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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acyclic carotene
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Accession:CHEBI:35162 term browser browse the term
Synonyms:related_synonym: acyclic carotenes



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all-trans-phytoene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:43,511,685...43,904,454 JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240 JBrowse link
all-trans-phytofluene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:43,511,685...43,904,454 JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240 JBrowse link
lycopene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions EXP Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein] CTD PMID:32153214 NCBI chr10:91,410,129...91,430,246 JBrowse link
G Ache acetylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] CTD PMID:22192907 PMID:26900785 NCBI chr12:25,042,882...25,050,608 JBrowse link
G Acvr2b activin A receptor type 2B decreases expression EXP Lycopene results in decreased expression of SCGB2A2 mRNA CTD PMID:15084515 NCBI chr 8:128,016,589...128,056,193 JBrowse link
G Add1 adducin 1 decreases expression ISO lycopene results in decreased expression of ADD1 mRNA CTD PMID:16886892 NCBI chr14:80,333,242...80,401,641 JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] CTD PMID:22429818 NCBI chr20:4,152,758...4,155,956 JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression
multiple interactions
ISO lycopene results in decreased expression of AHR mRNA
[Lycopene co-treated with Atrazine] results in increased expression of AHR mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of AHR protein]
CTD PMID:16886892 PMID:36216167 PMID:36403809 NCBI chr 6:57,961,423...57,998,901 JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 NCBI chr20:3,651,435...3,657,341 JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO lycopene results in decreased phosphorylation of AKT1 protein CTD PMID:17337101 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO
EXP
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein]
lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
CTD PMID:17516994 PMID:25682699 NCBI chr 5:80,977,562...80,987,901 JBrowse link
G Andpro androgen regulated protein decreases expression EXP lycopene results in decreased expression of ANDPRO mRNA CTD PMID:15084515 NCBI chr 3:157,171,739...157,178,262 JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of AQP1 mRNA] CTD PMID:33960999 NCBI chr 4:85,812,784...85,824,964 JBrowse link
G Aqp11 aquaporin 11 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP11 mRNA] CTD PMID:33960999 NCBI chr 1:161,457,752...161,467,918 JBrowse link
G Aqp2 aquaporin 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 protein] CTD PMID:33960999 NCBI chr 7:132,590,286...132,595,321 JBrowse link
G Aqp4 aquaporin 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP4 mRNA] CTD PMID:33960999 NCBI chr18:6,782,389...6,799,034 JBrowse link
G Aqp6 aquaporin 6 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP6 mRNA] CTD PMID:33960999 NCBI chr 7:132,611,069...132,614,004 JBrowse link
G Aqp7 aquaporin 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of AQP7 mRNA] CTD PMID:33960999 NCBI chr 5:60,968,495...60,982,618 JBrowse link
G Ar androgen receptor decreases expression ISO lycopene results in decreased expression of AR mRNA CTD PMID:16886892 NCBI chr  X:67,135,317...67,304,476 JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions
ISO Lycopene results in increased expression of ARNT mRNA
Lycopene inhibits the reaction [Atrazine results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT protein]
CTD PMID:36216167 PMID:36403809 NCBI chr 2:185,686,703...185,745,546 JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] CTD PMID:32544411 NCBI chr13:85,460,312...85,639,959 JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] CTD PMID:30360616 NCBI chr 2:23,843,695...24,133,459 JBrowse link
G Atg13 autophagy related 13 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] CTD PMID:30360616 NCBI chr 3:98,102,831...98,136,741 JBrowse link
G Atg14 autophagy related 14 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] CTD PMID:30360616 NCBI chr15:23,275,457...23,306,817 JBrowse link
G Atg16l1 autophagy related 16-like 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] CTD PMID:30360616 NCBI chr 9:95,869,839...95,905,354 JBrowse link
G Atg16l2 autophagy related 16-like 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] CTD PMID:30360616 NCBI chr 1:165,100,946...165,123,307 JBrowse link
G Atg2b autophagy related 2B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] CTD PMID:30360616 NCBI chr 6:130,286,979...130,357,109 JBrowse link
G Atg3 autophagy related 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] CTD PMID:30360616 NCBI chr11:69,130,948...69,159,280 JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] CTD PMID:30360616 NCBI chr  X:109,453,712...109,553,758 JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] CTD PMID:30360616 NCBI chr 9:101,729,772...101,761,456 JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] CTD PMID:30360616 NCBI chr 5:118,977,594...119,050,894 JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA]
[Glucose co-treated with Lycopene] results in increased expression of ATG5 mRNA
CTD PMID:30360616 PMID:38444079 NCBI chr20:49,380,835...49,471,826 JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] CTD PMID:30360616 NCBI chr 4:149,390,000...149,597,534 JBrowse link
G Atg9a autophagy related 9A multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] CTD PMID:30360616 NCBI chr 9:84,126,071...84,136,723 JBrowse link
