CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | carbohydrate acid |
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Accession: | CHEBI:33720
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browse the term
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Synonyms: | related_synonym: | carbohydrate acids |
| cyclic_relationship: | is_conjugate_acid_of CHEBI:33721 |
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Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
[CYP3A4 protein results in increased glucuronidation of 1-hydroxymethylmidazolam] which results in increased abundance of 1-hydroxymethylmidazolam glucuronide |
CTD |
PMID:27485346 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Abca8 |
ATP binding cassette subfamily A member 8 |
increases uptake multiple interactions |
ISO |
ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Digoxin inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; dofequidar inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; ochratoxin A inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Probenecid inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Verapamil inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] |
CTD |
PMID:12379217 |
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NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
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Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity decreases secretion affects localization multiple interactions |
EXP |
estradiol-17 beta-glucuronide results in decreased activity of ABCB11 protein estradiol-17 beta-glucuronide results in decreased secretion of ABCB11 protein estradiol-17 beta-glucuronide affects the localization of ABCB11 protein estradiol-17 beta-glucuronide affects the localization of and affects the activity of ABCB11 protein; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; wortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein] |
CTD |
PMID:10869290 PMID:12702498 PMID:12893835 PMID:15763547 PMID:18972403 PMID:20815017 PMID:29090346 More...
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a |
ATP binding cassette subfamily B member 1A |
affects response to substance multiple interactions increases transport |
ISO EXP |
ABCB1 affects the susceptibility to estradiol-17 beta-glucuronide Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]; estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]; estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide] |
CTD |
PMID:9794924 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb4 |
ATP binding cassette subfamily B member 4 |
affects export |
ISO |
ABCB4 protein affects the export of estradiol-17 beta-glucuronide |
CTD |
PMID:11302927 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc1 |
ATP binding cassette subfamily C member 1 |
affects transport increases export multiple interactions increases uptake increases transport |
ISO |
ABCC1 protein affects the transport of estradiol-17 beta-glucuronide ABCC1 protein results in increased export of estradiol-17 beta-glucuronide [Glutathione co-treated with Apigenin] affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; [Glutathione co-treated with naringenin] inhibits the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; BAY u9773 inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; BAY u9773 inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide]; estradiol-17 beta-glucuronide inhibits the reaction [ABCC1 protein affects the transport of Leukotriene C4]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; estradiol-17 beta-glucuronide inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; kaempferol affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Quercetin affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; S-decylglutathione inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; S-decylglutathione inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide] ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide; ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide |
CTD |
PMID:11278867 PMID:11306701 PMID:15459206 PMID:18336795 PMID:21918036 PMID:27297967 More...
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcc2 |
ATP binding cassette subfamily C member 2 |
affects export multiple interactions affects transport affects response to substance increases transport affects localization decreases secretion |
ISO EXP |
ABCC2 protein affects the export of estradiol-17 beta-glucuronide [Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of estradiol-17 beta-glucuronide; [SLCO1B1 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; [SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Bile Acids and Salts promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; estradiol-17 beta-glucuronide promotes the reaction [ABCC2 protein affects the transport of Bile Acids and Salts]; estradiol-17 beta-glucuronide results in decreased activity of and affects the localization of ABCC2 protein; Ethinyl Estradiol metabolite promotes the reaction [ABCC2 protein results in increased uptake of estradiol-17 beta-glucuronide]; Furosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Indomethacin promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Pantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; sulfanitran promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide] ABCC2 protein affects the susceptibility to estradiol-17 beta-glucuronide ABCC2 protein modified form results in increased transport of estradiol-17 beta-glucuronide; ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide abietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]; AG 1879 inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; Bucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; CL 387785 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; EGF protein inhibits the reaction [Fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]; EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein; Fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Protein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Wortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein] estradiol-17 beta-glucuronide results in decreased secretion of ABCC2 protein |
CTD |
PMID:11500505 PMID:12029626 PMID:12642476 PMID:12702498 PMID:12702717 PMID:12704183 PMID:12893835 PMID:14722317 PMID:15652233 PMID:15846474 PMID:15901800 PMID:15904671 PMID:17463180 PMID:18180276 PMID:18436619 PMID:18972403 PMID:19628752 PMID:20815017 PMID:25813982 PMID:29052767 PMID:29090346 PMID:32003934 More...
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3 |
ATP binding cassette subfamily C member 3 |
affects transport multiple interactions increases transport increases activity |
ISO |
ABCC3 protein affects the transport of estradiol-17 beta-glucuronide Bile Acids and Salts inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Ethinyl Estradiol metabolite promotes the reaction [ABCC3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Furosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Indomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; resveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]; resveratrol-4'-O-glucuronide inhibits the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide] estradiol-17 beta-glucuronide results in increased activity of ABCC3 protein |
CTD |
PMID:12704183 PMID:14722317 PMID:17569508 PMID:19114588 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4 |
ATP binding cassette subfamily C member 4 |
increases transport affects export increases export |
ISO |
ABCC4 protein results in increased transport of estradiol-17 beta-glucuronide ABCC4 gene SNP affects the export of estradiol-17 beta-glucuronide ABCC4 protein results in increased export of estradiol-17 beta-glucuronide |
CTD |
PMID:11856762 PMID:27659809 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcg2 |
ATP binding cassette subfamily G member 2 |
increases transport multiple interactions |
ISO |
ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]; lapatinib inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide] |
CTD |
PMID:18436619 PMID:18829547 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
EXP |
estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:29090346 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Aqp8 |
aquaporin 8 |
decreases expression |
EXP |
estradiol-17 beta-glucuronide results in decreased expression of AQP8 protein |
CTD |
PMID:17110522 |
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NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
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Egf |
epidermal growth factor |
multiple interactions |
EXP |
EGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]] |
CTD |
PMID:25813982 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Egfr |
epidermal growth factor receptor |
multiple interactions |
EXP |
EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of EGFR protein; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of EGFR protein] |
CTD |
PMID:25813982 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Esr1 |
estrogen receptor 1 |
multiple interactions |
EXP |
estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of ESR1 protein |
CTD |
PMID:25813982 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Hgf |
hepatocyte growth factor |
multiple interactions increases uptake |
EXP |
[HGF protein results in increased expression of SLCO1A1 protein] which results in increased uptake of estradiol-17 beta-glucuronide; ochratoxin A inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; Ouabain inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; SLCO1A1 protein affects the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; Sulfobromophthalein inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide] |
CTD |
PMID:18031729 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions increases phosphorylation |
EXP |
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of IGF1R protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein] |
CTD |
PMID:29090346 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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Ocln |
occludin |
affects localization |
EXP |
estradiol-17 beta-glucuronide affects the localization of OCLN protein |
CTD |
PMID:17463180 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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Prkca |
protein kinase C, alpha |
multiple interactions affects localization |
EXP |
Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of PRKCA protein] |
CTD |
PMID:18972403 |
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NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions affects transport |
EXP ISO |
estradiol-17 beta-glucuronide inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine] SLC22A8 protein affects the transport of estradiol-17 beta-glucuronide |
CTD |
PMID:11306713 PMID:15319347 |
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NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
affects uptake increases uptake multiple interactions |
ISO EXP |
SLCO1A4 protein affects the uptake of estradiol-17 beta-glucuronide SLCO1A2 protein results in increased uptake of estradiol-17 beta-glucuronide Bile Acids and Salts inhibits the reaction [SLCO1A2 protein results in increased uptake of estradiol-17 beta-glucuronide] |
CTD |
PMID:19464309 PMID:21561886 |
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NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
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Slco1b2 |
solute carrier organic anion transporter family member 1B2 |
increases uptake increases import multiple interactions affects response to substance |
EXP ISO |
SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide SLCO1B3 results in increased import of estradiol-17 beta-glucuronide 2,2',4,4',5,6'-hexabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; [SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; pentabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide] SLCO1B2 protein affects the susceptibility to estradiol-17 beta-glucuronide Bile Acids and Salts inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide] |
CTD |
PMID:18180276 PMID:18296417 PMID:19464309 PMID:20176623 PMID:32003934 PMID:32305507 PMID:34619012 More...
