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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:boldenone
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Accession:CHEBI:34584 term browser browse the term
Definition:An 3-oxo-Δ1,Δ4-steroid substituted by an oxo group at position 3 and a β-hydroxy group at position 17. It is an anabolic androgenic steroid that has been developed for veterinary use.
Synonyms:related_synonym: (17beta)-17-hydroxyandrosta-1,4-dien-3-one;   1,2-Dehydrotestosterone;   1,2-Didehydrotestosterone;   1,4-Androstadien-17beta-ol-3-one;   17-beta-hydroxyandrosta-1,4-dien-3-one;   17beta-Boldenone;   boldenona;   boldenonum
 xref: CAS:846-48-0;   DrugBank:DB01541
 xref_mesh: MESH:C013915
 xref: Patent:US2837464;   Patent:US2875196;   Reaxys:2625467;   kegg.compound:C14502;   kegg.drug:D07536;   lipidmaps:LMST02020018;   pubmed:17084871;   pubmed:23534422;   pubmed:24097356;   pubmed:24259377;   wikipedia.en:Boldenone
 chemrof_formula: C19H26O2
 chemrof_inchi: InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
 chemrof_inchikey: RSIHSRDYCUFFLA-DYKIIFRCSA-N
 chemrof_smiles: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]


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boldenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx5 glutathione peroxidase 5 increases expression ISO boldenone results in increased expression of GPX5 mRNA CTD PMID:1301385 NCBI chr17:48,131,853...48,138,801
Ensembl chr17:48,093,895...48,138,801 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA] CTD PMID:34719837 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA] CTD PMID:34719837 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein] CTD PMID:34719837 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein] CTD PMID:34719837 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA] CTD PMID:34719837 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA] CTD PMID:34719837 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:108,418,513...108,443,328 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        molecular messenger 19151
          hormone 19098
            steroid hormone 6953
              anabolic androgenic steroid 438
                boldenone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            heteroorganic entity 20201
                              organochalcogen compound 19822
                                organooxygen compound 19713
                                  carbonyl compound 18827
                                    ketone 17484
                                      oxo steroid 9896
                                        3-oxo steroid 9875
                                          3-oxo-Delta(1) steroid 5259
                                            3-oxo-Delta(1),Delta(4)-steroid 5259
                                              boldenone 7
paths to the root