diatomic chlorine - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	diatomic chlorine	go back to main search page
Accession:	CHEBI:33435	browse the term
Synonyms:	related_synonym:	Formula=Cl2

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Genes (380)

dichlorine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP-binding cassette, sub-family B member 1B

increases expression
multiple interactions

Chlorine results in increased expression of ABCB1B mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ABCB1B mRNA

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily C member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ABCC1 mRNA

NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114

G

acyl-CoA dehydrogenase medium chain

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA

NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:242,858,865...242,883,147

G

acetylcholinesterase

multiple interactions

[[Chlorine co-treated with Diazinon] results in increased abundance of diazoxon] which results in decreased activity of ACHE protein

NCBI chr12:25,042,882...25,050,608
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA thioesterase 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ACOT7 mRNA

NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:162,684,645...162,779,309

G

acyl-CoA synthetase long-chain family member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of ACSL1 mRNA
[Ozone co-treated with Chlorine] affects the expression of ACSL1 mRNA

NCBI chr16:52,487,870...52,554,110
Ensembl chr16:45,755,254...45,821,541

G

activin A receptor type 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ACVR1 mRNA

NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:42,978,561...43,098,241

G

adenylate cyclase 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY2 mRNA

NCBI chr 1:36,204,054...36,650,645
Ensembl chr 1:34,375,895...34,822,236

G

adenylate cyclase 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADCY3 mRNA

NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:27,124,828...27,203,686

G

adenylate cyclase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADCY4 mRNA

NCBI chr15:33,236,201...33,252,070
Ensembl chr15:29,266,287...29,282,108

G

adenylate cyclase 5

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY5 mRNA

NCBI chr11:78,976,861...79,123,343
Ensembl chr11:65,471,612...65,618,974

G

adenylate cyclase 8

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADCY8 mRNA

NCBI chr 7:98,306,434...98,555,687
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor L1

decreases expression
multiple interactions

Chlorine results in decreased expression of ADGRL1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:24,204,360...24,244,139

G

adenosine A3 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADORA3 mRNA

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

G

adrenoceptor alpha 2C

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ADRA2C mRNA

NCBI chr14:79,695,514...79,697,476
Ensembl chr14:75,471,143...75,472,846

G

adrenoceptor beta 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512

G

advanced glycosylation end product-specific receptor

decreases expression
increases expression
multiple interactions

Chlorine results in decreased expression of AGER mRNA
Chlorine results in increased expression of AGER protein
[Ozone co-treated with Chlorine] results in increased expression of AGER mRNA

PMID:18636392 PMID:36690086

NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078

G

aldo-keto reductase family 1 member A1

increases expression
multiple interactions

Chlorine results in increased expression of AKR1A1 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA

NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:130,092,732...130,113,674

G

AKT serine/threonine kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921

G

AKT serine/threonine kinase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of AKT2 mRNA

NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817

G

aldolase, fructose-bisphosphate C

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ALDOC mRNA

NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,217,451...63,221,066

G

alpha-methylacyl-CoA racemase

increases expression
multiple interactions

Chlorine results in increased expression of AMACR mRNA
[Ozone co-treated with Chlorine] results in increased expression of AMACR mRNA

NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:59,946,153...59,958,255

G

amphiphysin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of AMPH mRNA

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

annexin A2

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of ANXA2 mRNA
Chlorine results in increased expression of ANXA2 mRNA

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658

G

annexin A3

increases expression
multiple interactions

Chlorine results in increased expression of ANXA3 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ANXA3 mRNA

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617

G

annexin A4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ANXA4 mRNA

NCBI chr 4:120,741,750...120,798,534
Ensembl chr 4:119,184,374...119,241,161

G

annexin A5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ANXA5 mRNA

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:119,314,007...119,353,369

G

APC regulator of WNT signaling pathway

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of APC mRNA

NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696

G

apurinic/apyrimidinic endodeoxyribonuclease 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNA

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785

G

apolipoprotein A1

multiple interactions
affects binding

[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein

NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035

G

apolipoprotein D

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of APOD mRNA

NCBI chr11:82,936,216...82,957,264
Ensembl chr11:69,431,260...69,452,305

G

aquaporin 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of AQP1 mRNA

NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690

G

aquaporin 3 (Gill blood group)

decreases expression
multiple interactions

Chlorine results in decreased expression of AQP3 mRNA
[Ozone co-treated with Chlorine] affects the expression of AQP3 mRNA

