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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:elemental mercury
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Accession:CHEBI:35113 term browser browse the term



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Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein affects expression ISO Mercury affects the expression of A1BG protein CTD PMID:22030286 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
JBrowse link
G A2m alpha-2-macroglobulin decreases expression ISO Mercury results in decreased expression of A2M mRNA CTD PMID:17547211 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 affects expression ISO Mercury affects the expression of ABCA1 mRNA CTD PMID:23920476 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [ABCB1 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury; ABCB1 gene SNP affects the susceptibility to and affects the abundance of Mercury CTD PMID:27262785 PMID:32946573 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP Mercury results in increased expression of ABCB1B mRNA CTD PMID:12730625 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression
multiple interactions
EXP
ISO
Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein
ABCC1 gene SNP affects the susceptibility to and affects the abundance of Mercury
CTD PMID:12730625 PMID:27262785 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
affects response to substance
increases export
increases transport
affects transport
ISO
EXP
ABCC2 gene SNP affects the susceptibility to and affects the abundance of Mercury; ABCC2 protein affects the transport of [Mercury co-treated with Cysteine]; Adenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]
ABCC2 gene mutant form affects the susceptibility to Mercury
ABCC2 protein results in increased export of Mercury
ABCC2 protein affects the transport of Mercury
EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of ABCC2 protein]; Mercury results in increased expression of and affects the localization of ABCC2 protein
CTD PMID:21134393 PMID:23052037 PMID:23059061 PMID:24039982 PMID:25145654 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Mercury results in increased expression of ABCG1 mRNA CTD PMID:16823088 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Mercury results in increased expression of ABCG2 mRNA CTD PMID:17547211 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Mercury results in increased expression of ABL1 mRNA CTD PMID:19937285 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Ache acetylcholinesterase increases activity
multiple interactions
ISO
EXP
Mercury results in increased activity of ACHE protein
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium co-treated with Zinc] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased activity of ACHE protein
CTD PMID:10798623 PMID:37415728 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO Mercury results in decreased expression of ACP2 mRNA CTD PMID:17547211 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Mercury results in decreased expression of ACSL1 mRNA CTD PMID:17547211 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Actb actin, beta increases expression EXP Mercury results in increased expression of ACTB mRNA CTD PMID:22688007 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Adck5 aarF domain containing kinase 5 decreases expression ISO Mercury analog results in decreased expression of ADCK5 mRNA CTD PMID:25056781 NCBI chr 7:108,301,623...108,319,439
Ensembl chr 7:108,301,415...108,319,436
JBrowse link
G Adm adrenomedullin increases expression ISO Mercury results in increased expression of ADM mRNA CTD PMID:17547211 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Mercury results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:16093525 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases expression ISO Mercury results in decreased expression of AKR1B1 mRNA CTD PMID:17547211 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 multiple interactions EXP [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of AKR7A3 protein CTD PMID:29298499 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1s1 AKT1 substrate 1 decreases expression ISO Mercury results in decreased expression of AKT1S1 mRNA CTD PMID:22008530 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression ISO Mercury results in decreased expression of AKT2 mRNA CTD PMID:16823088 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions
decreases activity
affects abundance
ISO [zinc chloride inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]] which affects the abundance of Mercury; Sodium Selenite inhibits the reaction [Mercury results in decreased activity of ALAD protein]
ALAD gene polymorphism affects the abundance of Mercury
CTD PMID:12499120 PMID:14615064 PMID:25728017 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Alb albumin increases export
multiple interactions
ISO
EXP
Mercury results in increased export of ALB protein
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; [Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of ALB protein; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]
CTD PMID:30090589 PMID:37137463 PMID:37676925 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression ISO Mercury analog results in decreased expression of ALDH5A1 mRNA CTD PMID:25056781 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Mercury results in decreased expression of ALDH6A1 mRNA CTD PMID:17547211 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase increases expression ISO Mercury results in increased expression of ALG3 mRNA CTD PMID:16823088 NCBI chr11:80,300,487...80,306,014
Ensembl chr11:80,300,498...80,307,912
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 increases expression ISO Mercury results in increased expression of ALS2 mRNA CTD PMID:19937285 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
JBrowse link
G Ank1 ankyrin 1 decreases expression ISO Mercury results in decreased expression of ANK1 mRNA CTD PMID:19937285 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759
JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 increases expression ISO Mercury results in increased expression of ANKHD1 mRNA CTD PMID:16823088 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024
JBrowse link
G Anxa2 annexin A2 increases expression ISO Mercury results in increased expression of ANXA2 mRNA CTD PMID:17547211 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 decreases expression ISO Mercury results in decreased expression of AP2A2 mRNA CTD PMID:19937285 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO Mercury affects the expression of APOA2 protein CTD PMID:22030286 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE gene polymorphism affects the susceptibility to Mercury; APOE polymorphism affects the susceptibility to Mercury CTD PMID:12897404 PMID:23603214 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases secretion
ISO Estradiol inhibits the reaction [Mercury results in increased secretion of APP protein modified form]
Mercury results in increased secretion of APP protein alternative form; Mercury results in increased secretion of APP protein modified form
CTD PMID:12182891 PMID:25673500 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases activity
EXP
ISO
Mercury inhibits the reaction [AQP1 protein results in increased transport of Water]
Mercaptoethanol inhibits the reaction [Mercury results in decreased activity of AQP1 protein]
CTD PMID:21259319 PMID:24028651 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp10 aquaporin 10 decreases activity
affects activity
ISO Mercury results in decreased activity of AQP10 protein
Mercury affects the activity of AQP10 protein
CTD PMID:11573934 PMID:12084581 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815
JBrowse link
G Aqp8 aquaporin 8 multiple interactions EXP Mercury affects the reaction [AQP8 protein affects the transport of Water] CTD PMID:18059526 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Aqp9 aquaporin 9 multiple interactions EXP Mercury inhibits the reaction [AQP9 protein results in increased transport of Water] CTD PMID:21259319 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Arf4 ARF GTPase 4 decreases expression ISO Mercury results in decreased expression of ARF4 mRNA CTD PMID:16823088 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
JBrowse link
G Arg1 arginase 1 decreases activity EXP Mercury results in decreased activity of ARG1 protein CTD PMID:11916150 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arg2 arginase 2 decreases activity EXP Mercury results in decreased activity of ARG2 protein CTD PMID:11916150 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgef28 Rho guanine nucleotide exchange factor 28 decreases expression ISO Mercury results in decreased expression of ARHGEF28 mRNA CTD PMID:19937285 NCBI chr 2:29,263,888...29,560,595
Ensembl chr 2:29,263,886...29,560,672
JBrowse link
G Arid1a AT-rich interaction domain 1A increases expression ISO Mercury results in increased expression of ARID1A mRNA CTD PMID:19937285 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arid4a AT-rich interaction domain 4A affects expression ISO Mercury affects the expression of ARID4A mRNA CTD PMID:23920476 NCBI chr 6:89,522,459...89,593,868
Ensembl chr 6:89,522,442...89,593,510
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Mercury results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:16093525 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Mercury results in increased expression of ATP1B3 mRNA CTD PMID:22688007 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A decreases expression ISO Mercury results in decreased expression of ATP6V1A mRNA CTD PMID:16823088 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Mercury analog results in decreased expression of ATXN3 mRNA CTD PMID:25056781 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Atxn7l3 ataxin 7-like 3 decreases expression ISO Mercury analog results in decreased expression of ATXN7L3 mRNA CTD PMID:25056781 NCBI chr10:87,242,843...87,250,186
Ensembl chr10:87,243,587...87,250,620
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Mercury results in decreased expression of AZGP1 mRNA CTD PMID:17547211 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G B2m beta-2 microglobulin multiple interactions ISO [Metals, Heavy results in increased abundance of Mercury] which results in increased secretion of B2M protein CTD PMID:39357351 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO Mercury results in decreased expression of BAD mRNA CTD PMID:19937285 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag6 BAG cochaperone 6 decreases expression ISO Mercury results in decreased expression of BAG6 mRNA CTD PMID:16823088 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bank1 B-cell scaffold protein with ankyrin repeats 1 increases expression ISO Mercury results in increased expression of BANK1 mRNA CTD PMID:16823088 NCBI chr 2:224,530,475...224,800,420
Ensembl chr 2:224,530,475...224,800,405
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
Mercury results in increased expression of BAX protein
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein; Luteolin affects the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein]
CTD PMID:21186712 PMID:29115570 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Mercury results in decreased expression of BCL2 protein CTD PMID:21186712 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l11 Bcl2-like 11 decreases expression ISO Mercury results in decreased expression of BCL2L11 mRNA CTD PMID:19937285 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcor BCL6 co-repressor increases expression ISO Mercury results in increased expression of BCOR mRNA CTD PMID:16823088 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
affects response to substance
ISO Mercury results in decreased expression of BDNF mRNA
BDNF polymorphism affects the susceptibility to Mercury
CTD PMID:16301096 PMID:19937285 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Mercury results in increased expression of BHLHE40 mRNA CTD PMID:17547211 PMID:19937285 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Mercury results in increased expression of BIRC3 mRNA CTD PMID:16823088 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression ISO Mercury results in increased expression of BMPR2 mRNA CTD PMID:19937285 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase increases expression ISO Mercury results in increased expression of BRAF mRNA CTD PMID:19937285 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO Mercury results in increased expression of BUB1 mRNA CTD PMID:16823088 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO Mercury results in decreased expression of BUB3 mRNA CTD PMID:16823088 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036
JBrowse link
G C3 complement C3 affects expression ISO Mercury affects the expression of C3 protein CTD PMID:22030286 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C6 complement C6 affects expression ISO Mercury affects the expression of C6 protein CTD PMID:22030286 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO Mercury results in decreased expression of CADM1 mRNA CTD PMID:19937285 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Cadm2 cell adhesion molecule 2 decreases expression ISO Mercury analog results in decreased expression of CADM2 mRNA CTD PMID:25056781 NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Mercury results in decreased expression of CALM3 mRNA CTD PMID:16823088 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO Mercury analog results in decreased expression of CAPNS1 mRNA CTD PMID:25056781 NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta increases expression ISO Mercury results in increased expression of CAPZB mRNA CTD PMID:19937285 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Mercury results in decreased activity of CA1 protein CTD PMID:18237030 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Mercury results in decreased activity of CA2 protein CTD PMID:18237030 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car3 carbonic anhydrase 3 increases expression ISO Mercury results in increased expression of CA3 mRNA CTD PMID:16823088 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Carns1 carnosine synthase 1 decreases expression ISO Mercury analog results in decreased expression of CARNS1 mRNA CTD PMID:25056781 NCBI chr 1:201,459,061...201,470,019
Ensembl chr 1:201,459,076...201,469,845
JBrowse link
G Casp1 caspase 1 multiple interactions ISO CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA] CTD PMID:28453771 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions
