|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] |
CTD |
PMID:17051425 |
|
NCBI chr 1:43,511,685...43,904,454
|
|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr 6:100,589,553...100,645,240
|
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] |
CTD |
PMID:17051425 |
|
NCBI chr 1:43,511,685...43,904,454
|
|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr 6:100,589,553...100,645,240
|
|
|
G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
EXP |
Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein] |
CTD |
PMID:32153214 |
|
NCBI chr10:91,410,129...91,430,246
|
|
G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] |
CTD |
PMID:22192907 PMID:26900785 |
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Acvr2b |
activin A receptor type 2B |
decreases expression |
EXP |
Lycopene results in decreased expression of SCGB2A2 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 8:128,016,589...128,056,193
|
|
G |
Add1 |
adducin 1 |
decreases expression |
ISO |
lycopene results in decreased expression of ADD1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr14:80,333,242...80,401,641
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] |
CTD |
PMID:22429818 |
|
NCBI chr20:4,152,758...4,155,956
|
|
G |
Ahr |
aryl hydrocarbon receptor |
decreases expression multiple interactions |
ISO |
lycopene results in decreased expression of AHR mRNA [Lycopene co-treated with Atrazine] results in increased expression of AHR mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of AHR protein] |
CTD |
PMID:16886892 PMID:36216167 PMID:36403809 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] |
CTD |
PMID:28974442 |
|
NCBI chr20:3,651,435...3,657,341
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
lycopene results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:17337101 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Alad |
aminolevulinate dehydratase |
multiple interactions |
ISO EXP |
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein] lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein] |
CTD |
PMID:17516994 PMID:25682699 |
|
NCBI chr 5:80,977,562...80,987,901
|
|
G |
Andpro |
androgen regulated protein |
decreases expression |
EXP |
lycopene results in decreased expression of ANDPRO mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 3:157,171,739...157,178,262
|
|
G |
Aqp1 |
aquaporin 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of AQP1 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 4:85,812,784...85,824,964
|
|
G |
Aqp11 |
aquaporin 11 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP11 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 1:161,457,752...161,467,918
|
|
G |
Aqp2 |
aquaporin 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 protein] |
CTD |
PMID:33960999 |
|
NCBI chr 7:132,590,286...132,595,321
|
|
G |
Aqp4 |
aquaporin 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP4 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr18:6,782,389...6,799,034
|
|
G |
Aqp6 |
aquaporin 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP6 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 7:132,611,069...132,614,004
|
|
G |
Aqp7 |
aquaporin 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP7 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 5:60,968,495...60,982,618
|
|
G |
Ar |
androgen receptor |
decreases expression |
ISO |
lycopene results in decreased expression of AR mRNA |
CTD |
PMID:16886892 |
|
NCBI chr X:67,135,317...67,304,476
|
|
G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of ARNT mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT protein] |
CTD |
PMID:36216167 PMID:36403809 |
|
NCBI chr 2:185,686,703...185,745,546
|
|
G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr13:85,460,312...85,639,959
|
|
G |
Atg10 |
autophagy related 10 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:23,843,695...24,133,459
|
|
G |
Atg13 |
autophagy related 13 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 3:98,102,831...98,136,741
|
|
G |
Atg14 |
autophagy related 14 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr15:23,275,457...23,306,817
|
|
G |
Atg16l1 |
autophagy related 16-like 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 9:95,869,839...95,905,354
|
|
G |
Atg16l2 |
autophagy related 16-like 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 1:165,100,946...165,123,307
|
|
G |
Atg2b |
autophagy related 2B |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 6:130,286,979...130,357,109
|
|
G |
Atg3 |
autophagy related 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr11:69,130,948...69,159,280
|
|
G |
Atg4a |
autophagy related 4A, cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr X:109,453,712...109,553,758
|
|
G |
Atg4b |
autophagy related 4B, cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 9:101,729,772...101,761,456
|
|
G |
Atg4c |
autophagy related 4C, cysteine peptidase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 5:118,977,594...119,050,894
|
|
G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA] [Glucose co-treated with Lycopene] results in increased expression of ATG5 mRNA |
CTD |
PMID:30360616 PMID:38444079 |
|
NCBI chr20:49,380,835...49,471,826
|
|
G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 4:149,390,000...149,597,534
|
|
G |
Atg9a |
autophagy related 9A |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 9:84,126,071...84,136,723
|
|
G |
Atg9b |
autophagy related 9B |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 4:11,678,548...11,686,097