NCBI chr 5:61,035,165...61,040,683
Ensembl chr 5:56,239,201...56,244,720

G

ARF GTPase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF1 mRNA

NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434

G

ARF GTPase 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA

NCBI chr 7:131,765,039...131,792,075
Ensembl chr 7:129,886,082...129,912,002

G

ARF GTPase 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ARF4 mRNA

NCBI chr16:1,903,238...1,920,012
Ensembl chr16:1,896,546...1,913,261

G

ARF GTPase 5

increases expression
multiple interactions

Chlorine results in increased expression of ARF5 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ARF5 mRNA

NCBI chr 4:58,003,919...58,006,898
Ensembl chr 4:57,038,521...57,041,441

G

ARF GTPase 6

increases expression
multiple interactions

Chlorine results in increased expression of ARF6 mRNA
[Ozone co-treated with Chlorine] affects the expression of ARF6 mRNA

NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:87,840,142...87,874,114

G

arginase 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of ARG1 mRNA
Chlorine results in increased expression of ARG1 mRNA; Chlorine results in increased expression of ARG1 protein

PMID:18636392 PMID:24582687 PMID:30189237

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422

G

Rho GTPase activating protein 35

decreases expression
multiple interactions

Chlorine results in decreased expression of ARHGAP35 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ARHGAP35 mRNA

NCBI chr 1:86,330,566...86,447,414
Ensembl chr 1:77,202,436...77,319,298

G

arrestin, beta 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of ARRB2 mRNA

NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850

G

activating transcription factor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ATF2 mRNA

NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236

G

ATPase Na+/K+ transporting subunit alpha 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNA
Chlorine results in decreased expression of ATP1A1 mRNA

PMID:18636392 PMID:24218892

NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

decreases expression
multiple interactions

Chlorine results in decreased expression of ATP2A3 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of ATP2A3 mRNA

NCBI chr10:58,079,710...58,111,279
Ensembl chr10:57,582,128...57,612,748

G

ATPase H+ transporting V0 subunit C

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ATP6V0C mRNA

NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,196,204...13,201,500

G

ATPase copper transporting beta

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ATP7B mRNA

NCBI chr16:76,654,725...76,726,092
Ensembl chr16:69,951,778...70,023,636

G

BCL2 associated X, apoptosis regulator

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of BAX mRNA

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368

G

bradykinin receptor B2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of BDKRB2 mRNA

NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497

G

bone morphogenetic protein 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA

NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306

G

complement C5a receptor 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of C5AR1 mRNA

NCBI chr 1:86,077,309...86,088,001

G

calcium voltage-gated channel subunit alpha1 A

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CACNA1A mRNA

NCBI chr19:40,425,560...40,724,810
Ensembl chr19:23,520,741...23,823,225

G

calcium voltage-gated channel subunit alpha1 B

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CACNA1B mRNA

NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:7,380,922...7,546,091

G

calcium voltage-gated channel auxiliary subunit beta 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CACNB3 mRNA

NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074

G

carbonic anhydrase 3

decreases expression
multiple interactions

Chlorine results in decreased expression of CA3 mRNA
[Ozone co-treated with Chlorine] affects the expression of CA3 mRNA

NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280

G

CART prepropeptide

decreases expression
multiple interactions

Chlorine results in decreased expression of CARTPT mRNA
[Ozone co-treated with Chlorine] affects the expression of CARTPT mRNA

NCBI chr 2:32,989,215...32,991,794
Ensembl chr 2:31,255,098...31,290,713

G

caspase 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CASP3 mRNA

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648

G

calcium-sensing receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CASR mRNA

NCBI chr11:77,738,398...77,813,639
Ensembl chr11:64,235,251...64,304,811

G

calpastatin

increases expression
multiple interactions

Chlorine results in increased expression of CAST mRNA
[Ozone co-treated with Chlorine] affects the expression of CAST mRNA

NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659

G

catalase

increases expression
multiple interactions

Chlorine results in increased expression of CAT protein
Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]

