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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Olprinone hydrochloride
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Accession:CHEBI:34902 term browser browse the term
Definition:An organic molecular entity that has formula C14H10N4O.HCl.
Synonyms:related_synonym: E 1020;   Formula=C14H10N4O.HCl;   InChI=1S/C14H10N4O.ClH/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10;/h2-6,8H,1H3,(H,17,19);1H;   InChIKey=PWTBMBAQRAOAFF-UHFFFAOYSA-N;   SMILES=Cl.Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N
 xref: CAS:119615-63-3;   KEGG:C13546
 xref_mesh: MESH:C059498



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Olprinone hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases activity
multiple interactions
EXP olprinone results in increased activity of AKT1 protein
zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of AKT1 protein]
CTD PMID:19387321 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP olprinone results in increased expression of and results in increased activity of HMOX1 protein; zinc protoporphyrin inhibits the reaction [olprinone results in increased activity of HMOX1 protein] CTD PMID:19387321 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Pde3a phosphodiesterase 3A decreases activity ISO olprinone results in decreased activity of PDE3A protein CTD PMID:16325808 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          carbon atom 20710
            organic molecular entity 20710
              Olprinone hydrochloride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            Olprinone hydrochloride 3
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