|
|
G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 2:191,709,311...191,737,414
|
|
G |
Atp1a2 |
ATPase Na+/K+ transporting subunit alpha 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr13:87,261,964...87,286,911
|
|
G |
Atp1a3 |
ATPase Na+/K+ transporting subunit alpha 3 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr 1:89,700,645...89,729,782
|
|
G |
Atp1a4 |
ATPase Na+/K+ transporting subunit alpha 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr13:87,216,139...87,252,155
|
|
G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr13:79,319,708...79,340,226
|
|
G |
Atp1b2 |
ATPase Na+/K+ transporting subunit beta 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr10:54,817,473...54,823,708
|
|
G |
Atp1b3 |
ATPase Na+/K+ transporting subunit beta 3 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr 8:105,789,824...105,821,151
|
|
G |
Atp1b4 |
ATPase Na+/K+ transporting family member beta 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] |
CTD |
PMID:26476475 PMID:33960999 |
|
NCBI chr X:121,952,923...121,974,146
|
|
G |
Atp2a1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] |
CTD |
PMID:27112537 |
|
NCBI chr 1:190,457,198...190,475,410
|
|
G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr12:39,733,519...39,782,942
|
|
G |
Atp2a3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr10:58,079,710...58,111,279
|
|
G |
Atp2b1 |
ATPase plasma membrane Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2B1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 7:35,622,267...35,731,904
|
|
G |
Atp2b2 |
ATPase plasma membrane Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 4:148,450,207...148,763,653
|
|
G |
Atp2b3 |
ATPase plasma membrane Ca2+ transporting 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr X:156,367,582...156,464,085
|
|
G |
Atp2b4 |
ATPase plasma membrane Ca2+ transporting 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr13:47,708,157...47,807,389
|
|
G |
Atp2c1 |
ATPase secretory pathway Ca2+ transporting 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2C1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 8:114,913,551...115,034,706
|
|
G |
Atp2c2 |
ATPase secretory pathway Ca2+ transporting 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr19:64,662,729...64,719,998
|
|
G |
Bach1 |
BTB domain and CNC homolog 1 |
increases expression |
ISO |
lycopene results in increased expression of BACH1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:40,425,721...40,461,118
|
|
G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAK1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr20:5,102,334...5,111,615
|
|
G |
Bap1 |
BRCA1 associated deubiquitinase 1 |
increases expression |
ISO |
lycopene results in increased expression of BAP1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr16:6,453,126...6,461,952
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA] Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA] |
CTD |
PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:36583613 |
|
NCBI chr 1:105,076,472...105,081,906
|
|
G |
Bche |
butyrylcholinesterase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] |
CTD |
PMID:26900785 |
|
NCBI chr 2:160,607,289...160,699,760
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
[Glucose co-treated with Lycopene] results in increased expression of BCL2 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA] lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA] Lycopene results in increased expression of BCL2 mRNA |
CTD |
PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:38444079 More...
|
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
Bco1 |
beta-carotene oxygenase 1 |
multiple interactions |
ISO |
BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] |
CTD |
PMID:21935922 |
|
NCBI chr19:62,058,061...62,094,923
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein] Lycopene inhibits the reaction [bisphenol A results in decreased expression of BDNF protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein] |
CTD |
PMID:28974442 PMID:32153214 PMID:32544411 |
|
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Becn1 |
beclin 1 |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA] [Glucose co-treated with Lycopene] results in increased expression of BECN1 mRNA |
CTD |
PMID:30360616 PMID:38444079 |
|
NCBI chr10:86,731,649...86,747,002
|
|
G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
decreases expression |
ISO |
lycopene results in decreased expression of BRAF protein |
CTD |
PMID:17337101 |
|
NCBI chr 4:69,329,772...69,476,931
|
|
G |
C1qa |
complement C1q A chain |
decreases expression |
ISO |
lycopene results in decreased expression of C1QA mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 5:154,417,086...154,419,933
|
|
G |
C4b |
complement C4B |
decreases expression |
ISO |
lycopene results in decreased expression of C4B mRNA |
CTD |
PMID:19555370 |
|
NCBI chr20:4,201,979...4,216,292
|
|
G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] |
CTD |
PMID:33592256 |
|
NCBI chr 1:178,312,636...178,317,588
|
|
G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP1 protein] |
CTD |
PMID:36610486 |
|
NCBI chr 8:10,746,338...10,882,295
|
|
G |
Casp3 |
caspase 3 |
multiple interactions |
EXP ISO |
[Glucose co-treated with Lycopene] results in increased expression of CASP3 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] |
CTD |
PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32153214 PMID:32544411 PMID:36583613 PMID:38444079 More...