PMID:35065218 PMID:36690086

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478

G

cholecystokinin B receptor

decreases expression
multiple interactions

Chlorine results in decreased expression of CCKBR mRNA
[Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA

NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:159,771,733...159,814,881

G

C-C motif chemokine ligand 11

increases expression

Chlorine results in increased expression of CCL11 protein

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 12

increases expression

Chlorine results in increased expression of CCL12 mRNA

NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,070,230...67,071,780

G

C-C motif chemokine ligand 2

increases expression
multiple interactions
decreases secretion

Chlorine results in increased expression of CCL2 mRNA; Chlorine results in increased expression of CCL2 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]

PMID:23146759 PMID:24582687 PMID:30189237 PMID:35065218

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

increases expression

Chlorine results in increased expression of CCL20 mRNA

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 3

increases expression

Chlorine results in increased expression of CCL3 protein

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

increases expression
multiple interactions

Chlorine results in increased expression of CCL5 protein
[Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA

PMID:23146759 PMID:31066272

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

increases expression

Chlorine results in increased expression of CCL7 mRNA

NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,016,446...67,018,303

G

C-C motif chemokine ligand 9

increases expression

Chlorine results in increased expression of CCL6 mRNA

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,366,487...68,371,369

G

cyclin C

increases expression
multiple interactions

Chlorine results in increased expression of CCNC mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CCNC mRNA

NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:35,266,823...35,296,584

G

cyclin D1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCND1 mRNA

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA

NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371

G

cyclin G1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CCNG1 mRNA

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641

G

Cd4 molecule

decreases expression
multiple interactions

Chlorine results in decreased expression of CD4 mRNA
[Ozone co-treated with Chlorine] affects the expression of CD4 mRNA

NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:157,668,878...157,695,191

G

CD44 molecule

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620

G

CD9 molecule

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CD9 mRNA

NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:158,256,328...158,289,222

G

cell division cycle 25B

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CDC25B mRNA

NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:118,407,128...118,417,272

G

cadherin 22

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:153,845,787...153,970,588

G

cyclin-dependent kinase 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA

NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

Chlorine results in increased expression of CDKN1A mRNA
[Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 2B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CDKN2B mRNA

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050

G

cofilin 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CFL1 mRNA

NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587

G

CF transmembrane conductance regulator

multiple interactions
increases transport

CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]
CFTR protein results in increased transport of Chlorine

PMID:12612912 PMID:21765217

NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756

G

cholinergic receptor nicotinic alpha 1 subunit

increases expression
multiple interactions

Chlorine results in increased expression of CHRNA1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CHRNA1 mRNA

NCBI chr 3:78,862,286...78,877,353
Ensembl chr 3:58,454,744...58,469,840

G

cholinergic receptor nicotinic alpha 4 subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CHRNA4 mRNA

NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:168,136,266...168,156,957

G

cholinergic receptor nicotinic beta 1 subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CHRNB1 mRNA

NCBI chr10:54,999,943...55,015,137
Ensembl chr10:54,501,093...54,516,345

G

creatine kinase, mitochondrial 1

affects expression
multiple interactions

Chlorine affects the expression of CKMT1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CKMT1 mRNA

NCBI chr 3:128,783,408...128,789,485
Ensembl chr 3:108,330,705...108,335,758

G

C-type lectin domain family 4, member D

increases expression

Chlorine results in increased expression of CLEC4D mRNA

NCBI chr 4:158,275,287...158,286,978
Ensembl chr 4:156,589,792...156,598,848

G

clusterin

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of CLU mRNA
Chlorine results in increased expression of CLU protein
Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein]

PMID:18636392 PMID:35065218

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315

G

chemerin chemokine-like receptor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA

NCBI chr12:48,634,929...48,687,833
Ensembl chr12:42,974,410...43,028,129

G

calponin 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

cannabinoid receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CNR1 mRNA

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:48,408,574...48,435,099

G

carboxypeptidase D

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CPD mRNA

NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491

G

carnitine palmitoyltransferase 1B

increases expression
multiple interactions

Chlorine results in increased expression of CPT1B mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CPT1B mRNA

NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:120,491,354...120,500,404

G

corticotropin releasing hormone receptor 2

increases expression
multiple interactions

Chlorine results in increased expression of CRHR2 mRNA
[Ozone co-treated with Chlorine] affects the expression of CRHR2 mRNA

NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:84,224,002...84,265,904

G

CRK proto-oncogene, adaptor protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CRK mRNA

NCBI chr10:61,028,736...61,054,971
Ensembl chr10:60,530,464...60,553,406

G

colony stimulating factor 1 receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of CSF1R mRNA

NCBI chr18:56,834,152...56,860,804
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 2

increases expression

Chlorine results in increased expression of CSF2 protein

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

increases expression
multiple interactions

Chlorine results in increased expression of CSF3 mRNA
Chlorine results in increased expression of CSF3 protein
[Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA

PMID:18636392 PMID:23146759

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603

G

casein kinase 1, gamma 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in increased expression of CSNK1G1 mRNA
Chlorine results in decreased expression of CSNK1G1 mRNA

NCBI chr 8:75,334,751...75,472,339
Ensembl chr 8:66,439,864...66,572,826

G

cysteine and glycine rich protein 3

increases expression
multiple interactions

Chlorine results in increased expression of CSRP3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CSRP3 mRNA

NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:98,528,068...98,546,653

G

cathepsin B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNA

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:37,389,629...37,410,500

G

cathepsin L

increases expression
multiple interactions

Chlorine results in increased expression of CTSL mRNA
[Ozone co-treated with Chlorine] results in decreased expression of CTSL mRNA

NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548

G

C-X-C motif chemokine ligand 10

decreases expression
multiple interactions

Chlorine results in decreased expression of CXCL10 mRNA
[Ozone co-treated with Chlorine] results in increased expression of CXCL10 mRNA

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 3

multiple interactions
increases expression

triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein]
Chlorine results in increased expression of CXCL1 mRNA; Chlorine results in increased expression of CXCL1 protein

PMID:20348278 PMID:20819911 PMID:23146759 PMID:24582687

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of CXCR4 mRNA

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of CYP11A1 mRNA

NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA
Chlorine results in increased expression of CYP19A1 mRNA

NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, subfamily 2, polypeptide 11

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP2C mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 4, subfamily a, polypeptide 3

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP4A3 mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP4A3 mRNA

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 4, subfamily f, polypeptide 4

decreases expression
multiple interactions

Chlorine results in decreased expression of CYP4F4 mRNA
[Ozone co-treated with Chlorine] affects the expression of CYP4F4 mRNA

NCBI chr 7:12,367,711...12,384,010
Ensembl chr 7:11,717,208...11,733,506

G

dopa decarboxylase

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of DDC mRNA
Chlorine results in decreased expression of DDC mRNA

NCBI chr14:90,592,304...90,682,830
Ensembl chr14:86,378,685...86,469,208

G

DNA-damage inducible transcript 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201

G

dipeptidylpeptidase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of DPP4 mRNA

NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:46,962,243...47,043,901

G

dipeptidyl peptidase like 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of DPP6 mRNA

NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532

G

dopamine receptor D1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of DRD1 mRNA

NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,540,558...10,545,002

G

eukaryotic translation elongation factor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA

NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183

G

early growth response 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of EGR1 mRNA

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA

NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

coagulation factor II, thrombin

decreases expression
multiple interactions

Chlorine results in decreased expression of F2 mRNA
[Ozone co-treated with Chlorine] affects the expression of F2 mRNA

NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486

G

fatty acid amide hydrolase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of FAAH mRNA

NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:129,479,824...129,498,677

G

fatty acid binding protein 1

decreases expression
multiple interactions

Chlorine results in decreased expression of FABP1 mRNA
[Ozone co-treated with Chlorine] affects the expression of FABP1 mRNA

NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788

G

fatty acid binding protein 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of FABP2 mRNA

NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089

G

fatty acid binding protein 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of FABP4 mRNA

NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid binding protein 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA

NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:91,765,056...91,853,773

G

Fas cell surface death receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FAS mRNA

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591

G

fibroblast growth factor 10

decreases expression
multiple interactions

Chlorine results in decreased expression of FGF10 mRNA
[Ozone co-treated with Chlorine] affects the expression of FGF10 mRNA