ISO
EXP
Mercury results in increased activity of CASP3 protein
Mercury results in increased expression of CASP3 protein
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of CASP3 protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP3 protein]
CTD PMID:16823075 PMID:21186712 PMID:29115570 PMID:37415728 PMID:37676925 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
EXP
ISO
Mercury results in increased expression of CASP9 protein
[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of CASP9 protein]
CTD PMID:21186712 PMID:29115570 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Mercury results in decreased activity of CAT protein
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased activity of CAT protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased activity of CAT protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased activity of CAT protein; [Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of CAT protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; Selenium affects the reaction [Mercury results in decreased activity of CAT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]
CTD PMID:17176674 PMID:20143455 PMID:37415728 PMID:37676925 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Catsper2 cation channel, sperm associated 2 decreases expression ISO Mercury results in decreased expression of CATSPER2 mRNA CTD PMID:29549816 NCBI chr 3:108,368,654...108,389,380
Ensembl chr 3:108,368,668...108,388,050
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression ISO Mercury analog results in decreased expression of CAVIN2 mRNA CTD PMID:25056781 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Cbx7 chromobox 7 decreases expression ISO Mercury analog results in decreased expression of CBX7 mRNA CTD PMID:25056781 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression ISO Mercury results in increased expression of CCL12 mRNA CTD PMID:30103553 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
EXP
ISO
Mercury results in increased expression of CCL3 mRNA
MT3 protein affects the reaction [Mercury results in increased expression of CCL3 mRNA]
CTD PMID:12730625 PMID:30103553 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 multiple interactions ISO [MT3 protein affects the susceptibility to Mercury] which affects the expression of CCL7 mRNA CTD PMID:30103553 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Mercury results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression ISO Mercury results in decreased expression of CCR2 mRNA CTD PMID:16823088 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd226 CD226 molecule increases expression ISO Mercury results in increased expression of CD226 mRNA CTD PMID:16823088 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Cd40 CD40 molecule increases expression ISO Mercury results in increased expression of CD40 mRNA CTD PMID:16823088 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd84 CD84 molecule decreases expression ISO Mercury results in decreased expression of CD84 mRNA CTD PMID:16823088 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Mercury results in decreased expression of CDH1 mRNA CTD PMID:26600472 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Mercury results in increased expression of CDK5R1 mRNA CTD PMID:16823088 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdkl2 cyclin dependent kinase like 2 decreases expression ISO Mercury analog results in decreased expression of CDKL2 mRNA CTD PMID:25056781 NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Mercury results in increased expression of CDKN3 mRNA CTD PMID:17547211 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO Mercury results in decreased expression of CEBPD mRNA CTD PMID:19937285 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cfb complement factor B decreases expression
affects expression
ISO Mercury results in decreased expression of CFB mRNA
Mercury affects the expression of CFB protein
CTD PMID:17547211 PMID:22030286 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Cfd complement factor D increases expression ISO Mercury results in increased expression of CFD mRNA CTD PMID:16823088 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Mercury analog results in decreased expression of CHAC1 mRNA CTD PMID:25056781 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Mercury results in decreased expression of CHAT mRNA CTD PMID:7781173 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Cideb cell death-inducing DFFA-like effector b decreases expression ISO Mercury results in decreased expression of CIDEB mRNA CTD PMID:17547211 NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Mercury results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 increases expression ISO Mercury results in increased expression of CLASP2 mRNA CTD PMID:16823088 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Clgn calmegin decreases expression ISO Mercury results in decreased expression of CLGN mRNA CTD PMID:17547211 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
JBrowse link
G Clk1 CDC-like kinase 1 affects expression ISO Mercury affects the expression of CLK1 mRNA CTD PMID:16823088 NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression
increases expression
ISO Mercury results in decreased expression of CLPTM1 mRNA
Mercury results in increased expression of CLPTM1 mRNA
CTD PMID:16823088 PMID:17547211 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Cltc clathrin heavy chain decreases expression ISO Mercury results in decreased expression of CLTC mRNA CTD PMID:16823088 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog decreases expression ISO Mercury analog results in decreased expression of CMBL mRNA CTD PMID:25056781 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 increases expression ISO Mercury results in increased expression of CNOT3 mRNA CTD PMID:19937285 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167
JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain decreases methylation ISO Mercury results in decreased methylation of COL26A1 gene CTD PMID:25748564 NCBI chr12:19,792,693...19,938,556
Ensembl chr12:19,792,728...19,938,556
JBrowse link
G Col4a3 collagen type IV alpha 3 chain increases expression ISO Mercury results in increased expression of COL4A3 mRNA CTD PMID:16823088 NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
JBrowse link
G Comt catechol-O-methyltransferase affects response to substance ISO COMT gene polymorphism affects the susceptibility to Mercury; COMT gene SNP affects the susceptibility to Mercury CTD PMID:19296409 PMID:24593143 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cp ceruloplasmin affects expression ISO Mercury affects the expression of CP protein CTD PMID:22030286 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpn2 carboxypeptidase N subunit 2 affects expression ISO Mercury affects the expression of CPN2 protein CTD PMID:22030286 NCBI chr11:70,486,054...70,495,937
Ensembl chr11:70,486,057...70,496,472
JBrowse link
G Cpox coproporphyrinogen oxidase affects response to substance
multiple interactions
decreases activity
ISO CPOX polymorphism affects the susceptibility to Mercury; CPOX protein affects the susceptibility to Mercury; CPOX protein polymorphism affects the susceptibility to Mercury
[Mercury results in decreased activity of CPOX protein] which results in increased abundance of Coproporphyrins; Mercury inhibits the reaction [CPOX protein results in decreased carboxylation of coproporphyrinogen III]; Mercury inhibits the reaction [CPOX protein results in increased chemical synthesis of protoporphyrinogen]
CTD PMID:16214298 PMID:16343843 PMID:19339664 NCBI chr11:41,936,585...41,946,568
Ensembl chr11:41,936,591...41,946,746
JBrowse link
G Cpz carboxypeptidase Z increases expression ISO Mercury results in increased expression of CPZ mRNA CTD PMID:16823088 NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
JBrowse link
G Crip1 cysteine rich protein 1 decreases expression ISO Mercury analog results in decreased expression of CRIP1 mRNA CTD PMID:25056781 NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620
JBrowse link
G Cryaa crystallin, alpha A decreases expression ISO Mercury results in decreased expression of CRYAA mRNA CTD PMID:17547211 NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
JBrowse link
G Cryab crystallin, alpha B multiple interactions
decreases response to substance
increases expression
ISO [arsenite co-treated with Cadmium] promotes the reaction [Mercury results in increased expression of CRYAB protein]; [arsenite co-treated with Mercury] promotes the reaction [Cadmium results in increased expression of CRYAB protein]; [Mercury co-treated with Cadmium] promotes the reaction [arsenite results in increased expression of CRYAB protein]
CRYAB protein results in decreased susceptibility to Mercury
CTD PMID:15590893 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cryz crystallin zeta multiple interactions
increases activity
ISO Mercury promotes the reaction [Benzo(a)pyrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CRYZ protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CRYZ mRNA]
Mercury results in increased activity of CRYZ protein
CTD PMID:15297030 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression ISO Mercury results in increased expression of CSPG5 mRNA CTD PMID:16823088 NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758
JBrowse link
G Csrnp2 cysteine and serine rich nuclear protein 2 increases expression ISO Mercury results in increased expression of CSRNP2 mRNA CTD PMID:19937285 NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075
JBrowse link
G Cst3 cystatin C multiple interactions ISO [Metals, Heavy results in increased abundance of Mercury] which results in increased secretion of CST3 protein CTD PMID:39357351 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Mercury results in increased expression of CTBP1 mRNA CTD PMID:16823088 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Ctsb cathepsin B increases activity ISO Mercury results in increased activity of CTSB protein CTD PMID:25237059 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cul4b cullin 4B decreases expression ISO Mercury analog results in decreased expression of CUL4B mRNA CTD PMID:25056781 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cyb561 cytochrome b-561 decreases expression ISO Mercury results in decreased expression of CYB561 mRNA CTD PMID:16823088 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases stability
increases activity
increases expression
ISO [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Buthionine Sulfoximine promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Cycloheximide promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A1 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrazolanthrone promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; U 0126 inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; U 0126 promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]
Mercury results in increased stability of CYP1A1 protein
Mercury results in increased activity of CYP1A1 protein
CTD PMID:15297030 PMID:16093525 PMID:18078826 PMID:22579925 PMID:23231920 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases activity
ISO [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
Mercury results in increased activity of CYP1A2 protein
CTD PMID:22579925 PMID:23231920 PMID:36245390 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]
Mercury results in increased expression of CYP1B1 protein
CTD PMID:22579925 PMID:23231920 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 increases expression ISO Mercury results in increased expression of CYP2U1 mRNA CTD PMID:16823088 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases activity EXP Mercury results in decreased activity of CYP7A1 protein CTD PMID:1175606 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dab1 DAB adaptor protein 1 increases expression ISO Mercury results in increased expression of DAB1 mRNA CTD PMID:16823088 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552
JBrowse link
G Dcx doublecortin multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of DCX mRNA CTD PMID:37914285 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Def8 differentially expressed in FDCP 8 homolog decreases expression ISO Mercury results in decreased expression of DEF8 mRNA CTD PMID:22008530 NCBI chr19:51,474,783...51,495,638
Ensembl chr19:51,474,878...51,495,638
JBrowse link
G Diras1 DIRAS family GTPase 1 decreases expression ISO Mercury results in decreased expression of DIRAS1 mRNA CTD PMID:19937285 NCBI chr 7:8,687,964...8,692,828
Ensembl chr 7:8,687,942...8,693,831
JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 decreases expression ISO Mercury results in decreased expression of DNAH1 mRNA CTD PMID:16823088 NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350
JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 increases expression EXP Mercury results in increased expression of DNAJA2 mRNA CTD PMID:22688007 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
JBrowse link
G Dock10 dedicator of cytokinesis 10 increases expression ISO Mercury results in increased expression of DOCK10 mRNA CTD PMID:16823088 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Mercury results in increased expression of DPYSL4 mRNA CTD PMID:16823088 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP Mercury inhibits the reaction [3-N-methylspiperone binds to DRD3 protein] CTD PMID:10215675 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 multiple interactions EXP Mercury inhibits the reaction [3-N-methylspiperone binds to DRD4 protein] CTD PMID:10215675 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dtna dystrobrevin, alpha increases expression ISO Mercury results in increased expression of DTNA mRNA CTD PMID:16823088 NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261
JBrowse link
G Eea1 early endosome antigen 1 increases expression ISO Mercury results in increased expression of EEA1 mRNA CTD PMID:16823088 NCBI chr 7:30,554,686...30,722,186
Ensembl chr 7:30,554,552...30,718,487
JBrowse link
G Efnb1 ephrin B1 increases expression ISO Mercury results in increased expression of EFNB1 mRNA CTD PMID:16823088 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 decreases activity
multiple interactions
ISO Mercury results in decreased activity of EIF2AK1 protein
Nitric Oxide inhibits the reaction [Mercury results in decreased activity of EIF2AK1 protein]
CTD PMID:17689536 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573
JBrowse link
G Eif3f eukaryotic translation initiation factor 3, subunit F decreases expression ISO Mercury results in decreased expression of EIF3F mRNA CTD PMID:16823088 NCBI chr 1:162,934,220...162,943,204