|
|
NCBI chr16:52,395,539...52,413,794
|
|
G |
Casp8 |
caspase 8 |
multiple interactions decreases expression |
EXP ISO |
[Glucose co-treated with Lycopene] results in increased expression of CASP8 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] lycopene results in decreased expression of CASP8 mRNA |
CTD |
PMID:16030430 PMID:16886892 PMID:38444079 |
|
NCBI chr 9:67,747,109...67,806,699
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G |
Casp9 |
caspase 9 |
multiple interactions |
EXP ISO |
[Glucose co-treated with Lycopene] results in increased expression of CASP9 mRNA; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] |
CTD |
PMID:27871895 PMID:38444079 |
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|
|
G |
Cat |
catalase |
multiple interactions increases expression increases activity decreases expression |
EXP ISO |
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA] lycopene results in increased expression of CAT lycopene results in increased activity of CAT protein Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein] Lycopene results in decreased expression of CAT mRNA |
CTD |
PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 PMID:26900785 PMID:27102619 PMID:27989599 PMID:30360616 PMID:31568845 PMID:32544411 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr 3:110,297,340...110,329,526
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL4 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr10:68,963,893...68,965,728
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL5 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr10:68,820,330...68,824,906
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|
G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression |
ISO EXP |
lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein] lycopene results in decreased expression of CCND1 protein lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein] |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 |
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NCBI chr 1:209,518,288...209,527,986
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G |
Ccne1 |
cyclin E1 |
decreases expression increases expression |
ISO |
lycopene results in decreased expression of CCNE1 protein lycopene results in increased expression of CCNE1 mRNA |
CTD |
PMID:16886892 PMID:17337101 |
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NCBI chr 1:99,918,672...99,927,986
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G |
Ccs |
copper chaperone for superoxide dismutase |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of CCS mRNA [Glucose co-treated with Lycopene] results in increased expression of CCS mRNA |
CTD |
PMID:38444079 |
|
NCBI chr 1:211,543,192...211,564,354
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|
G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK1 protein |
CTD |
PMID:17337101 |
|
NCBI chr20:19,265,252...19,280,456
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|
G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK4 protein |
CTD |
PMID:17337101 |
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NCBI chr 7:64,771,453...64,774,891
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G |
Cdk5 |
cyclin-dependent kinase 5 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK5 protein |
CTD |
PMID:17337101 |
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NCBI chr 4:11,647,098...11,651,606
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G |
Cdk7 |
cyclin-dependent kinase 7 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK7 protein |
CTD |
PMID:17337101 |
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NCBI chr 2:33,574,623...33,599,485
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|
G |
Cdk9 |
cyclin-dependent kinase 9 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK9 protein |
CTD |
PMID:17337101 |
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NCBI chr 3:36,394,168...36,399,016
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] |
CTD |
PMID:16565789 |
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NCBI chr20:7,150,820...7,161,373
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G |
Cgas |
cyclic GMP-AMP synthase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS protein] |
CTD |
PMID:36583613 |
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NCBI chr 8:88,172,559...88,187,538
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G |
Chga |
chromogranin A |
increases expression |
ISO |
lycopene results in increased expression of CHGA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:127,460,895...127,472,238
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G |
Chgb |
chromogranin B |
decreases expression |
ISO |
lycopene results in decreased expression of CHGB mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 3:140,496,712...140,510,057
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] |
CTD |
PMID:26900785 |
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NCBI chr 6:136,550,583...136,553,464
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G |
Crb1 |
crumbs cell polarity complex component 1 |
decreases expression |
ISO |
lycopene results in decreased expression of CRB1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr13:53,352,932...53,540,019
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [bisphenol A results in decreased expression of CREB1 protein] Lycopene results in increased expression of CREB1 protein |
CTD |
PMID:32153214 |
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NCBI chr 9:73,397,333...73,466,339
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CSF2 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr10:38,887,692...38,889,673
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|
G |
Ctss |
cathepsin S |
decreases expression |
ISO |
lycopene results in decreased expression of CTSS mRNA |
CTD |
PMID:19555370 |
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NCBI chr 2:185,775,316...185,803,440
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 protein] |
CTD |
PMID:36583613 |
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NCBI chr14:15,989,066...15,991,263
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
ISO |
lycopene results in decreased expression of CXCL14 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr17:8,323,150...8,331,176
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|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL2 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr14:17,465,210...17,467,255