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866

G

fibroblast growth factor 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of FGF2 mRNA
Chlorine results in decreased expression of FGF2 mRNA

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221

G

FGR proto-oncogene, Src family tyrosine kinase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of FGR mRNA

NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:145,189,841...145,217,326

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression
multiple interactions

Chlorine results in decreased expression of FOS mRNA
[Ozone co-treated with Chlorine] affects the expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of FOSL1 mRNA

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930

G

gamma-aminobutyric acid type B receptor subunit 1

decreases expression
multiple interactions

Chlorine results in decreased expression of GABBR1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GABBR1 mRNA

NCBI chr20:1,469,779...1,499,352
Ensembl chr20:1,464,534...1,493,994

G

galanin receptor 1

decreases expression
multiple interactions

Chlorine results in decreased expression of GALR1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GALR1 mRNA

NCBI chr18:78,046,803...78,062,359
Ensembl chr18:75,772,023...75,787,577

G

glyceraldehyde-3-phosphate dehydrogenase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235

G

glucagon receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GCGR mRNA

NCBI chr10:106,306,803...106,314,970
Ensembl chr10:105,808,473...105,816,640

G

glutamate cysteine ligase, modifier subunit

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535

G

GDP dissociation inhibitor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GDI1 mRNA

NCBI chr X:157,238,900...157,245,562
Ensembl chr X:152,087,444...152,094,272

G

GDP dissociation inhibitor 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GDI2 mRNA

NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366

G

growth hormone receptor

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GHR mRNA
Chlorine results in decreased expression of GHR mRNA

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:52,542,594...52,804,735

G

gastric inhibitory polypeptide receptor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GIPR mRNA

NCBI chr 1:87,932,316...87,956,084
Ensembl chr 1:78,805,593...78,814,462

G

glia maturation factor, beta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA

NCBI chr15:22,549,705...22,560,125
Ensembl chr15:20,067,263...20,080,331

G

G protein subunit alpha i1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAI1 mRNA

NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:16,814,001...16,896,417

G

G protein subunit alpha i2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA

NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit alpha o1

decreases expression
multiple interactions

Chlorine results in decreased expression of GNAO1 mRNA
[Ozone co-treated with Chlorine] affects the expression of GNAO1 mRNA

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,035,956...11,192,493

G

GNAS complex locus

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA

NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein subunit alpha z

increases expression
multiple interactions

Chlorine results in increased expression of GNAZ mRNA
[Ozone co-treated with Chlorine] results in increased expression of GNAZ mRNA

NCBI chr20:13,642,853...13,693,616
Ensembl chr20:13,644,640...13,669,907

G

G protein subunit beta 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of GNB1 mRNA

NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:166,075,629...166,142,124

G

glutathione peroxidase 3

increases expression
multiple interactions

Chlorine results in increased expression of GPX3 mRNA
[Ozone co-treated with Chlorine] affects the expression of GPX3 mRNA

NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 5

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of GPX5 mRNA
Chlorine results in increased expression of GPX5 mRNA

NCBI chr17:43,436,126...43,443,074
Ensembl chr17:43,416,340...43,443,074

G

G protein-coupled receptor kinase 3

increases expression
multiple interactions

Chlorine results in increased expression of GRK3 mRNA
[Ozone co-treated with Chlorine] results in increased expression of GRK3 mRNA

NCBI chr12:49,285,228...49,395,803
Ensembl chr12:43,624,897...43,731,262

G

glutathione-disulfide reductase

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GSR mRNA

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661

G

glutathione synthetase

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA
Chlorine results in increased expression of GSS mRNA

NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:144,047,850...144,078,198

G

glutathione S-transferase alpha 4

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GSTA4 mRNA
Chlorine results in decreased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase kappa 1

increases expression
multiple interactions

Chlorine results in increased expression of GSTK1 mRNA
[Ozone co-treated with Chlorine] affects the expression of GSTK1 mRNA

NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase mu 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNA
Chlorine results in decreased expression of GSTM2 mRNA

NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase theta 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,053...12,822,724
Ensembl chr20:12,819,170...12,823,288