Ensembl chr 1:162,934,212...162,943,204
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 decreases expression ISO Mercury analog results in decreased expression of EIF4G1 mRNA CTD PMID:25056781 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO Mercury results in decreased expression of ELP1 mRNA CTD PMID:16823088 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Emx2 empty spiracles homeobox 2 increases expression ISO Mercury results in increased expression of EMX2 mRNA CTD PMID:16823088 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594
JBrowse link
G En1 engrailed homeobox 1 increases expression ISO Mercury results in increased expression of EN1 mRNA CTD PMID:16823088 NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 increases expression ISO Mercury results in increased expression of ENPP1 mRNA CTD PMID:17547211 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein affects the reaction [Mercury affects the localization of SLC22A8 protein]; EPO protein inhibits the reaction [Mercury results in increased expression of SLC22A19 protein]; EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of ABCC2 protein]; EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of SLC22A6 protein]; EPO protein promotes the reaction [Mercury results in increased expression of SLC22A8 protein] CTD PMID:32909846 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Esr2 estrogen receptor 2 increases expression ISO Mercury results in increased expression of ESR2 mRNA CTD PMID:16823088 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Etfb electron transfer flavoprotein subunit beta increases expression ISO Mercury results in increased expression of ETFB mRNA CTD PMID:16823088 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Mercury results in increased expression of ETS2 mRNA CTD PMID:17547211 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Mercury results in increased expression of EZH1 mRNA CTD PMID:16823088 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G F10 coagulation factor X decreases expression ISO Mercury results in decreased expression of F10 mRNA CTD PMID:17547211 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F5 coagulation factor V decreases expression ISO Mercury results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression EXP Mercury results in increased expression of FABP5 mRNA CTD PMID:12730625 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fabp7 fatty acid binding protein 7 increases expression ISO Mercury results in increased expression of FABP7 mRNA CTD PMID:16823088 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression ISO Mercury analog results in decreased expression of FAM184B mRNA CTD PMID:25056781 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mercury inhibits the reaction [FAS protein binds to FAS protein] CTD PMID:16039944 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fcer1g Fc epsilon receptor Ig affects response to substance ISO FCER1G protein affects the susceptibility to Mercury CTD PMID:20976163 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA] CTD PMID:28453771 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr3a Fc gamma receptor 3A decreases expression ISO Mercury results in decreased expression of FCGR3A mRNA CTD PMID:16823088 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fcrla Fc receptor-like A decreases expression ISO Mercury results in decreased expression of FCRLA mRNA CTD PMID:16823088 NCBI chr13:83,160,453...83,170,170
Ensembl chr13:83,160,398...83,170,762
JBrowse link
G Fech ferrochelatase decreases activity ISO Mercury results in decreased activity of FECH protein CTD PMID:2347080 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Ferd3l Fer3-like bHLH transcription factor decreases expression ISO Mercury results in decreased expression of FERD3L mRNA CTD PMID:19937285 NCBI chr 6:50,645,379...50,646,268
Ensembl chr 6:50,645,379...50,646,268
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO Mercury results in increased expression of FGF2 mRNA CTD PMID:16823088 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Flnb filamin B increases expression ISO Mercury results in increased expression of FLNB mRNA CTD PMID:19937285 NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Mercury results in decreased expression of FN1 mRNA CTD PMID:16823088 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Mercury promotes the reaction [HSPA5 protein binds to FOS enhancer] CTD PMID:15111246 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Mercury results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxi1 forkhead box I1 decreases expression ISO Mercury results in decreased expression of FOXI1 mRNA CTD PMID:19937285 NCBI chr10:18,806,292...18,810,231
Ensembl chr10:18,806,308...18,810,231
JBrowse link
G Foxk1 forkhead box K1 increases expression ISO Mercury results in increased expression of FOXK1 mRNA CTD PMID:19937285 NCBI chr12:12,110,119...12,175,089
Ensembl chr12:12,115,950...12,175,089
JBrowse link
G Frmd6 FERM domain containing 6 decreases expression ISO Mercury analog results in decreased expression of FRMD6 mRNA CTD PMID:25056781 NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:89,346,035...89,419,579
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Mercury results in decreased expression of FURIN mRNA CTD PMID:17547211 NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Mercury results in decreased activity of G6PD protein CTD PMID:10798623 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 increases expression ISO Mercury results in increased expression of GABRA6 mRNA CTD PMID:16823088 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Mercury results in increased expression of GAS7 mRNA CTD PMID:16823088 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276
JBrowse link
G Gatad2b GATA zinc finger domain containing 2B decreases expression ISO Mercury analog results in decreased expression of GATAD2B mRNA CTD PMID:25056781 NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
affects response to substance
multiple interactions
ISO
EXP
Mercury results in increased expression of GCLC mRNA
GCLC gene SNP affects the susceptibility to Mercury
[Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GCLC protein; GCLC gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury]
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein]
CTD PMID:17547211 PMID:19515364 PMID:22236634 PMID:27837179 PMID:30359721 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression
affects abundance
affects metabolic processing
ISO Mercury results in decreased expression of GCLM mRNA
GCLM gene polymorphism affects the abundance of Mercury; GCLM protein affects the abundance of Mercury
GCLM polymorphism affects the metabolism of Mercury
CTD PMID:16961004 PMID:18560528 PMID:19937285 PMID:21925580 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Ggcx gamma-glutamyl carboxylase decreases expression ISO Mercury results in decreased expression of GGCX mRNA CTD PMID:17547211 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions
ISO
EXP
Mercury results in decreased expression of GGT1 mRNA
[Zinc co-treated with Copper co-treated with Manganese co-treated with Potassium Dichromate co-treated with Nickel co-treated with Cadmium co-treated with Lead co-treated with Mercury] affects the expression of GGT1 protein
CTD PMID:19937285 PMID:30090589 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gla galactosidase, alpha increases expression ISO Mercury results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glra3 glycine receptor, alpha 3 increases expression ISO Mercury results in increased expression of GLRA3 mRNA CTD PMID:16823088 NCBI chr16:34,199,937...34,848,773
Ensembl chr16:34,204,811...34,848,753
JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B decreases expression ISO Mercury analog results in decreased expression of GMPPB mRNA CTD PMID:25056781 NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286
JBrowse link
G Gngt1 G protein subunit gamma transducin 1 increases expression ISO Mercury results in increased expression of GNGT1 mRNA CTD PMID:16823088 NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 increases expression ISO Mercury results in increased expression of GNRH1 mRNA CTD PMID:16823088 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581
JBrowse link
G Golga1 golgin A1 decreases expression ISO Mercury analog results in decreased expression of GOLGA1 mRNA CTD PMID:25056781 NCBI chr 3:22,765,690...22,812,637
Ensembl chr 3:22,767,761...22,812,585
JBrowse link
G Golga3 golgin A3 decreases expression ISO Mercury analog results in decreased expression of GOLGA3 mRNA CTD PMID:25056781 NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509
Ensembl chr 4:46,454,870...46,500,509
JBrowse link
G Gorasp1 golgi reassembly stacking protein 1 decreases expression ISO Mercury analog results in decreased expression of GORASP1 mRNA CTD PMID:25056781 NCBI chr 8:119,655,267...119,667,022
Ensembl chr 8:119,655,268...119,666,972
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 decreases expression ISO Mercury results in decreased expression of GPER1 mRNA CTD PMID:17547211 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein] CTD PMID:37676925 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 affects response to substance
increases expression
ISO GPX1 gene SNP affects the susceptibility to Mercury
Mercury results in increased expression of GPX1 protein
CTD PMID:16451871 PMID:22236634 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsn gelsolin decreases expression
affects expression
ISO Mercury results in decreased expression of GSN mRNA
Mercury affects the expression of GSN protein
CTD PMID:17547211 PMID:22030286 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO
EXP
Mercury results in decreased activity of GSR protein
[Arsenic co-treated with Cadmium co-treated with Lead co-treated with Mercury co-treated with Chromium co-treated with Nickel co-treated with Manganese co-treated with Iron] results in decreased activity of GSR protein
CTD PMID:10798623 PMID:17176674 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gss glutathione synthetase affects abundance ISO GSS gene polymorphism affects the abundance of Mercury CTD PMID:21967774 NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects abundance ISO GSTA1 gene polymorphism affects the abundance of Mercury CTD PMID:19515364 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP Mercury results in increased expression of GSTA2 mRNA CTD PMID:12167210 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
multiple interactions
affects abundance
ISO GSTM1 gene polymorphism affects the susceptibility to Mercury; GSTM1 polymorphism affects the susceptibility to Mercury
[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury; [GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury; [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GSTM1 protein
GSTM1 gene polymorphism affects the abundance of Mercury
CTD PMID:17716707 PMID:19515364 PMID:20194072 PMID:24319713 PMID:25728017 More... NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
affects abundance
multiple interactions
EXP
ISO
Mercury results in increased expression of GSTP1 mRNA; Mercury results in increased expression of GSTP1 protein
GSTP1 gene affects the abundance of Mercury; GSTP1 gene polymorphism affects the abundance of Mercury
[GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury; GCLC gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury]; GSTT1 gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury]
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GSTP1 protein
CTD PMID:12167210 PMID:12730625 PMID:18560528 PMID:19515364 PMID:21967774 More... NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects abundance
multiple interactions
affects response to substance
ISO GSTT1 gene polymorphism affects the abundance of Mercury
[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury; GSTT1 gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury]
GSTT1 gene polymorphism affects the susceptibility to Mercury; GSTT1 polymorphism affects the susceptibility to Mercury
CTD PMID:17716707 PMID:19515364 PMID:20194072 PMID:21967774 PMID:24319713 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtpbp8 GTP binding protein 8 decreases expression ISO Mercury analog results in decreased expression of GTPBP8 mRNA CTD PMID:25056781 NCBI chr11:55,945,778...55,955,743
Ensembl chr11:55,945,795...55,955,635
JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 decreases expression ISO Mercury analog results in decreased expression of GXYLT2 mRNA CTD PMID:25056781 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454
JBrowse link
G Habp4 hyaluronan binding protein 4 increases expression ISO Mercury results in increased expression of HABP4 mRNA CTD PMID:16823088 NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions ISO [HAMP protein results in decreased expression of SLC11A2 mRNA] which results in decreased uptake of Mercury CTD PMID:25772431 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP Mercury results in increased expression of HAVCR1 mRNA; Mercury results in increased expression of HAVCR1 protein CTD PMID:17934191 PMID:25145654 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Heph hephaestin increases expression ISO Mercury results in increased expression of HEPH mRNA CTD PMID:16823088 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha decreases expression ISO Mercury results in decreased expression of HIF3A mRNA CTD PMID:19937285 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 decreases expression ISO Mercury analog results in decreased expression of HINT3 mRNA CTD PMID:25056781 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H increases expression ISO Mercury results in increased expression of H2AC11 mRNA CTD PMID:16823088 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hmgn2 high mobility group nucleosomal binding domain 2 increases expression ISO Mercury results in increased expression of HMGN2 mRNA CTD PMID:17547211 NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
Ensembl chr16:146,192,126...146,195,521
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; Mercury promotes the reaction [HSF1 protein binds to HMOX1 promoter]
[Benzo(a)pyrene co-treated with Mercury] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Mercury] results in increased expression of HMOX1 mRNA; [Mercury co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 protein; [Methylcholanthrene co-treated with Mercury] results in increased expression of HMOX1 mRNA; [Tetrachlorodibenzodioxin co-treated with Mercury] results in increased expression of HMOX1 mRNA; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HMOX1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 mRNA]; Mercury results in increased expression of and results in increased activity of HMOX1 protein; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [Mercury results in increased expression of HMOX mRNA]; Tetrachlorodibenzodioxin promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; U 0126 promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of HMOX1 protein]
