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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] |
CTD |
PMID:17051425 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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|
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] |
CTD |
PMID:17051425 |
|
NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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|
G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions |
ISO |
[(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
|
NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
ISO |
Lycopene inhibits the reaction [bisphenol A results in decreased activity of ACE protein] |
CTD |
PMID:32153214 |
|
NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
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G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] |
CTD |
PMID:22192907 PMID:26900785 |
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NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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G |
Acvr2b |
activin receptor IIB |
decreases expression |
ISO |
Lycopene results in decreased expression of SCGB2A2 mRNA |
CTD |
PMID:15084515 |
|
NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061
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G |
Add1 |
adducin 1 |
decreases expression |
ISO |
lycopene results in decreased expression of ADD1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 5:34,731,008...34,789,652
Ensembl chr 5:34,731,008...34,789,652
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] |
CTD |
PMID:22429818 |
|
NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
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G |
Ahr |
aryl-hydrocarbon receptor |
decreases expression multiple interactions |
ISO EXP |
lycopene results in decreased expression of AHR mRNA [Lycopene co-treated with Atrazine] results in increased expression of AHR mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of AHR protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of AHR protein] |
CTD |
PMID:16886892 PMID:34670089 PMID:36216167 PMID:36403809 |
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NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] |
CTD |
PMID:28974442 |
|
NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044
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G |
Akt1 |
thymoma viral proto-oncogene 1 |
decreases phosphorylation |
ISO |
lycopene results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:17337101 |
|
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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G |
Alad |
aminolevulinate, delta-, dehydratase |
multiple interactions |
EXP ISO |
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein] lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein] |
CTD |
PMID:17516994 PMID:25682699 |
|
NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155
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G |
Aqp1 |
aquaporin 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of AQP1 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
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G |
Aqp11 |
aquaporin 11 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP11 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 7:97,375,586...97,387,454
Ensembl chr 7:97,373,213...97,387,496
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G |
Aqp2 |
aquaporin 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of AQP2 protein] |
CTD |
PMID:33960999 |
|
NCBI chr15:99,476,937...99,482,426
Ensembl chr15:99,476,936...99,482,428
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G |
Aqp4 |
aquaporin 4 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP4 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
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G |
Aqp6 |
aquaporin 6 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP6 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr15:99,495,891...99,503,359
Ensembl chr15:99,499,281...99,503,358
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G |
Aqp7 |
aquaporin 7 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of AQP7 mRNA] |
CTD |
PMID:33960999 |
|
NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
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G |
Ar |
androgen receptor |
decreases expression |
ISO |
lycopene results in decreased expression of AR mRNA |
CTD |
PMID:16886892 |
|
NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions increases expression |
EXP |
[Diethylhexyl Phthalate co-treated with Lycopene] results in decreased expression of ARNT mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of ARNT protein] Lycopene results in increased expression of ARNT mRNA |
CTD |
PMID:34670089 PMID:36216167 PMID:36403809 |
|
NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
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G |
Atg10 |
autophagy related 10 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr13:91,083,467...91,372,189
Ensembl chr13:91,083,475...91,372,087
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G |
Atg13 |
autophagy related 13 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921
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G |
Atg14 |
autophagy related 14 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106
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G |
Atg16l1 |
autophagy related 16 like 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 1:87,683,730...87,720,150
Ensembl chr 1:87,683,592...87,720,150
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G |
Atg16l2 |
autophagy related 16 like 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 7:100,935,521...100,951,474
Ensembl chr 7:100,912,241...100,951,458
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G |
Atg2b |
autophagy related 2B |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr12:105,579,798...105,651,554
Ensembl chr12:105,582,395...105,651,470
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G |
Atg3 |
autophagy related 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr16:44,979,192...45,008,901
Ensembl chr16:44,979,148...45,008,901
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G |
Atg4a |
autophagy related 4A, cysteine peptidase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr X:139,854,594...139,947,190
Ensembl chr X:139,857,656...139,947,266
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G |
Atg4b |
autophagy related 4B, cysteine peptidase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 1:93,682,627...93,717,328
Ensembl chr 1:93,679,222...93,718,332
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G |
Atg4c |
autophagy related 4C, cysteine peptidase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 4:99,077,181...99,185,495
Ensembl chr 4:99,082,171...99,148,024
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
EXP ISO |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA] [Glucose co-treated with Lycopene] results in increased expression of ATG5 mRNA |
CTD |
PMID:30360616 PMID:38444079 |
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NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575
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G |
Atg9a |
autophagy related 9A |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840
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G |
Atg9b |
autophagy related 9B |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 5:24,589,179...24,597,141
Ensembl chr 5:24,589,179...24,597,141
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G |
Atp1a1 |
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
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NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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G |
Atp1a2 |
ATPase, Na+/K+ transporting, alpha 2 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr 1:172,099,276...172,125,631
Ensembl chr 1:172,099,276...172,125,631
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G |
Atp1a3 |
