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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Aurin
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Accession:CHEBI:34544 term browser browse the term
Definition:A diarylmethane that has formula C19H14O3.
Synonyms:related_synonym: Formula=C19H14O3;   InChI=1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H;   InChIKey=FYEHYMARPSSOBO-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)C(c1ccc(O)cc1)=C1C=CC(=O)C=C1
 xref: CAS:603-45-2;   KEGG:C14213
 xref_mesh: MESH:C017037


show annotations for term's descendants           Sort by:
Aurin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor decreases expression ISO aurin results in decreased expression of AHR protein CTD PMID:25477506 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ar androgen receptor affects binding EXP aurin binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO aurin results in increased expression of CDKN1A mRNA CTD PMID:25477506 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cryab crystallin, alpha B increases expression ISO aurin results in increased expression of CRYAB mRNA CTD PMID:25477506 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO aurin results in decreased expression of CXCL10 mRNA CTD PMID:25477506 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO aurin results in decreased expression of CYP1A1 mRNA CTD PMID:25477506 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO aurin results in increased expression of DDIT3 mRNA; aurin results in increased expression of DDIT3 protein CTD PMID:25477506 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression ISO aurin results in increased expression of DNAJA1 mRNA CTD PMID:25477506 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO aurin results in increased expression of DNAJB4 mRNA CTD PMID:25477506 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089 		JBrowse link
G Egr1 early growth response 1 increases expression ISO aurin results in increased expression of EGR1 mRNA CTD PMID:25477506 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO aurin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25477506 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO aurin results in increased phosphorylation of EIF2S1 protein CTD PMID:25477506 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO aurin inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]; aurin inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA] CTD PMID:19255438 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO aurin results in increased expression of GADD45A mRNA CTD PMID:25477506 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO aurin results in increased expression of GDF15 mRNA CTD PMID:25477506 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO aurin results in increased expression of HMOX1 mRNA; aurin results in increased expression of HMOX1 protein CTD PMID:25477506 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsf1 heat shock transcription factor 1 affects localization ISO aurin affects the localization of HSF1 protein CTD PMID:25477506 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO aurin results in increased expression of HSPA1A mRNA; aurin results in increased expression of HSPA1A protein CTD PMID:25477506 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like increases expression ISO aurin results in increased expression of HSPA1L mRNA CTD PMID:25477506 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO aurin results in increased expression of HSPA6 mRNA CTD PMID:25477506 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression ISO aurin results in increased expression of HSPB1 mRNA CTD PMID:25477506 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO aurin results in increased expression of HSPH1 mRNA CTD PMID:25477506 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO aurin results in decreased expression of IL1B mRNA CTD PMID:25477506 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression ISO aurin results in decreased expression of IL6 mRNA CTD PMID:25477506 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases activity
multiple interactions		 ISO aurin results in decreased activity of NR3C1 protein
aurin inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA]		 CTD PMID:19255438 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
increases response to substance		 ISO aurin results in increased expression of PMAIP1 mRNA; aurin results in increased expression of PMAIP1 protein
PMAIP1 protein results in increased susceptibility to aurin		 CTD PMID:25477506 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO aurin results in increased expression of SERPINE1 mRNA CTD PMID:25477506 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO aurin binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      group 19878
        polyatomic entity 19877
          molecule 19770
            cyclic compound 19535
              organic cyclic compound 19545
                organic aromatic compound 19380
                  diarylmethane 9457
                    Aurin 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      p-block molecular entity 19866
                        carbon group molecular entity 19805
                          organic molecular entity 19775
                            organic molecule 19755
                              organic cyclic compound 19545
                                organic aromatic compound 19380
                                  diarylmethane 9457
                                    Aurin 28
paths to the root