CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | 1-chloro-2,4-dinitrobenzene |
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Accession: | CHEBI:34718
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browse the term
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Definition: | A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions. |
Synonyms: | related_synonym: | 1,3-Dinitro-4-chlorobenzene; 1-Chloro-2,4-dinitrobenzol; 2,4-Dinitro-1-chlorobenzene; 2,4-Dinitrochlorobenzene; 2,4-Dinitrophenyl chloride; 4-Chloro-1,3-dinitrobenzene; 6-Chloro-1,3-dinitrobenzene; Cdnb; Chlorodinitrobenzene; ClDNB; DNPCl; Dinitrochlorobenzene; Dncb; Formula=C6H3ClN2O4; InChI=1S/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H; InChIKey=VYZAHLCBVHPDDF-UHFFFAOYSA-N; SMILES=[O-][N+](=O)c1ccc(Cl)c(c1)[N+]([O-])=O |
| xref: | Beilstein:613161; CAS:97-00-7; Gmelin:28481; KEGG:C14397 |
| xref_mesh: | MESH:D004137 |
| xref: | PMID:1155304; PMID:12176098; PMID:1447476; PMID:15009707; PMID:15588915; PMID:1640019; PMID:18316151; PMID:18775882; PMID:19171927; PMID:1982449; PMID:25515858; PMID:29079364; PMID:3180787; PMID:6446435; PMID:7059096; PMID:7179722; PMID:7994925; Reaxys:613161; Wikipedia:2\,4-Dinitrochlorobenzene |
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Aars1 |
alanyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AARS1 protein |
CTD |
PMID:32991956 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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Abca6 |
ATP binding cassette subfamily A member 6 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of ABCA6 mRNA |
CTD |
PMID:17374397 |
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NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
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Abcc2 |
ATP binding cassette subfamily C member 2 |
decreases response to substance |
ISO |
ABCC2 protein results in decreased susceptibility to Dinitrochlorobenzene |
CTD |
PMID:26049102 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abhd10 |
abhydrolase domain containing 10, depalmitoylase |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of ABHD10 mRNA |
CTD |
PMID:17374397 |
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NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866
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Abhd11 |
abhydrolase domain containing 11 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ABHD11 protein |
CTD |
PMID:32991956 |
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NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398
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Acat2 |
acetyl-CoA acetyltransferase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ACAT2 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acly |
ATP citrate lyase |
affects binding |
ISO |
Dinitrochlorobenzene binds to ACLY protein |
CTD |
PMID:32991956 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Acod1 |
aconitate decarboxylase 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of ACOD1 mRNA |
CTD |
PMID:22302311 |
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NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
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Acox2 |
acyl-CoA oxidase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ACOX2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acp1 |
acid phosphatase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ACP1 protein |
CTD |
PMID:32991956 |
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NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ACSL1 protein |
CTD |
PMID:32991956 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ACSL4 protein |
CTD |
PMID:32991956 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Actb |
actin, beta |
increases metabolic processing affects binding |
ISO |
Dinitrochlorobenzene results in increased metabolism of ACTB protein Dinitrochlorobenzene binds to ACTB protein |
CTD |
PMID:29267982 PMID:32991956 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Adamts15 |
ADAM metallopeptidase with thrombospondin type 1 motif, 15 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ADAMTS15 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
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Adm |
adrenomedullin |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ADM mRNA |
CTD |
PMID:25236440 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adnp2 |
ADNP homeobox 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ADNP2 protein |
CTD |
PMID:32991956 |
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NCBI chr18:73,571,870...73,597,088
Ensembl chr18:73,571,936...73,628,484
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Adora2b |
adenosine A2B receptor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ADORA2B mRNA |
CTD |
PMID:16314067 |
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NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
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Adsl |
adenylosuccinate lyase |
affects binding |
ISO |
Dinitrochlorobenzene binds to ADSL protein |
CTD |
PMID:32991956 |
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NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760
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Afg2b |
AFG2 AAA ATPase homolog B |
affects binding |
ISO |
Dinitrochlorobenzene binds to AFG2B protein |
CTD |
PMID:32991956 |
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NCBI chr 3:109,694,739...109,708,356
Ensembl chr 3:109,694,757...109,707,757
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Aicda |
activation-induced cytidine deaminase |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of AICDA mRNA |
CTD |
PMID:22302311 |
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NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
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Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AIFM1 protein |
CTD |
PMID:32991956 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Akap13 |
A-kinase anchoring protein 13 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AKAP13 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646
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Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of AKR1B1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of AKR1B10 mRNA |
CTD |
PMID:20566472 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of AKR1C1 mRNA |
CTD |
PMID:20566472 |
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NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases activity increases expression |
ISO |
Dinitrochlorobenzene results in increased activity of AKR1C2 promoter Dinitrochlorobenzene results in increased expression of AKR1C2 mRNA |
CTD |
PMID:20491607 PMID:20713136 PMID:21195160 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1c3 |
aldo-keto reductase family 1, member C3 |
increases expression affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA Dinitrochlorobenzene affects the expression of AKR1C18 mRNA |
CTD |
PMID:20566472 PMID:22302311 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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Akt2 |
AKT serine/threonine kinase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AKT2 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Alb |
albumin |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of ALB protein |
CTD |
PMID:29267982 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Ankrd12 |
ankyrin repeat domain 12 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ANKRD12 protein |
CTD |
PMID:32991956 |
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NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
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Ankrd2 |
ankyrin repeat domain 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ANKRD2 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
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Ankrd35 |
ankyrin repeat domain 35 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ANKRD35 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:184,207,076...184,227,063
Ensembl chr 2:184,207,071...184,227,063
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Ankrd37 |
ankyrin repeat domain 37 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ANKRD37 mRNA |
CTD |
PMID:25236440 |
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NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
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Anxa1 |
annexin A1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ANXA1 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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Anxa2 |
annexin A2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ANXA2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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Anxa3 |
annexin A3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ANXA3 protein |
CTD |
PMID:32991956 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Ap1b1 |
adaptor related protein complex 1 subunit beta 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AP1B1 protein |
CTD |
PMID:32991956 |
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NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
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Ap2a1 |
adaptor related protein complex 2 subunit alpha 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AP2A1 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:95,384,306...95,414,170
Ensembl chr 1:95,384,309...95,414,147
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Ap2b1 |
adaptor related protein complex 2 subunit beta 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AP2B1 protein |
CTD |
PMID:32991956 |
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NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
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Ap3d1 |
adaptor related protein complex 3 subunit delta 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to AP3D1 protein |
CTD |
PMID:32991956 |
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NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643
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Aqr |
aquarius intron-binding spliceosomal factor |
affects binding |
ISO |
Dinitrochlorobenzene binds to AQR protein |
CTD |
PMID:32991956 |
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NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044
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Arf5 |
ADP-ribosylation factor 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ARF5 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441
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Arg2 |
arginase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ARG2 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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Arl4c |
ADP ribosylation factor like GTPase 4C |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ARL4C mRNA |
CTD |
PMID:17374397 |
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NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
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Arpc2 |
actin related protein 2/3 complex, subunit 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ARPC2 protein |
CTD |
PMID:32991956 |
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NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
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Arpc3 |
actin related protein 2/3 complex, subunit 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ARPC3 protein |
CTD |
PMID:32991956 |
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NCBI chr12:34,172,780...34,186,651
Ensembl chr12:34,172,780...34,186,651
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Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ASNS mRNA |
CTD |
PMID:18242016 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Ass1 |
argininosuccinate synthase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ASS1 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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Atf3 |
activating transcription factor 3 |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of ATF3 mRNA KN 62 inhibits the reaction [Dinitrochlorobenzene results in increased expression of ATF3 mRNA] |
CTD |
PMID:23999411 PMID:27965148 PMID:28941582 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
affects binding |
ISO |
Dinitrochlorobenzene binds to ATIC protein |
CTD |
PMID:32991956 |
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NCBI chr 9:73,164,846...73,184,897
Ensembl chr 9:73,164,846...73,184,889
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Atp5f1a |
ATP synthase F1 subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to ATP5F1A protein |
CTD |
PMID:32991956 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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Azin1 |
antizyme inhibitor 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of AZIN1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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B2m |
beta-2 microglobulin |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of B2M mRNA |
CTD |
PMID:28219650 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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Bach1 |
BTB domain and CNC homolog 1 |
multiple interactions |
ISO |
BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA] |
CTD |
PMID:26244607 |
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NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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Bambi |
BMP and activin membrane-bound inhibitor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BAMBI mRNA |
CTD |
PMID:20146380 |
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NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
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Bcl2 |
BCL2, apoptosis regulator |
multiple interactions affects expression |
ISO |
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA] Dinitrochlorobenzene affects the expression of BCL2 mRNA |
CTD |
PMID:28219650 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bclaf1 |
BCL2-associated transcription factor 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of BCLAF1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
EXP |
Dinitrochlorobenzene inhibits the reaction [BDNF protein results in decreased susceptibility to 3-nitropropionic acid] |
CTD |
PMID:19428112 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Bmp6 |
bone morphogenetic protein 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BMP6 mRNA |
CTD |
PMID:17374397 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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Bspry |
B-box and SPRY domain containing |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BSPRY mRNA |
CTD |
PMID:18242016 |
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NCBI chr 5:75,927,397...75,949,585
Ensembl chr 5:75,927,405...75,949,583
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Bst2 |
bone marrow stromal cell antigen 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BST2 mRNA |
CTD |
PMID:19647056 |
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NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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Btg1 |
BTG anti-proliferation factor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BTG1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
decreases expression increases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of BUB1 mRNA Dinitrochlorobenzene results in increased expression of BUB1 mRNA |
CTD |
PMID:17374397 PMID:21404309 |
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NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of BUB1B mRNA |
CTD |
PMID:21404309 |
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NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C3 |
complement C3 |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of C3 protein |
CTD |
PMID:29267982 |
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NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Calca |
calcitonin-related polypeptide alpha |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CALCA mRNA |
CTD |
PMID:20146380 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Calcrl |
calcitonin receptor like receptor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CALCRL mRNA |
CTD |
PMID:17374397 |
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NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910
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G |
Canx |
calnexin |
affects binding |
ISO |
Dinitrochlorobenzene binds to CANX protein |
CTD |
PMID:32991956 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Capza2 |
capping actin protein of muscle Z-line subunit alpha 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CAPZA2 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864
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G |
Car2 |
carbonic anhydrase 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CA2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Casp1 |
caspase 1 |
increases expression increases phosphorylation increases activity multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of CASP1 mRNA Dinitrochlorobenzene results in increased phosphorylation of CASP1 protein Dinitrochlorobenzene results in increased activity of CASP1 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] |
CTD |
PMID:28219650 PMID:30842373 PMID:31276767 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
decreases expression increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in decreased expression of CASP3 mRNA Dinitrochlorobenzene results in increased expression of CASP3 mRNA; Dinitrochlorobenzene results in increased expression of CASP3 protein sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 protein] |
CTD |
PMID:28219650 PMID:34651546 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8ap2 |
caspase 8 associated protein 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CASP8AP2 protein |
CTD |
PMID:32991956 |
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NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
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G |
Casp9 |
caspase 9 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CASP9 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
increases expression multiple interactions decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CAT mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of CAT protein] |
CTD |
PMID:20566472 PMID:28219650 PMID:34651546 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions increases expression |
ISO |
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL11 mRNA] |
CTD |
PMID:23133493 |
|
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCL12 mRNA |
CTD |
PMID:19647056 |
|
NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
multiple interactions increases expression |
ISO |
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL17 protein] Dinitrochlorobenzene results in increased expression of CCL17 mRNA; Dinitrochlorobenzene results in increased expression of CCL17 protein |
CTD |
PMID:15491423 PMID:21404309 PMID:23454147 |
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NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
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G |
Ccl19 |
C-C motif chemokine ligand 19 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCL19 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
decreases expression decreases secretion increases secretion increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in decreased expression of CCL2 mRNA Dinitrochlorobenzene results in decreased secretion of CCL2 protein Dinitrochlorobenzene results in increased secretion of CCL2 protein Dinitrochlorobenzene results in increased expression of CCL2 mRNA Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL2 mRNA] |
CTD |
PMID:15585374 PMID:17374397 PMID:19647056 PMID:20488241 PMID:20713136 PMID:21404309 PMID:22245253 PMID:23133493 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CCL20 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CCL22 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression affects expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of CCL3 mRNA Dinitrochlorobenzene affects the expression of CCL3 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA] |
CTD |
PMID:15585374 PMID:19647056 PMID:20146380 PMID:28219650 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
increases expression increases secretion |
ISO |
Dinitrochlorobenzene results in increased expression of CCL4 mRNA Dinitrochlorobenzene results in increased secretion of CCL4 protein Dinitrochlorobenzene results in increased expression of CCL4 mRNA; Dinitrochlorobenzene results in increased expression of CCL4 protein |
CTD |
PMID:15585374 PMID:16314067 PMID:18353026 PMID:19647056 PMID:20146380 PMID:28219650 More...