ATPase, Na+/K+ transporting, alpha 3 polypeptide |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr 7:24,677,592...24,705,338
Ensembl chr 7:24,677,592...24,705,383
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G |
Atp1a4 |
ATPase, Na+/K+ transporting, alpha 4 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 1:172,051,075...172,085,991
Ensembl chr 1:172,051,080...172,085,981
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G |
Atp1b1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
|
NCBI chr 1:164,264,668...164,285,924
Ensembl chr 1:164,264,678...164,285,924
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G |
Atp1b2 |
ATPase, Na+/K+ transporting, beta 2 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
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NCBI chr11:69,490,554...69,496,786
Ensembl chr11:69,490,562...69,496,768
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G |
Atp1b3 |
ATPase, Na+/K+ transporting, beta 3 polypeptide |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] |
CTD |
PMID:26476475 |
|
NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495
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G |
Atp1b4 |
ATPase Na+/K+ transporting, beta 4 polypeptide |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] |
CTD |
PMID:26476475 PMID:33960999 |
|
NCBI chr X:37,404,999...37,425,661
Ensembl chr X:37,405,061...37,425,646
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G |
Atp2a1 |
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] |
CTD |
PMID:27112537 |
|
NCBI chr 7:126,045,032...126,062,245
Ensembl chr 7:126,045,030...126,062,280
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G |
Atp2a2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A2 mRNA] |
CTD |
PMID:27112537 PMID:33960999 |
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NCBI chr 5:122,591,576...122,640,288
Ensembl chr 5:122,591,576...122,640,288
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G |
Atp2a3 |
ATPase, Ca++ transporting, ubiquitous |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2A3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
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G |
Atp2b1 |
ATPase, Ca++ transporting, plasma membrane 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2B1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005
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G |
Atp2b2 |
ATPase, Ca++ transporting, plasma membrane 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574
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G |
Atp2b3 |
ATPase, Ca++ transporting, plasma membrane 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr X:72,546,356...72,632,267
Ensembl chr X:72,546,692...72,614,611
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G |
Atp2b4 |
ATPase, Ca++ transporting, plasma membrane 4 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] |
CTD |
PMID:26476475 PMID:27112537 |
|
NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779
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G |
Atp2c1 |
ATPase, Ca++-sequestering |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP2C1 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
|
NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518
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G |
Atp2c2 |
ATPase, Ca++ transporting, type 2C, member 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] |
CTD |
PMID:26476475 PMID:27112537 PMID:33960999 |
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NCBI chr 8:120,426,748...120,484,457
Ensembl chr 8:120,426,748...120,484,456
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G |
Bach1 |
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
increases expression |
ISO |
lycopene results in increased expression of BACH1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAK1 protein] |
CTD |
PMID:36583613 |
|
NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983
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G |
Bap1 |
Brca1 associated protein 1 |
increases expression |
ISO |
lycopene results in increased expression of BAP1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901
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G |
Bax |
BCL2-associated X protein |
multiple interactions |
ISO EXP |
Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA] Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA] |
CTD |
PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:36583613 |
|
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] |
CTD |
PMID:26900785 |
|
NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
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G |
Bcl2 |
B cell leukemia/lymphoma 2 |
multiple interactions increases expression |
ISO EXP |
[Glucose co-treated with Lycopene] results in increased expression of BCL2 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA] lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA] Lycopene results in increased expression of BCL2 mRNA |
CTD |
PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 PMID:32153214 PMID:38444079 More...
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NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
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G |
Bco1 |
beta-carotene oxygenase 1 |
multiple interactions |
EXP |
BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] |
CTD |
PMID:21935922 |
|
NCBI chr 8:117,822,590...117,860,459
Ensembl chr 8:117,822,593...117,860,459
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G |
Bdnf |
brain derived neurotrophic factor |
multiple interactions |
EXP ISO |
Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein] Lycopene inhibits the reaction [bisphenol A results in decreased expression of BDNF protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein] |
CTD |
PMID:28974442 PMID:32153214 PMID:32544411 |
|
NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
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G |
Becn1 |
beclin 1, autophagy related |
multiple interactions |
EXP ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA] [Glucose co-treated with Lycopene] results in increased expression of BECN1 mRNA |
CTD |
PMID:30360616 PMID:38444079 |
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NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
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G |
Braf |
Braf transforming gene |
decreases expression |
ISO |
lycopene results in decreased expression of BRAF protein |
CTD |
PMID:17337101 |
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NCBI chr 6:39,580,171...39,702,592
Ensembl chr 6:39,580,171...39,702,397
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G |
C1qa |
complement component 1, q subcomponent, alpha polypeptide |
decreases expression |
EXP |
lycopene results in decreased expression of C1QA mRNA |
CTD |
PMID:19555370 |
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NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114
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G |
C4b |
complement C4B (Chido blood group) |
decreases expression |
EXP |
lycopene results in decreased expression of C4B mRNA |
CTD |
PMID:19555370 |
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NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856
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G |
Calca |
calcitonin/calcitonin-related polypeptide, alpha |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] |
CTD |
PMID:33592256 |
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NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
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G |
Casp1 |
caspase 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP1 protein] |
CTD |
PMID:36610486 |
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NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
[Glucose co-treated with Lycopene] results in increased expression of CASP3 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA] |
CTD |
PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32153214 PMID:32544411 PMID:36583613 PMID:38444079 More...
