CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1,2,3-Trichloropropane
Accession: CHEBI:34036
browse the term
Definition: An organochlorine compound that has formula C3H5Cl3.
Synonyms: related_synonym: Formula=C3H5Cl3; InChI=1S/C3H5Cl3/c4-1-3(6)2-5/h3H,1-2H2; InChIKey=CFXQEHVMCRXUSD-UHFFFAOYSA-N; SMILES=ClCC(Cl)CCl
xref: CAS:96-18-4; KEGG:C14400
xref_mesh: MESH:C009536
xref: PPDB:1635
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Bche
butyrylcholinesterase
decreases activity
EXP
1,2,3-trichloropropane results in decreased activity of BCHE protein
CTD
PMID:12692652
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases secretion
ISO
1,2,3-trichloropropane results in increased secretion of ENPP2 protein
CTD
PMID:22952646
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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Mmp9
matrix metallopeptidase 9
increases expression
ISO
1,2,3-trichloropropane results in increased expression of MMP9 mRNA; 1,2,3-trichloropropane results in increased expression of MMP9 protein
CTD
PMID:22952646
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases activity
ISO
1,2,3-trichloropropane results in increased activity of NFE2L2 protein
CTD
PMID:30114225 PMID:30203046
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Ppp3ca
protein phosphatase 3 catalytic subunit alpha
multiple interactions
ISO
1,2,3-trichloropropane results in increased cleavage of and results in increased activity of PPP3CA protein
CTD
PMID:22952646
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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Sord
sorbitol dehydrogenase
increases activity
EXP
1,2,3-trichloropropane results in increased activity of SORD protein
CTD
PMID:12692652
NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
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Tnf
tumor necrosis factor
increases expression
ISO
1,2,3-trichloropropane results in increased expression of TNF mRNA
CTD
PMID:22952646
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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