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|
G |
Cyb5a |
cytochrome b5 type A |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] |
CTD |
PMID:26775023 |
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NCBI chr18:80,487,923...80,520,544
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G |
Cygb |
cytoglobin |
increases expression |
EXP |
Lycopene results in increased expression of CYGB mRNA |
CTD |
PMID:38444079 |
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NCBI chr10:102,376,506...102,386,272
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] |
CTD |
PMID:19071209 |
|
NCBI chr 8:67,318,665...67,330,196
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity multiple interactions |
ISO |
lycopene results in decreased activity of CYP1A1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 protein] |
CTD |
PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr 8:66,991,940...66,998,014
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases expression |
ISO |
[Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 protein] Lycopene results in increased expression of CYP1A2 mRNA |
CTD |
PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr 8:66,971,261...66,978,149
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity multiple interactions increases expression |
ISO |
lycopene results in decreased activity of CYP1B1 protein [Lycopene co-treated with Atrazine] results in increased expression of CYP1B1 mRNA; Lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 protein] Lycopene results in increased expression of CYP1B1 mRNA |
CTD |
PMID:19329757 PMID:26775023 PMID:36216167 PMID:36403809 |
|
NCBI chr 6:21,093,927...21,103,091
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G |
Cyp2a3 |
cytochrome P450, family 2, subfamily a, polypeptide 3 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of CYP2A4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2A4 mRNA] |
CTD |
PMID:26775023 PMID:36216167 |
|
NCBI chr 1:91,299,584...91,307,650
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|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
Lycopene promotes the reaction [Atrazine results in increased expression of CYP2B10 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 1:90,780,468...90,859,852
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|
G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine results in increased expression of CYP2C29 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 1:247,879,058...247,916,804
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|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 protein] |
CTD |
PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr 1:205,269,967...205,280,365
|
|
G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2F2 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 1:91,543,768...91,557,553
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|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases activity |
ISO |
Lycopene results in increased activity of CYP3A4 protein |
CTD |
PMID:16632523 |
|
NCBI chr12:14,321,771...14,343,886
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|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr12:21,919,955...21,960,160
|
|
G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4V3 mRNA] Lycopene results in increased expression of CYP4V3 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr16:53,650,978...53,675,916
|
|
G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] |
CTD |
PMID:26775023 |
|
NCBI chr 2:102,419,011...102,586,047
|
|
G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
lycopene results in increased expression of DDB2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 3:97,640,923...97,667,617
|
|
G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 4:104,363,838...104,425,271
|
|
G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
increases expression |
ISO |
lycopene results in increased expression of EIF4G1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:93,726,322...93,746,387
|
|
G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr10:91,826,663...91,920,976
|
|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases expression |
ISO |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] lycopene results in increased expression of ESR1 mRNA |
CTD |
PMID:16886892 PMID:17051425 |
|
NCBI chr 1:43,511,685...43,904,454
|
|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr 6:100,589,553...100,645,240
|
|
G |
Fancc |
FA complementation group C |
decreases expression |
ISO |
lycopene results in decreased expression of FANCC mRNA |
CTD |
PMID:16886892 |
|
NCBI chr17:1,686,374...1,818,672
|
|
G |
Fancf |
FA complementation group F |
decreases expression |
ISO |
lycopene results in decreased expression of FANCF mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:110,585,054...110,587,870
|
|
G |
Faslg |
Fas ligand |
decreases expression |
ISO |
lycopene results in decreased expression of FASLG mRNA |
CTD |
PMID:16886892 |
|
NCBI chr13:76,680,885...76,706,042
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
lycopene results in increased expression of FOS mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLC mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLC mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GCLM protein Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] |
CTD |
PMID:35917956 PMID:36216167 |
|
NCBI chr 2:213,032,135...213,052,192
|
|
G |
Get1 |
guided entry of tail-anchored proteins factor 1 |
decreases expression |
ISO |
Lycopene results in decreased expression of GET1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:48,915,298...48,929,235
|
|
G |
Gfap |
glial fibrillary acidic protein |
decreases expression multiple interactions |
ISO EXP |
lycopene results in decreased expression of GFAP mRNA Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein] |
CTD |
PMID:19555370 PMID:32544411 |
|
NCBI chr10:88,352,987...88,361,661
|
|
G |
Gja1 |
gap junction protein, alpha 1 |
increases expression multiple interactions |
ISO EXP |
lycopene results in increased expression of GJA1 protein Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein] |
CTD |
PMID:16091010 PMID:31568845 |
|
NCBI chr20:36,302,490...36,315,010
|
|
G |
Gja4 |
gap junction protein, alpha 4 |
decreases expression |
ISO |
lycopene results in decreased expression of GJA4 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 5:144,917,791...144,920,324
|