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NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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G |
Casp8 |
caspase 8 |
multiple interactions decreases expression |
ISO |
[Glucose co-treated with Lycopene] results in increased expression of CASP8 mRNA; [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein] lycopene results in decreased expression of CASP8 mRNA |
CTD |
PMID:16030430 PMID:16886892 PMID:38444079 |
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NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO EXP |
[Glucose co-treated with Lycopene] results in increased expression of CASP9 mRNA; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] |
CTD |
PMID:27871895 PMID:38444079 |
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NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
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G |
Cat |
catalase |
multiple interactions decreases expression increases activity increases expression |
ISO EXP |
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA] Lycopene results in decreased expression of CAT mRNA Lycopene affects the reaction [Atrazine affects the expression of CAT mRNA]; Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CAT protein] lycopene results in increased activity of CAT protein lycopene results in increased expression of CAT |
CTD |
PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 PMID:26900785 PMID:27102619 PMID:27989599 PMID:30360616 PMID:31568845 PMID:32544411 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL4 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CCL5 mRNA] |
CTD |
PMID:36583613 |
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NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression |
ISO |
lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein] lycopene results in decreased expression of CCND1 protein lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein] |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 |
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NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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G |
Ccne1 |
cyclin E1 |
decreases expression increases expression |
ISO |
lycopene results in decreased expression of CCNE1 protein lycopene results in increased expression of CCNE1 mRNA |
CTD |
PMID:16886892 PMID:17337101 |
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NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
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G |
Ccs |
copper chaperone for superoxide dismutase |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of CCS mRNA [Glucose co-treated with Lycopene] results in increased expression of CCS mRNA |
CTD |
PMID:38444079 |
|
NCBI chr19:4,875,394...4,889,326
Ensembl chr19:4,875,394...4,889,360
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G |
Cdk1 |
cyclin dependent kinase 1 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK1 protein |
CTD |
PMID:17337101 |
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NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
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G |
Cdk4 |
cyclin dependent kinase 4 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK4 protein |
CTD |
PMID:17337101 |
|
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
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G |
Cdk5 |
cyclin dependent kinase 5 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK5 protein |
CTD |
PMID:17337101 |
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NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528
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G |
Cdk7 |
cyclin dependent kinase 7 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK7 protein |
CTD |
PMID:17337101 |
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NCBI chr13:100,833,532...100,867,454
Ensembl chr13:100,839,139...100,867,447
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G |
Cdk9 |
cyclin dependent kinase 9 |
decreases expression |
ISO |
lycopene results in decreased expression of CDK9 protein |
CTD |
PMID:17337101 |
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NCBI chr 2:32,595,794...32,608,098
Ensembl chr 2:32,595,796...32,603,088
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G |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
multiple interactions |
ISO |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] |
CTD |
PMID:16565789 |
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NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
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G |
Cgas |
cyclic GMP-AMP synthase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CGAS protein] |
CTD |
PMID:36583613 |
|
NCBI chr 9:78,337,800...78,350,519
Ensembl chr 9:78,337,808...78,350,519
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G |
Chga |
chromogranin A |
increases expression |
ISO |
lycopene results in increased expression of CHGA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287
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G |
Chgb |
chromogranin B |
decreases expression |
ISO |
lycopene results in decreased expression of CHGB mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 2:132,623,562...132,636,999
Ensembl chr 2:132,623,198...132,636,999
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G |
Ckb |
creatine kinase, brain |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] |
CTD |
PMID:26900785 |
|
NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
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G |
Crb1 |
crumbs family member 1, photoreceptor morphogenesis associated |
decreases expression |
ISO |
lycopene results in decreased expression of CRB1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 1:139,101,288...139,307,262
Ensembl chr 1:139,124,794...139,304,838
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of CREB1 protein Lycopene inhibits the reaction [bisphenol A results in decreased expression of CREB1 protein] |
CTD |
PMID:32153214 |
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NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
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G |
Csf2 |
colony stimulating factor 2 (granulocyte-macrophage) |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CSF2 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
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G |
Csprs |
component of Sp100-rs |
decreases expression |
EXP |
lycopene results in decreased expression of CSPRS mRNA |
CTD |
PMID:19555370 |
|
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G |
Ctss |
cathepsin S |
decreases expression |
EXP |
lycopene results in decreased expression of CTSS mRNA |
CTD |
PMID:19555370 |
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NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL10 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
decreases expression |
EXP |
lycopene results in decreased expression of CXCL14 mRNA |
CTD |
PMID:19555370 |
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NCBI chr13:56,436,456...56,444,624
Ensembl chr13:56,436,456...56,444,364
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G |
Cxcl15 |
C-X-C motif chemokine ligand 15 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] |
CTD |
PMID:25551565 |
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NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CXCL2 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
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G |
Cyb5a |
cytochrome b5 type A (microsomal) |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] |
CTD |
PMID:26775023 |
|
NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996
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G |
Cygb |
cytoglobin |
increases expression |
ISO |
Lycopene results in increased expression of CYGB mRNA |
CTD |
PMID:38444079 |
|
NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] |
CTD |
PMID:19071209 |
|
NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
decreases activity multiple interactions |
EXP |
lycopene results in decreased activity of CYP1A1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A1 protein] |
CTD |
PMID:19329757 PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 |
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NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases expression |
EXP |
[Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1A2 protein] Lycopene results in increased expression of CYP1A2 mRNA |
CTD |
PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 |
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NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity multiple interactions increases expression |
EXP |
lycopene results in decreased activity of CYP1B1 protein [Lycopene co-treated with Atrazine] results in increased expression of CYP1B1 mRNA; Lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP1B1 protein] Lycopene results in increased expression of CYP1B1 mRNA |
CTD |
PMID:19329757 PMID:26775023 PMID:34670089 PMID:36216167 PMID:36403809 |
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NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
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G |
Cyp2a4 |
cytochrome P450, family 2, subfamily a, polypeptide 4 |
multiple interactions |
EXP |
Lycopene affects the reaction [Atrazine affects the expression of CYP2A4 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2A4 mRNA] |