G

guanylate cyclase 2E

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of GUCY2D mRNA

NCBI chr10:54,453,753...54,478,639
Ensembl chr10:53,959,010...53,974,067

G

H2A.X variant histone

increases expression

Chlorine results in increased expression of H2AX protein

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

decreases expression
multiple interactions

Chlorine results in decreased expression of HMGCS2 mRNA
[Ozone co-treated with Chlorine] affects the expression of HMGCS2 mRNA

NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:185,875,616...185,902,130

G

heme oxygenase 1

increases expression

Chlorine results in increased expression of HMOX1 protein

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079

G

heme oxygenase 2

increases expression

Chlorine results in increased expression of HMOX2 protein

NCBI chr10:11,303,512...11,337,640
Ensembl chr10:10,797,055...10,831,148

G

hippocalcin-like 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HPCAL4 mRNA

NCBI chr 5:140,739,577...140,751,529
Ensembl chr 5:135,454,540...135,466,416

G

hypoxanthine phosphoribosyltransferase 1

increases expression
multiple interactions

Chlorine results in increased expression of HPRT1 mRNA
[Ozone co-treated with Chlorine] affects the expression of HPRT1 mRNA

NCBI chr X:137,655,744...137,687,718
Ensembl chr X:132,736,096...132,768,154

G

HRas proto-oncogene, GTPase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of HRAS mRNA

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of HSD3B1 mRNA
[Ozone co-treated with Chlorine] affects the expression of HSD3B1 mRNA

NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999

G

heat shock protein family A (Hsp70) member 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family D (Hsp60) member 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of HSPD1 mRNA
Chlorine results in increased expression of HSPD1 protein
Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]

PMID:18636392 PMID:35065218

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662

G

5-hydroxytryptamine receptor 1F

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HTR1F mRNA

NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150

G

5-hydroxytryptamine receptor 6

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of HTR6 mRNA

NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:151,296,662...151,311,912

G

huntingtin

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of HTT mRNA

NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070

G

inhibitor of DNA binding 2

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of ID2 mRNA
Chlorine results in decreased expression of ID2 mRNA

NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400

G

interferon gamma

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of IFNG mRNA
Chlorine results in increased expression of IFNG protein

PMID:18636392 PMID:23146759

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor binding protein, acid labile subunit

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNA

NCBI chr10:14,397,076...14,408,439
Ensembl chr10:13,898,395...13,902,677

G

insulin-like growth factor binding protein 3

decreases expression
multiple interactions

Chlorine results in decreased expression of IGFBP3 mRNA
[Ozone co-treated with Chlorine] affects the expression of IGFBP3 mRNA

NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083

G

interleukin 12A

increases expression

Chlorine results in increased expression of IL12A protein

NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 12B

increases expression

Chlorine results in increased expression of IL12B protein

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903

G

interleukin 13

increases expression

Chlorine results in increased expression of IL13 protein

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737

G

interleukin 18

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

multiple interactions
affects expression
increases expression

[Ozone co-treated with Chlorine] results in increased expression of IL1B mRNA
[Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein
Chlorine affects the expression of IL1B mRNA
Chlorine results in increased expression of IL1B protein

PMID:18636392 PMID:23146759 PMID:24582687 PMID:31066272

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of IL1RL1 mRNA
Chlorine results in decreased expression of IL1RL1 mRNA

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 4 receptor

increases expression

Chlorine results in increased expression of IL4RA mRNA

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 6

increases expression
decreases secretion
multiple interactions

Chlorine results in increased expression of IL6 mRNA; Chlorine results in increased expression of IL6 protein
Chlorine results in decreased secretion of IL6 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]

PMID:23146759 PMID:30189237 PMID:35065218

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178

G

inhibin subunit beta A

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of INHBA mRNA

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982

G

insulin receptor-related receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of INSRR mRNA

NCBI chr 2:175,553,244...175,572,676
Ensembl chr 2:173,255,414...173,274,800

G

integrin subunit alpha 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ITGA1 mRNA

NCBI chr 2:48,379,181...48,545,336
Ensembl chr 2:46,653,193...46,812,238

G

integrin subunit beta 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ITGB1 mRNA

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195

G

inositol 1,4,5-trisphosphate receptor, type 3

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of ITPR3 mRNA

NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,136,441...5,202,337

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression
multiple interactions