|
G |
Gja5 |
gap junction protein, alpha 5 |
decreases expression increases expression |
ISO |
lycopene results in decreased expression of GJA5 mRNA lycopene results in increased expression of GJA5 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 2:187,291,227...187,310,770
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX1 mRNA] Lycopene results in increased expression of GPX1 mRNA [Glucose co-treated with Lycopene] results in increased expression of GPX1 mRNA |
CTD |
PMID:36216167 PMID:38444079 |
|
NCBI chr 8:117,905,462...117,906,588
|
|
G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX2 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 6:101,226,745...101,230,033
|
|
G |
Gpx3 |
glutathione peroxidase 3 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GPX3 mRNA Lycopene affects the reaction [Atrazine affects the expression of GPX3 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr10:39,529,335...39,537,406
|
|
G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO |
lycopene results in decreased expression of GPX4 mRNA Lycopene affects the reaction [Atrazine affects the expression of GPX4 mRNA] |
CTD |
PMID:16886892 PMID:36216167 |
|
NCBI chr 7:10,300,833...10,303,629
|
|
G |
Gpx5 |
glutathione peroxidase 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX5 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr17:48,131,853...48,138,801
|
|
G |
Gpx6 |
glutathione peroxidase 6 |
increases expression |
ISO |
Lycopene results in increased expression of GPX6 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr17:48,104,197...48,111,816
|
|
G |
Gpx7 |
glutathione peroxidase 7 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GPX7 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of GPX7 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 5:128,373,881...128,381,866
|
|
G |
Gpx8 |
glutathione peroxidase 8 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of GPX8 mRNA Lycopene inhibits the reaction [Atrazine results in decreased expression of GPX8 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 2:46,409,646...46,413,401
|
|
G |
Gsdmd |
gasdermin D |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSDMD protein] |
CTD |
PMID:36610486 |
|
NCBI chr 7:109,423,209...109,427,771
|
|
G |
Gsr |
glutathione-disulfide reductase |
multiple interactions |
ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] |
CTD |
PMID:25682699 |
|
NCBI chr16:65,185,574...65,228,742
|
|
G |
Gss |
glutathione synthetase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] |
CTD |
PMID:35917956 PMID:36610486 |
|
NCBI chr 3:164,508,005...164,538,343
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions increases expression |
EXP |
[Glucose co-treated with Lycopene] results in increased expression of GSTP1 mRNA Lycopene results in increased expression of GSTP1 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Hmgb1 |
high mobility group box 1 |
multiple interactions decreases response to substance |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein] lycopene results in decreased susceptibility to HMGB1 protein |
CTD |
PMID:22429818 |
|
NCBI chr12:11,009,236...11,015,941
|
|
G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA] [lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
|
|
NCBI chr19:13,452,365...13,479,823
|
|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] |
CTD |
PMID:19071209 |
|
NCBI chr 2:188,858,574...188,864,694
|
|
G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
multiple interactions |
EXP |
lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] |
CTD |
PMID:23076637 |
|
NCBI chr10:37,908,866...37,951,994
|
|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 3:38,453,016...38,457,475
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
|
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased expression of IGF1 mRNA lycopene results in increased expression of IGF1 mRNA |
CTD |
PMID:15084515 PMID:16565789 PMID:16886892 |
|
NCBI chr 7:24,169,608...24,249,446
|
|
G |
Igf1r |
insulin-like growth factor 1 receptor |
decreases expression |
ISO |
lycopene results in decreased expression of IGF1R protein |
CTD |
PMID:17337101 |
|
NCBI chr 1:130,959,787...131,248,664
|
|
G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
increases expression |
ISO |
lycopene results in increased expression of IGFBP2 protein |
CTD |
PMID:17337101 |
|
NCBI chr 9:81,864,811...81,892,179
|
|
G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] Lycopene inhibits the reaction [Atrazine results in decreased expression of IL10 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL10 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL10] |
CTD |
PMID:25551565 PMID:25682699 PMID:36216167 PMID:36583613 |
|
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] |
CTD |
PMID:36610486 |
|
NCBI chr 8:59,802,072...59,829,275
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B] |
CTD |
PMID:25682699 PMID:28974442 PMID:36216167 PMID:36610486 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] |
CTD |
PMID:25682699 |
|
NCBI chr 2:121,932,968...121,937,672
|
|
G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
EXP ISO |
lycopene results in decreased expression of IL6 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6] |
CTD |
PMID:15084515 PMID:25682699 PMID:36216167 PMID:36583613 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Irf3 |
interferon regulatory factor 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 1:104,616,608...104,621,402
|
|
G |
Irf7 |
interferon regulatory factor 7 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF7 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr 1:205,796,956...205,800,543
|
|
G |
Ivl |
involucrin |
decreases expression |
ISO |
lycopene results in decreased expression of IVL protein |
CTD |
PMID:10769631 |
|
NCBI chr 2:180,842,307...180,854,646
|
|
G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
lycopene results in increased expression of JAK1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 5:120,895,606...121,004,207
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
lycopene results in decreased expression of JUN mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of KEAP1 protein] Lycopene results in increased expression of KEAP1 mRNA |
CTD |
PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
|
NCBI chr 8:28,044,555...28,054,042
|
|
G |
Kif2a |
kinesin family member 2A |
increases expression |
ISO |
lycopene results in increased expression of KIF2A mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 2:40,101,548...40,164,780
