CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: rimonabant
Accession: CHEBI:34967
browse the term
Definition: A carbohydrazide obtained by formal condensation of the carboxy group of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. It is a potent and selective cannabinoid receptor 1 (CB1R) antagonist. Besides its antagonistic properties, numerous studies have shown that, at micromolar concentrations rimonabant behaves as an inverse agonist at CB1 receptors. The drug was the first selective CB1 antagonist/inverse agonist introduced into clinical practice to treat obesity and metabolic-related disorders. It was later withdrawn from market due to CNS-related adverse effects including depression and suicidal ideation.
Synonyms: exact_synonym: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
related_synonym: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; A 281; Formula=C22H21Cl3N4O; InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30); InChIKey=JZCPYUJPEARBJL-UHFFFAOYSA-N; SMILES=CC1=C(N(N=C1C(=O)NN1CCCCC1)C1=CC=C(Cl)C=C1Cl)C1=CC=C(Cl)C=C1; SR 141716; SR141716; Zimulti; acomplia; rimonabantum
xref: CAS:168273-06-1; Chemspider:94641; DrugBank:DB06155; Drug_Central:4150; HMDB:HMDB0015623; KEGG:C14319; KEGG:D05731; KNApSAcK:C00053749; LINCS:LSM-36994
xref_mesh: MESH:D000077285
xref: PDBeChem:AY6; PMID:11881536; PMID:16934319; PMID:18290515; PMID:18479080; PMID:18654765; PMID:19490094; PMID:20067470; PMID:20828968; PMID:21470203; PMID:21740450; PMID:22182934; PMID:28429843; PMID:29407764; PMID:29797785; PMID:30077950; PMID:30300803; PMID:30556096; PMID:30682372; PMID:31522677; PMID:31898189; PMID:31981244; PMID:32085406; PMID:32417279; PMID:32463562; PMID:32512776; PMID:32781169; PMID:32885412; PMID:32904155; PMID:33121353; Wikipedia:Rimonabant
G
Acaca
acetyl-CoA carboxylase alpha
affects expression
ISO
Rimonabant affects the expression of ACACA mRNA
CTD
PMID:20110567
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
G
Acacb
acetyl-CoA carboxylase beta
increases expression
ISO
Rimonabant results in increased expression of ACACB mRNA
CTD
PMID:20110567
NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
G
Acadm
acyl-CoA dehydrogenase medium chain
affects expression multiple interactions
ISO
Rimonabant affects the expression of ACADM mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACADM mRNA]
CTD
PMID:19030233
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
G
Acbd5
acyl-CoA binding domain containing 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACBD5 mRNA]
CTD
PMID:19030233
NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
G
Acta2
actin alpha 2, smooth muscle
decreases expression
EXP
Rimonabant results in decreased expression of ACTA2 mRNA
CTD
PMID:21863215
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
G
Actr2
actin related protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ACTR2 mRNA]
CTD
PMID:19030233
NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
G
Adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ADAMTS1 mRNA]
CTD
PMID:19030233
NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
G
Adgre1
adhesion G protein-coupled receptor E1
decreases expression
EXP
Rimonabant results in decreased expression of ADGRE1 mRNA
CTD
PMID:30365523
NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
G
Adipoq
adiponectin, C1Q and collagen domain containing
increases expression
ISO
Rimonabant results in increased expression of ADIPOQ mRNA; Rimonabant results in increased expression of ADIPOQ protein
CTD
PMID:16282221 PMID:20110567
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
G
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
multiple interactions increases expression
ISO
Rimonabant inhibits the reaction [MIR762 mRNA results in decreased expression of AGAP2 mRNA]; Rimonabant promotes the reaction [Dietary Fats results in increased expression of AGAP2 mRNA] Rimonabant results in increased expression of AGAP2 mRNA
CTD
PMID:30910812
NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
G
Akt1
AKT serine/threonine kinase 1
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of AKT1 protein] Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of AKT1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of AKT1 protein]
CTD
PMID:12834810 PMID:31917333
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Alkbh1
alkB homolog 1, histone H2A dioxygenase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ALKBH1 mRNA]
CTD
PMID:19030233
NCBI chr 6:107,068,301...107,088,784
Ensembl chr 6:107,068,475...107,088,759
G
Anxa1
annexin A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA1 mRNA]
CTD
PMID:19030233
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
G
Anxa2
annexin A2
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ANXA2 mRNA] Rimonabant affects the expression of ANXA2 mRNA
CTD
PMID:19030233
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
G
Apob
apolipoprotein B
increases secretion
ISO
Rimonabant results in increased secretion of APOB protein
CTD
PMID:20110567
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
G
App
amyloid beta precursor protein
affects expression multiple interactions
ISO
Rimonabant affects the expression of APP mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of APP mRNA]
CTD
PMID:19030233
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
G
Arg1
arginase 1
multiple interactions
ISO
Rimonabant promotes the reaction [Dietary Fats results in increased expression of ARG1]
CTD
PMID:30910812
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
G
Arhgef12
Rho guanine nucleotide exchange factor 12
affects expression multiple interactions
ISO
Rimonabant affects the expression of ARHGEF12 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARHGEF12 mRNA]
CTD
PMID:19030233
NCBI chr 8:43,350,070...43,475,404
Ensembl chr 8:43,353,799...43,476,366
G
Arpp19
cAMP-regulated phosphoprotein 19
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ARPP19 mRNA]
CTD
PMID:19030233
NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452 Ensembl chr 8:75,779,523...75,802,452
G
Arrb2
arrestin, beta 2
multiple interactions
ISO
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]
CTD
PMID:27779402
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
G
Atf4
activating transcription factor 4
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF4 mRNA]
CTD
PMID:31054322
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
G
Atf6
activating transcription factor 6
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of ATF6 mRNA]
CTD
PMID:31054322
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
G
Atp5me
ATP synthase membrane subunit e
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ATP5ME mRNA]
CTD
PMID:19030233
NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
G
Atrnl1
attractin like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA]
CTD
PMID:19030233
NCBI chr 1:256,670,976...257,219,291
Ensembl chr 1:256,670,627...257,213,197
G
Aurkb
aurora kinase B
decreases expression
ISO
Rimonabant results in decreased expression of AURKB protein
CTD
PMID:19479993
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
G
Bax
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of BAX protein]] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of BAX protein]
CTD
PMID:27932991 PMID:30769029
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in decreased expression of BCL2 protein]]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]
CTD
PMID:26967640 PMID:30769029
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bdnf
brain-derived neurotrophic factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of BDNF mRNA]
CTD
PMID:20929960
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Braf
B-Raf proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BRAF mRNA]
CTD
PMID:19030233
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
G
Bzw1
basic leucine zipper and W2 domains 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of BZW1 mRNA]
CTD
PMID:19030233
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
G
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of C1GALT1 mRNA]
CTD
PMID:19030233
NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831
G
Cab39l
calcium binding protein 39-like
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAB39L mRNA]
CTD
PMID:19030233
NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
G
Calm1
calmodulin 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CALM1 mRNA] Rimonabant affects the expression of CALM1 mRNA
CTD
PMID:19030233
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
G
Canx
calnexin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CANX mRNA]
CTD
PMID:19030233
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
G
Capn7
calpain 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAPN7 mRNA]
CTD
PMID:19030233
NCBI chr16:6,545,630...6,581,908
Ensembl chr16:6,545,731...6,581,905
G
Cartpt
CART prepropeptide
multiple interactions increases response to substance affects expression
ISO
FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein] CARTPT results in increased susceptibility to Rimonabant
CTD
PMID:16131814
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
G
Casp1
caspase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of CASP1 protein]