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NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
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Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions |
EXP |
estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein; Protein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein] |
CTD |
PMID:25813982 |
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NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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Tjp1 |
tight junction protein 1 |
affects localization |
EXP |
estradiol-17 beta-glucuronide affects the localization of TJP1 protein |
CTD |
PMID:17463180 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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Abcb11 |
ATP binding cassette subfamily B member 11 |
decreases activity |
EXP |
estradiol-3-glucuronide results in decreased activity of ABCB11 protein |
CTD |
PMID:10869290 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Kl |
Klotho |
multiple interactions increases hydrolysis |
ISO |
estradiol-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] KL protein results in increased hydrolysis of estradiol-3-glucuronide |
CTD |
PMID:14701853 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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Arf6 |
ARF GTPase 6 |
multiple interactions |
ISO |
2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] |
CTD |
PMID:10931844 |
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NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases activity |
ISO |
2,3-Diphosphoglycerate results in decreased activity of BGLAP protein |
CTD |
PMID:16857255 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Pld1 |
phospholipase D1 |
decreases activity |
ISO |
2,3-Diphosphoglycerate results in decreased activity of PLD1 protein |
CTD |
PMID:16857255 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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Sts |
steroid sulfatase |
multiple interactions |
ISO |
2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] |
CTD |
PMID:16178010 |
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NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
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G |
Arf6 |
ARF GTPase 6 |
multiple interactions |
ISO |
2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] |
CTD |
PMID:10931844 |
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NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases activity |
ISO |
2,3-Diphosphoglycerate results in decreased activity of BGLAP protein |
CTD |
PMID:16857255 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Pld1 |
phospholipase D1 |
decreases activity |
ISO |
2,3-Diphosphoglycerate results in decreased activity of PLD1 protein |
CTD |
PMID:16857255 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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Sts |
steroid sulfatase |
multiple interactions |
ISO |
2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] |
CTD |
PMID:16178010 |
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NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
EXP |
[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog] |
CTD |
PMID:15788719 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 3-phosphoglycerate] |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Mapt |
microtubule-associated protein tau |
multiple interactions |
ISO |
[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate; PF-06840003 inhibits the reaction [[amyloid beta-protein (1-42) binds to MAPT protein] which results in decreased abundance of 3-phosphoglycerate] |
CTD |
PMID:39172838 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Ugt1a1 |
UDP glucuronosyltransferase family 1 member A1 |
multiple interactions |
ISO |
[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; [UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; belinostat inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Diclofenac inhibits the reaction [[UGT1A1 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] |
CTD |
PMID:31812603 PMID:33290829 |
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NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
multiple interactions |
ISO |
[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; [UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; Androsterone inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [[UGT1A3 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] |
CTD |
PMID:31812603 PMID:33290829 |
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NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a6 |
UDP glucuronosyltransferase family 1 member A6 |
multiple interactions |
ISO |
[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; [UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; belinostat inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; Diclofenac inhibits the reaction [[UGT1A6 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] |
CTD |
PMID:31812603 PMID:33290829 |
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NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
multiple interactions |
ISO |
[UGT1A9 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; [UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; Diclofenac inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] |
CTD |
PMID:31812603 PMID:33290829 |
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NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Ugt2b1 |
UDP glucuronosyltransferase 2 family, polypeptide B1 |
multiple interactions |
ISO |
[UGT2B17 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide |
CTD |
PMID:33290829 |
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NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
multiple interactions |
ISO |
[UGT2B7 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; [UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; Androsterone inhibits the reaction [[UGT2B7 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; belinostat inhibits the reaction [[UGT2B7 protein results in increased glucuronidation of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide]; pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] |
CTD |
PMID:31812603 PMID:33290829 |
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NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
4-nitrophenylglucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] |
CTD |
PMID:11856762 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Ugt2b15 |
UDP glucuronosyltransferase family 2 member B15 |
increases abundance |
EXP |
UGT2B15 protein results in increased abundance of 7-hydroxycoumarin glucuronide |
CTD |
PMID:7574722 |
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NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
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G |
Cmas |
cytidine monophosphate N-acetylneuraminic acid synthetase |
affects abundance |
ISO |
CMAS protein affects the abundance of N-Acetylneuraminic Acid; CMAS protein affects the abundance of N-Acetylneuraminic Acid analog |
CTD |
PMID:27380425 |
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NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
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G |
Gne |
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
increases chemical synthesis |
EXP |
GNE protein results in increased chemical synthesis of N-Acetylneuraminic Acid |
CTD |
PMID:9305888 |
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NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499
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G |
Nans |
N-acetylneuraminate synthase |
increases chemical synthesis |
ISO |
NANS results in increased chemical synthesis of N-Acetylneuraminic Acid |
CTD |
PMID:27213289 |
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NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
increases activity multiple interactions affects export |
ISO EXP |
acetaminophen glucuronide results in increased activity of ABCC3 protein Ethinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide] ABCC3 protein affects the export of acetaminophen glucuronide |
CTD |
PMID:16250050 PMID:16554369 PMID:17569508 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Ins2 |
insulin 2 |
increases abundance |
ISO |
INS protein results in increased abundance of acetaminophen glucuronide |
CTD |
PMID:26739624 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
multiple interactions |
ISO |
OGT gene mutant form inhibits the reaction [Acetaminophen results in increased abundance of acetaminophen glucuronide] |
CTD |
PMID:29325178 |
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NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Ugt2b7 |
UDP glucuronosyltransferase family 2 member B7 |
multiple interactions increases chemical synthesis |
ISO |
alclofenac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; cicloprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Diclofenac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Diflunisal inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Fenoprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ibuprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Indomethacin inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketoprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketorolac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Meclofenamic Acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Mefenamic Acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Naproxen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; pirprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; tiaprofenic acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide] |
CTD |
PMID:19740398 |
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NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
multiple interactions |
ISO |
naphthyl glucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] |
CTD |
PMID:11856762 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Kl |
Klotho |
multiple interactions |
ISO |
androsterone glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] |
CTD |
PMID:14701853 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Ache |
acetylcholinesterase |
multiple interactions increases expression |
EXP |
baicalin results in increased expression of and results in increased activity of ACHE protein baicalin results in increased expression of ACHE mRNA |
CTD |
PMID:27019979 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Ahr |
aryl hydrocarbon receptor |
increases activity |
ISO |
baicalin results in increased activity of AHR protein |
CTD |
PMID:17869316 PMID:26204831 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] |
CTD |
PMID:38016618 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Alb |
albumin |
multiple interactions |
ISO |
baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of ALB protein] |
CTD |
PMID:35088608 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
EXP |
baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] |
CTD |
PMID:20139896 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Angpt1 |
angiopoietin 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] |
CTD |
PMID:34414639 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Atf2 |
activating transcription factor 2 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] |
CTD |
PMID:24312512 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
baicalin results in increased expression of BAX protein baicalin affects the reaction [Rotenone results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Rotenone results in increased expression of BAX protein] baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX protein] baicalin inhibits the reaction [Rotenone affects the expression of BAX protein] |
CTD |
PMID:21457722 PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 PMID:36446982 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein] baicalin results in decreased expression of BCL2 protein baicalin affects the reaction [Rotenone results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Rotenone results in decreased expression of BCL2 protein] baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein] |
CTD |
PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 PMID:36446982 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]] |
CTD |
PMID:38016618 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
multiple interactions |
EXP ISO |
baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein] baicalin affects the reaction [Rotenone results in decreased activity of CASP3 protein] baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; baicalin inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein] |
CTD |
PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 PMID:36446982 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cat |
catalase |
multiple interactions |
ISO |
baicalin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein] |
CTD |
PMID:34333357 PMID:35088608 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccna2 |
cyclin A2 |
decreases expression |
ISO |
baicalin results in decreased expression of CCNA2 protein |
CTD |
PMID:21457722 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnd1 |
cyclin D1 |
increases expression decreases expression multiple interactions |
ISO |
baicalin results in increased expression of CCND1 mRNA baicalin results in decreased expression of CCND1 protein N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA] |
CTD |
PMID:19160421 PMID:21457722 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
EXP |
baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] |
CTD |
PMID:19474275 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein |
CTD |
PMID:18451504 PMID:26204831 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions increases expression |
ISO |
3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein] resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein] baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein |
CTD |
PMID:26204831 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] |
CTD |
PMID:25625231 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] |
CTD |
PMID:25625231 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Elk1 |
ETS transcription factor ELK1 |
multiple interactions |
ISO |
baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] |
CTD |
PMID:25625231 |
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NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:29031535 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Foxa2 |
forkhead box A2 |
decreases expression |
ISO |
baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein |
CTD |
PMID:32687838 |
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NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] |
CTD |
PMID:15645217 |
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NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP ISO |
baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein] baicalin inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein] |
CTD |
PMID:15645217 PMID:35088608 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Hes1 |
hes family bHLH transcription factor 1 |
increases expression multiple interactions |
ISO |
baicalin results in increased expression of HES1 mRNA N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA] |
CTD |
PMID:19160421 |
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NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hey1 |
hes-related family bHLH transcription factor with YRPW motif 1 |
increases expression multiple interactions |
ISO |
baicalin results in increased expression of HEY1 mRNA N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA] |
CTD |
PMID:19160421 |
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NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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G |
Hey2 |
hes-related family bHLH transcription factor with YRPW motif 2 |
multiple interactions increases expression |
ISO |
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] |
CTD |
PMID:19160421 |
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NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO EXP |
[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of HMOX1 protein]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein] baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein |
CTD |
PMID:16824337 PMID:18187930 PMID:38016618 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf1a |
HNF1 homeobox A |
multiple interactions decreases expression |
ISO |
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein] baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein |
CTD |
PMID:32687838 |
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NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression multiple interactions |
ISO |
baicalin results in decreased expression of HNF4A protein baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens] baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein |
CTD |
PMID:32687838 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein] |
CTD |
PMID:34414639 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]] baicalin inhibits the reaction [Rotenone results in increased expression of IL1B protein] |
CTD |
PMID:29031535 PMID:35088608 PMID:36446982 PMID:38016618 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
EXP ISO |
baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein] |
CTD |
PMID:22019745 PMID:29031535 PMID:34333357 PMID:35088608 PMID:38016618 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] |
CTD |
PMID:34414639 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Itga4 |
integrin subunit alpha 4 |
multiple interactions |
EXP |
baicalin inhibits the reaction [ITGA4 protein results in increased expression of KDR protein]; baicalin inhibits the reaction [ITGA4 protein results in increased expression of VEGFA protein] |
CTD |
PMID:36731809 |
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NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:35088608 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Kdr |
kinase insert domain receptor |
multiple interactions |
EXP |
baicalin inhibits the reaction [ITGA4 protein results in increased expression of KDR protein] |
CTD |
PMID:36731809 |
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NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein] |
CTD |
PMID:38016618 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:34414639 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34414639 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
decreases expression |
EXP |
baicalin results in decreased expression of MYD88 protein |
CTD |
PMID:22019745 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of NFE2L2 protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] |
CTD |
PMID:38016618 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
EXP |
baicalin results in increased expression of NFKBIA protein |
CTD |
PMID:22019745 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]] |
CTD |
