXP nimesulide results in decreased expression of ACLY mRNA CTD PMID:24136188 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Aco1 aconitase 1 increases expression EXP nimesulide results in increased expression of ACO1 mRNA CTD PMID:24136188 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600 		JBrowse link
G Aco2 aconitase 2 increases expression EXP nimesulide results in increased expression of ACO2 mRNA CTD PMID:24136188 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP nimesulide results in increased expression of ACOT2 mRNA CTD PMID:24136188 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 increases expression EXP nimesulide results in increased expression of ACOT7 mRNA CTD PMID:24136188 NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033 		JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl decreases expression EXP nimesulide results in decreased expression of ACOX3 mRNA CTD PMID:24136188 NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881 		JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP nimesulide results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression EXP nimesulide results in decreased expression of ACSL1 mRNA CTD PMID:24136188 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP nimesulide results in increased expression of ACSL4 mRNA CTD PMID:24136188 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP nimesulide results in decreased expression of ACSL5 mRNA CTD PMID:24136188 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 decreases expression EXP nimesulide results in decreased expression of ADAMTS7 mRNA CTD PMID:24136188 NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132 		JBrowse link
G Adck5 aarF domain containing kinase 5 increases expression EXP nimesulide results in increased expression of ADCK5 mRNA CTD PMID:24136188 NCBI chr 7:110,182,275...110,200,088
Ensembl chr 7:110,181,981...110,200,088 		JBrowse link
G Add1 adducin 1 increases expression EXP nimesulide results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 decreases expression EXP nimesulide results in decreased expression of ADGRL2 mRNA CTD PMID:24136188 NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP nimesulide results in decreased expression of ADHFE1 mRNA CTD PMID:24136188 NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835 		JBrowse link
G Adipor2 adiponectin receptor 2 decreases expression EXP nimesulide results in decreased expression of ADIPOR2 mRNA CTD PMID:24136188 NCBI chr 4:154,195,440...154,261,141
Ensembl chr 4:154,172,567...154,231,666 		JBrowse link
G Adprm ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent increases expression EXP nimesulide results in increased expression of ADPRM mRNA CTD PMID:24136188 NCBI chr10:52,231,085...52,243,637
Ensembl chr10:52,230,233...52,243,569 		JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor increases expression EXP nimesulide results in increased expression of ADRM1 mRNA CTD PMID:24136188 NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483 		JBrowse link
G Adsl adenylosuccinate lyase increases expression EXP nimesulide results in increased expression of ADSL mRNA CTD PMID:24136188 NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872 		JBrowse link
G Afm afamin decreases expression EXP nimesulide results in decreased expression of AFM mRNA CTD PMID:24136188 NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039 		JBrowse link
G Agt angiotensinogen decreases activity ISO nimesulide results in decreased activity of AGT CTD PMID:12065685 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase decreases expression EXP nimesulide results in decreased expression of AGXT mRNA CTD PMID:24136188 NCBI chr 9:101,122,793...101,132,746
Ensembl chr 9:101,122,793...101,132,745 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression EXP nimesulide results in decreased expression of AGXT2 mRNA CTD PMID:24136188 NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:61,063,419...61,105,090 		JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression EXP nimesulide results in increased expression of AHSA1 mRNA CTD PMID:24136188 NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP nimesulide results in decreased expression of AIF1 mRNA CTD PMID:24136188 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339 		JBrowse link
G Aig1 androgen-induced 1 increases expression EXP nimesulide results in increased expression of AIG1 mRNA CTD PMID:24136188 NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155 		JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 increases expression EXP nimesulide results in increased expression of AIMP2 mRNA CTD PMID:24136188 NCBI chr12:15,814,854...15,824,432
Ensembl chr12:15,814,878...15,824,431 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression EXP nimesulide results in decreased expression of AK4 mRNA CTD PMID:24136188 NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP nimesulide results in increased expression of AKR1A1 mRNA CTD PMID:24136188 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP nimesulide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP nimesulide results in increased expression of AKR7A3 mRNA CTD PMID:24136188 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153 		JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression EXP nimesulide results in increased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP nimesulide results in increased expression of ALAS1 mRNA CTD PMID:24136188 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642 		JBrowse link
G Alcam activated leukocyte cell adhesion molecule decreases expression EXP nimesulide results in decreased expression of ALCAM mRNA CTD PMID:24136188 NCBI chr11:61,804,932...62,005,250
Ensembl chr11:61,805,049...62,006,876 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP nimesulide results in increased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP nimesulide results in increased expression of ALDH1A7 mRNA CTD PMID:24136188 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP nimesulide results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression EXP nimesulide results in increased expression of ALG12 mRNA CTD PMID:24136188 NCBI chr 7:121,774,796...121,789,175
Ensembl chr 7:121,768,234...121,788,983 		JBrowse link
G Alg14 ALG14, UDP-N-acetylglucosaminyltransferase subunit increases expression EXP nimesulide results in increased expression of ALG14 mRNA CTD PMID:24136188 NCBI chr 2:212,053,008...212,130,136
Ensembl chr 2:212,044,969...212,130,140 		JBrowse link
G Amy2a3 amylase 2a3 decreases expression EXP nimesulide results in decreased expression of AMY1A mRNA CTD PMID:24136188 NCBI chr 2:204,005,840...204,014,412
Ensembl chr 2:204,005,840...204,014,413 		JBrowse link
G Ang angiogenin decreases expression EXP nimesulide results in decreased expression of ANG mRNA CTD PMID:24136188 NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP nimesulide results in decreased expression of ANGPTL3 mRNA CTD PMID:24136188 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO nimesulide results in increased expression of ANGPTL4 mRNA CTD PMID:19415698 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP nimesulide results in decreased expression of ANKH mRNA CTD PMID:24136188 NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699 		JBrowse link
G Ankrd24 ankyrin repeat domain 24 increases expression EXP nimesulide results in increased expression of ANKRD24 mRNA CTD PMID:24136188 NCBI chr 7:8,712,720...8,731,910
Ensembl chr 7:8,712,722...8,731,910 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP nimesulide results in decreased expression of ANPEP mRNA CTD PMID:24136188 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101 		JBrowse link
G Anxa3 annexin A3 decreases expression EXP nimesulide results in decreased expression of ANXA3 mRNA CTD PMID:24136188 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Anxa4 annexin A4 increases expression EXP nimesulide results in increased expression of ANXA4 mRNA CTD PMID:24136188 NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:120,741,750...120,798,513 		JBrowse link
G Anxa5 annexin A5 decreases expression EXP nimesulide results in decreased expression of ANXA5 mRNA CTD PMID:24136188 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Anxa7 annexin A7 increases expression EXP nimesulide results in increased expression of ANXA7 mRNA CTD PMID:24136188 NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891 		JBrowse link
G Aopep aminopeptidase O decreases expression EXP nimesulide results in decreased expression of AOPEP mRNA CTD PMID:24136188 NCBI chr17:1,817,001...2,133,008
Ensembl chr17:1,817,001...2,133,104 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP nimesulide results in increased expression of APEX1 mRNA CTD PMID:24136188 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP nimesulide results in decreased expression of APLP2 mRNA CTD PMID:24136188 NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031 		JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP nimesulide results in decreased expression of APMAP mRNA CTD PMID:24136188 NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726 		JBrowse link
G Apoa5 apolipoprotein A5 decreases expression EXP nimesulide results in decreased expression of APOA5 mRNA CTD PMID:24136188 NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO nimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein]; nimesulide inhibits the reaction [APOE results in increased abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:14966570 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Apol2 apolipoprotein L2 decreases expression EXP nimesulide results in decreased expression of APOL3 mRNA CTD PMID:24136188 NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:111,211,893...111,217,223 		JBrowse link
G Apol9a-Apol7a Apol9a-Apol7a readthrough decreases expression EXP nimesulide results in decreased expression of APOL7B mRNA CTD PMID:24136188 NCBI chr 7:111,011,645...111,019,326
Ensembl chr 7:111,011,645...111,017,084 		JBrowse link
G Apon apolipoprotein N increases expression EXP nimesulide results in increased expression of APON mRNA CTD PMID:24136188 NCBI chr 7:1,271,514...1,272,917
Ensembl chr 7:1,271,515...1,272,917 		JBrowse link
G Aprt adenine phosphoribosyl transferase increases expression EXP nimesulide results in increased expression of APRT mRNA CTD PMID:24136188 NCBI chr19:67,534,737...67,537,027 JBrowse link
G Aqp8 aquaporin 8 increases expression EXP nimesulide results in increased expression of AQP8 mRNA CTD PMID:24136188 NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242 		JBrowse link
G Areg amphiregulin multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of AREG mRNA]; nimesulide inhibits the reaction [LHB results in increased expression of AREG protein] CTD PMID:16888076 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP nimesulide results in decreased expression of ARHGAP24 mRNA CTD PMID:24136188 NCBI chr14:7,105,200...7,488,437
Ensembl chr14:7,105,200...7,528,950 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression EXP nimesulide results in decreased expression of ARHGDIB mRNA CTD PMID:24136188 NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068 		JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression EXP nimesulide results in decreased expression of ARHGEF19 mRNA CTD PMID:24136188 NCBI chr 5:158,818,840...158,837,196
Ensembl chr 5:158,818,932...158,837,196 		JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP nimesulide results in increased expression of ARPC5L mRNA CTD PMID:24136188 NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240
Ensembl chr 9:43,169,462...43,177,240 		JBrowse link
G Arpin actin-related protein 2/3 complex inhibitor increases expression EXP nimesulide results in increased expression of ARPIN mRNA CTD PMID:24136188 NCBI chr 1:143,273,590...143,282,426
Ensembl chr 1:143,273,590...143,282,532 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP nimesulide results in increased expression of ARPP19 mRNA CTD PMID:24136188 NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385 		JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 decreases expression EXP nimesulide results in decreased expression of ASAP2 mRNA CTD PMID:24136188 NCBI chr 6:46,386,605...46,549,669
Ensembl chr 6:46,386,605...46,549,669 		JBrowse link
G Asgr2 asialoglycoprotein receptor 2 decreases expression EXP nimesulide results in decreased expression of ASGR2 mRNA CTD PMID:24136188 NCBI chr10:55,320,082...55,333,294
Ensembl chr10:55,320,091...55,333,263 		JBrowse link
G Aspg asparaginase decreases expression EXP nimesulide results in decreased expression of ASPG mRNA CTD PMID:24136188 NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417 		JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP nimesulide results in increased expression of ATF4 mRNA CTD PMID:24136188 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP nimesulide results in increased expression of ATIC mRNA CTD PMID:24136188 NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756 		JBrowse link
G Atl2 atlastin GTPase 2 increases expression EXP nimesulide results in increased expression of ATL2 mRNA CTD PMID:24136188 NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320 		JBrowse link
G Atosa atos homolog A decreases expression EXP nimesulide results in decreased expression of ATOSA mRNA CTD PMID:24136188 NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP nimesulide results in decreased expression of ATP1B1 mRNA CTD PMID:24136188 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP nimesulide results in increased expression of ATP5IF1 mRNA CTD PMID:24136188 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP nimesulide results in increased expression of ATP5MC1 mRNA CTD PMID:24136188 NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression EXP nimesulide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B increases expression EXP nimesulide results in increased expression of ATP6V0B mRNA CTD PMID:24136188 NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression EXP nimesulide results in increased expression of ATP6V0E1 mRNA CTD PMID:24136188 NCBI chr10:16,984,084...17,007,156
Ensembl chr10:16,984,084...17,028,858 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression EXP nimesulide results in increased expression of ATP6V0E2 mRNA CTD PMID:24136188 NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F increases expression EXP nimesulide results in increased expression of ATP6V1F mRNA CTD PMID:24136188 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 increases expression EXP nimesulide results in increased expression of ATP6V1G1 mRNA CTD PMID:24136188 NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930 		JBrowse link
G Atrn attractin decreases expression EXP nimesulide results in decreased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360 		JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor increases expression EXP nimesulide results in increased expression of AUP1 mRNA CTD PMID:24136188 NCBI chr 4:117,118,035...117,121,063
Ensembl chr 4:117,117,999...117,121,061 		JBrowse link
G Aven apoptosis and caspase activation inhibitor increases expression EXP nimesulide results in increased expression of AVEN mRNA CTD PMID:24136188 NCBI chr 3:119,753,395...119,886,009
Ensembl chr 3:119,872,661...119,886,008 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP nimesulide results in decreased expression of AVPR1A mRNA CTD PMID:24136188 NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837 		JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression EXP nimesulide results in decreased expression of AXL mRNA CTD PMID:24136188 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G B2m beta-2 microglobulin decreases expression EXP nimesulide results in decreased expression of B2M mRNA CTD PMID:24136188 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
decreases response to substance 		ISO
EXP 		nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
BAK1 results in decreased susceptibility to nimesulide 		CTD PMID:18349538 PMID:21745461 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 increases expression EXP nimesulide results in increased expression of BANF1 mRNA CTD PMID:24136188 NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein] CTD PMID:21745461 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP nimesulide results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression EXP nimesulide results in decreased expression of BCAR1 mRNA CTD PMID:24136188 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein increases expression EXP nimesulide results in increased expression of BCCIP mRNA CTD PMID:24136188 NCBI chr 1:197,942,535...197,954,948
Ensembl chr 1:197,942,190...197,956,378 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
affects localization 		ISO
EXP 		nimesulide results in decreased expression of BCL2 mRNA; nimesulide results in decreased expression of BCL2 protein
nimesulide affects the localization of BCL2 protein 		CTD PMID:18564172 PMID:19772912 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone increases expression EXP nimesulide results in increased expression of BCS1L mRNA CTD PMID:24136188 NCBI chr 9:83,614,045...83,618,052
Ensembl chr 9:83,613,975...83,618,257 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression EXP nimesulide results in decreased expression of BDH1 mRNA CTD PMID:24136188 NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636 		JBrowse link
G Bet1 Bet1 golgi vesicular membrane trafficking protein increases expression EXP nimesulide results in increased expression of BET1 mRNA CTD PMID:24136188 NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164 		JBrowse link
G Bgn biglycan decreases expression EXP nimesulide results in decreased expression of BGN mRNA CTD PMID:24136188 NCBI chr  X:156,348,633...156,360,797
Ensembl chr  X:156,348,615...156,360,799 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP nimesulide results in decreased expression of BHLHE40 mRNA CTD PMID:24136188 NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP nimesulide results in decreased expression of BHMT mRNA CTD PMID:24136188 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715 		JBrowse link
G Bhmt2 betaine-homocysteine S-methyltransferase 2 decreases expression EXP nimesulide results in decreased expression of BHMT2 mRNA CTD PMID:24136188 NCBI chr 2:26,630,502...26,647,450
Ensembl chr 2:26,630,510...26,651,326 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of BID protein]; nimesulide results in increased cleavage of and results in increased activity of BID protein CTD PMID:19360361 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
decreases expression 		ISO nimesulide results in decreased expression of BIRC5 protein