G Atg9b autophagy related 9B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] CTD PMID:30360616 NCBI chr 4:11,678,548...11,686,097 JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 2:191,709,311...191,737,414 JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr13:87,261,964...87,286,911 JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] CTD PMID:26476475 NCBI chr 1:89,700,645...89,729,782 JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:87,216,139...87,252,155 JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr13:79,319,708...79,340,226 JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B2 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr10:54,817,473...54,823,708 JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] CTD PMID:26476475 NCBI chr 8:105,789,824...105,821,151 JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] CTD PMID:26476475 PMID:33960999 NCBI chr  X:121,952,923...121,974,146 JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] CTD PMID:27112537 NCBI chr 1:190,457,198...190,475,410 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A2 mRNA] CTD PMID:27112537 PMID:33960999 NCBI chr12:39,733,519...39,782,942 JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr10:58,079,710...58,111,279 JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2B1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 7:35,622,267...35,731,904 JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 4:148,450,207...148,763,653 JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr  X:156,367,582...156,464,085 JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:47,708,157...47,807,389 JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2C1 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr 8:114,913,551...115,034,706 JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] CTD PMID:26476475 PMID:27112537 PMID:33960999 NCBI chr19:64,662,729...64,719,998 JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO lycopene results in increased expression of BACH1 mRNA CTD PMID:16886892 NCBI chr11:40,425,721...40,461,118 JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAK1 protein] CTD PMID:36583613 NCBI chr20:5,102,334...5,111,615 JBrowse link
G Bap1 BRCA1 associated deubiquitinase 1 increases expression ISO lycopene results in increased expression of BAP1 mRNA CTD PMID:16886892 NCBI chr16:6,453,126...6,461,952 JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]
Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA]
CTD PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:36583613 NCBI chr 1:105,076,472...105,081,906 JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] CTD PMID:26900785 NCBI chr 2:160,607,289...160,699,760 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of BCL2 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA]
lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]
Lycopene results in increased expression of BCL2 mRNA
CTD PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 More... NCBI chr13:23,204,464...23,366,900 JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions ISO BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] CTD PMID:21935922 NCBI chr19:62,058,061...62,094,923 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO
EXP
Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]
Lycopene inhibits the reaction [bisphenol A results in decreased expression of BDNF protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein]
CTD PMID:28974442 PMID:32153214 PMID:32544411 NCBI chr 3:116,619,633...116,670,212 JBrowse link
G Becn1 beclin 1 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA]
[Glucose co-treated with Lycopene] results in increased expression of BECN1 mRNA
CTD PMID:30360616 PMID:38444079 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO lycopene results in decreased expression of BRAF protein CTD PMID:17337101 NCBI chr 4:69,329,772...69,476,931 JBrowse link
G C1qa complement C1q A chain decreases expression ISO lycopene results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:154,417,086...154,419,933 JBrowse link
G C4b complement C4B decreases expression ISO lycopene results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr20:4,201,979...4,216,292 JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] CTD PMID:33592256 NCBI chr 1:178,312,636...178,317,588 JBrowse link
G Casp1 caspase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP1 protein] CTD PMID:36610486 NCBI chr 8:10,746,338...10,882,295 JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP3 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
CTD PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32153214 More... NCBI chr16:52,395,539...52,413,794 JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression
EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP8 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
lycopene results in decreased expression of CASP8 mRNA
CTD PMID:16030430 PMID:16886892 PMID:38444079 NCBI chr 9:67,747,109...67,806,699 JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
[Glucose co-treated with Lycopene] results in increased expression of CASP9 mRNA; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
CTD PMID:27871895 PMID:38444079
G Cat catalase multiple interactions
increases expression
increases activity
decreases expression
EXP
ISO
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]
lycopene results in increased expression of CAT
lycopene results in increased activity of CAT protein
Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein]
Lycopene results in decreased expression of CAT mRNA
CTD PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 More... NCBI chr 3:110,297,340...110,329,526 JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL4 mRNA] CTD PMID:36583613 NCBI chr10:68,963,893...68,965,728 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL5 mRNA] CTD PMID:36583613 NCBI chr10:68,820,330...68,824,906 JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]
lycopene results in decreased expression of CCND1 protein
lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]
CTD PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 NCBI chr 1:209,518,288...209,527,986 JBrowse link
