CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: fentin chloride
Accession: CHEBI:35036
browse the term
Definition: An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a chloro group. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans.
Synonyms: related_synonym: Chlorotriphenylstannane; Chlorotriphenyltin; Formula=C18H15ClSn; InChI=1S/3C6H5.ClH.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H;/q;;;;+1/p-1; InChIKey=NJVOZLGKTAPUTQ-UHFFFAOYSA-M; SMILES=Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1; TPTC; Triphenylchlorostannane; Triphenylchlorotin; Triphenyltin chloride; triphenylstannylium chloride
xref: CAS:639-58-7; KEGG:C14413; LINCS:LSM-37196
xref_mesh: MESH:C012594
xref: PMID:1280083; PMID:1677872; PMID:19882143; PMID:20591183; PMID:20708649; PMID:2084225; PMID:22002760; PMID:23128992; PMID:23981671; PMID:25045140; PMID:7679203; PPDB:1477; Reaxys:524762
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Abca1
ATP binding cassette subfamily A member 1
multiple interactions
ISO
[triphenyltin chloride results in increased abundance of triphenyltin] which results in increased expression of ABCA1 mRNA
CTD
PMID:35998708
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcc3
ATP binding cassette subfamily C member 3
increases expression
EXP
triphenyltin chloride results in increased expression of ABCC3 mRNA
CTD
PMID:37156404
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcg3l4
ATP-binding cassette, subfamily G (WHITE), member 3-like 4
increases expression
EXP
triphenyltin chloride results in increased expression of ABCG3L4 mRNA
CTD
PMID:37156404
NCBI chr14:4,545,206...4,590,223
Ensembl chr14:4,545,223...4,585,347
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Acsl1
acyl-CoA synthetase long-chain family member 1
increases expression
EXP
triphenyltin chloride results in increased expression of ACSL1 mRNA
CTD
PMID:37156404
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsm2
acyl-CoA synthetase medium-chain family member 2
increases expression
EXP
triphenyltin chloride results in increased expression of ACSM2 mRNA
CTD
PMID:37156404
NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
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Acsm5
acyl-CoA synthetase medium-chain family member 5
increases expression
EXP
triphenyltin chloride results in increased expression of ACSM5 mRNA
CTD
PMID:37156404
NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions increases expression
ISO
[triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] affects the expression of ADIPOQ protein; triphenyltin chloride inhibits the reaction [Dexamethasone results in increased expression of ADIPOQ protein]; triphenyltin chloride inhibits the reaction [Rosiglitazone results in increased expression of ADIPOQ protein] triphenyltin chloride results in increased expression of ADIPOQ protein
CTD
PMID:37142754
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
increases expression
EXP
triphenyltin chloride results in increased expression of ALDH1A1 mRNA
CTD
PMID:37156404
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh1l2
aldehyde dehydrogenase 1 family, member L2
decreases expression
EXP
triphenyltin chloride results in decreased expression of ALDH1L2 mRNA
CTD
PMID:37156404
NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
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Anxa5
annexin A5
decreases expression multiple interactions
ISO
triphenyltin chloride results in decreased expression of ANXA5 protein Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of ANXA5 protein]
CTD
PMID:30806631
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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Apcdd1
APC down-regulated 1
increases expression
EXP
triphenyltin chloride results in increased expression of APCDD1 mRNA
CTD
PMID:37156404
NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070
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Ar
androgen receptor
multiple interactions
ISO
triphenyltin chloride inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
CTD
PMID:33049310
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arhgef19
Rho guanine nucleotide exchange factor 19
decreases expression
EXP
triphenyltin chloride results in decreased expression of ARHGEF19 mRNA
CTD
PMID:37156404
NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203
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Arrdc3
arrestin domain containing 3
increases expression
EXP
triphenyltin chloride results in increased expression of ARRDC3 mRNA
CTD
PMID:37156404
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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Atp8b3
ATPase phospholipid transporting 8B3
decreases expression
EXP
triphenyltin chloride results in decreased expression of ATP8B3 mRNA
CTD
PMID:37156404
NCBI chr 7:9,175,544...9,195,449
Ensembl chr 7:9,175,391...9,195,442
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Bhmt
betaine-homocysteine S-methyltransferase
decreases expression
EXP
triphenyltin chloride results in decreased expression of BHMT mRNA
CTD
PMID:37156404
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Btg2
BTG anti-proliferation factor 2
increases expression
EXP
triphenyltin chloride results in increased expression of BTG2 mRNA
CTD
PMID:37156404
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Cers6
ceramide synthase 6
increases expression
EXP
triphenyltin chloride results in increased expression of CERS6 mRNA
CTD
PMID:37156404
NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
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Ces2c
carboxylesterase 2C
increases expression
EXP
triphenyltin chloride results in increased expression of CES2C mRNA
CTD
PMID:37156404
NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
