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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-octylphenol
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Accession:CHEBI:34432 term browser browse the term
Definition:A member of the class of phenols that is phenol which is substituted at the para- position by an octyl group.
Synonyms:related_synonym: 1-(p-hydroxyphenyl)octane;   4-n-octylphenol;   Formula=C14H22O;   InChI=1S/C14H22O/c1-2-3-4-5-6-7-8-13-9-11-14(15)12-10-13/h9-12,15H,2-8H2,1H3;   InChIKey=NTDQQZYCCIDJRK-UHFFFAOYSA-N;   SMILES=CCCCCCCCc1ccc(O)cc1;   p-octylphenol
 xref: CAS:1806-26-4;   KEGG:C14132
 xref_mesh: MESH:C080417
 xref: PMID:20980040;   PMID:22435736;   PMID:23435201;   PMID:23520882;   PMID:23562958;   PMID:23714150;   PMID:23818073;   PMID:23877625;   PMID:24209326;   Reaxys:2046736


show annotations for term's descendants           Sort by:
4-octylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP 4-octylphenol binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ar androgen receptor affects binding
multiple interactions		 EXP
ISO		 4-octylphenol binds to AR protein
4-octylphenol inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]		 CTD PMID:14565775 PMID:16169144 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO 4-octylphenol results in increased expression of B4GALT1 mRNA CTD PMID:14605097 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Bad BCL2-associated agonist of cell death increases phosphorylation ISO 4-octylphenol results in increased phosphorylation of BAD protein CTD PMID:31345089 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO 4-octylphenol results in increased expression of BAK1 mRNA CTD PMID:31345089 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 4-octylphenol results in increased expression of BAX mRNA CTD PMID:31345089 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 4-octylphenol results in decreased expression of BCL2 mRNA CTD PMID:31345089 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO 4-octylphenol results in increased cleavage of CASP3 protein CTD PMID:31345089 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd86 CD86 molecule increases expression ISO 4-octylphenol results in increased expression of CD86 protein CTD PMID:37207816 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression ISO 4-octylphenol results in decreased expression of CDO1 mRNA CTD PMID:16223563 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:11711029 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:11711029 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:11711029 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO 4-octylphenol inhibits the reaction [Acetylcholine affects the activity of [CHRNA3 protein binds to CHRNB4 protein]] CTD PMID:11711029 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Cycs cytochrome c, somatic increases secretion ISO 4-octylphenol results in increased secretion of CYCS protein CTD PMID:31345089 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP 4-octylphenol results in decreased expression of CYP17A1 protein CTD PMID:9361775 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Eeig1 estrogen-induced osteoclastogenesis regulator 1 increases expression ISO 4-octylphenol results in increased expression of EEIG1 mRNA CTD PMID:14605097 NCBI chr 3:15,822,441...15,854,651
Ensembl chr 3:15,823,144...15,854,643 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
affects binding
affects localization
multiple interactions		 ISO
EXP		 4-octylphenol results in increased activity of ESR1 protein
4-octylphenol binds to ESR1 protein
4-octylphenol affects the localization of ESR1 protein
[4-octylphenol co-treated with ESR1 protein] results in increased expression of LTF mRNA		 CTD PMID:18028983 PMID:19913605 PMID:20950447 PMID:21783566 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
affects localization		 ISO [4-octylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA
4-octylphenol binds to ESR2 protein
4-octylphenol affects the localization of ESR2 protein		 CTD PMID:19913605 PMID:20950447 PMID:21783566 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4-octylphenol results in increased expression of FOS mRNA; 4-octylphenol results in increased expression of FOS protein CTD PMID:24308608 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gh1 growth hormone 1 increases expression
multiple interactions
increases secretion		 EXP 4-octylphenol results in increased expression of GH1 mRNA
fulvestrant inhibits the reaction [4-octylphenol results in increased expression of GH1 mRNA]; fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of GH1 protein]		 CTD PMID:19463694 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO 4-octylphenol affects the reaction [HRAS protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene] CTD PMID:12117780 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO 4-octylphenol results in decreased activity of HSD11B2 protein CTD PMID:16184081 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions		 ISO 4-octylphenol results in increased expression of ICAM1 protein
4-octylphenol promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]		 CTD PMID:37207816 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO 4-octylphenol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions		 ISO 4-octylphenol results in decreased expression of IL10
4-octylphenol results in decreased expression of and results in decreased secretion of IL10 protein		 CTD PMID:20056579 PMID:24039973 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO 4-octylphenol results in increased expression of IL1A protein CTD PMID:37207816 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 decreases expression ISO 4-octylphenol results in decreased expression of IL6 mRNA CTD PMID:37207816 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO 4-octylphenol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Kmt2a lysine methyltransferase 2A increases expression ISO 4-octylphenol results in increased expression of KMT2A protein CTD PMID:20056579 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Ltf lactotransferrin multiple interactions ISO [4-octylphenol co-treated with ESR1 protein] results in increased expression of LTF mRNA; [4-octylphenol co-treated with ESR2 protein] results in increased expression of LTF mRNA CTD PMID:21783566 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO
