CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: carbendazim
Accession: CHEBI:3392
browse the term
Definition: A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables.
Synonyms: exact_synonym: methyl 1H-benzimidazol-2-ylcarbamate
related_synonym: 1H-benzimidazol-2-ylcarbamic acid methyl ester; 2-(Methoxy-carbonylamino)-benzimidazol; 2-(methoxycarbonylamino)benzimidazole; 2-benzimidazolecarbamic acid methyl ester; BMC; Formula=C9H9N3O2; InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13); InChIKey=TWFZGCMQGLPBSX-UHFFFAOYSA-N; MBC; Mecarzole; SMILES=COC(=O)Nc1nc2ccccc2[nH]1; carbendazime; methyl 2-benzimidazolecarbamate; methyl benzimidazol-2-ylcarbamate
xref: CAS:10605-21-7; HMDB:HMDB0031769; KEGG:C10897
xref_mesh: MESH:C006698
xref: PMID:20833408; PMID:21315898; PMID:22077925; PMID:22903170; PPDB:116; Patent:US3010968; Pesticides:carbendazim; Reaxys:649044; Wikipedia:Carbendazim
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Abi2
abl-interactor 2
increases expression
EXP
carbendazim results in increased expression of ABI2 mRNA
CTD
PMID:22952946
NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
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Acaca
acetyl-CoA carboxylase alpha
increases expression
ISO
carbendazim results in increased expression of ACACA mRNA
CTD
PMID:26071454
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Ache
acetylcholinesterase
multiple interactions
EXP
[carbendazim co-treated with mancozeb] results in increased activity of ACHE protein
CTD
PMID:33217513
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2
increases expression
ISO
carbendazim results in increased expression of AGPAT2 mRNA
CTD
PMID:26071454
NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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Ahr
aryl hydrocarbon receptor
multiple interactions affects localization
ISO
AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein] carbendazim affects the localization of AHR protein
CTD
PMID:27286660
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Alb
albumin
decreases expression
EXP
carbendazim results in decreased expression of ALB protein
CTD
PMID:35437878
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Anxa10
annexin A10
increases expression
ISO
carbendazim results in increased expression of ANXA10 mRNA
CTD
PMID:32194361
NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
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Arg1
arginase 1
decreases expression
ISO
carbendazim results in decreased expression of ARG1 mRNA
CTD
PMID:32194361
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Bag1
BAG cochaperone 1
increases expression
EXP
carbendazim results in increased expression of BAG1 mRNA
CTD
PMID:22952946
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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Bax
BCL2 associated X, apoptosis regulator
increases expression
EXP
carbendazim results in increased expression of BAX mRNA; carbendazim results in increased expression of BAX protein
CTD
PMID:35437878 PMID:35513110
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
EXP
carbendazim results in decreased expression of BCL2 mRNA
CTD
PMID:35437878 PMID:35513110
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l14
Bcl2-like 14
increases expression
EXP
carbendazim results in increased expression of BCL2L14 mRNA
CTD
PMID:22952946
NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
increases activity
ISO
carbendazim results in increased activity of BUB1B protein
CTD
PMID:37506866
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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Casp3
caspase 3
increases activity increases expression multiple interactions
ISO EXP
carbendazim results in increased activity of CASP3 protein carbendazim results in increased expression of CASP3 protein Chitosan inhibits the reaction [carbendazim results in increased expression of CASP3 protein]
CTD
PMID:30851412 PMID:35705592
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
decreases activity multiple interactions decreases expression
EXP
carbendazim results in decreased activity of CAT protein [Chlorpyrifos co-treated with carbendazim] results in decreased activity of CAT protein; Chitosan inhibits the reaction [carbendazim results in decreased expression of CAT protein]
CTD
PMID:27268782 PMID:35513110 PMID:35705592
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccnb1
cyclin B1
increases expression
ISO
carbendazim results in increased expression of CCNB1 protein
CTD
PMID:37506866
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Clca2
chloride channel accessory 2
multiple interactions
EXP
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA
CTD
PMID:22382377
NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
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Cldn11
claudin 11
multiple interactions
EXP
[carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein
CTD
PMID:28576679
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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Clu
clusterin
decreases expression increases expression
EXP
carbendazim results in decreased expression of CLU mRNA carbendazim results in increased expression of CLU mRNA
CTD
PMID:22952946 PMID:27466211
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases activity increases expression