CTD PMID:12730625 PMID:15297030 PMID:16093525 PMID:17244614 PMID:17547211 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf1a HNF1 homeobox A increases expression ISO Mercury results in increased expression of HNF1A mRNA CTD PMID:16823088 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
JBrowse link
G Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 increases expression ISO Mercury results in increased expression of HNRNPH3 mRNA CTD PMID:16823088 NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750
JBrowse link
G Hoxb4 homeo box B4 increases expression ISO Mercury results in increased expression of HOXB4 mRNA CTD PMID:19937285 NCBI chr10:81,284,552...81,287,134
Ensembl chr10:81,284,552...81,287,128
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO Mercury results in increased expression of HOXB6 mRNA CTD PMID:16823088 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
JBrowse link
G Hpx hemopexin affects expression ISO Mercury affects the expression of HPX protein CTD PMID:22030286 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions EXP Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer] CTD PMID:15111246 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hs1bp3 HCLS1 binding protein 3 decreases expression ISO Mercury results in decreased expression of HS1BP3 mRNA CTD PMID:16823088 NCBI chr 6:31,192,568...31,222,835
Ensembl chr 6:31,192,568...31,222,835
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
increases activity
ISO Mercury promotes the reaction [HSF1 protein binds to HMOX1 promoter]; Mercury promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Mercury results in increased activity of HSF1 protein
CTD PMID:17244614 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsf2 heat shock transcription factor 2 decreases expression ISO Mercury results in decreased expression of HSF2 mRNA CTD PMID:22008530 NCBI chr20:36,819,864...36,847,490
Ensembl chr20:36,819,864...36,850,174
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Mercury results in increased expression of HSP90AA1 mRNA CTD PMID:16823088 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
ISO Mercury promotes the reaction [HSF1 protein binds to HSPA1A promoter]
Mercury results in increased expression of HSPA1A mRNA
CTD PMID:17244614 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects response to substance ISO HSPA1B gene polymorphism affects the susceptibility to Mercury CTD PMID:23330093 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like affects response to substance ISO HSPA1L gene polymorphism affects the susceptibility to Mercury CTD PMID:23330093 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 affects expression
multiple interactions
EXP Mercury affects the expression of HSPA5 mRNA
Mercury promotes the reaction [HSPA5 protein binds to FOS enhancer]; Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer]; Mercury results in increased expression of and results in increased activity of HSPA5 protein
CTD PMID:15111246 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Mercury results in increased expression of HSPD1 mRNA CTD PMID:12730625 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 increases expression ISO Mercury results in increased expression of HTR7 mRNA CTD PMID:16823088 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Ifi44 interferon-induced protein 44 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFI44 mRNA CTD PMID:28453771 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Ifng interferon gamma affects expression
decreases secretion
increases expression
multiple interactions
ISO Mercury affects the expression of IFNG mRNA; Mercury affects the expression of IFNG protein
Mercury results in decreased secretion of IFNG protein
Mercury results in increased expression of IFNG protein
Mercury results in increased expression of IFNG mRNA
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG protein; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of IFNG mRNA]
CTD PMID:12928768 PMID:15910788 PMID:20176347 PMID:25237059 PMID:28453771 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 affects response to substance ISO IFNGR1 affects the susceptibility to Mercury CTD PMID:22578563 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Mercury results in decreased expression of IFRD1 mRNA CTD PMID:17547211 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il10 interleukin 10 increases expression ISO Mercury results in increased expression of IL10 mRNA CTD PMID:16045731 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13 interleukin 13 increases expression ISO Mercury results in increased expression of IL13 mRNA CTD PMID:37137463 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il17rb interleukin 17 receptor B decreases expression ISO Mercury results in decreased expression of IL17RB mRNA CTD PMID:17547211 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Mercury results in increased expression of IL1B protein
Mercury promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
Mercury results in increased expression of IL1B mRNA; Mercury results in increased expression of IL1B protein
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL1B mRNA; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of IL1B mRNA]
CTD PMID:20176347 PMID:20600710 PMID:25237059 PMID:28453771 PMID:37137463 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 increases expression EXP Mercury results in increased expression of IL2 mRNA CTD PMID:12730625 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il33 interleukin 33 decreases expression ISO Mercury analog results in decreased expression of IL33 mRNA CTD PMID:25056781 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il3ra interleukin 3 receptor subunit alpha decreases expression ISO Mercury results in decreased expression of IL3RA mRNA CTD PMID:16823088 NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484
JBrowse link
G Il4 interleukin 4 decreases secretion
multiple interactions
ISO Mercury results in decreased secretion of IL4 protein
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]
CTD PMID:15910788 PMID:28453771 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Mercury results in increased expression of IL6 protein
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL6 mRNA; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; Salicylic Acid inhibits the reaction [Mercury results in increased expression of IL6]
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of IL6 protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]
CTD PMID:18393961 PMID:23742082 PMID:28453771 PMID:37415728 PMID:37676925 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impg1 interphotoreceptor matrix proteoglycan 1 increases expression ISO Mercury results in increased expression of IMPG1 mRNA CTD PMID:16823088 NCBI chr 8:81,243,624...81,389,722
Ensembl chr 8:81,243,624...81,389,722
JBrowse link
G Ins1 insulin 1 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] inhibits the reaction [Glucose results in increased secretion of INS1 protein] CTD PMID:33038468 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Irf1 interferon regulatory factor 1 affects response to substance
multiple interactions
ISO IRF1 affects the susceptibility to Mercury
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]
CTD PMID:22578563 PMID:28453771 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA] CTD PMID:28453771 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Cadmium co-treated with Mercury] results in increased phosphorylation of IRS1 protein CTD PMID:30629257 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Mercury analog results in decreased expression of ISG15 mRNA CTD PMID:25056781 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itgb1 integrin subunit beta 1 increases activity EXP Mercury results in increased activity of ITGB1 protein CTD PMID:10820171 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO Mercury results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 affects expression ISO Mercury affects the expression of ITIH1 protein CTD PMID:22030286 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO Mercury results in decreased expression of ITIH3 mRNA CTD PMID:17547211 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression ISO Mercury affects the expression of ITIH4 protein CTD PMID:22030286 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Ivns1abp influenza virus NS1A binding protein decreases expression ISO Mercury results in decreased expression of IVNS1ABP mRNA CTD PMID:16823088 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jak2 Janus kinase 2 affects expression ISO Mercury affects the expression of JAK2 mRNA CTD PMID:23920476 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
EXP
ISO
Mercury results in decreased expression of JUN mRNA
[Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of JUN protein
CTD PMID:12730625 PMID:28035397 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 increases expression ISO Mercury results in increased expression of KCNH2 mRNA CTD PMID:16823088 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 decreases expression ISO Mercury analog results in decreased expression of KDELR2 mRNA CTD PMID:25056781 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Klf12 KLF transcription factor 12 decreases expression ISO Mercury results in decreased expression of KLF12 mRNA CTD PMID:19937285 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Klf2 KLF transcription factor 2 decreases expression ISO Mercury results in decreased expression of KLF2 mRNA CTD PMID:19937285 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Kmt2b lysine methyltransferase 2B increases expression ISO Mercury results in increased expression of KMT2B mRNA CTD PMID:16823088 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
JBrowse link
G Krt1 keratin 1 increases expression ISO Mercury results in increased expression of KRT1 mRNA CTD PMID:19937285 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Lamc1 laminin subunit gamma 1 decreases expression ISO Mercury analog results in decreased expression of LAMC1 mRNA CTD PMID:25056781 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 decreases expression ISO Mercury results in decreased expression of LANCL1 mRNA CTD PMID:16823088 NCBI chr 9:68,515,052...68,548,646
Ensembl chr 9:68,518,574...68,548,628
JBrowse link
G Lancl2 LanC like glutathione S-transferase 2 decreases expression ISO Mercury results in decreased expression of LANCL2 mRNA CTD PMID:19937285 NCBI chr 4:87,441,821...87,483,707
Ensembl chr 4:87,441,823...87,482,800
JBrowse link
G Lcn2 lipocalin 2 increases expression EXP Mercury results in increased expression of LCN2 mRNA CTD PMID:25145654 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Leng9 leukocyte receptor cluster member 9 decreases expression ISO Mercury analog results in decreased expression of LENG9 mRNA CTD PMID:25056781 NCBI chr 1:70,039,099...70,041,559
Ensembl chr 1:70,035,791...70,044,509
JBrowse link
G Lepr leptin receptor decreases expression ISO Mercury results in decreased expression of LEPR mRNA CTD PMID:16823088 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Limd1 LIM domain containing 1 decreases expression ISO Mercury analog results in decreased expression of LIMD1 mRNA CTD PMID:25056781 NCBI chr 8:123,121,363...123,168,476
Ensembl chr 8:123,122,460...123,167,714
JBrowse link
G Lims2 LIM zinc finger domain containing 2 decreases expression ISO Mercury analog results in decreased expression of LIMS2 mRNA CTD PMID:25056781 NCBI chr18:23,553,937...23,592,137
Ensembl chr18:23,553,937...23,592,137
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO Mercury results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Lmbr1 limb development membrane protein 1 decreases expression ISO Mercury analog results in decreased expression of LMBR1 mRNA CTD PMID:25056781 NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
JBrowse link
G Lmna lamin A/C decreases expression ISO Mercury results in decreased expression of LMNA mRNA CTD PMID:16823088 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 increases expression ISO Mercury results in increased expression of LRRFIP1 mRNA CTD PMID:16823088 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated decreases expression ISO Mercury analog results in decreased expression of LSM5 mRNA CTD PMID:25056781 NCBI chr 4:85,951,073...85,954,289
Ensembl chr 6:104,652,477...104,654,165
Ensembl chr 4:104,652,477...104,654,165
JBrowse link
G Ltf lactotransferrin increases expression ISO Mercury results in increased expression of LTF protein CTD PMID:37137463 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO Mercury results in increased phosphorylation of and results in increased activity of LYN protein CTD PMID:24440445 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 decreases expression ISO Mercury analog results in decreased expression of LZTS2 mRNA CTD PMID:25056781 NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 increases expression ISO Mercury results in increased expression of MACF1 mRNA CTD PMID:16823088 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Mercury results in increased expression of MAFF mRNA CTD PMID:19937285 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mageb1 MAGE family member B1 increases expression ISO Mercury results in increased expression of MAGEB4 mRNA CTD PMID:16823088 NCBI chr  X:50,915,789...50,921,863 JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 affects expression ISO Mercury affects the expression of MAN1B1 mRNA CTD PMID:23920476 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of MAP2 mRNA CTD PMID:37914285 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases expression ISO Mercury results in increased expression of MAP2K2 mRNA CTD PMID:16823088 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Map9 microtubule-associated protein 9 increases expression ISO Mercury results in increased expression of MAP9 mRNA CTD PMID:19937285 NCBI chr 2:167,708,661...167,743,927
Ensembl chr 2:167,708,765...167,740,736