CTD |
PMID:26775023 PMID:36216167 |
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NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
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G |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
multiple interactions |
EXP |
Lycopene promotes the reaction [Atrazine results in increased expression of CYP2B10 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
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G |
Cyp2b9 |
cytochrome P450, family 2, subfamily b, polypeptide 9 |
multiple interactions |
EXP |
lycopene affects the reaction [Atrazine results in increased expression of CYP2B9 mRNA] |
CTD |
PMID:26775023 |
|
NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
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G |
Cyp2c29 |
cytochrome P450, family 2, subfamily c, polypeptide 29 |
multiple interactions |
EXP |
Lycopene affects the reaction [Atrazine results in increased expression of CYP2C29 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of CYP2E1 protein] |
CTD |
PMID:26775023 PMID:36216167 PMID:36403809 |
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NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
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G |
Cyp2f2 |
cytochrome P450, family 2, subfamily f, polypeptide 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2F2 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
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G |
Cyp2j5 |
cytochrome P450, family 2, subfamily j, polypeptide 5 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP2J5 mRNA] Lycopene results in increased expression of CYP2J5 mRNA |
CTD |
PMID:26775023 PMID:36216167 |
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NCBI chr 4:96,517,010...96,552,391
Ensembl chr 4:96,517,010...96,552,391
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G |
Cyp3a13 |
cytochrome P450, family 3, subfamily a, polypeptide 13 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A13 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
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G |
Cyp3a57 |
cytochrome P450, family 3, subfamily a, polypeptide 57 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP3A57 mRNA] |
CTD |
PMID:26775023 PMID:36216167 |
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NCBI chr 5:145,281,959...145,327,736
Ensembl chr 5:145,282,089...145,327,736
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G |
Cyp4a14 |
cytochrome P450, family 4, subfamily a, polypeptide 14 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4A14 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
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G |
Cyp4a31 |
cytochrome P450, family 4, subfamily a, polypeptide 31 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4A31 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr 4:115,420,824...115,436,212
Ensembl chr 4:115,420,846...115,436,212
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G |
Cyp4v3 |
cytochrome P450, family 4, subfamily v, polypeptide 3 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of CYP4V3 mRNA] Lycopene results in increased expression of CYP4V3 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr 8:45,758,838...45,786,200
Ensembl chr 8:45,757,981...45,786,253
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G |
Cyp7b1 |
cytochrome P450, family 7, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] |
CTD |
PMID:26775023 |
|
NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
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G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
lycopene results in increased expression of DDB2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 2:91,041,924...91,067,465
Ensembl chr 2:91,041,917...91,067,327
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G |
Dnm1l |
dynamin 1-like |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of DNM1L mRNA] |
CTD |
PMID:33908429 |
|
NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
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G |
Eif4g1 |
eukaryotic translation initiation factor 4, gamma 1 |
increases expression |
ISO |
lycopene results in increased expression of EIF4G1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634
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G |
Ern1 |
endoplasmic reticulum to nucleus signalling 1 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
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G |
Esr1 |
estrogen receptor 1 (alpha) |
multiple interactions increases expression |
ISO |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein] lycopene results in increased expression of ESR1 mRNA |
CTD |
PMID:16886892 PMID:17051425 |
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NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
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G |
Esr2 |
estrogen receptor 2 (beta) |
multiple interactions |
ISO |
lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] |
CTD |
PMID:17051425 |
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NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
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G |
Fancc |
Fanconi anemia, complementation group C |
decreases expression |
ISO |
lycopene results in decreased expression of FANCC mRNA |
CTD |
PMID:16886892 |
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NCBI chr13:63,452,519...63,645,126
Ensembl chr13:63,432,857...63,645,092
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G |
Fancf |
Fanconi anemia, complementation group F |
decreases expression |
ISO |
lycopene results in decreased expression of FANCF mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 7:51,510,325...51,512,015
Ensembl chr 7:51,510,325...51,512,015
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G |
Fasl |
Fas ligand |
decreases expression |
ISO |
lycopene results in decreased expression of FASLG mRNA |
CTD |
PMID:16886892 |
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NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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G |
Fos |
FBJ osteosarcoma oncogene |
increases expression |
ISO |
lycopene results in increased expression of FOS mRNA |
CTD |
PMID:16886892 |
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NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLC mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLC mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
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G |
Gclm |
glutamate-cysteine ligase, modifier subunit |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] Lycopene results in increased expression of GCLM protein |
CTD |
PMID:35917956 PMID:36216167 |
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NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
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G |
Get1 |
guided entry of tail-anchored proteins factor 1 |
decreases expression |
ISO |
Lycopene results in decreased expression of GET1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr16:95,946,600...95,959,052
Ensembl chr16:95,946,607...95,959,052
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G |
Gfap |
glial fibrillary acidic protein |
decreases expression multiple interactions |
EXP ISO |
lycopene results in decreased expression of GFAP mRNA Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein] |
CTD |
PMID:19555370 PMID:32544411 |
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NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
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G |
Gja1 |
gap junction protein, alpha 1 |
increases expression multiple interactions |
EXP ISO |
lycopene results in increased expression of GJA1 protein Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein] |
CTD |
PMID:16091010 PMID:31568845 |
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NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
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G |
Gja4 |
gap junction protein, alpha 4 |
decreases expression |
ISO |
lycopene results in decreased expression of GJA4 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 4:127,205,213...127,207,832
Ensembl chr 4:127,205,214...127,207,832
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G |
Gja5 |
gap junction protein, alpha 5 |
decreases expression increases expression |
ISO |
lycopene results in decreased expression of GJA5 mRNA lycopene results in increased expression of GJA5 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732
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G |
Gm38656 |
predicted gene, 38656 |
decreases expression |
ISO |
Lycopene results in decreased expression of SCGB1D2 mRNA |
CTD |
PMID:15084515 |
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NCBI chr19:9,162,589...9,164,383
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions increases expression |
EXP ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX1 mRNA] Lycopene results in increased expression of GPX1 mRNA [Glucose co-treated with Lycopene] results in increased expression of GPX1 mRNA |
CTD |
PMID:36216167 PMID:38444079 |
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NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX2 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of GPX3 mRNA Lycopene affects the reaction [Atrazine affects the expression of GPX3 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO EXP |