CTD
PMID:27932991
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
G
Casp12
caspase 12
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CASP12 mRNA]
CTD
PMID:19030233
NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
G
Casp3
caspase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [XLR-11 results in increased activity of CASP3 protein] Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased cleavage of CASP3 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased cleavage of and results in increased activity of CASP3 protein]]
CTD
PMID:26209559 PMID:29410032 PMID:30769029
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Cav1
caveolin 1
affects expression multiple interactions
ISO
Rimonabant affects the expression of CAV1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV1 mRNA]
CTD
PMID:19030233
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
G
Cav2
caveolin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CAV2 mRNA]
CTD
PMID:19030233
NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
G
Cavin1
caveolae associated protein 1
affects expression
ISO
Rimonabant affects the expression of CAVIN1 mRNA
CTD
PMID:19030233
NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120
G
Ccar1
cell division cycle and apoptosis regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCAR1 mRNA]
CTD
PMID:19030233
NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
G
Ccl2
C-C motif chemokine ligand 2
multiple interactions decreases expression
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL2] Rimonabant results in decreased expression of CCL2 mRNA
CTD
PMID:30365523 PMID:32832534
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
G
Ccl3
C-C motif chemokine ligand 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CCL3]
CTD
PMID:32832534
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
G
Ccnb1
cyclin B1
increases expression
ISO
Rimonabant results in increased expression of CCNB1 protein
CTD
PMID:19479993
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
G
Ccnd1
cyclin D1
decreases expression
ISO
Rimonabant results in decreased expression of CCND1 protein
CTD
PMID:16822929
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
G
Ccnd2
cyclin D2
multiple interactions
ISO
Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]
CTD
PMID:26967640
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
G
Ccng1
cyclin G1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCNG1 mRNA]
CTD
PMID:19030233
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
G
Ccpg1
cell cycle progression 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CCPG1 mRNA]
CTD
PMID:19030233
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
G
Ccr7
C-C motif chemokine receptor 7
multiple interactions
ISO
[Rimonabant co-treated with MIR762 mRNA] affects the expression of CCR7 mRNA
CTD
PMID:30910812
NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
G
Cd36
CD36 molecule
affects expression multiple interactions
ISO
Rimonabant affects the expression of CD36 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA]
CTD
PMID:19030233
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Cdc73
cell division cycle 73
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDC73 mRNA]
CTD
PMID:19030233
NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
G
Cdk5
cyclin-dependent kinase 5
multiple interactions
ISO
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]; Rimonabant inhibits the reaction [Ethanol results in increased activity of CDK5 protein]
CTD
PMID:30143782
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
G
Cdk5r1
cyclin-dependent kinase 5 regulatory subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [[Ethanol results in increased activity of CDK5 protein] which results in increased degradation of CDK5R1 protein]
CTD
PMID:30143782
NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
G
Cdkl2
cyclin dependent kinase like 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CDKL2 mRNA]
CTD
PMID:19030233
NCBI chr14:16,027,381...16,063,257
Ensembl chr14:16,028,363...16,063,252
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
increases expression
ISO
Rimonabant results in increased expression of CDKN1B protein
CTD
PMID:16822929
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cebpa
CCAAT/enhancer binding protein alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [butylparaben results in increased expression of CEBPA mRNA]
CTD
PMID:27659731
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
G
Cebpd
CCAAT/enhancer binding protein delta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of CEBPD mRNA]
CTD
PMID:19030233
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
G
Chd9
chromodomain helicase DNA binding protein 9
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CHD9 mRNA]
CTD
PMID:19030233
NCBI chr19:15,941,535...16,146,220
Ensembl chr19:15,942,687...16,164,556
G
Chek1
checkpoint kinase 1
decreases phosphorylation
ISO
Rimonabant results in decreased phosphorylation of CHEK1 protein
CTD
PMID:19479993
NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
G
Clic4
chloride intracellular channel 4
affects expression multiple interactions
ISO
Rimonabant affects the expression of CLIC4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLIC4 mRNA]
CTD
PMID:19030233
NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
G
Cltc
clathrin heavy chain
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CLTC mRNA]
CTD
PMID:19030233
NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
G
Cnot1
CCR4-NOT transcription complex, subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CNOT1 mRNA]
CTD
PMID:19030233
NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
G
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNP protein]
CTD
PMID:32956517
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
G
Cnr1
cannabinoid receptor 1
multiple interactions decreases activity affects localization affects binding decreases expression
ISO EXP
1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea analog inhibits the reaction [Rimonabant binds to CNR1 protein]; 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea inhibits the reaction [Rimonabant binds to CNR1 protein]; 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Rimonabant binds to CNR1 protein]; 5F-CUMYL-PICA inhibits the reaction [Rimonabant binds to CNR1 protein]; AM 6527 inhibits the reaction [Rimonabant binds to CNR1 protein]; arachidonyl dopamine inhibits the reaction [Rimonabant binds to CNR1 protein]; Dronabinol inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate analog inhibits the reaction [Rimonabant binds to CNR1 protein]; methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate inhibits the reaction [Rimonabant binds to CNR1 protein]; N'-((3Z)-1-(1-hexyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene)benzohydrazide affects the reaction [Rimonabant binds to CNR1 protein]; N-1-naphthalenyl-1-pentyl-1H-indazole-3-carboxamide inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased activity of CNR1]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR1 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in increased abundance of Cyclic AMP]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [HU 211 results in increased activity of CNR1] Rimonabant results in decreased activity of CNR1 protein Rimonabant affects the localization of CNR1 protein Rimonabant results in decreased expression of CNR1 mRNA [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog; Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]; Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog binds to CNR1 protein]; Rimonabant inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole binds to CNR1 protein]; Rimonabant inhibits the reaction [[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] which results in decreased abundance of Nitric Oxide]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of CNR1 protein] 6-methyl-3-(2-nitro-1-(thiophen-2-yl)propyl)-2-phenyl-1H-indole inhibits the reaction [Rimonabant binds to CNR1 protein]; [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; [Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Nicotine; Rimonabant binds to and results in decreased activity of CNR1 protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CNR1 mRNA]; Rimonabant inhibits the reaction [5F-ADB cannabinoid binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [5F-ADB cannabinoid metabolite binds to and results in increased activity of CNR1 protein]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; Rimonabant inhibits the reaction [HU 211 binds to and results in increased activity of CNR1 protein]
CTD
PMID:10027878 PMID:10422789 PMID:10871313 PMID:11517236 PMID:11558437 PMID:11727767 PMID:11730719 PMID:11891798 PMID:12421626 PMID:12509806 PMID:12560108 PMID:15280883 PMID:16113085 PMID:16148442 PMID:16416159 PMID:16554168 PMID:16822929 PMID:17018694 PMID:17558434 PMID:17572696 PMID:18536748 PMID:20107430 PMID:20110567 PMID:20522703 PMID:21702498 PMID:26052038 PMID:26397760 PMID:26398720 PMID:26558620 PMID:27307500 PMID:27513693 PMID:27779402 PMID:29230395 PMID:29410032 PMID:29549157 PMID:30322873 PMID:31202911 PMID:32832534 PMID:35201352 More...
