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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dipentyl phthalate
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Accession:CHEBI:34680 term browser browse the term
Definition:A phthalate ester that is the dipentyl ester of benzene-1,2-dicarboxylic acid.
Synonyms:exact_synonym: dipentyl benzene-1,2-dicarboxylate
 related_synonym: 1,2-Benzenedicarboxylic acid dipentyl ester;   Amyl phthalate;   DPNP;   DPP;   Di-n-pentyl phthalate;   Diamyl phthalate;   Formula=C18H26O4;   InChI=1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3;   InChIKey=IPKKHRVROFYTEK-UHFFFAOYSA-N;   Phthalic acid diamyl ester;   Phthalic acid dipentyl ester;   SMILES=CCCCCOC(=O)c1ccccc1C(=O)OCCCCC;   di-n-Amyl phthalate
 xref: Beilstein:1987323;   CAS:131-18-0;   KEGG:C14300
 xref_mesh: MESH:C034171
 xref: PMID:19840837;   PMID:21177253;   PMID:23696197;   PMID:24116085;   PMID:26454885;   Reaxys:1987323


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dipentyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions
increases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of ACAA2 mRNA
di-n-pentyl phthalate results in increased expression of ACAA2 mRNA		 CTD PMID:25055962 PMID:33983380 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP di-n-pentyl phthalate results in increased expression of ACOX1 mRNA CTD PMID:33983380 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 increases expression EXP di-n-pentyl phthalate results in increased expression of ACSL1 mRNA CTD PMID:33983380 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP di-n-pentyl phthalate results in increased expression of ACSL3 mRNA CTD PMID:33983380 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression EXP di-n-pentyl phthalate results in decreased expression of AGTR1A mRNA; di-n-pentyl phthalate results in decreased expression of AGTR1A protein CTD PMID:36715143 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP di-n-pentyl phthalate results in decreased phosphorylation of AKT1 protein CTD PMID:36715143 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression EXP di-n-pentyl phthalate results in increased expression of ANGPTL4 mRNA CTD PMID:33983380 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Aqp7 aquaporin 7 increases expression EXP di-n-pentyl phthalate results in increased expression of AQP7 mRNA CTD PMID:33983380 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642 		JBrowse link
G Ar androgen receptor affects binding
multiple interactions		 ISO di-n-pentyl phthalate binds to AR protein
di-n-pentyl phthalate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; di-n-pentyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]		 CTD PMID:14751673 PMID:15840436 PMID:28571686 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP di-n-pentyl phthalate results in increased expression of ATP1A1 mRNA CTD PMID:19560483 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP di-n-pentyl phthalate results in decreased expression of BCL2 mRNA; di-n-pentyl phthalate results in decreased expression of BCL2 protein CTD PMID:33798595 PMID:36715143 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression EXP di-n-pentyl phthalate results in decreased expression of BMP6 mRNA CTD PMID:19560483 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Cat catalase decreases expression EXP di-n-pentyl phthalate results in decreased expression of CAT protein CTD PMID:36715143 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cort cortistatin decreases expression EXP di-n-pentyl phthalate results in decreased expression of CORT protein CTD PMID:36715143 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP di-n-pentyl phthalate results in increased expression of CPT1A mRNA CTD PMID:33983380 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression EXP di-n-pentyl phthalate results in increased expression of CPT1B mRNA CTD PMID:33983380 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP di-n-pentyl phthalate results in increased expression of CPT2 mRNA CTD PMID:33983380 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11A1 mRNA
di-n-pentyl phthalate results in decreased expression of CYP11A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11A1 protein
di-n-pentyl phthalate results in increased expression of CYP11A1 mRNA		 CTD PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26472102 More... NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 decreases expression
multiple interactions		 EXP di-n-pentyl phthalate results in decreased expression of CYP11B1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11B1 protein
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B1 mRNA		 CTD PMID:22112501 PMID:25055962 PMID:33983380 PMID:36715143 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression
multiple interactions		 EXP di-n-pentyl phthalate results in decreased expression of CYP11B2 mRNA; di-n-pentyl phthalate results in decreased expression of CYP11B2 protein
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP11B2 mRNA		 CTD PMID:22112501 PMID:25055962 PMID:33983380 PMID:36715143 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression		 EXP di-n-pentyl phthalate results in decreased activity of CYP17A1 protein
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of CYP17A1 mRNA
di-n-pentyl phthalate results in decreased expression of CYP17A1 mRNA; di-n-pentyl phthalate results in decreased expression of CYP17A1 protein		 CTD PMID:6829050 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 More... NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP di-n-pentyl phthalate results in increased expression of CYP19A1 mRNA CTD PMID:19560483 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression EXP di-n-pentyl phthalate results in increased expression of CYP27A1 mRNA CTD PMID:26472102 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression EXP di-n-pentyl phthalate results in decreased expression of CYP51 mRNA CTD PMID:26472102 PMID:33983380 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions
decreases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of DHCR7 mRNA