G Ccne1 cyclin E1 decreases expression
increases expression
ISO lycopene results in decreased expression of CCNE1 protein
lycopene results in increased expression of CCNE1 mRNA
CTD PMID:16886892 PMID:17337101 NCBI chr 1:99,918,672...99,927,986 JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression
multiple interactions
EXP Lycopene results in increased expression of CCS mRNA
[Glucose co-treated with Lycopene] results in increased expression of CCS mRNA
CTD PMID:38444079 NCBI chr 1:211,543,192...211,564,354 JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO lycopene results in decreased expression of CDK1 protein CTD PMID:17337101 NCBI chr20:19,265,252...19,280,456 JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO lycopene results in decreased expression of CDK4 protein CTD PMID:17337101 NCBI chr 7:64,771,453...64,774,891 JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO lycopene results in decreased expression of CDK5 protein CTD PMID:17337101 NCBI chr 4:11,647,098...11,651,606 JBrowse link
G Cdk7 cyclin-dependent kinase 7 decreases expression ISO lycopene results in decreased expression of CDK7 protein CTD PMID:17337101 NCBI chr 2:33,574,623...33,599,485 JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO lycopene results in decreased expression of CDK9 protein CTD PMID:17337101 NCBI chr 3:36,394,168...36,399,016 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] CTD PMID:16565789 NCBI chr20:7,150,820...7,161,373 JBrowse link
G Cgas cyclic GMP-AMP synthase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS protein] CTD PMID:36583613 NCBI chr 8:88,172,559...88,187,538 JBrowse link
G Chga chromogranin A increases expression ISO lycopene results in increased expression of CHGA mRNA CTD PMID:16886892 NCBI chr 6:127,460,895...127,472,238 JBrowse link
G Chgb chromogranin B decreases expression ISO lycopene results in decreased expression of CHGB mRNA CTD PMID:16886892 NCBI chr 3:140,496,712...140,510,057 JBrowse link
G Ckb creatine kinase B multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] CTD PMID:26900785 NCBI chr 6:136,550,583...136,553,464 JBrowse link
G Crb1 crumbs cell polarity complex component 1 decreases expression ISO lycopene results in decreased expression of CRB1 mRNA CTD PMID:16886892 NCBI chr13:53,352,932...53,540,019 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases expression
EXP Lycopene inhibits the reaction [bisphenol A results in decreased expression of CREB1 protein]
Lycopene results in increased expression of CREB1 protein
CTD PMID:32153214 NCBI chr 9:73,397,333...73,466,339 JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CSF2 mRNA] CTD PMID:36583613 NCBI chr10:38,887,692...38,889,673 JBrowse link
G Ctss cathepsin S decreases expression ISO lycopene results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:185,775,316...185,803,440 JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 protein] CTD PMID:36583613 NCBI chr14:15,989,066...15,991,263 JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO lycopene results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr17:8,323,150...8,331,176 JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL2 mRNA] CTD PMID:36583613 NCBI chr14:17,465,210...17,467,255 JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] CTD PMID:26775023 NCBI chr18:80,487,923...80,520,544 JBrowse link
G Cygb cytoglobin increases expression EXP Lycopene results in increased expression of CYGB mRNA CTD PMID:38444079 NCBI chr10:102,376,506...102,386,272 JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] CTD PMID:19071209 NCBI chr 8:67,318,665...67,330,196 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO lycopene results in decreased activity of CYP1A1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 protein]
CTD PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 NCBI chr 8:66,991,940...66,998,014 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO [Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 protein]
Lycopene results in increased expression of CYP1A2 mRNA
CTD PMID:26775023 PMID:36216167 PMID:36403809 NCBI chr 8:66,971,261...66,978,149 JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
increases expression
ISO lycopene results in decreased activity of CYP1B1 protein
[Lycopene co-treated with Atrazine] results in increased expression of CYP1B1 mRNA; Lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 protein]
Lycopene results in increased expression of CYP1B1 mRNA
CTD PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 NCBI chr 6:21,093,927...21,103,091 JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of CYP2A4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2A4 mRNA] CTD PMID:26775023 PMID:36216167 NCBI chr 1:91,299,584...91,307,650 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO Lycopene promotes the reaction [Atrazine results in increased expression of CYP2B10 mRNA] CTD PMID:36216167 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO Lycopene affects the reaction [Atrazine results in increased expression of CYP2C29 mRNA] CTD PMID:36216167 NCBI chr 1:247,879,058...247,916,804 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 protein] CTD PMID:26775023 PMID:36216167 PMID:36403809 NCBI chr 1:205,269,967...205,280,365 JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2F2 mRNA] CTD PMID:36216167 NCBI chr 1:91,543,768...91,557,553 JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases activity ISO Lycopene results in increased activity of CYP3A4 protein CTD PMID:16632523 NCBI chr12:14,321,771...14,343,886 JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] CTD PMID:36216167 NCBI chr12:21,919,955...21,960,160 JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4V3 mRNA]
Lycopene results in increased expression of CYP4V3 mRNA