lycopene results in decreased expression of GPX4 mRNA Lycopene affects the reaction [Atrazine affects the expression of GPX4 mRNA] |
CTD |
PMID:16886892 PMID:36216167 |
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NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
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G |
Gpx5 |
glutathione peroxidase 5 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX5 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
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G |
Gpx6 |
glutathione peroxidase 6 |
increases expression |
EXP |
Lycopene results in increased expression of GPX6 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr13:21,479,635...21,503,795
Ensembl chr13:21,496,295...21,503,794
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G |
Gpx7 |
glutathione peroxidase 7 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of GPX7 mRNA] Lycopene results in increased expression of GPX7 mRNA |
CTD |
PMID:36216167 |
|
NCBI chr 4:108,257,414...108,263,910
Ensembl chr 4:108,257,587...108,264,158
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G |
Gpx8 |
glutathione peroxidase 8 (putative) |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of GPX8 mRNA Lycopene inhibits the reaction [Atrazine results in decreased expression of GPX8 mRNA] |
CTD |
PMID:36216167 |
|
NCBI chr13:113,179,287...113,182,944
Ensembl chr13:113,179,287...113,182,944
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G |
Gsdmd |
gasdermin D |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSDMD protein] |
CTD |
PMID:36610486 |
|
NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257
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G |
Gsr |
glutathione reductase |
multiple interactions |
EXP |
lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] |
CTD |
PMID:25682699 |
|
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
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G |
Gss |
glutathione synthetase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSS mRNA] |
CTD |
PMID:35917956 PMID:36610486 |
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NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
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G |
Gstp1 |
glutathione S-transferase, pi 1 |
multiple interactions increases expression |
ISO |
[Glucose co-treated with Lycopene] results in increased expression of GSTP1 mRNA Lycopene results in increased expression of GSTP1 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HAVCR1 protein] |
CTD |
PMID:34670089 |
|
NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions decreases response to substance |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein] lycopene results in decreased susceptibility to HMGB1 protein |
CTD |
PMID:22429818 |
|
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA] [lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] |
CTD |
PMID:19071209 |
|
NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
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G |
Hspa4 |
heat shock protein 4 |
multiple interactions |
ISO |
lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] |
CTD |
PMID:23076637 |
|
NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284
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G |
Hspa5 |
heat shock protein 5 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] |
CTD |
PMID:32544411 |
|
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
|
NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression |
ISO |
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased expression of IGF1 mRNA lycopene results in increased expression of IGF1 mRNA |
CTD |
PMID:15084515 PMID:16565789 PMID:16886892 |
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NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
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G |
Igf1r |
insulin-like growth factor I receptor |
decreases expression |
ISO |
lycopene results in decreased expression of IGF1R protein |
CTD |
PMID:17337101 |
|
NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
increases expression |
ISO |
lycopene results in increased expression of IGFBP2 protein |
CTD |
PMID:17337101 |
|
NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO EXP |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] Lycopene inhibits the reaction [Atrazine results in decreased expression of IL10 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL10 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL10] |
CTD |
PMID:25551565 PMID:25682699 PMID:36216167 PMID:36583613 |
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NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
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G |
Il18 |
interleukin 18 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] |
CTD |
PMID:36610486 |
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NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Galactose results in increased expression of IL1B protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL1B] |
CTD |
PMID:25682699 PMID:28974442 PMID:36216167 PMID:36610486 |
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NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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G |
Il2 |
interleukin 2 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Zearalenone results in increased expression of IL2] |
CTD |
PMID:25682699 |
|
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
ISO EXP |
lycopene results in decreased expression of IL6 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL6 protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of IL6] |
CTD |
PMID:15084515 PMID:25682699 PMID:36216167 PMID:36583613 |
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NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
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G |
Irf3 |
interferon regulatory factor 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of IRF3 protein] |
CTD |
PMID:36583613 |
|
NCBI chr 7:44,647,072...44,652,272
Ensembl chr 7:44,647,072...44,652,272
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G |
Irf7 |
interferon regulatory factor 7 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IRF7 mRNA] |
CTD |
PMID:36583613 |
|
NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
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G |
Ivl |
involucrin |
decreases expression |
ISO |
lycopene results in decreased expression of IVL protein |
CTD |
PMID:10769631 |
|
NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042
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G |
Jak1 |
Janus kinase 1 |
increases expression |
ISO |
lycopene results in increased expression of JAK1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
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G |
Jun |
jun proto-oncogene |
decreases expression |
ISO |
lycopene results in decreased expression of JUN mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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G |
Keap1 |
kelch-like ECH-associated protein 1 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of KEAP1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of KEAP1 protein] Lycopene results in increased expression of KEAP1 mRNA |
CTD |
PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
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G |
Kif2a |
kinesin family member 2A |
increases expression |
ISO |
lycopene results in increased expression of KIF2A mRNA |
CTD |
PMID:16886892 |
|
NCBI chr13:107,095,504...107,158,931
Ensembl chr13:107,095,504...107,158,634
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G |
Kpna2 |
karyopherin subunit alpha 2 |
increases expression |
ISO |
lycopene results in increased expression of KPNA2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:106,879,455...106,890,351
Ensembl chr11:106,879,455...106,890,367
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
lycopene results in increased expression of LDLR mRNA |
CTD |
PMID:16886892 |
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NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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G |
Lipa |
lysosomal acid lipase A |
increases expression |
ISO |
lycopene results in increased expression of LIPA mRNA |
CTD |
PMID:16886892 |
|
NCBI chr19:34,469,716...34,504,874
Ensembl chr19:34,469,718...34,504,874
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G |
Lpo |
lactoperoxidase |
multiple interactions |
EXP |
lycopene inhibits the reaction [Diethylnitrosamine results in increased expression of LPO protein] |
CTD |
PMID:24144777 |
|
NCBI chr11:87,697,254...87,716,750
Ensembl chr11:87,697,254...87,719,115
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G |
Lyz1 |
lysozyme 1 |
decreases expression |
EXP |
lycopene results in decreased expression of LYZ1 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr10:117,123,700...117,128,773
Ensembl chr10:117,123,702...117,128,773
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased lipidation of and results in increased localization of MAP1LC3A protein] |
CTD |
PMID:33908429 |
|
NCBI chr 2:155,118,284...155,119,993
Ensembl chr 2:155,118,217...155,119,993
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP ISO |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased localization of MAP1LC3B protein] [Glucose co-treated with Lycopene] results in increased expression of MAP1LC3B mRNA |
CTD |