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Cldn1
claudin 1
decreases expression
EXP
triphenyltin chloride results in decreased expression of CLDN1 mRNA
CTD
PMID:37156404
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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Crebrf
CREB3 regulatory factor
increases expression
EXP
triphenyltin chloride results in increased expression of CREBRF mRNA
CTD
PMID:37156404
NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
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Crot
carnitine O-octanoyltransferase
decreases expression
EXP
triphenyltin chloride results in decreased expression of CROT mRNA
CTD
PMID:37156404
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases expression
ISO
triphenyltin chloride results in increased expression of CYP19A1 mRNA
CTD
PMID:15941851
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Cyp2c6-ps2
cytochrome P450, family 2, subfamily C, polypeptide 6, pseudogene 2
increases expression
EXP
triphenyltin chloride results in increased expression of CYP2C6_V1-PS2 mRNA
CTD
PMID:37156404
NCBI chr 1:238,352,261...238,391,716
Ensembl chr 1:238,352,131...238,504,300
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
EXP
triphenyltin chloride results in increased expression of CYP2E1 mRNA
CTD
PMID:37156404
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Dusp6
dual specificity phosphatase 6
increases expression
EXP
triphenyltin chloride results in increased expression of DUSP6 mRNA
CTD
PMID:37156404
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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Egr1
early growth response 1
increases expression
EXP
triphenyltin chloride results in increased expression of EGR1 mRNA
CTD
PMID:37156404
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases expression
EXP
triphenyltin chloride results in increased expression of EIF2AK3 protein
CTD
PMID:37156404
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Elovl5
ELOVL fatty acid elongase 5
decreases expression increases expression
EXP
triphenyltin chloride results in decreased expression of ELOVL5 mRNA triphenyltin chloride results in increased expression of ELOVL5 mRNA
CTD
PMID:37156404
NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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Ern1
endoplasmic reticulum to nucleus signaling 1
increases expression
EXP
triphenyltin chloride results in increased expression of ERN1 protein
CTD
PMID:37156404
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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Esr2
estrogen receptor 2
multiple interactions
ISO
triphenyltin chloride binds to and results in decreased activity of ESR2 protein
CTD
PMID:33049310
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fabp4
fatty acid binding protein 4
multiple interactions increases expression
ISO
[triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] results in increased expression of FABP4 protein; triphenyltin chloride affects the reaction [tributyltin results in increased expression of FABP4 protein]; triphenyltin chloride promotes the reaction [Dexamethasone results in increased expression of FABP4 protein]; triphenyltin chloride promotes the reaction [Rosiglitazone results in increased expression of FABP4 protein] triphenyltin chloride results in increased expression of FABP4 protein
CTD
PMID:37142754
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fmo1
flavin containing dimethylaniline monoxygenase 1
increases expression
EXP
triphenyltin chloride results in increased expression of FMO1 mRNA
CTD
PMID:37156404
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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Foxa2
forkhead box A2
increases expression
EXP
triphenyltin chloride results in increased expression of FOXA2 mRNA
CTD
PMID:37156404
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
EXP
triphenyltin chloride results in increased expression of GADD45B mRNA
CTD
PMID:37156404
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
decreases expression multiple interactions
ISO
triphenyltin chloride results in decreased expression of GAPDH protein triphenyltin chloride promotes the reaction [Tretinoin results in decreased expression of GAPDH protein]
CTD
PMID:30806631
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Gcnt2
glucosaminyl (N-acetyl) transferase 2
increases expression
EXP
triphenyltin chloride results in increased expression of GCNT2 mRNA
CTD
PMID:37156404
NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
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Gldc
glycine decarboxylase
decreases expression
EXP
triphenyltin chloride results in decreased expression of GLDC mRNA
CTD
PMID:37156404
NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097
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Glt1d1
glycosyltransferase 1 domain containing 1
increases expression
EXP
triphenyltin chloride results in increased expression of GLT1D1 mRNA
CTD
PMID:37156404
NCBI chr12:28,975,984...29,049,707
Ensembl chr12:28,975,988...29,049,695
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Glul
glutamate-ammonia ligase
increases expression
EXP
triphenyltin chloride results in increased expression of GLUL mRNA
CTD
PMID:37156404
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
decreases expression
EXP
triphenyltin chloride results in decreased expression of GPAM mRNA
CTD
PMID:37156404
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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H1f2
H1.2 linker histone, cluster member
increases expression
EXP
triphenyltin chloride results in increased expression of H1F2 mRNA
CTD
PMID:37156404
NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