di-n-pentyl phthalate results in decreased expression of DHCR7 mRNA		 CTD PMID:22112501 PMID:25055962 PMID:33983380 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression EXP di-n-pentyl phthalate results in decreased expression of EBP mRNA CTD PMID:26472102 PMID:33983380 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP di-n-pentyl phthalate results in increased expression of EHHADH mRNA CTD PMID:33983380 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions		 ISO di-n-pentyl phthalate analog binds to ESR1 protein; di-n-pentyl phthalate binds to ESR1 protein
di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; Tamoxifen inhibits the reaction [di-n-pentyl phthalate binds to and results in increased activity of ESR1 protein]		 CTD PMID:15464722 PMID:15840436 PMID:20822795 PMID:28571686 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding		 ISO di-n-pentyl phthalate binds to and results in decreased activity of ESR2 protein; di-n-pentyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR2 protein]
di-n-pentyl phthalate analog binds to ESR2 protein		 CTD PMID:15464722 PMID:15840436 PMID:28571686 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression EXP di-n-pentyl phthalate results in increased expression of FABP1 mRNA CTD PMID:33983380 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression EXP di-n-pentyl phthalate results in increased expression of FADS2 mRNA CTD PMID:33983380 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP di-n-pentyl phthalate results in decreased expression of FGFR2 mRNA CTD PMID:26472102 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fsd2 fibronectin type III and SPRY domain containing 2 decreases expression EXP di-n-pentyl phthalate results in decreased expression of FSD2 mRNA CTD PMID:26472102 NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472 		JBrowse link
G Gata4 GATA binding protein 4 increases expression EXP di-n-pentyl phthalate results in increased expression of GATA4 mRNA CTD PMID:22112501 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression EXP di-n-pentyl phthalate results in increased expression of GNRHR mRNA CTD PMID:33798595 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of GPX1 protein CTD PMID:36715143 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grb14 growth factor receptor bound protein 14 increases expression EXP di-n-pentyl phthalate results in increased expression of GRB14 mRNA CTD PMID:15728792 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HEY1 mRNA CTD PMID:26472102 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP di-n-pentyl phthalate results in decreased expression of HMGCR mRNA CTD PMID:33983380 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HMGCS1 mRNA CTD PMID:33983380 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP di-n-pentyl phthalate results in increased expression of HMGCS2 mRNA CTD PMID:33983380 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP di-n-pentyl phthalate results in decreased expression of HNF1A mRNA CTD PMID:15728792 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO di-n-pentyl phthalate inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HSD11B2 mRNA CTD PMID:19560483 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression EXP di-n-pentyl phthalate results in increased expression of HSD17B11 mRNA CTD PMID:26472102 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HSD17B3 mRNA; di-n-pentyl phthalate results in decreased expression of HSD17B3 protein CTD PMID:33798595 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd17b8 hydroxysteroid (17-beta) dehydrogenase 8 increases expression EXP di-n-pentyl phthalate results in increased expression of HSD17B8 mRNA CTD PMID:19560483 PMID:26472102 NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HSD3B1 mRNA; di-n-pentyl phthalate results in decreased expression of HSD3B1 protein CTD PMID:33798595 PMID:36715143 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 decreases expression EXP di-n-pentyl phthalate results in decreased expression of HSD3B3 mRNA CTD PMID:33983380 NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033 		JBrowse link
G Id1 inhibitor of DNA binding 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of ID1 mRNA CTD PMID:26472102 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP di-n-pentyl phthalate results in decreased expression of IGFBP7 mRNA CTD PMID:19560483 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Inha inhibin subunit alpha multiple interactions
decreases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INHA mRNA
di-n-pentyl phthalate results in decreased expression of INHA mRNA		 CTD PMID:25055962 PMID:26472102 PMID:33983380 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of INSIG1 mRNA CTD PMID:15728792 PMID:33983380 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Insl3 insulin-like 3 multiple interactions
decreases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of INSL3 mRNA
di-n-pentyl phthalate results in decreased expression of INSL3 mRNA		 CTD PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 PMID:26454885 More... NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression EXP di-n-pentyl phthalate results in decreased expression of LDLR mRNA CTD PMID:15728792 PMID:33983380 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
decreases secretion		 EXP di-n-pentyl phthalate results in decreased expression of LHB mRNA
di-n-pentyl phthalate results in decreased secretion of LHB protein		 CTD PMID:33798595 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP di-n-pentyl phthalate results in decreased expression of LHCGR mRNA; di-n-pentyl phthalate results in decreased expression of LHCGR protein CTD PMID:15728792 PMID:33798595 PMID:33983380 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Mc2r melanocortin 2 receptor decreases expression EXP di-n-pentyl phthalate results in decreased expression of MC2R mRNA; di-n-pentyl phthalate results in decreased expression of MC2R protein CTD PMID:36715143 NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488 		JBrowse link
G Msh2 mutS homolog 2 decreases expression
increases expression		 EXP di-n-pentyl phthalate results in decreased expression of MSH2 mRNA
di-n-pentyl phthalate results in increased expression of MSH2 mRNA		 CTD PMID:26472102 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Mvd mevalonate diphosphate decarboxylase decreases expression EXP di-n-pentyl phthalate results in decreased expression of MVD mRNA CTD PMID:33983380 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971 		JBrowse link