PMID:36583613 PMID:38444079 |
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NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
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G |
Map2k1 |
mitogen-activated protein kinase kinase 1 |
increases expression |
ISO |
lycopene results in increased expression of MAP2K1 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
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G |
Map2k2 |
mitogen-activated protein kinase kinase 2 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K2 protein |
CTD |
PMID:17337101 |
|
NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
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G |
Map2k4 |
mitogen-activated protein kinase kinase 4 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K4 protein |
CTD |
PMID:17337101 |
|
NCBI chr11:65,579,070...65,679,185
Ensembl chr11:65,579,069...65,679,123
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
decreases expression |
ISO |
lycopene results in decreased expression of MAP2K6 protein |
CTD |
PMID:17337101 |
|
NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
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G |
Mapk1 |
mitogen-activated protein kinase 1 |
multiple interactions increases expression |
ISO EXP |
Lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased phosphorylation of MAPK1 protein]; Lycopene inhibits the reaction [bisphenol A results in decreased expression of MAPK1 protein] Lycopene results in increased expression of MAPK1 protein Lycopene inhibits the reaction [Atrazine results in increased expression of MAPK1 mRNA] |
CTD |
PMID:19551842 PMID:30360616 PMID:32153214 |
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NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
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G |
Mapk14 |
mitogen-activated protein kinase 14 |
decreases expression multiple interactions increases expression |
ISO |
lycopene results in decreased expression of MAPK14 protein Lycopene inhibits the reaction [Oxaliplatin results in increased expression of MAPK14 protein] lycopene results in increased expression of MAPK14 mRNA |
CTD |
PMID:16886892 PMID:17337101 PMID:32544411 |
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NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
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G |
Mapk3 |
mitogen-activated protein kinase 3 |
decreases expression |
ISO |
lycopene results in decreased expression of MAPK3 protein |
CTD |
PMID:17337101 |
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NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
decreases expression |
ISO |
lycopene results in decreased expression of MAPK8 protein |
CTD |
PMID:17337101 |
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NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN1 mRNA] |
CTD |
PMID:33908429 |
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NCBI chr 3:32,583,594...32,633,384
Ensembl chr 3:32,583,614...32,633,388
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of MFN2 protein] |
CTD |
PMID:33908429 |
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NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
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G |
Mgat2 |
mannoside acetylglucosaminyltransferase 2 |
increases expression |
ISO |
lycopene results in increased expression of MGAT2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr12:69,230,932...69,233,547
Ensembl chr12:69,230,931...69,233,544
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G |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of MKI67 protein] |
CTD |
PMID:33592256 |
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NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
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G |
Mlh1 |
mutL homolog 1 |
increases expression |
ISO |
lycopene results in increased expression of MLH1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
EXP |
lycopene inhibits the reaction [Acetaminophen results in increased activity of MMP2 protein] |
CTD |
PMID:27989599 |
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NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
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G |
Msh2 |
mutS homolog 2 |
increases expression |
ISO |
lycopene results in increased expression of MSH2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141
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G |
Msh6 |
mutS homolog 6 |
increases expression |
ISO |
lycopene results in increased expression of MSH6 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr17:88,282,478...88,298,320
Ensembl chr17:88,282,490...88,298,320
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G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
increases expression multiple interactions |
ISO EXP |
lycopene results in increased expression of NFE2L2 mRNA; lycopene results in increased expression of NFE2L2 protein Lycopene inhibits the reaction [Atrazine affects the localization of NFE2L2 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NFE2L2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein] lycopene promotes the reaction [Atrazine results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:19551842 PMID:27102619 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 More...
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NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
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G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased expression of NFKB1 mRNA] |
CTD |
PMID:27102619 |
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NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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G |
Nfkbia |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] |
CTD |
PMID:25551565 |
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NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NLRP3 protein] |
CTD |
PMID:36610486 |
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NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
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G |
Nos1 |
nitric oxide synthase 1, neuronal |
decreases expression |
ISO |
lycopene results in decreased expression of NOS1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
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G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of NQO1 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Lycopene inhibits the reaction [Galactose results in decreased expression of NQO1 mRNA] |
CTD |
PMID:28974442 PMID:30360616 PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Lycopene increases expression of NR1H3 protein in macrophages |
RGD |
PMID:21208793 |
RGD:401842374 |
NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions increases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I2 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NR1I2 protein] Lycopene results in increased expression of NR1I2 mRNA; Lycopene results in increased expression of NR1I2 protein |
CTD |
PMID:36216167 PMID:36403809 |
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NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of NR1I3 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and results in increased localization of NR1I3 protein] |
CTD |
PMID:36216167 PMID:36403809 |
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NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
multiple interactions |
EXP |
[Lycopene co-treated with Atrazine] results in increased expression of NR3C2 mRNA |
CTD |
PMID:36216167 |
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NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NRF1 mRNA] |
CTD |
PMID:33908429 |
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NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
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G |
Ntrk2 |
neurotrophic tyrosine kinase, receptor, type 2 |
increases expression multiple interactions |
ISO |
Lycopene results in increased expression of NTRK2 protein Lycopene inhibits the reaction [bisphenol A results in decreased expression of NTRK2 protein] |
CTD |
PMID:32153214 |
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NCBI chr13:58,954,363...59,281,782
Ensembl chr13:58,954,383...59,281,784
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G |
Nup214 |
nucleoporin 214 |
decreases expression |
ISO |
lycopene results in decreased expression of NUP214 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 2:31,864,446...31,943,204
Ensembl chr 2:31,864,448...31,943,987
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G |
Nup62 |
nucleoporin 62 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NUP62 mRNA] |
CTD |
PMID:35917956 |
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NCBI chr 7:44,465,512...44,481,260
Ensembl chr 7:44,465,512...44,480,236
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of OPA1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of OPA1 protein] |
CTD |
PMID:33908429 |
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NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
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G |
Pah |
phenylalanine hydroxylase |
decreases expression |
EXP |
lycopene results in decreased expression of PAH mRNA |
CTD |
PMID:19555370 |
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NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998
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G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] |