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NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions increases expression increases secretion decreases expression |
ISO |
diflorasone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL5 protein] Dinitrochlorobenzene results in increased secretion of CCL5 protein Dinitrochlorobenzene results in decreased expression of CCL5 mRNA |
CTD |
PMID:15491423 PMID:20488241 PMID:21404309 PMID:28219650 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
increases expression |
EXP ISO |
Dinitrochlorobenzene results in increased expression of CCL7 mRNA |
CTD |
PMID:19647056 PMID:21404309 PMID:21893156 |
|
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
increases expression affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCL6 mRNA Dinitrochlorobenzene affects the expression of CCL6 mRNA |
CTD |
PMID:19647056 PMID:21404309 PMID:22302311 |
|
NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccna2 |
cyclin A2 |
affects expression increases expression |
ISO |
Dinitrochlorobenzene affects the expression of CCNA2 mRNA Dinitrochlorobenzene results in increased expression of CCNA2 mRNA |
CTD |
PMID:21404309 PMID:22302311 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CCNB1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCNB2 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccne1 |
cyclin E1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCNE1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccne2 |
cyclin E2 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CCNE2 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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G |
Ccnf |
cyclin F |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCNF mRNA |
CTD |
PMID:18242016 |
|
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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G |
Ccr1 |
C-C motif chemokine receptor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCR1 mRNA |
CTD |
PMID:19647056 |
|
NCBI chr 8:123,556,286...123,561,841
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
decreases expression increases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CCR2 mRNA Dinitrochlorobenzene results in increased expression of CCR2 mRNA |
CTD |
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20713136 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
multiple interactions increases expression |
ISO |
Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCR3 mRNA] |
CTD |
PMID:23133493 |
|
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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G |
Ccr4 |
C-C motif chemokine receptor 4 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CCR4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CCR5 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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G |
Ccr6 |
C-C motif chemokine receptor 6 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CCR6 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
increases expression multiple interactions decreases expression |
EXP ISO |
Dinitrochlorobenzene results in increased expression of CCR7 mRNA Dinitrochlorobenzene results in increased expression of CCR7 mRNA; Dinitrochlorobenzene results in increased expression of CCR7 protein TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene results in decreased expression of CCR7 mRNA |
CTD |
PMID:15304089 PMID:15737199 PMID:17374397 PMID:19159591 PMID:19371601 PMID:20713136 PMID:28219650 More...
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NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Cct3 |
chaperonin containing TCP1 subunit 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CCT3 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
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G |
Cct4 |
chaperonin containing TCP1 subunit 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CCT4 protein |
CTD |
PMID:32991956 |
|
NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CCT5 protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd109 |
CD109 molecule |
affects binding increases expression |
ISO |
Dinitrochlorobenzene binds to CD109 protein Dinitrochlorobenzene results in increased expression of CD109 protein |
CTD |
PMID:32991956 PMID:33774146 |
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NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194
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G |
Cd160 |
CD160 molecule |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CD160 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
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G |
Cd207 |
CD207 molecule |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CD207 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 4:116,155,229...116,161,587
Ensembl chr 4:116,155,212...116,161,518
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G |
Cd274 |
CD274 molecule |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CD274 mRNA; Dinitrochlorobenzene results in increased expression of CD274 protein |
CTD |
PMID:20488241 PMID:28941582 |
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NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
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G |
Cd36 |
CD36 molecule |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CD36 mRNA |
CTD |
PMID:17374397 PMID:21404309 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd40 |
CD40 molecule |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CD40 protein |
CTD |
PMID:17636246 PMID:21742781 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd5l |
Cd5 molecule-like |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CD5L mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CD80 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Cd83 |
CD83 molecule |
affects expression increases expression decreases expression |
ISO |
Dinitrochlorobenzene affects the expression of CD83 mRNA Dinitrochlorobenzene results in increased expression of CD83 mRNA; Dinitrochlorobenzene results in increased expression of CD83 protein Dinitrochlorobenzene results in decreased expression of CD83 mRNA |
CTD |
PMID:17636246 PMID:22302311 PMID:28219650 PMID:28941582 |
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NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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G |
Cd86 |
CD86 molecule |
increases expression multiple interactions affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of CD86 mRNA; Dinitrochlorobenzene results in increased expression of CD86 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; bisindolylmaleimide I inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Cysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Vitamin E inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein] Dinitrochlorobenzene affects the expression of CD86 mRNA |
CTD |
PMID:12423654 PMID:15737199 PMID:17374397 PMID:17636246 PMID:19033392 PMID:19665512 PMID:20417223 PMID:20457211 PMID:20488241 PMID:21742781 PMID:24136171 PMID:28219650 PMID:28389280 PMID:29743441 PMID:30842373 PMID:33774146 More...
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc20 |
cell division cycle 20 |
affects expression increases expression |
ISO |
Dinitrochlorobenzene affects the expression of CDC20 mRNA Dinitrochlorobenzene results in increased expression of CDC20 mRNA |
CTD |
PMID:21404309 PMID:22302311 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc25c |
cell division cycle 25C |
affects expression increases expression |
ISO |
Dinitrochlorobenzene affects the expression of CDC25C mRNA Dinitrochlorobenzene results in increased expression of CDC25C mRNA |
CTD |
PMID:21404309 PMID:22302311 |
|
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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G |
Cdc45 |
cell division cycle 45 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CDC45 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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G |
Cdc5l |
cell division cycle 5-like |
affects binding |
ISO |
Dinitrochlorobenzene binds to CDC5L protein |
CTD |
PMID:32991956 |
|
NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450
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G |
Cdc6 |
cell division cycle 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CDC6 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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G |
Cdca2 |
cell division cycle associated 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CDCA2 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
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G |
Cdh8 |
cadherin 8 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CDH8 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
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G |
Cdk1 |
cyclin-dependent kinase 1 |
affects expression increases expression |
ISO |
Dinitrochlorobenzene affects the expression of CDK1 mRNA Dinitrochlorobenzene results in increased expression of CDK1 mRNA |
CTD |
PMID:21404309 PMID:22302311 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk12 |
cyclin-dependent kinase 12 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CDK12 mRNA |
CTD |
PMID:25236440 |
|
NCBI chr10:83,201,177...83,256,906
Ensembl chr10:83,201,211...83,280,888 Ensembl chr10:83,201,211...83,280,888
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CDKN1A mRNA |
CTD |
PMID:16314067 PMID:21404309 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
increases expression decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CDKN1C mRNA Dinitrochlorobenzene results in decreased expression of CDKN1C mRNA |
CTD |
PMID:20146380 PMID:21404309 |
|
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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G |
Cebpz |
CCAAT/enhancer binding protein zeta |
affects binding |
ISO |
Dinitrochlorobenzene binds to CEBPZ protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:16,119,871...16,137,600
Ensembl chr 6:16,119,872...16,137,600
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G |
Celf1 |
CUGBP, Elav-like family member 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CELF1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
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G |
Cerkl |
ceramide kinase-like |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CERKL mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 3:64,238,714...64,344,695
Ensembl chr 3:64,237,522...64,340,675
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G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CES1 mRNA |
CTD |
PMID:19524605 |
|
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Cfap91 |
cilia and flagella associated protein 91 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MAATS1 protein |
CTD |
PMID:32991956 |
|
NCBI chr11:62,413,613...62,457,281
Ensembl chr11:62,413,602...62,457,293
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G |
Chd3 |
chromodomain helicase DNA binding protein 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CHD3 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
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Chd4 |
chromodomain helicase DNA binding protein 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CHD4 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
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Chd5 |
chromodomain helicase DNA binding protein 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CHD5 protein |
CTD |
PMID:32991956 |
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NCBI chr 5:162,848,273...162,898,997
Ensembl chr 5:162,848,394...162,896,291
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Chid1 |
chitinase domain containing 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CHID1 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606
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Cidec |
cell death-inducing DFFA-like effector c |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CIDEC mRNA |
CTD |
PMID:17374397 |
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NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Cisd1 |
CDGSH iron sulfur domain 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CISD1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
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G |
Clasp1 |
cytoplasmic linker associated protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CLASP1 protein |
CTD |
PMID:32991956 |
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NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
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G |
Clec5a |
C-type lectin domain containing 5A |
increases expression affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of CLEC5A protein Dinitrochlorobenzene affects the expression of CLEC5A mRNA |
CTD |
PMID:33774146 |
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NCBI chr 4:69,407,125...69,416,872
Ensembl chr 4:69,407,835...69,416,859
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Clic1 |
chloride intracellular channel 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CLIC1 protein |
CTD |
PMID:32991956 |
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NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
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Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CLIC4 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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G |
Cln8 |
CLN8, transmembrane ER and ERGIC protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to CLN8 protein |
CTD |
PMID:32991956 |
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NCBI chr16:74,749,662...74,759,553
Ensembl chr16:74,749,662...74,759,774
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G |
Cmpk2 |
cytidine/uridine monophosphate kinase 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CMPK2 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
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G |
Cnn3 |
calponin 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CNN3 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104
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G |
Cnot1 |
CCR4-NOT transcription complex, subunit 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CNOT1 protein |
CTD |
PMID:32991956 |
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NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574
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G |
Cnot9 |
CCR4-NOT transcription complex subunit 9 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CNOT9 protein |
CTD |
PMID:32991956 |
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NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100
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G |
Cog4 |
component of oligomeric golgi complex 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to COG4 protein |
CTD |
PMID:32991956 |
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NCBI chr19:38,820,478...38,854,803
Ensembl chr19:38,820,501...38,854,796
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G |
Commd3 |
COMM domain containing 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of COMMD3 mRNA |
CTD |
PMID:21404309 |
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NCBI chr17:81,327,444...81,331,191
Ensembl chr17:81,327,405...81,331,177
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G |
Cope |
COPI coat complex subunit epsilon |
affects binding |
ISO |
Dinitrochlorobenzene binds to COPE protein |
CTD |
PMID:32991956 |
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NCBI chr16:19,114,871...19,125,076
Ensembl chr16:19,114,871...19,128,907
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to COX4I1 protein |
CTD |
PMID:32991956 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cphx1 |
cytoplasmic polyadenylated homeobox 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CPHX1 mRNA |
CTD |
PMID:22302311 |
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NCBI chr16:1,533,883...1,537,248
Ensembl chr16:1,528,440...1,537,082
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G |
Cpne3 |
copine 3 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CPNE3 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934
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G |
Creb1 |
cAMP responsive element binding protein 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CREB1 mRNA |
CTD |
PMID:20385217 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crem |
cAMP responsive element modulator |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CREM mRNA |
CTD |
PMID:17374397 PMID:19371601 |
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NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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G |
Crkl |
CRK like proto-oncogene, adaptor protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to CRKL protein |
CTD |
PMID:32991956 |
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NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
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G |
Crocc |
ciliary rootlet coiled-coil, rootletin |
affects binding |
ISO |
Dinitrochlorobenzene binds to CROCC protein |
CTD |
PMID:32991956 |
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NCBI chr 5:153,320,962...153,363,734
Ensembl chr 5:153,320,962...153,363,578
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G |
Csf2 |
colony stimulating factor 2 |
increases expression increases secretion |
ISO |
Dinitrochlorobenzene results in increased expression of CSF2 mRNA Dinitrochlorobenzene results in increased secretion of CSF2 protein |
CTD |
PMID:18652873 PMID:22245253 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf2ra |
colony stimulating factor 2 receptor subunit alpha |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CSF2RA mRNA |
CTD |
PMID:19647056 |
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NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128
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G |
Csf2rb |
colony stimulating factor 2 receptor subunit beta |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CSF2RB mRNA; Dinitrochlorobenzene results in increased expression of CSF2RB2 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157
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G |
Csf3 |
colony stimulating factor 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CSF3 mRNA |
CTD |
PMID:18652873 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Csf3r |
colony stimulating factor 3 receptor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CSF3R mRNA |
CTD |
PMID:19647056 |
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NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
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G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of CTLA4 mRNA |
CTD |
PMID:22302311 |
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NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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G |
Ctnna1 |
catenin alpha 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CTNNA1 protein |
CTD |
PMID:32991956 |
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NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
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G |
Ctnna2 |
catenin alpha 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CTNNA2 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:109,294,249...110,443,409
Ensembl chr 4:109,293,978...110,443,522
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G |
Ctnnbl1 |
catenin, beta like 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CTNNBL1 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:146,387,940...146,548,987
Ensembl chr 3:146,387,889...146,548,987
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G |
Ctps2 |
CTP synthase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CTPS2 protein |
CTD |
PMID:32991956 |
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NCBI chr X:31,645,873...31,786,733
Ensembl chr X:31,645,873...31,786,733
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G |
Ctsb |
cathepsin B |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of CTSB mRNA Dinitrochlorobenzene binds to CTSB protein |
CTD |
PMID:16314067 PMID:32991956 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsc |
cathepsin C |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CTSC mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
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G |
Ctsl |
cathepsin L |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CTSL mRNA |
CTD |
PMID:17374397 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Cul1 |
cullin 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to CUL1 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
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G |
Cul4a |
cullin 4A |
affects binding |
ISO |
Dinitrochlorobenzene binds to CUL4A protein |
CTD |
PMID:32991956 |
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NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA |
CTD |
PMID:20146380 PMID:20713136 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression affects expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL10 mRNA Dinitrochlorobenzene affects the expression of CXCL10 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA] |
CTD |
PMID:19647056 PMID:20146380 PMID:21404309 PMID:28219650 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
increases expression decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL14 mRNA Dinitrochlorobenzene results in decreased expression of CXCL14 protein |
CTD |
PMID:19647056 PMID:31734321 |
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NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
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G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CXCL16 mRNA |
CTD |
PMID:21404309 |
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NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL2 mRNA Dinitrochlorobenzene results in increased expression of CXCL2 mRNA; Dinitrochlorobenzene results in increased expression of CXCL2 protein |
CTD |
PMID:16675337 PMID:19647056 PMID:20146380 PMID:23178550 PMID:28826779 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL1 mRNA NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA] |
CTD |
PMID:19647056 PMID:20146380 PMID:20713136 PMID:21404309 PMID:28219650 PMID:28826779 More...