|
|
G |
Kpna2 |
karyopherin subunit alpha 2 |
increases expression |
ISO |
lycopene results in increased expression of KPNA2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr10:92,433,678...92,445,841
|
|
G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
lycopene results in increased expression of LDLR mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 8:28,546,191...28,569,075
|
|
G |
Lipa |
lipase A, lysosomal acid type |
increases expression |
ISO |
lycopene results in increased expression of LIPA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:241,437,524...241,470,936
|
|
G |
Lpo |
lactoperoxidase |
multiple interactions |
ISO |
lycopene inhibits the reaction [Diethylnitrosamine results in increased expression of LPO protein] |
CTD |
PMID:24144777 |
|
NCBI chr10:73,104,170...73,124,683
|
|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased localization of MAP1LC3B protein] [Glucose co-treated with Lycopene] results in increased expression of MAP1LC3B mRNA |
CTD |
PMID:36583613 PMID:38444079 |
|
NCBI chr19:66,571,631...66,582,270
|
|
G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression |
ISO |
lycopene results in increased expression of MAP2K1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 8:73,578,747...73,650,184
|
|
G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K2 protein |
CTD |
PMID:17337101 |
|
NCBI chr 7:9,241,449...9,264,216
|
|
G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K4 protein |
CTD |
PMID:17337101 |
|
NCBI chr10:50,842,348...50,947,063
|
|
G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K6 protein |
CTD |
PMID:17337101 |
|
NCBI chr10:95,872,747...95,987,747
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases expression |
EXP ISO |
Lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK1 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of MAPK1 protein] Lycopene results in increased expression of MAPK1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of MAPK1 mRNA] |
CTD |
PMID:19551842 PMID:30360616 PMID:32153214 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
decreases expression multiple interactions increases expression |
ISO EXP |
lycopene results in decreased expression of MAPK14 protein Lycopene inhibits the reaction [Oxaliplatin results in increased expression of MAPK14 protein] lycopene results in increased expression of MAPK14 mRNA |
CTD |
PMID:16886892 PMID:17337101 PMID:32544411 |
|
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases expression |
ISO |
lycopene results in decreased expression of MAPK3 protein |
CTD |
PMID:17337101 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
decreases expression |
ISO |
lycopene results in decreased expression of MAPK8 protein |
CTD |
PMID:17337101 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mgat2 |
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
increases expression |
ISO |
lycopene results in increased expression of MGAT2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:93,392,416...93,394,905
|
|
G |
Mill1 |
MHC I like leukocyte 1 |
increases expression |
ISO |
Lycopene results in increased expression of MICA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:87,500,591...87,526,983
|
|
G |
Mki67 |
marker of proliferation Ki-67 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of MKI67 protein] |
CTD |
PMID:33592256 |
|
NCBI chr 1:199,926,150...199,952,847
|
|
G |
Mlh1 |
mutL homolog 1 |
increases expression |
ISO |
lycopene results in increased expression of MLH1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 8:120,074,871...120,112,109
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Acetaminophen results in increased activity of MMP2 protein] |
CTD |
PMID:27989599 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Msh2 |
mutS homolog 2 |
increases expression |
ISO |
lycopene results in increased expression of MSH2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:12,567,368...12,626,534
|
|
G |
Msh6 |
mutS homolog 6 |
increases expression |
ISO |
lycopene results in increased expression of MSH6 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:12,316,190...12,333,505
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
EXP ISO |
lycopene results in increased expression of NFE2L2 mRNA; lycopene results in increased expression of NFE2L2 protein Lycopene inhibits the reaction [Atrazine affects the localization of NFE2L2 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein] lycopene promotes the reaction [Atrazine results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
|
|
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine results in increased expression of NFKB1 mRNA] |
CTD |
PMID:27102619 |
|
NCBI chr 2:226,689,745...226,805,897
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] |
CTD |
PMID:25551565 |
|
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] |
CTD |
PMID:36610486 |
|
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nos1 |
nitric oxide synthase 1 |
decreases expression |
ISO |
lycopene results in decreased expression of NOS1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr12:44,276,011...44,456,371
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] |
CTD |
PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
|
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Lycopene increases expression of NR1H3 protein in macrophages |
RGD |
PMID:21208793 |
RGD:401842374 |
NCBI chr 3:97,614,616...97,632,053
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein] Lycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 protein |
CTD |
PMID:36216167 PMID:36403809 |
|
NCBI chr11:75,965,717...76,006,733
|
|
G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions increases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 protein] Lycopene results in increased expression of NR1I3 mRNA |
CTD |
PMID:36216167 PMID:36403809 |
|
NCBI chr13:86,165,327...86,170,362
|
|
G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
multiple interactions |
ISO |
[Lycopene co-treated with Atrazine] results in increased expression of NR3C2 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr19:47,619,853...47,964,089
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of NTRK2 protein Lycopene inhibits the reaction [bisphenol A results in decreased expression of NTRK2 protein] |
CTD |
PMID:32153214 |
|
NCBI chr17:5,560,558...5,875,899
|
|
G |
Nup214 |
nucleoporin 214 |
decreases expression |
ISO |