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
G
Cnr2
cannabinoid receptor 2
multiple interactions
ISO
Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole promotes the reaction [ARRB2 protein binds to CNR2 protein]]; Rimonabant inhibits the reaction [1-pentyl-3-(1-naphthoyl)indole results in increased activity of CNR2 protein]
CTD
PMID:27779402
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
G
Col1a1
collagen type I alpha 1 chain
decreases expression
EXP
Rimonabant results in decreased expression of COL1A1 mRNA
CTD
PMID:21863215 PMID:30365523
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
G
Copg2
COPI coat complex subunit gamma 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of COPG2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of COPG2 mRNA]
CTD
PMID:19030233
NCBI chr 4:59,366,086...59,501,591
Ensembl chr 4:59,366,086...59,501,618
G
Cpt1a
carnitine palmitoyltransferase 1A
increases expression
EXP
Rimonabant results in increased expression of CPT1A mRNA
CTD
PMID:30365523
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
G
Creb1
cAMP responsive element binding protein 1
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of CREB1 protein] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of and results in decreased phosphorylation of CREB1 protein]
CTD
PMID:15913574 PMID:19912468
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
G
Creb3l2
cAMP responsive element binding protein 3-like 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CREB3L2 mRNA]
CTD
PMID:19030233
NCBI chr 4:65,907,570...66,112,078
Ensembl chr 4:65,907,655...66,023,763
G
Crh
corticotropin releasing hormone
decreases expression multiple interactions
EXP
Rimonabant results in decreased expression of CRH mRNA Dronabinol affects the reaction [Rimonabant results in decreased expression of CRH mRNA]; Rimonabant inhibits the reaction [HU 211 results in decreased expression of CRH mRNA]
CTD
PMID:12968131 PMID:15099659
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Csde1
cold shock domain containing E1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CSDE1 mRNA]
CTD
PMID:19030233
NCBI chr 2:190,546,015...190,582,787
Ensembl chr 2:190,554,980...190,582,784
G
Cul1
cullin 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL1 mRNA]
CTD
PMID:19030233
NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
G
Cul3
cullin 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CUL3 mRNA]
CTD
PMID:19030233
NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462
G
Cxadr
CXADR, Ig-like cell adhesion molecule
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CXADR mRNA]
CTD
PMID:19030233
NCBI chr11:16,982,864...17,030,078
Ensembl chr11:16,982,860...17,030,046
G
Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL10]
CTD
PMID:32832534
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
G
Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of CXCL1]
CTD
PMID:32832534
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of CYP4V3 mRNA]
CTD
PMID:19030233
NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of DDIT3 mRNA]
CTD
PMID:31054322
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Ddx27
DEAD-box helicase 27
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of DDX27 mRNA]
CTD
PMID:19030233
NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372
G
Ddx3x
DEAD-box helicase 3, X-linked
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DDX3X mRNA]
CTD
PMID:19030233
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
G
Dnajc10
DnaJ heat shock protein family (Hsp40) member C10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DNAJC10 mRNA]
CTD
PMID:19030233
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
G
Dpp4
dipeptidylpeptidase 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DPP4 mRNA]
CTD
PMID:19030233
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dr1
down-regulator of transcription 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DR1 mRNA]
CTD
PMID:19030233
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
G
Dync1i2
dynein cytoplasmic 1 intermediate chain 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of DYNC1I2 mRNA]
CTD
PMID:19030233
NCBI chr 3:56,033,882...56,085,080
Ensembl chr 3:56,033,917...56,085,080
G
Edem1
ER degradation enhancing alpha-mannosidase like protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EDEM1 mRNA]
CTD
PMID:19030233
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
G
Efna5
ephrin A5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EFNA5 mRNA]
CTD
PMID:19030233
NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413
G
Ehmt2
euchromatic histone lysine methyltransferase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]
CTD
PMID:30143782
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
G
Eif4g2
eukaryotic translation initiation factor 4, gamma 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF4G2 mRNA]
CTD
PMID:19030233
NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588
G
Eif5
eukaryotic translation initiation factor 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EIF5 mRNA]
CTD
PMID:19030233
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
G
Ell2
elongation factor for RNA polymerase II 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ELL2 mRNA]
CTD
PMID:19030233
NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
G
Eps15
epidermal growth factor receptor pathway substrate 15
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of EPS15 mRNA]
CTD
PMID:19030233
NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
G
Ermp1
endoplasmic reticulum metallopeptidase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ERMP1 mRNA]
CTD
PMID:19030233
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
G
Faah
fatty acid amide hydrolase
multiple interactions
EXP ISO
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of FAAH mRNA FAAH affects the reaction [Rimonabant affects the expression of CARTPT protein]; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide]
CTD
PMID:16131814 PMID:27385208 PMID:32833042
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
G
Fam199x
family with sequence similarity 199, X-linked
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAM199X mRNA]
CTD
PMID:19030233
NCBI chr X:100,384,230...100,419,935
Ensembl chr X:100,384,225...100,414,938
G
Far1
fatty acyl CoA reductase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FAR1 mRNA]
CTD
PMID:19030233
NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730
G
Fasn
fatty acid synthase
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of FASN mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FASN mRNA]
CTD
PMID:19030233 PMID:20110567
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
G
Fbxl5
F-box and leucine-rich repeat protein 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FBXL5 mRNA]
CTD
PMID:19030233
NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383
G
Fbxw7
F-box and WD repeat domain containing 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FBXW7 mRNA]
CTD
PMID:19030233
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
G
Fem1a
fem-1 homolog A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of FEM1A mRNA]
CTD
PMID:19030233
NCBI chr 9:1,091,695...1,093,901
Ensembl chr 9:1,090,527...1,100,628
G
Fermt2
FERM domain containing kindlin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FERMT2 mRNA]
CTD
PMID:19030233
NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811
G
Fgf1
fibroblast growth factor 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FGF1 mRNA] Rimonabant affects the expression of FGF1 mRNA
CTD
PMID:19030233
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
G
Fmr1
fragile X messenger ribonucleoprotein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FMR1 mRNA]
CTD
PMID:19030233
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
G
Fndc3b
fibronectin type III domain containing 3B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FNDC3B mRNA]
CTD
PMID:19030233
NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOS protein] [Rimonabant binds to and results in decreased activity of CNR1 protein] which affects the expression of FOS protein; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein]
CTD
PMID:9751146 PMID:12560108 PMID:15280883
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSB protein]
CTD
PMID:9751146
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
G
Fosl1
FOS like 1, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL1 protein]
CTD
PMID:9751146
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
G
Fosl2
FOS like 2, AP-1 transcription factor subunit
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in increased expression of FOSL2 protein]
CTD
PMID:9751146
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
G
Frmd4b
FERM domain containing 4B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of FRMD4B mRNA]
CTD
PMID:19030233
NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
G
G6pc3
glucose 6 phosphatase catalytic subunit 3
increases expression
ISO
Rimonabant results in increased expression of G6PC3 mRNA
CTD
PMID:20110567
NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases expression
ISO
Rimonabant results in increased expression of GAPDH mRNA
CTD
PMID:16282221
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gfap
glial fibrillary acidic protein
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of GFAP protein Rimonabant inhibits the reaction [Dronabinol results in increased expression of GFAP mRNA]
CTD
PMID:21373835 PMID:36529297
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Ggps1
geranylgeranyl diphosphate synthase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GGPS1 mRNA]
CTD
PMID:19030233
NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
G
Gls
glutaminase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GLS mRNA]
CTD
PMID:19030233
NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
G
Gmfb
glia maturation factor, beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA]
CTD
PMID:19030233
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
decreases expression
ISO
Rimonabant results in decreased expression of GPLD1 mRNA
CTD
PMID:20110567
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
G
Gpr55
G protein-coupled receptor 55
multiple interactions
ISO
Rimonabant binds to and results in increased activity of GPR55 protein
CTD
PMID:17876302
NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
G
Gpt
glutamic--pyruvic transaminase
decreases expression
EXP ISO
Rimonabant results in decreased expression of GPT protein
CTD
PMID:28705172 PMID:30365523
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Grb14