ISO
carbendazim results in increased activity of CYP19A1 protein carbendazim results in increased expression of CYP19A1 mRNA
CTD
PMID:14691014
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression multiple interactions
ISO EXP
carbendazim results in increased expression of CYP1A1 mRNA; carbendazim results in increased expression of CYP1A1 protein 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]; salicylamide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]
CTD
PMID:10103034 PMID:21784029 PMID:27286660 PMID:32194361
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
ISO
carbendazim results in increased expression of CYP1A2 mRNA; carbendazim results in increased expression of CYP1A2 protein
CTD
PMID:21784029
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
carbendazim results in increased expression of CYP2B6 mRNA
CTD
PMID:22310298
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases expression
ISO
carbendazim results in decreased expression of CYP2C19 protein
CTD
PMID:32194361
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
decreases activity
ISO
carbendazim results in decreased activity of CYP2D6 protein
CTD
PMID:20183062
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
carbendazim results in increased expression of CYP3A4 mRNA
CTD
PMID:22310298
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression
ISO
carbendazim results in decreased expression of CYP7A1 mRNA; carbendazim results in decreased expression of CYP7A1 protein
CTD
PMID:32194361
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Dgat1
diacylglycerol O-acyltransferase 1
increases expression
ISO
carbendazim results in increased expression of DGAT1 mRNA
CTD
PMID:26071454
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2
diacylglycerol O-acyltransferase 2
increases expression
ISO
carbendazim results in increased expression of DGAT2 mRNA
CTD
PMID:26071454
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Dnaaf11
dynein axonemal assembly factor 11
decreases expression
EXP
carbendazim results in decreased expression of DNAAF11 mRNA
CTD
PMID:27466211
NCBI chr 7:98,141,525...98,245,906
Ensembl chr 7:98,144,763...98,245,837
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Dpp7
dipeptidylpeptidase 7
multiple interactions
EXP
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA
CTD
PMID:22382377
NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
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Esr1
estrogen receptor 1
decreases expression affects localization
EXP ISO
carbendazim results in decreased expression of ESR1 mRNA carbendazim affects the localization of ESR1 protein
CTD
PMID:28576679 PMID:37506866
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
decreases expression
EXP
carbendazim results in decreased expression of ESR2 mRNA
CTD
PMID:28576679
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fabp9
fatty acid binding protein 9
multiple interactions decreases expression
EXP
Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 protein] carbendazim results in decreased expression of FABP9 mRNA; carbendazim results in decreased expression of FABP9 protein
CTD
PMID:33965443
NCBI chr 2:91,591,842...91,595,873
Ensembl chr 2:91,592,298...91,595,873
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Fank1
fibronectin type III and ankyrin repeat domains 1
increases expression
EXP
carbendazim results in increased expression of FANK1 mRNA
CTD
PMID:22952946
NCBI chr 1:188,577,512...188,685,501
Ensembl chr 1:188,577,575...188,685,504
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Foxa2
forkhead box A2
increases expression
ISO
carbendazim results in increased expression of FOXA2 mRNA
CTD
PMID:26071454
NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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Fshb
follicle stimulating hormone subunit beta
decreases expression multiple interactions
EXP
carbendazim results in decreased expression of FSHB protein Carnitine inhibits the reaction [carbendazim results in decreased expression of FSHB protein]
CTD
PMID:33965443
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G6pc1
glucose-6-phosphatase catalytic subunit 1
decreases expression
ISO
carbendazim results in decreased expression of G6PC1 mRNA
CTD
PMID:32194361
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Gfap
glial fibrillary acidic protein
increases expression
EXP
carbendazim results in increased expression of GFAP protein
CTD
PMID:35513110
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Gja1
gap junction protein, alpha 1
multiple interactions
EXP
[carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein
CTD
PMID:28576679
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Got1
glutamic-oxaloacetic transaminase 1
increases secretion multiple interactions
EXP
carbendazim results in increased secretion of GOT1 protein Chitosan inhibits the reaction [carbendazim results in increased secretion of GOT1 protein]
CTD
PMID:35705592
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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Gpt
glutamic--pyruvic transaminase
increases expression multiple interactions increases secretion
EXP
carbendazim results in increased expression of GPT protein Chitosan inhibits the reaction [carbendazim results in increased secretion of GPT protein]
CTD
