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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:stilbene-4,4'-diol
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Accession:CHEBI:34368 term browser browse the term
Definition:A stilbenol that has formula C14H12O2.
Synonyms:related_synonym: 4,4'-(1,2-ethenediyl)bisphenol;   4,4'-(ethene-1,2-diyl)diphenol;   4,4'-Dihydroxystilbene;   4,4'-ethene-1,2-diyldiphenol;   p,p'-dihydroxystilbene
 xref: Beilstein:2329460;   CAS:659-22-3;   Gmelin:1652560
 xref_mesh: MESH:C010118
 xref: kegg.compound:C14233
 chemrof_formula: C14H12O2
 chemrof_inchi: InChI=1S/C14H12O2/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h1-10,15-16H
 chemrof_inchikey: XLAIWHIOIFKLEO-UHFFFAOYSA-N
 chemrof_smiles: [H]C(=C([H])c1ccc(O)cc1)c1ccc(O)cc1
 cyclic_relationship: has_parent_hybride CHEBI:26775


show annotations for term's descendants           Sort by:
stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression 		ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA 		CTD PMID:21554123 NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719 		JBrowse link
G Edn1 endothelin 1 decreases expression
decreases secretion 		ISO 4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA
4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein 		CTD PMID:21554123 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
trans-stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression 		ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA 		CTD PMID:21554123 NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719 		JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression 		ISO 4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein
4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA 		CTD PMID:21554123 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,831,716...54,849,162
Ensembl chr10:54,831,718...54,838,760 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      atom 20872
        nonmetal atom 20781
          carbon atom 20706
            organic molecular entity 20706
              olefinic compound 16427
                stilbenoid 8209
                  stilbenol 6513
                    stilbene-4,4'-diol 10
                      cis-stilbene-4,4'-diol 0
                      trans-stilbene-4,4'-diol 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                organic aromatic compound 20199
                                  stilbenoid 8209
                                    stilbenol 6513
                                      stilbene-4,4'-diol 10
                                        cis-stilbene-4,4'-diol 0
                                        trans-stilbene-4,4'-diol 10
paths to the root