Nimesulide decreases expression of BIRC5 protein in esophagus squamous epithelium 		CTD
RGD		 PMID:16969492 PMID:25724470 RGD:127285656 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155 		JBrowse link
G Blvrb biliverdin reductase B increases expression EXP nimesulide results in increased expression of BLVRB mRNA CTD PMID:24136188 NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225 		JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression EXP nimesulide results in decreased expression of BMP1 mRNA CTD PMID:24136188 NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO nimesulide results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP nimesulide results in increased expression of BNIP3 mRNA CTD PMID:24136188 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP nimesulide results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Bola1 bolA family member 1 increases expression EXP nimesulide results in increased expression of BOLA1 mRNA CTD PMID:24136188 NCBI chr 2:186,447,386...186,448,402
Ensembl chr 2:186,443,583...186,501,358 		JBrowse link
G Bola2-ps4 bolA family member 2, pseudogene 4 increases expression EXP nimesulide results in increased expression of BOLA2-PS4 mRNA CTD PMID:24136188 NCBI chr 3:173,691,781...173,692,136 JBrowse link
G Bola3 bolA family member 3 increases expression EXP nimesulide results in increased expression of BOLA3 mRNA CTD PMID:24136188 NCBI chr 4:117,411,044...117,420,491
Ensembl chr 4:117,410,680...117,420,491 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression EXP nimesulide results in increased expression of BOP1 mRNA CTD PMID:24136188 NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP nimesulide results in decreased expression of BTG1 mRNA CTD PMID:24136188 NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406 		JBrowse link
G Bysl bystin-like increases expression EXP nimesulide results in increased expression of BYSL mRNA CTD PMID:24136188 NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900 		JBrowse link
G C10h17orf58 similar to human chromosome 17 open reading frame 58 increases expression EXP nimesulide results in increased expression of C10H17ORF58 mRNA CTD PMID:24136188 NCBI chr10:92,472,779...92,477,330
Ensembl chr10:92,471,934...92,477,330 		JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 increases expression EXP nimesulide results in increased expression of C10H5ORF15 mRNA CTD PMID:24136188 NCBI chr10:37,064,889...37,077,493
Ensembl chr10:37,064,728...37,077,493 		JBrowse link
G C18h18orf32 similar to human chromosome 18 open reading frame 32 increases expression EXP nimesulide results in increased expression of C18H18ORF32 mRNA CTD PMID:24136188 NCBI chr18:70,861,434...70,869,983
Ensembl chr18:70,861,435...70,869,983 		JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 increases expression EXP nimesulide results in increased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:122,243,736...122,248,217
Ensembl chr  X:122,234,454...122,248,422 		JBrowse link
G C1qa complement C1q A chain decreases expression EXP nimesulide results in decreased expression of C1QA mRNA CTD PMID:24136188 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732 		JBrowse link
G C1qb complement C1q B chain multiple interactions
decreases expression 		ISO
EXP 		nimesulide inhibits the reaction [PTGS2 results in increased expression of C1QB mRNA]
nimesulide results in decreased expression of C1QB mRNA 		CTD PMID:11810182 PMID:24136188 NCBI chr 5:154,402,276...154,407,827
Ensembl chr 5:154,402,279...154,407,840 		JBrowse link
G C1qbp complement C1q binding protein increases expression EXP nimesulide results in increased expression of C1QBP mRNA CTD PMID:24136188 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235 		JBrowse link
G C1qc complement C1q C chain decreases expression EXP nimesulide results in decreased expression of C1QC mRNA CTD PMID:24136188 NCBI chr 5:154,410,845...154,414,208
Ensembl chr 5:154,410,848...154,414,468 		JBrowse link
G C1s complement C1s decreases expression EXP nimesulide results in decreased expression of C1S mRNA CTD PMID:24136188 NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736 		JBrowse link
G C20h6orf89 similar to human chromosome 6 open reading frame 89 increases expression EXP nimesulide results in increased expression of C20H6ORF89 mRNA CTD PMID:24136188 NCBI chr20:7,324,105...7,368,482
Ensembl chr20:7,324,129...7,363,666 		JBrowse link
G C6 complement C6 decreases expression EXP nimesulide results in decreased expression of C6 mRNA CTD PMID:24136188 NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120 		JBrowse link
G C8a complement C8 alpha chain decreases expression EXP nimesulide results in decreased expression of C8A mRNA CTD PMID:24136188 NCBI chr 5:124,812,131...124,866,631
Ensembl chr 5:124,812,131...124,866,710 		JBrowse link
G C8b complement C8 beta chain decreases expression EXP nimesulide results in decreased expression of C8B mRNA CTD PMID:24136188 NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516 		JBrowse link
G C8h11orf54 similar to human chromosome 11 open reading frame 54 increases expression EXP nimesulide results in increased expression of C8H11ORF54 mRNA CTD PMID:24136188 NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811 		JBrowse link
G C9 complement C9 decreases expression EXP nimesulide results in decreased expression of C9 mRNA CTD PMID:24136188 NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752 		JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP nimesulide results in decreased expression of CAR3 mRNA CTD PMID:24136188 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Ca8 carbonic anhydrase 8 increases expression EXP nimesulide results in increased expression of CAR8 mRNA CTD PMID:24136188 NCBI chr 5:26,102,767...26,199,819
Ensembl chr 5:26,102,813...26,199,796 		JBrowse link
G Cacybp calcyclin binding protein increases expression EXP nimesulide results in increased expression of CACYBP mRNA CTD PMID:24136188 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505 		JBrowse link
G Calm2 calmodulin 2 decreases expression EXP nimesulide results in decreased expression of CALM2 mRNA CTD PMID:24136188 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Canx calnexin increases expression EXP nimesulide results in increased expression of CANX mRNA CTD PMID:24136188 NCBI chr10:35,124,941...35,157,954
Ensembl chr10:35,124,941...35,157,857 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 decreases expression EXP nimesulide results in decreased expression of CAP1 mRNA CTD PMID:24136188 NCBI chr 5:140,427,265...140,507,678
Ensembl chr 5:140,427,269...140,453,470 		JBrowse link
G Capn2 calpain 2 decreases expression EXP nimesulide results in decreased expression of CAPN2 mRNA CTD PMID:24136188 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP nimesulide results in decreased expression of CARHSP1 mRNA CTD PMID:24136188 NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity 		ISO
EXP 		benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP3 protein
Nimesulide increases expression of CASP3 protein in esophagus squamous epithelium
nimesulide results in increased cleavage of CASP3 protein
nimesulide results in increased expression of CASP3 mRNA
nimesulide results in increased activity of CASP3 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP3 protein]
nimesulide results in increased expression of CASP3 mRNA; nimesulide results in increased expression of CASP3 protein 		CTD
RGD		 PMID:11296547 PMID:19360361 PMID:19772912 PMID:21176579 PMID:21745461 More... RGD:127285656 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; nimesulide results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:19360361 PMID:21745461 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity 		ISO
EXP 		benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [nimesulide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; nimesulide results in increased cleavage of and results in increased activity of CASP9 protein
nimesulide results in increased cleavage of CASP9 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]; Silymarin inhibits the reaction [nimesulide results in increased cleavage of CASP9 protein]
nimesulide results in increased activity of CASP9 protein 		CTD PMID:19360361 PMID:19772912 PMID:21745461 PMID:22509279 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions 		ISO
EXP 		nimesulide results in decreased expression of CAT protein
nimesulide results in decreased activity of CAT; nimesulide results in decreased activity of CAT protein
nimesulide inhibits the reaction [Quinolinic Acid results in decreased expression of CAT protein] 		CTD PMID:17147060 PMID:17274466 PMID:18848576 PMID:20043943 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 increases expression ISO nimesulide results in increased expression of CAV1 protein CTD PMID:18848576 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP nimesulide results in increased expression of CAVIN3 mRNA CTD PMID:24136188 NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981 		JBrowse link
G Cbr1 carbonyl reductase 1 increases expression EXP nimesulide results in increased expression of CBR1 mRNA CTD PMID:24136188 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104 		JBrowse link
G Ccdc107 coiled-coil domain containing 107 decreases expression EXP nimesulide results in decreased expression of CCDC107 mRNA CTD PMID:24136188 NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:62,544,714...62,548,709 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases expression EXP nimesulide results in increased expression of CCDC6 mRNA CTD PMID:24136188 NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression EXP nimesulide results in decreased expression of CCDC80 mRNA CTD PMID:24136188 NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions 		ISO
EXP 		nimesulide results in decreased expression of CCL2 protein
[nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CCL2 mRNA
nimesulide inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; nimesulide inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein] 		CTD PMID:17380299 PMID:20039930 PMID:22561872 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression EXP nimesulide results in decreased expression of CCL6 mRNA CTD PMID:24136188 NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO nimesulide inhibits the reaction [APOE results in decreased expression of CCNA2 protein] CTD PMID:14966570 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb2 cyclin B2 decreases expression EXP nimesulide results in decreased expression of CCNB2 mRNA CTD PMID:24136188 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression 		ISO
EXP 		nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA]
nimesulide results in decreased expression of CCND1 mRNA 		CTD PMID:20043093 PMID:24136188 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression EXP nimesulide results in increased expression of CCT2 mRNA CTD PMID:24136188 NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP nimesulide results in increased expression of CCT3 mRNA CTD PMID:24136188 NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression EXP nimesulide results in increased expression of CCT4 mRNA CTD PMID:24136188 NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression EXP nimesulide results in increased expression of CCT5 mRNA CTD PMID:24136188 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression EXP nimesulide results in increased expression of CCT6A mRNA CTD PMID:24136188 NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression EXP nimesulide results in increased expression of CCT7 mRNA CTD PMID:24136188 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression EXP nimesulide results in increased expression of CCT8 mRNA CTD PMID:24136188 NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328 		JBrowse link
G Cd14 CD14 molecule decreases expression EXP nimesulide results in decreased expression of CD14 mRNA CTD PMID:24136188 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd164 CD164 molecule decreases expression EXP nimesulide results in decreased expression of CD164 mRNA CTD PMID:24136188 NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649 		JBrowse link
G Cd59b CD59b molecule decreases expression EXP nimesulide results in decreased expression of CD59 mRNA CTD PMID:24136188 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Cd5l Cd5 molecule-like decreases expression EXP nimesulide results in decreased expression of CD5L mRNA CTD PMID:24136188 NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:175,088,884...175,099,926 		JBrowse link
G Cd68 Cd68 molecule decreases expression EXP nimesulide results in decreased expression of CD68 mRNA CTD PMID:24136188 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cd74 CD74 molecule decreases expression EXP nimesulide results in decreased expression of CD74 mRNA CTD PMID:24136188 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Cd81 Cd81 molecule decreases expression EXP nimesulide results in decreased expression of CD81 mRNA CTD PMID:24136188 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092 		JBrowse link
G Cd82 Cd82 molecule decreases expression EXP nimesulide results in decreased expression of CD82 mRNA CTD PMID:24136188 NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP nimesulide results in decreased expression of CDC20 mRNA CTD PMID:24136188 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:137,251,596...137,255,799 		JBrowse link
G Cdc5l cell division cycle 5-like decreases expression EXP nimesulide results in decreased expression of CDC5L mRNA CTD PMID:24136188 NCBI chr 9:23,062,397...23,100,901
Ensembl chr 9:23,062,205...23,100,899 		JBrowse link
G Cdh17 cadherin 17 increases expression EXP nimesulide results in increased expression of CDH17 mRNA CTD PMID:24136188 NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:30,060,090...30,112,226 		JBrowse link
G Cdh2 cadherin 2 decreases expression EXP nimesulide results in decreased expression of CDH2 mRNA CTD PMID:24136188 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP nimesulide results in decreased expression of CDK1 mRNA CTD PMID:24136188 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions 		ISO nimesulide results in increased expression of CDKN1A mRNA; nimesulide results in increased expression of CDKN1A protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased expression of CDKN1A mRNA] 		CTD PMID:14567460 PMID:16376453 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO nimesulide results in increased expression of CDKN1B; nimesulide results in increased expression of CDKN1B protein CTD PMID:12717830 PMID:14567460 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO nimesulide inhibits the reaction [PTGS2 results in decreased expression of CDKN2C mRNA] CTD PMID:11961048 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP nimesulide results in decreased expression of CDKN3 mRNA CTD PMID:24136188 NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP nimesulide results in decreased expression of CDO1 mRNA CTD PMID:24136188 NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression EXP nimesulide results in decreased expression of CEACAM1 mRNA CTD PMID:24136188 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 decreases expression EXP nimesulide results in decreased expression of CEACAM10 mRNA CTD PMID:24136188 NCBI chr 1:89,504,555...89,510,831
Ensembl chr 1:89,504,555...89,510,831 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO
EXP 		nimesulide promotes the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CEBPA protein]
nimesulide inhibits the reaction [Dietary Fats results in decreased expression of CEBPA mRNA] 		CTD PMID:19247274 PMID:22107987 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cep170 centrosomal protein 170 decreases expression EXP nimesulide results in decreased expression of CEP170 mRNA CTD PMID:24136188 NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990 		JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP nimesulide results in increased expression of CES2 mRNA CTD PMID:24136188 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752 		JBrowse link
G Cfh complement factor H decreases expression EXP nimesulide results in decreased expression of CFH mRNA CTD PMID:24136188 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Cfl1 cofilin 1 increases expression EXP nimesulide results in increased expression of CFL1 mRNA CTD PMID:24136188 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Cgn cingulin decreases expression EXP nimesulide results in decreased expression of CGN mRNA CTD PMID:24136188 NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635 		JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP nimesulide results in increased expression of CGRRF1 mRNA CTD PMID:24136188 NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811 		JBrowse link
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 increases expression EXP nimesulide results in increased expression of CHCHD1 mRNA CTD PMID:24136188 NCBI chr15:3,641,973...3,643,155
Ensembl chr15:3,641,981...3,643,155 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 increases expression EXP nimesulide results in increased expression of CHCHD2 mRNA CTD PMID:24136188 NCBI chr12:32,464,847...32,470,871
Ensembl chr12:32,464,824...32,470,871 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP nimesulide results in increased expression of CHCHD6 mRNA CTD PMID:24136188 NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421 		JBrowse link
G Chid1 chitinase domain containing 1 increases expression EXP nimesulide results in increased expression of CHID1 mRNA CTD PMID:24136188 NCBI chr 1:206,024,059...206,059,259
Ensembl chr 1:205,998,801...206,059,227 		JBrowse link
G Chka choline kinase alpha decreases expression EXP nimesulide results in decreased expression of CHKA mRNA CTD PMID:24136188 NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression EXP nimesulide results in increased expression of CHORDC1 mRNA CTD PMID:24136188 NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696 		JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression EXP nimesulide results in increased expression of CHPT1 mRNA CTD PMID:24136188 NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521 		JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression EXP nimesulide results in increased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:106,901,841...106,905,441 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression EXP nimesulide results in increased expression of CHUK mRNA CTD PMID:24136188 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Churc1 churchill domain containing 1 increases expression EXP nimesulide results in increased expression of CHURC1 mRNA CTD PMID:24136188 NCBI chr 6:101,203,778...101,218,364