growth factor receptor bound protein 14
affects expression multiple interactions
ISO
Rimonabant affects the expression of GRB14 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GRB14 mRNA]
CTD
PMID:19030233
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1] Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIA1 mRNA]
CTD
PMID:19912468 PMID:29230395
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2A]
CTD
PMID:19912468
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of GRIN2B]
CTD
PMID:19912468
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Gsta1
glutathione S-transferase alpha 1
increases expression
EXP
Rimonabant results in increased expression of GSTA1 mRNA
CTD
PMID:30365523
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
affects expression
ISO
Rimonabant affects the expression of HDHD2 mRNA
CTD
PMID:19030233
NCBI chr18:70,488,315...70,526,471
Ensembl chr18:70,474,926...70,526,470
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIF1A mRNA]
CTD
PMID:19030233
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hipk3
homeodomain interacting protein kinase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HIPK3 mRNA]
CTD
PMID:19030233
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
G
Hmox1
heme oxygenase 1
increases expression
EXP
Rimonabant results in increased expression of HMOX1 mRNA; Rimonabant results in increased expression of HMOX1 protein
CTD
PMID:30365523
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnf4a
hepatocyte nuclear factor 4, alpha
decreases activity
ISO
Rimonabant results in decreased activity of HNF4A protein
CTD
PMID:31981244
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of HSP90AA1 mRNA]
CTD
PMID:19030233
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of HSPA5 mRNA]
CTD
PMID:31054322
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Hycc2
hyccin PI4KA lipid kinase complex subunit 2
affects expression
ISO
Rimonabant affects the expression of HYCC2 mRNA
CTD
PMID:19030233
NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007
G
Icam1
intercellular adhesion molecule 1
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of ICAM1 protein Rimonabant inhibits the reaction [Glucose results in increased expression of ICAM1 protein]
CTD
PMID:21373835
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Ifng
interferon gamma
multiple interactions
EXP
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]; Rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [IFNG protein affects the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]]]; Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]; Rimonabant inhibits the reaction [Cannabinol inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]]
CTD
PMID:11520904 PMID:11727767
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Igf1
insulin-like growth factor 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGF1 mRNA]
CTD
PMID:19030233
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igfbp5
insulin-like growth factor binding protein 5
affects expression multiple interactions
ISO
Rimonabant affects the expression of IGFBP5 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IGFBP5 mRNA]
CTD
PMID:19030233
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
G
Il10
interleukin 10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]]
CTD
PMID:32385136
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il12rb2
interleukin 12 receptor subunit beta 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of IL12RB2 mRNA]
CTD
PMID:14741435 PMID:18792785
NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
G
Il18
interleukin 18
multiple interactions
ISO
Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein]
CTD
PMID:27932991
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1b
interleukin 1 beta
multiple interactions
ISO
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL1B]; Rimonabant inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Rimonabant promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
CTD
PMID:15748152 PMID:32832534
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IL6]
CTD
PMID:32832534
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ins1
insulin 1
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of INS1 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein] Rimonabant results in decreased expression of INS1 protein
CTD
PMID:19030233 PMID:26563389 PMID:26967640 PMID:30910812
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Ins2
insulin 2
decreases expression
ISO
Rimonabant results in decreased expression of INS protein
CTD
PMID:20110567
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
G
Iqgap1
IQ motif containing GTPase activating protein 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IQGAP1 mRNA] Rimonabant affects the expression of IQGAP1 mRNA
CTD
PMID:19030233
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
G
Irf5
interferon regulatory factor 5
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of IRF5]
CTD
PMID:32832534
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
G
Itgam
integrin subunit alpha M
decreases expression
EXP
Rimonabant results in decreased expression of ITGAM mRNA
CTD
PMID:30365523
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
G
Itgav
integrin subunit alpha V
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA]
CTD
PMID:19030233
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
G
Itgb1
integrin subunit beta 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGB1 mRNA]
CTD
PMID:19030233
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
G
Itpr2
inositol 1,4,5-trisphosphate receptor, type 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITPR2 mRNA]
CTD
PMID:19030233
NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
G
Ivns1abp
influenza virus NS1A binding protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]
CTD
PMID:19030233
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
G
Kif5b
kinesin family member 5B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KIF5B mRNA]
CTD
PMID:19030233
NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
G
Klf4
KLF transcription factor 4
increases expression multiple interactions
ISO
Rimonabant results in increased expression of KLF4 mRNA MIR466J mRNA affects the reaction [Rimonabant results in increased expression of KLF4 mRNA]; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of KLF4 mRNA]
CTD
PMID:30910812
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
G
Klf6
KLF transcription factor 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLF6 mRNA]
CTD
PMID:19030233
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
G
Klhl9
kelch-like family member 9
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA]
CTD
PMID:19030233
NCBI chr 5:103,333,747...103,337,931
G
Kpna3
karyopherin subunit alpha 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNA3 mRNA]
CTD
PMID:19030233
NCBI chr15:35,536,310...35,610,066
Ensembl chr15:35,536,316...35,610,419
G
Kpnb1
karyopherin subunit beta 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KPNB1 mRNA]
CTD
PMID:19030233
NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
G
Lamp2
lysosomal-associated membrane protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LAMP2 mRNA]
CTD
PMID:19030233
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Large1
LARGE xylosyl- and glucuronyltransferase 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LARGE1 mRNA] Rimonabant affects the expression of LARGE1 mRNA
CTD
PMID:19030233
NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
G
Lep
leptin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased secretion of LEP protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of BCL2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of CCND2 protein]; Rimonabant inhibits the reaction [LEP gene mutant form results in decreased expression of INS1 protein]
CTD
PMID:19030233 PMID:26967640
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lhb
luteinizing hormone subunit beta
multiple interactions
EXP
Rimonabant inhibits the reaction [Dronabinol results in decreased expression of LHB protein]
CTD
PMID:9825732
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
G
Lipc
lipase C, hepatic type
increases expression
ISO
Rimonabant results in increased expression of LIPC mRNA
CTD
PMID:20110567
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
G
Lipe
lipase E, hormone sensitive type
affects expression
ISO
Rimonabant affects the expression of LIPE mRNA
CTD
PMID:20110567
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
G
Lmo1
LIM domain only 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LMO1 mRNA]
CTD
PMID:19030233
NCBI chr 1:163,132,338...163,168,521
Ensembl chr 1:163,132,339...163,168,522
G
Lpgat1
lysophosphatidylglycerol acyltransferase 1
affects expression
ISO
Rimonabant affects the expression of LPGAT1 mRNA
CTD
PMID:19030233
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
G
Lrrfip1
LRR binding FLII interacting protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of LRRFIP1 mRNA]
CTD
PMID:19030233
NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250
G
Mag
myelin-associated glycoprotein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MAG protein]
CTD
PMID:32956517
NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions
ISO
Rimonabant results in increased expression of and results in increased lipidation of MAP1LC3B protein
CTD
PMID:31570772
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
G
Mapk1
mitogen activated protein kinase 1
multiple interactions affects localization decreases activity
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK1 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein] Rimonabant affects the localization of MAPK1 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK1 protein] Rimonabant results in decreased activity of MAPK1 protein
CTD
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions decreases activity affects localization
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK3 protein] Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] Rimonabant results in decreased activity of MAPK3 protein Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [delta(9)-tetrahydrocannabinolic acid results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [Dronabinol results in increased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [methanandamide results in increased phosphorylation of MAPK3 protein] Rimonabant affects the localization of MAPK3 protein
CTD
PMID:8526880 PMID:11553284 PMID:12657697 PMID:12834810 PMID:16282221 PMID:16822929 PMID:18950629 PMID:31917333 PMID:32510591 More...
