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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:d-block element atom
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Accession:CHEBI:33561 term browser browse the term
Synonyms:related_synonym: d-block element;   d-block elements



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cadmium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP70 heat shock protein 70 increases expression EXP Cadmium results in increased expression of HSP70 protein CTD PMID:12915104 NCBI chr12:1,285,282...1,287,670 JBrowse link
cadmium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OCLN occludin decreases expression EXP Cadmium Chloride results in decreased expression of OCLN protein CTD PMID:18418844 NCBI chr 2:54,500,299...54,545,430
Ensembl chr 2:54,500,299...54,545,430
JBrowse link
cobalt atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIP vasoactive intestinal peptide decreases expression EXP Cobalt results in decreased expression of VIP protein CTD PMID:3711722 NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
JBrowse link
copper atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein increases expression EXP Copper results in increased expression of APP protein CTD PMID:16886094 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G COMMD1 copper metabolism domain containing 1 increases abundance
decreases export
EXP COMMD1 gene mutant form results in increased abundance of Copper
COMMD1 gene mutant form results in decreased export of Copper
CTD PMID:20433422 PMID:22879914 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591
JBrowse link
copper(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein increases expression EXP Copper results in increased expression of APP protein CTD PMID:16886094 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G COMMD1 copper metabolism domain containing 1 increases abundance
decreases export
EXP COMMD1 gene mutant form results in increased abundance of Copper
COMMD1 gene mutant form results in decreased export of Copper
CTD PMID:20433422 PMID:22879914 NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591
JBrowse link
iron atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CP ceruloplasmin multiple interactions
increases export
EXP [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron]
CP protein results in increased export of Iron
CTD PMID:16806171 NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
JBrowse link
G LOC477072 serotransferrin multiple interactions
increases export
EXP [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron]
TF protein results in increased export of Iron
CTD PMID:16806171 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845
JBrowse link
iron(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CP ceruloplasmin multiple interactions
increases export
EXP [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron]
CP protein results in increased export of Iron
CTD PMID:16806171 NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
JBrowse link
G LOC477072 serotransferrin multiple interactions
increases export
EXP [CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron]
TF protein results in increased export of Iron
CTD PMID:16806171 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845
JBrowse link
mercury atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 increases expression
multiple interactions
EXP Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein
ABCC1 protein affects the export of and results in decreased susceptibility to Mercury
CTD PMID:15590114 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
EXP Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein
ABCC2 protein affects the export of and results in decreased susceptibility to Mercury
CTD PMID:15590114 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
JBrowse link
mercury dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression
EXP ABCC1 protein affects the export of and results in decreased susceptibility to Mercuric Chloride
Mercuric Chloride results in increased expression of ABCC1 mRNA; Mercuric Chloride results in increased expression of ABCC1 protein
CTD PMID:15590114 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
EXP ABCC2 protein affects the export of and results in decreased susceptibility to Mercuric Chloride
Mercuric Chloride results in increased expression of ABCC2 mRNA; Mercuric Chloride results in increased expression of ABCC2 protein
CTD PMID:15590114 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
JBrowse link
G LOC100686073 metallothionein-1 increases expression EXP Mercuric Chloride results in increased expression of MT1 mRNA CTD PMID:15590114 NCBI chr 2:59,603,021...59,604,173
Ensembl chr 2:59,603,014...59,604,132
JBrowse link
G MT2A metallothionein 1H increases expression EXP Mercuric Chloride results in increased expression of MT2 mRNA CTD PMID:15590114 NCBI chr 2:59,607,926...59,608,825
Ensembl chr 2:59,607,927...59,626,727
JBrowse link
mercury(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC1 ATP binding cassette subfamily C member 1 increases expression
multiple interactions
EXP Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein
ABCC1 protein affects the export of and results in decreased susceptibility to Mercury
CTD PMID:15590114 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
EXP Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein
ABCC2 protein affects the export of and results in decreased susceptibility to Mercury
CTD PMID:15590114 NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
JBrowse link
nitroprusside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G POMC proopiomelanocortin increases expression EXP Nitroprusside results in increased expression of POMC protein CTD PMID:2831029 NCBI chr17:19,431,396...19,438,247
Ensembl chr17:19,431,585...19,434,440
JBrowse link
G REN renin increases activity EXP Nitroprusside results in increased activity of REN protein CTD PMID:2434793 PMID:6399253 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012
JBrowse link
G WT1 WT1 transcription factor multiple interactions EXP [Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of WT1 mRNA CTD PMID:21443142 NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
JBrowse link
zinc oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase decreases activity EXP Zinc Oxide results in decreased activity of CAT protein CTD PMID:28126643 NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501
    chemical entity 501
      atom 498
        metal atom 35
          d-block element atom 15
            chromium group element atom + 0
            cobalt group element atom + 1
            copper group element atom + 2
            d-block molecular entity + 13
            iron group element atom + 5
            lawrencium atom + 0
            lutetium atom + 0
            manganese group element atom + 0
            nickel group element atom + 0
            scandium atom + 0
            titanium group element atom + 0
            vanadium group element atom + 0
            yttrium atom + 0
            zinc group element atom + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 501
    subatomic particle 501
      composite particle 498
        hadron 498
          baryon 501
            nucleon 498
              atomic nucleus 501
                atom 498
                  metal atom 35
                    transition element atom 15
                      d-block element atom 15
                        chromium group element atom + 0
                        cobalt group element atom + 1
                        copper group element atom + 2
                        d-block molecular entity + 13
                        iron group element atom + 5
                        lawrencium atom + 0
                        lutetium atom + 0
                        manganese group element atom + 0
                        nickel group element atom + 0
                        scandium atom + 0
                        titanium group element atom + 0
                        vanadium group element atom + 0
                        yttrium atom + 0
                        zinc group element atom + 7
paths to the root