Ensembl chr 6:101,203,841...101,237,748 		JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A increases expression EXP nimesulide results in increased expression of CIAO2A mRNA CTD PMID:24136188 NCBI chr 8:75,565,620...75,577,542
Ensembl chr 8:75,565,567...75,577,541 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression EXP nimesulide results in increased expression of CIAPIN1 mRNA CTD PMID:24136188 NCBI chr19:10,185,955...10,199,120
Ensembl chr19:10,182,088...10,201,495 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP nimesulide results in increased expression of CIDEA mRNA CTD PMID:24136188 NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382 		JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP nimesulide results in increased expression of CISD2 mRNA CTD PMID:24136188 NCBI chr 2:226,502,517...226,527,325
Ensembl chr 2:226,502,517...226,540,080 		JBrowse link
G Cisd3 CDGSH iron sulfur domain 3 increases expression EXP nimesulide results in increased expression of CISD3 mRNA CTD PMID:24136188 NCBI chr10:83,175,708...83,178,739
Ensembl chr10:83,175,568...83,178,751 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP nimesulide results in decreased expression of CITED2 mRNA CTD PMID:24136188 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression EXP nimesulide results in increased expression of CKS1B mRNA CTD PMID:24136188 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP nimesulide results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519 		JBrowse link
G Cldnd1 claudin domain containing 1 increases expression EXP nimesulide results in increased expression of CLDND1 mRNA CTD PMID:24136188 NCBI chr11:55,352,321...55,358,779
Ensembl chr11:55,352,321...55,358,907 		JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP nimesulide results in decreased expression of CLEC4F mRNA CTD PMID:24136188 NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression EXP nimesulide results in increased expression of CLIP1 mRNA CTD PMID:24136188 NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression EXP nimesulide results in increased expression of CLPP mRNA CTD PMID:24136188 NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X decreases expression EXP nimesulide results in decreased expression of CLPX mRNA CTD PMID:24136188 NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762 		JBrowse link
G Cltb clathrin, light chain B increases expression EXP nimesulide results in increased expression of CLTB mRNA CTD PMID:24136188 NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression EXP nimesulide results in increased expression of CMBL mRNA CTD PMID:24136188 NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880 		JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 decreases expression EXP nimesulide results in decreased expression of CMTM6 mRNA CTD PMID:24136188 NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230 		JBrowse link
G Cndp2 carnosine dipeptidase 2 increases expression EXP nimesulide results in increased expression of CNDP2 mRNA CTD PMID:24136188 NCBI chr18:80,314,799...80,331,900
Ensembl chr18:80,314,801...80,331,900 		JBrowse link
G Cnih4 cornichon family member 4 increases expression EXP nimesulide results in increased expression of CNIH4 mRNA CTD PMID:24136188 NCBI chr13:95,442,054...95,458,163
Ensembl chr13:95,442,054...95,459,590 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [AM 251 binds to and results in decreased activity of CNR1 protein] which results in decreased activity of nimesulide CTD PMID:20590570 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL14A1 mRNA CTD PMID:24136188 NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL18A1 mRNA CTD PMID:24136188 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP nimesulide results in decreased expression of COL1A2 mRNA CTD PMID:24136188 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL3A1 mRNA CTD PMID:24136188 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression EXP nimesulide results in decreased expression of COL6A1 mRNA CTD PMID:24136188 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107 		JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP nimesulide results in increased expression of COMMD5 mRNA CTD PMID:24136188 NCBI chr 7:110,502,492...110,503,916
Ensembl chr 7:110,479,403...110,505,897 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 increases expression EXP nimesulide results in increased expression of COMTD1 mRNA CTD PMID:24136188 NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232 		JBrowse link
G Cops5 COP9 signalosome subunit 5 increases expression EXP nimesulide results in increased expression of COPS5 mRNA CTD PMID:24136188 NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:13,975,052...13,993,387 		JBrowse link
G Coq10a coenzyme Q10A decreases expression EXP nimesulide results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr 7:1,376,591...1,387,694
Ensembl chr 7:1,376,591...1,382,722 		JBrowse link
G Coq10b coenzyme Q10B increases expression EXP nimesulide results in increased expression of COQ10B mRNA CTD PMID:24136188 NCBI chr 9:64,048,168...64,068,082
Ensembl chr 9:64,048,103...64,068,322 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression EXP nimesulide results in increased expression of COQ6 mRNA CTD PMID:24136188 NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310 		JBrowse link
G Coq8a coenzyme Q8A decreases expression EXP nimesulide results in decreased expression of COQ8A mRNA CTD PMID:24136188 NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378 		JBrowse link
G Coro1c coronin 1C decreases expression EXP nimesulide results in decreased expression of CORO1C mRNA CTD PMID:24136188 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:48,373,597...48,445,716 		JBrowse link
G Cox14 cytochrome c oxidase assembly factor COX14 increases expression EXP nimesulide results in increased expression of COX14 mRNA CTD PMID:24136188 NCBI chr 7:132,731,069...132,733,159
Ensembl chr 7:132,731,069...132,733,159 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression EXP nimesulide results in increased expression of COX17 mRNA CTD PMID:24136188 NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019 		JBrowse link
G Cox19 cytochrome c oxidase assembly factor COX19 increases expression EXP nimesulide results in increased expression of COX19 mRNA CTD PMID:24136188 NCBI chr12:20,417,389...20,426,868
Ensembl chr12:20,417,341...20,426,868 		JBrowse link
G Cp ceruloplasmin decreases expression EXP nimesulide results in decreased expression of CP mRNA CTD PMID:24136188 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP nimesulide results in decreased expression of PGCP mRNA CTD PMID:24136188 NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP nimesulide results in decreased expression of CPS1 mRNA CTD PMID:24136188 NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP nimesulide results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP nimesulide results in increased expression of CPT2 mRNA CTD PMID:24136188 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818 		JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP nimesulide results in increased expression of CRAT mRNA CTD PMID:24136188 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP nimesulide results in increased expression of CREG1 mRNA CTD PMID:24136188 NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272 		JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 increases expression EXP nimesulide results in increased expression of CRELD1 mRNA CTD PMID:24136188 NCBI chr 4:148,187,510...148,197,120
Ensembl chr 4:148,187,265...148,197,116 		JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP nimesulide results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression EXP nimesulide results in decreased expression of CROT mRNA CTD PMID:24136188 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064 		JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP nimesulide results in increased expression of CRYL1 mRNA CTD PMID:24136188 NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP nimesulide results in decreased expression of CSAD mRNA CTD PMID:24136188 NCBI chr 7:135,187,175...135,216,495
Ensembl chr 7:135,187,175...135,215,581 		JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP nimesulide results in decreased expression of CSF1R mRNA CTD PMID:24136188 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP nimesulide results in decreased expression of CSRP1 mRNA CTD PMID:24136188 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP nimesulide results in decreased expression of CTH mRNA CTD PMID:24136188 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctnnb1 catenin beta 1 affects localization
decreases expression 		ISO nimesulide affects the localization of CTNNB1 protein
nimesulide results in decreased expression of CTNNB1 		CTD PMID:15892897 PMID:16331303 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsh cathepsin H decreases expression EXP nimesulide results in decreased expression of CTSH mRNA CTD PMID:24136188 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181 		JBrowse link
G Ctsl cathepsin L increases expression EXP nimesulide results in increased expression of CTSL mRNA CTD PMID:24136188 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Ctss cathepsin S decreases expression EXP nimesulide results in decreased expression of CTSS mRNA CTD PMID:24136188 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL10 mRNA CTD PMID:22561872 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL11 mRNA CTD PMID:22561872 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP nimesulide results in decreased expression of CXCL12 mRNA CTD PMID:24136188 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of CXCL9 mRNA CTD PMID:22561872 NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299 		JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression EXP nimesulide results in decreased expression of CXXC5 mRNA CTD PMID:24136188 NCBI chr18:27,701,650...27,732,633
Ensembl chr18:27,701,188...27,732,635 		JBrowse link
G Cyb5a cytochrome b5 type A increases expression EXP nimesulide results in increased expression of CYB5A mRNA CTD PMID:24136188 NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094 		JBrowse link
G Cyb5b cytochrome b5 type B increases expression EXP nimesulide results in increased expression of CYB5B mRNA CTD PMID:24136188 NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980 		JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression EXP nimesulide results in decreased expression of CYBB mRNA CTD PMID:24136188 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression
multiple interactions 		ISO
EXP 		nimesulide analog results in decreased activity of CYP19A1 protein; nimesulide results in decreased activity of CYP19A1; nimesulide results in decreased activity of CYP19A1 protein
nimesulide analog results in decreased expression of CYP19A1 mRNA; nimesulide results in decreased expression of CYP19A1 mRNA
nimesulide analog results in decreased activity of and results in decreased expression of CYP19A1 		CTD PMID:15964185 PMID:17315855 PMID:20542113 PMID:23054057 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases glutathionylation
decreases expression 		ISO
EXP 		CYP1A2 protein results in increased glutathionylation of nimesulide
nimesulide results in decreased expression of CYP1A2 mRNA 		CTD PMID:24136188 PMID:26524229 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases glutathionylation ISO CYP1B1 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 increases expression EXP nimesulide results in increased expression of CYP20A1 mRNA CTD PMID:24136188 NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP27A1 mRNA CTD PMID:24136188 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP2A1 mRNA CTD PMID:24136188 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730 		JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression EXP nimesulide results in decreased expression of CYP2A2 mRNA CTD PMID:24136188 NCBI chr 1:91,391,492...91,417,158
Ensembl chr 1:91,391,502...91,417,158 		JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 increases expression EXP nimesulide results in increased expression of CYP2B12 mRNA CTD PMID:24136188 NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases glutathionylation
decreases expression 		ISO
EXP 		CYP2B6 protein results in increased glutathionylation of nimesulide
nimesulide results in decreased expression of CYP2B3 mRNA 		CTD PMID:24136188 PMID:26524229 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 decreases expression EXP nimesulide results in decreased expression of CYP2C23 mRNA CTD PMID:24136188 NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases glutathionylation ISO CYP2C19 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases glutathionylation ISO CYP2D6 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 increases expression EXP nimesulide results in increased expression of CYP2J3 mRNA CTD PMID:24136188 NCBI chr 5:116,335,755...116,360,677
Ensembl chr 5:116,335,755...116,360,499 		JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP2T1 mRNA CTD PMID:24136188 NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases glutathionylation 		EXP
ISO 		nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]
CYP3A4 protein results in increased glutathionylation of nimesulide 		CTD PMID:18079364 PMID:26524229 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP nimesulide results in increased expression of CYP3A9 mRNA CTD PMID:24136188 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP nimesulide results in increased expression of CYP4A1 mRNA CTD PMID:24136188 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP nimesulide results in increased expression of CYP4A3 mRNA CTD PMID:24136188 NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP nimesulide results in decreased expression of CYP4F1 mRNA CTD PMID:24136188 NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression EXP nimesulide results in decreased expression of CYP4F6 mRNA CTD PMID:24136188 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression EXP nimesulide results in decreased expression of DAAM1 mRNA CTD PMID:24136188 NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049 		JBrowse link
G Dab2 DAB adaptor protein 2 decreases expression EXP nimesulide results in decreased expression of DAB2 mRNA CTD PMID:24136188 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888 		JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP nimesulide results in decreased expression of DAG1 mRNA CTD PMID:24136188 NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP nimesulide results in decreased expression of DAPK1 mRNA CTD PMID:24136188 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581 		JBrowse link
G Dazap1 DAZ associated protein 1 increases expression EXP nimesulide results in increased expression of DAZAP1 mRNA CTD PMID:24136188 NCBI chr 7:10,074,342...10,098,810
Ensembl chr 7:10,074,849...10,095,599 		JBrowse link
G Ddc dopa decarboxylase decreases expression EXP nimesulide results in decreased expression of DDC mRNA CTD PMID:24136188 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP nimesulide results in decreased expression of DDHD1 mRNA CTD PMID:24136188 NCBI chr15:21,304,053...21,370,608
Ensembl chr15:21,303,826...21,370,608 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression 		EXP
ISO 		nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of DDIT3 protein]
nimesulide results in increased expression of DDIT3 mRNA 		CTD PMID:22940226 PMID:24136188 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression EXP nimesulide results in increased expression of DDOST mRNA CTD PMID:24136188 NCBI chr 5:155,805,612...155,812,728
Ensembl chr 5:155,805,454...155,813,121 		JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression EXP nimesulide results in decreased expression of DDX17 mRNA CTD PMID:24136188 NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747 		JBrowse link
G Ddx39a DExD-box helicase 39A increases expression EXP nimesulide results in increased expression of DDX39A mRNA CTD PMID:24136188 NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP nimesulide results in increased expression of DECR1 mRNA CTD PMID:24136188 NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033 		JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP nimesulide results in increased expression of DECR2 mRNA CTD PMID:24136188 NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397 		JBrowse link
G Derl1 derlin 1 increases expression EXP nimesulide results in increased expression of DERL1 mRNA CTD PMID:24136188 NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678 		JBrowse link
G Desi1 desumoylating isopeptidase 1 increases expression EXP nimesulide results in increased expression of DESI1 mRNA CTD PMID:24136188 NCBI chr 7:115,401,613...115,422,974
Ensembl chr 7:115,401,624...115,423,172 		JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression EXP nimesulide results in increased expression of DESI2 mRNA CTD PMID:24136188 NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression EXP nimesulide results in decreased expression of DGAT2 mRNA CTD PMID:24136188 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566 		JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit increases expression EXP nimesulide results in increased expression of DHDDS mRNA CTD PMID:24136188 NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression EXP nimesulide results in decreased expression of DHFR mRNA CTD PMID:24136188 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Dhrs4 dehydrogenase/reductase 4 increases expression EXP nimesulide results in increased expression of DHRS4 mRNA CTD PMID:24136188 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression EXP nimesulide results in increased expression of DHRS7 mRNA CTD PMID:24136188 NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B increases expression EXP nimesulide results in increased expression of DHRS7B mRNA CTD PMID:24136188 NCBI chr10:46,003,845...46,036,498
Ensembl chr10:46,003,845...46,036,499 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase decreases expression EXP nimesulide results in decreased expression of DMGDH mRNA CTD PMID:24136188 NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression EXP nimesulide results in increased expression of DNAJA3 mRNA CTD PMID:24136188 NCBI chr10:11,361,168...11,386,599
Ensembl chr10:11,361,168...11,386,599 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression EXP nimesulide results in increased expression of DNAJB1 mRNA CTD PMID:24136188 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression EXP nimesulide results in increased expression of DNAJB11 mRNA CTD PMID:24136188 NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP nimesulide results in increased expression of DNAJB9 mRNA CTD PMID:24136188 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression EXP nimesulide results in increased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:59,594,314...59,658,862