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of MAPK8 protein]; Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of MAPK8 protein]
CTD
PMID:18950629
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Marchf6
membrane associated ring-CH-type finger 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MARCHF6 mRNA]
CTD
PMID:19030233
NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910
G
Mbnl1
muscleblind-like splicing regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL1 mRNA]
CTD
PMID:19030233
NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
G
Mbnl2
muscleblind-like splicing regulator 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MBNL2 mRNA]
CTD
PMID:19030233
NCBI chr15:97,385,278...97,542,924
Ensembl chr15:97,385,244...97,542,937
G
Mbp
myelin basic protein
multiple interactions
EXP
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of MBP protein]
CTD
PMID:17880390
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
G
Mef2c
myocyte enhancer factor 2C
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MEF2C mRNA]
CTD
PMID:36529297
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
G
Mest
mesoderm specific transcript
affects expression multiple interactions
ISO
Rimonabant affects the expression of MEST mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MEST mRNA]
CTD
PMID:19030233
NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
G
Mgll
monoglyceride lipase
affects response to substance
ISO
MGLL protein affects the susceptibility to Rimonabant
CTD
PMID:21911610
NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
G
Mir16
microRNA 16
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of MIR16 mRNA]
CTD
PMID:19030233
NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
G
Mlkl
mixed lineage kinase domain like pseudokinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein]
CTD
PMID:31220554
NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
G
Mmp13
matrix metallopeptidase 13
decreases expression
EXP
Rimonabant results in decreased expression of MMP13 mRNA
CTD
PMID:21863215
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
G
Mog
myelin oligodendrocyte glycoprotein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased expression of MOG protein]
CTD
PMID:32956517
NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
G
Mospd1
motile sperm domain containing 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MOSPD1 mRNA]
CTD
PMID:19030233
NCBI chr X:133,100,200...133,127,960
Ensembl chr X:133,100,422...133,127,908 Ensembl chr 1:133,100,422...133,127,908 Ensembl chr14:133,100,422...133,127,908
G
Mycbp2
MYC binding protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of MYCBP2 mRNA]
CTD
PMID:19030233
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
G
Nap1l1
nucleosome assembly protein 1-like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NAP1L1 mRNA]
CTD
PMID:19030233
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
G
Napepld
N-acyl phosphatidylethanolamine phospholipase D
multiple interactions
EXP
[(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of NAPEPLD mRNA
CTD
PMID:32833042
NCBI chr 4:13,360,532...13,398,815
Ensembl chr 4:13,361,006...13,398,748
G
Ncl
nucleolin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NCL mRNA]
CTD
PMID:19030233
NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136
G
Ndc1
NDC1 transmembrane nucleoporin
affects expression
ISO
Rimonabant affects the expression of NDC1 mRNA
CTD
PMID:19030233
NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
G
Ndufb11
NADH:ubiquinone oxidoreductase subunit B11
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB11 mRNA]
CTD
PMID:19030233
NCBI chr X:1,572,805...1,575,063
Ensembl chr X:1,572,785...1,575,062
G
Ndufb9
NADH:ubiquinone oxidoreductase subunit B9
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFB9 mRNA] Rimonabant affects the expression of NDUFB9 mRNA
CTD
PMID:19030233
NCBI chr 7:90,480,948...90,487,367
Ensembl chr 7:90,436,621...90,488,009
G
Ndufs8
NADH:ubiquinone oxidoreductase core subunit S8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of NDUFS8 mRNA]
CTD
PMID:19030233
NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
G
Nedd4
NEDD4 E3 ubiquitin protein ligase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEDD4 mRNA]
CTD
PMID:19030233
NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
G
Nek7
NIMA-related kinase 7
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NEK7 mRNA] Rimonabant affects the expression of NEK7 mRNA
CTD
PMID:19030233
NCBI chr13:50,022,212...50,149,374
Ensembl chr13:50,022,218...50,149,296
G
Nes
nestin
multiple interactions
ISO
[Rimonabant co-treated with Dronabinol] results in increased expression of NES mRNA
CTD
PMID:36529297
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
G
Nfatc3
nuclear factor of activated T-cells 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NFATC3 mRNA]
CTD
PMID:19030233
NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
EXP
Rimonabant results in increased expression of NFE2L2 mRNA
CTD
PMID:30365523
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nid1
nidogen 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NID1 mRNA] Rimonabant affects the expression of NID1 mRNA
CTD
PMID:19030233
NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267
G
Nlrp3
NLR family, pyrin domain containing 3
multiple interactions
ISO
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of NLRP3] Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of NLRP3 protein]
CTD
PMID:27932991 PMID:32832534
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO EXP
[Rimonabant co-treated with SR 144528] inhibits the reaction [OMDM-1 cpd inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NOS2]; Rimonabant promotes the reaction [PF 3845 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] Rimonabant inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone] results in decreased expression of NOS2 mRNA]
CTD
PMID:11520904 PMID:15748152 PMID:30910812 PMID:31121907
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Npr3
natriuretic peptide receptor 3
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NPR3 mRNA] Rimonabant affects the expression of NPR3 mRNA
CTD
PMID:19030233
NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
G
Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
EXP
Rimonabant results in increased expression of NQO1 mRNA; Rimonabant results in increased expression of NQO1 protein
CTD
PMID:30365523
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NR3C1 mRNA]
CTD
PMID:19030233
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Ntn1
netrin 1
multiple interactions decreases expression
ISO
Rimonabant affects the reaction [Dietary Fats affects the expression of NTN1 protein]; Rimonabant inhibits the reaction [Dietary Fats results in increased expression of NTN1 mRNA]; Rimonabant inhibits the reaction [MIR762 mRNA results in increased expression of NTN1 mRNA] Rimonabant results in decreased expression of NTN1 mRNA
CTD
PMID:30910812
NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
G
Opa1
OPA1, mitochondrial dynamin like GTPase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OPA1 mRNA]
CTD
PMID:19030233
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
G
Osbpl8
oxysterol binding protein-like 8
affects expression multiple interactions
ISO
Rimonabant affects the expression of OSBPL8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of OSBPL8 mRNA]
CTD
PMID:19030233
NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888
G
Pakap
paralemmin A kinase anchor protein
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PAKAP mRNA] Rimonabant affects the expression of PAKAP mRNA
CTD
PMID:19030233
NCBI chr 5:72,536,986...72,648,524 NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
G
Parp1
poly (ADP-ribose) polymerase 1
decreases expression
ISO
Rimonabant results in decreased expression of PARP1 protein
CTD
PMID:19479993
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pc
pyruvate carboxylase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PCX mRNA]
CTD
PMID:19030233
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
G
Pck1
phosphoenolpyruvate carboxykinase 1
increases expression
ISO
Rimonabant results in increased expression of PCK1 mRNA
CTD
PMID:20110567
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
G
Pcyox1