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Hat1
histone acetyltransferase 1
increases activity
EXP
triphenyltin chloride results in increased activity of HAT1 protein
CTD
PMID:15603928
NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
EXP
triphenyltin chloride results in increased expression of HMGCR mRNA
CTD
PMID:37156404
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
EXP
triphenyltin chloride results in increased expression of HMGCS1 mRNA
CTD
PMID:37156404
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
multiple interactions increases expression
ISO
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]; Cycloheximide promotes the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein
CTD
PMID:31927052
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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Hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
increases expression increases activity
ISO
triphenyltin chloride results in increased expression of HSD17B1 mRNA triphenyltin chloride results in increased activity of HSD17B1 protein
CTD
PMID:16513093
NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927
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Hspb1
heat shock protein family B (small) member 1
increases expression
EXP
triphenyltin chloride results in increased expression of HSPB1 mRNA
CTD
PMID:37156404
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Ier2
immediate early response 2
increases expression
EXP
triphenyltin chloride results in increased expression of IER2 mRNA
CTD
PMID:37156404
NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
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Igfbp1
insulin-like growth factor binding protein 1
increases expression
EXP
triphenyltin chloride results in increased expression of IGFBP1 mRNA
CTD
PMID:37156404
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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Igfbp2
insulin-like growth factor binding protein 2
increases expression
EXP
triphenyltin chloride results in increased expression of IGFBP2 mRNA
CTD
PMID:37156404
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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Il1b
interleukin 1 beta
multiple interactions
ISO
Lipopolysaccharides promotes the reaction [triphenyltin chloride results in increased expression of IL1B mRNA]
CTD
PMID:16687389
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions
ISO
Lipopolysaccharides promotes the reaction [triphenyltin chloride results in increased expression of IL6 mRNA]
CTD
PMID:16687389
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Inhbc
inhibin subunit beta C
decreases expression
EXP
triphenyltin chloride results in decreased expression of INHBC mRNA
CTD
PMID:37156404
NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
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Inhbe
inhibin subunit beta E
decreases expression
EXP
triphenyltin chloride results in decreased expression of INHBE mRNA
CTD
PMID:37156404
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
triphenyltin chloride results in increased expression of JUN mRNA
CTD
PMID:37156404
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kcnj15
potassium inwardly-rectifying channel, subfamily J, member 15
increases expression
EXP
triphenyltin chloride results in increased expression of KCNJ15 mRNA
CTD
PMID:37156404
NCBI chr11:34,577,397...34,621,725
Ensembl chr11:34,577,363...34,621,952
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Klrg1
killer cell lectin like receptor G1
decreases expression
EXP
triphenyltin chloride results in decreased expression of KLRG1 mRNA
CTD
PMID:37156404
NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424
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Ldha
lactate dehydrogenase A
decreases expression
EXP
triphenyltin chloride results in decreased expression of LDHA mRNA
CTD
PMID:37156404
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Leap2
liver enriched antimicrobial peptide 2
decreases expression
EXP
triphenyltin chloride results in decreased expression of LEAP2 mRNA
CTD
PMID:37156404
NCBI chr10:37,580,172...37,581,244
Ensembl chr10:37,577,855...37,581,244
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Lepr
leptin receptor
increases expression
EXP
triphenyltin chloride results in increased expression of LEPR mRNA
CTD
PMID:37156404
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Ly75
lymphocyte antigen 75
increases expression
EXP
triphenyltin chloride results in increased expression of LY75 mRNA
CTD
PMID:37156404
NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
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Meox2
mesenchyme homeobox 2
increases expression
EXP
triphenyltin chloride results in increased expression of MEOX2 mRNA
CTD
PMID:37156404
NCBI chr 6:53,856,760...53,917,467
Ensembl chr 6:53,856,758...53,917,467
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Mmp8
matrix metallopeptidase 8
increases expression
EXP
triphenyltin chloride results in increased expression of MMP8 mRNA
CTD
PMID:37156404
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
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Mt1
metallothionein 1
increases expression
EXP
triphenyltin chloride results in increased expression of MT1 mRNA
CTD
PMID:37156404
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A
metallothionein 2A
increases expression
EXP
triphenyltin chloride results in increased expression of MT2A mRNA
CTD
PMID:37156404
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mthfr
methylenetetrahydrofolate reductase
decreases expression
EXP
triphenyltin chloride results in decreased expression of MTHFR mRNA
CTD
PMID:37156404
