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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:boldenone
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Accession:CHEBI:34584 term browser browse the term
Definition:An 3-oxo-Delta(1),Delta(4)-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been developed for veterinary use.
Synonyms:exact_synonym: (17beta)-17-hydroxyandrosta-1,4-dien-3-one
 related_synonym: 1,2-Dehydrotestosterone;   1,2-Didehydrotestosterone;   1,4-Androstadien-17beta-ol-3-one;   17beta-Boldenone;   17beta-hydroxyandrosta-1,4-dien-3-one;   Formula=C19H26O2;   InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1;   InChIKey=RSIHSRDYCUFFLA-DYKIIFRCSA-N;   SMILES=C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2O;   boldenona;   boldenonum
 xref: CAS:846-48-0;   DrugBank:DB01541;   KEGG:C14502;   KEGG:D07536;   LIPID_MAPS_instance:LMST02020018
 xref_mesh: MESH:C013915
 xref: PMID:17084871;   PMID:23534422;   PMID:24097356;   PMID:24259377;   Patent:US2837464;   Patent:US2875196;   Reaxys:2625467;   Wikipedia:Boldenone


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boldenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpx5 glutathione peroxidase 5 increases expression ISO boldenone results in increased expression of GPX5 mRNA CTD PMID:1301385 NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of IL1B mRNA] CTD PMID:34719837 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of MYD88 mRNA] CTD PMID:34719837 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of RELA protein] CTD PMID:34719837 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TLR4 protein] CTD PMID:34719837 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TNF mRNA] CTD PMID:34719837 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions EXP [boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA; Curcumin inhibits the reaction [[boldenone undecylenate results in increased abundance of boldenone] which results in increased expression of TRAF6 mRNA] CTD PMID:34719837 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        molecular messenger 18659
          hormone 18489
            steroid hormone 7891
              anabolic androgenic steroid 437
                boldenone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbonyl compound 18908
                                    ketone 17258
                                      oxo steroid 10532
                                        3-oxo steroid 9922
                                          3-oxo-Delta(1) steroid 5223
                                            3-oxo-Delta(1),Delta(4)-steroid 5223
                                              boldenone 7
paths to the root