PMID:29031535 PMID:38016618 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
EXP ISO |
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]] baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein] |
CTD |
PMID:18187930 PMID:22019745 PMID:24312512 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Notch1 |
notch receptor 1 |
increases activity increases expression |
ISO |
baicalin results in increased activity of NOTCH1 protein baicalin results in increased expression of NOTCH1 mRNA |
CTD |
PMID:19160421 |
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NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Baicalin increases expression of NR1H3 mRNA and protein in foam cells |
RGD |
PMID:27389392 |
RGD:401842390 |
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Pkm |
pyruvate kinase M1/2 |
increases activity |
ISO |
baicalin results in increased activity of PKM protein |
CTD |
PMID:25388478 |
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NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
EXP |
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] |
CTD |
PMID:24312512 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Prima1 |
proline rich membrane anchor 1 |
increases expression |
EXP |
baicalin results in increased expression of PRIMA1 mRNA |
CTD |
PMID:27019979 |
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NCBI chr 6:122,338,365...122,390,955
Ensembl chr 6:122,338,370...122,389,921
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
EXP |
baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein |
CTD |
PMID:22019745 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]] |
CTD |
PMID:38016618 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP ISO |
baicalin affects the localization of and results in decreased expression of RELA protein baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] |
CTD |
PMID:22019745 PMID:34333357 PMID:38016618 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Snca |
synuclein alpha |
multiple interactions |
ISO |
[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] |
CTD |
PMID:38016618 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:35088608 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Tek |
TEK receptor tyrosine kinase |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA] |
CTD |
PMID:34414639 |
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NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
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G |
Tfam |
transcription factor A, mitochondrial |
decreases expression multiple interactions |
ISO |
baicalin results in decreased expression of TFAM mRNA baicalin inhibits the reaction [Rotenone results in decreased expression of TFAM mRNA] |
CTD |
PMID:36446982 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] |
CTD |
PMID:19474275 PMID:34414639 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein] |
CTD |
PMID:38016618 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Tlr4 |
toll-like receptor 4 |
decreases expression multiple interactions |
EXP ISO |
baicalin results in decreased expression of TLR4 protein baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TLR4 protein] baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] |
CTD |
PMID:22019745 PMID:24312512 PMID:34333357 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression |
ISO EXP |
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein] |
CTD |
PMID:16824337 PMID:18187930 PMID:22019745 PMID:34333357 PMID:35088608 PMID:38016618 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
baicalin results in increased expression of TP53 protein |
CTD |
PMID:21457722 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Txnip |
thioredoxin interacting protein |
multiple interactions |
ISO |
baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] |
CTD |
PMID:29031535 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Usp27x |
ubiquitin specific peptidase 27, X-linked |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] |
CTD |
PMID:34414639 |
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NCBI chr X:15,123,620...15,126,855
Ensembl chr X:15,124,596...15,125,912
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
baicalin inhibits the reaction [ITGA4 protein results in increased expression of VEGFA protein] |
CTD |
PMID:36731809 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfc |
vascular endothelial growth factor C |
multiple interactions |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] |
CTD |
PMID:34414639 |
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NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
ISO |
baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] |
CTD |
PMID:34044073 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Cmas |
cytidine monophosphate N-acetylneuraminic acid synthetase |
affects abundance |
ISO |
CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid |
CTD |
PMID:27380425 |
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NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
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G |
Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of gluconic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of gluconic acid] |
CTD |
PMID:39172838 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ARNT2 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153
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G |
Atp6v1f |
ATPase H+ transporting V1 subunit F |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ATP6V1F mRNA |
CTD |
PMID:16556975 |
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NCBI chr 4:58,067,666...58,070,628
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
gluconic acid promotes the reaction [Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]] |
CTD |
PMID:27017951 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[gluconic acid co-treated with Zinc Sulfate] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] |
CTD |
PMID:27017951 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Cblb |
Cbl proto-oncogene B |
decreases expression |
EXP |
gluconic acid results in decreased expression of CBLB mRNA |
CTD |
PMID:16556975 |
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NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
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G |
Clcn3 |
chloride voltage-gated channel 3 |
increases response to substance |
ISO |
CLCN3 protein results in increased susceptibility to gluconic acid |
CTD |
PMID:12843258 |
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NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
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G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
increases expression |
EXP |
gluconic acid results in increased expression of CRHR1 mRNA |
CTD |
PMID:16556975 |
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NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of CSF1R mRNA |
CTD |
PMID:16556975 |
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NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Cyp4a8 |
cytochrome P450, family 4, subfamily a, polypeptide 8 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of CYP4A8 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
decreases expression |
EXP |
gluconic acid results in decreased expression of FYN mRNA |
CTD |
PMID:16556975 |
|
NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein] |
CTD |
PMID:30031400 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Grk2 |
G protein-coupled receptor kinase 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of GRK2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
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G |
Hcn4 |
hyperpolarization activated cyclic nucleotide-gated potassium channel 4 |
increases expression |
EXP |
gluconic acid results in increased expression of HCN4 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
EXP |
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA] |
CTD |
PMID:30031400 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hoxa1 |
homeobox A1 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of HOXA1 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Kcnc1 |
potassium voltage-gated channel subfamily C member 1 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of KCNC1 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
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G |
Kif3c |
kinesin family member 3C |
increases expression |
EXP |
gluconic acid results in increased expression of KIF3C mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 6:26,367,092...26,406,033
Ensembl chr 6:26,366,531...26,406,130
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G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
EXP |
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in decreased expression of LCAT mRNA] |
CTD |
PMID:30031400 |
|
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of LPL mRNA |
CTD |
PMID:16556975 |
|
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Mdh1 |
malate dehydrogenase 1 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of MDH1 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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G |
Mdh2 |
malate dehydrogenase 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of MDH2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
ISO |
gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT1A mRNA]] |
CTD |
PMID:27017951 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]] |
CTD |
PMID:27017951 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of NR1D2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions |
EXP |
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] affects the reaction [Dietary Fats results in increased expression of NR1H3 mRNA] |
CTD |
PMID:30031400 |
|
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Pak1 |
p21 (RAC1) activated kinase 1 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PAK1 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
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G |
Pgap2 |
post-GPI attachment to proteins 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PGAP2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 1:156,591,540...156,618,116
Ensembl chr 1:156,591,615...156,618,114
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G |
Prkar1a |
protein kinase cAMP-dependent type I regulatory subunit alpha |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKAR1A mRNA |
CTD |
PMID:16556975 |
|
NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041
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G |
Prkca |
protein kinase C, alpha |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKCA mRNA |
CTD |
PMID:16556975 |
|
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of gluconic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of gluconic acid] |
CTD |
PMID:39172838 |
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NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTGES mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 3:14,177,892...14,189,236
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G |
Ptpn2 |
protein tyrosine phosphatase, non-receptor type 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTPN2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627
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G |
Rara |
retinoic acid receptor, alpha |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RARA mRNA |
CTD |
PMID:16556975 |
|
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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G |
Rxrg |
retinoid X receptor gamma |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RXRG mRNA |
CTD |
PMID:16556975 |
|
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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G |
Sema6c |
semaphorin 6C |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SEMA6C mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 2:182,733,635...182,750,066
Ensembl chr 2:182,737,474...182,746,856
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G |
Sirpa |
signal-regulatory protein alpha |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SIRPA mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 3:116,819,730...116,858,099
Ensembl chr 3:116,819,726...116,858,098
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G |
Slc15a2 |
solute carrier family 15 member 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC15A2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225
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G |
Slc22a12 |
solute carrier family 22 member 12 |
multiple interactions |
ISO |
gluconic acid promotes the reaction [SLC22A12 protein affects the transport of Uric Acid] |
CTD |
PMID:14747372 |
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NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
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G |
Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions |
ISO |
gluconic acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] |
CTD |
PMID:12472777 |
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NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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G |
Slc22a8 |
solute carrier family 22 member 8 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC22A8 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
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G |
Slc32a1 |
solute carrier family 32 member 1 |
decreases expression |
EXP |
gluconic acid results in decreased expression of SLC32A1 mRNA |
CTD |
PMID:16556975 |
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NCBI chr 3:147,267,373...147,271,842
Ensembl chr 3:147,267,373...147,271,844
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G |
Slc6a8 |
solute carrier family 6 member 8 |
increases expression |
EXP |
gluconic acid results in increased expression of SLC6A8 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr X:151,384,675...151,393,979
Ensembl chr X:151,384,675...151,393,979
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
ISO |
[gluconic acid co-treated with Zinc Sulfate] promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA] |
CTD |
PMID:27017951 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
EXP |
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] |
CTD |
PMID:30031400 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Sstr3 |
somatostatin receptor 3 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SSTR3 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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G |
Tas2r106 |
taste receptor, type 2, member 106 |
decreases expression |
EXP |
gluconic acid results in decreased expression of TAS2R10 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 4:165,313,210...165,314,133
Ensembl chr 4:165,313,210...165,314,133
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G |
Ube2i |
ubiquitin-conjugating enzyme E2I |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of UBE2I mRNA |
CTD |
PMID:16556975 |
|
NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443 Ensembl chr10:69,701,618...69,702,443
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G |
Vamp2 |
vesicle-associated membrane protein 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of VAMP2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
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G |
Vax2 |
ventral anterior homeobox 2 |
multiple interactions |
EXP |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of VAX2 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 4:116,195,528...116,219,597
Ensembl chr 4:116,195,528...116,219,594
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G |
Vps52 |
VPS52 subunit of GARP complex |
increases expression |
EXP |
gluconic acid results in increased expression of VPS52 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr20:4,920,715...4,931,685
Ensembl chr20:4,860,843...4,931,665
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G |
Wee1 |
WEE1 G2 checkpoint kinase |
increases expression |
EXP |
gluconic acid results in increased expression of WEE1 mRNA |
CTD |
PMID:16556975 |
|
NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
glucuronolactone results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
increases abundance multiple interactions |
ISO |
IDH2 protein mutant form results in increased abundance of glyceric acid Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid] |
CTD |
PMID:27469509 |
|
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
EXP |
estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide] |
CTD |
PMID:9794924 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Kl |
Klotho |
multiple interactions increases hydrolysis |
ISO |
estriol 3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] KL protein results in increased hydrolysis of estriol 3-glucuronide |
CTD |
PMID:14701853 |
|
NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Kl |
Klotho |
increases hydrolysis multiple interactions |
ISO |
KL protein results in increased hydrolysis of estrone-3-glucuronide estrone-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] |
CTD |
PMID:14701853 |
|
NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Lepr |
leptin receptor |
affects abundance |
ISO |
LEPR affects the abundance of galactaric acid |
CTD |
PMID:20567778 |
|
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Ago2 |
argonaute RISC catalytic component 2 |
multiple interactions |
ISO |
Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein] |
CTD |
PMID:24792773 |
|
NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein] |
CTD |
PMID:25478867 |
|
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein] |
CTD |
PMID:25478867 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein] |
CTD |
PMID:25478867 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
multiple interactions |
ISO |
Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein] |
CTD |
PMID:24792773 |
|
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein] |
CTD |
PMID:25478867 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein] |
CTD |
PMID:25478867 |
|
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; [Plant Extracts co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein] |
CTD |
PMID:20103723 PMID:25478867 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CDKN2A promoter] |
CTD |
PMID:24792773 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:20103723 |
|
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Dicer1 |
dicer 1 ribonuclease III |
multiple interactions |
ISO |
Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein] |
CTD |
PMID:24792773 |
|
NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein] |
CTD |
PMID:24792773 |
|
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA] |
CTD |
PMID:20103723 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Hdac1 |
histone deacetylase 1 |
multiple interactions |
ISO |
Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein] |
CTD |
PMID:24792773 |
|
NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] |
CTD |
PMID:20103723 |
|
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA] |