prenylcysteine oxidase 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PCYOX1 mRNA] Rimonabant affects the expression of PCYOX1 mRNA
CTD
PMID:19030233
NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951
G
Phip
pleckstrin homology domain interacting protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PHIP mRNA]
CTD
PMID:19030233
NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
affects expression multiple interactions
ISO
Rimonabant affects the expression of PIK3CA mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PIK3CA mRNA]
CTD
PMID:19030233
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Plac8
placenta associated 8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PLAC8 mRNA]
CTD
PMID:19030233
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
G
Plekha1
pleckstrin homology domain containing A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PLEKHA1 mRNA]
CTD
PMID:19030233
NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156
G
Plin2
perilipin 2
decreases expression multiple interactions
ISO
Rimonabant results in decreased expression of PLIN2 protein Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein]
CTD
PMID:31570772
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Pmm1
phosphomannomutase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PMM1 mRNA]
CTD
PMID:19030233
NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
G
Pold2
DNA polymerase delta 2, accessory subunit
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLD2 mRNA]
CTD
PMID:19030233
NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160
G
Polr2j
RNA polymerase II subunit J
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of POLR2J mRNA]
CTD
PMID:19030233
NCBI chr12:20,543,038...20,548,590
Ensembl chr12:20,543,038...20,548,594
G
Ppara
peroxisome proliferator activated receptor alpha
increases expression
EXP
Rimonabant results in increased expression of PPARA mRNA
CTD
PMID:30365523
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
affects expression
ISO
Rimonabant affects the expression of PPARG mRNA
CTD
PMID:20110567
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppfibp1
PPFIA binding protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPFIBP1 mRNA]
CTD
PMID:19030233
NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428
G
Ppp1cb
protein phosphatase 1 catalytic subunit beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP1CB mRNA]
CTD
PMID:19030233
NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
G
Ppp3ca
protein phosphatase 3 catalytic subunit alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PPP3CA mRNA]
CTD
PMID:19030233
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
G
Prkd3
protein kinase D3
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRKD3 mRNA] Rimonabant affects the expression of PRKD3 mRNA
CTD
PMID:19030233
NCBI chr 6:16,032,507...16,108,444
Ensembl chr 6:16,032,585...16,108,443
G
Prkn
parkin RBR E3 ubiquitin protein ligase
decreases response to substance multiple interactions
ISO EXP
PRKN results in decreased susceptibility to Rimonabant Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]
CTD
PMID:15882845
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
G
Prl
prolactin
multiple interactions increases expression
ISO EXP
Rimonabant inhibits the reaction [Dronabinol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]] Dronabinol affects the reaction [Rimonabant results in increased expression of PRL protein]; Rimonabant inhibits the reaction [Dronabinol results in decreased expression of PRL protein]
CTD
PMID:9825732 PMID:15099659 PMID:31154070
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
G
Prpf40a
pre-mRNA processing factor 40 homolog A
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPF40A mRNA]
CTD
PMID:19030233
NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
G
Prps1
phosphoribosyl pyrophosphate synthetase 1
affects expression multiple interactions
ISO
Rimonabant affects the expression of PRPS1 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PRPS1 mRNA]
CTD
PMID:19030233
NCBI chr X:104,132,139...104,154,191
Ensembl chr X:104,132,141...104,154,187
G
Ptbp3
polypyrimidine tract binding protein 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTBP3 mRNA]
CTD
PMID:19030233
NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
G
Pten
phosphatase and tensin homolog
affects expression multiple interactions
EXP
Rimonabant affects the expression of PTEN mRNA [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Rimonabant] affects the expression of PTEN mRNA
CTD
PMID:32833042
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
G
Ptges2
prostaglandin E synthase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of PTGES2 mRNA]
CTD
PMID:19030233
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
CTD
PMID:26209559 PMID:30769029
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptp4a1
protein tyrosine phosphatase 4A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PTP4A1 mRNA]
CTD
PMID:19030233
NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
G
Pyy
peptide YY
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of PYY mRNA]
CTD
PMID:19030233
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
G
Rac1
Rac family small GTPase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Ethanol promotes the reaction [EHMT2 protein binds to RAC1 promoter]]; Rimonabant inhibits the reaction [Ethanol results in decreased expression of RAC1 protein]
CTD
PMID:30143782
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
G
Raf1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dronabinol results in increased localization of RAF1 protein]; Rimonabant inhibits the reaction [methanandamide results in increased localization of RAF1 protein]
CTD
PMID:12834810
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
G
Ramp2
receptor activity modifying protein 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of RAMP2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RAMP2 mRNA]
CTD
PMID:19030233
NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
G
Rbms1
RNA binding motif, single stranded interacting protein 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBMS1 mRNA]
CTD
PMID:19030233
NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
G
Rbp4
retinol binding protein 4
decreases expression
ISO
rimonabant decreases expression of Rbp4 mRNA and protein in adipose tissue, aortic tissue and adipocytes
RGD
PMID:21585349
RGD:329853312
NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
G
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RBPJ mRNA]
CTD
PMID:19030233
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [JZL 184 inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] Rimonabant results in decreased expression of RELA protein
CTD
PMID:21373835 PMID:26209559
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RFNG mRNA] Rimonabant affects the expression of RFNG mRNA
CTD
PMID:19030233
NCBI chr10:106,047,221...106,050,331
Ensembl chr10:106,047,221...106,050,345
G
Rgs11
regulator of G-protein signaling 11
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RGS11 mRNA]
CTD
PMID:19030233
NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060
G
Ripk1
receptor interacting serine/threonine kinase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein]
CTD
PMID:31220554
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
G
Ripk3
receptor-interacting serine-threonine kinase 3
multiple interactions
ISO
Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein]
CTD
PMID:31220554
NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
G
rnf141
ring finger protein 141
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF141 mRNA]
CTD
PMID:19030233
NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118
G
Rnf185
ring finger protein 185
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RNF185 mRNA]
CTD
PMID:19030233
NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864
G
Rnf19a
ring finger protein 19A, RBR E3 ubiquitin protein ligase
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF19A mRNA]
CTD
PMID:19030233
NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
G
Rnf2
ring finger protein 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF2 mRNA]
CTD
PMID:19030233
NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
G
Rnf6
ring finger protein 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RNF6 mRNA]
CTD
PMID:19030233
NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847