CTD PMID:36216167 NCBI chr16:53,650,978...53,675,916 JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] CTD PMID:26775023 NCBI chr 2:102,419,011...102,586,047 JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO lycopene results in increased expression of DDB2 mRNA CTD PMID:16886892 NCBI chr 3:97,640,923...97,667,617 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] CTD PMID:32544411 NCBI chr 4:104,363,838...104,425,271 JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 increases expression ISO lycopene results in increased expression of EIF4G1 mRNA CTD PMID:16886892 NCBI chr11:93,726,322...93,746,387 JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] CTD PMID:32544411 NCBI chr10:91,826,663...91,920,976 JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
lycopene results in increased expression of ESR1 mRNA
CTD PMID:16886892 PMID:17051425 NCBI chr 1:43,511,685...43,904,454 JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:100,589,553...100,645,240 JBrowse link
G Fancc FA complementation group C decreases expression ISO lycopene results in decreased expression of FANCC mRNA CTD PMID:16886892 NCBI chr17:1,686,374...1,818,672 JBrowse link
G Fancf FA complementation group F decreases expression ISO lycopene results in decreased expression of FANCF mRNA CTD PMID:16886892 NCBI chr 1:110,585,054...110,587,870 JBrowse link
G Faslg Fas ligand decreases expression ISO lycopene results in decreased expression of FASLG mRNA CTD PMID:16886892 NCBI chr13:76,680,885...76,706,042 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO lycopene results in increased expression of FOS mRNA CTD PMID:16886892 NCBI chr 6:110,852,188...110,855,054 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GCLC mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLC mRNA] CTD PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr 8:87,510,251...87,548,896 JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Lycopene results in increased expression of GCLM protein
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA]
CTD PMID:35917956 PMID:36216167 NCBI chr 2:213,032,135...213,052,192 JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 decreases expression ISO Lycopene results in decreased expression of GET1 mRNA CTD PMID:16886892 NCBI chr11:48,915,298...48,929,235 JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO
EXP
lycopene results in decreased expression of GFAP mRNA
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein]
CTD PMID:19555370 PMID:32544411 NCBI chr10:88,352,987...88,361,661 JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO
EXP
lycopene results in increased expression of GJA1 protein
Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein]
CTD PMID:16091010 PMID:31568845 NCBI chr20:36,302,490...36,315,010 JBrowse link
G Gja4 gap junction protein, alpha 4 decreases expression ISO lycopene results in decreased expression of GJA4 mRNA CTD PMID:16886892 NCBI chr 5:144,917,791...144,920,324 JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression
increases expression
ISO lycopene results in decreased expression of GJA5 mRNA
lycopene results in increased expression of GJA5 mRNA
CTD PMID:16886892 NCBI chr 2:187,291,227...187,310,770 JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX1 mRNA]
Lycopene results in increased expression of GPX1 mRNA
[Glucose co-treated with Lycopene] results in increased expression of GPX1 mRNA
CTD PMID:36216167 PMID:38444079 NCBI chr 8:117,905,462...117,906,588 JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GPX2 mRNA] CTD PMID:36216167 NCBI chr 6:101,226,745...101,230,033 JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX3 mRNA
Lycopene affects the reaction [Atrazine affects the expression of GPX3 mRNA]
CTD PMID:36216167 NCBI chr10:39,529,335...39,537,406 JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
multiple interactions
ISO lycopene results in decreased expression of GPX4 mRNA
Lycopene affects the reaction [Atrazine affects the expression of GPX4 mRNA]
CTD PMID:16886892 PMID:36216167 NCBI chr 7:10,300,833...10,303,629 JBrowse link
G Gpx5 glutathione peroxidase 5 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of GPX5 mRNA] CTD PMID:36216167 NCBI chr17:48,131,853...48,138,801 JBrowse link
G Gpx6 glutathione peroxidase 6 increases expression ISO Lycopene results in increased expression of GPX6 mRNA CTD PMID:36216167 NCBI chr17:48,104,197...48,111,816 JBrowse link
G Gpx7 glutathione peroxidase 7 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX7 mRNA
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX7 mRNA]
CTD PMID:36216167 NCBI chr 5:128,373,881...128,381,866 JBrowse link
G Gpx8 glutathione peroxidase 8 increases expression
multiple interactions
ISO Lycopene results in increased expression of GPX8 mRNA
Lycopene inhibits the reaction [Atrazine results in decreased expression of GPX8 mRNA]
CTD PMID:36216167 NCBI chr 2:46,409,646...46,413,401 JBrowse link
G Gsdmd gasdermin D multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSDMD protein] CTD PMID:36610486 NCBI chr 7:109,423,209...109,427,771 JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] CTD PMID:25682699 NCBI chr16:65,185,574...65,228,742 JBrowse link
G Gss glutathione synthetase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] CTD PMID:35917956 PMID:36610486 NCBI chr 3:164,508,005...164,538,343 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
EXP [Glucose co-treated with Lycopene] results in increased expression of GSTP1 mRNA
Lycopene results in increased expression of GSTP1 mRNA
CTD PMID:38444079 NCBI chr 1:210,767,237...210,770,242 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
decreases response to substance
ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein]
lycopene results in decreased susceptibility to HMGB1 protein
CTD PMID:22429818 NCBI chr12:11,009,236...11,015,941 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA]
[lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein
lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA]