CTD |
PMID:23835587 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein] |
CTD |
PMID:23835587 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Mir3545 |
microRNA 3545 |
multiple interactions |
ISO |
Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of MIR203 promoter] |
CTD |
PMID:24792773 |
|
NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions |
ISO |
Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein] |
CTD |
PMID:24792773 |
|
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
[Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein] |
CTD |
PMID:23835587 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] |
CTD |
PMID:20103723 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[Resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA] |
CTD |
PMID:23835587 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein] |
CTD |
PMID:25478867 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
increases reduction |
ISO EXP |
AKR1A1 protein results in increased reduction of Glucuronic Acid |
CTD |
PMID:10510318 PMID:29763686 |
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NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid] |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions decreases activity |
ISO |
Glycyrrhizic Acid inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Glycyrrhizic Acid results in decreased activity of ABCB11 protein |
CTD |
PMID:24014644 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
multiple interactions |
ISO |
Glycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA] |
CTD |
PMID:28549656 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ACAT2 mRNA] |
CTD |
PMID:28549656 |
|
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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G |
Ache |
acetylcholinesterase |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of ACHE protein] |
CTD |
PMID:31150628 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acta2 |
actin alpha 2, smooth muscle |
decreases expression multiple interactions |
ISO EXP |
Glycyrrhizic Acid results in decreased expression of ACTA2 protein Glycyrrhizic Acid inhibits the reaction [Sodium Nitrite results in increased expression of ACTA2 protein] |
CTD |
PMID:33030083 PMID:33522686 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:32525084 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
ISO |
ALB protein binds to and affects the transport of Glycyrrhizic Acid |
CTD |
PMID:8831264 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aqp2 |
aquaporin 2 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Gentamicins results in decreased expression of AQP2 protein] |
CTD |
PMID:12969435 |
|
NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
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G |
Aqp5 |
aquaporin 5 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Histamine results in decreased expression of AQP5 protein] |
CTD |
PMID:29452068 |
|
NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
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G |
Ar |
androgen receptor |
multiple interactions affects localization |
ISO |
Glycyrrhizic Acid binds to and results in increased activity of AR protein Glycyrrhizic Acid affects the localization of AR protein |
CTD |
PMID:28478275 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of BAD mRNA |
CTD |
PMID:35844403 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of BAX mRNA |
CTD |
PMID:35844403 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO |
Glycyrrhizic Acid results in decreased expression of BCL2 mRNA [Glycyrrhizic Acid co-treated with Cisplatin] results in decreased expression of BCL2 mRNA |
CTD |
PMID:35844403 PMID:37659683 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of BDNF protein] |
CTD |
PMID:31150628 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Casp2 |
caspase 2 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP2 protein] |
CTD |
PMID:22051199 |
|
NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity |
EXP ISO |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP3 protein]; Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of CASP3 protein] [Glycyrrhizic Acid co-treated with Cisplatin] results in increased expression of CASP3 mRNA Glycyrrhizic Acid results in increased activity of CASP3 protein |
CTD |
PMID:22051199 PMID:31150628 PMID:35844403 PMID:37659683 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp6 |
caspase 6 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP6 protein] |
CTD |
PMID:22051199 |
|
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp8 |
caspase 8 |
multiple interactions increases activity |
EXP ISO |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP8 protein] [Glycyrrhizic Acid co-treated with Cisplatin] results in increased expression of CASP8 mRNA Glycyrrhizic Acid results in increased activity of CASP8 protein |
CTD |
PMID:22051199 PMID:35844403 PMID:37659683 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases activity |
EXP ISO |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP9 protein] [Glycyrrhizic Acid co-treated with Cisplatin] results in increased expression of CASP9 mRNA Glycyrrhizic Acid results in increased activity of CASP9 protein |
CTD |
PMID:22051199 PMID:35844403 PMID:37659683 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Cyclosporine results in increased expression of CCL2 mRNA] |
CTD |
PMID:27585667 |
|
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccnd1 |
cyclin D1 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of CCND1 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd68 |
Cd68 molecule |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Sodium Nitrite results in increased expression of CD68 protein] |
CTD |
PMID:33030083 |
|
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cdh1 |
cadherin 1 |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of CDH1 protein |
CTD |
PMID:33522686 |
|
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of CDK4 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of CDKN1A mRNA |
CTD |
PMID:35844403 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPB mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPD mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Histamine results in decreased phosphorylation of CREB1 protein] |
CTD |
PMID:29452068 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
EXP |
Glycyrrhizic Acid results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:10474021 PMID:11798659 |
|
NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases expression |
ISO |
NR1I2 protein affects the reaction [Glycyrrhizic Acid results in increased expression of CYP3A4 mRNA] Glycyrrhizic Acid results in increased expression of CYP3A4 mRNA; Glycyrrhizic Acid results in increased expression of CYP3A4 protein |
CTD |
PMID:22982774 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression multiple interactions |
ISO |
Glycyrrhizic Acid results in decreased expression of CYP7A1 mRNA Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] |
CTD |
PMID:22982774 PMID:28549656 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Ephx2 |
epoxide hydrolase 2 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in decreased activity of EPHX2 protein] |
CTD |
PMID:22051199 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP ISO |
Glycyrrhizic Acid inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with BCG Vaccine] results in increased activity of GPT protein] Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of GPT protein]; Glycyrrhizic Acid inhibits the reaction [diosbulbin B results in increased activity of GPT protein] |
CTD |
PMID:19196740 PMID:28549656 PMID:37794747 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Hes1 |
hes family bHLH transcription factor 1 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of HES1 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hmgb1 |
high mobility group box 1 |
decreases secretion multiple interactions decreases activity |
ISO EXP |
Glycyrrhizic Acid results in decreased secretion of HMGB1 protein Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of HMGB1 protein] Glycyrrhizic Acid results in decreased activity of HMGB1 protein |
CTD |
PMID:27585667 PMID:27689324 PMID:27783111 PMID:32525084 |
|
NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; Glycyrrhizic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein] |
CTD |
PMID:17917259 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases expression |
EXP |
Glycyrrhizic Acid results in decreased expression of HSD11B2 mRNA |
CTD |
PMID:10474021 PMID:11798659 |
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NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Ifng |
interferon gamma |
affects expression |
ISO |
Glycyrrhizic Acid affects the expression of IFNG mRNA |
CTD |
PMID:16945185 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12A mRNA |
CTD |
PMID:11412311 |
|
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B protein |
CTD |
PMID:11412311 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Sodium Nitrite results in increased expression of IL1B protein] |
CTD |
PMID:33030083 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO EXP |
Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] Glycyrrhizic Acid inhibits the reaction [Histamine results in increased expression of IL6 mRNA]; Glycyrrhizic Acid inhibits the reaction [Histamine results in increased secretion of IL6 protein] Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of IL6 mRNA]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of IL6 protein] |
CTD |
PMID:21644799 PMID:26524701 PMID:29452068 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPB mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPD mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of LPL mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SCD1 mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SLC2A4 mRNA]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein]; Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34302803 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Jag1 |
jagged canonical Notch ligand 1 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of JAG1 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of LPL mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
EXP |
[Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:32525084 |
|
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:34302803 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:34302803 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Picryl Chloride results in increased secretion of MMP2 protein] [Glycyrrhizic Acid co-treated with Cisplatin] results in decreased expression of MMP2 mRNA |
CTD |
PMID:16945185 PMID:37659683 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[Glycyrrhizic Acid co-treated with Cisplatin] results in decreased expression of MMP9 mRNA |
CTD |
PMID:37659683 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [diosbulbin B results in increased activity of MPO protein] |
CTD |
PMID:37794747 |
|
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MTOR protein] |
CTD |
PMID:32525084 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MTTP mRNA] |
CTD |
PMID:28549656 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Histamine results in increased expression of MUC5AC mRNA]; Glycyrrhizic Acid inhibits the reaction [Histamine results in increased secretion of MUC5AC protein] |
CTD |
PMID:29452068 |
|
NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased activity of [NFKB1 protein binds to RELA protein] |
CTD |
PMID:11412311 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Histamine results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:29452068 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] |
CTD |
PMID:17917259 PMID:21644799 PMID:23373965 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Notch1 |
notch receptor 1 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of NOTCH1 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of NPC1L1 mRNA] |
CTD |
PMID:28549656 |
|
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of NR0B2 mRNA |
CTD |
PMID:22982774 |
|
NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity multiple interactions |
ISO |
Glycyrrhizic Acid results in increased activity of NR1I2 protein NR1I2 protein affects the reaction [Glycyrrhizic Acid results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:22982774 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
decreases activity |
ISO |
Glycyrrhizic Acid results in decreased activity of PIK3CD protein |
CTD |
PMID:21644799 |
|
NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
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G |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
decreases activity |
ISO |
Glycyrrhizic Acid results in decreased activity of PIK3CG protein |
CTD |
PMID:21644799 |
|
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA] |
CTD |
PMID:34302803 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] |
CTD |
PMID:17917259 PMID:21644799 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rad21 |
RAD21 cohesin complex component |
decreases binding |
ISO |
Glycyrrhizinic acid decreases binding of RAD21 protein to SMC3 protein in lymphoma cells |
RGD |
PMID:21880767 |
RGD:243065267 |
NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased activity of [NFKB1 protein binds to RELA protein] Glycyrrhizic Acid inhibits the reaction [Histamine results in increased phosphorylation of RELA protein] Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene affects the localization of RELA protein]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased phosphorylation of RELA protein] |
CTD |
PMID:11412311 PMID:22051199 PMID:26524701 PMID:29452068 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Ren |
renin |
decreases activity |
ISO |
Glycyrrhizic Acid results in decreased activity of REN protein |
CTD |
PMID:20460744 |
|
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SCD1 mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of SIRT1 protein] |
CTD |
PMID:25162824 |
|
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SLC2A4 mRNA] |
CTD |
PMID:34302803 |
|
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc51b |
SLC51 subunit beta |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLC51B mRNA] |
CTD |
PMID:28549656 |
|
NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
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G |
Slco1a4 |
solute carrier organic anion transporter family, member 1a4 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLCO1A4 mRNA] |
CTD |
PMID:28549656 |
|
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
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G |
Smad4 |
SMAD family member 4 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of SMAD4 protein |
CTD |
PMID:33522686 |
|
NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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G |
Smad7 |
SMAD family member 7 |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of SMAD7 protein |
CTD |
PMID:33522686 |
|
NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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G |
Sod1 |
superoxide dismutase 1 |
increases activity |
ISO |
Glycyrrhizic Acid results in increased activity of SOD1 protein |
CTD |
PMID:37659683 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of SOD2 protein] |
CTD |
PMID:25162824 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
EXP |
Glycyrrhizic Acid affects the reaction [Doxorubicin results in increased expression of SQSTM1 protein] |
CTD |
PMID:32525084 |
|
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Glycyrrhizic Acid inhibits the reaction [Glucose results in increased expression of TGFB1 protein]; Glycyrrhizic Acid inhibits the reaction [Sodium Nitrite results in increased expression of TGFB1 protein] |
CTD |
PMID:25162824 PMID:33030083 |
|
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of TGFBR1 protein |
CTD |
PMID:33522686 |
|
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
decreases expression |
ISO |
Glycyrrhizic Acid results in decreased expression of TGFBR2 protein |
CTD |
PMID:33522686 |
|
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of TJP1 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein] |
CTD |
PMID:27689324 PMID:27783111 |
|
NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tjp2 |
tight junction protein 2 |
multiple interactions |
ISO |
Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of TJP2 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein] |
CTD |
PMID:27689324 PMID:27783111 |
|
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO EXP |
Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of TNF mRNA]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; Glycyrrhizic Acid inhibits the reaction [Sodium Nitrite results in increased expression of TNF protein] |
CTD |
PMID:17917259 PMID:21644799 PMID:26524701 PMID:33030083 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
increases expression |
ISO |
Glycyrrhizic Acid results in increased expression of TP53 mRNA |
CTD |
PMID:35844403 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
A2m |
alpha-2-macroglobulin |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Aars1 |
alanyl-tRNA synthetase 1 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of AARS1 mRNA |
CTD |
PMID:19197388 |
|
NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [T0901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA] |
CTD |
PMID:17639512 PMID:25932594 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO EXP |
Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA] [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA] |
CTD |
PMID:22914566 PMID:31739238 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA] |
CTD |
PMID:22914566 PMID:34480604 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
ISO EXP |
Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein] |
CTD |
PMID:19326901 PMID:22914566 PMID:31005848 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Acan |
aggrecan |
multiple interactions |
ISO |
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]] |
CTD |
PMID:26526931 |
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein] |
CTD |
PMID:28544013 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ACE2 mRNA |
CTD |
PMID:17639512 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Ache |
acetylcholinesterase |
decreases activity multiple interactions increases activity |
ISO EXP |
Ascorbic Acid results in decreased activity of ACHE protein [Dexamethasone co-treated with Ascorbic Acid] results in increased expression of ACHE mRNA; [Dexamethasone co-treated with Ascorbic Acid] results in increased expression of and results in increased activity of ACHE protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased activity of ACHE protein] Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein] Ascorbic Acid results in increased activity of ACHE protein [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein] |
CTD |
PMID:11814146 PMID:16248992 PMID:16822217 PMID:19703495 PMID:20663516 PMID:23619517 PMID:26163454 PMID:27019979 PMID:35187746 More...