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCL9 mRNA |
CTD |
PMID:21404309 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCR1 protein |
CTD |
PMID:33774146 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCR2 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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G |
Cxcr3 |
C-X-C motif chemokine receptor 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CXCR3 protein |
CTD |
PMID:33774146 |
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NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
decreases expression increases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CXCR4 mRNA Dinitrochlorobenzene results in increased expression of CXCR4 mRNA |
CTD |
PMID:17374397 PMID:19371601 PMID:19647056 PMID:20146380 PMID:28219650 |
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NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cxcr6 |
C-X-C motif chemokine receptor 6 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of CXCR6 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CYP1A1 mRNA |
CTD |
PMID:20491607 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cytip |
cytohesin 1 interacting protein |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of CYTIP mRNA |
CTD |
PMID:17374397 PMID:19371601 |
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NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DACT1 mRNA |
CTD |
PMID:18242016 |
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NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
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G |
Dap3 |
death associated protein 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DAP3 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461
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G |
Dcps |
decapping enzyme, scavenger |
affects binding |
ISO |
Dinitrochlorobenzene binds to DCPS protein |
CTD |
PMID:32991956 |
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NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389
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G |
Dctpp1 |
dCTP pyrophosphatase 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DCTPP1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions increases expression |
ISO |
Glutathione inhibits the reaction [Dinitrochlorobenzene results in increased expression of DDIT3 mRNA] |
CTD |
PMID:17171638 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx1 |
DEAD-box helicase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DDX1 protein |
CTD |
PMID:32991956 |
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NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
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G |
Ddx18 |
DEAD-box helicase 18 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DDX18 protein |
CTD |
PMID:32991956 |
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NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161
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G |
Ddx52 |
DExD-box helicase 52 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DDX52 protein |
CTD |
PMID:32991956 |
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NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266
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G |
Ddx56 |
DEAD-box helicase 56 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DDX56 protein |
CTD |
PMID:32991956 |
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NCBI chr14:81,112,008...81,122,331
Ensembl chr14:81,112,012...81,122,333
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G |
Dhps |
deoxyhypusine synthase |
affects binding |
ISO |
Dinitrochlorobenzene binds to DHPS protein |
CTD |
PMID:32991956 |
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NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
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G |
Dhx36 |
DEAH-box helicase 36 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DHX36 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
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G |
Dhx9 |
DExH-box helicase 9 |
increases metabolic processing affects binding |
ISO |
Dinitrochlorobenzene results in increased metabolism of DHX9 protein Dinitrochlorobenzene binds to DHX9 protein |
CTD |
PMID:29267982 PMID:32991956 |
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NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
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G |
Diaph1 |
diaphanous-related formin 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DIAPH1 protein |
CTD |
PMID:32991956 |
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NCBI chr18:29,669,659...29,769,070
Ensembl chr18:29,669,659...29,769,172
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G |
Dkc1 |
dyskerin pseudouridine synthase 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DKC1 mRNA |
CTD |
PMID:17374397 |
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G |
Dld |
dihydrolipoamide dehydrogenase |
affects binding |
ISO |
Dinitrochlorobenzene binds to DLD protein |
CTD |
PMID:32991956 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlgap5 |
DLG associated protein 5 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DLGAP5 mRNA |
CTD |
PMID:17374397 |
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NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA] |
CTD |
PMID:23999411 PMID:27965148 |
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NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of DNAJB6 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
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G |
Dnmt1 |
DNA methyltransferase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DNMT1 protein |
CTD |
PMID:32991956 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DNMT3B mRNA |
CTD |
PMID:25236440 |
|
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
|
|
G |
Dock5 |
dedicator of cytokinesis 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DOCK5 protein |
CTD |
PMID:32991956 |
|
NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
|
|
G |
Dpyd |
dihydropyrimidine dehydrogenase |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DPYD mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
|
|
G |
Dpysl2 |
dihydropyrimidinase-like 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DPYSL2 protein |
CTD |
PMID:32991956 |
|
NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
|
|
G |
Dse |
dermatan sulfate epimerase |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of DSE mRNA |
CTD |
PMID:17374397 |
|
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
|
|
G |
Dtymk |
deoxythymidylate kinase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of DTYMK mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of DUSP1 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr10:16,680,478...16,683,275
|
|
G |
Dusp3 |
dual specificity phosphatase 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to DUSP3 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
|
|
G |
Dusp4 |
dual specificity phosphatase 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of DUSP4 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
|
|
G |
Dut |
deoxyuridine triphosphatase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of DUT mRNA |
CTD |
PMID:18242016 PMID:21404309 |
|
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
|
|
G |
E2f1 |
E2F transcription factor 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of E2F1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
|
|
G |
Ecd |
ecdysoneless cell cycle regulator |
affects binding |
ISO |
Dinitrochlorobenzene binds to ECD protein |
CTD |
PMID:32991956 |
|
NCBI chr15:3,967,209...3,998,713
Ensembl chr15:3,967,382...3,998,706
|
|
G |
Ecpas |
Ecm29 proteasome adaptor and scaffold |
affects binding |
ISO |
Dinitrochlorobenzene binds to ECPAS protein |
CTD |
PMID:32991956 |
|
NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
|
|
G |
Eef1a2 |
eukaryotic translation elongation factor 1 alpha 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to EEF1A2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
|
|
G |
Egf |
epidermal growth factor |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of EGF mRNA |
CTD |
PMID:20146380 |
|
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
|
|
G |
Egfr |
epidermal growth factor receptor |
affects binding |
ISO |
Dinitrochlorobenzene binds to EGFR protein |
CTD |
PMID:32991956 |
|
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
|
|
G |
Egr2 |
early growth response 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of EGR2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
|
|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of EHHADH mRNA |
CTD |
PMID:17374397 |
|
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
|
|
G |
Eif3a |
eukaryotic translation initiation factor 3, subunit A |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of EIF3A protein |
CTD |
PMID:29267982 |
|
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
|
|
G |
Eif3g |
eukaryotic translation initiation factor 3, subunit G |
affects binding |
ISO |
Dinitrochlorobenzene binds to EIF3G protein |
CTD |
PMID:32991956 |
|
NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808
|
|
G |
Eif4b |
eukaryotic translation initiation factor 4B |
affects binding |
ISO |
Dinitrochlorobenzene binds to EIF4B protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:133,206,637...133,228,436
|
|
G |
Eif4g3 |
eukaryotic translation initiation factor 4 gamma, 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to EIF4G3 protein |
CTD |
PMID:32991956 |
|
NCBI chr 5:150,197,410...150,418,862
Ensembl chr 5:150,195,226...150,418,363
|
|
G |
Elac2 |
elaC ribonuclease Z 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ELAC2 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:49,632,308...49,655,614
Ensembl chr10:49,632,378...49,655,614
|
|
G |
Elavl1 |
ELAV like RNA binding protein 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ELAVL1 protein |
CTD |
PMID:21969073 |
|
NCBI chr12:2,640,936...2,684,787
Ensembl chr12:2,645,061...2,684,784
|
|
G |
Elmod2 |
ELMO domain containing 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ELMOD2 protein |
CTD |
PMID:32991956 |
|
NCBI chr19:24,786,166...24,805,626
Ensembl chr19:24,786,241...24,805,130
|
|
G |
Emb |
embigin |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of EMB mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050
|
|
G |
Emd |
emerin |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of EMD mRNA |
CTD |
PMID:19527780 |
|
NCBI chr X:152,038,990...152,042,190
Ensembl chr X:152,038,998...152,045,807
|
|
G |
Epor |
erythropoietin receptor |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of EPOR mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
|
|
G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to EPRS1 protein |
CTD |
PMID:32991956 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
|
|
G |
Ercc6 |
ERCC excision repair 6, chromatin remodeling factor |
affects binding |
ISO |
Dinitrochlorobenzene binds to ERCC6 protein |
CTD |
PMID:32991956 |
|
NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
|
|
G |
Ercc6l |
ERCC excision repair 6 like, spindle assembly checkpoint helicase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ERCC6L mRNA |
CTD |
PMID:18242016 |
|
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
|
|
G |
Esd |
esterase D |
affects binding |
ISO |
Dinitrochlorobenzene binds to ESD protein |
CTD |
PMID:32991956 |
|
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
|
|
G |
Esr1 |
estrogen receptor 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of ESR1 mRNA |
CTD |
PMID:19527780 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Esyt2 |
extended synaptotagmin 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ESYT2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590
|
|
G |
Evpl |
envoplakin |
affects binding |
ISO |
Dinitrochlorobenzene binds to EVPL protein |
CTD |
PMID:32991956 |
|
NCBI chr10:101,458,227...101,474,778
Ensembl chr10:101,458,216...101,474,763
|
|
G |
Exoc1 |
exocyst complex component 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to EXOC1 protein |
CTD |
PMID:32991956 |
|
NCBI chr14:31,611,536...31,659,920
Ensembl chr14:31,611,547...31,659,914
|
|
G |
Exoc6b |
exocyst complex component 6B |
affects binding |
ISO |
Dinitrochlorobenzene binds to EXOC6B protein |
CTD |
PMID:32991956 |
|
NCBI chr 4:117,094,741...117,550,221
Ensembl chr 4:117,094,741...117,550,180
|
|
G |
Ezr |
ezrin |
affects binding |
ISO |
Dinitrochlorobenzene binds to EZR protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
|
|
G |
F13a1 |
coagulation factor XIII A1 chain |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of F13A1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
|
|
G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of FABP1 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
|
|
G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of FABP7 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
|
|
G |
Fam3c |
FAM3 metabolism regulating signaling molecule C |
affects binding |
ISO |
Dinitrochlorobenzene binds to FAM3C protein |
CTD |
PMID:32991956 |
|
NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
|
|
G |
Fam76b |
family with sequence similarity 76, member B |
affects binding |
ISO |
Dinitrochlorobenzene binds to FAM76B protein |
CTD |
PMID:32991956 |
|
NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861
|
|
G |
Farsa |
phenylalanyl-tRNA synthetase subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to FARSA protein |
CTD |
PMID:32991956 |
|
NCBI chr19:23,291,409...23,300,985
Ensembl chr19:23,268,869...23,300,980
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|
G |
Fasn |
fatty acid synthase |
affects binding |
ISO |
Dinitrochlorobenzene binds to FASN protein |
CTD |
PMID:32991956 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
|
|
G |
Fbxo9 |
f-box protein 9 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of FBXO9 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
|
|
G |
Fech |
ferrochelatase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FECH mRNA |
CTD |
PMID:20566472 |
|
NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
|
|
G |
Ferry3 |
FERRY endosomal RAB5 effector complex subunit 3 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of FERRY3 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382
|
|
G |
Ffar2 |
free fatty acid receptor 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FFAR2 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033
|
|
G |
Fgf9 |
fibroblast growth factor 9 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FGF9 mRNA |
CTD |
PMID:20146380 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
|
|
G |
Fgfr3 |
fibroblast growth factor receptor 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to FGFR3 protein |
CTD |
PMID:32991956 |
|
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
|
|
G |
Fgl2 |
fibrinogen-like 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of FGL2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
|
|
G |
Fkbp8 |
FKBP prolyl isomerase 8 |
affects binding |
ISO |
Dinitrochlorobenzene binds to FKBP8 protein |
CTD |
PMID:32991956 |
|
NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
|
|
G |
Flna |
filamin A |
affects binding |
ISO |
Dinitrochlorobenzene binds to FLNA protein |
CTD |
PMID:32991956 |
|
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
|
|
G |
Flnb |
filamin B |
affects binding |
ISO |
Dinitrochlorobenzene binds to FLNB protein |
CTD |
PMID:32991956 |
|
NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FOS mRNA |
CTD |
PMID:20146380 PMID:25236440 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FOSL1 mRNA |
CTD |
PMID:25236440 |
|
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
|
|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FOSL2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
|
|
G |
Frmd7 |
FERM domain containing 7 |
affects binding |
ISO |
Dinitrochlorobenzene binds to FRMD7 protein |
CTD |
PMID:32991956 |
|
NCBI chr X:130,375,925...130,423,836
Ensembl chr X:130,377,227...130,423,771
|
|
G |
Fscn1 |
fascin actin-bundling protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to FSCN1 protein |
CTD |
PMID:32991956 |
|
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
|
|
G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FTH1 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
|
|
G |
Ftl1 |
ferritin light chain 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of FTL mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
|
|
G |
Fxyd4 |
FXYD domain-containing ion transport regulator 4 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of FXYD4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:151,109,779...151,113,637
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of G6PD mRNA |
CTD |
PMID:20566472 |
|
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
|
|
G |
Gal3st1 |
galactose-3-O-sulfotransferase 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of GAL3ST1 mRNA |
CTD |
PMID:19527780 |
|
NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
|
|
G |
Gars1 |
glycyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GARS1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
|
|
G |
Gart |
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
affects binding |
ISO |
Dinitrochlorobenzene binds to GART protein |
CTD |
PMID:32991956 |
|
NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GCLC mRNA |
CTD |
PMID:20146380 PMID:20566472 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of GCLM mRNA NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] |
CTD |
PMID:20146380 PMID:20566472 PMID:23999411 PMID:27965148 |
|
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
|
|
G |
Gdi2 |
GDP dissociation inhibitor 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GDI2 protein |
CTD |
PMID:32991956 |
|
NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366
|
|
G |
Glyr1 |
glyoxylate reductase 1 homolog |
affects binding |
ISO |
Dinitrochlorobenzene binds to GLYR1 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:10,532,036...10,567,639
Ensembl chr10:10,532,154...10,567,637
|
|
G |
Gmpr |
guanosine monophosphate reductase |
increases methylation |
ISO |
Dinitrochlorobenzene results in increased methylation of GMPR gene |
CTD |
PMID:26732893 |
|
NCBI chr17:19,151,820...19,189,626
Ensembl chr17:19,151,815...19,189,621
|
|
G |
Gmps |
guanine monophosphate synthase |
affects binding |
ISO |
Dinitrochlorobenzene binds to GMPS protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
|
|
G |
Golga2 |
golgin A2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GOLGA2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
|
|
G |
Golgb1 |
golgin B1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GOLGB1 protein |
CTD |
PMID:32991956 |
|
NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
|
|
G |
Gon4l |
gon-4 like |
affects binding |
ISO |
Dinitrochlorobenzene binds to GON4L protein |
CTD |
PMID:32991956 |
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NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of GPAT3 mRNA |
CTD |
PMID:33774146 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GPD2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
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G |
Gpi |
glucose-6-phosphate isomerase |
affects binding |
ISO |
Dinitrochlorobenzene binds to GPI protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
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G |
Gpnmb |
glycoprotein nmb |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GPNMB mRNA |
CTD |
PMID:16314067 |
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NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
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G |
Gpx1 |
glutathione peroxidase 1 |
affects expression multiple interactions |
ISO |
Dinitrochlorobenzene affects the expression of GPX1 mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA] |
CTD |
PMID:28219650 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
affects expression multiple interactions |
ISO |
Dinitrochlorobenzene affects the expression of GPX2 mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA] |
CTD |
PMID:28219650 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GPX3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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G |
Gpx5 |
glutathione peroxidase 5 |
multiple interactions affects expression |
ISO |
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA] Dinitrochlorobenzene affects the expression of GPX5 mRNA |
CTD |
PMID:28219650 |
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NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074
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G |
Gpx6 |
glutathione peroxidase 6 |
multiple interactions affects expression |
ISO |
NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA] Dinitrochlorobenzene affects the expression of GPX6 mRNA |
CTD |
PMID:28219650 |
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NCBI chr17:43,408,472...43,416,091
Ensembl chr17:43,408,472...43,416,091
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G |
Gpx7 |
glutathione peroxidase 7 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of GPX7 mRNA |
CTD |
PMID:28219650 |
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NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004
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G |
Grap2 |
GRB2-related adaptor protein 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GRAP2 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GREM1 mRNA |
CTD |
PMID:20146380 |
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NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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G |
Grsf1 |
G-rich RNA sequence binding factor 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GRSF1 protein |
CTD |
PMID:32991956 |
|
NCBI chr14:19,412,944...19,429,364
Ensembl chr14:19,412,156...19,429,362
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GSK3B mRNA |
CTD |
PMID:17374397 PMID:28219650 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of GSR mRNA NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA] |
CTD |
PMID:20566472 PMID:28219650 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions increases metabolic processing increases expression |
ISO EXP |
[GSTA1 protein binds to GSTA1 protein] which affects the metabolism of Dinitrochlorobenzene; [GSTA1 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene; GSTA1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]; GSTA1 protein binds to and affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione] GSTA1 protein results in increased metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTA1 protein |
CTD |
PMID:3138230 PMID:9794801 PMID:11851347 PMID:12147362 PMID:14690442 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases metabolic processing decreases metabolic processing |
ISO |
GSTA2 protein results in increased metabolism of Dinitrochlorobenzene GSTA2 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene |
CTD |
PMID:3138230 PMID:15077012 PMID:15128049 |
|
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
increases expression |
EXP |
Dinitrochlorobenzene results in increased expression of GSTA3 protein |
CTD |
PMID:9794801 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
multiple interactions affects metabolic processing affects binding |
ISO EXP |
[GSTA1 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene; [GSTA4 protein binds to GSTA4 protein] which affects the metabolism of Dinitrochlorobenzene GSTA4 protein affects the metabolism of Dinitrochlorobenzene 1-chloro-2 4-dinitrobenzene binds to Gsta4 protein |
CTD RGD |
PMID:2619714 PMID:11851347 PMID:11018474 |
RGD:1641942 |
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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G |
Gstm1 |
glutathione S-transferase mu 1 |
affects metabolic processing affects binding multiple interactions affects expression increases glutathionylation decreases expression |
ISO EXP |
GSTM1 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene binds to GSTM1 protein GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog] Dinitrochlorobenzene affects the expression of GSTM1 mRNA GSTM1 protein results in increased glutathionylation of Dinitrochlorobenzene Dinitrochlorobenzene results in decreased expression of GSTM1 mRNA |
CTD |
PMID:2904809 PMID:3570286 PMID:9545290 PMID:12069689 PMID:21404309 PMID:22085405 PMID:28219650 PMID:28762043 More...