lycopene results in decreased expression of NUP214 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 3:35,652,841...35,738,323
|
|
G |
Nup62 |
nucleoporin 62 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NUP62 mRNA] |
CTD |
PMID:35917956 |
|
NCBI chr 1:104,435,532...104,451,392
|
|
G |
P22k15 |
cystatin related protein 2 |
decreases expression |
EXP |
lycopene results in decreased expression of P22K15 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 3:157,420,930...157,427,988
|
|
G |
Pah |
phenylalanine hydroxylase |
decreases expression |
ISO |
lycopene results in decreased expression of PAH mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 7:23,793,096...23,885,631
|
|
G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] |
CTD |
PMID:23076637 |
|
NCBI chr13:94,839,484...94,871,295
|
|
G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP |
lycopene inhibits the reaction [[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PCNA protein] |
CTD |
PMID:19551842 |
|
NCBI chr 3:139,951,948...139,955,820
|
|
G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 5:155,813,838...155,825,950
|
|
G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein] |
CTD |
PMID:22429818 |
|
NCBI chr 5:156,359,725...156,362,302
|
|
G |
Pomc |
proopiomelanocortin |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine results in increased secretion of POMC protein modified form] |
CTD |
PMID:27102619 |
|
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of PPARA mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of PPARA protein] |
CTD |
PMID:36216167 |
|
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of PPARG mRNA [Lycopene co-treated with Atrazine] results in increased expression of PPARG mRNA |
CTD |
PMID:36216167 |
|
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX1 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 5:135,383,906...135,399,504
|
|
G |
Prdx2 |
peroxiredoxin 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX2 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr19:40,085,788...40,091,083
|
|
G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions increases expression increases phosphorylation |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAA2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased phosphorylation of PRKAA2 protein] Lycopene results in increased expression of PRKAA2 mRNA Lycopene results in increased phosphorylation of PRKAA2 protein |
CTD |
PMID:30360616 |
|
NCBI chr 5:125,036,945...125,109,010
|
|
G |
Prkab1 |
protein kinase AMP-activated non-catalytic subunit beta 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAB1 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr12:46,248,971...46,259,487
|
|
G |
Prkab2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of PRKAB2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:187,946,008...187,961,615
|
|
G |
Prkag2 |
protein kinase AMP-activated non-catalytic subunit gamma 2 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine results in increased expression of PRKAG2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 4:10,744,695...10,985,939
|
|
G |
Prkdc |
protein kinase, DNA-activated, catalytic subunit |
decreases expression |
ISO |
lycopene results in decreased expression of PRKDC mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:98,544,952...98,762,499
|
|
G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] |
CTD |
PMID:36583613 |
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NCBI chr 1:51,236,410...52,430,242
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|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of PTGS2 mRNA]; Lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA] |
CTD |
PMID:28974442 PMID:36216167 |
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NCBI chr13:64,714,063...64,722,320
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|
G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD protein] |
CTD |
PMID:36610486 |
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NCBI chr 1:192,032,124...192,033,419
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|
G |
Rad50 |
RAD50 double strand break repair protein |
increases expression |
ISO |
lycopene results in increased expression of RAD50 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr10:38,310,147...38,362,100
|
|
G |
Rassf7 |
Ras association domain family member 7 |
increases expression |
ISO |
lycopene results in increased expression of RASSF7 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:205,749,173...205,753,350
|
|
G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions decreases phosphorylation |
ISO |
lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 |
|
NCBI chr15:54,780,858...54,911,989
|
|
G |
Rdx |
radixin |
decreases expression |
ISO |
lycopene results in decreased expression of RDX mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 8:61,275,792...61,348,260
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein] |
CTD |
PMID:36583613 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions |
EXP |
[Glucose co-treated with Lycopene] results in increased expression of RIPK1 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr17:31,044,983...31,077,167
|
|
G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
multiple interactions |
EXP |
[Glucose co-treated with Lycopene] results in increased expression of RIPK3 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr15:33,253,071...33,262,025
|
|
G |
Rps6ka1 |
ribosomal protein S6 kinase A1 |
decreases expression |
ISO |
lycopene results in decreased expression of RPS6KA1 protein |
CTD |
PMID:17337101 |
|
NCBI chr 5:151,362,819...151,402,064
|
|
G |
Rps6ka3 |
ribosomal protein S6 kinase A3 |
decreases expression |
ISO |
lycopene results in decreased expression of RPS6KA3 protein |
CTD |
PMID:17337101 |
|
NCBI chr X:39,325,926...39,432,017
|
|
G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
increases expression |
ISO |
lycopene results in increased expression of RRM2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 6:47,044,755...47,075,370
|
|
G |
Sbp |
spermine binding protein |
decreases expression |
EXP |
lycopene results in decreased expression of SBP mRNA |
CTD |
PMID:15084515 |
|
NCBI chr10:13,450,613...13,473,016
|
|
G |
Scgb1d2 |
secretoglobin, family 1D, member 2 |
decreases expression |
EXP |
lycopene results in decreased expression of SCGB1D2 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 1:215,653,464...215,658,101
|
|
G |
Scgb1d4 |
secretoglobin family 1D member 4 |
