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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Ro 61-8048
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Accession:CHEBI:34953 term browser browse the term
Definition:A C-nitro compound that has formula C17H15N3O6S2.
Synonyms:related_synonym: Formula=C17H15N3O6S2;   InChI=1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19);   InChIKey=NDPBMCKQJOZAQX-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1OC)S(=O)(=O)Nc1nc(cs1)-c1cccc(c1)[N+]([O-])=O
 xref: CAS:199666-03-0;   KEGG:C14126
 xref_mesh: MESH:C110196


show annotations for term's descendants           Sort by:
Ro 61-8048 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase multiple interactions
decreases activity		 EXP [Ro 61-8048 results in decreased activity of KMO protein] which results in increased abundance of Kynurenic Acid CTD PMID:30151725 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    chemical entity 19865
      group 19818
        inorganic group 19399
          nitro group 11128
            nitro compound 11128
              C-nitro compound 10853
                Ro 61-8048 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            organic molecule 19692
                              C-nitro compound 10853
                                Ro 61-8048 1
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