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
Gstm2 |
glutathione S-transferase mu 2 |
affects metabolic processing affects activity multiple interactions increases expression |
ISO EXP |
GSTM2 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene affects the activity of GSTM2 protein Dinitrochlorobenzene promotes the reaction [GSTM2 protein affects the metabolism of Glutathione] Dinitrochlorobenzene results in increased expression of GSTM2 protein GSTM5 protein affects the metabolism of Dinitrochlorobenzene |
CTD |
PMID:3570286 PMID:9545290 PMID:9794801 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstm4 |
glutathione S-transferase mu 4 |
multiple interactions affects metabolic processing |
ISO |
GSTM4 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione] GSTM4 protein affects the metabolism of Dinitrochlorobenzene |
CTD |
PMID:8203914 PMID:8349586 |
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NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
increases metabolic processing decreases metabolic processing affects metabolic processing increases expression decreases expression |
ISO EXP |
GSTM3 protein polymorphism results in increased metabolism of Dinitrochlorobenzene GSTM3 protein polymorphism results in decreased metabolism of Dinitrochlorobenzene GSTM3 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTM3 protein Dinitrochlorobenzene results in decreased expression of GSTM3 mRNA |
CTD |
PMID:3169012 PMID:9545290 PMID:9794801 PMID:15247628 PMID:21404309 |
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NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
Gstm5l |
glutathione S-transferase, mu 5-like |
affects metabolic processing |
EXP |
GSTM5 protein affects the metabolism of Dinitrochlorobenzene |
CTD |
PMID:9545290 |
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NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstp1 |
glutathione S-transferase pi 1 |
affects metabolic processing increases expression decreases activity multiple interactions affects binding decreases response to substance increases activity |
ISO EXP |
GSTP1 protein affects the metabolism of Dinitrochlorobenzene; GSTP2 protein affects the metabolism of Dinitrochlorobenzene Dinitrochlorobenzene results in increased expression of GSTP1 protein Dinitrochlorobenzene results in decreased activity of GSTP1 protein GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene; Mercuric Chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; methylmercuric chloride inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]; Sodium Selenite inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene] 1-chloro-2,4-dinitrobenzene binds to Gstp1 protein GSTP1 protein mutant form results in decreased susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene results in increased activity of GSTP1 protein mutant form |
CTD RGD |
PMID:2619714 PMID:3570286 PMID:9794801 PMID:10870112 PMID:15355982 PMID:22401947 PMID:37031912 PMID:11018474 More...
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RGD:1641942 |
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of GSTT1 mRNA |
CTD |
PMID:28219650 |
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NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Gstt2 |
glutathione S-transferase theta 2 |
increases metabolic processing |
EXP |
GSTT2 protein results in increased metabolism of Dinitrochlorobenzene |
CTD |
PMID:12054768 |
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NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
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G |
Gstz1 |
glutathione S-transferase zeta 1 |
affects metabolic processing |
ISO |
GSTZ1 protein affects the metabolism of Dinitrochlorobenzene |
CTD |
PMID:1846734 |
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NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
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G |
Gtf2b |
general transcription factor IIB |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GTF2B mRNA |
CTD |
PMID:17374397 |
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NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
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G |
Gtf2i |
general transcription factor II I |
affects binding |
ISO |
Dinitrochlorobenzene binds to GTF2I protein |
CTD |
PMID:32991956 |
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NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243
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G |
Gyg1 |
glycogenin 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to GYG1 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:102,611,888...102,653,916
Ensembl chr 2:102,598,496...102,653,797
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G |
Gzma |
granzyme A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of GZMA mRNA |
CTD |
PMID:18242016 |
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NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
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G |
Gzmb |
granzyme B |
affects expression increases expression |
ISO EXP |
Dinitrochlorobenzene affects the expression of GZMB mRNA Dinitrochlorobenzene results in increased expression of GZMB mRNA |
CTD |
PMID:18652873 PMID:21893156 PMID:22302311 |
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NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to HADHA protein |
CTD |
PMID:32991956 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Has1 |
hyaluronan synthase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HAS1 mRNA; Dinitrochlorobenzene results in increased expression of HAS1 protein |
CTD |
PMID:31226360 |
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NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397
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G |
Has2 |
hyaluronan synthase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HAS2 mRNA; Dinitrochlorobenzene results in increased expression of HAS2 protein |
CTD |
PMID:31226360 |
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NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933
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G |
Has3 |
hyaluronan synthase 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HAS3 mRNA; Dinitrochlorobenzene results in increased expression of HAS3 protein |
CTD |
PMID:31226360 |
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NCBI chr19:34,768,421...34,782,170
Ensembl chr19:34,771,982...34,782,592
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G |
Hbb |
hemoglobin subunit beta |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of HBB protein |
CTD |
PMID:29267982 |
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NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hdlbp |
high density lipoprotein binding protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to HDLBP protein |
CTD |
PMID:32991956 |
|
NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
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G |
Heatr1 |
HEAT repeat containing 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HEATR1 protein |
CTD |
PMID:32991956 |
|
NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948
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G |
Heatr5b |
HEAT repeat containing 5B |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of HEATR5B mRNA |
CTD |
PMID:17374397 |
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NCBI chr 6:16,243,424...16,323,444
Ensembl chr 6:16,243,461...16,323,435
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G |
Hebp2 |
heme binding protein 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HEBP2 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777
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G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HECTD4 protein |
CTD |
PMID:32991956 |
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NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
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G |
Hexa |
hexosaminidase subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to HEXA protein |
CTD |
PMID:32991956 |
|
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
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G |
Hipk2 |
homeodomain interacting protein kinase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HIPK2 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
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G |
Hist1h4m |
histone cluster 1, H4m |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of H4C1 protein |
CTD |
PMID:29267982 |
|
NCBI chr17:42,698,016...42,698,420
Ensembl chr17:42,698,025...42,698,958
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G |
Hmgb1 |
high mobility group box 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of HMGB1 mRNA |
CTD |
PMID:28219650 |
|
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; BACH1 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA] |
CTD |
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20566472 PMID:20713136 PMID:25236440 PMID:26244607 PMID:28219650 PMID:31967339 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of HNRNPA3 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
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G |
Hnrnpc |
heterogeneous nuclear ribonucleoprotein C |
affects binding |
ISO |
Dinitrochlorobenzene binds to HNRNPC protein |
CTD |
PMID:32991956 |
|
NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183
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G |
Hnrnpll |
heterogeneous nuclear ribonucleoprotein L-like |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HNRNPLL mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 6:14,969,953...15,000,574
Ensembl chr 6:14,970,057...14,999,745
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HSD17B4 protein |
CTD |
PMID:32991956 |
|
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of HSPA1A protein |
CTD |
PMID:29267982 |
|
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HSPA2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HSPA6 mRNA |
CTD |
PMID:16314067 PMID:23999411 |
|
NCBI chr13:83,273,176...83,274,317
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases metabolic processing affects binding |
ISO |
Dinitrochlorobenzene results in increased metabolism of HSPA8 protein Dinitrochlorobenzene binds to HSPA8 protein |
CTD |
PMID:29267982 PMID:32991956 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HSPB1 protein |
CTD |
PMID:32991956 |
|
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HSPD1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to HSPH1 protein |
CTD |
PMID:32991956 |
|
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Hyal1 |
hyaluronidase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of HYAL1 mRNA |
CTD |
PMID:31226360 |
|
NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210
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G |
Iars1 |
isoleucyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IARS1 protein |
CTD |
PMID:32991956 |
|
NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression multiple interactions affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of ICAM1 mRNA; Dinitrochlorobenzene results in increased expression of ICAM1 protein Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; cariporide inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Citric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Hydrochloric Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Lactic Acid inhibits the reaction [Dinitrochlorobenzene results in increased expression of ICAM1 protein]; Potassium Chloride affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein] |
CTD |
PMID:15737199 PMID:19427879 PMID:20417223 PMID:21742781 PMID:29743441 PMID:30842373 PMID:33774146 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ID2 mRNA |
CTD |
PMID:20146380 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Ide |
insulin degrading enzyme |
affects binding |
ISO |
Dinitrochlorobenzene binds to IDE protein |
CTD |
PMID:32991956 |
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NCBI chr 1:235,002,984...235,102,448
Ensembl chr 1:234,995,351...235,102,440
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G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of IDI1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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G |
Ier3 |
immediate early response 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IER3 mRNA |
CTD |
PMID:17374397 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ifi27 |
interferon, alpha-inducible protein 27 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IFI27 mRNA |
CTD |
PMID:18242016 |
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NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
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G |
Ifi44l |
interferon-induced protein 44-like |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IFI44L mRNA |
CTD |
PMID:18242016 |
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NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of IFIT2 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
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G |
Ifng |
interferon gamma |
multiple interactions increases secretion increases expression decreases expression |
ISO EXP |
4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IFNG protein] Dinitrochlorobenzene results in increased secretion of IFNG protein Dinitrochlorobenzene results in increased expression of IFNG mRNA; Dinitrochlorobenzene results in increased expression of IFNG protein Dinitrochlorobenzene results in decreased expression of IFNG mRNA |
CTD |
PMID:10637130 PMID:11708898 PMID:12202904 PMID:12884401 PMID:15588915 PMID:15588918 PMID:18242016 PMID:18652873 PMID:19042193 PMID:19422874 PMID:21404309 PMID:22245253 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:25449201 PMID:28219650 PMID:29233007 PMID:30017638 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IFRD1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
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G |
Igbp1 |
immunoglobulin binding protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IGBP1 protein |
CTD |
PMID:32991956 |
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NCBI chr X:65,582,832...65,605,078
Ensembl chr X:65,582,821...65,606,049
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IGFBP6 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966
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G |
Il10 |
interleukin 10 |
increases expression multiple interactions affects expression decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL10 protein [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL10 protein] Dinitrochlorobenzene affects the expression of IL10 mRNA Dinitrochlorobenzene results in decreased expression of IL10 mRNA; Dinitrochlorobenzene results in decreased expression of IL10 protein |
CTD |
PMID:19422874 PMID:23499868 PMID:28219650 PMID:29233007 PMID:34651546 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL10RA mRNA |
CTD |
PMID:19647056 |
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NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
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G |
Il11 |
interleukin 11 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL11 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il12a |
interleukin 12A |
increases expression decreases expression |
EXP ISO |
Dinitrochlorobenzene results in increased expression of IL12A mRNA Dinitrochlorobenzene results in decreased expression of IL12A mRNA |
CTD |
PMID:25449201 PMID:28219650 |
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NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
increases expression increases secretion affects expression decreases methylation increases methylation |
ISO EXP |
Dinitrochlorobenzene results in increased expression of IL12B mRNA; Dinitrochlorobenzene results in increased expression of IL12B protein Dinitrochlorobenzene results in increased secretion of IL12B protein Dinitrochlorobenzene affects the expression of IL12B mRNA Dinitrochlorobenzene results in decreased methylation of IL12B gene Dinitrochlorobenzene results in increased methylation of IL12B gene |
CTD |
PMID:10199581 PMID:11708898 PMID:18652873 PMID:22302311 PMID:25449201 PMID:26732893 PMID:28219650 More...