CTD PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 PMID:35917956 More... NCBI chr19:13,452,365...13,479,823 JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] CTD PMID:19071209 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions EXP lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] CTD PMID:23076637 NCBI chr10:37,908,866...37,951,994 JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] CTD PMID:32544411 NCBI chr 3:38,453,016...38,457,475 JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:22429818 PMID:25551565 NCBI chr 8:27,829,688...27,841,618 JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
ISO
EXP
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein]
lycopene results in decreased expression of IGF1 mRNA
lycopene results in increased expression of IGF1 mRNA
CTD PMID:15084515 PMID:16565789 PMID:16886892 NCBI chr 7:24,169,608...24,249,446 JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO lycopene results in decreased expression of IGF1R protein CTD PMID:17337101 NCBI chr 1:130,959,787...131,248,664 JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO lycopene results in increased expression of IGFBP2 protein CTD PMID:17337101 NCBI chr 9:81,864,811...81,892,179 JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
Lycopene inhibits the reaction [Atrazine results in decreased expression of IL10 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL10 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL10]
CTD PMID:25551565 PMID:25682699 PMID:36216167 PMID:36583613 NCBI chr13:45,024,921...45,029,586 JBrowse link
G Il18 interleukin 18 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 NCBI chr 8:59,802,072...59,829,275 JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B] CTD PMID:25682699 PMID:28974442 PMID:36216167 PMID:36610486 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Il2 interleukin 2 multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] CTD PMID:25682699 NCBI chr 2:121,932,968...121,937,672 JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP
ISO
lycopene results in decreased expression of IL6 mRNA
Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6]
CTD PMID:15084515 PMID:25682699 PMID:36216167 PMID:36583613 NCBI chr 4:5,889,999...5,894,575 JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of IRF3 protein] CTD PMID:36583613 NCBI chr 1:104,616,608...104,621,402 JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF7 mRNA] CTD PMID:36583613 NCBI chr 1:205,796,956...205,800,543 JBrowse link
G Ivl involucrin decreases expression ISO lycopene results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 2:180,842,307...180,854,646 JBrowse link
G Jak1 Janus kinase 1 increases expression ISO lycopene results in increased expression of JAK1 mRNA CTD PMID:16886892 NCBI chr 5:120,895,606...121,004,207 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO lycopene results in decreased expression of JUN mRNA CTD PMID:16886892 NCBI chr 5:115,009,900...115,012,993 JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of KEAP1 protein]
Lycopene results in increased expression of KEAP1 mRNA
CTD PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr 8:28,044,555...28,054,042 JBrowse link
G Kif2a kinesin family member 2A increases expression ISO lycopene results in increased expression of KIF2A mRNA CTD PMID:16886892 NCBI chr 2:40,101,548...40,164,780 JBrowse link
G Kpna2 karyopherin subunit alpha 2 increases expression ISO lycopene results in increased expression of KPNA2 mRNA CTD PMID:16886892 NCBI chr10:92,433,678...92,445,841 JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO lycopene results in increased expression of LDLR mRNA CTD PMID:16886892 NCBI chr 8:28,546,191...28,569,075 JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO lycopene results in increased expression of LIPA mRNA CTD PMID:16886892 NCBI chr 1:241,437,524...241,470,936 JBrowse link
G Lpo lactoperoxidase multiple interactions ISO lycopene inhibits the reaction [Diethylnitrosamine results in increased expression of LPO protein] CTD PMID:24144777 NCBI chr10:73,104,170...73,124,683 JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO
EXP
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased localization of MAP1LC3B protein]
[Glucose co-treated with Lycopene] results in increased expression of MAP1LC3B mRNA
CTD PMID:36583613 PMID:38444079 NCBI chr19:66,571,631...66,582,270 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO lycopene results in increased expression of MAP2K1 mRNA CTD PMID:16886892 NCBI chr 8:73,578,747...73,650,184 JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO lycopene results in decreased expression of MAP2K2 protein CTD PMID:17337101 NCBI chr 7:9,241,449...9,264,216 JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 decreases expression ISO lycopene results in decreased expression of MAP2K4 protein CTD PMID:17337101 NCBI chr10:50,842,348...50,947,063 JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO lycopene results in decreased expression of MAP2K6 protein CTD PMID:17337101 NCBI chr10:95,872,747...95,987,747 JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
EXP
ISO
Lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK1 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of MAPK1 protein]
Lycopene results in increased expression of MAPK1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of MAPK1 mRNA]
CTD PMID:19551842 PMID:30360616 PMID:32153214 NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression
multiple interactions
increases expression
ISO
EXP
lycopene results in decreased expression of MAPK14 protein
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of MAPK14 protein]
lycopene results in increased expression of MAPK14 mRNA
CTD PMID:16886892 PMID:17337101 PMID:32544411 NCBI chr20:6,751,288...6,812,294 JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression ISO lycopene results in decreased expression of MAPK3 protein CTD PMID:17337101 NCBI chr 1:190,797,189...190,803,411 JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases expression ISO lycopene results in decreased expression of MAPK8 protein CTD PMID:17337101 NCBI chr16:8,645,171...8,728,225 JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression ISO lycopene results in increased expression of MGAT2 mRNA CTD PMID:16886892 NCBI chr 6:93,392,416...93,394,905 JBrowse link