CTD |
PMID:23076637 |
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NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
lycopene inhibits the reaction [[Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PCNA protein] |
CTD |
PMID:19551842 |
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NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
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G |
Pink1 |
PTEN induced putative kinase 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PINK1 protein] |
CTD |
PMID:33908429 PMID:36583613 |
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NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
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G |
Pla2g2a |
phospholipase A2, group IIA (platelets, synovial fluid) |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein] |
CTD |
PMID:22429818 |
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NCBI chr 4:138,559,168...138,562,500
Ensembl chr 4:138,559,171...138,562,497
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G |
Pomc |
pro-opiomelanocortin-alpha |
multiple interactions |
ISO |
lycopene inhibits the reaction [Atrazine results in increased secretion of POMC protein modified form] |
CTD |
PMID:27102619 |
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NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
EXP |
Lycopene affects the reaction [Atrazine affects the expression of PPARA mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of PPARA protein] |
CTD |
PMID:36216167 |
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NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
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G |
Pparg |
peroxisome proliferator activated receptor gamma |
increases expression multiple interactions |
EXP |
Lycopene results in increased expression of PPARG mRNA [Lycopene co-treated with Atrazine] results in increased expression of PPARG mRNA |
CTD |
PMID:36216167 |
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NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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G |
Ppargc1a |
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PPARGC1A mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PPARGC1A protein] |
CTD |
PMID:33908429 |
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NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX1 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019
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G |
Prdx2 |
peroxiredoxin 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRDX2 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
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G |
Prkaa2 |
protein kinase, AMP-activated, alpha 2 catalytic subunit |
increases expression multiple interactions increases phosphorylation |
EXP |
Lycopene results in increased expression of PRKAA2 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAA2 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased phosphorylation of PRKAA2 protein] Lycopene results in increased phosphorylation of PRKAA2 protein |
CTD |
PMID:30360616 |
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NCBI chr 4:104,886,846...104,967,095
Ensembl chr 4:104,887,071...104,967,087
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G |
Prkab1 |
protein kinase, AMP-activated, beta 1 non-catalytic subunit |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of PRKAB1 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr 5:116,151,654...116,162,449
Ensembl chr 5:116,151,645...116,162,567
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G |
Prkab2 |
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of PRKAB2 mRNA] |
CTD |
PMID:30360616 |
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NCBI chr 3:97,565,527...97,581,128
Ensembl chr 3:97,565,509...97,581,128
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G |
Prkag2 |
protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
multiple interactions |
EXP |
Lycopene affects the reaction [Atrazine results in increased expression of PRKAG2 mRNA] |
CTD |
PMID:30360616 |
|
NCBI chr 5:25,067,733...25,311,576
Ensembl chr 5:25,067,742...25,305,640
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G |
Prkdc |
protein kinase, DNA activated, catalytic polypeptide |
decreases expression |
ISO |
lycopene results in decreased expression of PRKDC mRNA |
CTD |
PMID:16886892 |
|
NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PRKN protein] |
CTD |
PMID:36583613 |
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NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of PTGS2 mRNA]; Lycopene inhibits the reaction [Galactose results in increased expression of PTGS2 mRNA] |
CTD |
PMID:28974442 PMID:36216167 |
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NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PYCARD protein] |
CTD |
PMID:36610486 |
|
NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
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G |
Rad50 |
RAD50 double strand break repair protein |
increases expression |
ISO |
lycopene results in increased expression of RAD50 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
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G |
Rassf7 |
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
increases expression |
ISO |
lycopene results in increased expression of RASSF7 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 7:140,795,338...140,798,571
Ensembl chr 7:140,795,773...140,798,571
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G |
Rb1 |
RB transcriptional corepressor 1 |
multiple interactions decreases phosphorylation |
ISO |
lycopene inhibits the reaction [Genistein results in increased phosphorylation of and results in decreased activity of RB1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] lycopene results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16565789 PMID:17051425 PMID:17337101 |
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NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
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G |
Rdx |
radixin |
decreases expression |
ISO |
lycopene results in decreased expression of RDX mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 9:51,958,450...52,000,038
Ensembl chr 9:51,958,473...52,011,763
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G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of RELA protein] |
CTD |
PMID:36583613 |
|
NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
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G |
Ripk1 |
receptor (TNFRSF)-interacting serine-threonine kinase 1 |
multiple interactions |
ISO |
[Glucose co-treated with Lycopene] results in increased expression of RIPK1 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
multiple interactions |
ISO |
[Glucose co-treated with Lycopene] results in increased expression of RIPK3 mRNA |
CTD |
PMID:38444079 |
|
NCBI chr14:56,022,452...56,026,314
Ensembl chr14:56,022,452...56,026,322
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G |
Rps6ka1 |
ribosomal protein S6 kinase polypeptide 1 |
decreases expression |
ISO |
lycopene results in decreased expression of RPS6KA1 protein |
CTD |
PMID:17337101 |
|
NCBI chr 4:133,574,601...133,615,466
Ensembl chr 4:133,574,601...133,615,108
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G |
Rps6ka3 |
ribosomal protein S6 kinase polypeptide 3 |
decreases expression |
ISO |
lycopene results in decreased expression of RPS6KA3 protein |
CTD |
PMID:17337101 |
|
NCBI chr X:158,038,652...158,151,240
Ensembl chr X:157,993,303...158,151,240
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G |
Rrm2 |
ribonucleotide reductase M2 |
increases expression |
ISO |
lycopene results in increased expression of RRM2 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
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G |
Sbp |
spermine binding protein |
decreases expression |
ISO |
lycopene results in decreased expression of SBP mRNA |
CTD |
PMID:15084515 |
|
NCBI chr17:24,141,525...24,164,577
Ensembl chr17:24,160,646...24,164,581
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G |
Sele |
selectin, endothelial cell |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA] |
CTD |
PMID:22429818 PMID:25551565 |
|
NCBI chr 1:163,867,200...163,886,056
Ensembl chr 1:163,875,773...163,885,246
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G |
Selenop |
selenoprotein P |
decreases expression |
ISO |
lycopene results in decreased expression of SELENOP mRNA |
CTD |
PMID:16886892 |
|
NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990
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G |
Selenos |
selenoprotein S |
increases expression |
ISO |
Lycopene results in increased expression of SELENOS mRNA |
CTD |
PMID:38444079 |
|
NCBI chr 7:65,729,397...65,739,153
Ensembl chr 7:65,729,397...65,739,153
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO EXP |
lycopene inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein] Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT1 protein] |
CTD |
PMID:28974442 PMID:33908429 |
|
NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
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G |
Sirt3 |
sirtuin 3 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SIRT3 protein] |
CTD |
PMID:33908429 |
|
NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222
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G |