Ensembl chr15:59,594,314...59,658,987 		JBrowse link
G Dnlz DNL-type zinc finger increases expression EXP nimesulide results in increased expression of DNLZ mRNA CTD PMID:24136188 NCBI chr 3:29,568,041...29,569,937
Ensembl chr 3:29,568,041...29,569,996 		JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 increases expression EXP nimesulide results in increased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631 		JBrowse link
G Dph3 diphthamide biosynthesis 3 increases expression EXP nimesulide results in increased expression of DPH3 mRNA CTD PMID:24136188 NCBI chr16:7,294,580...7,299,996
Ensembl chr16:7,294,580...7,299,996 		JBrowse link
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory increases expression EXP nimesulide results in increased expression of DPM3 mRNA CTD PMID:24136188 NCBI chr 2:176,974,290...176,974,805
Ensembl chr15:52,612,418...52,612,696 		JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit increases expression EXP nimesulide results in increased expression of DPY30 mRNA CTD PMID:24136188 NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression EXP nimesulide results in decreased expression of DPYD mRNA CTD PMID:24136188 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:209,293,929...210,159,778 		JBrowse link
G Dpys dihydropyrimidinase decreases expression EXP nimesulide results in decreased expression of DPYS mRNA CTD PMID:24136188 NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142 		JBrowse link
G Dsc2 desmocollin 2 increases expression EXP nimesulide results in increased expression of DSC2 mRNA CTD PMID:24136188 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466 		JBrowse link
G Dtd1 D-aminoacyl-tRNA deacylase 1 increases expression EXP nimesulide results in increased expression of DTD1 mRNA CTD PMID:24136188 NCBI chr 3:152,449,193...152,611,960
Ensembl chr 3:152,452,620...152,486,304 		JBrowse link
G Dusp11 dual specificity phosphatase 11 increases expression EXP nimesulide results in increased expression of DUSP11 mRNA CTD PMID:24136188 NCBI chr 4:119,928,533...119,942,643
Ensembl chr 4:119,928,537...119,942,567 		JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression EXP nimesulide results in decreased expression of DYNLT3 mRNA CTD PMID:24136188 NCBI chr  X:16,000,425...16,009,632
Ensembl chr  X:16,000,395...16,009,627 		JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression EXP nimesulide results in increased expression of EBNA1BP2 mRNA CTD PMID:24136188 NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637 		JBrowse link
G Ebpl EBP like increases expression EXP nimesulide results in increased expression of EBPL mRNA CTD PMID:24136188 NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP nimesulide results in increased expression of ECH1 mRNA CTD PMID:24136188 NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP nimesulide results in increased expression of ECI1 mRNA CTD PMID:24136188 NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773 		JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold increases expression EXP nimesulide results in increased expression of ECPAS mRNA CTD PMID:24136188 NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908 		JBrowse link
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 increases expression EXP nimesulide results in increased expression of EDEM2 mRNA CTD PMID:24136188 NCBI chr 3:164,661,741...164,687,559
Ensembl chr 3:164,661,742...164,687,559 		JBrowse link
G Edn1 endothelin 1 multiple interactions EXP nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein] CTD PMID:21811393 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression EXP nimesulide results in increased expression of EEF1B2 mRNA CTD PMID:24136188 NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589 		JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta increases expression EXP nimesulide results in increased expression of EEF1D mRNA CTD PMID:24136188 NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression EXP nimesulide results in increased expression of EEF1E1 mRNA CTD PMID:24136188 NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687 		JBrowse link
G Egf epidermal growth factor decreases expression EXP nimesulide results in decreased expression of EGF mRNA CTD PMID:24136188 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Ehbp1 EH domain binding protein 1 decreases expression EXP nimesulide results in decreased expression of EHBP1 mRNA CTD PMID:24136188 NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579 		JBrowse link
G Ehd3 EH-domain containing 3 decreases expression EXP nimesulide results in decreased expression of EHD3 mRNA CTD PMID:24136188 NCBI chr 6:27,392,709...27,417,445
Ensembl chr 6:27,392,709...27,417,445 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 decreases expression EXP nimesulide results in decreased expression of EIF2AK1 mRNA CTD PMID:24136188 NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression EXP nimesulide results in increased expression of EIF2S1 mRNA CTD PMID:24136188 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B increases expression EXP nimesulide results in increased expression of EIF3B mRNA CTD PMID:24136188 NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939 		JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I increases expression EXP nimesulide results in increased expression of EIF3I mRNA CTD PMID:24136188 NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232 		JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M increases expression EXP nimesulide results in increased expression of EIF3M mRNA CTD PMID:24136188 NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression EXP nimesulide results in increased expression of EIF4A1 mRNA CTD PMID:24136188 NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP nimesulide results in increased expression of EIF4EBP1 mRNA CTD PMID:24136188 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 increases expression EXP nimesulide results in increased expression of EIF4G1 mRNA CTD PMID:24136188 NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression EXP nimesulide results in increased expression of EIF5 mRNA CTD PMID:24136188 NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP nimesulide results in increased expression of EIF5A mRNA CTD PMID:24136188 NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330 		JBrowse link
G Eloc elongin C increases expression EXP nimesulide results in increased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:7,444,769...7,461,187
Ensembl chr20:25,752,857...25,753,279 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression EXP nimesulide results in decreased expression of ELOVL5 mRNA CTD PMID:24136188 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP nimesulide results in decreased expression of ELOVL6 mRNA CTD PMID:24136188 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549 		JBrowse link
G Emc10 ER membrane protein complex subunit 10 increases expression EXP nimesulide results in increased expression of EMC10 mRNA CTD PMID:24136188 NCBI chr 1:104,119,040...104,125,409
Ensembl chr 1:104,119,040...104,125,368 		JBrowse link
G Emc6 ER membrane protein complex subunit 6 increases expression EXP nimesulide results in increased expression of EMC6 mRNA CTD PMID:24136188 NCBI chr10:58,292,584...58,293,850
Ensembl chr10:58,292,470...58,298,885 		JBrowse link
G Emc7 ER membrane protein complex subunit 7 increases expression EXP nimesulide results in increased expression of EMC7 mRNA CTD PMID:24136188 NCBI chr 3:119,714,617...119,728,748
Ensembl chr 3:119,718,357...119,730,486 		JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP nimesulide results in increased expression of EMC8 mRNA CTD PMID:24136188 NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235 		JBrowse link
G Eml4 EMAP like 4 decreases expression EXP nimesulide results in decreased expression of EML4 mRNA CTD PMID:24136188 NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439 		JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP nimesulide results in increased expression of ENC1 mRNA CTD PMID:24136188 NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721 		JBrowse link
G Enpep glutamyl aminopeptidase decreases expression EXP nimesulide results in decreased expression of ENPEP mRNA CTD PMID:24136188 NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression EXP nimesulide results in increased expression of ENPP2 mRNA CTD PMID:24136188 NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP nimesulide results in increased expression of ENTPD5 mRNA CTD PMID:24136188 NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 increases expression EXP nimesulide results in increased expression of EPB41 mRNA CTD PMID:24136188 NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases glutathionylation
increases expression 		ISO
EXP 		EPHX1 protein results in decreased glutathionylation of nimesulide
nimesulide results in increased expression of EPHX1 mRNA 		CTD PMID:24136188 PMID:26524229 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP nimesulide results in increased expression of EPRS1 mRNA CTD PMID:24136188 NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509 		JBrowse link
G Ereg epiregulin multiple interactions
increases expression 		ISO nimesulide inhibits the reaction [LHB results in increased expression of EREG mRNA]
nimesulide results in increased expression of EREG mRNA 		CTD PMID:16888076 PMID:32816093 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression EXP nimesulide results in increased expression of ERP44 mRNA CTD PMID:24136188 NCBI chr 5:67,313,245...67,406,207
Ensembl chr 5:67,312,098...67,406,444 		JBrowse link
G Esd esterase D increases expression EXP nimesulide results in increased expression of ESD mRNA CTD PMID:24136188 NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508 		JBrowse link
G Exosc4 exosome component 4 increases expression EXP nimesulide results in increased expression of EXOSC4 mRNA CTD PMID:24136188 NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820 		JBrowse link
G Exosc5 exosome component 5 increases expression EXP nimesulide results in increased expression of EXOSC5 mRNA CTD PMID:24136188 NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression EXP nimesulide results in decreased expression of EXT1 mRNA CTD PMID:24136188 NCBI chr 7:86,265,651...86,544,488
Ensembl chr 7:86,259,900...86,544,567 		JBrowse link
G F10 coagulation factor X decreases expression EXP nimesulide results in decreased expression of F10 mRNA CTD PMID:24136188 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280 		JBrowse link
G F2 coagulation factor II, thrombin decreases activity
multiple interactions 		ISO
EXP 		nimesulide results in decreased activity of F2
nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [F2 protein affects the localization of PRKCE protein] 		CTD PMID:17379757 PMID:21811393 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased expression of F3 mRNA] CTD PMID:25339356 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
decreases expression 		ISO
EXP 		[nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]
nimesulide results in decreased expression of FAAH mRNA 		CTD PMID:20702753 PMID:24136188 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP nimesulide results in decreased expression of FABP5 mRNA CTD PMID:24136188 NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP nimesulide results in decreased expression of FADS1 mRNA CTD PMID:24136188 NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP nimesulide results in decreased expression of FADS2 mRNA CTD PMID:24136188 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A increases expression EXP nimesulide results in increased expression of FAM3A mRNA CTD PMID:24136188 NCBI chr  X:157,317,993...157,326,640
Ensembl chr  X:157,317,990...157,326,612 		JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta increases expression EXP nimesulide results in increased expression of FARSB mRNA CTD PMID:24136188 NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505 		JBrowse link
G Fasn fatty acid synthase decreases expression EXP nimesulide results in decreased expression of FASN mRNA CTD PMID:24136188 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fbl fibrillarin increases expression EXP nimesulide results in increased expression of FBL mRNA CTD PMID:24136188 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506 		JBrowse link
G Fbxo31 F-box protein 31 increases expression EXP nimesulide results in increased expression of FBXO31 mRNA CTD PMID:24136188 NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674 		JBrowse link
G Fcf1 Fcf1 rRNA-processing protein increases expression EXP nimesulide results in increased expression of NOMO1 mRNA CTD PMID:24136188 NCBI chr 6:110,348,854...110,360,715
Ensembl chr 6:110,348,845...110,372,221 		JBrowse link
G Fcgr2a Fc gamma receptor 2A decreases expression EXP nimesulide results in decreased expression of FCGR2A mRNA CTD PMID:24136188 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Fchsd2 FCH and double SH3 domains 2 decreases expression EXP nimesulide results in decreased expression of FCHSD2 mRNA CTD PMID:24136188 NCBI chr 1:164,775,916...165,097,391
Ensembl chr 1:164,775,926...165,097,391 		JBrowse link
G Fcna ficolin A decreases expression EXP nimesulide results in decreased expression of FCNA mRNA CTD PMID:24136188 NCBI chr 3:28,844,036...28,847,441
Ensembl chr 3:28,844,039...28,847,237 		JBrowse link
G Fdx2 ferredoxin 2 increases expression EXP nimesulide results in increased expression of FDX2 mRNA CTD PMID:24136188 NCBI chr 8:27,881,091...27,886,230
Ensembl chr 8:27,881,091...27,886,015 		JBrowse link
G Fech ferrochelatase increases expression EXP nimesulide results in increased expression of FECH mRNA CTD PMID:24136188 NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546 		JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP nimesulide results in decreased expression of FGA mRNA CTD PMID:24136188 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 increases expression EXP nimesulide results in increased expression of FITM2 mRNA CTD PMID:24136188 NCBI chr 3:172,560,781...172,567,291
Ensembl chr 3:172,560,781...172,567,291 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP nimesulide results in increased expression of FKBP11 mRNA CTD PMID:24136188 NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123 		JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 increases expression EXP nimesulide results in increased expression of FKBP3 mRNA CTD PMID:24136188 NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression EXP nimesulide results in decreased expression of FMO1 mRNA CTD PMID:24136188 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874 		JBrowse link
G Fn1 fibronectin 1 decreases expression EXP nimesulide results in decreased expression of FN1 mRNA CTD PMID:24136188 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Foxn3 forkhead box N3 decreases expression EXP nimesulide results in decreased expression of FOXN3 mRNA CTD PMID:24136188 NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040 		JBrowse link
G Fpgs folylpolyglutamate synthase increases expression EXP nimesulide results in increased expression of FPGS mRNA CTD PMID:24136188 NCBI chr 3:36,370,505...36,391,314
Ensembl chr 3:36,370,300...36,391,068 		JBrowse link
G Fstl1 follistatin-like 1 decreases expression EXP nimesulide results in decreased expression of FSTL1 mRNA CTD PMID:24136188 NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase increases expression EXP nimesulide results in increased expression of FTCD mRNA CTD PMID:24136188 NCBI chr20:12,054,710...12,068,219
Ensembl chr20:12,054,711...12,068,237 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP nimesulide results in increased expression of FTL1 mRNA CTD PMID:24136188 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915 		JBrowse link
G Fuca1 alpha-L-fucosidase 1 decreases expression EXP nimesulide results in decreased expression of FUCA1 mRNA CTD PMID:24136188 NCBI chr 5:153,436,262...153,453,512
Ensembl chr 5:153,436,248...153,453,511 		JBrowse link
G Fxn frataxin increases expression EXP nimesulide results in increased expression of FXN mRNA CTD PMID:24136188 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:231,300,150...231,323,989 		JBrowse link
G Fzd8 frizzled class receptor 8 decreases expression EXP nimesulide results in decreased expression of FZD8 mRNA CTD PMID:24136188 NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961 		JBrowse link
G Gaa alpha glucosidase increases expression EXP nimesulide results in increased expression of GAA mRNA CTD PMID:24136188 NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP nimesulide results in increased expression of GADD45A mRNA CTD PMID:24136188 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP nimesulide results in decreased expression of GADD45G mRNA CTD PMID:24136188 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Galk1 galactokinase 1 increases expression EXP nimesulide results in increased expression of GALK1 mRNA CTD PMID:24136188 NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258 		JBrowse link
G Galm galactose mutarotase decreases expression EXP nimesulide results in decreased expression of GALM mRNA CTD PMID:24136188 NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417 		JBrowse link
G Gas6 growth arrest specific 6 decreases expression EXP nimesulide results in decreased expression of GAS6 mRNA CTD PMID:24136188 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088 		JBrowse link
G Gata6 GATA binding protein 6 decreases expression EXP nimesulide results in decreased expression of GATA6 mRNA CTD PMID:24136188 NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322 		JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP nimesulide results in decreased expression of GC mRNA CTD PMID:24136188 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673 		JBrowse link
G Gcat glycine C-acetyltransferase decreases expression EXP nimesulide results in decreased expression of GCAT mRNA CTD PMID:24136188 NCBI chr 7:112,475,572...112,481,920
Ensembl chr 7:112,475,496...112,482,664 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP nimesulide results in increased expression of GCH1 mRNA CTD PMID:24136188 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412 		JBrowse link