G Mill1 MHC I like leukocyte 1 increases expression ISO Lycopene results in increased expression of MICA mRNA CTD PMID:16886892 NCBI chr 1:87,500,591...87,526,983 JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of MKI67 protein] CTD PMID:33592256 NCBI chr 1:199,926,150...199,952,847 JBrowse link
G Mlh1 mutL homolog 1 increases expression ISO lycopene results in increased expression of MLH1 mRNA CTD PMID:16886892 NCBI chr 8:120,074,871...120,112,109 JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO lycopene inhibits the reaction [Acetaminophen results in increased activity of MMP2 protein] CTD PMID:27989599 NCBI chr19:30,327,643...30,355,856 JBrowse link
G Msh2 mutS homolog 2 increases expression ISO lycopene results in increased expression of MSH2 mRNA CTD PMID:16886892 NCBI chr 6:12,567,368...12,626,534 JBrowse link
G Msh6 mutS homolog 6 increases expression ISO lycopene results in increased expression of MSH6 mRNA CTD PMID:16886892 NCBI chr 6:12,316,190...12,333,505 JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP
ISO
lycopene results in increased expression of NFE2L2 mRNA; lycopene results in increased expression of NFE2L2 protein
Lycopene inhibits the reaction [Atrazine affects the localization of NFE2L2 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein]
lycopene promotes the reaction [Atrazine results in increased expression of NFE2L2 mRNA]
CTD PMID:19551842 PMID:27102619 PMID:30360616 PMID:35917956 PMID:36216167 More... NCBI chr 3:81,001,529...81,031,165 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP lycopene inhibits the reaction [Atrazine results in increased expression of NFKB1 mRNA] CTD PMID:27102619 NCBI chr 2:226,689,745...226,805,897 JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] CTD PMID:25551565 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] CTD PMID:36610486 NCBI chr10:44,826,299...44,853,373 JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression ISO lycopene results in decreased expression of NOS1 mRNA CTD PMID:16886892 NCBI chr12:44,276,011...44,456,371 JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] CTD PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr19:52,205,374...52,220,267 JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Lycopene increases expression of NR1H3 protein in macrophages RGD PMID:21208793 RGD:401842374 NCBI chr 3:97,614,616...97,632,053 JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein]
Lycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 protein
CTD PMID:36216167 PMID:36403809 NCBI chr11:75,965,717...76,006,733 JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 protein]
Lycopene results in increased expression of NR1I3 mRNA
CTD PMID:36216167 PMID:36403809 NCBI chr13:86,165,327...86,170,362 JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions ISO [Lycopene co-treated with Atrazine] results in increased expression of NR3C2 mRNA CTD PMID:36216167 NCBI chr19:47,619,853...47,964,089 JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression
multiple interactions
EXP Lycopene results in increased expression of NTRK2 protein
Lycopene inhibits the reaction [bisphenol A results in decreased expression of NTRK2 protein]
CTD PMID:32153214 NCBI chr17:5,560,558...5,875,899 JBrowse link
G Nup214 nucleoporin 214 decreases expression ISO lycopene results in decreased expression of NUP214 mRNA CTD PMID:16886892 NCBI chr 3:35,652,841...35,738,323 JBrowse link
G Nup62 nucleoporin 62 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NUP62 mRNA] CTD PMID:35917956 NCBI chr 1:104,435,532...104,451,392 JBrowse link
G P22k15 cystatin related protein 2 decreases expression EXP lycopene results in decreased expression of P22K15 mRNA CTD PMID:15084515 NCBI chr 3:157,420,930...157,427,988 JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO lycopene results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:23,793,096...23,885,631 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] CTD PMID:23076637 NCBI chr13:94,839,484...94,871,295 JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP lycopene inhibits the reaction [[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PCNA protein] CTD PMID:19551842 NCBI chr 3:139,951,948...139,955,820 JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 protein] CTD PMID:36583613 NCBI chr 5:155,813,838...155,825,950 JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein] CTD PMID:22429818 NCBI chr 5:156,359,725...156,362,302 JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP lycopene inhibits the reaction [Atrazine results in increased secretion of POMC protein modified form] CTD PMID:27102619 NCBI chr 6:32,659,137...32,665,175 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of PPARA mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of PPARA protein] CTD PMID:36216167 NCBI chr 7:118,712,261...118,780,723 JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
ISO Lycopene results in increased expression of PPARG mRNA
[Lycopene co-treated with Atrazine] results in increased expression of PPARG mRNA
CTD PMID:36216167 NCBI chr 4:150,095,743...150,221,104 JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX1 mRNA] CTD PMID:36216167 NCBI chr 5:135,383,906...135,399,504 JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX2 mRNA] CTD PMID:36216167 NCBI chr19:40,085,788...40,091,083 JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases expression
increases phosphorylation
ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAA2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased phosphorylation of PRKAA2 protein]
Lycopene results in increased expression of PRKAA2 mRNA
Lycopene results in increased phosphorylation of PRKAA2 protein