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Mercury results in increased phosphorylation of MAPK1 protein CTD PMID:21994240 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Mercury results in increased phosphorylation of MAPK3 protein CTD PMID:21994240 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO Mercury results in increased expression of MCM2 mRNA CTD PMID:17547211 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Med16 mediator complex subunit 16 increases expression ISO Mercury results in increased expression of MED16 mRNA CTD PMID:16823088 NCBI chr 7:9,798,641...9,811,172
Ensembl chr 7:9,798,668...9,811,172
JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression ISO Mercury results in increased expression of MEOX2 mRNA CTD PMID:16823088 NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
JBrowse link
G Mfap5 microfibril associated protein 5 increases expression ISO Mercury results in increased expression of MFAP5 mRNA CTD PMID:16823088 NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO Mercury results in decreased expression of MGAT2 mRNA CTD PMID:17547211 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase increases expression EXP Mercury results in increased expression of MGAT5 mRNA CTD PMID:22688007 NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513
JBrowse link
G Mir10a microRNA 10a decreases expression ISO Mercury results in decreased expression of MIR10A mRNA CTD PMID:26252056 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
JBrowse link
G Mir151 microRNA 151 decreases expression ISO Mercury results in decreased expression of MIR151A mRNA CTD PMID:26252056 NCBI chr 7:105,172,377...105,172,473 JBrowse link
G Mir190b microRNA 190b decreases expression ISO Mercury results in decreased expression of MIR190B mRNA CTD PMID:26252056 NCBI chr 2:175,514,800...175,514,877
Ensembl chr 2:175,514,800...175,514,877
JBrowse link
G Mir193b microRNA 193b decreases expression ISO Mercury results in decreased expression of MIR193B mRNA CTD PMID:26252056 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824
JBrowse link
G Mir423 microRNA 423 decreases expression ISO Mercury results in decreased expression of MIR423 mRNA CTD PMID:26252056 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir96 microRNA 96 decreases expression ISO Mercury results in decreased expression of MIR96 mRNA CTD PMID:26252056 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mirlet7b microRNA let-7b decreases expression ISO Mercury results in decreased expression of MIRLET7B mRNA CTD PMID:26252056 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mirlet7c1 microRNA let-7c-1 decreases expression ISO Mercury results in decreased expression of MIRLET7C mRNA CTD PMID:26252056 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Mirlet7d microRNA let-7d decreases expression ISO Mercury results in decreased expression of MIRLET7D mRNA CTD PMID:26252056 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
JBrowse link
G Mirlet7g microRNA let-7g decreases expression ISO Mercury results in decreased expression of MIRLET7G mRNA CTD PMID:26252056 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
JBrowse link
G Mirlet7i microRNA let-7i decreases expression ISO Mercury results in decreased expression of MIRLET7I mRNA CTD PMID:26252056 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mme membrane metallo-endopeptidase increases expression
multiple interactions
ISO Mercury results in increased expression of MME protein
Mercury affects the folding of and results in decreased activity of MME protein
CTD PMID:25673500 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Mercury affects the reaction [MMP2 promoter polymorphism results in increased expression of MMP2 protein] CTD PMID:21794897 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects response to substance ISO MMP9 promoter polymorphism affects the susceptibility to Mercury CTD PMID:20554312 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Morf4l2 mortality factor 4 like 2 decreases expression ISO Mercury results in decreased expression of MORF4L2 mRNA CTD PMID:16823088 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728
JBrowse link
G Mpo myeloperoxidase decreases activity ISO Mercury results in decreased activity of MPO protein CTD PMID:15557676 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrps23 mitochondrial ribosomal protein S23 decreases expression ISO Mercury analog results in decreased expression of MRPS23 mRNA CTD PMID:25056781 NCBI chr10:72,999,033...73,006,791
Ensembl chr10:72,998,497...73,006,264
JBrowse link
G Msh6 mutS homolog 6 increases expression ISO Mercury results in increased expression of MSH6 mRNA CTD PMID:19937285 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msl3 MSL complex subunit 3 decreases expression ISO Mercury analog results in decreased expression of MSL3 mRNA CTD PMID:25056781 NCBI chr  X:25,638,029...25,655,698
Ensembl chr  X:25,637,804...25,655,697
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of MSR1 mRNA CTD PMID:28453771 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt1 metallothionein 1 increases expression
affects abundance
multiple interactions
affects binding
increases response to substance
EXP
ISO
Mercury results in increased expression of MT1 mRNA; Mercury results in increased expression of MT1 protein; Mercury results in increased expression of MT1A mRNA
MT1A gene polymorphism affects the abundance of Mercury; MT1A gene SNP affects the abundance of Mercury
[MT1 co-treated with MT2] affects the susceptibility to Mercury
Mercury binds to MT1 protein
MT1 gene mutant form results in increased susceptibility to Mercury
CTD PMID:8917669 PMID:9462895 PMID:9587011 PMID:12167210 PMID:12730625 More... NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049
JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 affects response to substance ISO MT1E gene SNP affects the susceptibility to Mercury CTD PMID:22236634 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Mt2A metallothionein 2A affects abundance
affects binding
increases expression
increases response to substance
multiple interactions
affects response to substance
ISO
EXP
MT2A gene SNP affects the abundance of Mercury
Mercury binds to MT2 protein
Mercury results in increased expression of MT2 mRNA; Mercury results in increased expression of MT2 protein
MT2 gene mutant form results in increased susceptibility to Mercury
[MT1 co-treated with MT2] affects the susceptibility to Mercury; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA
[MT1M gene polymorphism co-treated with MT2A gene polymorphism] affects the susceptibility to Mercury
MT2A gene polymorphism affects the susceptibility to Mercury
Mercury results in increased expression of MT2A mRNA
CTD PMID:2771874 PMID:8917669 PMID:9462895 PMID:9587011 PMID:15138662 More... NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mt3 metallothionein 3 affects binding
increases expression
multiple interactions
affects response to substance
ISO
EXP
Mercury binds to MT3 protein
Mercury results in increased expression of MT3 mRNA; Mercury results in increased expression of MT3 protein
[MT3 protein affects the susceptibility to Mercury] which affects the expression of CCL7 mRNA; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA; MT3 protein affects the reaction [Mercury results in increased expression of CCL3 mRNA]
CTD PMID:8917669 PMID:9587011 PMID:15138662 PMID:15782327 PMID:17018868 More... NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mt4 metallothionein 4 affects abundance ISO MT4 gene polymorphism affects the abundance of Mercury CTD PMID:19515364 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 increases expression ISO Mercury results in increased expression of MTF1 mRNA CTD PMID:16823088 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mtmr11 myotubularin related protein 11 decreases expression ISO Mercury results in decreased expression of MTMR11 mRNA CTD PMID:16823088 NCBI chr 2:183,721,983...183,732,148
Ensembl chr 2:183,723,530...183,732,148
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions ISO Mercury inhibits the reaction [[Hydroxocobalamin co-treated with S-Adenosylmethionine] results in increased activity of MTR protein alternative form]; Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein]; Mercury inhibits the reaction [mecobalamin results in increased activity of MTR protein alternative form] CTD PMID:14745455 PMID:26989453 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
JBrowse link
G Mtrf1 mitochondrial translation release factor 1 decreases expression ISO Mercury results in decreased expression of MTRF1 mRNA CTD PMID:19937285 NCBI chr15:54,776,885...54,804,699
Ensembl chr15:54,776,937...54,804,704
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming increases expression ISO Mercury results in increased expression of MUC2 mRNA CTD PMID:37137463 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Mvb12b multivesicular body subunit 12B increases expression ISO Mercury results in increased expression of MVB12B mRNA CTD PMID:16823088 NCBI chr 3:17,034,002...17,192,658
Ensembl chr 3:17,034,003...17,193,202
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
affects expression
ISO Mercury results in decreased expression of MYC mRNA
Mercury affects the expression of MYC mRNA
CTD PMID:12928768 PMID:16823088 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myo1b myosin Ib increases expression
decreases expression
ISO Mercury results in increased expression of MYO1B mRNA
Mercury analog results in decreased expression of MYO1B mRNA
CTD PMID:16823088 PMID:25056781 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
JBrowse link
G Mzf1 myeloid zinc finger 1 decreases expression ISO Mercury analog results in decreased expression of MZF1 mRNA CTD PMID:25056781 NCBI chr 1:73,670,522...73,682,885
Ensembl chr 1:73,670,541...73,681,635
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression ISO Mercury results in increased expression of NAP1L1 mRNA CTD PMID:16823088 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions ISO Mercury binds to and results in decreased activity of NAT1 protein CTD PMID:20591428 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Nav3 neuron navigator 3 increases expression ISO Mercury results in increased expression of NAV3 mRNA CTD PMID:16823088 NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
JBrowse link
G Ncapd3 non-SMC condensin II complex, subunit D3 increases expression
decreases expression
ISO Mercury results in increased expression of NCAPD3 mRNA
Mercury analog results in decreased expression of NCAPD3 mRNA
CTD PMID:19937285 PMID:25056781 NCBI chr 8:25,437,067...25,506,375
Ensembl chr 8:25,437,123...25,506,373
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 increases expression ISO Mercury results in increased expression of NCOA3 mRNA CTD PMID:16823088 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Mercury results in decreased expression of NDUFS2 mRNA CTD PMID:16823088 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases expression ISO Mercury results in increased expression of NFATC4 mRNA CTD PMID:19937285 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
increases activity
ISO
EXP
NFE2L2 protein affects the reaction [Mercury results in increased expression of GSTA1 mRNA]; NFE2L2 protein affects the reaction [Mercury results in increased expression of NQO1 mRNA]
Mercury results in increased expression of NFE2L2 mRNA
Mercury results in increased activity of NFE2L2 promoter
[Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of NFE2L2 protein
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased expression of NFE2L2 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased expression of NFE2L2 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased expression of NFE2L2 protein; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NFE2L2 protein]
CTD PMID:16243960 PMID:21643505 PMID:27837179 PMID:30359721 PMID:37415728 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP
Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased activity of NFKB1 protein]
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Zinc] results in decreased expression of NFKB1 protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in decreased expression of NFKB1 protein; Mercury inhibits the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]]
CTD PMID:11437639 PMID:15282405 PMID:37415728 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:11437639 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngf nerve growth factor increases expression
decreases expression
ISO
EXP
Mercury results in increased expression of NGF mRNA
Mercury results in decreased expression of NGF mRNA
CTD PMID:7781173 PMID:16823088 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Mercury results in decreased expression of NGFR mRNA CTD PMID:7781173 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 increases expression ISO Mercury results in increased expression of NHERF2 mRNA CTD PMID:16823088 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A decreases expression ISO Mercury results in decreased expression of NLRP1 mRNA CTD PMID:19937285 NCBI chr10:55,778,560...55,833,639
Ensembl chr10:55,778,560...55,825,180
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression
multiple interactions
ISO Mercury results in increased expression of NLRP3 mRNA
N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of NLRP3 mRNA]
CTD PMID:25237059 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nmt2 N-myristoyltransferase 2 increases expression ISO Mercury results in increased expression of NMT2 mRNA CTD PMID:16823088 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 decreases expression ISO Mercury results in decreased expression of NOD1 mRNA CTD PMID:19937285 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of NOX4 protein CTD PMID:30359721 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases activity
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; Buthionine Sulfoximine promotes the reaction [Mercury results in increased expression of NQO1 mRNA]; Buthionine Sulfoximine promotes the reaction [Mercury results in increased expression of NQO1 protein]; Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Mercury results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 protein affects the reaction [Mercury results in increased expression of NQO1 mRNA]; prolinedithiocarbamate promotes the reaction [Mercury results in increased expression of NQO1 protein]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; pyrazolanthrone inhibits the reaction [Mercury results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 protein]; U 0126 promotes the reaction [Mercury results in increased expression of NQO1 mRNA]; U 0126 promotes the reaction [Mercury results in increased expression of NQO1 protein]
Mercury results in increased activity of NQO1 protein
Mercury results in increased expression of NQO1 mRNA; Mercury results in increased expression of NQO1 protein
