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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alkali metal hydroxide
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Accession:CHEBI:33978 term browser browse the term
Synonyms:related_synonym: alkali metal base;   alkali metal bases;   alkali metal hydroxides


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potassium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 increases expression ISO potassium hydroxide results in increased expression of CFL1 mRNA; potassium hydroxide results in increased expression of CFL1 protein CTD PMID:21469165 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression 		ISO potassium hydroxide results in decreased expression of and affects the localization of HSPB1 protein
potassium hydroxide results in increased expression of HSPB1 mRNA 		CTD PMID:21469165 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO potassium hydroxide results in increased expression of and results in increased secretion of IL1A protein CTD PMID:21469165 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression 		ISO potassium hydroxide results in increased expression of SOD1 mRNA
potassium hydroxide results in decreased expression of SOD1 protein 		CTD PMID:21469165 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
sodium hydroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression 		EXP lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of ACTA2 protein] CTD PMID:38202631 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions 		EXP Sodium Hydroxide results in increased expression of CASP3 mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of CASP3 mRNA] 		CTD PMID:38202631 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions 		EXP Sodium Hydroxide results in increased expression of COL1A2 protein
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of COL1A2 protein] 		CTD PMID:38202631 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression 		EXP lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of COL3A1 protein] CTD PMID:38202631 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Egfr epidermal growth factor receptor affects response to substance ISO EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Ezr ezrin increases expression ISO Sodium Hydroxide results in increased expression of EZR mRNA CTD PMID:29893927 NCBI chr 1:49,373,033...49,416,573
Ensembl chr 1:49,373,035...49,416,573 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions 		EXP Sodium Hydroxide results in increased expression of FN1 protein
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of FN1 protein] 		CTD PMID:38202631 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Ier3 immediate early response 3 affects response to substance ISO IER3 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Sodium Hydroxide results in increased expression of IL1B protein CTD PMID:29953848 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il22 interleukin 22 affects response to substance ISO IL22 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr 7:55,687,061...55,691,526
Ensembl chr 7:55,686,896...55,692,201 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		EXP Sodium Hydroxide results in increased expression of JUN mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of JUN mRNA] 		CTD PMID:38202631 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 increases activity
decreases response to substance 		ISO Sodium Hydroxide results in increased activity of KCNK3 protein
KCNK3 protein mutant form results in decreased susceptibility to Sodium Hydroxide 		CTD PMID:30365877 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:31,483,140...31,519,061 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions 		EXP Sodium Hydroxide results in increased expression of MMP9 mRNA
lycium barbarum polysaccharide inhibits the reaction [Sodium Hydroxide results in increased expression of MMP9 mRNA] 		CTD PMID:38202631 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects response to substance ISO HLA-G SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
G Trim10 tripartite motif-containing 10 affects response to substance ISO TRIM10 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,694,771...1,703,724
Ensembl chr20:1,694,779...1,703,469 		JBrowse link
G Trim31 tripartite motif-containing 31 affects response to substance ISO TRIM31 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,658,386...1,671,711 		JBrowse link
G Trim40 tripartite motif-containing 40 affects response to substance ISO TRIM40 SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27258892 NCBI chr20:1,680,554...1,691,123
Ensembl chr20:1,681,333...1,691,123 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      atom 20872
        main group element atom 20796
          alkali metal atom 15238
            alkali metal molecular entity 15228
              alkali metal hydroxide 22
                caesium hydroxide 0
                lithium hydroxide 0
                potassium hydroxide 4
                rubidium hydroxide 0
                sodium hydroxide 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      chalcogen 20489
                        oxygen atom 20437
                          oxygen molecular entity 20437
                            hydroxides 19922
                              inorganic hydroxy compound 773
                                metallic base 38
                                  alkali metal hydroxide 22
                                    caesium hydroxide 0
                                    lithium hydroxide 0
                                    potassium hydroxide 4
                                    rubidium hydroxide 0
                                    sodium hydroxide 18
paths to the root