CTD PMID:30360616 NCBI chr 5:125,036,945...125,109,010 JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAB1 mRNA] CTD PMID:30360616 NCBI chr12:46,248,971...46,259,487 JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of PRKAB2 mRNA] CTD PMID:30360616 NCBI chr 2:187,946,008...187,961,615 JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 multiple interactions ISO Lycopene affects the reaction [Atrazine results in increased expression of PRKAG2 mRNA] CTD PMID:30360616 NCBI chr 4:10,744,695...10,985,939 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression ISO lycopene results in decreased expression of PRKDC mRNA CTD PMID:16886892 NCBI chr11:98,544,952...98,762,499 JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] CTD PMID:36583613 NCBI chr 1:51,236,410...52,430,242 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of PTGS2 mRNA]; Lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA] CTD PMID:28974442 PMID:36216167 NCBI chr13:64,714,063...64,722,320 JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD protein] CTD PMID:36610486 NCBI chr 1:192,032,124...192,033,419 JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression ISO lycopene results in increased expression of RAD50 mRNA CTD PMID:16886892 NCBI chr10:38,310,147...38,362,100 JBrowse link
G Rassf7 Ras association domain family member 7 increases expression ISO lycopene results in increased expression of RASSF7 mRNA CTD PMID:16886892 NCBI chr 1:205,749,173...205,753,350 JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein]
lycopene results in decreased phosphorylation of RB1 protein
CTD PMID:16565789 PMID:17051425 PMID:17337101 NCBI chr15:54,780,858...54,911,989 JBrowse link
G Rdx radixin decreases expression ISO lycopene results in decreased expression of RDX mRNA CTD PMID:16886892 NCBI chr 8:61,275,792...61,348,260 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein] CTD PMID:36583613 NCBI chr 1:212,354,336...212,364,815 JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions EXP [Glucose co-treated with Lycopene] results in increased expression of RIPK1 mRNA CTD PMID:38444079 NCBI chr17:31,044,983...31,077,167 JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions EXP [Glucose co-treated with Lycopene] results in increased expression of RIPK3 mRNA CTD PMID:38444079 NCBI chr15:33,253,071...33,262,025 JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 decreases expression ISO lycopene results in decreased expression of RPS6KA1 protein CTD PMID:17337101 NCBI chr 5:151,362,819...151,402,064 JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 decreases expression ISO lycopene results in decreased expression of RPS6KA3 protein CTD PMID:17337101 NCBI chr  X:39,325,926...39,432,017 JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO lycopene results in increased expression of RRM2 mRNA CTD PMID:16886892 NCBI chr 6:47,044,755...47,075,370 JBrowse link
G Sbp spermine binding protein decreases expression EXP lycopene results in decreased expression of SBP mRNA CTD PMID:15084515 NCBI chr10:13,450,613...13,473,016 JBrowse link
G Scgb1d2 secretoglobin, family 1D, member 2 decreases expression EXP lycopene results in decreased expression of SCGB1D2 mRNA CTD PMID:15084515 NCBI chr 1:215,653,464...215,658,101 JBrowse link
G Scgb1d4 secretoglobin family 1D member 4 decreases expression EXP lycopene results in decreased expression of SCGB1D4 mRNA CTD PMID:15084515 NCBI chr 1:215,755,363...215,758,238 JBrowse link
G Sele selectin E multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:22429818 PMID:25551565 NCBI chr13:78,935,997...78,945,905 JBrowse link
G Selenop selenoprotein P decreases expression ISO lycopene results in decreased expression of SELENOP mRNA CTD PMID:16886892 NCBI chr 2:54,225,736...54,236,022 JBrowse link
G Selenos selenoprotein S increases expression EXP Lycopene results in increased expression of SELENOS mRNA CTD PMID:38444079 NCBI chr 1:129,070,240...129,080,007 JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO lycopene inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein] CTD PMID:28974442 NCBI chr20:25,305,953...25,328,000 JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO lycopene results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:82,281,221...82,431,664 JBrowse link
G Smad3 SMAD family member 3 increases expression ISO lycopene results in increased expression of SMAD3 mRNA CTD PMID:16886892 NCBI chr 8:73,022,204...73,132,324 JBrowse link
G Smc1a structural maintenance of chromosomes 1A decreases expression ISO lycopene results in decreased expression of SMC1A mRNA CTD PMID:16886892 NCBI chr  X:24,582,732...24,627,462 JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 mRNA]; Lycopene promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein]
[Glucose co-treated with Lycopene] results in increased expression of SOD1 mRNA
Lycopene results in increased expression of SOD1 mRNA
CTD PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 NCBI chr11:42,942,742...42,948,399 JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 protein]
Lycopene results in increased expression of SOD2 mRNA
[Glucose co-treated with Lycopene] results in increased expression of SOD2 mRNA
CTD PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 NCBI chr 1:50,043,323...50,050,168 JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of SOD3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD3 mRNA] CTD PMID:35917956 PMID:36216167 PMID:36610486 NCBI chr14:62,822,865...62,828,602 JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO
EXP
Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein]
[Glucose co-treated with Lycopene] results in increased expression of SQSTM1 mRNA
