CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Norethindrone enanthate
Accession: CHEBI:34894
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Definition: A steroid ester that has formula C27H38O3.
Synonyms: related_synonym: 17alpha-Ethynyl-17beta-heptanoyloxy-4-estren-3-one; Formula=C27H38O3; InChI=1S/C27H38O3/c1-4-6-7-8-9-25(29)30-27(5-2)17-15-24-23-12-10-19-18-20(28)11-13-21(19)22(23)14-16-26(24,27)3/h2,18,21-24H,4,6-17H2,1,3H3/t21-,22+,23+,24-,26-,27-/m0/s1; InChIKey=APTGJECXMIKIET-WOSSHHRXSA-N; Norethisterone enanthate; SMILES=CCCCCCC(=O)O[C@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C#C; norethisterone heptanoate; norigest; noristerat
xref: CAS:3836-23-5; Drug_Central:1964; KEGG:C14486; KEGG:D08285
xref_mesh: MESH:C024319
G
Ar
androgen receptor
multiple interactions affects localization
ISO
norethindrone enanthate binds to and results in increased activity of AR protein norethindrone enanthate affects the localization of AR protein
CTD
PMID:28478275
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
[norethindrone enanthate co-treated with Estradiol] results in decreased expression of BCL2 mRNA
CTD
PMID:18829022
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Cycs
cytochrome c, somatic
multiple interactions
EXP
[norethindrone enanthate co-treated with Estradiol] results in increased expression of CYCS mRNA
CTD
PMID:18829022
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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