Acetylcysteine inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]
CTD PMID:16243960 PMID:18752316 PMID:22579925 PMID:26600472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression EXP Mercury results in decreased expression of NR4A1 mRNA CTD PMID:12730625 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nsrp1 nuclear speckle splicing regulatory protein 1 decreases expression ISO Mercury analog results in decreased expression of NSRP1 mRNA CTD PMID:25056781 NCBI chr10:61,880,807...61,914,471
Ensembl chr10:61,880,825...61,914,471
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO Mercury results in increased expression of NTRK3 mRNA CTD PMID:19937285 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Nup107 nucleoporin 107 increases expression ISO Mercury results in increased expression of NUP107 mRNA CTD PMID:17547211 NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370
JBrowse link
G Ocln occludin decreases expression ISO Mercury results in decreased expression of OCLN mRNA CTD PMID:37137463 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Mercury results in decreased expression of OGG1 mRNA CTD PMID:22641096 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP Mercury inhibits the reaction [enkephalin, Ser(2), Leu(5), Thr(6)- binds to OPRD1 protein] CTD PMID:2162496 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprk1 opioid receptor, kappa 1 multiple interactions EXP Mercury inhibits the reaction [Ethylketocyclazocine binds to OPRK1 protein] CTD PMID:2162496 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP Mercury inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to OPRM1 protein] CTD PMID:2162496 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin decreases expression ISO Mercury results in decreased expression of OS9 mRNA CTD PMID:17547211 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
JBrowse link
G P2rx2 purinergic receptor P2X 2 multiple interactions EXP Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]; methyl methanethiosulfonate inhibits the reaction [Mercury promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]] CTD PMID:19793987 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
JBrowse link
G P2rx4 purinergic receptor P2X 4 multiple interactions EXP [Mercury co-treated with Copper] inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]; Mercury inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein] CTD PMID:10737610 PMID:15629187 PMID:19793987 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression
affects binding
ISO Mercury results in increased expression of PARK7 mRNA
Mercury binds to PARK7 protein
CTD PMID:16823088 PMID:23792957 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein; Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax6 paired box 6 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of PAX6 mRNA CTD PMID:37914285 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pcdhb5 protocadherin beta 5 decreases expression ISO Mercury results in decreased expression of PCDHB4 mRNA CTD PMID:22008530 NCBI chr18:29,024,315...29,032,183
Ensembl chr18:29,028,382...29,053,259
JBrowse link
G Pde1a phosphodiesterase 1A decreases expression ISO Mercury results in decreased expression of PDE1A mRNA CTD PMID:22008530 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein increases expression ISO Mercury results in increased expression of PDE4DIP mRNA CTD PMID:16823088 NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Mercury results in decreased expression of PDIA4 mRNA CTD PMID:17547211 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pds5b PDS5 cohesin associated factor B decreases expression ISO Mercury results in decreased expression of PDS5B mRNA CTD PMID:16823088 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
JBrowse link
G Pex14 peroxisomal biogenesis factor 14 increases expression ISO Mercury results in increased expression of PEX14 mRNA CTD PMID:16823088 NCBI chr 5:159,399,776...159,536,260
Ensembl chr 5:159,399,776...159,536,272
JBrowse link
G Pfdn4 prefoldin subunit 4 decreases expression ISO Mercury analog results in decreased expression of PFDN4 mRNA CTD PMID:25056781 NCBI chr 3:159,303,173...159,311,221
Ensembl chr 3:159,303,071...159,311,219
JBrowse link
G Pgc progastricsin decreases expression ISO Mercury results in decreased expression of PGC mRNA CTD PMID:17547211 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682
JBrowse link
G Phox2b paired-like homeobox 2b increases expression ISO Mercury results in increased expression of PHOX2B mRNA CTD PMID:16823088 NCBI chr14:41,066,012...41,069,202
Ensembl chr14:41,066,264...41,068,978
JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 affects expression ISO Mercury affects the expression of PIAS2 mRNA CTD PMID:23920476 NCBI chr18:70,608,034...70,714,295
Ensembl chr18:70,607,665...70,710,033
JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 decreases expression EXP Mercury results in decreased expression of PIAS4 mRNA CTD PMID:22688007 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Mercury results in decreased expression of PIK3R1 mRNA CTD PMID:12730625 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 increases expression ISO Mercury results in increased expression of PIK3R4 mRNA CTD PMID:16823088 NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing decreases expression ISO Mercury results in decreased expression of PIKFYVE mRNA CTD PMID:19937285 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pld1 phospholipase D1 increases phosphorylation ISO Mercury results in increased phosphorylation of PLD1 protein CTD PMID:21994240 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plppr4 phospholipid phosphatase related 4 increases expression ISO Mercury results in increased expression of PLPPR4 mRNA CTD PMID:16823088 NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302
JBrowse link
G Plxnb3 plexin B3 decreases expression ISO Mercury analog results in decreased expression of PLXNB3 mRNA CTD PMID:25056781 NCBI chr  X:151,493,832...151,508,688
Ensembl chr  X:151,494,207...151,508,674
JBrowse link
G Pmch pro-melanin-concentrating hormone decreases expression ISO Mercury results in decreased expression of PMCH mRNA CTD PMID:19937285 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component decreases expression ISO Mercury analog results in decreased expression of PMS1 mRNA CTD PMID:25056781 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237
JBrowse link
G Pnma1 PNMA family member 1 decreases expression ISO Mercury results in decreased expression of PNMA1 mRNA CTD PMID:17547211 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567
JBrowse link
G Pogk pogo transposable element derived with KRAB domain affects expression ISO Mercury affects the expression of POGK mRNA CTD PMID:16823088 NCBI chr13:78,647,447...78,663,363
Ensembl chr13:78,647,447...78,663,363
JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit affects expression ISO Mercury affects the expression of POLD2 mRNA CTD PMID:16823088 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
JBrowse link
G Pon1 paraoxonase 1 decreases activity
multiple interactions
ISO Mercury results in decreased activity of PON1 protein
Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein]
CTD PMID:21543280 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pou2f3 POU class 2 homeobox 3 increases expression ISO Mercury results in increased expression of POU2F3 mRNA CTD PMID:16823088 NCBI chr 8:43,495,408...43,577,795
Ensembl chr 8:43,495,527...43,577,795
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression ISO Mercury results in increased expression of PPIA mRNA CTD PMID:16823088 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppih peptidylprolyl isomerase H increases expression ISO Mercury results in increased expression of PPIH mRNA CTD PMID:17547211 NCBI chr 5:132,906,324...132,924,341
Ensembl chr 5:132,906,328...132,924,267
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases expression ISO Mercury results in increased expression of PPP1R12A mRNA CTD PMID:16823088 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression ISO Mercury results in decreased expression of PPP1R15A mRNA CTD PMID:16823088 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta decreases expression ISO Mercury results in decreased expression of PPP3CB mRNA CTD PMID:22008530 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Pprc1 PPARG related coactivator 1 affects response to substance ISO PPRC1 protein affects the susceptibility to Mercury CTD PMID:26942574 NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
JBrowse link
G Ppt2 palmitoyl-protein thioesterase 2 decreases expression ISO Mercury results in decreased expression of PPT2 mRNA CTD PMID:19937285 NCBI chr20:4,112,520...4,132,774
Ensembl chr20:4,122,463...4,132,774
JBrowse link
G Prdx2 peroxiredoxin 2 increases expression EXP Mercury results in increased expression of PRDX2 mRNA CTD PMID:12730625 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression
increases expression
ISO Mercury results in decreased expression of PRDX6 mRNA
Mercury analog results in increased expression of PRDX6 mRNA
CTD PMID:16823088 PMID:25056781 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP Mercury results in increased expression of PRKCA mRNA CTD PMID:12730625 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcg protein kinase C, gamma increases expression EXP Mercury results in increased expression of PRKCG mRNA CTD PMID:12730625 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Prkcq protein kinase C, theta decreases expression ISO Mercury analog results in decreased expression of PRKCQ mRNA CTD PMID:25056781 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Prpf31 pre-mRNA processing factor 31 decreases expression ISO Mercury analog results in decreased expression of PRPF31 mRNA CTD PMID:25056781 NCBI chr 1:65,575,887...65,587,561
Ensembl chr 1:65,575,887...65,587,873
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A decreases expression ISO Mercury analog results in decreased expression of PRPF40A mRNA CTD PMID:25056781 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Psph phosphoserine phosphatase decreases expression ISO Mercury results in decreased expression of PSPH mRNA CTD PMID:17547211 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 decreases expression ISO Mercury analog results in decreased expression of PTBP1 mRNA CTD PMID:25056781 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
JBrowse link
G Ptger2 prostaglandin E receptor 2 increases expression EXP Mercury results in increased expression of PTGER2 mRNA CTD PMID:12730625 NCBI chr15:18,215,013...18,228,714
Ensembl chr15:18,217,285...18,228,714
JBrowse link
G Ptov1 PTOV1, extended AT-hook containing adaptor protein decreases expression ISO Mercury analog results in decreased expression of PTOV1 mRNA CTD PMID:25056781 NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO Mercury results in increased expression of PTTG1 mRNA CTD PMID:17547211 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Purb purine rich element binding protein B increases expression ISO Mercury analog results in increased expression of PURB mRNA CTD PMID:25056781 NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432
JBrowse link
G Pvalb parvalbumin decreases expression ISO Mercury analog results in decreased expression of PVALB mRNA CTD PMID:25056781 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Pxdn peroxidasin decreases expression ISO Mercury results in decreased expression of PXDN mRNA CTD PMID:19937285 NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345
JBrowse link
G Pxn paxillin affects localization ISO Mercury affects the localization of PXN protein CTD PMID:26600472 NCBI chr12:41,060,791...41,107,952
Ensembl chr12:41,060,791...41,107,931
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression ISO Mercury results in increased expression of RAC1 mRNA CTD PMID:16823088 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression ISO Mercury results in increased expression of RACGAP1 mRNA CTD PMID:17547211 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase decreases expression ISO Mercury results in decreased expression of RAD18 mRNA CTD PMID:22641096 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069
JBrowse link
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 decreases expression ISO Mercury results in decreased expression of RALGAPA1 mRNA CTD PMID:19937285 NCBI chr 6:72,977,432...73,252,378
Ensembl chr 6:72,977,432...73,252,378
JBrowse link
G Rara retinoic acid receptor, alpha decreases expression EXP Mercury results in decreased expression of RARA mRNA CTD PMID:22688007 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rbfox3 RNA binding fox-1 homolog 3 multiple interactions ISO [diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of RBFOX3 mRNA CTD PMID:37914285 NCBI chr10:103,720,355...104,157,277
Ensembl chr10:103,720,636...104,156,935
JBrowse link
G Rbm22 RNA binding motif protein 22 decreases expression ISO Mercury analog results in decreased expression of RBM22 mRNA CTD PMID:25056781 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Mercury results in increased expression of RBPMS mRNA CTD PMID:17547211 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
Mercury inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased localization of RELA protein]
Mercury inhibits the reaction [Lipopolysaccharides results in increased activity of [RELA protein binds to NFKB1 protein]]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]]
[Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of RELA protein
CTD PMID:11437639 PMID:15282405 PMID:28035397 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Reln reelin decreases expression ISO Mercury results in decreased expression of RELN mRNA CTD PMID:17547211 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Rhobtb2 Rho-related BTB domain containing 2 increases expression ISO Mercury results in increased expression of RHOBTB2 mRNA CTD PMID:16823088 NCBI chr15:44,868,251...44,888,436
Ensembl chr15:44,870,376...44,888,651
JBrowse link
G Rnaseh1 ribonuclease H1 decreases expression ISO Mercury results in decreased expression of RNASEH1 mRNA CTD PMID:16823088 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
JBrowse link
G Rnaseh2a ribonuclease H2, subunit A decreases expression
increases expression
ISO Mercury results in decreased expression of RNASEH2A mRNA
Mercury results in increased expression of RNASEH2A mRNA
CTD PMID:16823088 PMID:17547211 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041
JBrowse link
G Rnd2 Rho family GTPase 2 increases methylation ISO Mercury results in increased methylation of RND2 gene CTD PMID:21606628 NCBI chr10:86,399,151...86,402,750