G Gckr glucokinase regulator decreases expression EXP nimesulide results in decreased expression of GCKR mRNA CTD PMID:24136188 NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP nimesulide results in increased expression of GCLC mRNA CTD PMID:24136188 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP nimesulide results in increased expression of GCLM mRNA CTD PMID:24136188 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gda guanine deaminase increases expression EXP nimesulide results in increased expression of GDA mRNA CTD PMID:24136188 NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348 		JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 increases expression EXP nimesulide results in increased expression of GDE1 mRNA CTD PMID:24136188 NCBI chr 1:182,451,182...182,466,569
Ensembl chr 1:182,451,184...182,466,772 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase increases expression EXP nimesulide results in increased expression of GGCT mRNA CTD PMID:24136188 NCBI chr 4:85,453,387...85,459,597
Ensembl chr 4:85,453,387...85,470,224 		JBrowse link
G Ggh gamma-glutamyl hydrolase increases expression EXP nimesulide results in increased expression of GGH mRNA CTD PMID:24136188 NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression EXP nimesulide results in increased expression of GHITM mRNA CTD PMID:24136188 NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123 		JBrowse link
G Ghr growth hormone receptor decreases expression EXP nimesulide results in decreased expression of GHR mRNA CTD PMID:24136188 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Gk glycerol kinase decreases expression EXP nimesulide results in decreased expression of GK mRNA CTD PMID:24136188 NCBI chr  X:54,106,708...54,189,940
Ensembl chr  X:54,112,214...54,196,701 		JBrowse link
G Gldc glycine decarboxylase decreases expression EXP nimesulide results in decreased expression of GLDC mRNA CTD PMID:24136188 NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604 		JBrowse link
G Glrx2 glutaredoxin 2 increases expression EXP nimesulide results in increased expression of GLRX2 mRNA CTD PMID:24136188 NCBI chr13:58,032,199...58,055,061
Ensembl chr13:58,032,401...58,043,150 		JBrowse link
G Gls2 glutaminase 2 decreases expression EXP nimesulide results in decreased expression of GLS2 mRNA CTD PMID:24136188 NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013 		JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP nimesulide results in decreased expression of GLUD1 mRNA CTD PMID:24136188 NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP nimesulide results in decreased expression of GLUL mRNA CTD PMID:24136188 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520 		JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP nimesulide results in increased expression of GLYAT mRNA CTD PMID:24136188 NCBI chr 1:219,128,798...219,149,615
Ensembl chr 1:219,128,811...219,150,774 		JBrowse link
G Glyatl2 glycine-N-acyltransferase-like 2 increases expression EXP nimesulide results in increased expression of GLYATL2 mRNA CTD PMID:24136188 NCBI chr 1:219,232,154...219,265,142
Ensembl chr 1:219,232,103...219,266,322 		JBrowse link
G Gm2a ganglioside GM2 activator decreases expression EXP nimesulide results in decreased expression of GM2A mRNA CTD PMID:24136188 NCBI chr10:39,719,919...39,732,452
Ensembl chr10:39,719,938...39,732,451 		JBrowse link
G Gmppa GDP-mannose pyrophosphorylase A increases expression EXP nimesulide results in increased expression of GMPPA mRNA CTD PMID:24136188 NCBI chr 9:84,375,373...84,382,917
Ensembl chr 9:84,375,425...84,382,916 		JBrowse link
G Gmpr2 guanosine monophosphate reductase 2 increases expression EXP nimesulide results in increased expression of GMPR2 mRNA CTD PMID:24136188 NCBI chr15:33,135,455...33,144,923
Ensembl chr15:33,135,682...33,144,899 		JBrowse link
G Gmps guanine monophosphate synthase increases expression EXP nimesulide results in increased expression of GMPS mRNA CTD PMID:24136188 NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986 		JBrowse link
G Gnas GNAS complex locus decreases expression EXP nimesulide results in decreased expression of GNAS mRNA CTD PMID:24136188 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression EXP nimesulide results in decreased expression of GNE mRNA CTD PMID:24136188 NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251 		JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP nimesulide results in increased expression of GNL3 mRNA CTD PMID:24136188 NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP nimesulide results in decreased expression of GNMT mRNA CTD PMID:24136188 NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692 		JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase decreases expression EXP nimesulide results in decreased expression of GNS mRNA CTD PMID:24136188 NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650 		JBrowse link
G Golt1a golgi transport 1A increases expression EXP nimesulide results in increased expression of GOLT1A mRNA CTD PMID:24136188 NCBI chr13:47,312,412...47,325,176
Ensembl chr13:47,322,002...47,325,175 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP nimesulide results in decreased expression of GPAM mRNA CTD PMID:24136188 NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 increases expression EXP nimesulide results in increased expression of GPAT4 mRNA CTD PMID:24136188 NCBI chr16:75,515,935...75,555,431
Ensembl chr16:75,521,640...75,557,847 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression EXP nimesulide results in decreased expression of GPLD1 mRNA CTD PMID:24136188 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP nimesulide results in increased expression of GPT mRNA CTD PMID:24136188 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression EXP nimesulide results in decreased expression of GPT2 mRNA CTD PMID:24136188 NCBI chr19:37,700,023...37,734,551
Ensembl chr19:37,691,901...37,733,917 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions 		ISO
EXP 		nimesulide results in decreased expression of GPX1 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA]; Silymarin inhibits the reaction [nimesulide results in decreased expression of GPX1 mRNA] 		CTD PMID:18848576 PMID:22509279 PMID:24136188 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Grn granulin precursor decreases expression EXP nimesulide results in decreased expression of GRN mRNA CTD PMID:24136188 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases activity ISO nimesulide results in decreased activity of GSK3B protein CTD PMID:16331303 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression
decreases activity
decreases expression
multiple interactions 		EXP nimesulide results in increased expression of GSR mRNA
nimesulide results in decreased activity of GSR protein
nimesulide results in decreased expression of GSR mRNA
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased activity of GSR protein]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in decreased expression of GSR mRNA]; Silymarin inhibits the reaction [nimesulide results in decreased activity of GSR protein]; Silymarin inhibits the reaction [nimesulide results in decreased expression of GSR mRNA] 		CTD PMID:22509279 PMID:24136188 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gss glutathione synthetase increases expression EXP nimesulide results in increased expression of GSS mRNA CTD PMID:24136188 NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP nimesulide results in increased expression of GSTA2 mRNA CTD PMID:24136188 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP nimesulide results in increased expression of GSTA3 mRNA CTD PMID:24136188 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP nimesulide results in increased expression of GSTA4 mRNA CTD PMID:24136188 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP nimesulide results in increased expression of GSTM1 mRNA CTD PMID:24136188 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression EXP nimesulide results in increased expression of GSTM4 mRNA CTD PMID:24136188 NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP nimesulide results in increased expression of GSTP1 mRNA CTD PMID:24136188 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Gstp3 glutathione S-transferase pi 3 decreases expression EXP nimesulide results in decreased expression of GSTP3 mRNA CTD PMID:24136188 NCBI chr 1:210,785,151...210,787,705
Ensembl chr 1:210,785,151...210,787,684 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression EXP nimesulide results in decreased expression of GSTZ1 mRNA CTD PMID:24136188 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233 		JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression EXP nimesulide results in increased expression of GTF2H1 mRNA CTD PMID:24136188 NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727 		JBrowse link
G Gtf3a general transcription factor III A increases expression EXP nimesulide results in increased expression of GTF3A mRNA CTD PMID:24136188 NCBI chr12:13,250,643...13,258,587
Ensembl chr12:13,250,644...13,258,587 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression EXP nimesulide results in decreased expression of GUCY1A1 mRNA CTD PMID:24136188 NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737 		JBrowse link
G Guk1 guanylate kinase 1 increases expression EXP nimesulide results in increased expression of GUK1 mRNA CTD PMID:24136188 NCBI chr10:44,471,075...44,488,332
Ensembl chr10:44,471,085...44,479,355 		JBrowse link
G Gulo gulonolactone (L-) oxidase decreases expression EXP nimesulide results in decreased expression of GULO mRNA CTD PMID:24136188 NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422 		JBrowse link
G H1f0 H1.0 linker histone decreases expression EXP nimesulide results in decreased expression of H1F0 mRNA CTD PMID:24136188 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein] CTD PMID:21745461 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 increases expression EXP nimesulide results in increased expression of HACL1 mRNA CTD PMID:24136188 NCBI chr16:6,831,293...6,869,410
Ensembl chr16:6,833,268...6,869,410 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP nimesulide results in increased expression of HADHB mRNA CTD PMID:24136188 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835 		JBrowse link
G Hal histidine ammonia lyase decreases expression EXP nimesulide results in decreased expression of HAL mRNA CTD PMID:24136188 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744 		JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP nimesulide results in decreased expression of HAO1 mRNA CTD PMID:24136188 NCBI chr 3:142,102,873...142,281,527
Ensembl chr 3:142,224,612...142,281,494 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression EXP nimesulide results in increased expression of HARS1 mRNA CTD PMID:24136188 NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 decreases expression EXP nimesulide results in decreased expression of HBA-A1 mRNA CTD PMID:24136188 NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP nimesulide results in decreased expression of HBA1 mRNA CTD PMID:24136188 NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141 		JBrowse link
G Hdac2 histone deacetylase 2 decreases expression EXP nimesulide results in decreased expression of HDAC2 mRNA CTD PMID:24136188 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hdgf heparin binding growth factor increases expression EXP nimesulide results in increased expression of HDGF mRNA CTD PMID:24136188 NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression EXP nimesulide results in increased expression of HERPUD1 mRNA CTD PMID:24136188 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP nimesulide results in decreased expression of HES6 mRNA CTD PMID:24136188 NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096 		JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP nimesulide results in decreased expression of HHEX mRNA CTD PMID:24136188 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases expression EXP nimesulide results in increased expression of HIBCH mRNA CTD PMID:24136188 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP nimesulide results in increased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888 		JBrowse link
G Higd2a HIG1 hypoxia inducible domain family, member 2A increases expression EXP nimesulide results in increased expression of HIGD2A mRNA CTD PMID:24136188 NCBI chr17:10,026,961...10,027,885
Ensembl chr17:10,026,961...10,027,874 		JBrowse link
G Hikeshi heat shock protein nuclear import factor hikeshi increases expression EXP nimesulide results in increased expression of HIKESHI mRNA CTD PMID:24136188 NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911 		JBrowse link
G Hint2 histidine triad nucleotide binding protein 2 increases expression EXP nimesulide results in increased expression of HINT2 mRNA CTD PMID:24136188 NCBI chr 5:62,700,383...62,702,638
Ensembl chr 5:62,700,384...62,702,915 		JBrowse link
G Hmgb2 high mobility group box 2 decreases expression EXP nimesulide results in decreased expression of HMGB2 mRNA CTD PMID:24136188 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP nimesulide results in increased expression of HMGCR mRNA CTD PMID:24136188 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 increases expression EXP nimesulide results in increased expression of HMGN1 mRNA CTD PMID:24136188 NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP nimesulide results in increased expression of HMOX1 mRNA CTD PMID:24136188 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 decreases expression EXP nimesulide results in decreased expression of HOGA1 mRNA CTD PMID:24136188 NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:250,806,255...250,833,869 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression EXP nimesulide results in decreased expression of HOOK3 mRNA CTD PMID:24136188 NCBI chr16:72,656,929...72,751,696
Ensembl chr16:72,657,019...72,764,071 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP nimesulide results in increased expression of HPRT1 mRNA CTD PMID:24136188 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of CCND1 mRNA]; nimesulide inhibits the reaction [[4-Nitroquinoline-1-oxide co-treated with HRAS] results in increased expression of PTGS2 mRNA] CTD PMID:20043093 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression EXP nimesulide results in increased expression of HSD17B12 mRNA CTD PMID:24136188 NCBI chr 3:100,445,393...100,568,898
Ensembl chr 3:100,445,400...100,568,938 		JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 decreases expression EXP nimesulide results in decreased expression of HSD17B13 mRNA CTD PMID:24136188 NCBI chr14:6,056,708...6,071,463
Ensembl chr14:6,056,774...6,072,823 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression EXP nimesulide results in increased expression of HSD17B4 mRNA CTD PMID:24136188 NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression EXP nimesulide results in increased expression of HSDL2 mRNA CTD PMID:24136188 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO nimesulide results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP nimesulide results in increased expression of HSP90AA1 mRNA CTD PMID:24136188 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP nimesulide results in increased expression of HSP90AB1 mRNA CTD PMID:24136188 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspa13 heat shock protein family A (Hsp70) member 13 increases expression EXP nimesulide results in increased expression of HSPA13 mRNA CTD PMID:24136188 NCBI chr11:27,862,717...27,876,898
Ensembl chr11:27,862,593...27,876,898 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP nimesulide results in increased expression of HSPA8 mRNA CTD PMID:24136188 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP nimesulide results in increased expression of HSPB1 mRNA CTD PMID:24136188 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression EXP nimesulide results in increased expression of HSPB8 mRNA CTD PMID:24136188 NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 increases expression EXP nimesulide results in increased expression of HSPBP1 mRNA CTD PMID:24136188 NCBI chr 1:78,194,067...78,217,836
Ensembl chr 1:78,189,305...78,217,835 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP nimesulide results in increased expression of HSPD1 mRNA CTD PMID:24136188 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP nimesulide results in increased expression of HSPE1 mRNA CTD PMID:24136188 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP nimesulide results in increased expression of HSPH1 mRNA CTD PMID:24136188 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP nimesulide results in increased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815 		JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression EXP nimesulide results in decreased expression of HTRA1 mRNA CTD PMID:24136188 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620 		JBrowse link
G Hyal3 hyaluronidase 3 decreases expression EXP nimesulide results in decreased expression of HYAL3 mRNA CTD PMID:24136188 NCBI chr 8:117,133,028...117,138,663
Ensembl chr 8:117,132,649...117,139,289 		JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 increases expression EXP nimesulide results in increased expression of HYCC2 mRNA CTD PMID:24136188 NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186 		JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression EXP nimesulide results in increased expression of HYOU1 mRNA CTD PMID:24136188 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:53,602,604...53,614,997 		JBrowse link
G Iba57 iron-sulfur cluster assembly factor IBA57 increases expression EXP nimesulide results in increased expression of IBA57 mRNA CTD PMID:24136188 NCBI chr10:44,441,579...44,450,368
Ensembl chr10:44,441,579...44,450,368 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ketotifen co-treated with nimesulide] results in decreased expression of ICAM1 protein CTD PMID:12121561 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id4 inhibitor of DNA binding 4 decreases expression EXP nimesulide results in decreased expression of ID4 mRNA CTD PMID:24136188 NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression EXP nimesulide results in decreased expression of IFIT2 mRNA CTD PMID:24136188 NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression EXP nimesulide results in decreased expression of IFITM1 mRNA CTD PMID:24136188 NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IFNB1 mRNA CTD PMID:22561872 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression 		EXP
ISO 		nimesulide inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Dinoprostone]
nimesulide results in decreased expression of IFNG
[nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IFNG mRNA
[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide 		CTD PMID:12911628 PMID:19362101 PMID:22561872 PMID:24136188 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression EXP nimesulide results in increased expression of IFRD1 mRNA CTD PMID:24136188 NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131 		JBrowse link
