CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: tungsten molecular entity
Accession: CHEBI:33742
browse the term
Synonyms: related_synonym: tungsten compounds; tungsten molecular entities
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Akt2
AKT serine/threonine kinase 2
affects expression
ISO
sodium tungstate(VI) affects the expression of AKT2 mRNA
CTD
PMID:26164860
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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Ccn2
cellular communication network factor 2
decreases expression
ISO
sodium tungstate(VI) results in decreased expression of CCN2 mRNA
CTD
PMID:26164860
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Cd74
CD74 molecule
increases expression
ISO
sodium tungstate(VI) results in increased expression of CD74 mRNA
CTD
PMID:26164860
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
decreases expression
ISO
sodium tungstate(VI) results in decreased expression of CDKN1A mRNA
CTD
PMID:26164860
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cryab
crystallin, alpha B
increases expression
ISO
sodium tungstate(VI) results in increased expression of CRYAB mRNA
CTD
PMID:26164860
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Csf3
colony stimulating factor 3
increases expression
ISO
sodium tungstate(VI) results in increased expression of CSF3 mRNA
CTD
PMID:26164860
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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Egr1
early growth response 1
increases expression
EXP
sodium tungstate(VI) results in increased expression of EGR1 mRNA
CTD
PMID:24619124
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Fbxw5
F-box and WD repeat domain containing 5
decreases expression
EXP
sodium tungstate(VI) results in decreased expression of FBXW5 mRNA
CTD
PMID:24619124
NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092
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Fn3k
fructosamine 3 kinase
increases expression
EXP
sodium tungstate(VI) results in increased expression of FN3K mRNA
CTD
PMID:24619124
NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895
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Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]
CTD
PMID:11357483
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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Hoxb5
homeo box B5
decreases expression
ISO
sodium tungstate(VI) results in decreased expression of HOXB5 mRNA
CTD
PMID:26164860
NCBI chr10:81,269,372...81,271,580
Ensembl chr10:81,269,372...81,271,580
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Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
sodium tungstate(VI) results in increased expression of HTATIP2 mRNA
CTD
PMID:26164860
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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Igfbp2
insulin-like growth factor binding protein 2
affects expression
ISO
sodium tungstate(VI) affects the expression of IGFBP2 mRNA
CTD
PMID:26164860
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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Nmt2
N-myristoyltransferase 2
increases expression
EXP
sodium tungstate(VI) results in increased expression of NMT2 mRNA
CTD
PMID:24619124
NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
sodium tungstate(VI) results in increased expression of NQO1 mRNA
CTD
PMID:26164860
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Ptpn1
protein tyrosine phosphatase, non-receptor type 1
multiple interactions
ISO
[sodium tungstate(VI) results in increased abundance of Tungsten] which results in decreased activity of PTPN1 protein
CTD
PMID:34320920
NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
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S100a4
S100 calcium-binding protein A4
increases expression
ISO
sodium tungstate(VI) results in increased expression of S100A4 mRNA
CTD
PMID:26164860
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
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Skp2
S-phase kinase associated protein 2
increases expression
ISO
sodium tungstate(VI) results in increased expression of SKP2 mRNA
CTD
PMID:26164860
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
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Stk26
serine/threonine kinase 26
increases expression
ISO
sodium tungstate(VI) results in increased expression of STK26 mRNA
CTD
PMID:26164860
NCBI chr X:130,325,064...130,375,674
Ensembl chr X:130,310,885...130,374,291
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Tgfb1
transforming growth factor, beta 1
decreases expression
ISO
sodium tungstate(VI) results in decreased expression of TGFB1 mRNA
CTD
PMID:26164860
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfb2
transforming growth factor, beta 2
affects expression
ISO
sodium tungstate(VI) affects the expression of TGFB2 mRNA
CTD
PMID:26164860
NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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Xdh
xanthine dehydrogenase
multiple interactions
EXP ISO
sodium tungstate(VI) inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] [sodium tungstate(VI) results in increased abundance of Tungsten] which results in decreased activity of XDH protein
CTD
PMID:17727797 PMID:34320920
NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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Aox1
aldehyde oxidase 1
decreases expression multiple interactions
ISO
tungstate results in decreased expression of AOX1 protein tungstate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AOX1 protein]
CTD
PMID:15664268
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
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Car1
carbonic anhydrase 1
decreases activity
ISO
tungstate results in decreased activity of CA1 protein
CTD
PMID:15664814
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
tungstate results in decreased activity of CA2 protein
CTD
PMID:15664814
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car4
carbonic anhydrase 4
decreases activity
ISO
tungstate results in decreased activity of CA4 protein
CTD
PMID:15664814
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Car5a
carbonic anhydrase 5A
decreases activity
ISO
tungstate results in decreased activity of CA5A protein
CTD
PMID:15664814
NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
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Car9
carbonic anhydrase 9
decreases activity
ISO
tungstate results in decreased activity of CA9 protein
CTD
PMID:15664814
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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G6pc1
glucose-6-phosphatase catalytic subunit 1
multiple interactions
EXP
tungstate inhibits the reaction [Glucose results in increased activity of G6PC1 protein]
CTD
PMID:16920846
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Ivl
involucrin
decreases expression
ISO
tungstate results in decreased expression of IVL protein
CTD
PMID:7848924
NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
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Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
multiple interactions
ISO
PAPSS1 protein binds to and affects the metabolism of tungstate
CTD
PMID:15065880
NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395
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Slc34a2
solute carrier family 34 member 2
multiple interactions
EXP
tungstate promotes the reaction [Fructose results in decreased expression of SLC34A2 mRNA]
CTD
PMID:18400728
NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
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