PMID:35437878 PMID:35705592
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Hmox1
heme oxygenase 1
multiple interactions decreases expression
EXP
Chitosan inhibits the reaction [carbendazim results in decreased expression of HMOX1 mRNA]
CTD
PMID:35705592
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Ift81
intraflagellar transport 81
decreases expression
EXP
carbendazim results in decreased expression of IFT81 mRNA
CTD
PMID:22952946 PMID:27466211
NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
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Il10
interleukin 10
multiple interactions decreases expression
EXP
Carnitine inhibits the reaction [carbendazim results in decreased expression of IL10 protein]
CTD
PMID:33965443
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1b
interleukin 1 beta
increases expression
ISO EXP
carbendazim results in increased expression of IL1B mRNA; carbendazim results in increased expression of IL1B protein
CTD
PMID:26071454 PMID:35513110
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
increases expression multiple interactions
ISO EXP
carbendazim results in increased expression of IL6 mRNA; carbendazim results in increased expression of IL6 protein Carnitine inhibits the reaction [carbendazim results in increased expression of IL6 protein]
CTD
PMID:26071454 PMID:33965443
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Itga5
integrin subunit alpha 5
decreases expression
ISO
carbendazim results in decreased expression of ITGA5 mRNA
CTD
PMID:25530041
NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
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Itgb1
integrin subunit beta 1
decreases expression
ISO
carbendazim results in decreased expression of ITGB1 mRNA
CTD
PMID:25530041
NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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Keap1
Kelch-like ECH-associated protein 1
multiple interactions increases expression
EXP
Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA]
CTD
PMID:35705592
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Lhb
luteinizing hormone subunit beta
decreases expression multiple interactions
EXP
carbendazim results in decreased expression of LHB protein Carnitine inhibits the reaction [carbendazim results in decreased expression of LHB protein]
CTD
PMID:33965443
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Loxl1
lysyl oxidase-like 1
multiple interactions increases expression
EXP
2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA
CTD
PMID:22382377
NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
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Lpl
lipoprotein lipase
decreases expression
ISO
carbendazim results in decreased expression of LPL protein
CTD
PMID:30496565
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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Macrod1
mono-ADP ribosylhydrolase 1
multiple interactions
EXP
[carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA
CTD
PMID:22382377
NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716
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Mapk1
mitogen activated protein kinase 1
affects localization
ISO
carbendazim affects the localization of MAPK1 protein modified form
CTD
PMID:37506866
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
affects localization
ISO
carbendazim affects the localization of MAPK3 protein modified form
CTD
PMID:37506866
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
increases expression
EXP
carbendazim results in increased expression of MAPK8 mRNA
CTD
PMID:35513110
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mfap3l
microfibril associated protein 3 like
increases expression
EXP
carbendazim results in increased expression of MFAP3L mRNA
CTD
PMID:22952946
NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
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Mir128-1
microRNA 128-1
increases expression
EXP
carbendazim results in increased expression of MIR128-1 mRNA
CTD
PMID:32418910
NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530
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Mir423
microRNA 423
increases expression
EXP
carbendazim results in increased expression of MIR423 mRNA
CTD
PMID:32418910
NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
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Mmp2
matrix metallopeptidase 2
decreases expression
ISO
carbendazim results in decreased expression of MMP2 mRNA
CTD
PMID:25530041
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp9
matrix metallopeptidase 9
decreases expression
ISO
carbendazim results in decreased expression of MMP9 mRNA
CTD
PMID:25530041
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mpo
myeloperoxidase
multiple interactions increases activity
EXP
[Chlorpyrifos co-treated with carbendazim] results in increased activity of MPO protein carbendazim results in increased activity of MPO protein
CTD
PMID:27268782
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression decreases expression multiple interactions
ISO EXP
carbendazim results in increased expression of NFE2L2 protein carbendazim results in decreased expression of NFE2L2 mRNA Chitosan inhibits the reaction [carbendazim results in decreased expression of NFE2L2 mRNA]
CTD
PMID:30851412 PMID:35705592