G Ifrd2 interferon-related developmental regulator 2 increases expression EXP nimesulide results in increased expression of IFRD2 mRNA CTD PMID:24136188 NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP nimesulide results in decreased expression of IGF1 mRNA CTD PMID:23142791 PMID:24136188 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP nimesulide results in decreased expression of IGFALS mRNA CTD PMID:24136188 NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP nimesulide results in decreased expression of IGFBP3 mRNA CTD PMID:24136188 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP nimesulide results in decreased expression of IGFBP7 mRNA CTD PMID:24136188 NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Lipopolysaccharides co-treated with nimesulide] results in decreased expression of IL10 CTD PMID:14984594 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nimesulide CTD PMID:19362101 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression 		ISO
EXP 		[Ketotifen co-treated with nimesulide] results in decreased expression of IL1B protein; nimesulide inhibits the reaction [IL1B results in increased activity of EDNRB]; nimesulide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL1B protein]; nimesulide inhibits the reaction [Zymosan analog results in increased expression of IL1B protein]
nimesulide results in decreased expression of IL1B mRNA
nimesulide results in increased expression of IL1B
nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA] 		CTD PMID:12121561 PMID:12126971 PMID:12946449 PMID:22940226 PMID:24136188 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [nimesulide results in decreased activity of PTGS2 protein] which results in increased expression of IL23A mRNA CTD PMID:22561872 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Il24 interleukin 24 increases expression ISO nimesulide results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Il4r interleukin 4 receptor decreases expression EXP nimesulide results in decreased expression of IL4RA mRNA CTD PMID:24136188 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP 		nimesulide inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of IL6 protein]; nimesulide inhibits the reaction [Zymosan analog results in increased expression of IL6 protein]
nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of IL6 mRNA]
nimesulide inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] 		CTD PMID:12946449 PMID:19931610 PMID:22940226 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Imp3 IMP U3 small nucleolar ribonucleoprotein 3 increases expression EXP nimesulide results in increased expression of IMP3 mRNA CTD PMID:24136188 NCBI chr 8:66,235,498...66,236,386 JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression EXP nimesulide results in increased expression of IMP4 mRNA CTD PMID:24136188 NCBI chr 9:44,150,029...44,155,167
Ensembl chr 9:44,150,337...44,157,751 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression EXP nimesulide results in increased expression of IMPDH2 mRNA CTD PMID:24136188 NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873 		JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP nimesulide results in decreased expression of INHBA mRNA CTD PMID:24136188 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Inhbc inhibin subunit beta C decreases expression EXP nimesulide results in decreased expression of INHBC mRNA CTD PMID:24136188 NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919 		JBrowse link
G Inhbe inhibin subunit beta E decreases expression EXP nimesulide results in decreased expression of INHBE mRNA CTD PMID:24136188 NCBI chr 7:65,061,531...65,064,519
Ensembl chr 7:65,061,531...65,064,519 		JBrowse link
G Inhca inhibitor of carbonic anhydrase decreases expression EXP nimesulide results in decreased expression of INHCA mRNA CTD PMID:24136188 NCBI chr 8:112,715,733...112,753,950
Ensembl chr 8:112,702,085...112,766,829 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP nimesulide inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; nimesulide inhibits the reaction [Dietary Fats results in increased expression of INS1] CTD PMID:19247274 PMID:20039930 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Ipo4 importin 4 increases expression EXP nimesulide results in increased expression of IPO4 mRNA CTD PMID:24136188 NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241 		JBrowse link
G Ipo5 importin 5 increases expression EXP nimesulide results in increased expression of IPO5 mRNA CTD PMID:24136188 NCBI chr15:104,397,626...104,447,985
Ensembl chr15:104,397,276...104,447,985 		JBrowse link
G Ipo7 importin 7 increases expression EXP nimesulide results in increased expression of IPO7 mRNA CTD PMID:24136188 NCBI chr 1:173,497,472...173,537,707
Ensembl chr 1:173,497,503...173,536,778 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression EXP nimesulide results in increased expression of IRAK1 mRNA CTD PMID:24136188 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Irf1 interferon regulatory factor 1 decreases expression EXP nimesulide results in decreased expression of IRF1 mRNA CTD PMID:24136188 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947 		JBrowse link
G Irf6 interferon regulatory factor 6 decreases expression EXP nimesulide results in decreased expression of IRF6 mRNA CTD PMID:24136188 NCBI chr13:107,200,876...107,220,083
Ensembl chr13:107,200,731...107,220,049 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP nimesulide results in increased expression of ISYNA1 mRNA CTD PMID:24136188 NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 decreases expression EXP nimesulide results in decreased expression of ITIH1 mRNA CTD PMID:24136188 NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 decreases expression EXP nimesulide results in decreased expression of ITIH2 mRNA CTD PMID:24136188 NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP nimesulide results in decreased expression of IVD mRNA CTD PMID:24136188 NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160 		JBrowse link
G Iyd iodotyrosine deiodinase decreases expression EXP nimesulide results in decreased expression of IYD mRNA CTD PMID:24136188 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
G Jagn1 jagunal homolog 1 increases expression EXP nimesulide results in increased expression of JAGN1 mRNA CTD PMID:24136188 NCBI chr 4:148,147,213...148,151,915
Ensembl chr 4:148,147,229...148,151,915 		JBrowse link
G Jak1 Janus kinase 1 decreases expression EXP nimesulide results in decreased expression of JAK1 mRNA CTD PMID:24136188 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758 		JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO Nimesulide decreases phoshphorylation of JAK2 in esophagus squamous epithelium RGD PMID:25724470 RGD:127285656 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jpt2 Jupiter microtubule associated homolog 2 increases expression EXP nimesulide results in increased expression of JPT2 mRNA CTD PMID:24136188 NCBI chr10:14,467,652...14,487,769
Ensembl chr10:14,467,661...14,535,664 		JBrowse link
G Jup junction plakoglobin decreases expression EXP nimesulide results in decreased expression of JUP mRNA CTD PMID:24136188 NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429 		JBrowse link
G Kcmf1 potassium channel modulatory factor 1 increases expression EXP nimesulide results in increased expression of KCMF1 mRNA CTD PMID:24136188 NCBI chr 4:106,447,974...106,508,359
Ensembl chr 4:106,447,981...106,508,359 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO nimesulide results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression EXP nimesulide results in increased expression of KCTD5 mRNA CTD PMID:24136188 NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062 		JBrowse link
G Khk ketohexokinase decreases expression EXP nimesulide results in decreased expression of KHK mRNA CTD PMID:24136188 NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:31,165,248...31,175,481 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of KLF4 mRNA] CTD PMID:25339356 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Klkb1 kallikrein B1 increases response to substance
multiple interactions 		ISO KLKB1 gene mutant form results in increased susceptibility to nimesulide
nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased expression of F3 mRNA]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in decreased susceptibility to Rose Bengal]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased abundance of 6-Ketoprostaglandin F1 alpha]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of KLF4 mRNA]; nimesulide inhibits the reaction [KLKB1 gene mutant form results in increased expression of SIRT1 mRNA] 		CTD PMID:25339356 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339 		JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression EXP nimesulide results in decreased expression of KMO mRNA CTD PMID:24136188 NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151 		JBrowse link
G Kng1 kininogen 1 multiple interactions EXP nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [KNG1 protein affects the localization of PRKCE protein] CTD PMID:21811393 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148 		JBrowse link
G Kng2 kininogen 2 decreases expression EXP nimesulide results in decreased expression of KNG2 mRNA CTD PMID:24136188 NCBI chr11:91,418,470...91,440,841
Ensembl chr11:91,414,207...91,441,259 		JBrowse link
G Krt10 keratin 10 multiple interactions ISO [[(4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-1,3-thiazol-5-yl)methyl)sulfanyl)-2-methylphenoxy)acetic acid binds to and results in increased activity of PPARD protein] co-treated with [nimesulide results in decreased activity of PTGS2 protein]] results in increased expression of KRT10 mRNA CTD PMID:19748995 NCBI chr10:84,834,865...84,839,160
Ensembl chr10:84,834,840...84,839,160 		JBrowse link
G Krt8 keratin 8 increases expression EXP nimesulide results in increased expression of KRT8 mRNA CTD PMID:24136188 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Kxd1 KxDL motif containing 1 increases expression EXP nimesulide results in increased expression of KXD1 mRNA CTD PMID:24136188 NCBI chr16:18,929,316...18,950,239
Ensembl chr16:18,936,356...18,950,237 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases expression EXP nimesulide results in increased expression of KYAT1 mRNA CTD PMID:24136188 NCBI chr 3:33,857,407...33,891,153
Ensembl chr 3:33,857,743...33,890,642 		JBrowse link
G Kynu kynureninase decreases expression EXP nimesulide results in decreased expression of KYNU mRNA CTD PMID:24136188 NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 increases expression EXP nimesulide results in increased expression of LAMTOR1 mRNA CTD PMID:24136188 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:165,684,091...165,703,178 		JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 increases expression EXP nimesulide results in increased expression of LAMTOR2 mRNA CTD PMID:24136188 NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:176,306,280...176,310,730 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP nimesulide results in increased expression of LAMTOR4 mRNA CTD PMID:24136188 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:22,372,269...22,376,090 		JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression EXP nimesulide results in decreased expression of LAP3 mRNA CTD PMID:24136188 NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891 		JBrowse link
G Laptm4a lysosomal protein transmembrane 4 alpha increases expression EXP nimesulide results in increased expression of LAPTM4A mRNA CTD PMID:24136188 NCBI chr 6:37,438,503...37,456,238
Ensembl chr 6:37,438,121...37,456,223 		JBrowse link
G Laptm4b lysosomal protein transmembrane 4 beta decreases expression EXP nimesulide results in decreased expression of LAPTM4B mRNA CTD PMID:24136188 NCBI chr 7:67,319,438...67,362,547
Ensembl chr 7:67,319,542...67,363,258 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 decreases expression EXP nimesulide results in decreased expression of LCMT1 mRNA CTD PMID:24136188 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 decreases expression EXP nimesulide results in decreased expression of LCP1 mRNA CTD PMID:24136188 NCBI chr15:56,846,375...56,954,090
Ensembl chr15:56,847,433...56,954,092 		JBrowse link
G Lct lactase affects activity
increases activity
multiple interactions
decreases activity 		EXP nimesulide affects the activity of LCT protein
nimesulide results in increased activity of LCT; nimesulide results in increased activity of LCT protein
[nimesulide results in decreased activity of LCT protein] which results in decreased transport of Glucose 		CTD PMID:16382204 PMID:16855794 PMID:17147060 PMID:18604318 NCBI chr13:42,334,347...42,376,872
Ensembl chr13:42,334,347...42,376,872 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 decreases expression EXP nimesulide results in decreased expression of LECT2 mRNA CTD PMID:24136188 NCBI chr17:8,050,034...8,056,256
Ensembl chr17:8,050,034...8,056,256 		JBrowse link
G Leprotl1 leptin receptor overlapping transcript-like 1 increases expression EXP nimesulide results in increased expression of LEPROTL1 mRNA CTD PMID:24136188 NCBI chr16:64,744,148...64,756,776
Ensembl chr16:64,743,717...64,756,776 		JBrowse link
G Lgalsl galectin-like decreases expression EXP nimesulide results in decreased expression of LGALSL mRNA CTD PMID:24136188 NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487 		JBrowse link
G Lgmn legumain decreases expression EXP nimesulide results in decreased expression of LGMN mRNA CTD PMID:24136188 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO nimesulide inhibits the reaction [LHB results in increased expression of AREG mRNA]; nimesulide inhibits the reaction [LHB results in increased expression of AREG protein]; nimesulide inhibits the reaction [LHB results in increased expression of EREG mRNA] CTD PMID:16888076 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase decreases expression EXP nimesulide results in decreased expression of LHPP mRNA CTD PMID:24136188 NCBI chr 1:196,833,516...196,924,687
Ensembl chr 1:196,833,523...196,924,871 		JBrowse link
G Lipc lipase C, hepatic type decreases expression EXP nimesulide results in decreased expression of LIPC mRNA CTD PMID:24136188 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression EXP nimesulide results in decreased expression of LRAT mRNA CTD PMID:24136188 NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148 		JBrowse link
G Lrp5 LDL receptor related protein 5 decreases expression EXP nimesulide results in decreased expression of LRP5 mRNA CTD PMID:24136188 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822 		JBrowse link
G Lrrc28 leucine rich repeat containing 28 increases expression EXP nimesulide results in increased expression of LRRC28 mRNA CTD PMID:24136188 NCBI chr 1:130,526,757...130,655,991
Ensembl chr 1:130,537,930...130,655,949 		JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression EXP nimesulide results in decreased expression of LTA4H mRNA CTD PMID:24136188 NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641 		JBrowse link
G Ltbr lymphotoxin beta receptor increases expression EXP nimesulide results in increased expression of LTBR mRNA CTD PMID:24136188 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296 		JBrowse link
G Luc7l2 LUC7 pre-mRNA splicing factor like 2 decreases expression EXP nimesulide results in decreased expression of LUC7L2 mRNA CTD PMID:24136188 NCBI chr 4:68,251,435...68,314,861
Ensembl chr 4:68,271,414...68,314,837 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression EXP nimesulide results in decreased expression of LY6E mRNA CTD PMID:24136188 NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression EXP nimesulide results in decreased expression of LYVE1 mRNA CTD PMID:24136188 NCBI chr 1:174,393,387...174,410,977 JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP nimesulide results in decreased expression of LYZ2 mRNA CTD PMID:24136188 NCBI chr 7:54,792,715...54,798,060
Ensembl chr 7:54,792,716...54,798,011 		JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 decreases expression EXP nimesulide results in decreased expression of MACROD1 mRNA CTD PMID:24136188 NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348 		JBrowse link
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 increases expression EXP nimesulide results in increased expression of MAGMAS-PS1 mRNA CTD PMID:24136188 NCBI chr10:89,102,411...89,102,931 JBrowse link
G Magoh mago homolog, exon junction complex subunit increases expression EXP nimesulide results in increased expression of MAGOH mRNA CTD PMID:24136188 NCBI chr 5:127,868,044...127,875,423
Ensembl chr 5:127,868,055...127,875,384 		JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 increases expression EXP nimesulide results in increased expression of MALSU1 mRNA CTD PMID:24136188 NCBI chr 4:79,381,963...79,390,786
Ensembl chr 4:79,374,393...79,411,608 		JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 decreases expression EXP nimesulide results in decreased expression of MAN2B1 mRNA CTD PMID:24136188 NCBI chr19:39,959,964...39,979,299
Ensembl chr19:39,959,965...39,979,246 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor increases expression EXP nimesulide results in increased expression of MANF mRNA CTD PMID:24136188 NCBI chr 8:116,427,053...116,430,259
Ensembl chr 8:116,427,048...116,429,910 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression EXP nimesulide results in increased expression of MAP1LC3B mRNA CTD PMID:24136188 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression EXP nimesulide results in increased expression of MAP2K3 mRNA CTD PMID:24136188 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased phosphorylation of MAPK1 protein] CTD PMID:16376453 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased phosphorylation of MAPK3 protein] CTD PMID:16376453 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 decreases expression EXP nimesulide results in decreased expression of MAPK9 mRNA CTD PMID:24136188 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 decreases expression EXP nimesulide results in decreased expression of MAPKAPK2 mRNA CTD PMID:24136188 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 increases expression EXP nimesulide results in increased expression of MARCHF5 mRNA CTD PMID:24136188 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:244,343,630...244,366,462 		JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 increases expression EXP nimesulide results in increased expression of MARCHF6 mRNA CTD PMID:24136188 NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792 		JBrowse link