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
decreases expression |
EXP |
Ascorbic Acid results in decreased expression of ACSL4 mRNA |
CTD |
PMID:15372504 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP ISO |
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of ACTA2 protein [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Mercaptoethanol co-treated with Ascorbic Acid] results in increased expression of ACTA2 protein; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA] |
CTD |
PMID:7593635 PMID:17053324 PMID:18607632 PMID:27381660 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actn2 |
actinin alpha 2 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA |
CTD |
PMID:34480604 |
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NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
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G |
Adcy6 |
adenylate cyclase 6 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of ADCY6 mRNA |
CTD |
PMID:17303424 |
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NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754
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G |
Adgrl1 |
adhesion G protein-coupled receptor L1 |
decreases expression |
EXP |
Ascorbic Acid results in decreased expression of ADGRL1 mRNA |
CTD |
PMID:15372504 |
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NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
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G |
Afp |
alpha-fetoprotein |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA |
CTD |
PMID:34480604 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Ago2 |
argonaute RISC catalytic component 2 |
decreases expression |
EXP |
Ascorbic Acid results in decreased expression of AGO2 mRNA |
CTD |
PMID:15372504 |
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NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP ISO |
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein] [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]; Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]] |
CTD |
PMID:20881940 PMID:26111765 PMID:31144504 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ak4 |
adenylate kinase 4 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of AK4 mRNA |
CTD |
PMID:15305145 |
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NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
decreases abundance multiple interactions |
ISO |
AKR1A1 gene mutant form results in decreased abundance of Ascorbic Acid [AKR1A1 gene mutant form results in increased susceptibility to Diethylnitrosamine] which results in decreased abundance of Ascorbic Acid; AKR1A1 gene mutant form promotes the reaction [Diethylnitrosamine results in decreased abundance of Ascorbic Acid] |
CTD |
PMID:32805337 |
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NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
increases reduction |
ISO |
Ascorbic Acid results in increased reduction of AKR1B1 protein modified form |
CTD |
PMID:19061876 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of AKR1B10 mRNA |
CTD |
PMID:26198647 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of AKR1C2 mRNA |
CTD |
PMID:26198647 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:21262251 PMID:21911000 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
affects expression |
ISO |
Ascorbic Acid affects the expression of AKT2 mRNA |
CTD |
PMID:30597948 |
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NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alas1 |
5'-aminolevulinate synthase 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein] |
CTD |
PMID:24523661 |
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NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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G |
Alb |
albumin |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA |
CTD |
PMID:34480604 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
ISO |
ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin] |
CTD |
PMID:23194305 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldoa |
aldolase, fructose-bisphosphate A |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA |
CTD |
PMID:34480604 |
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NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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G |
Alpi |
alkaline phosphatase, intestinal |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ALPI mRNA |
CTD |
PMID:17639512 |
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NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA] [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA] Ascorbic Acid results in increased expression of ALPL mRNA |
CTD |
PMID:26424790 PMID:26492236 PMID:28105418 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Amhr2 |
anti-Mullerian hormone receptor type 2 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258
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G |
Anpep |
alanyl aminopeptidase, membrane |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA |
CTD |
PMID:17639512 |
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NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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G |
Anxa1 |
annexin A1 |
multiple interactions increases expression |
ISO EXP |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA Ascorbic Acid results in increased expression of ANXA1 mRNA |
CTD |
PMID:15372504 PMID:17639512 PMID:34480604 |
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NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa5 |
annexin A5 |
multiple interactions increases expression |
ISO EXP |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA Ascorbic Acid results in increased expression of ANXA5 mRNA Ascorbic Acid results in increased expression of ANXA5 protein |
CTD |
PMID:15372504 PMID:17917374 PMID:19224539 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Apoa1 |
apolipoprotein A1 |
decreases expression multiple interactions decreases activity |
ISO EXP |
Ascorbic Acid results in decreased expression of APOA1 mRNA; Ascorbic Acid results in decreased expression of APOA1 protein [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA Ascorbic Acid results in decreased activity of APOA1 promoter |
CTD |
PMID:16423621 PMID:34480604 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apob |
apolipoprotein B |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA; Ascorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Ascorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] |
CTD |
PMID:17475462 PMID:17639512 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
increases expression |
EXP |
Ascorbic Acid results in increased expression of APOE mRNA |
CTD |
PMID:15372504 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Apom |
apolipoprotein M |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNA |
CTD |
PMID:17639512 |
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NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550
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G |
App |
amyloid beta precursor protein |
multiple interactions decreases abundance increases oxidation |
EXP ISO |
Ascorbic Acid inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species]; resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Ascorbic Acid] APP protein modified form results in increased oxidation of Ascorbic Acid [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines; [APP protein modified form binds to Copper] which results in increased oxidation of Ascorbic Acid; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; APP protein inhibits the reaction [Copper results in increased oxidation of Ascorbic Acid]; APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]; Copper promotes the reaction [APP protein modified form results in increased oxidation of Ascorbic Acid]; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Penicillamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide] |
CTD |
PMID:15030205 PMID:17964426 PMID:24276282 PMID:25654502 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of AQP3 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
increases expression |
ISO |
Ascorbic Acid results in increased expression of ARHGDIA mRNA |
CTD |
PMID:22139585 |
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NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
multiple interactions increases expression |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of ARHGDIB mRNA Ascorbic Acid results in increased expression of ARHGDIB protein |
CTD |
PMID:17639512 PMID:22139585 |
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NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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G |
Arpc5 |
actin related protein 2/3 complex, subunit 5 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of ARPC5 mRNA; Ascorbic Acid results in increased expression of ARPC5 protein |
CTD |
PMID:22139585 |
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NCBI chr13:64,904,504...64,913,413
Ensembl chr13:64,887,136...64,913,410
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G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of ASNS mRNA |
CTD |
PMID:19197388 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Atad2 |
ATPase family, AAA domain containing 2 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of ATAD2 mRNA |
CTD |
PMID:26424790 |
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NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
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G |
Atad2b |
ATPase family, AAA domain containing 2B |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ATAD2B mRNA |
CTD |
PMID:26424790 |
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NCBI chr 6:27,914,546...28,070,103
Ensembl chr 6:27,912,862...28,067,047
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of ATF3 mRNA |
CTD |
PMID:17639512 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form] |
CTD |
PMID:17917374 PMID:25977998 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp5f1b |
ATP synthase F1 subunit beta |
increases expression |
ISO |
Ascorbic Acid results in increased expression of ATP5F1B protein |
CTD |
PMID:22139585 |
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NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
increases expression |
ISO |
Ascorbic Acid results in increased expression of ATP6V1A mRNA |
CTD |
PMID:22139585 |
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NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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G |
Aurkb |
aurora kinase B |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of AURKB mRNA |
CTD |
PMID:17639512 |
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NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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G |
Auts2 |
activator of transcription and developmental regulator AUTS2 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of AUTS2 mRNA |
CTD |
PMID:25555879 |
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NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416
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G |
B2m |
beta-2 microglobulin |
increases expression |
EXP |
Ascorbic Acid results in increased expression of B2M mRNA |
CTD |
PMID:15372504 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
Bach1 |
BTB domain and CNC homolog 1 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased expression of BACH1 protein] |
CTD |
PMID:28285367 |
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NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
EXP ISO |
Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein] [juglone co-treated with Ascorbic Acid] results in increased expression of BAD protein |
CTD |
PMID:21262251 PMID:29992683 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein |
CTD |
PMID:24126434 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO EXP |
[Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased expression of BAX protein; [juglone co-treated with Ascorbic Acid] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX protein] Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of BAX mRNA] Ascorbic Acid inhibits the reaction [Humic Substances results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein] |
CTD |
PMID:17166419 PMID:17959157 PMID:18683188 PMID:18758938 PMID:21262251 PMID:22245848 PMID:24126434 PMID:29992683 PMID:32632975 PMID:38160894 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] |
CTD |
PMID:20530418 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bche |
butyrylcholinesterase |
multiple interactions |
ISO |
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] |
CTD |
PMID:20663516 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions increases abundance |
ISO EXP |
Ascorbic Acid results in decreased expression of BCL2 mRNA Ascorbic Acid inhibits the reaction [glycidamide results in decreased expression of BCL2 mRNA] [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 protein] [alpha-Tocopherol co-treated with Ascorbic Acid] inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Humic Substances results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ascorbic Acid promotes the reaction [lead acetate results in increased expression of BCL2 protein] BCL2 protein results in increased abundance of Ascorbic Acid |
CTD |
PMID:15449323 PMID:17166419 PMID:17959157 PMID:18683188 PMID:18758938 PMID:21262251 PMID:21919647 PMID:22245848 PMID:24126434 PMID:27381660 PMID:29297235 PMID:32632975 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] |
CTD |
PMID:18758938 PMID:21262251 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bcl2l14 |
Bcl2-like 14 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of BCL2L14 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
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G |
Bcl2l2 |
Bcl2-like 2 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA |
CTD |
PMID:17917374 |
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NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
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G |
Bco1 |
beta-carotene oxygenase 1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] |
CTD |
PMID:9526112 |
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NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
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G |
Bdnf |
brain-derived neurotrophic factor |
increases expression multiple interactions |
ISO |
Ascorbic Acid results in increased expression of BDNF mRNA [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FOXM1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of FZD10 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of GLI1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HES3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of HOXB1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of INHBE mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of LEF1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of TERT mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GABRA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GFAP mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIA2 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN1 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of GRIN2B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of MAP2 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of RBFOX3 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of S100B protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SCN2A mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A6 mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SLC17A7 protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN mRNA; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of SYN protein; [BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of TUBB3 protein |
CTD |
PMID:15305145 PMID:33713149 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions affects binding |
ISO EXP |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Copper] affects the cleavage of BGLAP3 protein; [Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BGLAP mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] BGLAP3 protein binds to Ascorbic Acid 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA] [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]] |
CTD |
PMID:11396734 PMID:12510807 PMID:17692823 PMID:25932594 PMID:26492236 PMID:27028516 PMID:31935364 PMID:32473317 More...
