|
G |
HSP70 |
heat shock protein 70 |
increases expression |
EXP |
Cadmium results in increased expression of HSP70 protein |
CTD |
PMID:12915104 |
|
NCBI chr12:1,285,282...1,287,670
|
|
|
G |
OCLN |
occludin |
decreases expression |
EXP |
Cadmium Chloride results in decreased expression of OCLN protein |
CTD |
PMID:18418844 |
|
NCBI chr 2:54,500,299...54,545,430
Ensembl chr 2:54,500,299...54,545,430
|
|
|
G |
VIP |
vasoactive intestinal peptide |
decreases expression |
EXP |
Cobalt results in decreased expression of VIP protein |
CTD |
PMID:3711722 |
|
NCBI chr 1:42,941,655...42,950,160
Ensembl chr 1:42,941,224...42,950,700
|
|
|
G |
APP |
amyloid beta precursor protein |
increases expression |
EXP |
Copper results in increased expression of APP protein |
CTD |
PMID:16886094 |
|
NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
|
|
G |
COMMD1 |
copper metabolism domain containing 1 |
increases abundance decreases export |
EXP |
COMMD1 gene mutant form results in increased abundance of Copper COMMD1 gene mutant form results in decreased export of Copper |
CTD |
PMID:20433422 PMID:22879914 |
|
NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591
|
|
|
G |
APP |
amyloid beta precursor protein |
increases expression |
EXP |
Copper results in increased expression of APP protein |
CTD |
PMID:16886094 |
|
NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
|
|
G |
COMMD1 |
copper metabolism domain containing 1 |
increases abundance decreases export |
EXP |
COMMD1 gene mutant form results in increased abundance of Copper COMMD1 gene mutant form results in decreased export of Copper |
CTD |
PMID:20433422 PMID:22879914 |
|
NCBI chr10:61,886,281...62,059,610
Ensembl chr10:61,886,281...62,059,591
|
|
|
G |
CP |
ceruloplasmin |
multiple interactions increases export |
EXP |
[CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] CP protein results in increased export of Iron |
CTD |
PMID:16806171 |
|
NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
|
|
G |
LOC477072 |
serotransferrin |
multiple interactions increases export |
EXP |
[CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] TF protein results in increased export of Iron |
CTD |
PMID:16806171 |
|
NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845
|
|
|
G |
CP |
ceruloplasmin |
multiple interactions increases export |
EXP |
[CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] CP protein results in increased export of Iron |
CTD |
PMID:16806171 |
|
NCBI chr23:43,969,297...44,033,226
Ensembl chr23:43,969,435...44,030,369
|
|
G |
LOC477072 |
serotransferrin |
multiple interactions increases export |
EXP |
[CP protein co-treated with TF protein] results in increased export of Iron; CP protein promotes the reaction [TF protein binds to Iron] TF protein results in increased export of Iron |
CTD |
PMID:16806171 |
|
NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845
|
|
|
G |
ABCC1 |
ATP binding cassette subfamily C member 1 |
increases expression multiple interactions |
EXP |
Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein ABCC1 protein affects the export of and results in decreased susceptibility to Mercury |
CTD |
PMID:15590114 |
|
NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
|
|
G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
increases expression multiple interactions |
EXP |
Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein ABCC2 protein affects the export of and results in decreased susceptibility to Mercury |
CTD |
PMID:15590114 |
|
NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
|
|
|
G |
ABCC1 |
ATP binding cassette subfamily C member 1 |
multiple interactions increases expression |
EXP |
ABCC1 protein affects the export of and results in decreased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of ABCC1 mRNA; Mercuric Chloride results in increased expression of ABCC1 protein |
CTD |
PMID:15590114 |
|
NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
|
|
G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
multiple interactions increases expression |
EXP |
ABCC2 protein affects the export of and results in decreased susceptibility to Mercuric Chloride Mercuric Chloride results in increased expression of ABCC2 mRNA; Mercuric Chloride results in increased expression of ABCC2 protein |
CTD |
PMID:15590114 |
|
NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
|
|
G |
LOC100686073 |
metallothionein-1 |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MT1 mRNA |
CTD |
PMID:15590114 |
|
NCBI chr 2:59,603,021...59,604,173
Ensembl chr 2:59,603,014...59,604,132
|
|
G |
MT2A |
metallothionein 1H |
increases expression |
EXP |
Mercuric Chloride results in increased expression of MT2 mRNA |
CTD |
PMID:15590114 |
|
NCBI chr 2:59,607,926...59,608,825
Ensembl chr 2:59,607,927...59,626,727
|
|
|
G |
ABCC1 |
ATP binding cassette subfamily C member 1 |
increases expression multiple interactions |
EXP |
Mercury results in increased expression of ABCC1 mRNA; Mercury results in increased expression of ABCC1 protein ABCC1 protein affects the export of and results in decreased susceptibility to Mercury |
CTD |
PMID:15590114 |
|
NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
|
|
G |
ABCC2 |
ATP binding cassette subfamily C member 2 |
increases expression multiple interactions |
EXP |
Mercury results in increased expression of ABCC2 mRNA; Mercury results in increased expression of ABCC2 protein ABCC2 protein affects the export of and results in decreased susceptibility to Mercury |
CTD |
PMID:15590114 |
|
NCBI chr28:12,670,885...12,740,124
Ensembl chr28:12,670,885...12,740,740
|
|
|
G |
POMC |
proopiomelanocortin |
increases expression |
EXP |
Nitroprusside results in increased expression of POMC protein |
CTD |
PMID:2831029 |
|
NCBI chr17:19,431,396...19,438,247
Ensembl chr17:19,431,585...19,434,440
|
|
G |
REN |
renin |
increases activity |
EXP |
Nitroprusside results in increased activity of REN protein |
CTD |
PMID:2434793 PMID:6399253 |
|
NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012
|
|
G |
WT1 |
WT1 transcription factor |
multiple interactions |
EXP |
[Nitroprusside results in increased abundance of Nitric Oxide] which results in increased expression of WT1 mRNA |
CTD |
PMID:21443142 |
|
NCBI chr18:35,099,660...35,148,767
Ensembl chr18:35,103,934...35,148,000
|
|
|
G |
CAT |
catalase |
decreases activity |
EXP |
Zinc Oxide results in decreased activity of CAT protein |
CTD |
PMID:28126643 |
|
NCBI chr18:33,383,005...33,422,447
Ensembl chr18:33,383,005...33,422,447
|
|