G Marcksl1 MARCKS-like 1 decreases expression EXP nimesulide results in decreased expression of MARCKSL1 mRNA CTD PMID:24136188 NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417 		JBrowse link
G Masp1 MBL associated serine protease 1 decreases expression EXP nimesulide results in decreased expression of MASP1 mRNA CTD PMID:24136188 NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470 		JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 increases expression EXP nimesulide results in increased expression of MBD3 mRNA CTD PMID:24136188 NCBI chr 7:9,961,053...9,970,845
Ensembl chr 7:9,963,797...9,970,265 		JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression EXP nimesulide results in decreased expression of MBL2 mRNA CTD PMID:24136188 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Mbtd1 mbt domain containing 1 decreases expression EXP nimesulide results in decreased expression of MBTD1 mRNA CTD PMID:24136188 NCBI chr10:79,336,041...79,392,315
Ensembl chr10:79,335,235...79,392,315 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 decreases expression EXP nimesulide results in decreased expression of MCCC2 mRNA CTD PMID:24136188 NCBI chr 2:33,039,044...33,110,092
Ensembl chr 2:33,039,045...33,110,299 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression EXP nimesulide results in increased expression of MCM4 mRNA CTD PMID:24136188 NCBI chr11:98,762,599...98,776,300
Ensembl chr11:98,762,634...98,776,536 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP nimesulide results in increased expression of MCM6 mRNA CTD PMID:24136188 NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 increases expression EXP nimesulide results in increased expression of MCM7 mRNA CTD PMID:24136188 NCBI chr12:22,155,921...22,163,320
Ensembl chr12:22,155,921...22,163,771 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 increases expression EXP nimesulide results in increased expression of MCOLN1 mRNA CTD PMID:24136188 NCBI chr12:6,357,851...6,372,151
Ensembl chr12:6,357,807...6,372,151 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP nimesulide results in increased expression of MDM2 mRNA CTD PMID:24136188 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Med29 mediator complex subunit 29 increases expression EXP nimesulide results in increased expression of MED29 mRNA CTD PMID:24136188 NCBI chr 1:92,805,505...92,810,908 JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO nimesulide results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression EXP nimesulide results in decreased expression of MFGE8 mRNA CTD PMID:24136188 NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431 		JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP nimesulide results in decreased expression of MGAT4B mRNA CTD PMID:24136188 NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309 		JBrowse link
G Mgll monoglyceride lipase increases expression EXP nimesulide results in increased expression of MGLL mRNA CTD PMID:24136188 NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression EXP nimesulide results in increased expression of MGST2 mRNA CTD PMID:24136188 NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 decreases expression EXP nimesulide results in decreased expression of MGST3 mRNA CTD PMID:24136188 NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 increases expression EXP nimesulide results in increased expression of MIA3 mRNA CTD PMID:24136188 NCBI chr13:97,502,040...97,547,155
Ensembl chr13:97,494,275...97,543,587 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 decreases expression EXP nimesulide results in decreased expression of MID1IP1 mRNA CTD PMID:24136188 NCBI chr  X:14,733,539...14,735,859
Ensembl chr  X:14,732,830...14,739,079 		JBrowse link
G Mix23 mitochondrial matrix import factor 23 increases expression EXP nimesulide results in increased expression of MIX23 mRNA CTD PMID:24136188 NCBI chr11:78,166,038...78,186,323
Ensembl chr11:78,166,038...78,186,323 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP nimesulide inhibits the reaction [[Sulfadimethoxine co-treated with diisopropanolnitrosamine] results in increased expression of MKI67 protein] CTD PMID:22387750 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mlec malectin increases expression EXP nimesulide results in increased expression of MLEC mRNA CTD PMID:24136188 NCBI chr12:47,118,918...47,133,598
Ensembl chr12:47,118,855...47,130,064 		JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression EXP nimesulide results in increased expression of MLYCD mRNA CTD PMID:24136188 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 increases expression EXP nimesulide results in increased expression of MMGT1 mRNA CTD PMID:24136188 NCBI chr  X:139,445,834...139,458,169
Ensembl chr  X:139,445,834...139,458,169 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO nimesulide results in decreased expression of MMP9 mRNA; nimesulide results in decreased expression of MMP9 protein CTD PMID:21176579 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 increases expression EXP nimesulide results in increased expression of MOCS2 mRNA CTD PMID:24136188 NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394 		JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase increases expression EXP nimesulide results in increased expression of MOGS mRNA CTD PMID:24136188 NCBI chr 4:117,179,335...117,182,738
Ensembl chr 4:117,179,335...117,182,744 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 increases expression EXP nimesulide results in increased expression of MPC2 mRNA CTD PMID:24136188 NCBI chr13:80,261,143...80,280,668
Ensembl chr13:80,259,727...80,280,668 		JBrowse link
G Mpo myeloperoxidase decreases activity
multiple interactions 		EXP
ISO 		nimesulide results in decreased activity of MPO
nimesulide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]
[[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite 		CTD PMID:11137876 PMID:11996850 PMID:20939553 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 decreases expression EXP nimesulide results in decreased expression of MPP1 mRNA CTD PMID:24136188
G Mrc1 mannose receptor, C type 1 decreases expression EXP nimesulide results in decreased expression of MRC1 mRNA CTD PMID:24136188 NCBI chr17:82,157,725...82,239,411
Ensembl chr17:82,157,705...82,239,410 		JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 increases expression EXP nimesulide results in increased expression of MRPL12 mRNA CTD PMID:24136188 NCBI chr10:106,256,746...106,261,249
Ensembl chr10:106,256,547...106,263,088 		JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 increases expression EXP nimesulide results in increased expression of MRPL14 mRNA CTD PMID:24136188 NCBI chr 9:22,800,286...22,812,711
Ensembl chr 9:22,795,744...22,812,855 		JBrowse link
G Mrpl17 mitochondrial ribosomal protein L17 increases expression EXP nimesulide results in increased expression of MRPL17 mRNA CTD PMID:24136188 NCBI chr 1:169,574,010...169,575,699
Ensembl chr 1:169,574,010...169,575,818 		JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 increases expression EXP nimesulide results in increased expression of MRPL18 mRNA CTD PMID:24136188 NCBI chr 1:50,384,951...50,389,769
Ensembl chr 1:50,384,367...50,389,763 		JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 increases expression EXP nimesulide results in increased expression of MRPL19 mRNA CTD PMID:24136188 NCBI chr 4:116,079,654...116,083,883
Ensembl chr 4:116,079,654...116,083,883 		JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 increases expression EXP nimesulide results in increased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:171,690,664...171,695,728
Ensembl chr 5:171,691,198...171,695,728 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 increases expression EXP nimesulide results in increased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:42,843,165...42,856,243
Ensembl chr10:42,843,222...42,856,227 		JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 increases expression EXP nimesulide results in increased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:207,116,930...207,124,702
Ensembl chr 1:207,116,462...207,124,699 		JBrowse link
G Mrpl24 mitochondrial ribosomal protein L24 increases expression EXP nimesulide results in increased expression of MRPL24 mRNA CTD PMID:24136188 NCBI chr 2:175,680,872...175,687,107
Ensembl chr 2:175,681,070...175,688,660 		JBrowse link
G Mrpl34 mitochondrial ribosomal protein L34 increases expression EXP nimesulide results in increased expression of MRPL34 mRNA CTD PMID:24136188 NCBI chr16:18,186,447...18,187,182
Ensembl chr16:18,185,306...18,187,181 		JBrowse link
G Mrpl38 mitochondrial ribosomal protein L38 increases expression EXP nimesulide results in increased expression of MRPL38 mRNA CTD PMID:24136188 NCBI chr10:101,864,242...101,871,048
Ensembl chr10:101,863,318...101,871,048 		JBrowse link
G Mrpl49 mitochondrial ribosomal protein L49 increases expression EXP nimesulide results in increased expression of MRPL49 mRNA CTD PMID:24136188 NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888 		JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 increases expression EXP nimesulide results in increased expression of MRPL50 mRNA CTD PMID:24136188 NCBI chr 5:68,662,933...68,668,087
Ensembl chr 5:68,662,939...68,669,748 		JBrowse link
G Mrpl53 mitochondrial ribosomal protein L53 increases expression EXP nimesulide results in increased expression of MRPL53 mRNA CTD PMID:24136188 NCBI chr 4:117,173,043...117,173,933 JBrowse link
G Mrpl55 mitochondrial ribosomal protein L55 increases expression EXP nimesulide results in increased expression of MRPL55 mRNA CTD PMID:24136188 NCBI chr10:44,488,252...44,491,401
Ensembl chr10:44,488,244...44,491,401 		JBrowse link
G Mrps14 mitochondrial ribosomal protein S14 increases expression EXP nimesulide results in increased expression of MRPS14 mRNA CTD PMID:24136188 NCBI chr13:74,962,597...74,968,344
Ensembl chr13:74,962,515...74,970,975 		JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B increases expression EXP nimesulide results in increased expression of MRPS18B mRNA CTD PMID:24136188 NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065 		JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C increases expression EXP nimesulide results in increased expression of MRPS18C mRNA CTD PMID:24136188 NCBI chr14:9,116,688...9,122,943 JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 increases expression EXP nimesulide results in increased expression of MRPS27 mRNA CTD PMID:24136188 NCBI chr 2:32,474,178...32,542,741
Ensembl chr 2:32,473,965...32,542,738 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 increases expression EXP nimesulide results in increased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:69,563,501...69,572,317
Ensembl chr 4:69,563,503...69,572,177 		JBrowse link
G Mrps34 mitochondrial ribosomal protein S34 increases expression EXP nimesulide results in increased expression of MRPS34 mRNA CTD PMID:24136188 NCBI chr10:14,420,543...14,421,674
Ensembl chr10:14,408,136...14,421,771 		JBrowse link
G Mrps35 mitochondrial ribosomal protein S35 increases expression EXP nimesulide results in increased expression of MRPS35 mRNA CTD PMID:24136188 NCBI chr 4:181,688,715...181,719,403
Ensembl chr 4:181,688,614...181,730,118 		JBrowse link
G Mrps7 mitochondrial ribosomal protein S7 increases expression EXP nimesulide results in increased expression of MRPS7 mRNA CTD PMID:24136188 NCBI chr10:101,342,642...101,345,790
Ensembl chr10:101,342,421...101,346,082 		JBrowse link
G Mrto4 MRT4 homolog, ribosome maturation factor increases expression EXP nimesulide results in increased expression of MRTO4 mRNA CTD PMID:24136188 NCBI chr 5:156,884,985...156,891,738
Ensembl chr 5:156,884,985...156,891,738 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Nimesulide decreases expression of MT-CO2 mRNA and protein in esophagus squamous epithelium RGD PMID:25724470 RGD:127285656 NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression EXP nimesulide results in decreased expression of MTARC1 mRNA CTD PMID:24136188 NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252 		JBrowse link
G Mtx1 Metaxin 1 increases expression EXP nimesulide results in increased expression of MTX1 mRNA CTD PMID:24136188 NCBI chr 2:176,913,225...176,919,148
Ensembl chr 2:176,913,225...176,918,824 		JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP nimesulide results in decreased expression of MUG1 mRNA CTD PMID:24136188 NCBI chr 4:156,748,351...156,802,132 JBrowse link
G Mydgf myeloid-derived growth factor increases expression EXP nimesulide results in increased expression of MYDGF mRNA CTD PMID:24136188 NCBI chr 9:1,086,825...1,095,968
Ensembl chr 9:1,086,825...1,095,968 		JBrowse link
G Myh9 myosin, heavy chain 9 decreases expression EXP nimesulide results in decreased expression of MYH9 mRNA CTD PMID:24136188 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963 		JBrowse link
G Myo1b myosin Ib decreases expression EXP nimesulide results in decreased expression of MYO1B mRNA CTD PMID:24136188 NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328 		JBrowse link
G Myo1d myosin ID decreases expression EXP nimesulide results in decreased expression of MYO1D mRNA CTD PMID:24136188 NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958 		JBrowse link
G Myo1g myosin IG increases expression EXP nimesulide results in increased expression of MYO1G mRNA CTD PMID:24136188 NCBI chr14:85,600,619...85,615,760
Ensembl chr14:85,600,619...85,615,760 		JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit increases expression EXP nimesulide results in increased expression of NAA20 mRNA CTD PMID:24136188 NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916 		JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression EXP nimesulide results in increased expression of NAA38 mRNA CTD PMID:24136188 NCBI chr10:54,588,304...54,617,715
Ensembl chr10:54,592,990...54,617,715 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit increases expression EXP nimesulide results in increased expression of NAA50 mRNA CTD PMID:24136188 NCBI chr11:70,044,281...70,066,754
Ensembl chr11:70,044,281...70,066,754 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP nimesulide results in increased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP nimesulide results in increased expression of NAP1L1 mRNA CTD PMID:24136188 NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104 		JBrowse link
G Nat8 N-acetyltransferase 8 increases expression EXP nimesulide results in increased expression of NAT8 mRNA CTD PMID:24136188 NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159 		JBrowse link
G Ndrg2 NDRG family member 2 decreases expression EXP nimesulide results in decreased expression of NDRG2 mRNA CTD PMID:24136188 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125 		JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP nimesulide results in increased expression of NDUFA5 mRNA CTD PMID:24136188 NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP nimesulide results in increased expression of NDUFA7 mRNA CTD PMID:24136188 NCBI chr 7:15,311,446...15,324,226
Ensembl chr 7:15,311,286...15,334,138 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP nimesulide results in increased expression of NDUFAB1 mRNA CTD PMID:24136188 NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:186,057,113...186,089,373 		JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP nimesulide results in increased expression of NDUFAF4 mRNA CTD PMID:24136188 NCBI chr 5:43,401,795...43,406,967 JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 increases expression EXP nimesulide results in increased expression of NDUFC2 mRNA CTD PMID:24136188 NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP nimesulide results in decreased expression of NECTIN3 mRNA CTD PMID:24136188 NCBI chr11:67,825,296...67,931,999
Ensembl chr11:67,827,137...67,871,383 		JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier increases expression EXP nimesulide results in increased expression of NEDD8 mRNA CTD PMID:24136188 NCBI chr15:33,123,505...33,135,522
Ensembl chr15:33,123,505...33,135,522 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
affects localization 		ISO
EXP 		Sulfaphenazole affects the reaction [nimesulide affects the localization of NFE2L2 protein]
nimesulide results in decreased expression of NFE2L2 mRNA
NFE2L2 mutant form inhibits the reaction [nimesulide results in increased expression of NQO1] 		CTD PMID:20405857 PMID:24136188 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfia nuclear factor I/A decreases expression EXP nimesulide results in decreased expression of NFIA mRNA CTD PMID:24136188 NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395 		JBrowse link
G Nfib nuclear factor I/B decreases expression EXP nimesulide results in decreased expression of NFIB mRNA CTD PMID:24136188 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression EXP nimesulide results in decreased expression of NFIL3 mRNA CTD PMID:24136188 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP nimesulide inhibits the reaction [NGF protein results in increased secretion of Dinoprostone]; nimesulide inhibits the reaction [NGF protein results in increased secretion of TAC1 protein]; nimesulide inhibits the reaction [NGF results in increased expression of TAC1 mRNA] CTD PMID:21811393 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein increases expression EXP nimesulide results in increased expression of NHP2 mRNA CTD PMID:24136188 NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354 		JBrowse link
G Nid1 nidogen 1 decreases expression EXP nimesulide results in decreased expression of NID1 mRNA CTD PMID:24136188 NCBI chr17:93,069,013...93,142,416
Ensembl chr17:93,069,278...93,142,386 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 increases expression EXP nimesulide results in increased expression of NIFK mRNA CTD PMID:24136188 NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561 		JBrowse link
G Nit2 nitrilase family, member 2 decreases expression EXP nimesulide results in decreased expression of NIT2 mRNA CTD PMID:24136188 NCBI chr11:56,832,957...56,844,142
Ensembl chr11:56,832,558...56,844,141 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP nimesulide results in increased expression of NME1 mRNA CTD PMID:24136188 NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression EXP nimesulide results in decreased expression of NNT mRNA CTD PMID:24136188 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression EXP nimesulide results in increased expression of NOP56 mRNA CTD PMID:24136188 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
decreases expression 		ISO
