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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:stilbene-4,4'-diol
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Accession:CHEBI:34368 term browser browse the term
Definition:A stilbenol that has formula C14H12O2.
Synonyms:exact_synonym: 4,4'-(ethene-1,2-diyl)diphenol
 related_synonym: 4,4'-(1,2-ethenediyl)bisphenol;   4,4'-Dihydroxystilbene;   4,4'-ethene-1,2-diyldiphenol;   Formula=C14H12O2;   InChI=1S/C14H12O2/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h1-10,15-16H;   InChIKey=XLAIWHIOIFKLEO-UHFFFAOYSA-N;   SMILES=[H]C(=C([H])c1ccc(O)cc1)c1ccc(O)cc1;   p,p'-dihydroxystilbene
 xref: Beilstein:2329460;   CAS:659-22-3;   Gmelin:1652560;   KEGG:C14233
 xref_mesh: MESH:C010118


show annotations for term's descendants           Sort by:
stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression		 ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA		 CTD PMID:21554123 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 decreases expression
decreases secretion		 ISO 4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA
4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein		 CTD PMID:21554123 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
trans-stilbene-4,4'-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP 4,4'-dihydroxystilbene binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CCNA2 mRNA CTD PMID:19496085 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ctsd cathepsin D increases expression ISO 4,4'-dihydroxystilbene results in increased expression of CTSD mRNA CTD PMID:19496085 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases activity
decreases expression		 ISO 4,4'-dihydroxystilbene results in decreased activity of ECE1 protein
4,4'-dihydroxystilbene results in decreased expression of ECE1 mRNA		 CTD PMID:21554123 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression		 ISO 4,4'-dihydroxystilbene results in decreased secretion of EDN1 protein
4,4'-dihydroxystilbene results in decreased expression of EDN1 mRNA		 CTD PMID:21554123 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein; fulvestrant inhibits the reaction [4,4'-dihydroxystilbene analog binds to and results in increased activity of ESR1 protein] CTD PMID:19496085 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4,4'-dihydroxystilbene results in increased expression of FOS mRNA CTD PMID:19496085 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Pgr progesterone receptor increases expression ISO 4,4'-dihydroxystilbene results in increased expression of PGR mRNA CTD PMID:19496085 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO 4,4'-dihydroxystilbene binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO 4,4'-dihydroxystilbene results in increased expression of TFF1 mRNA CTD PMID:19496085 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      atom 19878
        nonmetal atom 19800
          carbon atom 19754
            organic molecular entity 19754
              olefinic compound 16972
                stilbene 3403
                  stilbene-4,4'-diol 10
                    3,3'-dimethoxystilbene-4,4'-diol + 0
                    cis-stilbene-4,4'-diol + 0
                    trans-stilbene-4,4'-diol + 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                carbocyclic compound 18584
                                  benzenoid aromatic compound 18008
                                    benzenes 17873
                                      stilbene 3403
                                        stilbene-4,4'-diol 10
                                          3,3'-dimethoxystilbene-4,4'-diol + 0
                                          cis-stilbene-4,4'-diol + 0
                                          trans-stilbene-4,4'-diol + 10
paths to the root