G Myocd myocardin decreases expression EXP di-n-pentyl phthalate results in decreased expression of MYOCD mRNA CTD PMID:26472102 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression
multiple interactions		 EXP di-n-pentyl phthalate results in decreased expression of NR0B1 mRNA
[Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of NR0B1 mRNA		 CTD PMID:15728792 PMID:22112501 PMID:25055962 PMID:33983380 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO di-n-pentyl phthalate binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects binding
increases activity		 ISO di-n-pentyl phthalate analog binds to NR1I3 protein; di-n-pentyl phthalate binds to NR1I3 protein
di-n-pentyl phthalate results in increased activity of NR1I3 protein		 CTD PMID:25938866 PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression EXP di-n-pentyl phthalate results in increased expression of NR4A1 mRNA CTD PMID:15728792 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP di-n-pentyl phthalate results in decreased expression of NR4A2 protein CTD PMID:36715143 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression EXP di-n-pentyl phthalate results in decreased expression of NR4A3 mRNA CTD PMID:19560483 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of NR5A1 mRNA; di-n-pentyl phthalate results in decreased expression of NR5A1 protein CTD PMID:36715143 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression EXP di-n-pentyl phthalate results in decreased expression of NSDHL mRNA CTD PMID:19560483 PMID:33983380 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 increases expression EXP di-n-pentyl phthalate results in increased expression of PCK1 mRNA CTD PMID:33983380 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pomc proopiomelanocortin decreases expression EXP di-n-pentyl phthalate results in decreased expression of POMC protein CTD PMID:36715143 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO di-n-pentyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO di-n-pentyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
multiple interactions		 ISO di-n-pentyl phthalate binds to PPARG protein
di-n-pentyl phthalate binds to and results in increased activity of PPARG protein		 CTD PMID:23843199 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO di-n-pentyl phthalate binds to RXRA protein CTD PMID:23843199 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO di-n-pentyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO di-n-pentyl phthalate binds to RXRG protein CTD PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
decreases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SCARB1 mRNA
di-n-pentyl phthalate results in decreased expression of SCARB1 mRNA; di-n-pentyl phthalate results in decreased expression of SCARB1 protein		 CTD PMID:19560483 PMID:22112501 PMID:25055962 PMID:26472102 PMID:33798595 More... NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP di-n-pentyl phthalate results in increased expression of SCD mRNA CTD PMID:33983380 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Shox1 SHOX homeobox 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of RHOX10 mRNA CTD PMID:22112501 NCBI chr  X:116,688,163...116,695,111
Ensembl chr  X:116,688,163...116,695,058 		JBrowse link
G Sirt1 sirtuin 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of SIRT1 protein CTD PMID:33798595 PMID:36715143 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression EXP di-n-pentyl phthalate results in increased expression of SLC27A2 mRNA CTD PMID:33983380 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Snx17 sorting nexin 17 multiple interactions EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of SNX17 mRNA CTD PMID:25055962 NCBI chr 6:25,177,528...25,183,001
Ensembl chr 6:25,177,391...25,183,030 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of SOD1 protein CTD PMID:36715143 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sox9 SRY-box transcription factor 9 decreases expression EXP di-n-pentyl phthalate results in decreased expression of SOX9 mRNA CTD PMID:26472102 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP di-n-pentyl phthalate results in decreased expression of SRD5A1 mRNA CTD PMID:19560483 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
increases expression		 EXP [Simvastatin co-treated with di-n-pentyl phthalate] results in decreased expression of STAR mRNA
di-n-pentyl phthalate results in decreased expression of STAR mRNA; di-n-pentyl phthalate results in decreased expression of STAR protein
di-n-pentyl phthalate results in increased expression of STAR mRNA		 CTD PMID:19560483 PMID:21177253 PMID:21633115 PMID:22112501 PMID:25055962 More... NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tcf21 transcription factor 21 decreases expression EXP di-n-pentyl phthalate results in decreased expression of TCF21 mRNA CTD PMID:26472102 NCBI chr 1:22,701,353...22,704,212
Ensembl chr 1:22,701,353...22,704,202 		JBrowse link
G Wnt7a Wnt family member 7A decreases expression EXP di-n-pentyl phthalate results in decreased expression of WNT7A mRNA CTD PMID:33983380 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      application 19730
        plasticiser 11406
          dipentyl phthalate 90
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            heteroorganic entity 19549
                              organochalcogen compound 19309
                                organooxygen compound 19204
                                  carbon oxoacid 18689
                                    carboxylic acid 18686
                                      monocarboxylic acid 18026
                                        fatty acid 16849
                                          fatty acid derivative 8991
                                            fatty alcohol 6145
                                              short-chain fatty alcohol 92
                                                pentanol 92
                                                  pentan-1-ol 92
                                                    dipentyl phthalate 90
paths to the root