decreases expression |
EXP |
lycopene results in decreased expression of SCGB1D4 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 1:215,755,363...215,758,238
|
|
G |
Sele |
selectin E |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
|
NCBI chr13:78,935,997...78,945,905
|
|
G |
Selenop |
selenoprotein P |
decreases expression |
ISO |
lycopene results in decreased expression of SELENOP mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 2:54,225,736...54,236,022
|
|
G |
Selenos |
selenoprotein S |
increases expression |
EXP |
Lycopene results in increased expression of SELENOS mRNA |
CTD |
PMID:38444079 |
|
NCBI chr 1:129,070,240...129,080,007
|
|
G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein] |
CTD |
PMID:28974442 |
|
NCBI chr20:25,305,953...25,328,000
|
|
G |
Skap2 |
src kinase associated phosphoprotein 2 |
decreases expression |
ISO |
lycopene results in decreased expression of SKAP2 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 4:82,281,221...82,431,664
|
|
G |
Smad3 |
SMAD family member 3 |
increases expression |
ISO |
lycopene results in increased expression of SMAD3 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 8:73,022,204...73,132,324
|
|
G |
Smc1a |
structural maintenance of chromosomes 1A |
decreases expression |
ISO |
lycopene results in decreased expression of SMC1A mRNA |
CTD |
PMID:16886892 |
|
NCBI chr X:24,582,732...24,627,462
|
|
G |
Sod1 |
superoxide dismutase 1 |
multiple interactions increases expression |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 mRNA]; Lycopene promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein] [Glucose co-treated with Lycopene] results in increased expression of SOD1 mRNA Lycopene results in increased expression of SOD1 mRNA |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 |
|
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 protein] Lycopene results in increased expression of SOD2 mRNA [Glucose co-treated with Lycopene] results in increased expression of SOD2 mRNA |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sod3 |
superoxide dismutase 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD3 mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
|
NCBI chr14:62,822,865...62,828,602
|
|
G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein] [Glucose co-treated with Lycopene] results in increased expression of SQSTM1 mRNA |
CTD |
PMID:30360616 PMID:36583613 PMID:38444079 |
|
NCBI chr10:35,026,598...35,037,750
|
|
G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases expression |
EXP |
lycopene results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 1:35,514,914...35,548,898
|
|
G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
EXP |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of STAR protein]; lycopene inhibits the reaction [decamethrin results in decreased expression of STAR mRNA] |
CTD |
PMID:19071209 PMID:23076637 |
|
NCBI chr16:72,969,824...72,974,447
|
|
G |
Stat3 |
signal transducer and activator of transcription 3 |
increases expression |
ISO |
lycopene results in increased expression of STAT3 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr10:86,311,528...86,363,513
|
|
G |
Sting1 |
stimulator of interferon response cGAMP interactor 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr18:27,606,196...27,612,544
|
|
G |
Tbk1 |
TANK-binding kinase 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of TBK1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 7:58,963,319...58,996,357
|
|
G |
Tff1 |
trefoil factor 1 |
decreases expression |
ISO |
lycopene results in decreased expression of TFF1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr20:9,237,095...9,240,956
|
|
G |
Tfpi2 |
tissue factor pathway inhibitor 2 |
decreases expression |
ISO |
lycopene results in decreased expression of TFPI2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 4:32,936,462...32,941,385
|
|
G |
Tgfa |
transforming growth factor alpha |
increases expression |
ISO |
lycopene results in increased expression of TGFA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 4:120,175,549...120,258,342
|
|
G |
Tlr2 |
toll-like receptor 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] |
CTD |
PMID:22429818 |
|
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] Lycopene affects the reaction [Atrazine affects the expression of TLR4 mRNA] |
CTD |
PMID:22429818 PMID:36216167 |
|
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP ISO |
[Lycopene co-treated with Diethylnitrosamine] results in increased expression of TNF mRNA; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of TNF protein] Lycopene inhibits the reaction [Atrazine results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TNF protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF] [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] |
CTD |
PMID:19551842 PMID:22429818 PMID:25551565 PMID:25682699 PMID:28974442 PMID:32544411 PMID:36216167 PMID:36583613 More...
|
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Tp53 |
tumor protein p53 |
decreases expression multiple interactions |
ISO |
lycopene results in decreased expression of TP53 mRNA Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA] |
CTD |
PMID:16886892 PMID:36583613 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 protein] |
CTD |
PMID:36216167 |
|
NCBI chr 3:108,418,537...108,443,330
|
|
G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TSHB protein] |
CTD |
PMID:33592256 |
|
NCBI chr 2:192,913,171...192,918,054
|
|
G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
Lycopene affects the reaction [Atrazine affects the expression of TXN1 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 5:77,507,455...77,519,685
|
|
G |
Txn2 |
thioredoxin 2 |
multiple interactions decreases expression |
ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of TXN2 mRNA] Lycopene results in decreased expression of TXN2 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr 7:111,377,338...111,390,940
|
|
G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:22429818 |
|
NCBI chr 2:206,723,050...206,742,783
|
|
G |
Vcp |
valosin-containing protein |
increases expression |
ISO |
lycopene results in increased expression of VCP mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 5:62,005,984...62,025,387
|
|
G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of VEGFA protein] |
CTD |
PMID:33592256 |
|
NCBI chr 9:22,452,854...22,468,194
|
|
G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr14:84,604,623...84,609,707
|
|