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb1 |
interleukin 12 receptor subunit beta 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL12RB1 mRNA |
CTD |
PMID:18242016 PMID:21404309 |
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NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
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G |
Il13 |
interleukin 13 |
multiple interactions increases expression |
ISO |
Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL13 protein] Dinitrochlorobenzene results in increased expression of IL13 mRNA; Dinitrochlorobenzene results in increased expression of IL13 protein |
CTD |
PMID:23133493 PMID:23200891 PMID:23454147 PMID:29233007 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO EXP |
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL17A mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL17A mRNA] |
CTD |
PMID:23133493 PMID:23499868 PMID:25449201 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
increases activity increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased activity of IL18 protein Dinitrochlorobenzene results in increased expression of IL18 mRNA Dinitrochlorobenzene results in increased expression of IL18 protein PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] |
CTD |
PMID:11708898 PMID:15840424 PMID:23063874 PMID:27585668 PMID:28389280 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il18r1 |
interleukin 18 receptor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL18R1 mRNA |
CTD |
PMID:11708898 |
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NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
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G |
Il19 |
interleukin 19 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL19 mRNA |
CTD |
PMID:19647056 |
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NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
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G |
Il1a |
interleukin 1 alpha |
increases activity increases expression multiple interactions affects secretion affects expression |
ISO |
Dinitrochlorobenzene results in increased activity of IL1A protein Dinitrochlorobenzene results in increased expression of IL1A mRNA; Dinitrochlorobenzene results in increased expression of IL1A protein Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] Dinitrochlorobenzene affects the secretion of IL1A protein Dinitrochlorobenzene affects the expression of IL1A mRNA |
CTD |
PMID:7476933 PMID:12781210 PMID:15840424 PMID:18652873 PMID:23178550 PMID:28219650 PMID:33715048 More...
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions increases secretion affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL1B mRNA; Dinitrochlorobenzene results in increased expression of IL1B protein Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA] Dinitrochlorobenzene results in increased secretion of IL1B protein Dinitrochlorobenzene affects the expression of IL1B mRNA [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein |
CTD |
PMID:11033066 PMID:16314067 PMID:16687389 PMID:18652873 PMID:19647056 PMID:20146380 PMID:21404309 PMID:24964617 PMID:28219650 PMID:28941582 PMID:30842373 PMID:33715048 PMID:33774146 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL1RL1 mRNA |
CTD |
PMID:11708898 PMID:20146380 |
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NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il2 |
interleukin 2 |
increases expression increases secretion |
ISO |
Dinitrochlorobenzene results in increased expression of IL2 mRNA; Dinitrochlorobenzene results in increased expression of IL2 protein Dinitrochlorobenzene results in increased secretion of IL2 protein |
CTD |
PMID:15588918 PMID:18652873 PMID:22245253 PMID:22381623 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il21 |
interleukin 21 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of IL21 mRNA |
CTD |
PMID:22302311 |
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NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
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G |
Il23a |
interleukin 23 subunit alpha |
increases expression |
EXP |
Dinitrochlorobenzene results in increased expression of IL23A mRNA |
CTD |
PMID:25449201 |
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NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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G |
Il24 |
interleukin 24 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL24 mRNA |
CTD |
PMID:19647056 |
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NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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G |
Il25 |
interleukin 25 |
increases methylation |
ISO |
Dinitrochlorobenzene results in increased methylation of IL25 gene; Dinitrochlorobenzene results in increased methylation of IL25 promoter |
CTD |
PMID:24675093 PMID:26732893 |
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NCBI chr15:28,408,766...28,412,157
Ensembl chr15:28,408,842...28,411,893
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
affects expression increases expression |
ISO |
Dinitrochlorobenzene affects the expression of IL2RA mRNA Dinitrochlorobenzene results in increased expression of IL2RA mRNA |
CTD |
PMID:21404309 PMID:22302311 |
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NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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G |
Il3 |
interleukin 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL3 mRNA |
CTD |
PMID:18652873 |
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NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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G |
Il31 |
interleukin 31 |
multiple interactions |
ISO |
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL31 mRNA] |
CTD |
PMID:23499868 |
|
NCBI chr12:33,095,108...33,105,026
Ensembl chr12:33,092,097...33,105,037
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G |
Il4 |
interleukin 4 |
affects expression multiple interactions increases expression decreases expression |
ISO |
Dinitrochlorobenzene affects the expression of IL4 mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL4 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of IL4 protein] Dinitrochlorobenzene results in increased expression of IL4 mRNA; Dinitrochlorobenzene results in increased expression of IL4 protein Dinitrochlorobenzene results in decreased expression of IL4 mRNA; Dinitrochlorobenzene results in decreased expression of IL4 protein |
CTD |
PMID:15588918 PMID:15664275 PMID:18652873 PMID:19422874 PMID:22302311 PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 PMID:28826779 PMID:29233007 PMID:34651546 More...
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il4r |
interleukin 4 receptor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL4RA mRNA; Dinitrochlorobenzene results in increased expression of IL4RA protein |
CTD |
PMID:19647056 PMID:22381623 |
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NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
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G |
Il5 |
interleukin 5 |
multiple interactions increases expression |
ISO |
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of IL5 mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA]; Prednisolone inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL5 mRNA] |
CTD |
PMID:23133493 PMID:23200891 PMID:23454147 PMID:23499868 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression increases secretion |
ISO |
[Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of IL6 mRNA; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of IL6 mRNA] Dinitrochlorobenzene results in increased expression of IL6 mRNA; Dinitrochlorobenzene results in increased expression of IL6 protein Dinitrochlorobenzene results in increased secretion of IL6 protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein |
CTD |
PMID:11378323 PMID:12202904 PMID:16687389 PMID:18652873 PMID:19647056 PMID:22245253 PMID:24964617 PMID:28941582 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il7 |
interleukin 7 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of IL7 mRNA |
CTD |
PMID:18242016 PMID:21404309 |
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NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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G |
Il7r |
interleukin 7 receptor |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IL7R mRNA |
CTD |
PMID:20713136 |
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NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
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G |
Ilf3 |
interleukin enhancer binding factor 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ILF3 protein |
CTD |
PMID:32991956 |
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NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
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G |
Inhba |
inhibin subunit beta A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of INHBA mRNA |
CTD |
PMID:19647056 |
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NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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G |
Ipcef1 |
interaction protein for cytohesin exchange factors 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of IPCEF1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:43,237,903...43,451,735
Ensembl chr 1:43,269,202...43,427,969
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G |
Ipo7 |
importin 7 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IPO7 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:164,062,702...164,102,938
Ensembl chr 1:164,062,702...164,102,938
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G |
Ipo8 |
importin 8 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IPO8 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:181,729,216...181,793,672
Ensembl chr 4:181,729,220...181,793,161
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G |
Ipo9 |
importin 9 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IPO9 protein |
CTD |
PMID:32991956 |
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NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IQGAP1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
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G |
Iqgap2 |
IQ motif containing GTPase activating protein 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to IQGAP2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
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G |
Irf1 |
interferon regulatory factor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of IRF1 mRNA |
CTD |
PMID:20146380 |
|
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Itgav |
integrin subunit alpha V |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of ITGAV mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Ivl |
involucrin |
affects binding |
ISO |
Dinitrochlorobenzene binds to IVL protein |
CTD |
PMID:32991956 |
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NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of JUN mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnj2 |
potassium inwardly-rectifying channel, subfamily J, member 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of KCNJ2 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions affects metabolic processing increases expression decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]; tetrachlorobenzoquinone promotes the reaction [Dinitrochlorobenzene promotes the reaction [KEAP1 protein binds to KEAP1 protein]] Dinitrochlorobenzene affects the metabolism of KEAP1 protein Dinitrochlorobenzene results in decreased expression of KEAP1 mRNA |
CTD |
PMID:18785192 PMID:19033392 PMID:25742418 PMID:28219650 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Kif23 |
kinesin family member 23 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of KIF23 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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G |
Kifc1 |
kinesin family member C1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KIFC1 protein |
CTD |
PMID:32991956 |
|
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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G |
Kitlg |
KIT ligand |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of KITL mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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G |
Klf6 |
KLF transcription factor 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of KLF6 mRNA |
CTD |
PMID:16314067 PMID:17374397 |
|
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Kpna2 |
karyopherin subunit alpha 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KPNA2 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
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G |
Krr1 |
KRR1, small subunit processome component homolog |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRR1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
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G |
Krt14 |
keratin 14 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT14 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
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G |
Krt16 |
keratin 16 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT16 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
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G |
Krt17 |
keratin 17 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT17 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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G |
Krt2 |
keratin 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:132,940,862...132,947,963
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G |
Krt4 |
keratin 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT4 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:133,046,067...133,052,027
Ensembl chr 7:133,046,515...133,052,019
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G |
Krt5 |
keratin 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT5 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850
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G |
Krt6c |
keratin 6c |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT6C protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:132,799,608...132,804,045
Ensembl chr 7:132,799,616...132,804,045
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G |
Krt73 |
keratin 73 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT73 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:132,927,812...132,936,323
Ensembl chr 7:132,928,256...132,936,280
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G |
Krt75 |
keratin 75 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT75 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
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G |
Krt76 |
keratin 76 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT76 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:133,016,990...133,025,475
Ensembl chr 7:133,016,992...133,025,496
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G |
Krt78 |
keratin 78 |
affects binding |
ISO |
Dinitrochlorobenzene binds to KRT78 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:133,074,193...133,081,536
Ensembl chr 7:133,074,215...133,082,021
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to LAMP2 protein |
CTD |
PMID:32991956 |
|
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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G |
Lgals7 |
galectin 7 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of LGALS7 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
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G |
Lig1 |
DNA ligase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of LIG1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
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G |
Lmna |
lamin A/C |
increases metabolic processing affects binding |
ISO |
Dinitrochlorobenzene results in increased metabolism of LMNA protein Dinitrochlorobenzene binds to LMNA protein |
CTD |
PMID:29267982 PMID:32991956 |
|
NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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G |
Lmnb2 |
lamin B2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to LMNB2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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G |
Ltb |
lymphotoxin beta |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of LTB mRNA |
CTD |
PMID:19647056 |
|
NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
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G |
Maff |
MAF bZIP transcription factor F |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MAFF mRNA |
CTD |
PMID:20491607 PMID:20566472 |
|
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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G |
Mafg |
MAF bZIP transcription factor G |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MAFG mRNA |
CTD |
PMID:20566472 |
|
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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G |
Mafk |
MAF bZIP transcription factor K |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MAFK mRNA |
CTD |
PMID:17374397 PMID:20566472 |
|
NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048 Ensembl chr12:14,833,984...14,837,048
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G |
Maip1 |
matrix AAA peptidase interacting protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MAIP1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 9:58,978,901...58,986,831
Ensembl chr 9:58,978,716...58,986,829
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MAP2K2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MAP3K1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein] |
CTD |
PMID:18495191 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk12 |
mitogen-activated protein kinase 12 |
decreases methylation |
ISO |
Dinitrochlorobenzene results in decreased methylation of MAPK12 promoter |
CTD |
PMID:24675093 |
|
NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation affects binding |
ISO |
Dinitrochlorobenzene results in increased phosphorylation of MAPK14 protein Dinitrochlorobenzene binds to MAPK14 protein |
CTD |
PMID:15737199 PMID:32991956 |
|
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions decreases phosphorylation |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]; SB 203580 inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein] |
CTD |
PMID:18495191 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Dinitrochlorobenzene results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:18495191 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MARCKS mRNA |
CTD |
PMID:16314067 |
|
NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Mccc2 |
methylcrotonyl-CoA carboxylase subunit 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MCCC2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972
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G |
Mcf2 |
MCF.2 cell line derived transforming sequence |
affects binding |
ISO |
Dinitrochlorobenzene binds to MCF2 protein |
CTD |
PMID:32991956 |
|
NCBI chr X:138,414,077...138,514,828
Ensembl chr X:138,409,256...138,514,446
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G |
Mcf2l |
MCF.2 cell line derived transforming sequence-like |
affects binding |
ISO |
Dinitrochlorobenzene binds to MCF2L protein |
CTD |
PMID:32991956 |
|
NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733
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G |
Mcm2 |
minichromosome maintenance complex component 2 |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of MCM2 mRNA Dinitrochlorobenzene binds to MCM2 protein |
CTD |
PMID:21404309 PMID:32991956 |
|
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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G |
Mcm3 |
minichromosome maintenance complex component 3 |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of MCM3 mRNA Dinitrochlorobenzene binds to MCM3 protein |
CTD |
PMID:21404309 PMID:32991956 |
|
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
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G |
Mcm4 |
minichromosome maintenance complex component 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MCM4 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144
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G |
Mcm5 |
minichromosome maintenance complex component 5 |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of MCM5 mRNA Dinitrochlorobenzene binds to MCM5 protein |
CTD |
PMID:21404309 PMID:32991956 |
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NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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G |
Mcm6 |
minichromosome maintenance complex component 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MCM6 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
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G |
Mcm7 |
minichromosome maintenance complex component 7 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MCM7 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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G |
Mcts1 |
MCTS1, re-initiation and release factor |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of MCTS1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr X:117,350,723...117,362,504
Ensembl chr X:117,350,889...117,362,504
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G |
Mdh2 |
malate dehydrogenase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MDH2 protein |
CTD |
PMID:32991956 |
|
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Me1 |
malic enzyme 1 |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of ME1 mRNA Dinitrochlorobenzene binds to ME1 protein |
CTD |
PMID:20566472 PMID:32991956 |
|
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
affects binding |
ISO |
Dinitrochlorobenzene binds to MGMT protein |
CTD |
PMID:12974631 |
|
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MGST1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
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G |
Mink1 |