CTD PMID:30360616 PMID:36583613 PMID:38444079 NCBI chr10:35,026,598...35,037,750 JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP lycopene results in decreased expression of SRD5A1 mRNA CTD PMID:15084515 NCBI chr 1:35,514,914...35,548,898 JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of STAR protein]; lycopene inhibits the reaction [decamethrin results in decreased expression of STAR mRNA] CTD PMID:19071209 PMID:23076637 NCBI chr16:72,969,824...72,974,447 JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression ISO lycopene results in increased expression of STAT3 mRNA CTD PMID:16886892 NCBI chr10:86,311,528...86,363,513 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 protein] CTD PMID:36583613 NCBI chr18:27,606,196...27,612,544 JBrowse link
G Tbk1 TANK-binding kinase 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of TBK1 protein] CTD PMID:36583613 NCBI chr 7:58,963,319...58,996,357 JBrowse link
G Tff1 trefoil factor 1 decreases expression ISO lycopene results in decreased expression of TFF1 mRNA CTD PMID:16886892 NCBI chr20:9,237,095...9,240,956 JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 decreases expression ISO lycopene results in decreased expression of TFPI2 mRNA CTD PMID:16886892 NCBI chr 4:32,936,462...32,941,385 JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO lycopene results in increased expression of TGFA mRNA CTD PMID:16886892 NCBI chr 4:120,175,549...120,258,342 JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] CTD PMID:22429818 NCBI chr 2:171,499,189...171,504,831 JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
Lycopene affects the reaction [Atrazine affects the expression of TLR4 mRNA]
CTD PMID:22429818 PMID:36216167 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
[Lycopene co-treated with Diethylnitrosamine] results in increased expression of TNF mRNA; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of TNF protein]
Lycopene inhibits the reaction [Atrazine results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TNF protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF]
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
CTD PMID:19551842 PMID:22429818 PMID:25551565 PMID:25682699 PMID:28974442 More... NCBI chr20:3,626,685...3,629,303 JBrowse link
G Tp53 tumor protein p53 decreases expression
multiple interactions
ISO lycopene results in decreased expression of TP53 mRNA
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA]
CTD PMID:16886892 PMID:36583613 NCBI chr10:54,798,871...54,810,300 JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 protein] CTD PMID:36216167 NCBI chr 3:108,418,537...108,443,330 JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TSHB protein] CTD PMID:33592256 NCBI chr 2:192,913,171...192,918,054 JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO Lycopene affects the reaction [Atrazine affects the expression of TXN1 mRNA] CTD PMID:36216167 NCBI chr 5:77,507,455...77,519,685 JBrowse link
G Txn2 thioredoxin 2 multiple interactions
decreases expression
ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of TXN2 mRNA]
Lycopene results in decreased expression of TXN2 mRNA
CTD PMID:36216167 NCBI chr 7:111,377,338...111,390,940 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein] CTD PMID:22429818 NCBI chr 2:206,723,050...206,742,783 JBrowse link
G Vcp valosin-containing protein increases expression ISO lycopene results in increased expression of VCP mRNA CTD PMID:16886892 NCBI chr 5:62,005,984...62,025,387 JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of VEGFA protein] CTD PMID:33592256 NCBI chr 9:22,452,854...22,468,194 JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein] CTD PMID:36583613 NCBI chr14:84,604,623...84,609,707 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        nonmetal atom 19818
          carbon atom 19770
            organic molecular entity 19770
              isoprenoid 14082
                terpene 14082
                  tetraterpene 601
                    carotene 601
                      acyclic carotene 251
                        13-cis-lycopene 0
                        15-cis-lycopene 0
                        4,4'-diapolycopene + 0
                        5-cis-lycopene 0
                        7,7',9,9'-tetra-cis-lycopene 0
                        7,9,9'-tri-cis-neurosporene 0
                        9-cis-lycopene 0
                        all-trans-3,4-didehydrolycopene 0
                        lycopaoctaene 0
                        lycopene + 251
                        neurosporene + 0
                        phytoene + 2
                        phytofluene + 2
                        zeta-carotene + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    main group molecular entity 19835
                      s-block molecular entity 19670
                        hydrogen molecular entity 19652
                          hydrides 19164
                            organic hydride 18711
                              organic fundamental parent 18711
                                hydrocarbon 18462
                                  terpene 14082
                                    tetraterpene 601
                                      carotene 601
                                        acyclic carotene 251
                                          13-cis-lycopene 0
                                          15-cis-lycopene 0
                                          4,4'-diapolycopene + 0
                                          5-cis-lycopene 0
                                          7,7',9,9'-tetra-cis-lycopene 0
                                          7,9,9'-tri-cis-neurosporene 0
                                          9-cis-lycopene 0
                                          all-trans-3,4-didehydrolycopene 0
                                          lycopaoctaene 0
                                          lycopene + 251
                                          neurosporene + 0
                                          phytoene + 2
                                          phytofluene + 2
                                          zeta-carotene + 0
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