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[juglone co-treated with Ascorbic Acid] affects the expression of BID protein |
CTD |
PMID:29992683 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of BIRC3 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of BIRC5 mRNA |
CTD |
PMID:21919647 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Bmp1 |
bone morphogenetic protein 1 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNA |
CTD |
PMID:15994055 |
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NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]] [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein] |
CTD |
PMID:15994055 PMID:26492236 PMID:27387537 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp3 |
bone morphogenetic protein 3 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP3 mRNA |
CTD |
PMID:15994055 |
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NCBI chr14:10,712,489...10,737,153
Ensembl chr14:10,712,489...10,737,153
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G |
Bmp4 |
bone morphogenetic protein 4 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GSTO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GUCY1A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAND2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HAVCR1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HMGCS2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXB3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HOXD8 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of HSD3B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGFBP7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IGHV3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of IL1R1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ISL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of KRT6A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LEF1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of LUM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MLIP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MMP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MPZL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of MYL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NQO1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of NR2F2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PDE1A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of PLN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RBM20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of RRAD mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCARB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SCN2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SEMA3C mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SERPINA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SLCO2B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of SQSTM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TBX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TF mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TFAP2A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TM4SF4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TTR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of TXNRD1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of UGT2A3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VCAM1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VGLL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of VTN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ZFAND2A mRNA |
CTD |
PMID:34480604 |
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NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp5 |
bone morphogenetic protein 5 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP7 mRNA |
CTD |
PMID:15994055 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Bmpr1a |
bone morphogenetic protein receptor type 1A |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]] |
CTD |
PMID:27387537 |
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NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
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G |
Bmpr1b |
bone morphogenetic protein receptor type 1B |
increases expression |
ISO |
Ascorbic Acid results in increased expression of BMPR1B mRNA |
CTD |
PMID:15305145 |
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NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368
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G |
Bub1 |
BUB1 mitotic checkpoint serine/threonine kinase |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
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G |
C3 |
complement C3 |
increases expression |
EXP |
Ascorbic Acid results in increased expression of C3 mRNA |
CTD |
PMID:15372504 |
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NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C5 |
complement C5 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Ascorbic Acid inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] |
CTD |
PMID:10777245 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
C8h11orf54 |
similar to human chromosome 11 open reading frame 54 |
decreases expression multiple interactions |
ISO |
Ascorbic Acid results in decreased expression of C11ORF54 mRNA [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of C11ORF54 mRNA |
CTD |
PMID:25555879 |
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NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
decreases activity multiple interactions |
ISO |
Ascorbic Acid results in decreased activity of CACNA1H protein Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H protein] |
CTD |
PMID:34286406 |
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NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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G |
Calb2 |
calbindin 2 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CALB2 protein] |
CTD |
PMID:31708536 |
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NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
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G |
Car2 |
carbonic anhydrase 2 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of CAR2 mRNA |
CTD |
PMID:15730627 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Car9 |
carbonic anhydrase 9 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein] |
CTD |
PMID:16288478 |
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NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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G |
Casp2 |
caspase 2 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] |
CTD |
PMID:15158148 |
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NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression decreases activity |
ISO EXP |
[Arsenic Trioxide results in increased susceptibility to Ascorbic Acid] which results in increased cleavage of CASP3 protein; [Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA]; [juglone co-treated with Ascorbic Acid] results in decreased expression of CASP3 protein; Ascorbic Acid inhibits the reaction [[chromium hexavalent ion co-treated with Antimycin A] results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[chromium hexavalent ion co-treated with Rotenone] results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Antimycin A results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [hydroxyethyl methacrylate results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Rotenone results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [triethylene glycol dimethacrylate results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein] Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of CASP3 mRNA] Ascorbic Acid results in increased expression of CASP3 mRNA [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein] Ascorbic Acid results in decreased activity of CASP3 protein |
CTD |
PMID:12750841 PMID:15158148 PMID:16124896 PMID:16407847 PMID:16867262 PMID:16973328 PMID:17166419 PMID:17301063 PMID:17618090 PMID:17879260 PMID:18758938 PMID:20356860 PMID:21262251 PMID:21873648 PMID:22245848 PMID:22678527 PMID:23711929 PMID:24295472 PMID:24488945 PMID:24732427 PMID:29992683 PMID:30597948 PMID:31739238 PMID:32632975 PMID:33248029 PMID:33592258 PMID:35187746 PMID:38160894 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA] |
CTD |
PMID:18544905 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] |
CTD |
PMID:15158148 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein] |
CTD |
PMID:17301063 PMID:17879260 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions increases expression |
EXP ISO |
[Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA Ascorbic Acid results in increased expression of CASP8 mRNA Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein] |
CTD |
PMID:18544905 PMID:20400526 PMID:23711929 PMID:30597948 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions |
EXP ISO |
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein] Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein] |
CTD |
PMID:15158148 PMID:16973328 PMID:23711929 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cast |
calpastatin |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CAST mRNA |
CTD |
PMID:15372504 |
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NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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G |
Cat |
catalase |
affects expression increases expression increases activity decreases activity multiple interactions decreases response to substance |
ISO EXP |
Ascorbic Acid affects the expression of CAT protein Ascorbic Acid results in increased expression of CAT mRNA Ascorbic Acid results in increased activity of CAT protein Ascorbic Acid results in decreased activity of CAT protein [[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Lead] results in increased expression of CAT protein; [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased activity of CAT protein]; [Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ascorbic Acid inhibits the reaction [abamectin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [barium chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Food Additives affects the activity of CAT protein]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Sodium Benzoate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein] [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; [juglone co-treated with Ascorbic Acid] results in decreased activity of CAT protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [hydroxyethyl methacrylate results in increased degradation of CAT mRNA]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [triethylene glycol dimethacrylate results in increased degradation of CAT mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; CAT protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ascorbic Acid]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid] Ascorbic Acid results in increased expression of CAT protein [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]; [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]] CAT protein results in decreased susceptibility to Ascorbic Acid |
CTD |
PMID:10772068 PMID:12540038 PMID:12767684 PMID:14698046 PMID:15104111 PMID:16248992 PMID:16298753 PMID:16758767 PMID:17512118 PMID:17822687 PMID:18073202 PMID:18096215 PMID:18548748 PMID:18655177 PMID:18715643 PMID:18726076 PMID:19298665 PMID:19391111 PMID:19429265 PMID:20028703 PMID:20077558 PMID:20122981 PMID:20171736 PMID:20535553 PMID:20876158 PMID:21310208 PMID:21689642 PMID:22008531 PMID:22056337 PMID:22207723 PMID:23194016 PMID:23470461 PMID:23619517 PMID:23692848 PMID:24295472 PMID:24488945 PMID:25721553 PMID:27941167 PMID:29572072 PMID:29992683 PMID:30676168 PMID:31005848 PMID:31022331 PMID:31576639 PMID:31610155 PMID:31739238 PMID:32913121 PMID:33248029 PMID:34089294 PMID:35187746 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein] |
CTD |
PMID:35349355 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cbs |
cystathionine beta synthase |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of CBS mRNA |
CTD |
PMID:19197388 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
affects expression decreases expression |
ISO |
Ascorbic Acid affects the expression of CCL2 mRNA; Ascorbic Acid deficiency affects the expression of CCL2 mRNA Ascorbic Acid results in decreased expression of CCL2 mRNA |
CTD |
PMID:19932582 PMID:21796779 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl21 |
C-C motif chemokine ligand 21 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA |
CTD |
PMID:17917374 |
|
NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
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|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA |
CTD |
PMID:17917374 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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|
G |
Ccna1 |
cyclin A1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNA1 protein] |
CTD |
PMID:21621607 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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|
G |
Ccnb1 |
cyclin B1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein] |
CTD |
PMID:21621607 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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|
G |
Ccnc |
cyclin C |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA |
CTD |
PMID:17917374 |
|
NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
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|
G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression |
ISO EXP |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA; Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of CCND1 mRNA] Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND1 protein] Ascorbic Acid results in decreased expression of CCND1 mRNA |
CTD |
PMID:17917374 PMID:21621607 PMID:21919647 PMID:30140404 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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|
G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO EXP |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CCND2 mRNA Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND2 protein] |
CTD |
PMID:17639512 PMID:21621607 |
|
NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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|
G |
Ccnd3 |
cyclin D3 |
multiple interactions |
EXP ISO |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein] Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein] |
CTD |
PMID:21621607 PMID:29992683 |
|
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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|
G |
Ccne2 |
cyclin E2 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNE2 protein] |
CTD |
PMID:21621607 |
|
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
|
|
G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO EXP |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA |
CTD |
PMID:17917374 PMID:18544905 |
|
NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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|
G |
Cd24 |
CD24 molecule |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA |
CTD |
PMID:17639512 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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|
G |
Cd34 |
CD34 molecule |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD34 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832
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|
G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD40 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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|
G |
Cd44 |
CD44 molecule |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein] |
CTD |
PMID:23692848 |
|
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd48 |
Cd48 molecule |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CD48 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
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|
G |
Cd69 |
Cd69 molecule |
decreases expression |
ISO |
Ascorbic Acid deficiency results in decreased expression of CD69 protein |
CTD |
PMID:22306178 |
|
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd82 |
Cd82 molecule |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CD82 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
|
|
G |
Cdc20 |
cell division cycle 20 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc6 |
cell division cycle 6 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CDC6 mRNA |