G
Rp9
RP9, pre-mRNA splicing factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RP9 mRNA]
CTD
PMID:19030233
NCBI chr 8:20,955,447...21,005,225
Ensembl chr 8:20,941,362...21,005,175
G
Rpf2
ribosome production factor 2 homolog
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPF2 mRNA]
CTD
PMID:19030233
NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
G
Rpl18
ribosomal protein L18
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL18 mRNA]
CTD
PMID:19030233
NCBI chr 1:96,188,811...96,191,452
Ensembl chr 1:96,188,112...96,191,452
G
Rpl28
ribosomal protein L28
affects expression multiple interactions
ISO
Rimonabant affects the expression of RPL28 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL28 mRNA]
CTD
PMID:19030233
NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032
G
Rpl41
ribosomal protein L41
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPL41 mRNA]
CTD
PMID:19030233
NCBI chr 7:977,885...978,965
G
Rps10
ribosomal protein S10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS10 mRNA]
CTD
PMID:19030233
NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044 Ensembl chr 6:5,694,313...5,699,044 Ensembl chr 6:5,694,313...5,699,044
G
Rps15
ribosomal protein S15
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS15 mRNA]
CTD
PMID:19030233
NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450 Ensembl chr 7:9,416,004...9,417,450
G
Rps28
ribosomal protein S28
affects expression
ISO
Rimonabant affects the expression of RPS28 mRNA
CTD
PMID:19030233
NCBI chr 7:14,607,801...14,609,170
Ensembl chr 7:14,607,801...14,609,170 Ensembl chr16:14,607,801...14,609,170 Ensembl chr16:14,607,801...14,609,170
G
Rps6
ribosomal protein S6
decreases phosphorylation
ISO
Rimonabant results in decreased phosphorylation of RPS6 protein
CTD
PMID:30687088
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
G
Rps8
ribosomal protein S8
affects expression multiple interactions
ISO
Rimonabant affects the expression of RPS8 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RPS8 mRNA]
CTD
PMID:19030233
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
G
Rras2
RAS related 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RRAS2 mRNA]
CTD
PMID:19030233
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
G
Rxrb
retinoid X receptor beta
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of RXRB mRNA]
CTD
PMID:19030233
NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
G
Ryk
receptor-like tyrosine kinase
affects expression multiple interactions
ISO
Rimonabant affects the expression of RYK mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of RYK mRNA]
CTD
PMID:19030233
NCBI chr 8:103,419,338...103,492,083
Ensembl chr 8:103,419,275...103,491,698
G
Scarb1
scavenger receptor class B, member 1
increases expression
ISO
Rimonabant results in increased expression of SCARB1 mRNA
CTD
PMID:20110567
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
G
Scd
stearoyl-CoA desaturase
decreases expression
ISO
Rimonabant results in decreased expression of SCD1 mRNA
CTD
PMID:20110567
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scd2
stearoyl-Coenzyme A desaturase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SCD2 mRNA]
CTD
PMID:19030233
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
G
Scoc
short coiled-coil protein
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SCOC mRNA]
CTD
PMID:19030233
NCBI chr19:24,659,651...24,689,237
Ensembl chr19:24,659,651...24,693,217
G
Sec62
SEC62 homolog, preprotein translocation factor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC62 mRNA]
CTD
PMID:19030233
NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814
G
Sec63
SEC63 homolog, protein translocation regulator
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEC63 mRNA]
CTD
PMID:19030233
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
G
Sema3c
semaphorin 3C
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEMA3C mRNA]
CTD
PMID:19030233
NCBI chr 4:17,583,212...17,747,234
Ensembl chr 4:17,583,212...17,746,534
G
Sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
affects expression
ISO
Rimonabant affects the expression of SEPSECS mRNA
CTD
PMID:19030233
NCBI chr14:58,311,484...58,341,745
Ensembl chr14:58,311,499...58,341,740
G
Septin2
septin 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SEPTIN2 mRNA]
CTD
PMID:19030233
NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
G
Septin6
septin 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SEPTIN6 mRNA]
CTD
PMID:19030233
NCBI chr X:116,153,255...116,230,334
Ensembl chr X:116,153,255...116,230,115
G
Serpinb6a
serpin family B member 6A
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SERPINB6A mRNA] Rimonabant affects the expression of SERPINB6A mRNA
CTD
PMID:19030233
NCBI chr17:30,871,468...30,989,703
Ensembl chr17:30,871,468...31,014,427
G
Serpine1
serpin family E member 1
decreases expression
EXP
Rimonabant results in decreased expression of SERPINE1 protein
CTD
PMID:17882151
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
G
Sestd1
SEC14 and spectrin domain containing 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SESTD1 mRNA] Rimonabant affects the expression of SESTD1 mRNA
CTD
PMID:19030233
NCBI chr 3:62,123,590...62,220,759
Ensembl chr 3:62,129,887...62,220,546
G
Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SGTA mRNA]
CTD
PMID:19030233
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
G
Sh3bgrl1
SH3 domain binding glutamate rich protein like 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SH3BGRL mRNA]
CTD
PMID:19030233
NCBI chr X:74,167,029...74,263,783
Ensembl chr X:74,166,871...74,263,783
G
Sipa1l1
signal-induced proliferation-associated 1 like 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SIPA1L1 mRNA] Rimonabant affects the expression of SIPA1L1 mRNA
CTD
PMID:19030233
NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
G
Slc2a4
solute carrier family 2 member 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA]
CTD
PMID:19030233
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
G
Slc39a10
solute carrier family 39 member 10
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A10 mRNA]
CTD
PMID:19030233
NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
G
Slc39a8
solute carrier family 39 member 8
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SLC39A8 mRNA]
CTD
PMID:19030233
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
G
Smarca2
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SMARCA2 mRNA]
CTD
PMID:19030233
NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
G
Socs1
suppressor of cytokine signaling 1
decreases expression
EXP
Rimonabant results in decreased expression of SOCS1 mRNA
CTD
PMID:30365523
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
G
Socs3
suppressor of cytokine signaling 3
decreases expression
EXP
Rimonabant results in decreased expression of SOCS3 mRNA
CTD
PMID:30365523
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
G
Sorbs2
sorbin and SH3 domain containing 2
affects expression
ISO
Rimonabant affects the expression of SORBS2 mRNA
CTD
PMID:19030233
NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514
G
Sparc
secreted protein acidic and cysteine rich
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPARC mRNA] Rimonabant affects the expression of SPARC mRNA
CTD
PMID:19030233
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
G
Sptbn1
spectrin, beta, non-erythrocytic 1
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SPTBN1 mRNA] Rimonabant affects the expression of SPTBN1 mRNA
CTD
PMID:19030233
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
G
Src
SRC proto-oncogene, non-receptor tyrosine kinase
multiple interactions
ISO
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of SRC protein]
CTD
PMID:16046413
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
G
Srp72
signal recognition particle 72
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of SRP72 mRNA]
CTD
PMID:19030233
NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
G
St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ST3GAL6 mRNA]
CTD
PMID:19030233
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
G
Stat3
signal transducer and activator of transcription 3
multiple interactions
ISO
Rimonabant inhibits the reaction [HU 211 results in increased phosphorylation of STAT3 protein]
CTD
PMID:16046413
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stat6