Ensembl chr10:86,399,148...86,402,742
JBrowse link
G Rnf138 ring finger protein 138 increases expression ISO Mercury results in increased expression of RNF138 mRNA CTD PMID:16823088 NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
JBrowse link
G rnf141 ring finger protein 141 decreases expression ISO Mercury results in decreased expression of RNF141 mRNA CTD PMID:19937285 NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
JBrowse link
G Rngtt RNA guanylyltransferase and 5'-phosphatase affects expression ISO Mercury affects the expression of RNGTT mRNA CTD PMID:16823088 NCBI chr 5:47,706,929...47,913,297
Ensembl chr 5:47,706,799...47,913,295
JBrowse link
G Rpl19 ribosomal protein L19 decreases expression ISO Mercury results in decreased expression of RPL19 mRNA CTD PMID:16823088 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112
JBrowse link
G Rpl28 ribosomal protein L28 decreases expression ISO Mercury results in decreased expression of RPL28 mRNA CTD PMID:16823088 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 decreases expression ISO Mercury analog results in decreased expression of RPP21 mRNA CTD PMID:25056781 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106
JBrowse link
G Rps5 ribosomal protein S5 decreases expression ISO Mercury results in decreased expression of RPS5 mRNA CTD PMID:16823088 NCBI chr 1:73,538,776...73,543,073
Ensembl chr 1:73,538,776...73,543,073
JBrowse link
G Rps6kc1 ribosomal protein S6 kinase C1 decreases expression ISO Mercury analog results in decreased expression of RPS6KC1 mRNA CTD PMID:25056781 NCBI chr13:102,346,160...102,491,000
Ensembl chr13:102,346,160...102,490,303
JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO Mercury results in decreased expression of RRBP1 mRNA CTD PMID:19937285 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions ISO [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of RSAD2 mRNA CTD PMID:28453771 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-Ba RT1 class II, locus Ba decreases expression ISO Mercury results in decreased expression of HLA-DQA1 mRNA CTD PMID:16823088 PMID:19937285 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression
decreases expression
EXP
ISO
Mercury results in increased expression of RT1-BB mRNA
Mercury results in increased expression of HLA-DQB1 mRNA
Mercury results in decreased expression of HLA-DQB1 mRNA
CTD PMID:16823088 PMID:19937285 PMID:22688007 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G Rtn4 reticulon 4 decreases expression ISO Mercury results in decreased expression of RTN4 mRNA CTD PMID:19937285 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Rtp3 receptor (chemosensory) transporter protein 3 decreases expression ISO Mercury results in decreased expression of RTP3 mRNA CTD PMID:22008530 NCBI chr 8:110,970,154...110,975,000
Ensembl chr 8:110,970,160...110,974,699
JBrowse link
G Rubcnl rubicon like autophagy enhancer increases expression ISO Mercury results in increased expression of RUBCNL mRNA CTD PMID:16823088 NCBI chr15:50,332,458...50,377,494
Ensembl chr15:50,332,418...50,400,849
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression ISO Mercury analog results in decreased expression of S100A4 mRNA CTD PMID:25056781 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100b S100 calcium binding protein B increases secretion ISO Mercury results in increased secretion of S100B mRNA CTD PMID:30076900 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
JBrowse link
G Sap30 Sin3A associated protein 30 increases expression ISO Mercury results in increased expression of SAP30 mRNA CTD PMID:16823088 NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112
JBrowse link
G Scaf4 SR-related CTD-associated factor 4 increases expression ISO Mercury results in increased expression of SCAF4 mRNA CTD PMID:16823088 NCBI chr11:29,460,479...29,521,153
Ensembl chr11:29,465,106...29,521,153
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO Mercury results in increased expression of SCARB1 mRNA CTD PMID:19937285 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scg3 secretogranin III increases expression ISO Mercury results in increased expression of SCG3 mRNA CTD PMID:16823088 NCBI chr 8:76,399,777...76,442,015
Ensembl chr 8:76,399,777...76,442,015
JBrowse link
G Sec24c SEC24 homolog C, COPII coat complex component increases expression ISO Mercury results in increased expression of SEC24C mRNA CTD PMID:16823088 NCBI chr15:3,602,460...3,624,524
Ensembl chr15:3,602,460...3,624,422
JBrowse link
G Selenop selenoprotein P affects abundance
increases expression
multiple interactions
ISO SELENOP gene polymorphism affects the abundance of Mercury
Mercury results in increased expression of SELENOP protein
[Mercury results in increased expression of SELENOP protein] which results in increased abundance of Selenium; SELENOP protein binds to and results in decreased susceptibility to Mercury
CTD PMID:16451871 PMID:21967774 PMID:27989593 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
JBrowse link
G Senp6 SUMO specific peptidase 6 increases expression ISO Mercury results in increased expression of SENP6 mRNA CTD PMID:16823088 NCBI chr 8:80,988,675...81,071,606
Ensembl chr 8:80,989,052...81,067,170
JBrowse link
G Serpina3n serpin family A member 3N affects expression ISO Mercury affects the expression of SERPINA3 protein CTD PMID:22030286 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Mercury results in decreased expression of SERPINB1 mRNA CTD PMID:17547211 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO Mercury results in decreased expression of SERPINC1 mRNA CTD PMID:17547211 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serping1 serpin family G member 1 affects expression ISO Mercury affects the expression of SERPING1 protein CTD PMID:22030286 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 decreases expression ISO Mercury results in decreased expression of SFRP1 mRNA CTD PMID:19937285 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sh3bp2 SH3-domain binding protein 2 increases expression ISO Mercury results in increased expression of SH3BP2 mRNA CTD PMID:19937285 NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251
JBrowse link
G Sh3glb2 SH3 domain-containing GRB2-like endophilin B2 increases expression ISO Mercury results in increased expression of SH3GLB2 mRNA CTD PMID:16823088 NCBI chr 3:13,616,936...13,631,785
Ensembl chr 3:13,616,938...13,631,757
JBrowse link
G Sh3pxd2a SH3 and PX domains 2A increases expression ISO Mercury results in increased expression of SH3PXD2A mRNA CTD PMID:16823088 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166
JBrowse link
G Shc1 SHC adaptor protein 1 decreases expression ISO Mercury results in decreased expression of SHC1 mRNA CTD PMID:16823088 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Sirt5 sirtuin 5 decreases expression ISO Mercury analog results in decreased expression of SIRT5 mRNA CTD PMID:25056781 NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101
JBrowse link
G Slc11a1 solute carrier family 11 member 1 increases expression ISO Mercury results in increased expression of SLC11A1 mRNA CTD PMID:19937285 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression
multiple interactions
increases uptake
ISO Mercury results in decreased expression of SLC11A2 mRNA
[HAMP protein results in decreased expression of SLC11A2 mRNA] which results in decreased uptake of Mercury
SLC11A2 mRNA results in increased uptake of Mercury
SLC11A2 results in increased uptake of Mercury
CTD PMID:25772431 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc12a2 solute carrier family 12 member 2 affects transport EXP SLC12A2 protein mutant form affects the transport of Mercury CTD PMID:12556450 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
JBrowse link
G Slc18a2 solute carrier family 18 member A2 decreases expression ISO Mercury analog results in decreased expression of SLC18A2 mRNA CTD PMID:25056781 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases expression EXP Mercury results in increased expression of SLC22A1 mRNA CTD PMID:12730625 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a19 solute carrier family 22, member 19 multiple interactions
increases expression
EXP EPO protein inhibits the reaction [Mercury results in increased expression of SLC22A19 protein] CTD PMID:32909846 NCBI chr 1:204,910,450...204,965,538
Ensembl chr 1:204,910,455...204,965,538
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Cysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Dithioerythritol inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Mercury binds to and results in decreased activity of SLC22A4 protein CTD PMID:25490951 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
affects response to substance
ISO
EXP
SLC22A6 gene SNP affects the susceptibility to and affects the abundance of Mercury; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury]
SLC22A6 gene SNP affects the susceptibility to Mercury
EPO protein promotes the reaction [Mercury results in increased expression of and affects the localization of SLC22A6 protein]; Mercury results in increased expression of and affects the localization of SLC22A6 protein
CTD PMID:15908511 PMID:23052037 PMID:32909846 PMID:32946573 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO
EXP
[SLC22A8 gene SNP affects the susceptibility to Mercury] which affects the abundance of Mercury; SLC22A8 gene SNP affects the susceptibility to and affects the abundance of Mercury
EPO protein affects the reaction [Mercury affects the localization of SLC22A8 protein]; EPO protein promotes the reaction [Mercury results in increased expression of SLC22A8 protein]; Mercury results in increased expression of and affects the localization of SLC22A8 protein
CTD PMID:23052037 PMID:32909846 PMID:32946573 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc25a22 solute carrier family 25 member 22 decreases expression ISO Mercury results in decreased expression of SLC25A22 mRNA CTD PMID:19937285 NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression EXP Mercury results in decreased expression of SLC2A4 mRNA CTD PMID:22688007 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression EXP Mercury results in increased expression of SLC30A1 mRNA CTD PMID:12730625 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions ISO Mercury inhibits the reaction [SLC39A8 protein results in increased uptake of Cadmium] CTD PMID:16638970 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects import ISO SLC3A2 protein affects the import of Mercury CTD PMID:28786956 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects response to substance ISO SLC6A4 promoter polymorphism affects the susceptibility to Mercury CTD PMID:20526950 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO Mercury results in decreased expression of SLC7A2 mRNA CTD PMID:19937285 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784
JBrowse link
G Slc7a5 solute carrier family 7 member 5 multiple interactions ISO SLC7A5 gene SNP affects the susceptibility to and affects the abundance of Mercury CTD PMID:23052037 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Slit3 slit guidance ligand 3 decreases expression ISO Mercury results in decreased expression of SLIT3 mRNA CTD PMID:16823088 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634
JBrowse link
G Smad2 SMAD family member 2 increases expression ISO Mercury results in increased expression of SMAD2 mRNA CTD PMID:19937285 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO Mercury results in increased expression of SMC4 mRNA CTD PMID:17547211 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Smim14 small integral membrane protein 14 increases expression ISO Mercury results in increased expression of SMIM14 mRNA CTD PMID:16823088 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Mercury results in increased expression of SNRPA mRNA CTD PMID:17547211 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
EXP Mercury results in increased expression of SOD1 mRNA
[Mercury co-treated with Hydrogen Peroxide] results in increased expression of SOD1 mRNA
CTD PMID:23578882 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO Mercury analog results in decreased expression of SOS1 mRNA CTD PMID:25056781 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
JBrowse link
G Sox18 SRY-box transcription factor 18 increases expression ISO Mercury results in increased expression of SOX18 mRNA CTD PMID:16823088 NCBI chr 3:168,785,488...168,787,290
Ensembl chr 3:168,785,490...168,787,290
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP Mercury results in decreased expression of SPINK1 mRNA CTD PMID:22688007 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Mercury results in increased expression of SPP1 mRNA CTD PMID:17547211 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 increases expression ISO Mercury results in increased expression of SPTBN1 mRNA CTD PMID:16823088 NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Srf serum response factor decreases expression ISO Mercury results in decreased expression of SRF mRNA CTD PMID:16823088 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Srpk3 SRSF protein kinase 3 decreases expression ISO Mercury analog results in decreased expression of SRPK3 mRNA CTD PMID:25056781 NCBI chr  X:151,510,452...151,515,208
Ensembl chr  X:151,510,539...151,515,198
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 increases expression ISO Mercury results in increased expression of SRSF2 mRNA CTD PMID:17547211 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338
JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 increases expression ISO Mercury results in increased expression of SRSF7 mRNA CTD PMID:17547211 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965
JBrowse link
G Ssbp1 single stranded DNA binding protein 1 increases expression ISO Mercury results in increased expression of SSBP1 mRNA CTD PMID:19937285 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135
JBrowse link
G Ssr2 signal sequence receptor subunit 2 decreases expression ISO Mercury results in decreased expression of SSR2 mRNA CTD PMID:16823088 NCBI chr 2:174,048,291...174,057,043
Ensembl chr 2:174,048,460...174,057,042
JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression ISO Mercury results in decreased expression of SSTR3 mRNA CTD PMID:19937285 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
JBrowse link
G Stk24 serine/threonine kinase 24 decreases expression ISO Mercury analog results in decreased expression of STK24 mRNA CTD PMID:25056781 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 decreases expression ISO Mercury results in decreased expression of STUB1 mRNA CTD PMID:19937285 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Sub1 SUB1 regulator of transcription decreases expression ISO Mercury results in decreased expression of SUB1 mRNA CTD PMID:19937285 NCBI chr 2:61,005,646...61,020,486