EXP 		nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]; nimesulide inhibits the reaction [bepafant inhibits the reaction [[Mycoplasma arthritidis mitogen results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]]
nimesulide results in increased expression of NOS2 mRNA; nimesulide results in increased expression of NOS2 protein
nimesulide results in decreased expression of NOS2
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; [camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of NOS2 protein]; nimesulide inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NOS2 protein]; Silymarin inhibits the reaction [nimesulide results in increased expression of NOS2 mRNA]; Silymarin inhibits the reaction [nimesulide results in increased expression of NOS2 protein] 		CTD PMID:15135310 PMID:15242784 PMID:15892897 PMID:22107987 PMID:22509279 More... NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Notch2 notch receptor 2 decreases expression EXP nimesulide results in decreased expression of NOTCH2 mRNA CTD PMID:24136188 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 decreases expression EXP nimesulide results in decreased expression of NPC2 mRNA CTD PMID:24136188 NCBI chr 6:110,128,325...110,149,245
Ensembl chr 6:110,128,325...110,150,004 		JBrowse link
G Npepl1 aminopeptidase-like 1 increases expression EXP nimesulide results in increased expression of NPEPL1 mRNA CTD PMID:24136188 NCBI chr 3:183,312,185...183,324,744
Ensembl chr 3:183,312,185...183,324,744 		JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP nimesulide results in increased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:135,413,927...135,469,505 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression EXP nimesulide results in increased expression of NPLOC4 mRNA CTD PMID:24136188 NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression 		ISO
EXP 		NFE2L2 mutant form inhibits the reaction [nimesulide results in increased expression of NQO1]
nimesulide results in increased expression of NQO1 mRNA 		CTD PMID:20405857 PMID:24136188 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP nimesulide results in increased expression of NR1D2 mRNA CTD PMID:24136188 NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP nimesulide results in decreased expression of NR1H4 mRNA CTD PMID:24136188 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP nimesulide results in decreased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP nimesulide results in decreased expression of NREP mRNA CTD PMID:24136188 NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL decreases expression EXP nimesulide results in decreased expression of NSDHL mRNA CTD PMID:24136188 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component increases expression EXP nimesulide results in increased expression of NSMCE1 mRNA CTD PMID:24136188 NCBI chr 1:189,462,801...189,489,188
Ensembl chr 1:189,462,677...189,491,432 		JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 increases expression EXP nimesulide results in increased expression of NSUN2 mRNA CTD PMID:24136188 NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:35,490,583...35,514,306 		JBrowse link
G Nt5e 5' nucleotidase, ecto decreases expression
multiple interactions 		EXP
ISO 		nimesulide results in decreased expression of NT5E mRNA
NT5E protein affects the reaction [nimesulide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased abundance of Nitrites]] 		CTD PMID:24136188 PMID:27188793 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645 		JBrowse link
G Nubp2 NUBP iron-sulfur cluster assembly factor 2 increases expression EXP nimesulide results in increased expression of NUBP2 mRNA CTD PMID:24136188 NCBI chr10:14,407,743...14,411,428
Ensembl chr10:14,407,745...14,411,600 		JBrowse link
G Nudc nuclear distribution C, dynein complex regulator increases expression EXP nimesulide results in increased expression of NUDC mRNA CTD PMID:24136188 NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260 		JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP nimesulide results in increased expression of NUDT4 mRNA CTD PMID:24136188 NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491 		JBrowse link
G Nudt7 nudix hydrolase 7 increases expression EXP nimesulide results in increased expression of NUDT7 mRNA CTD PMID:24136188 NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit increases expression EXP nimesulide results in increased expression of NUS1 mRNA CTD PMID:24136188 NCBI chr20:32,354,519...32,381,265
Ensembl chr20:32,354,439...32,381,264 		JBrowse link
G Nutf2 nuclear transport factor 2 increases expression EXP nimesulide results in increased expression of NUTF2 mRNA CTD PMID:24136188 NCBI chr19:50,662,168...50,683,457
Ensembl chr19:50,662,394...50,683,454 		JBrowse link
G Oaf out at first homolog decreases expression EXP nimesulide results in decreased expression of OAF mRNA CTD PMID:24136188 NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285 		JBrowse link
G Oat ornithine aminotransferase decreases expression EXP nimesulide results in decreased expression of OAT mRNA CTD PMID:24136188 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Obp3 alpha-2u globulin PGCL4 increases expression EXP nimesulide results in increased expression of OBP3 mRNA CTD PMID:24136188 NCBI chr 5:79,637,234...79,640,810
Ensembl chr 5:79,637,234...79,640,675 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP nimesulide results in increased expression of ODC1 mRNA CTD PMID:24136188 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression
multiple interactions 		EXP nimesulide results in increased expression of OGG1 protein
[camphene co-treated with geraniol] inhibits the reaction [nimesulide results in increased expression of OGG1 protein]; Silymarin inhibits the reaction [nimesulide results in increased expression of OGG1 protein] 		CTD PMID:22509279 NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604 		JBrowse link
G Orm1 orosomucoid 1 increases expression EXP nimesulide results in increased expression of ORM1 mRNA CTD PMID:24136188 NCBI chr 5:81,788,509...81,791,661
Ensembl chr 5:81,788,395...81,791,667 		JBrowse link
G Osbpl11 oxysterol binding protein-like 11 decreases expression EXP nimesulide results in decreased expression of OSBPL11 mRNA CTD PMID:24136188 NCBI chr11:81,038,759...81,121,887
Ensembl chr11:81,038,985...81,101,299 		JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit increases expression EXP nimesulide results in increased expression of OSTC mRNA CTD PMID:24136188 NCBI chr 2:221,924,727...221,940,253
Ensembl chr 2:221,874,948...221,940,267 		JBrowse link
G Otc ornithine transcarbamylase decreases expression EXP nimesulide results in decreased expression of OTC mRNA CTD PMID:24136188 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:15,126,358...15,239,555 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 increases expression EXP nimesulide results in increased expression of OTUB1 mRNA CTD PMID:24136188 NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679 		JBrowse link
G Ovca2 OVCA2 serine hydrolase domain containing increases expression EXP nimesulide results in increased expression of OVCA2 mRNA CTD PMID:24136188 NCBI chr10:60,524,385...60,527,547
Ensembl chr10:60,522,026...60,527,536 		JBrowse link
G Oxnad1 oxidoreductase NAD-binding domain containing 1 increases expression EXP nimesulide results in increased expression of OXNAD1 mRNA CTD PMID:24136188 NCBI chr16:7,299,755...7,328,824
Ensembl chr16:7,299,755...7,328,824 		JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression EXP nimesulide results in increased expression of PA2G4 mRNA CTD PMID:24136188 NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases expression EXP nimesulide results in increased expression of PAICS mRNA CTD PMID:24136188 NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027 		JBrowse link
G Pald1 phosphatase domain containing, paladin 1 increases expression EXP nimesulide results in increased expression of PALD1 mRNA CTD PMID:24136188 NCBI chr20:29,812,650...29,877,733
Ensembl chr20:29,812,650...29,850,063 		JBrowse link
G Palmd palmdelphin decreases expression EXP nimesulide results in decreased expression of PALMD mRNA CTD PMID:24136188 NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:207,574,249...207,626,239 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase decreases expression EXP nimesulide results in decreased expression of PAM mRNA CTD PMID:24136188 NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:105,445,929...105,719,285 		JBrowse link
G Paox polyamine oxidase increases expression EXP nimesulide results in increased expression of PAOX mRNA CTD PMID:24136188 NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression EXP nimesulide results in decreased expression of PAPSS2 mRNA CTD PMID:24136188 NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:239,867,574...239,952,616 		JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression EXP nimesulide results in decreased expression of PAQR9 mRNA CTD PMID:24136188 NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
increases expression 		ISO
EXP 		nimesulide results in increased cleavage of PARP1 protein
nimesulide results in increased expression of PARP1 mRNA 		CTD PMID:19360361 PMID:24136188 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pawr pro-apoptotic WT1 regulator increases expression ISO nimesulide results in increased expression of PAWR mRNA CTD PMID:10833474 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492 		JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP nimesulide results in increased expression of PBLD1 mRNA CTD PMID:24136188 NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 decreases expression EXP nimesulide results in decreased expression of PBXIP1 mRNA CTD PMID:24136188 NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:177,154,101...177,167,328 		JBrowse link
G Pc pyruvate carboxylase decreases expression EXP nimesulide results in decreased expression of PC mRNA CTD PMID:24136188 NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 decreases expression EXP nimesulide results in decreased expression of PCMTD1 mRNA CTD PMID:24136188 NCBI chr 5:17,071,629...17,143,803
Ensembl chr 5:17,071,629...17,142,010 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP nimesulide results in increased expression of PCNA mRNA CTD PMID:24136188 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcnx1 pecanex 1 decreases expression EXP nimesulide results in decreased expression of PCNX1 mRNA CTD PMID:24136188 NCBI chr 6:107,296,704...107,433,576
Ensembl chr 6:107,296,792...107,432,452 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression EXP nimesulide results in decreased expression of PDCD4 mRNA CTD PMID:24136188 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP nimesulide results in decreased expression of PDE4B mRNA CTD PMID:24136188 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP nimesulide results in increased expression of PDIA4 mRNA CTD PMID:24136188 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:78,134,144...78,153,191 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 decreases expression EXP nimesulide results in decreased expression of PDK2 mRNA CTD PMID:24136188 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP nimesulide results in decreased expression of PDLIM1 mRNA CTD PMID:24136188 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase increases expression EXP nimesulide results in increased expression of PECR mRNA CTD PMID:24136188 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806 		JBrowse link
G Pef1 penta-EF hand domain containing 1 increases expression EXP nimesulide results in increased expression of PEF1 mRNA CTD PMID:24136188 NCBI chr 5:147,735,973...147,759,239
Ensembl chr 5:147,735,976...147,761,092 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor increases expression EXP nimesulide results in increased expression of PELO mRNA CTD PMID:24136188 NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression EXP nimesulide results in decreased expression of PEMT mRNA CTD PMID:24136188 NCBI chr10:45,275,434...45,349,651
Ensembl chr10:45,275,412...45,420,037 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression EXP nimesulide results in increased expression of PEX11A mRNA CTD PMID:24136188 NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:143,089,410...143,096,645 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 increases expression EXP nimesulide results in increased expression of PEX7 mRNA CTD PMID:24136188 NCBI chr 1:16,402,319...16,466,304
Ensembl chr 1:16,402,320...16,466,366 		JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression EXP nimesulide results in increased expression of PFDN5 mRNA CTD PMID:24136188 NCBI chr 7:135,330,364...135,335,102
Ensembl chr 7:135,330,172...135,335,099 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression EXP nimesulide results in increased expression of PGRMC1 mRNA CTD PMID:24136188 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805 		JBrowse link
G Phb1 prohibitin 1 increases expression EXP nimesulide results in increased expression of PHB1 mRNA CTD PMID:24136188 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 decreases expression EXP nimesulide results in decreased expression of PHF20L1 mRNA CTD PMID:24136188 NCBI chr 7:100,219,598...100,285,580
Ensembl chr 7:100,219,639...100,285,580 		JBrowse link
G Phf5a PHD finger protein 5A increases expression EXP nimesulide results in increased expression of PHF5A mRNA CTD PMID:24136188 NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression EXP nimesulide results in decreased expression of PHLDB2 mRNA CTD PMID:24136188 NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734 		JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta increases expression EXP nimesulide results in increased expression of PI4K2B mRNA CTD PMID:24136188 NCBI chr14:62,434,589...62,461,507
Ensembl chr14:62,424,511...62,461,446 		JBrowse link
G Pigx phosphatidylinositol glycan anchor biosynthesis, class X increases expression EXP nimesulide results in increased expression of PIGX mRNA CTD PMID:24136188 NCBI chr11:82,192,125...82,208,062
Ensembl chr11:82,192,092...82,208,061 		JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase increases expression EXP nimesulide results in increased expression of PIM3 mRNA CTD PMID:24136188 NCBI chr 7:121,822,076...121,836,257
Ensembl chr 7:121,832,742...121,836,259 		JBrowse link
G Pir pirin increases expression EXP nimesulide results in increased expression of PIR mRNA CTD PMID:24136188 NCBI chr  X:33,740,428...33,851,049
Ensembl chr  X:33,740,429...33,851,049 		JBrowse link
G Pithd1 PITH domain containing 1 increases expression EXP nimesulide results in increased expression of PITHD1 mRNA CTD PMID:24136188 NCBI chr 5:153,489,529...153,500,025
Ensembl chr 5:153,489,529...153,500,261 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic decreases expression EXP nimesulide results in decreased expression of PKDCC mRNA CTD PMID:24136188 NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP nimesulide results in decreased expression of PKLR mRNA CTD PMID:24136188 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP nimesulide results in increased expression of PLA2G12A mRNA CTD PMID:24136188 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Plaa phospholipase A2, activating protein increases expression EXP nimesulide results in increased expression of PLAA mRNA CTD PMID:24136188 NCBI chr 5:114,544,327...114,576,023
Ensembl chr 5:114,544,325...114,576,109 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 decreases expression EXP nimesulide results in decreased expression of PLAAT3 mRNA CTD PMID:24136188 NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763 		JBrowse link
G Plbd1 phospholipase B domain containing 1 decreases expression EXP nimesulide results in decreased expression of PLBD1 mRNA CTD PMID:24136188 NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488 		JBrowse link
G Plin2 perilipin 2 increases expression ISO nimesulide results in increased expression of PLIN2 mRNA CTD PMID:19415698 NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878 		JBrowse link
G Plpp2 phospholipid phosphatase 2 increases expression EXP nimesulide results in increased expression of PLPP2 mRNA CTD PMID:24136188 NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627 		JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression EXP nimesulide results in decreased expression of PLPP3 mRNA CTD PMID:24136188 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Plpp5 phospholipid phosphatase 5 increases expression EXP nimesulide results in increased expression of PLPP5 mRNA CTD PMID:24136188 NCBI chr16:73,052,204...73,056,609
Ensembl chr16:73,052,204...73,056,643 		JBrowse link
G Pltp phospholipid transfer protein decreases expression EXP nimesulide results in decreased expression of PLTP mRNA CTD PMID:24136188 NCBI chr 3:173,994,162...174,011,982
Ensembl chr 3:173,994,162...174,012,505 		JBrowse link
G Plxna2 plexin A2 decreases expression EXP nimesulide results in decreased expression of PLXNA2 mRNA CTD PMID:24136188 NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453 		JBrowse link
G Pnisr PNN interacting serine and arginine rich protein decreases expression EXP nimesulide results in decreased expression of PNISR mRNA CTD PMID:24136188 NCBI chr 5:40,190,214...40,219,619
Ensembl chr 5:40,192,735...40,219,611 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP nimesulide results in increased expression of PNPLA2 mRNA CTD PMID:24136188 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359 		JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression EXP nimesulide results in increased expression of PNPLA7 mRNA CTD PMID:24136188 NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 increases expression EXP nimesulide results in increased expression of PNPLA8 mRNA CTD PMID:24136188 NCBI chr 6:67,056,783...67,118,714
Ensembl chr 6:67,056,697...67,120,512 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 decreases expression EXP nimesulide results in decreased expression of PNRC1 mRNA CTD PMID:24136188 NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression EXP nimesulide results in increased expression of POLD4 mRNA CTD PMID:24136188 NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860 		JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit increases expression EXP nimesulide results in increased expression of POLE3 mRNA CTD PMID:24136188 NCBI chr 5:80,989,508...80,992,742
Ensembl chr 5:80,989,511...80,992,742
Ensembl chr 7:80,989,511...80,992,742 		JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit increases expression EXP nimesulide results in increased expression of POLE4 mRNA CTD PMID:24136188 NCBI chr 4:116,723,040...116,728,873
Ensembl chr 4:116,716,719...116,728,851 		JBrowse link
G Polr2g RNA polymerase II subunit G increases expression