misshapen-like kinase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MINK1 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:55,278,293...55,330,782
Ensembl chr10:55,278,391...55,330,782
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G |
Mki67 |
marker of proliferation Ki-67 |
affects expression affects binding |
ISO |
Dinitrochlorobenzene affects the expression of MKI67 mRNA Dinitrochlorobenzene binds to MKI67 protein |
CTD |
PMID:22302311 PMID:32991956 |
|
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MMP1 mRNA |
CTD |
PMID:20146380 |
|
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp10 |
matrix metallopeptidase 10 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of MMP10 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp12 |
matrix metallopeptidase 12 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MMP12 mRNA |
CTD |
PMID:10216232 |
|
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp3 |
matrix metallopeptidase 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MMP3 mRNA |
CTD |
PMID:20146380 |
|
NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mob1a |
MOB kinase activator 1A |
affects binding |
ISO |
Dinitrochlorobenzene binds to MOB1A protein |
CTD |
PMID:32991956 |
|
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561
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G |
Mob1b |
MOB kinase activator 1B |
affects binding |
ISO |
Dinitrochlorobenzene binds to MOB1B protein |
CTD |
PMID:32991956 |
|
NCBI chr14:19,333,058...19,365,845
Ensembl chr14:19,332,459...19,365,845
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G |
Mpo |
myeloperoxidase |
multiple interactions decreases activity decreases expression |
EXP ISO |
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein]; Sulfasalazine inhibits the reaction [Dinitrochlorobenzene results in decreased activity of MPO protein] Dinitrochlorobenzene results in decreased expression of MPO mRNA |
CTD |
PMID:17373747 PMID:17374397 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mrpl28 |
mitochondrial ribosomal protein L28 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MRPL28 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:15,148,698...15,151,581
Ensembl chr10:15,148,681...15,151,581
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G |
Mrpl35 |
mitochondrial ribosomal protein L35 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of MRPL35 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 4:103,865,812...103,876,687
Ensembl chr 4:103,865,812...103,880,887
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G |
Mrps5 |
mitochondrial ribosomal protein S5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MRPS5 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:114,821,046...114,837,291
Ensembl chr 3:114,821,046...114,837,291
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|
G |
Mrps6 |
mitochondrial ribosomal protein S6 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of MRPS6 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr11:31,295,358...31,348,483
Ensembl chr11:31,295,614...31,348,484
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|
G |
Ms4a7 |
membrane spanning 4-domains A7 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MS4A7 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260
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|
G |
Msh2 |
mutS homolog 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MSH2 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
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|
G |
Msh6 |
mutS homolog 6 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MSH6 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
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|
G |
Msn |
moesin |
affects binding |
ISO |
Dinitrochlorobenzene binds to MSN protein |
CTD |
PMID:32991956 |
|
NCBI chr X:60,996,043...61,064,011
Ensembl chr X:60,995,951...61,065,628
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G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MT2A mRNA |
CTD |
PMID:20491607 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mtap |
methylthioadenosine phosphorylase |
affects binding |
ISO |
Dinitrochlorobenzene binds to MTAP protein |
CTD |
PMID:32991956 |
|
NCBI chr 5:103,874,460...103,920,684
Ensembl chr 5:103,873,020...103,939,406
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G |
Mtbp |
MDM2 binding protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to MTBP protein |
CTD |
PMID:32991956 |
|
NCBI chr 7:86,973,215...87,055,775
Ensembl chr 7:86,973,069...87,050,827
|
|
G |
Mthfd1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MTHFD1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372
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G |
Mx2 |
MX dynamin like GTPase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of MX2 mRNA |
CTD |
PMID:19647056 |
|
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
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|
G |
Myb |
MYB proto-oncogene, transcription factor |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of MYB mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
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Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of MYC mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myh11 |
myosin heavy chain 11 |
affects binding |
ISO |
Dinitrochlorobenzene binds to MYH11 protein |
CTD |
PMID:32991956 |
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NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
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Myh9 |
myosin, heavy chain 9 |
increases metabolic processing affects binding |
ISO |
Dinitrochlorobenzene results in increased metabolism of MYH9 protein Dinitrochlorobenzene binds to MYH9 protein |
CTD |
PMID:29267982 PMID:32991956 |
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NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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Myl6b |
myosin light chain 6B |
affects binding |
ISO |
Dinitrochlorobenzene binds to MYL6B protein |
CTD |
PMID:32991956 |
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NCBI chr X:40,572,012...40,572,991
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Myo1b |
myosin Ib |
affects binding |
ISO |
Dinitrochlorobenzene binds to MYO1B protein |
CTD |
PMID:32991956 |
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NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
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Myo1d |
myosin ID |
affects binding |
ISO |
Dinitrochlorobenzene binds to MYO1D protein |
CTD |
PMID:32991956 |
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NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
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Myo1e |
myosin IE |
affects binding |
ISO |
Dinitrochlorobenzene binds to MYO1E protein |
CTD |
PMID:32991956 |
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NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
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Nae1 |
NEDD8 activating enzyme E1 subunit 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NAE1 protein |
CTD |
PMID:32991956 |
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NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371
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Nagk |
N-acetylglucosamine kinase |
affects binding |
ISO |
Dinitrochlorobenzene binds to NAGK protein |
CTD |
PMID:32991956 |
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NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137
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Nampt |
nicotinamide phosphoribosyltransferase |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of NAMPT mRNA Dinitrochlorobenzene binds to NAMPT protein |
CTD |
PMID:17374397 PMID:19371601 PMID:32991956 |
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NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Naprt |
nicotinate phosphoribosyltransferase |
affects binding |
ISO |
Dinitrochlorobenzene binds to NAPRT protein |
CTD |
PMID:32991956 |
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NCBI chr 7:107,576,645...107,580,102
Ensembl chr 7:107,576,627...107,580,102
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Ndrg3 |
NDRG family member 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NDRG3 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:145,587,505...145,650,896
Ensembl chr 3:145,548,041...145,650,873
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Ndufa2 |
NADH:ubiquinone oxidoreductase subunit A2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NDUFA2 protein |
CTD |
PMID:32991956 |
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NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
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Nefh |
neurofilament heavy chain |
affects binding |
ISO |
Dinitrochlorobenzene binds to NEFH protein |
CTD |
PMID:32991956 |
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NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions affects response to substance increases expression affects expression decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFE2L2 protein]; Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 mRNA promotes the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of DNAJB4 mRNA]; NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] Dinitrochlorobenzene affects the localization of and results in increased activity of NFE2L2 protein; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CCL3 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL10 mRNA]; NFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of IL1B mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of BCL2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of CAT mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX1 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX2 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX5 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GPX6 mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of GSR mRNA]; NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NFE2L2 mRNA] [NFE2L2 affects the susceptibility to sulforaphane] which affects the susceptibility to Dinitrochlorobenzene; NFE2L2 affects the susceptibility to Dinitrochlorobenzene Dinitrochlorobenzene affects the expression of NFE2L2 protein |
CTD |
PMID:18785192 PMID:19033392 PMID:19303893 PMID:19427879 PMID:23564646 PMID:26022718 PMID:26244607 PMID:27492222 PMID:27965148 PMID:28219650 PMID:31967339 PMID:34651546 More...
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1 |
nuclear factor kappa B subunit 1 |
decreases expression affects expression multiple interactions increases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of NFKB1 mRNA Dinitrochlorobenzene affects the expression of NFKB1 mRNA sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFKB1 mRNA] |
CTD |
PMID:20385217 PMID:28219650 PMID:34651546 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Ninj1 |
ninjurin 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of NINJ1 mRNA |
CTD |
PMID:16314067 PMID:17374397 |
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NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
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Nlrp12 |
NLR family, pyrin domain containing 12 |
decreases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in decreased expression of NLRP12 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein]; Dinitrochlorobenzene results in decreased expression of and affects the localization of NLRP12 protein |
CTD |
PMID:27585668 PMID:31276767 |
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NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934
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Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of NLRP3 protein Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] |
CTD |
PMID:31276767 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NOLC1 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
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Nop2 |
NOP2 nucleolar protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to NOP2 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
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Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression affects expression |
EXP ISO |
Curcumin inhibits the reaction [Dinitrochlorobenzene results in decreased expression of NOS2 protein] Dinitrochlorobenzene results in increased expression of NOS2 protein NFE2L2 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of NOS2 mRNA] Dinitrochlorobenzene affects the expression of NOS2 mRNA |
CTD |
PMID:17373747 PMID:28219650 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npr3 |
natriuretic peptide receptor 3 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of NPR3 mRNA |
CTD |
PMID:19527780 |
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NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
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Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases expression |
ISO |
Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NQO1 mRNA] |
CTD |
PMID:16314067 PMID:19033392 PMID:20146380 PMID:20491607 PMID:20566472 PMID:28219650 More...
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of NR0B1 mRNA |
CTD |
PMID:20146380 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of NR3C1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nrdc |
nardilysin convertase |
affects binding |
ISO |
Dinitrochlorobenzene binds to NRDC protein |
CTD |
PMID:32991956 |
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NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595
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Nrep |
neuronal regeneration related protein |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of NREP mRNA |
CTD |
PMID:17374397 |
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NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nrf1 |
nuclear respiratory factor 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of NRF1 mRNA |
CTD |
PMID:28219650 |
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NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
affects binding |
ISO |
Dinitrochlorobenzene binds to NSDHL protein |
CTD |
PMID:32991956 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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Nt5dc1 |
5'-nucleotidase domain containing 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NT5DC1 protein |
CTD |
PMID:32991956 |
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NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591
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Numa1 |
nuclear mitotic apparatus protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NUMA1 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855
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Nup155 |
nucleoporin 155 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NUP155 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148
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Nup205 |
nucleoporin 205 |
affects binding |
ISO |
Dinitrochlorobenzene binds to NUP205 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844
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Nup43 |
nucleoporin 43 |
increases methylation |
ISO |
Dinitrochlorobenzene results in increased methylation of NUP43 promoter |
CTD |
PMID:24675093 |
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NCBI chr 1:2,144,427...2,157,887
Ensembl chr 1:2,148,043...2,158,186
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G |
Nup88 |
nucleoporin 88 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of NUP88 mRNA |
CTD |
PMID:17374397 |
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NCBI chr10:55,667,903...55,692,249
Ensembl chr10:55,667,906...55,692,257
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Odc1 |
ornithine decarboxylase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ODC1 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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G |
Ola1 |
Obg-like ATPase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to OLA1 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480
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Orc1 |
origin recognition complex, subunit 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ORC1 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
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Orc5 |
origin recognition complex, subunit 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to ORC5 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:12,548,007...12,612,611
Ensembl chr 4:12,548,007...12,612,568
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Orc6 |
origin recognition complex, subunit 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of ORC6 mRNA |
CTD |
PMID:21404309 |
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NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662
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Osm |
oncostatin M |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of OSM mRNA |
CTD |
PMID:19647056 |
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NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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G |
Otud1 |
OTU deubiquitinase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of OTUD1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
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G |
Oxsr1 |
oxidative stress responsive kinase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to OXSR1 protein |
CTD |
PMID:32991956 |
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NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
affects binding |
ISO |
Dinitrochlorobenzene binds to P4HB protein |
CTD |
PMID:32991956 |
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NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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Padi4 |
peptidyl arginine deiminase 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PADI4 protein |
CTD |
PMID:32991956 |
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NCBI chr 5:153,041,351...153,074,412
Ensembl chr 5:153,041,352...153,074,362
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Paics |
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of PAICS mRNA |
CTD |
PMID:17374397 |
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NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
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G |
Papss1 |
3'-phosphoadenosine 5'-phosphosulfate synthase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PAPSS1 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PARP1 protein |
CTD |
PMID:32991956 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pcna |
proliferating cell nuclear antigen |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PCNA mRNA |
CTD |
PMID:21404309 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PCSK9 protein |
CTD |
PMID:32991956 |
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NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
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Pde4b |
phosphodiesterase 4B |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PDE4B mRNA |
CTD |
PMID:17374397 |
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NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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Pde4d |
phosphodiesterase 4D |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PDE4D mRNA |
CTD |
PMID:17374397 |
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NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
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Pdhb |
pyruvate dehydrogenase E1 subunit beta |
affects binding |
ISO |
Dinitrochlorobenzene binds to PDHB protein |
CTD |
PMID:32991956 |
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NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PDIA4 protein |
CTD |
PMID:32991956 |
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NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pds5b |
PDS5 cohesin associated factor B |
affects binding |
ISO |
Dinitrochlorobenzene binds to PDS5B protein |
CTD |
PMID:32991956 |
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NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596
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G |
Pf4 |
platelet factor 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PF4 mRNA |
CTD |
PMID:19647056 |
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NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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G |
Pfkl |
phosphofructokinase, liver type |
affects binding |
ISO |
Dinitrochlorobenzene binds to PFKL protein |
CTD |
PMID:32991956 |
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NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
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G |
Pgd |
phosphogluconate dehydrogenase |
increases expression affects binding |
ISO |
Dinitrochlorobenzene results in increased expression of PGD mRNA Dinitrochlorobenzene binds to PGD protein |
CTD |
PMID:20566472 PMID:32991956 |
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NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
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G |
Phf11 |
PHD finger protein 11 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PHF11 mRNA |
CTD |
PMID:19647056 |
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NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009
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G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PHLDA1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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G |
Picalm |
phosphatidylinositol binding clathrin assembly protein |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PICALM mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557
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G |
Pir |
pirin |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PIR mRNA |
CTD |
PMID:16314067 |