Ensembl chr 2:61,005,666...61,020,436
Ensembl chr 2:61,005,666...61,020,436
JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 affects expression ISO Mercury affects the expression of SZRD1 mRNA CTD PMID:16823088 NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252
JBrowse link
G Tac1 tachykinin, precursor 1 increases expression ISO Mercury results in increased expression of TAC1 mRNA CTD PMID:16823088 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member decreases expression EXP Mercury results in decreased expression of TAP1 mRNA CTD PMID:22688007 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO [methylmercuric chloride results in increased abundance of Mercury] which affects the localization of TARDBP protein CTD PMID:30371865 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tat tyrosine aminotransferase increases activity
multiple interactions
EXP Mercury results in increased activity of TAT protein
Mercury inhibits the reaction [Dexamethasone results in increased activity of TAT protein]
CTD PMID:16307467 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tcf3 transcription factor 3 decreases expression ISO Mercury results in decreased expression of TCF3 mRNA CTD PMID:19937285 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tes testin LIM domain protein decreases expression ISO Mercury results in decreased expression of TES mRNA CTD PMID:22008530 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
JBrowse link
G Tf transferrin increases secretion ISO Mercury results in increased secretion of TF protein CTD PMID:10798623 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression ISO Mercury results in increased expression of TGFB2 mRNA CTD PMID:16823088 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Them6 thioesterase superfamily member 6 decreases expression ISO Mercury analog results in decreased expression of THEM6 mRNA CTD PMID:25056781 NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746
JBrowse link
G Thumpd2 THUMP domain containing 2 decreases expression ISO Mercury analog results in decreased expression of THUMPD2 mRNA CTD PMID:25056781 NCBI chr 6:13,924,742...13,976,657
Ensembl chr 6:13,924,765...13,976,657
JBrowse link
G Thumpd3 THUMP domain containing 3 decreases expression ISO Mercury results in decreased expression of THUMPD3 mRNA CTD PMID:22008530 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246
JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 decreases expression EXP Mercury results in decreased expression of TIMM13 mRNA CTD PMID:22688007 NCBI chr 7:8,809,069...8,810,172
Ensembl chr 7:8,809,058...8,809,910
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 increases expression EXP Mercury results in increased expression of TIMM23 mRNA CTD PMID:22688007 NCBI chr16:7,410,308...7,436,392
Ensembl chr16:7,409,688...7,436,379
Ensembl chr 3:7,409,688...7,436,379
Ensembl chr 6:7,409,688...7,436,379
JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO Mercury results in decreased expression of TJP1 mRNA CTD PMID:37137463 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tk2 thymidine kinase 2 affects expression ISO Mercury affects the expression of TK2 mRNA CTD PMID:16823088 NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924
JBrowse link
G Tm2d1 TM2 domain containing 1 increases expression ISO Mercury results in increased expression of TM2D1 mRNA CTD PMID:16823088 NCBI chr 5:113,020,793...113,062,134
Ensembl chr 5:113,020,760...113,050,933
JBrowse link
G Tmf1 TATA element modulatory factor 1 decreases expression ISO Mercury results in decreased expression of TMF1 mRNA CTD PMID:16823088 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
affects expression
EXP
ISO
Mercury results in increased expression of TNF mRNA
Mercury promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Mercury results in increased expression of TNF protein
Mercury affects the expression of TNF mRNA
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese] results in increased expression of TNF protein; [Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein]; Mercury inhibits the reaction [TNF protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein]; Zinc inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of TNF protein]
[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA; CASP1 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of TNF mRNA]
Mercury results in increased expression of TNF mRNA; Mercury results in increased expression of TNF protein
CTD PMID:12730625 PMID:12928768 PMID:15282405 PMID:20176347 PMID:20600710 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Mercury results in increased expression of TNFAIP3 mRNA CTD PMID:17547211 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression
decreases expression
ISO
EXP
Mercury results in increased expression of TNFAIP8 mRNA
Mercury results in decreased expression of TNFAIP8 mRNA
CTD PMID:17547211 PMID:22688007 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP Mercury results in increased expression of TNFRSF1A mRNA; Mercury results in increased expression of TNFRSF1A protein CTD PMID:12730625 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Mercury results in decreased expression of TNFSF10 mRNA CTD PMID:17547211 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tns2 tensin 2 decreases expression ISO Mercury analog results in decreased expression of TNS2 mRNA CTD PMID:25056781 NCBI chr 7:133,229,746...133,247,889
Ensembl chr 7:133,206,364...133,247,888
JBrowse link
G Tox3 TOX high mobility group box family member 3 increases expression ISO Mercury results in increased expression of TOX3 mRNA CTD PMID:16823088 NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148
JBrowse link
G Tp53 tumor protein p53 affects folding ISO Mercury affects the folding of TRP53 protein CTD PMID:8467489 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm2 tropomyosin 2 increases expression ISO Mercury results in increased expression of TPM2 mRNA CTD PMID:16823088 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992
JBrowse link
G Tradd TNFRSF1A-associated via death domain increases expression EXP Mercury results in increased expression of TRADD protein CTD PMID:12730625 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Mercury results in decreased expression of TRIB3 mRNA CTD PMID:19937285 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO Mercury results in increased expression of TRIP13 mRNA CTD PMID:17547211 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
JBrowse link
G Tspan7 tetraspanin 7 decreases expression ISO Mercury results in decreased expression of TSPAN7 mRNA CTD PMID:17547211 NCBI chr  X:12,208,783...12,306,092
Ensembl chr  X:12,208,783...12,306,131
JBrowse link
G Tst thiosulfate sulfurtransferase decreases expression ISO Mercury results in decreased expression of TST mRNA CTD PMID:17547211 NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216
JBrowse link
G Tuba8 tubulin, alpha 8 decreases expression ISO Mercury analog results in decreased expression of TUBA8 mRNA CTD PMID:25056781 NCBI chr 4:154,440,045...154,456,918
Ensembl chr 4:154,440,074...154,456,917
JBrowse link
G Twf2 twinfilin actin-binding protein 2 decreases expression ISO Mercury results in decreased expression of TWF2 mRNA CTD PMID:16823088 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Txn1 thioredoxin 1 affects binding ISO Mercury binds to TXN protein CTD PMID:18321861 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txndc11 thioredoxin domain containing 11 decreases expression ISO Mercury analog results in decreased expression of TXNDC11 mRNA CTD PMID:25056781 NCBI chr10:4,515,457...4,572,999
Ensembl chr10:4,515,478...4,572,989
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Mercury results in increased expression of TXNRD1 mRNA CTD PMID:17547211 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 decreases activity EXP Mercury results in decreased activity of TXNRD2 protein CTD PMID:17157198 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Tyms thymidylate synthetase increases expression ISO Mercury results in increased expression of TYMS mRNA CTD PMID:17547211 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression ISO Mercury results in increased expression of UBE2C mRNA CTD PMID:17547211 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 decreases expression ISO Mercury analog results in decreased expression of UBE2L3 mRNA CTD PMID:25056781 NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N decreases expression ISO Mercury results in decreased expression of UBE2N mRNA CTD PMID:16823088 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO Mercury results in increased expression of UGCG mRNA CTD PMID:17547211 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein increases expression ISO Mercury results in increased expression of UQCRB mRNA CTD PMID:16823088 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
JBrowse link
G Urod uroporphyrinogen decarboxylase decreases activity ISO Mercury results in decreased activity of UROD protein CTD PMID:15967199 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808
JBrowse link
G Usp39 ubiquitin specific peptidase 39 increases expression ISO Mercury results in increased expression of USP39 mRNA CTD PMID:16823088 NCBI chr 4:104,373,948...104,406,359
Ensembl chr 4:104,373,955...104,406,359
JBrowse link
G Usp53 ubiquitin specific peptidase 53 decreases expression ISO Mercury analog results in decreased expression of USP53 mRNA CTD PMID:25056781 NCBI chr 2:211,059,512...211,120,942
Ensembl chr 2:211,059,520...211,120,943
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 increases expression ISO Mercury results in increased expression of USPL1 mRNA CTD PMID:16823088 NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein decreases expression ISO Mercury analog results in decreased expression of VASP mRNA CTD PMID:25056781 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vdr vitamin D receptor affects abundance ISO VDR gene polymorphism affects the abundance of Mercury CTD PMID:25728017 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vim vimentin increases expression ISO Mercury results in increased expression of VIM mRNA CTD PMID:26600472 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vps36 vacuolar protein sorting 36 homolog decreases expression ISO Mercury analog results in decreased expression of VPS36 mRNA CTD PMID:25056781 NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810
JBrowse link
G Vtn vitronectin decreases expression ISO Mercury results in decreased expression of VTN mRNA CTD PMID:17547211 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 increases expression ISO Mercury results in increased expression of VWA1 mRNA CTD PMID:16823088 NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637
JBrowse link
G Wdr12 WD repeat domain 12 decreases expression EXP Mercury results in decreased expression of WDR12 mRNA CTD PMID:22688007 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 decreases expression ISO Mercury results in decreased expression of WIPI1 mRNA CTD PMID:22008530 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Xist X inactive specific transcript increases expression ISO Mercury results in increased expression of XIST mRNA CTD PMID:22008530 NCBI chr  X:68,474,987...68,492,500 JBrowse link
G Ybx1 Y box binding protein 1 increases expression ISO Mercury results in increased expression of YBX1 mRNA CTD PMID:16823088 NCBI chr 5:132,882,137...132,898,885
Ensembl chr 5:132,882,145...132,898,862
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta decreases expression ISO Mercury analog results in decreased expression of YWHAQ mRNA CTD PMID:25056781 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta decreases expression ISO Mercury results in decreased expression of YWHAZ mRNA CTD PMID:16823088 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO Mercury results in increased expression of ZBTB1 mRNA CTD PMID:16823088 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO Mercury results in increased expression of ZBTB10 mRNA CTD PMID:16823088 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 increases expression ISO Mercury results in increased expression of ZBTB16 mRNA CTD PMID:19937285 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zbtb38 zinc finger and BTB domain containing 38 increases expression ISO Mercury results in increased expression of ZBTB38 mRNA CTD PMID:19937285 NCBI chr 8:97,284,617...97,288,518
Ensembl chr 8:97,280,993...97,485,625
JBrowse link
G Zfand3 zinc finger AN1-type containing 3 decreases expression ISO Mercury analog results in decreased expression of ZFAND3 mRNA CTD PMID:25056781 NCBI chr20:8,083,407...8,279,617
Ensembl chr20:8,082,200...8,279,616
JBrowse link
G Zfhx4 zinc finger homeobox 4 decreases expression ISO Mercury analog results in decreased expression of ZFHX4 mRNA CTD PMID:25056781 NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228
JBrowse link
G Zfp174 zinc finger protein 174 decreases expression ISO Mercury results in decreased expression of ZNF174 mRNA CTD PMID:19937285 NCBI chr10:11,666,580...11,676,328
Ensembl chr10:11,669,913...11,676,312
JBrowse link
G Zfp866 zinc finger protein 866 increases expression EXP Mercury results in increased expression of CXCL5 mRNA CTD PMID:12730625 NCBI chr16:19,653,966...19,675,968
Ensembl chr16:19,668,258...19,675,932
JBrowse link
G Zfp950 zinc finger protein 950 increases expression ISO Mercury results in increased expression of ZNF80 mRNA CTD PMID:16823088 NCBI chr 1:260,248,231...260,265,211
Ensembl chr 1:260,236,599...260,265,254
JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Mercury results in increased expression of ZWINT mRNA CTD PMID:17547211 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      molecular entity 19878
        transition element molecular entity 17439
          d-block molecular entity 17438
            zinc group molecular entity 13154
              mercury molecular entity 6773
                elemental mercury 567
                  mercury cation + 0
                  mercury(0) 567
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  metal atom 18032
                    transition element atom 17576
                      d-block element atom 17571
                        d-block molecular entity 17438
                          zinc group molecular entity 13154
                            mercury molecular entity 6773
                              elemental mercury 567
                                mercury cation + 0
                                mercury(0) 567
paths to the root