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mybl1
MYB proto-oncogene like 1
decreases expression
EXP
triphenyltin chloride results in decreased expression of MYBL1 mRNA
CTD
PMID:37156404
NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
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Net1
neuroepithelial cell transforming 1
increases expression
EXP
triphenyltin chloride results in increased expression of NET1 mRNA
CTD
PMID:37156404
NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
multiple interactions decreases expression
ISO
Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of NME2 protein]
CTD
PMID:30806631
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
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Noct
nocturnin
decreases expression
EXP
triphenyltin chloride results in decreased expression of NOCT mRNA
CTD
PMID:37156404
NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
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Npnt
nephronectin
decreases expression
EXP
triphenyltin chloride results in decreased expression of NPNT mRNA
CTD
PMID:37156404
NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
triphenyltin chloride binds to and results in decreased activity of NR1I2 protein triphenyltin chloride binds to and results in increased activity of NR1I2 protein
CTD
PMID:33049310
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Ogfrl1
opioid growth factor receptor-like 1
increases expression
EXP
triphenyltin chloride results in increased expression of OGFRL1 mRNA
CTD
PMID:37156404
NCBI chr 9:25,828,865...25,842,424
Ensembl chr 9:25,828,869...25,842,352
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Osgin1
oxidative stress induced growth inhibitor 1
increases expression
EXP
triphenyltin chloride results in increased expression of OSGIN1 mRNA
CTD
PMID:37156404
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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Pla2g15
phospholipase A2, group XV
increases expression
EXP
triphenyltin chloride results in increased expression of PLA2G15 mRNA
CTD
PMID:37156404
NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
EXP
triphenyltin chloride results in increased expression of and affects the localization of PPARA protein
CTD
PMID:37156404
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions increases activity increases expression
ISO EXP
diphenyltin chloride inhibits the reaction [triphenyltin chloride binds to PPARG protein]; tetrabutyltin inhibits the reaction [triphenyltin chloride binds to PPARG protein]; tributyltin inhibits the reaction [triphenyltin chloride binds to PPARG protein]; triphenyltin chloride binds to and results in increased activity of PPARG protein; triphenyltin chloride inhibits the reaction [Rosiglitazone binds to PPARG protein] triphenyltin chloride results in increased activity of PPARG protein [triphenyltin chloride co-treated with tributyltin co-treated with dibutyldichlorotin] results in increased expression of PPARG protein; triphenyltin chloride binds to and results in increased activity of PPARG protein; triphenyltin chloride inhibits the reaction [Dexamethasone results in increased expression of PPARG protein]; triphenyltin chloride inhibits the reaction [Rosiglitazone results in increased expression of PPARG protein] triphenyltin chloride results in increased expression of PPARG protein triphenyltin chloride results in increased expression of and affects the localization of PPARG protein
CTD
PMID:19497422 PMID:26172262 PMID:33049310 PMID:37142754 PMID:37156404
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Reg4
regenerating family member 4
decreases expression
EXP
triphenyltin chloride results in decreased expression of REG4 mRNA
CTD
PMID:37156404
NCBI chr 2:185,818,946...185,833,252
Ensembl chr 2:185,821,210...185,833,353
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Rgs16
regulator of G-protein signaling 16
increases expression
EXP
triphenyltin chloride results in increased expression of RGS16 mRNA
CTD
PMID:37156404
NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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Rxra
retinoid X receptor alpha
multiple interactions increases expression
ISO EXP
RXRA protein affects the reaction [triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; triphenyltin chloride inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein] triphenyltin chloride results in increased expression of RXRA protein
CTD
PMID:15941851 PMID:31927052 PMID:37156404
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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S1pr1
sphingosine-1-phosphate receptor 1
decreases expression
EXP
triphenyltin chloride results in decreased expression of S1PR1 mRNA
CTD
PMID:37156404
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
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Scd
stearoyl-CoA desaturase
decreases expression
EXP
triphenyltin chloride results in decreased expression of SCD mRNA
CTD
PMID:37156404
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Serpina7
serpin family A member 7
increases expression
EXP
triphenyltin chloride results in increased expression of SERPINA7 mRNA
CTD
PMID:37156404
NCBI chr X:102,663,242...102,722,319
Ensembl chr X:102,663,405...102,669,040
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Sigmar1
sigma non-opioid intracellular receptor 1
decreases expression
EXP
triphenyltin chloride results in decreased expression of SIGMAR1 mRNA
CTD
PMID:37156404
NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017
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Slc16a10
solute carrier family 16 member 10
increases expression
EXP
triphenyltin chloride results in increased expression of SLC16A10 mRNA
CTD
PMID:37156404
NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
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Slc1a2
solute carrier family 1 member 2
increases expression
EXP
triphenyltin chloride results in increased expression of SLC1A2 mRNA
CTD
PMID:37156404
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
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Slc34a2
solute carrier family 34 member 2
decreases expression
EXP
triphenyltin chloride results in decreased expression of SLC34A2 mRNA
CTD
PMID:37156404
NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
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Slpi
secretory leukocyte peptidase inhibitor
increases expression
EXP
triphenyltin chloride results in increased expression of SLPI mRNA
CTD
PMID:37156404
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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Sparcl1
SPARC like 1
increases expression
EXP
triphenyltin chloride results in increased expression of SPARCL1 mRNA
CTD
PMID:37156404
NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
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Spink1
serine peptidase inhibitor, Kazal type 1
increases expression
EXP
triphenyltin chloride results in increased expression of SPINK1 mRNA
CTD
PMID:37156404
NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
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Srebf1
sterol regulatory element binding transcription factor 1
multiple interactions decreases expression
ISO EXP
[triphenyltin chloride results in increased abundance of triphenyltin] which results in increased expression of SREBF1 mRNA triphenyltin chloride results in decreased expression of SREBF1 mRNA
CTD
PMID:35998708 PMID:37156404
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Sstr3
somatostatin receptor 3
decreases expression
EXP
triphenyltin chloride results in decreased expression of SSTR3 mRNA
CTD
PMID:37156404
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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St6galnac4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
decreases expression
EXP
triphenyltin chloride results in decreased expression of ST6GALNAC4 mRNA
CTD
PMID:37156404
NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
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Thrb
thyroid hormone receptor beta
multiple interactions
ISO
triphenyltin chloride binds to and results in increased activity of THRB protein
CTD
PMID:33049310
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
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Tnf
tumor necrosis factor
increases secretion
ISO
triphenyltin chloride results in increased secretion of TNF protein
CTD
PMID:8660944
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tor3a
torsin family 3, member A
decreases expression
EXP
triphenyltin chloride results in decreased expression of TOR3A mRNA
CTD
PMID:37156404
NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475
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Trib1
tribbles pseudokinase 1
increases expression
EXP
triphenyltin chloride results in increased expression of TRIB1 mRNA
CTD
PMID:37156404
NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
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Ttr
transthyretin
decreases expression
EXP
triphenyltin chloride results in decreased expression of TTR mRNA
CTD
PMID:37156404
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Txnip
thioredoxin interacting protein
increases expression
EXP
triphenyltin chloride results in increased expression of TXNIP mRNA
CTD
PMID:37156404
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Upb1
beta-ureidopropionase 1
decreases expression
EXP
triphenyltin chloride results in decreased expression of UPB1 mRNA
CTD
PMID:37156404
NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590
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Upp2
uridine phosphorylase 2
increases expression
EXP
triphenyltin chloride results in increased expression of UPP2 mRNA
CTD
PMID:37156404
NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
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Vim
vimentin
decreases expression multiple interactions
ISO
triphenyltin chloride results in decreased expression of VIM protein [Tretinoin co-treated with triphenyltin chloride] results in decreased expression of VIM mRNA; Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of VIM protein]
CTD
PMID:30806631 PMID:31634547
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vxn
vexin
decreases expression
EXP
triphenyltin chloride results in decreased expression of VXN mRNA
CTD
PMID:37156404
NCBI chr 5:9,659,213...9,684,684
Ensembl chr 5:9,659,213...9,684,684
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Wfdc2
WAP four-disulfide core domain 2
increases expression
EXP
triphenyltin chloride results in increased expression of WFDC2 mRNA
CTD
PMID:37156404
NCBI chr 3:153,286,946...153,314,832
Ensembl chr 3:153,286,131...153,292,807
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Xbp1
X-box binding protein 1
increases expression
EXP
triphenyltin chloride results in increased expression of XBP1 mRNA
CTD
PMID:37156404
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Ybx2
Y box binding protein 2
decreases expression
EXP
triphenyltin chloride results in decreased expression of YBX2 mRNA
CTD
PMID:37156404
NCBI chr10:54,659,719...54,665,371
Ensembl chr10:54,659,719...54,665,371
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Zfp622
zinc finger protein 622
increases expression
EXP
triphenyltin chloride results in increased expression of ZFP622 mRNA
CTD
PMID:37156404
NCBI chr 2:76,479,605...76,494,405
Ensembl chr 2:76,335,609...76,493,898
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