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NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
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G |
Pkm |
pyruvate kinase M1/2 |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of PKM protein |
CTD |
PMID:29267982 |
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NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PLAT mRNA |
CTD |
PMID:17374397 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plekhm3 |
pleckstrin homology domain containing M3 |
increases methylation |
ISO |
Dinitrochlorobenzene results in increased methylation of PLEKHM3 promoter |
CTD |
PMID:24675093 |
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NCBI chr 9:66,166,233...66,325,332
Ensembl chr 9:66,166,321...66,325,294
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G |
Plin2 |
perilipin 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PLIN2 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plk1 |
polo-like kinase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PLK1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
|
|
G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PMAIP1 mRNA |
CTD |
PMID:20713136 |
|
NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
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G |
Pola1 |
DNA polymerase alpha 1, catalytic subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of POLA1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
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G |
Pold3 |
DNA polymerase delta 3, accessory subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of POLD3 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665
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G |
Pole |
DNA polymerase epsilon, catalytic subunit |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of POLE mRNA |
CTD |
PMID:21404309 |
|
NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
|
|
G |
Polr2a |
RNA polymerase II subunit A |
affects binding |
ISO |
Dinitrochlorobenzene binds to POLR2A protein |
CTD |
PMID:32991956 |
|
NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
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G |
Ppa1 |
inorganic pyrophosphatase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PPA1 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215
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G |
Ppbp |
pro-platelet basic protein |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PPBP mRNA |
CTD |
PMID:19647056 |
|
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
|
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G |
Ppif |
peptidylprolyl isomerase F |
increases oxidation |
ISO |
Dinitrochlorobenzene results in increased oxidation of PPIF protein |
CTD |
PMID:26975474 |
|
NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
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|
G |
Ppl |
periplakin |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPL protein |
CTD |
PMID:32991956 |
|
NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
|
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G |
Ppp1ca |
protein phosphatase 1 catalytic subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPP1CA protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
|
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G |
Ppp2r1b |
protein phosphatase 2 scaffold subunit A beta |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPP2R1B protein |
CTD |
PMID:32991956 |
|
NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
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G |
Ppp2r5c |
protein phosphatase 2, regulatory subunit B', gamma |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPP2R5C protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPP3CA protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Ppt1 |
palmitoyl-protein thioesterase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPT1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048
|
|
G |
Ppwd1 |
peptidylprolyl isomerase domain and WD repeat containing 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PPWD1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 2:35,337,301...35,360,661
Ensembl chr 2:35,335,962...35,360,460
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G |
Prdm1 |
PR/SET domain 1 |
multiple interactions increases expression |
ISO |
BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 mRNA]; BAY 11-7085 inhibits the reaction [Dinitrochlorobenzene results in increased expression of PRDM1 protein]; PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] Dinitrochlorobenzene results in increased expression of PRDM1 mRNA; Dinitrochlorobenzene results in increased expression of PRDM1 protein |
CTD |
PMID:27585668 PMID:31276767 |
|
NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
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G |
Prdx1 |
peroxiredoxin 1 |
affects oxidation affects binding |
ISO |
Dinitrochlorobenzene affects the oxidation of PRDX1 protein Dinitrochlorobenzene binds to PRDX1 protein |
CTD |
PMID:18789312 PMID:32991956 |
|
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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G |
Prdx2 |
peroxiredoxin 2 |
increases oxidation |
ISO |
Dinitrochlorobenzene results in increased oxidation of PRDX2 protein |
CTD |
PMID:18789312 |
|
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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G |
Prdx3 |
peroxiredoxin 3 |
decreases expression increases oxidation |
ISO |
Dinitrochlorobenzene results in decreased expression of PRDX3 mRNA Dinitrochlorobenzene results in increased oxidation of PRDX3 protein |
CTD |
PMID:17374397 PMID:18789312 PMID:26975474 |
|
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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G |
Prim1 |
DNA primase subunit 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PRIM1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
|
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G |
Prkar1a |
protein kinase cAMP-dependent type I regulatory subunit alpha |
affects binding |
ISO |
Dinitrochlorobenzene binds to PRKAR1A protein |
CTD |
PMID:32991956 |
|
NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
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G |
Prkcb |
protein kinase C, beta |
affects localization |
ISO |
Dinitrochlorobenzene affects the localization of PRKCB protein |
CTD |
PMID:24136171 |
|
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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G |
Prkdc |
protein kinase, DNA-activated, catalytic subunit |
affects binding |
ISO |
Dinitrochlorobenzene binds to PRKDC protein |
CTD |
PMID:32991956 |
|
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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G |
Prpf6 |
pre-mRNA processing factor 6 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PRPF6 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991
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G |
Psap |
prosaposin |
affects binding |
ISO |
Dinitrochlorobenzene binds to PSAP protein |
CTD |
PMID:32991956 |
|
NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
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G |
Psma5 |
proteasome 20S subunit alpha 5 |
decreases expression affects binding |
ISO |
Dinitrochlorobenzene results in decreased expression of PSMA5 mRNA Dinitrochlorobenzene binds to PSMA5 protein |
CTD |
PMID:17374397 PMID:32991956 |
|
NCBI chr 2:195,896,369...195,919,733
Ensembl chr 2:195,896,365...195,919,731
|
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G |
Psmc5 |
proteasome 26S subunit, ATPase 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PSMC5 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
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G |
Psmd11 |
proteasome 26S subunit, non-ATPase 11 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PSMD11 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
|
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G |
Psmd5 |
proteasome 26S subunit, non-ATPase 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PSMD5 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
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G |
Psmd6 |
proteasome 26S subunit, non-ATPase 6 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PSMD6 protein |
CTD |
PMID:32991956 |
|
NCBI chr15:11,102,174...11,112,180
Ensembl chr15:11,102,180...11,205,620
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G |
Psme4 |
proteasome activator subunit 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PSME4 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408
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G |
Ptcra |
pre T-cell antigen receptor alpha |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of PTCRA mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235
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G |
Ptger3 |
prostaglandin E receptor 3 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of PTGER3 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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G |
Ptgr1 |
prostaglandin reductase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PTGR1 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PTGS2 mRNA |
CTD |
PMID:19371601 PMID:20146380 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to PTPN1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of PTTG1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
ISO |
Dinitrochlorobenzene promotes the reaction [[NLRP12 protein binds to NLRP3 protein binds to CASP1 protein] which binds to PYCARD protein] |
CTD |
PMID:31276767 |
|
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Pygl |
glycogen phosphorylase L |
affects binding |
ISO |
Dinitrochlorobenzene binds to PYGL protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
|
|
G |
Rab30 |
RAB30, member RAS oncogene family |
affects binding |
ISO |
Dinitrochlorobenzene binds to RAB30 protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
|
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G |
Rab32 |
RAB32, member RAS oncogene family |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of RAB32 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
|
|
G |
Rad50 |
RAD50 double strand break repair protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to RAD50 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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G |
Rars1 |
arginyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RARS1 protein |
CTD |
PMID:32991956 |
|
NCBI chr10:20,270,744...20,295,192
Ensembl chr10:20,270,483...20,295,196
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G |
Rasgrp1 |
RAS guanyl releasing protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RASGRP1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
|
|
G |
Rasl10a |
RAS-like, family 10, member A |
affects binding |
ISO |
Dinitrochlorobenzene binds to RASL10A protein |
CTD |
PMID:32991956 |
|
NCBI chr14:79,955,093...79,956,471
Ensembl chr14:79,954,398...79,956,468
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|
G |
Rbm17 |
RNA binding motif protein 17 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of RBM17 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014
|
|
G |
Rbm25 |
RNA binding motif protein 25 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RBM25 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854
|
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G |
Rbm26 |
RNA binding motif protein 26 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RBM26 protein |
CTD |
PMID:32991956 |
|
NCBI chr15:81,884,783...81,964,245
Ensembl chr15:81,887,219...81,964,118
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|
G |
Rbpj |
recombination signal binding protein for immunoglobulin kappa J region |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of RBPJ mRNA |
CTD |
PMID:17374397 |
|
NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353
|
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G |
Rcc1 |
regulator of chromosome condensation 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RCC1 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
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|
G |
Rdx |
radixin |
affects binding |
ISO |
Dinitrochlorobenzene binds to RDX protein |
CTD |
PMID:32991956 |
|
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
|
|
G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RECQL4 mRNA |
CTD |
PMID:18242016 |
|
NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation |
ISO |
aristolochic acid I inhibits the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein]; TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein] |
CTD |
PMID:31226360 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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|
G |
Rfc3 |
replication factor C subunit 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RFC3 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
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|
G |
Rfc4 |
replication factor C subunit 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RFC4 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
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|
G |
Rfc5 |
replication factor C subunit 5 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RFC5 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
|
|
G |
Rgs1 |
regulator of G-protein signaling 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RGS1 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
|
|
G |
Rgs2 |
regulator of G-protein signaling 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RGS2 mRNA |
CTD |
PMID:20146380 |
|
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
|
|
G |
Rgs21 |
regulator of G-protein signaling 21 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RGS21 protein |
CTD |
PMID:32991956 |
|
NCBI chr13:56,239,448...56,289,290
Ensembl chr13:56,240,735...56,266,573
|
|
G |
Rhoc |
ras homolog family member C |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RHOC mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
|
|
G |
Rnase2 |
ribonuclease A family member 2 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of RNASE2A mRNA |
CTD |
PMID:18242016 |
|
NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479
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|
G |
Rpl27a |
ribosomal protein L27A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RPL27A mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:163,539,732...163,542,771
|
|
G |
Rpl36 |
ribosomal protein L36 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RPL36 protein |
CTD |
PMID:32991956 |
|
NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
|
|
G |
Rpl9 |
ribosomal protein L9 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RPL9 protein |
CTD |
PMID:32991956 |
|
NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136 Ensembl chr 3:42,893,942...42,897,136
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|
G |
Rps6ka1 |
ribosomal protein S6 kinase A1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RPS6KA1 protein |
CTD |
PMID:32991956 |
|
NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
|
|
G |
Rps6ka3 |
ribosomal protein S6 kinase A3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RPS6KA3 protein |
CTD |
PMID:32991956 |
|
NCBI chr X:35,517,306...35,623,296
Ensembl chr X:35,517,306...35,623,207
|
|
G |
Rps6ka5 |
ribosomal protein S6 kinase A5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RPS6KA5 protein |
CTD |
PMID:32991956 |
|
NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
|
|
G |
Rrm1 |
ribonucleotide reductase catalytic subunit M1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RRM1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
|
|
G |
Rrm2 |
ribonucleotide reductase regulatory subunit M2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RRM2 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
|
|
G |
Rtn4ip1 |
reticulon 4 interacting protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to RTN4IP1 protein |
CTD |
PMID:32991956 |
|
NCBI chr20:47,382,251...47,422,747
Ensembl chr20:47,382,234...47,422,338
|
|
G |
Rtp4 |
receptor (chemosensory) transporter protein 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of RTP4 mRNA |
CTD |
PMID:18242016 PMID:19647056 |
|
NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437
|
|
G |
Runx3 |
RUNX family transcription factor 3 |
increases expression |
EXP |
Dinitrochlorobenzene results in increased expression of RUNX3 mRNA |
CTD |
PMID:21893156 |
|
NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
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G |
S100a10 |
S100 calcium binding protein A10 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of S100A10 mRNA |
CTD |
PMID:16314067 |
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NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
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G |
S100b |
S100 calcium binding protein B |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of S100B mRNA |
CTD |
PMID:17374397 |
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NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
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G |
Safb |
scaffold attachment factor B |
affects binding |
ISO |
Dinitrochlorobenzene binds to SAFB protein |
CTD |
PMID:32991956 |
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NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SAT1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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G |
Scyl1 |
SCY1 like pseudokinase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SCYL1 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:203,045,776...203,059,550
Ensembl chr 1:203,045,741...203,059,533
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Sdc2 |
syndecan 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SDC2 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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G |
Sdha |
succinate dehydrogenase complex flavoprotein subunit A |
affects binding |
ISO |
Dinitrochlorobenzene binds to SDHA protein |
CTD |
PMID:32991956 |
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NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
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G |
Sema4c |
semaphorin 4C |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SEMA4C mRNA |
CTD |
PMID:16314067 |
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NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128
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G |
Serbp1 |
Serpine1 mRNA binding protein 1 |
decreases expression affects binding |
ISO |
Dinitrochlorobenzene results in decreased expression of SERBP1 mRNA Dinitrochlorobenzene binds to SERBP1 protein |
CTD |
PMID:17374397 PMID:32991956 |
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NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
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G |
Serpinb13 |
serpin family B member 13 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SERPINB13 protein |
CTD |
PMID:32991956 |
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NCBI chr13:23,118,582...23,150,352
Ensembl chr13:23,118,584...23,150,760
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G |
Serpine1 |
serpin family E member 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of SERPINE1 mRNA |
CTD |
PMID:33774146 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sf3b1 |
splicing factor 3b, subunit 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SF3B1 protein |
CTD |
PMID:32991956 |
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NCBI chr 9:56,492,403...56,532,300
Ensembl chr 9:56,492,403...56,532,300
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G |
Sf3b3 |
splicing factor 3b, subunit 3 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SF3B3 protein |
CTD |
PMID:32991956 |
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NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245
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G |
Sh2b2 |
SH2B adaptor protein 2 |
decreases methylation |
ISO |
Dinitrochlorobenzene results in decreased methylation of SH2B2 promoter |
CTD |
PMID:24675093 |
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NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
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G |
Si |
sucrase-isomaltase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SI mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260
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G |
Skil |
SKI-like proto-oncogene |
affects binding |
ISO |
Dinitrochlorobenzene binds to SKIL protein |
CTD |
PMID:32991956 |
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NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
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G |
Skp2 |
S-phase kinase associated protein 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SKP2 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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G |
Slamf1 |
signaling lymphocytic activation molecule family member 1 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of SLAMF1 mRNA |
CTD |
PMID:20713136 |
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NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
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G |
Slamf8 |
SLAM family member 8 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of SLAMF8 mRNA |
CTD |
PMID:17374397 |
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NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
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G |
Slc12a9 |
solute carrier family 12, member 9 |
decreases methylation |
ISO |
Dinitrochlorobenzene results in decreased methylation of SLC12A9 promoter |
CTD |
PMID:24675093 |
|
NCBI chr12:19,368,990...19,385,881
Ensembl chr12:19,369,004...19,385,877
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G |
Slc16a10 |
solute carrier family 16 member 10 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SLC16A10 mRNA |
CTD |
PMID:17374397 |
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NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
