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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alkali metal hydroxide
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Accession:CHEBI:33978 term browser browse the term
Synonyms:related_synonym: alkali metal base;   alkali metal bases;   alkali metal hydroxides


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potassium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 increases expression ISO potassium hydroxide results in increased expression of CFL1 mRNA; potassium hydroxide results in increased expression of CFL1 protein CTD PMID:21469165 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression		 ISO potassium hydroxide results in decreased expression of and affects the localization of HSPB1 protein
potassium hydroxide results in increased expression of HSPB1 mRNA		 CTD PMID:21469165 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO potassium hydroxide results in increased expression of and results in increased secretion of IL1A protein CTD PMID:21469165 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression		 ISO potassium hydroxide results in increased expression of SOD1 mRNA
potassium hydroxide results in decreased expression of SOD1 protein		 CTD PMID:21469165 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
sodium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression		 EXP lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of ACTA2 protein] CTD PMID:38202631 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions		 EXP Sodium Hydroxide results in increased expression of CASP3 mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of CASP3 mRNA]		 CTD PMID:38202631 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions		 EXP Sodium Hydroxide results in increased expression of COL1A2 protein
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of COL1A2 protein]		 CTD PMID:38202631 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression		 EXP lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of COL3A1 protein] CTD PMID:38202631 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Egfr epidermal growth factor receptor affects response to substance ISO EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ezr ezrin increases expression ISO Sodium Hydroxide results in increased expression of EZR mRNA CTD PMID:29893927 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions		 EXP Sodium Hydroxide results in increased expression of FN1 protein
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of FN1 protein]		 CTD PMID:38202631 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Ier3 immediate early response 3 affects response to substance ISO IER3 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Sodium Hydroxide results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il22 interleukin 22 affects response to substance ISO IL22 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 EXP Sodium Hydroxide results in increased expression of JUN mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of JUN mRNA]		 CTD PMID:38202631 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 increases activity
decreases response to substance		 ISO Sodium Hydroxide results in increased activity of KCNK3 protein
KCNK3 protein mutant form results in decreased susceptibility to Sodium Hydroxide		 CTD PMID:30365877 NCBI chr 6:25,761,487...25,799,153
Ensembl chr 6:25,763,228...25,799,153 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions		 EXP Sodium Hydroxide results in increased expression of MMP9 mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of MMP9 mRNA]		 CTD PMID:38202631 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects response to substance ISO HLA-G SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Trim10 tripartite motif-containing 10 affects response to substance ISO TRIM10 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,689,554...1,698,948
Ensembl chr20:1,689,562...1,698,252 		JBrowse link
G Trim31 tripartite motif-containing 31 affects response to substance ISO TRIM31 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,653,165...1,666,494
Ensembl chr20:1,653,165...1,666,494 		JBrowse link
G Trim40 tripartite motif-containing 40 affects response to substance ISO TRIM40 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,676,114...1,685,906
Ensembl chr20:1,676,270...1,685,214 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      atom 19872
        main group element atom 19811
          alkali metal atom 14345
            alkali metal molecular entity 14332
              alkali metal hydroxide 22
                caesium hydroxide 0
                lithium hydroxide 0
                potassium hydroxide 4
                rubidium hydroxide 0
                sodium hydroxide 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      chalcogen 19563
                        oxygen atom 19535
                          oxygen molecular entity 19535
                            hydroxides 19341
                              inorganic hydroxy compound 766
                                metallic base 38
                                  alkali metal hydroxide 22
                                    caesium hydroxide 0
                                    lithium hydroxide 0
                                    potassium hydroxide 4
                                    rubidium hydroxide 0
                                    sodium hydroxide 18
paths to the root