CTD |
PMID:17639512 |
|
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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G |
Cdh10 |
cadherin 10 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995
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G |
Cdh13 |
cadherin 13 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of CDH13 mRNA |
CTD |
PMID:15305145 |
|
NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
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G |
Cdh2 |
cadherin 2 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein] |
CTD |
PMID:29940330 |
|
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh22 |
cadherin 22 |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CDH22 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 3:153,845,563...153,970,630
Ensembl chr 3:153,845,787...153,970,588
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK1 protein] |
CTD |
PMID:21621607 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein] |
CTD |
PMID:21621607 |
|
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
EXP ISO |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein] [juglone co-treated with Ascorbic Acid] results in decreased expression of CDK4 protein |
CTD |
PMID:21621607 PMID:29992683 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk6 |
cyclin-dependent kinase 6 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK6 protein] |
CTD |
PMID:21621607 |
|
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO EXP |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA Ascorbic Acid results in increased expression of CDKN1A mRNA [INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] |
CTD |
PMID:17917374 PMID:20067818 PMID:20400526 PMID:20530418 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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|
G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA |
CTD |
PMID:18544905 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein] |
CTD |
PMID:21621607 |
|
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
|
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G |
Ceacam6 |
CEA cell adhesion molecule 6 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of CEBPA protein [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA |
CTD |
PMID:14505802 PMID:25932594 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CEBPB mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cfb |
complement factor B |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of CFB mRNA |
CTD |
PMID:17639512 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions increases activity |
ISO |
[Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein; Ascorbic Acid inhibits the reaction [Vehicle Emissions results in decreased activity of CFTR protein]; Ascorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides] Ascorbic Acid results in increased activity of CFTR protein |
CTD |
PMID:14993613 PMID:32374624 PMID:34601066 |
|
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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G |
Chaf1b |
chromatin assembly factor 1 subunit B |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of CHAF1B mRNA |
CTD |
PMID:26424790 |
|
NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070
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G |
Chat |
choline O-acetyltransferase |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] |
CTD |
PMID:25891525 |
|
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
EXP ISO |
Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA] Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of CHEK2 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] |
CTD |
PMID:18544905 PMID:25977998 PMID:31388677 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
|
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G |
Cidec |
cell death-inducing DFFA-like effector c |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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G |
Cit |
citron rho-interacting serine/threonine kinase |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CIT mRNA |
CTD |
PMID:17639512 |
|
NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
|
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G |
Cited1 |
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] |
CTD |
PMID:28189605 |
|
NCBI chr X:67,350,376...67,355,072
Ensembl chr X:67,350,373...67,355,162
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G |
Clu |
clusterin |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CLU mRNA |
CTD |
PMID:15372504 |
|
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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G |
Cmip |
c-Maf-inducing protein |
increases expression multiple interactions |
ISO |
Ascorbic Acid results in increased expression of CMIP mRNA [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CMIP mRNA |
CTD |
PMID:25555879 |
|
NCBI chr19:45,304,597...45,510,653
Ensembl chr19:45,304,031...45,508,709
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G |
Cnn1 |
calponin 1 |
multiple interactions increases expression |
ISO EXP |
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 protein Ascorbic Acid results in increased expression of CNN1 protein |
CTD |
PMID:14639096 PMID:18607632 |
|
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CNR1 protein] |
CTD |
PMID:28285367 |
|
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
|
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CNR2 protein] |
CTD |
PMID:28285367 |
|
NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Cntf |
ciliary neurotrophic factor |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:16896058 |
|
NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877
|
|
G |
Cntn1 |
contactin 1 |
multiple interactions |
ISO |
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of CNTN1 mRNA |
CTD |
PMID:33713149 |
|
NCBI chr 7:123,263,146...123,560,896
Ensembl chr 7:123,372,792...123,558,541
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|
G |
Cntnap1 |
contactin associated protein 1 |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:25555879 |
|
NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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G |
Col10a1 |
collagen type X alpha 1 chain |
increases expression multiple interactions |
ISO |
Ascorbic Acid results in increased expression of COL10A1 mRNA U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of COL10A1 mRNA] |
CTD |
PMID:20530736 |
|
NCBI chr20:38,183,103...38,189,488
Ensembl chr20:38,182,494...38,189,494
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G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression multiple interactions |
ISO |
Ascorbic Acid results in increased expression of COL1A1 mRNA 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA |
CTD |
PMID:12510807 PMID:14566779 PMID:28105418 PMID:31935364 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases expression multiple interactions |
EXP ISO |
Ascorbic Acid results in increased expression of COL1A2 mRNA [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of COL1A2 mRNA |
CTD |
PMID:15372504 PMID:25555879 |
|
NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
|
|
G |
Col2a1 |
collagen type II alpha 1 chain |
increases expression multiple interactions |
EXP ISO |
Ascorbic Acid results in increased expression of COL2A1 mRNA [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]] |
CTD |
PMID:15372504 PMID:26526931 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
|
|
G |
Cr2 |
complement C3d receptor 2 |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CR2 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
|
|
G |
Crip2 |
cysteine-rich protein 2 |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CRIP2 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
|
|
G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid] results in decreased expression of CRP protein |
CTD |
PMID:16517955 |
|
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cryab |
crystallin, alpha B |
increases expression multiple interactions |
EXP ISO |
Ascorbic Acid results in increased expression of CRYAB mRNA [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA |
CTD |
PMID:15372504 PMID:34480604 |
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NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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G |
Cs |
citrate synthase |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] |
CTD |
PMID:27385396 |
|
NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Cspg5 |
chondroitin sulfate proteoglycan 5 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of CSPG5 mRNA |
CTD |
PMID:15305145 |
|
NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758
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G |
Csrp1 |
cysteine and glycine-rich protein 1 |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CSRP1 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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G |
Cst6 |
cystatin E/M |
increases expression |
EXP |
Ascorbic Acid results in increased expression of CST6 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the localization of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein] |
CTD |
PMID:29940330 |
|
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctps2 |
CTP synthase 2 |
multiple interactions |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of CTPS2 mRNA |
CTD |
PMID:25555879 |
|
NCBI chr X:31,645,873...31,786,733
Ensembl chr X:31,645,873...31,786,733
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G |
Ctsd |
cathepsin D |
multiple interactions |
EXP |
[ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] |
CTD |
PMID:17045618 |
|
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsk |
cathepsin K |
increases expression |
ISO |
Ascorbic Acid results in increased expression of CTSK mRNA |
CTD |
PMID:15730627 |
|
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Ctso |
cathepsin O |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of CTSO mRNA |
CTD |
PMID:17639512 |
|
NCBI chr 2:167,230,407...167,254,761
Ensembl chr 2:167,230,330...167,253,702
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
increases expression |
EXP |
Ascorbic Acid deficiency results in increased expression of CXCL1 mRNA; Ascorbic Acid deficiency results in increased expression of CXCL1 protein |
CTD |
PMID:16637227 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
decreases expression increases expression |
ISO |
Ascorbic Acid results in decreased expression of CXCL10 mRNA Ascorbic Acid deficiency results in increased expression of CXCL10 mRNA |
CTD |
PMID:19932582 |
|
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
decreases expression increases expression |
ISO |
Ascorbic Acid results in decreased expression of CXCL6 mRNA Ascorbic Acid deficiency results in increased expression of CXCL6 mRNA |
CTD |
PMID:19932582 |
|
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCL9 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr5 |
C-X-C motif chemokine receptor 5 |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCR5 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein] |
CTD |
PMID:25305479 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
increases expression |
ISO |
Ascorbic Acid results in increased expression of CYBB protein |
CTD |
PMID:21570463 |
|
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cybrd1 |
cytochrome b reductase 1 |
decreases expression increases expression |
ISO |
Ascorbic Acid results in decreased expression of CYBRD1 protein Ascorbic Acid results in increased expression of CYBRD1 protein |
CTD |
PMID:18815723 |
|
NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein] |
CTD |
PMID:23711929 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
Ascorbic Acid inhibits the reaction [Cadmium results in decreased expression of CYP11A1 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP11A1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 mRNA] Ascorbic Acid results in increased expression of CYP11A1 mRNA |
CTD |
PMID:15223132 PMID:16298753 PMID:17280759 PMID:17901237 |
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NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA Ascorbic Acid results in increased expression of CYP19A1 mRNA |
CTD |
PMID:16443354 PMID:17901237 |
|
NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions decreases activity |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CYP1A1 mRNA; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA] Ascorbic Acid results in decreased activity of CYP1A1 protein |
CTD |
PMID:16517059 PMID:17512695 PMID:17639512 PMID:19268519 PMID:21094198 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
increases expression |
EXP |
Ascorbic Acid deficiency results in increased expression of CYP1A2 mRNA; Ascorbic Acid deficiency results in increased expression of CYP1A2 protein |
CTD |
PMID:8269614 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
decreases expression |
EXP |
Ascorbic Acid deficiency results in decreased expression of CYP2B2 protein |
CTD |
PMID:8269614 |
|
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA |
CTD |
PMID:17917374 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases activity multiple interactions |
ISO EXP |
Ascorbic Acid results in decreased activity of CYP2E1 protein [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein] |
CTD |
PMID:17512695 PMID:31585129 PMID:31739238 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA |
CTD |
PMID:17917374 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Dab2 |
DAB adaptor protein 2 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of DAB2 mRNA |
CTD |
PMID:15305145 |
|
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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G |
Dao |
D-amino-acid oxidase |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Diquat results in increased activity of DAO protein] |
CTD |
PMID:33475796 |
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NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
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G |
Dcc |
DCC netrin 1 receptor |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA |
CTD |
PMID:34480604 |
|
NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740
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G |
Dclk1 |
doublecortin-like kinase 1 |
increases expression |
ISO |
Ascorbic Acid results in increased expression of DCLK1 mRNA |
CTD |
PMID:15305145 |
|
NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
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G |
Dcn |
decorin |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
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G |
Dcx |
doublecortin |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA |
CTD |
PMID:34480604 |
|
NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
EXP |
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA |
CTD |
PMID:18544905 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dhrs9 |
dehydrogenase/reductase 9 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of DKK1 mRNA |
CTD |
PMID:19197388 |
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of DKK2 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of DKK2 promoter] |
CTD |
PMID:27901495 |
|
NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225
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G |
Dld |
dihydrolipoamide dehydrogenase |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of and results in increased phosphorylation of DLD protein] |
CTD |
PMID:29158198 |
|
NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions |
ISO |
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in increased expression of DLG4 mRNA Ascorbic Acid inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein] |
CTD |
PMID:33713149 PMID:33872575 |
|
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dlgap5 |
DLG associated protein 5 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of DLGAP5 mRNA |
CTD |
PMID:17639512 |
|
NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] |
CTD |
PMID:25932594 |
|
NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajc10 |
DnaJ heat shock protein family (Hsp40) member C10 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of DNAJC10 mRNA] |
CTD |
PMID:17353921 |
|
NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
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G |
Dnase1 |
