The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.
ESR1 protein affects the reaction [Ethisterone results in increased expression of GREB1 mRNA]; ESR1 protein affects the reaction [Ethisterone results in increased expression of SGK1 mRNA]
ESR1 protein affects the reaction [Ethisterone results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of GREB1 mRNA]
ESR1 protein affects the reaction [Ethisterone results in increased expression of SGK1 mRNA]; Fulvestrant inhibits the reaction [Ethisterone results in increased expression of SGK1 mRNA]