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G |
Slc25a5 |
solute carrier family 25 member 5 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SLC25A5 protein |
CTD |
PMID:32991956 |
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NCBI chr X:116,031,896...116,034,963
Ensembl chr X:116,031,803...116,034,967
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G |
Slc2a3 |
solute carrier family 2 member 3 |
decreases expression increases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of SLC2A3 mRNA Dinitrochlorobenzene results in increased expression of SLC2A3 mRNA |
CTD |
PMID:17374397 PMID:19371601 |
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NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SLC7A5 mRNA |
CTD |
PMID:17374397 |
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NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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G |
Slfn2 |
schlafen family member 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SLFN12L protein |
CTD |
PMID:32991956 |
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NCBI chr10:67,953,322...67,959,659
Ensembl chr10:67,953,171...67,959,458
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G |
Slpi |
secretory leukocyte peptidase inhibitor |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of SLPI mRNA |
CTD |
PMID:22302311 |
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NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
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G |
Smc1a |
structural maintenance of chromosomes 1A |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of SMC1A mRNA |
CTD |
PMID:17374397 |
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NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056
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G |
Snai1 |
snail family transcriptional repressor 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SNAI1 mRNA |
CTD |
PMID:20146380 |
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NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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G |
Snu13 |
small nuclear ribonucleoprotein 13 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SNU13 protein |
CTD |
PMID:32991956 |
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NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872 Ensembl chr 1:113,565,295...113,570,872
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G |
Snx15 |
sorting nexin 15 |
increases methylation |
ISO |
Dinitrochlorobenzene results in increased methylation of SNX15 promoter |
CTD |
PMID:24675093 |
|
NCBI chr 1:203,417,029...203,426,173
Ensembl chr 1:203,417,029...203,426,247
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G |
Snx2 |
sorting nexin 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SNX2 protein |
CTD |
PMID:32991956 |
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NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865
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G |
Snx9 |
sorting nexin 9 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SNX9 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
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G |
Sod1 |
superoxide dismutase 1 |
increases expression decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SOD1 mRNA Dinitrochlorobenzene results in decreased expression of SOD1 mRNA |
CTD |
PMID:20566472 PMID:28219650 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions decreases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SOD2 mRNA Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein] Dinitrochlorobenzene results in decreased expression of SOD2 mRNA |
CTD |
PMID:7476933 PMID:16314067 PMID:20566472 PMID:28219650 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sod3 |
superoxide dismutase 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SOD3 mRNA |
CTD |
PMID:20566472 |
|
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
EXP |
Dinitrochlorobenzene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [8-bromocyclic GMP inhibits the reaction [Glucose results in increased secretion of SPP1 protein]]; Dinitrochlorobenzene inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in increased secretion of SPP1 protein]] |
CTD |
PMID:20453393 |
|
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Spta1 |
spectrin, alpha, erythrocytic 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SPTA1 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr13:86,203,504...86,279,371
Ensembl chr13:86,203,504...86,279,371
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G |
Sqle |
squalene epoxidase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SQLE mRNA |
CTD |
PMID:18242016 |
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NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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G |
Srm |
spermidine synthase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SRM mRNA |
CTD |
PMID:21404309 |
|
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
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G |
Srp72 |
signal recognition particle 72 |
decreases expression affects binding |
ISO |
Dinitrochlorobenzene results in decreased expression of SRP72 mRNA Dinitrochlorobenzene binds to SRP72 protein |
CTD |
PMID:17374397 PMID:32991956 |
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NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729
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G |
Srrm1 |
serine and arginine repetitive matrix 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SRRM1 protein |
CTD |
PMID:32991956 |
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NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
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G |
Srsf9 |
serine and arginine rich splicing factor 9 |
affects binding |
ISO |
Dinitrochlorobenzene binds to SRSF9 protein |
CTD |
PMID:32991956 |
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NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499
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G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of SRXN1 mRNA |
CTD |
PMID:20566472 PMID:25236440 |
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NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
Stat1 |
signal transducer and activator of transcription 1 |
decreases expression affects binding |
ISO |
Dinitrochlorobenzene results in decreased expression of STAT1 mRNA Dinitrochlorobenzene binds to STAT1 protein |
CTD |
PMID:17374397 PMID:32991956 |
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NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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G |
Stat4 |
signal transducer and activator of transcription 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of STAT4 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
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G |
Stat5b |
signal transducer and activator of transcription 5B |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of STAT5B mRNA |
CTD |
PMID:17374397 |
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NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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G |
Stau1 |
staufen double-stranded RNA binding protein 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to STAU1 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:155,680,000...155,725,969
Ensembl chr 3:155,680,000...155,725,909
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G |
Stip1 |
stress-induced phosphoprotein 1 |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of STIP1 protein |
CTD |
PMID:29267982 |
|
NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476
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G |
Stx11 |
syntaxin 11 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of STX11 mRNA |
CTD |
PMID:17374397 |
|
NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
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G |
Supt16h |
SPT16 homolog, facilitates chromatin remodeling subunit |
affects binding |
ISO |
Dinitrochlorobenzene binds to SUPT16H protein |
CTD |
PMID:32991956 |
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NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846
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G |
Tars1 |
threonyl-tRNA synthetase 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TARS1 protein |
CTD |
PMID:32991956 |
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NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717
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G |
Tbc1d4 |
TBC1 domain family, member 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TBC1D4 protein |
CTD |
PMID:32991956 |
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NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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G |
Tex15 |
testis expressed 15, meiosis and synapsis associated |
affects binding |
ISO |
Dinitrochlorobenzene binds to TEX15 protein |
CTD |
PMID:32991956 |
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NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467
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G |
Tfdp1 |
transcription factor Dp-1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TFDP1 mRNA |
CTD |
PMID:18242016 PMID:21404309 |
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NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
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G |
Tfec |
transcription factor EC |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TFEC mRNA |
CTD |
PMID:19647056 |
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NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
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G |
Tgif1 |
TGFB-induced factor homeobox 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TGIF1 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
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G |
Thbs1 |
thrombospondin 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of THBS1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs4 |
thrombospondin 4 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of THBS4 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Timd2 |
T-cell immunoglobulin and mucin domain containing 2 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of TIMD2 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr10:31,060,308...31,101,262
Ensembl chr10:31,060,326...31,094,623
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G |
Timm10b |
translocase of inner mitochondrial membrane 10B |
affects binding |
ISO |
Dinitrochlorobenzene binds to TIMM10B protein |
CTD |
PMID:32991956 |
|
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of TIMP1 mRNA |
CTD |
PMID:22302311 |
|
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TIMP3 mRNA |
CTD |
PMID:16314067 |
|
NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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G |
Tk1 |
thymidine kinase 1 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TK1 mRNA |
CTD |
PMID:21404309 |
|
NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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G |
Tkt |
transketolase |
increases metabolic processing |
ISO |
Dinitrochlorobenzene results in increased metabolism of TKT protein |
CTD |
PMID:29267982 |
|
NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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G |
Tlr4 |
toll-like receptor 4 |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of TLR4 mRNA; Dinitrochlorobenzene results in increased expression of TLR4 protein TLR4 protein promotes the reaction [Dinitrochlorobenzene results in increased phosphorylation of RELA protein] |
CTD |
PMID:31226360 |
|
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tmpo |
thymopoietin |
affects binding |
ISO |
Dinitrochlorobenzene binds to TMPO protein |
CTD |
PMID:32991956 |
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NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression affects expression increases secretion |
ISO |
[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; [Dacarbazine co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA; Biological Products inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; Dinitrochlorobenzene inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Lipopolysaccharides promotes the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of TNF protein] Dinitrochlorobenzene results in increased expression of TNF mRNA; Dinitrochlorobenzene results in increased expression of TNF protein [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Dinitrochlorobenzene inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; TNF protein affects the reaction [Dinitrochlorobenzene results in increased expression of CCR7 mRNA] Dinitrochlorobenzene affects the expression of TNF mRNA Dinitrochlorobenzene results in increased secretion of TNF protein |
CTD |
PMID:7476933 PMID:12202904 PMID:15304089 PMID:16675337 PMID:16687389 PMID:17118622 PMID:18495191 PMID:19647056 PMID:20385217 PMID:20417223 PMID:21782934 PMID:22245253 PMID:23200891 PMID:23454147 PMID:23499868 PMID:24964617 PMID:28826779 PMID:34651546 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip3 |
TNF alpha induced protein 3 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TNFAIP3 mRNA |
CTD |
PMID:20146380 |
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NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfaip6 |
TNF alpha induced protein 6 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TNFAIP6 mRNA |
CTD |
PMID:17374397 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf12a |
TNF receptor superfamily member 12A |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:19647056 |
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NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
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Tnfrsf4 |
TNF receptor superfamily member 4 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TNFRSF4 mRNA |
CTD |
PMID:21404309 |
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NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
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Tnfsf13 |
TNF superfamily member 13 |
decreases expression |
ISO |
Dinitrochlorobenzene results in decreased expression of TNFSF13 mRNA |
CTD |
PMID:21404309 |
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NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
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Tnfsf14 |
TNF superfamily member 14 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TNFSF14 mRNA |
CTD |
PMID:19647056 |
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NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216
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Tomm40 |
translocase of outer mitochondrial membrane 40 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TOMM40 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915
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Top2b |
DNA topoisomerase II beta |
affects binding |
ISO |
Dinitrochlorobenzene binds to TOP2B protein |
CTD |
PMID:32991956 |
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NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085
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Tpp2 |
tripeptidyl peptidase 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TPP2 protein |
CTD |
PMID:32991956 |
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NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
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Tpr |
translocated promoter region, nuclear basket protein |
affects binding |
ISO |
Dinitrochlorobenzene binds to TPR protein |
CTD |
PMID:32991956 |
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NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
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Trem1 |
triggering receptor expressed on myeloid cells 1 |
increases expression affects expression |
ISO |
Dinitrochlorobenzene results in increased expression of TREM1 protein Dinitrochlorobenzene affects the expression of TREM1 mRNA |
CTD |
PMID:33774146 |
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NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
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Trex1 |
three prime repair exonuclease 1 |
increases expression |
EXP |
Dinitrochlorobenzene results in increased expression of TREX1 mRNA |
CTD |
PMID:21893156 |
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NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
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Trim28 |
tripartite motif-containing 28 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TRIM28 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
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Trmt6 |
tRNA methyltransferase 6 non-catalytic subunit |
affects binding |
ISO |
Dinitrochlorobenzene binds to TRMT6 protein |
CTD |
PMID:32991956 |
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NCBI chr 3:120,074,899...120,086,639
Ensembl chr 3:120,074,911...120,086,559
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Trpm4 |
transient receptor potential cation channel, subfamily M, member 4 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TRPM4 protein |
CTD |
PMID:32991956 |
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NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
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Trpm6 |
transient receptor potential cation channel, subfamily M, member 6 |
affects expression |
ISO |
Dinitrochlorobenzene affects the expression of TRPM6 mRNA |
CTD |
PMID:22302311 |
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NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
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Tslp |
thymic stromal lymphopoietin |
increases expression multiple interactions |
ISO |
Dinitrochlorobenzene results in increased expression of TSLP mRNA [Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA; oleanolic acid 3-acetate inhibits the reaction [[Antigens, Dermatophagoides co-treated with Dinitrochlorobenzene] results in increased expression of TSLP mRNA] |
CTD |
PMID:19647056 PMID:23499868 |
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NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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Ttc1 |
tetratricopeptide repeat domain 1 |
affects binding |
ISO |
Dinitrochlorobenzene binds to TTC1 protein |
CTD |
PMID:32991956 |
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NCBI chr10:28,202,325...28,227,464
Ensembl chr10:28,202,325...28,227,472
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Txn1 |
thioredoxin 1 |
multiple interactions increases expression increases oxidation |
ISO |
Dinitrochlorobenzene inhibits the reaction [Selegiline results in increased expression of TXN]; Dinitrochlorobenzene inhibits the reaction [TXN protein affects the susceptibility to Selegiline] Dinitrochlorobenzene results in increased expression of TXN1 mRNA Dinitrochlorobenzene results in increased oxidation of TXN protein |
CTD |
PMID:16099847 PMID:19647056 PMID:26975474 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txn2 |
thioredoxin 2 |
increases expression increases oxidation |
ISO |
Dinitrochlorobenzene results in increased expression of TXN2 mRNA Dinitrochlorobenzene results in increased oxidation of TXN2 protein |
CTD |
PMID:20566472 PMID:26975474 |
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NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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Txnrd1 |
thioredoxin reductase 1 |
multiple interactions increases expression increases oxidation |
ISO EXP |
Dinitrochlorobenzene inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid] Dinitrochlorobenzene results in increased expression of TXNRD1 mRNA Dinitrochlorobenzene results in increased oxidation of TXNRD1 protein [Dinitrochlorobenzene binds to TXNRD1 protein] inhibits the reaction [TXNRD1 protein results in increased reduction of Dithionitrobenzoic Acid]; Dinitrochlorobenzene promotes the reaction [[TXNRD1 protein co-treated with NADP] results in increased abundance of Superoxides] |
CTD |
PMID:17229725 PMID:17374397 PMID:20146380 PMID:20457604 PMID:20566472 PMID:21782934 More...
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Txnrd2 |
thioredoxin reductase 2 |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TXNRD2 mRNA |
CTD |
PMID:20566472 |
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NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
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Tyms |
thymidylate synthetase |
increases expression |
ISO |
Dinitrochlorobenzene results in increased expression of TYMS mRNA |
CTD |
PMID:21404309 |
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NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
decreases methylation |
ISO |
Dinitrochlorobenzene results in decreased methylation of TYROBP gene |
CTD |
PMID:26732893 |
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NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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Ubac2 |
UBA domain containing 2 |
affects binding |
ISO |
Dinitrochlorobenzene binds to UBAC2 protein |
CTD |
PMID:32991956 |
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NCBI chr15:98,960,139...99,107,795
Ensembl chr15:98,960,139...99,107,787
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Ubd |
ubiquitin D |
increases expression |
EXP |
Dinitrochlorobenzene results in increased expression of UBD mRNA |
CTD |
PMID:21893156 |
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NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Ube2i |
ubiquitin-conjugating enzyme E2I |
affects binding |
ISO |
Dinitrochlorobenzene binds to UBE2I protein |
CTD |
PMID:32991956 |
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NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443 Ensembl chr10:69,701,618...69,702,443
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