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nos2
nitric oxide synthase 2
multiple interactions increases expression
EXP
Carnitine inhibits the reaction [carbendazim results in increased expression of NOS2 protein]; Chitosan inhibits the reaction [carbendazim results in increased expression of NOS2 protein]
CTD
PMID:33965443 PMID:35705592
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
ISO
carbendazim inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein]
CTD
PMID:25257666
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Ocln
occludin
decreases expression multiple interactions
EXP
carbendazim results in decreased expression of OCLN protein Carnitine inhibits the reaction [carbendazim results in decreased expression of OCLN protein]
CTD
PMID:33965443
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Pim1
Pim-1 proto-oncogene, serine/threonine kinase
increases expression
EXP
carbendazim results in increased expression of PIM1 mRNA
CTD
PMID:22952946
NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
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Plau
plasminogen activator, urokinase
decreases expression
ISO
carbendazim results in decreased expression of PLAU mRNA
CTD
PMID:25530041
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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Ptgds
prostaglandin D2 synthase
decreases expression
EXP
carbendazim results in decreased expression of PTGDS mRNA
CTD
PMID:22952946
NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
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Pttg1
PTTG1 regulator of sister chromatid separation, securin
increases expression
ISO
carbendazim results in increased expression of PTTG1 protein
CTD
PMID:37506866
NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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Rela
RELA proto-oncogene, NF-kB subunit
increases expression multiple interactions
EXP
carbendazim results in increased expression of RELA protein Carnitine inhibits the reaction [carbendazim results in increased expression of RELA protein]
CTD
PMID:33965443
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Serpine2
serpin family E member 2
increases expression
ISO
carbendazim results in increased expression of SERPINE2 mRNA
CTD
PMID:25530041
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Shank3
SH3 and multiple ankyrin repeat domains 3
multiple interactions
EXP
[carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA
CTD
PMID:22382377
NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
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Sil1
SIL1 nucleotide exchange factor
decreases expression
EXP
carbendazim results in decreased expression of SIL1 mRNA
CTD
PMID:22952946 PMID:27466211
NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332
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Sod3
superoxide dismutase 3
increases expression
EXP
carbendazim results in increased expression of SOD3 mRNA
CTD
PMID:27466211
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
ISO
carbendazim results in increased expression of SREBF1 mRNA
CTD
PMID:26071454
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Star
steroidogenic acute regulatory protein
decreases expression multiple interactions
EXP
carbendazim results in decreased expression of STAR mRNA; carbendazim results in decreased expression of STAR protein Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR protein]
CTD
PMID:33965443
NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Tbc1d5
TBC1 domain family, member 5
decreases expression
EXP
carbendazim results in decreased expression of TBC1D5 mRNA
CTD
PMID:27466211
NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
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Timp1
TIMP metallopeptidase inhibitor 1
increases expression
ISO
carbendazim results in increased expression of TIMP1 mRNA
CTD
PMID:25530041
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression
ISO
carbendazim results in increased expression of TIMP2 mRNA
CTD
PMID:25530041
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tnf
tumor necrosis factor
multiple interactions increases expression
EXP
Carnitine inhibits the reaction [carbendazim results in increased expression of TNF protein]
CTD
PMID:33965443 PMID:35437878 PMID:35513110
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnp1
transition protein 1
increases expression
EXP
carbendazim results in increased expression of TNP1 mRNA
CTD
PMID:28576679
NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
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Tnp2
transition protein 2
increases expression
EXP
carbendazim results in increased expression of TNP2 mRNA
CTD
PMID:28576679
NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538
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Tp53
tumor protein p53
increases expression affects activity
EXP ISO
carbendazim results in increased expression of TP53 mRNA carbendazim affects the activity of TP53 protein
CTD
PMID:35435491 PMID:35513110
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Tshb
thyroid stimulating hormone subunit beta
increases expression
EXP
carbendazim results in increased expression of TSHB protein
CTD
PMID:33965443
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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