deoxyribonuclease 1 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of DNASE1 mRNA |
CTD |
PMID:17639512 |
|
NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
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G |
Dpf1 |
double PHD fingers 1 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPF1 mRNA |
CTD |
PMID:26424790 |
|
NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950
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G |
Dpp4 |
dipeptidylpeptidase 4 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of DPP4 mRNA |
CTD |
PMID:17639512 |
|
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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G |
Dppa2 |
developmental pluripotency-associated 2 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPPA2 mRNA |
CTD |
PMID:28189605 |
|
NCBI chr11:52,549,024...52,556,740
Ensembl chr11:52,549,651...52,556,740
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G |
Dppa5 |
developmental pluripotency associated 5 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of DPPA5A mRNA |
CTD |
PMID:15305145 |
|
NCBI chr 8:79,215,341...79,217,282
Ensembl chr 8:79,215,362...79,216,570 Ensembl chr 7:79,215,362...79,216,570 Ensembl chr 1:79,215,362...79,216,570 Ensembl chr 3:79,215,362...79,216,570
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G |
Dusp6 |
dual specificity phosphatase 6 |
decreases expression |
EXP |
Ascorbic Acid results in decreased expression of DUSP6 mRNA |
CTD |
PMID:15372504 |
|
NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
E2f2 |
E2F transcription factor 2 |
multiple interactions |
ISO |
[BDNF protein co-treated with GDNF protein co-treated with Cyclic AMP co-treated with TGFB3 protein co-treated with Ascorbic Acid] results in decreased expression of E2F2 mRNA |
CTD |
PMID:33713149 |
|
NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
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G |
Ebf3 |
EBF transcription factor 3 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA |
CTD |
PMID:34480604 |
|
NCBI chr 1:191,996,726...192,114,593
Ensembl chr 1:191,996,730...192,114,359
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G |
Ecscr |
endothelial cell surface expressed chemotaxis and apoptosis regulator |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA |
CTD |
PMID:34480604 |
|
NCBI chr18:27,309,711...27,319,106
Ensembl chr18:27,309,718...27,319,032
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G |
Edn1 |
endothelin 1 |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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|
G |
Edn3 |
endothelin 3 |
multiple interactions |
ISO |
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of EDN3 mRNA |
CTD |
PMID:16443354 |
|
NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
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G |
Ednrb |
endothelin receptor type B |
increases expression |
ISO |
Ascorbic Acid results in increased expression of EDNRB mRNA |
CTD |
PMID:15305145 |
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NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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G |
Egfr |
epidermal growth factor receptor |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EGFR mRNA |
CTD |
PMID:21919647 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
multiple interactions |
ISO |
EGLN1 mRNA affects the reaction [Ascorbic Acid results in increased expression of SP7 protein] |
CTD |
PMID:21467157 |
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NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [Quercetin co-treated with Ascorbic Acid] results in increased expression of EGLN3 mRNA |
CTD |
PMID:17639512 PMID:34480604 |
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NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
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G |
Eif2s2 |
eukaryotic translation initiation factor 2 subunit beta |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EIF2S2 mRNA |
CTD |
PMID:19197388 |
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NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
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G |
Eif3a |
eukaryotic translation initiation factor 3, subunit A |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EIF3A mRNA |
CTD |
PMID:19197388 |
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NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
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G |
Eif3c |
eukaryotic translation initiation factor 3, subunit C |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EIF3C mRNA |
CTD |
PMID:19197388 |
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NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
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G |
Eif3i |
eukaryotic translation initiation factor 3, subunit I |
increases expression |
ISO |
Ascorbic Acid results in increased expression of EIF3I mRNA |
CTD |
PMID:22139585 |
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NCBI chr 5:141,935,135...141,942,589
Ensembl chr 5:141,935,044...141,942,676
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G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EIF4A1 mRNA |
CTD |
PMID:19197388 |
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NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858
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G |
Elavl3 |
ELAV like RNA binding protein 3 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 8:20,547,108...20,583,369
Ensembl chr 8:20,550,201...20,583,641
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G |
Elavl4 |
ELAV like RNA binding protein 4 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 5:125,056,848...125,200,543
Ensembl chr 5:125,056,848...125,200,446
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G |
Elp6 |
elongator acetyltransferase complex subunit 6 |
multiple interactions decreases expression |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of ELP6 mRNA Ascorbic Acid results in decreased expression of ELP6 mRNA |
CTD |
PMID:25555879 |
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NCBI chr 8:110,280,059...110,295,070
Ensembl chr 8:110,279,979...110,295,067
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G |
Emp1 |
epithelial membrane protein 1 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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G |
Emp3 |
epithelial membrane protein 3 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNA |
CTD |
PMID:17639512 |
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NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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G |
Emx2 |
empty spiracles homeobox 2 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594
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G |
En1 |
engrailed homeobox 1 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of EN1 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of EN1 promoter] |
CTD |
PMID:27901495 |
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NCBI chr13:31,750,892...31,756,477
Ensembl chr13:31,751,545...31,755,943
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G |
Eno1 |
enolase 1 |
multiple interactions decreases expression |
ISO |
[Ascorbic Acid co-treated with Arsenic Trioxide] results in decreased expression of ENO1 protein; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 mRNA]; Arsenic Trioxide promotes the reaction [Ascorbic Acid results in decreased expression of ENO1 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 mRNA]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in decreased expression of ENO1 protein] Ascorbic Acid results in decreased expression of ENO1 mRNA; Ascorbic Acid results in decreased expression of ENO1 protein |
CTD |
PMID:38160894 |
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NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] |
CTD |
PMID:16288478 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Ephx1 |
epoxide hydrolase 1 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA |
CTD |
PMID:17639512 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Ephx2 |
epoxide hydrolase 2 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNA |
CTD |
PMID:17639512 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Ascorbic Acid results in decreased expression of EPRS1 mRNA |
CTD |
PMID:19197388 |
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NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ercc2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA |
CTD |
PMID:17917374 |
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NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
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G |
Ercc4 |
ERCC excision repair 4, endonuclease catalytic subunit |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA |
CTD |
PMID:17917374 |
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NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 Ensembl chr10:2,419,038...2,448,369
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G |
Ercc5 |
ERCC excision repair 5, endonuclease |
multiple interactions |
ISO |
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA |
CTD |
PMID:17917374 |
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NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA] |
CTD |
PMID:18602937 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
EXP |
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA] |
CTD |
PMID:18602937 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Ezh1 |
enhancer of zeste 1 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of EZH1 mRNA |
CTD |
PMID:26424790 |
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NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 protein; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA] |
CTD |
PMID:26424790 |
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NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] |
CTD |
PMID:23114885 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] |
CTD |
PMID:25062436 PMID:25932594 PMID:32473317 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fabp6 |
fatty acid binding protein 6 |
multiple interactions |
ISO |
[Quercetin co-treated with Ascorbic Acid] results in decreased expression of FABP6 mRNA |
CTD |
PMID:17639512 |
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NCBI chr10:28,063,603...28,068,276
Ensembl chr10:28,063,603...28,068,282
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G |
Fah |
fumarylacetoacetate hydrolase |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA |
CTD |
PMID:34480604 |
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NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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G |
Fancl |
FA complementation group L |
multiple interactions |
ISO |
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of FANCL mRNA |
CTD |
PMID:26424790 |
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NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255
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G |
Fat1 |
FAT atypical cadherin 1 |
multiple interactions increases expression |
ISO |
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FAT1 mRNA Ascorbic Acid results in increased expression of FAT1 mRNA |
CTD |
PMID:25555879 |
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NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
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G |
Fbln1 |
fibulin 1 |
increases expression multiple interactions |
ISO |
Ascorbic Acid results in increased expression of FBLN1 mRNA [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FBLN1 mRNA |
CTD |
PMID:25555879 |
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NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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G |
Fbp1 |
fructose-bisphosphatase 1 |
affects expression |
ISO |
Ascorbic Acid affects the expression of FBP1 protein |
CTD |
PMID:19224539 |
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NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA |
CTD |
PMID:34480604 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fdxr |
ferredoxin reductase |
increases expression |
EXP |
Ascorbic Acid results in increased expression of FDXR mRNA |
CTD |
PMID:15372504 |
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NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658
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G |
Fgb |
fibrinogen beta chain |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA |
CTD |
PMID:34480604 |
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NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions |
ISO |
[[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ABCC1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ACTN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ALDOA mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ASCL1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CDC20 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of CYP24A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of DCX mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ECSCR mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ELAVL4 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of EMX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of ESRG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FAH mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FLT1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXD3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of FOXG1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of GSTP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of H2BC14 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of HES5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of KEAP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of LCK mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of MAFG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OLIG2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of OTX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of POU5F1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SFRP2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SH3BP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SOX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SPTSSB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of SRXN1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in decreased expression of STMN2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of A2M mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ACSL5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AFP mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ALB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of AMHR2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of ANXA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of APOA1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of BMP5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CDH10 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CEACAM6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CIDEC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of COL3A1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CRYAB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP26B1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of CYP3A5 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCC mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DCN mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DHRS9 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of DNAJB1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EBF3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of EGLN3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FABP1 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FBXO32 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGB mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGF7 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FGG mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of FLRT3 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GADD45A mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GATA6 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPR183 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GPX2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GRIA2 mRNA; [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expres | |