signal transducer and activator of transcription 6
multiple interactions
ISO
[MIR466J mRNA co-treated with Rimonabant] affects the expression of STAT6 mRNA; Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STAT6 mRNA]
CTD
PMID:30910812
NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
G
Stim2
stromal interaction molecule 2
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of STIM2 mRNA] Rimonabant affects the expression of STIM2 mRNA
CTD
PMID:19030233
NCBI chr14:56,878,428...57,004,405
Ensembl chr14:56,878,645...57,004,179
G
Strn4
striatin 4
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of STRN4 mRNA]
CTD
PMID:19030233
NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858
G
Tcea1
transcription elongation factor A1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TCEA1 mRNA]
CTD
PMID:19030233
NCBI chr 5:14,631,454...14,668,769
Ensembl chr 5:14,631,454...14,668,745 Ensembl chr15:14,631,454...14,668,745
G
Tgfb1
transforming growth factor, beta 1
decreases expression
EXP
Rimonabant results in decreased expression of TGFB1 mRNA
CTD
PMID:30365523
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Tgif2
TGFB-induced factor homeobox 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TGIF2 mRNA]
CTD
PMID:19030233
NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596 Ensembl chr17:145,333,418...145,348,596
G
Th
tyrosine hydroxylase
multiple interactions increases activity
EXP
Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein]; Rimonabant inhibits the reaction [Dronabinol results in increased activity of TH protein] Rimonabant results in increased activity of TH protein
CTD
PMID:9188039 PMID:10700552 PMID:15882845
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
G
Thy1
Thy-1 cell surface antigen
multiple interactions
EXP
Rimonabant inhibits the reaction [methanandamide affects the expression of THY1 mRNA]
CTD
PMID:17591864
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
G
Timp1
TIMP metallopeptidase inhibitor 1
decreases expression
EXP
Rimonabant results in decreased expression of TIMP1 mRNA
CTD
PMID:21863215 PMID:30365523
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
G
Tmed7
transmembrane p24 trafficking protein 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TMED7 mRNA]
CTD
PMID:19030233
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
G
Tnf
tumor necrosis factor
multiple interactions decreases expression
ISO EXP
Rimonabant inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TNF]; Rimonabant inhibits the reaction [forsythiaside inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]] Rimonabant results in decreased expression of TNF mRNA
CTD
PMID:20110567 PMID:30365523 PMID:30769029 PMID:32832534
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tomm20
translocase of outer mitochondrial membrane 20
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TOMM20 mRNA]
CTD
PMID:19030233
NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198
G
Tpm4
tropomyosin 4
affects expression multiple interactions
ISO
Rimonabant affects the expression of TPM4 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of TPM4 mRNA]
CTD
PMID:19030233
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
G
Trpv1
transient receptor potential cation channel, subfamily V, member 1
multiple interactions
ISO
Rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [Capsaicin binds to and results in increased activity of TRPV1 protein]; Rimonabant inhibits the reaction [N-(4-hydroxyphenyl)arachidonylamide binds to and results in increased activity of TRPV1 protein]
CTD
PMID:11278420
NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
G
Tsen2
tRNA splicing endonuclease subunit 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of TSEN2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSEN2 mRNA]
CTD
PMID:19030233
NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
G
Tspan5
tetraspanin 5
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of TSPAN5 mRNA]
CTD
PMID:19030233
NCBI chr 2:227,294,180...227,469,361
Ensembl chr 2:227,294,217...227,465,664
G
Txnrd1
thioredoxin reductase 1
increases expression
EXP
Rimonabant results in increased expression of TXNRD1 mRNA
CTD
PMID:30365523
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Unc5b
unc-5 netrin receptor B
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of UNC5B mRNA]
CTD
PMID:30910812
NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
G
Usp46
ubiquitin specific peptidase 46
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP46 mRNA]
CTD
PMID:19030233
NCBI chr14:34,150,055...34,219,227
Ensembl chr14:34,150,004...34,219,227
G
Usp48
ubiquitin specific peptidase 48
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of USP48 mRNA]
CTD
PMID:19030233
NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
G
Vcam1
vascular cell adhesion molecule 1
multiple interactions decreases expression
ISO
Rimonabant inhibits the reaction [Glucose results in increased expression of VCAM1 protein] Rimonabant results in decreased expression of VCAM1 protein
CTD
PMID:21373835
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
G
Vcl
vinculin
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VCL mRNA]
CTD
PMID:19030233
NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
G
Vegfa
vascular endothelial growth factor A
multiple interactions
ISO
Rimonabant inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in decreased expression of and results in decreased secretion of VEGFA protein]
CTD
PMID:15313899
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
G
Vim
vimentin
multiple interactions affects expression
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VIM mRNA] Rimonabant affects the expression of VIM mRNA
CTD
PMID:19030233
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
G
Vldlr
very low density lipoprotein receptor
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of VLDLR mRNA]
CTD
PMID:19030233
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
G
Wdr26
WD repeat domain 26
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WDR26 mRNA]
CTD
PMID:19030233
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
G
Wdr7
WD repeat domain 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of WDR7 mRNA]
CTD
PMID:19030233
NCBI chr18:57,165,482...57,448,568
Ensembl chr18:57,165,488...57,448,540
G
Wsb1
WD repeat and SOCS box-containing 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WSB1 mRNA]
CTD
PMID:19030233
NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
G
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWP1 mRNA]
CTD
PMID:19030233
NCBI chr 5:33,092,379...33,185,887
Ensembl chr 5:33,098,494...33,186,046
G
Wwtr1
WW domain containing transcription regulator 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of WWTR1 mRNA]
CTD
PMID:19030233
NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968
G
Xbp1
X-box binding protein 1
increases expression multiple interactions
ISO
Rimonabant results in increased expression of XBP1 mRNA [Rimonabant co-treated with SR 144528] inhibits the reaction [Dronabinol results in increased expression of XBP1 mRNA alternative form]; Gemcitabine promotes the reaction [Rimonabant results in increased expression of XBP1 mRNA]
CTD
PMID:21525939 PMID:31054322
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Zdhhc2
zinc finger DHHC-type palmitoyltransferase 2
affects expression multiple interactions
ISO
Rimonabant affects the expression of ZDHHC2 mRNA Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZDHHC2 mRNA]
CTD
PMID:19030233
NCBI chr16:51,808,465...51,878,060
Ensembl chr16:51,808,468...51,878,060
G
Zdhhc7
zinc finger DHHC-type palmitoyltransferase 7
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in decreased expression of ZDHHC7 mRNA]
CTD
PMID:19030233
NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673
G
Zhx1
zinc fingers and homeoboxes 1
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZHX1 mRNA]
CTD
PMID:19030233
NCBI chr 7:89,582,363...89,611,337
Ensembl chr 7:89,582,243...89,611,264
G
Znrf2
zinc and ring finger 2
multiple interactions
ISO
Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ZNRF2 mRNA]
CTD
PMID:19030233
NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818
G
Zwilch
zwilch kinetochore protein
affects expression
ISO
Rimonabant affects the expression of ZWILCH mRNA
CTD
PMID:19030233
NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all