EXP		 4-octylphenol inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; 4-octylphenol inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; 4-octylphenol inhibits the reaction [Estrone results in increased phosphorylation of MAPK1 protein]
4-octylphenol results in increased phosphorylation of MAPK1 protein
4-octylphenol analog affects the reaction [Estradiol affects the phosphorylation of MAPK1 protein]; 4-octylphenol analog affects the reaction [Estriol affects the phosphorylation of MAPK1 protein]; 4-octylphenol analog affects the reaction [Estrone affects the phosphorylation of MAPK1 protein]		 CTD PMID:19463694 PMID:20870566 PMID:20950447 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 4-octylphenol inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; 4-octylphenol inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; 4-octylphenol inhibits the reaction [Estrone results in increased phosphorylation of MAPK3 protein]
4-octylphenol results in increased phosphorylation of MAPK3 protein
4-octylphenol analog affects the reaction [Estradiol affects the phosphorylation of MAPK3 protein]; 4-octylphenol analog affects the reaction [Estriol affects the phosphorylation of MAPK3 protein]; 4-octylphenol analog affects the reaction [Estrone affects the phosphorylation of MAPK3 protein]		 CTD PMID:19463694 PMID:20870566 PMID:20950447 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 4-octylphenol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects activity ISO 4-octylphenol affects the activity of NR1I2 protein CTD PMID:20024649 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases activity		 ISO 4-octylphenol binds to and results in decreased activity of NR1I3 protein alternative form
4-octylphenol results in increased activity of NR1I3 protein		 CTD PMID:20869355 PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions
decreases activity		 EXP 4-octylphenol inhibits the reaction [Triiodothyronine, Reverse binds to P4HB protein]
4-octylphenol results in decreased activity of P4HB protein		 CTD PMID:16617682 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 decreases expression ISO 4-octylphenol results in decreased expression of PAPSS1 mRNA CTD PMID:16223563 NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 decreases expression ISO 4-octylphenol results in decreased expression of PAPSS2 mRNA CTD PMID:16223563 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331 		JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO 4-octylphenol results in increased expression of PDZK1 mRNA CTD PMID:14605097 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Prl prolactin multiple interactions
increases secretion
increases expression		 ISO
EXP		 4-octylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; 4-octylphenol affects the reaction [Estrone results in increased secretion of PRL protein]; 4-octylphenol inhibits the reaction [Estradiol results in increased secretion of PRL protein]
fulvestrant inhibits the reaction [4-octylphenol results in increased expression of PRL mRNA]; fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of PRL protein]		 CTD PMID:19463694 PMID:20950447 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4-octylphenol binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Skil SKI-like proto-oncogene increases expression ISO 4-octylphenol results in increased expression of SKIL protein CTD PMID:24308608 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases metabolic processing ISO SULT1A1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases metabolic processing ISO SULT1B1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases metabolic processing ISO SULT2A1 protein results in increased metabolism of 4-octylphenol CTD PMID:10623578 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Suox sulfite oxidase decreases expression ISO 4-octylphenol results in decreased expression of SUOX mRNA CTD PMID:16223563 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 ISO 4-octylphenol results in increased expression of TNF
4-octylphenol results in increased expression of and results in increased secretion of TNF protein; anacardic acid inhibits the reaction [4-octylphenol results in increased expression of and results in increased secretion of TNF protein]		 CTD PMID:20056579 PMID:24039973 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Wdr5 WD repeat domain 5 increases expression ISO 4-octylphenol results in increased expression of WDR5 protein CTD PMID:20056579 NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671 		JBrowse link
Nonidet P-40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO Nonidet P-40 results in decreased expression of ARNT mRNA CTD PMID:26552463 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Nonidet P-40 results in increased expression of ATF4 mRNA CTD PMID:26552463 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Nonidet P-40 results in increased expression of ATF6 mRNA CTD PMID:26552463 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Nonidet P-40 results in increased expression of ATF6B mRNA CTD PMID:26552463 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Nonidet P-40 results in increased expression of ATG12 mRNA CTD PMID:26552463 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 decreases expression ISO Nonidet P-40 results in decreased expression of ATG5 mRNA CTD PMID:26552463 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 decreases expression ISO Nonidet P-40 results in decreased expression of ATG7 mRNA CTD PMID:26552463 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Nonidet P-40 results in decreased expression of ATR mRNA CTD PMID:26552463 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Nonidet P-40 results in increased expression of BBC3 mRNA CTD PMID:26552463 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Becn1 beclin 1 increases expression ISO Nonidet P-40 results in increased expression of BECN1 mRNA CTD PMID:26552463 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Nonidet P-40 results in increased expression of BID mRNA CTD PMID:26552463 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Nonidet P-40 results in increased expression of BNIP3L mRNA CTD PMID:26552463 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Calr calreticulin decreases expression ISO Nonidet P-40 results in decreased expression of CALR mRNA CTD PMID:26552463 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO Nonidet P-40 results in decreased expression of CA9 mRNA CTD PMID:26552463 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 decreases expression ISO Nonidet P-40 results in decreased expression of CASP1 mRNA CTD PMID:26552463 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Nonidet P-40 results in increased expression of CCL2 mRNA CTD PMID:26552463 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Nonidet P-40 results in increased expression of CDKN1A mRNA CTD PMID:26552463 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Nonidet P-40 results in increased expression of CHEK2 mRNA CTD PMID:26552463 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Crp C-reactive protein increases expression ISO Nonidet P-40 results in increased expression of CRP mRNA CTD PMID:26552463 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of DDB2 mRNA CTD PMID:26552463 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Nonidet P-40 results in increased expression of DDIT3 mRNA CTD PMID:26552463 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Nonidet P-40 results in increased expression of DNAJC3 mRNA CTD PMID:26552463 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Epo erythropoietin decreases expression ISO Nonidet P-40 results in decreased expression of EPO mRNA CTD PMID:26552463 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Nonidet P-40 results in increased expression of GADD45A mRNA CTD PMID:26552463 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Nonidet P-40 results in decreased expression of GCLC mRNA CTD PMID:26552463 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of GRB2 mRNA CTD PMID:26552463 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Nonidet P-40 results in increased expression of HMOX1 mRNA CTD PMID:26552463 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Nonidet P-40 results in increased expression of HSP90AA1 mRNA CTD PMID:26552463 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO Nonidet P-40 results in increased expression of HSPA4 mRNA CTD PMID:26552463 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO Nonidet P-40 results in increased expression of HSPA4L mRNA CTD PMID:26552463 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Nonidet P-40 results in decreased expression of HSPA5 mRNA CTD PMID:26552463 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Nonidet P-40 results in increased expression of HUS1 mRNA CTD PMID:26552463 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Ifng interferon gamma decreases expression ISO Nonidet P-40 results in decreased expression of IFNG mRNA CTD PMID:26552463 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Nonidet P-40 results in decreased expression of IL1A mRNA CTD PMID:26552463 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 increases expression ISO Nonidet P-40 results in increased expression of IL6 mRNA CTD PMID:26552463 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Nonidet P-40 results in decreased expression of LDHA mRNA CTD PMID:26552463 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Nonidet P-40 results in increased expression of MCL1 mRNA CTD PMID:26552463 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Nonidet P-40 results in decreased expression of MMP9 mRNA CTD PMID:26552463 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease increases expression ISO Nonidet P-40 results in increased expression of MRE11A mRNA CTD PMID:26552463 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nbn nibrin increases expression ISO Nonidet P-40 results in increased expression of NBN mRNA CTD PMID:26552463 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Nonidet P-40 results in increased expression of NQO1 mRNA CTD PMID:26552463 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nonidet P-40 results in decreased expression of PARP1 mRNA CTD PMID:26552463 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component increases expression ISO Nonidet P-40 results in increased expression of RAD17 mRNA CTD PMID:26552463 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072 		JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Nonidet P-40 results in decreased expression of RAD51 mRNA CTD PMID:26552463 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO Nonidet P-40 results in increased expression of RAD9A mRNA CTD PMID:26552463 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Nonidet P-40 results in decreased expression of SERPINE1 mRNA CTD PMID:26552463 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Nonidet P-40 results in increased expression of SLC2A1 mRNA CTD PMID:26552463 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Nonidet P-40 results in decreased expression of SQSTM1 mRNA CTD PMID:26552463 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Nonidet P-40 results in decreased expression of TLR4 mRNA CTD PMID:26552463 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF10A mRNA CTD PMID:26552463 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF1A mRNA CTD PMID:26552463 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Nonidet P-40 results in decreased expression of TP53 mRNA CTD PMID:26552463 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Nonidet P-40 results in decreased expression of TXN mRNA CTD PMID:26552463 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Nonidet P-40 results in increased expression of TXNRD1 mRNA CTD PMID:26552463 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases expression ISO Nonidet P-40 results in decreased expression of ULK1 mRNA CTD PMID:26552463 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nonidet P-40 results in decreased expression of VEGFA mRNA CTD PMID:26552463 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression ISO Nonidet P-40 results in decreased expression of XPC mRNA CTD PMID:26552463 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      chemical role 19507
        emulsifier 7547
          surfactant 7533
            4-octylphenol 105
              Nonidet P-40 58
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            organic molecule 19737
                              organic cyclic compound 19526
                                organic aromatic compound 19390
                                  phenols 18674
                                    4-octylphenol 105
                                      Nonidet P-40 58
paths to the root