Skap2 |
src family associated phosphoprotein 2 |
decreases expression |
EXP |
lycopene results in decreased expression of SKAP2 mRNA |
CTD |
PMID:19555370 |
|
NCBI chr 6:51,836,145...51,989,529
Ensembl chr 6:51,834,402...51,989,529
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G |
Smad3 |
SMAD family member 3 |
increases expression |
ISO |
lycopene results in increased expression of SMAD3 mRNA |
CTD |
PMID:16886892 |
|
NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
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G |
Smc1a |
structural maintenance of chromosomes 1A |
decreases expression |
ISO |
lycopene results in decreased expression of SMC1A mRNA |
CTD |
PMID:16886892 |
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NCBI chr X:150,799,386...150,844,969
Ensembl chr X:150,799,424...150,845,690
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G |
Sod1 |
superoxide dismutase 1, soluble |
increases expression multiple interactions |
EXP ISO |
Lycopene results in increased expression of SOD1 mRNA [Glucose co-treated with Lycopene] results in increased expression of SOD1 mRNA Lycopene inhibits the reaction [Atrazine results in increased expression of SOD1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD1 mRNA]; Lycopene promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 protein] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 |
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NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
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G |
Sod2 |
superoxide dismutase 2, mitochondrial |
multiple interactions increases expression |
EXP ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD2 protein] Lycopene results in increased expression of SOD2 mRNA [Glucose co-treated with Lycopene] results in increased expression of SOD2 mRNA |
CTD |
PMID:33908429 PMID:35917956 PMID:36216167 PMID:36610486 PMID:38444079 |
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NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
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G |
Sod3 |
superoxide dismutase 3, extracellular |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of SOD3 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SOD3 mRNA] |
CTD |
PMID:35917956 PMID:36216167 PMID:36610486 |
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NCBI chr 5:52,521,146...52,527,080
Ensembl chr 5:52,521,133...52,528,760
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
EXP ISO |
Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA alternative form]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of SQSTM1 protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of SQSTM1 protein] [Glucose co-treated with Lycopene] results in increased expression of SQSTM1 mRNA |
CTD |
PMID:30360616 PMID:36583613 PMID:38444079 |
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NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
decreases expression |
ISO |
lycopene results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:15084515 |
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NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions |
ISO |
lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of STAR protein]; lycopene inhibits the reaction [decamethrin results in decreased expression of STAR mRNA] |
CTD |
PMID:19071209 PMID:23076637 |
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NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases expression |
ISO |
lycopene results in increased expression of STAT3 mRNA |
CTD |
PMID:16886892 |
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NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
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G |
Sting1 |
stimulator of interferon response cGAMP interactor 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of STING1 protein] |
CTD |
PMID:36583613 |
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NCBI chr18:35,866,731...35,873,607
Ensembl chr18:35,866,732...35,873,607
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G |
Tbk1 |
TANK-binding kinase 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased phosphorylation of TBK1 protein] |
CTD |
PMID:36583613 |
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NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TFAM mRNA] |
CTD |
PMID:33908429 |
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NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
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G |
Tff1 |
trefoil factor 1 |
decreases expression |
ISO |
lycopene results in decreased expression of TFF1 mRNA |
CTD |
PMID:16886892 |
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NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
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G |
Tfpi2 |
tissue factor pathway inhibitor 2 |
decreases expression |
ISO |
lycopene results in decreased expression of TFPI2 mRNA |
CTD |
PMID:16886892 |
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NCBI chr 6:3,962,589...3,988,977
Ensembl chr 6:3,962,595...3,988,919
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G |
Tgfa |
transforming growth factor alpha |
increases expression |
ISO |
lycopene results in increased expression of TGFA mRNA |
CTD |
PMID:16886892 |
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NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
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G |
Tlr2 |
toll-like receptor 2 |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR2 protein] |
CTD |
PMID:22429818 |
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NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO EXP |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] Lycopene affects the reaction [Atrazine affects the expression of TLR4 mRNA] |
CTD |
PMID:22429818 PMID:36216167 |
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NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
[Lycopene co-treated with Diethylnitrosamine] results in increased expression of TNF mRNA; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of TNF protein] Lycopene inhibits the reaction [Atrazine results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TNF protein]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TNF protein]; Lycopene inhibits the reaction [Galactose results in increased expression of TNF protein]; Lycopene inhibits the reaction [Zearalenone results in increased expression of TNF] [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of TNF mRNA]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein] |
CTD |
PMID:19551842 PMID:22429818 PMID:25551565 PMID:25682699 PMID:28974442 PMID:32544411 PMID:36216167 PMID:36583613 More...
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NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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G |
Traf6 |
TNF receptor-associated factor 6 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of TRAF6 protein] |
CTD |
PMID:36216167 |
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NCBI chr 2:101,508,765...101,532,013
Ensembl chr 2:101,508,774...101,532,014
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G |
Trp53 |
transformation related protein 53 |
decreases expression multiple interactions |
ISO EXP |
lycopene results in decreased expression of TP53 mRNA Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of TP53 mRNA] |
CTD |
PMID:16886892 PMID:36583613 |
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NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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G |
Tshb |
thyroid stimulating hormone, beta subunit |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of TSHB protein] |
CTD |
PMID:33592256 |
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NCBI chr 3:102,684,621...102,718,175
Ensembl chr 3:102,682,781...102,690,034
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
EXP |
Lycopene affects the reaction [Atrazine affects the expression of TXN1 mRNA] |
CTD |
PMID:36216167 |
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NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
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G |
Txn2 |
thioredoxin 2 |
multiple interactions decreases expression |
EXP |
Lycopene inhibits the reaction [Atrazine results in decreased expression of TXN2 mRNA] Lycopene results in decreased expression of TXN2 mRNA |
CTD |
PMID:36216167 |
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NCBI chr15:77,799,251...77,813,194
Ensembl chr15:77,799,247...77,813,206
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:22429818 |
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NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
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G |
Vcp |
valosin containing protein |
increases expression |
ISO |
lycopene results in increased expression of VCP mRNA |
CTD |
PMID:16886892 |
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NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of VEGFA protein] |
CTD |
PMID:33592256 |
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NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
EXP |
Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 mRNA]; Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of XBP1 protein] |
CTD |
PMID:36583613 |
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NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
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