Chlorine results in decreased expression of JUN mRNA
[Ozone co-treated with Chlorine] affects the expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656

G

junction plakoglobin

increases expression
multiple interactions

Chlorine results in increased expression of JUP mRNA
[Ozone co-treated with Chlorine] results in decreased expression of JUP mRNA

NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,300,440...85,327,057

G

potassium voltage-gated channel subfamily A member 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNA4 mRNA

NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162

G

potassium voltage-gated channel subfamily B member 1

affects expression
multiple interactions

Chlorine affects the expression of KCNB1 mRNA
[Ozone co-treated with Chlorine] affects the expression of KCNB1 mRNA

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

G

potassium voltage-gated channel subfamily D member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of KCND2 mRNA

NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:49,776,246...50,277,728

G

potassium inwardly-rectifying channel, subfamily J, member 4

decreases expression
multiple interactions

Chlorine results in decreased expression of KCNJ4 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of KCNJ4 mRNA

NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:111,047,094...111,074,151

G

potassium inwardly-rectifying channel, subfamily J, member 5

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNJ5 mRNA

NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:30,724,925...30,753,518

G

potassium inwardly-rectifying channel, subfamily J, member 8

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of KCNJ8 mRNA

NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:175,508,912...175,515,603

G

kallikrein B1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of KLKB1 mRNA

NCBI chr16:53,690,180...53,714,570
Ensembl chr16:46,958,707...46,982,053

G

KRAS proto-oncogene, GTPase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNA

NCBI chr 4:179,916,255...179,949,613

G

lecithin cholesterol acyltransferase

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of LCAT mRNA
[MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein
Chlorine results in decreased expression of LCAT mRNA

PMID:18636392 PMID:33861588

NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231

G

LIM domain kinase 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of LIMK1 mRNA

NCBI chr12:27,663,177...27,697,085
Ensembl chr12:22,026,672...22,060,606

G

lipase C, hepatic type

decreases expression
multiple interactions

Chlorine results in decreased expression of LIPC mRNA
[Ozone co-treated with Chlorine] results in increased expression of LIPC mRNA

NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:71,509,635...71,635,464

G

lipase E, hormone sensitive type

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of LIPE mRNA

NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:80,965,627...80,984,310

G

LYN proto-oncogene, Src family tyrosine kinase

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of LYN mRNA
Chlorine results in increased expression of LYN mRNA

NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:16,639,466...16,756,868

G

mal, T-cell differentiation protein

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mitogen activated protein kinase kinase 1

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of MAP2K1 mRNA
Chlorine results in increased expression of MAP2K1 mRNA

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAPK1 mRNA

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAPK3 mRNA

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863

G

MYC associated factor X

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA

NCBI chr 6:101,369,989...101,395,333
Ensembl chr 6:95,636,858...95,662,137

G

melanocortin 4 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MC4R mRNA

NCBI chr18:62,689,798...62,691,685
Ensembl chr18:60,419,832...60,421,719

G

methyl CpG binding protein 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MECP2 mRNA

NCBI chr X:156,932,481...156,995,981
Ensembl chr X:151,789,930...151,844,689

G

mesenchyme homeobox 2

affects expression
multiple interactions

Chlorine affects the expression of MEOX2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of MEOX2 mRNA

NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:53,856,758...53,917,467

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNA

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756

G

microsomal glutathione S-transferase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of MGST1 mRNA
[Ozone co-treated with Chlorine] affects the expression of MGST1 mRNA

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:171,029,630...171,044,892

G

matrix metallopeptidase 14

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MMP14 mRNA

NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 9

decreases secretion
increases expression
multiple interactions

Chlorine results in decreased secretion of MMP9 protein
Chlorine results in increased expression of MMP9 protein
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]

PMID:35065218 PMID:36690086

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120

G

myeloid cell nuclear differentiation antigen

increases expression

Chlorine results in increased expression of IFI204 mRNA

NCBI chr13:88,550,224...88,567,892
Ensembl chr13:86,017,892...86,034,201

G

myeloperoxidase

multiple interactions

[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein; MPO protein promotes the reaction [chlorodimedone binds to Chlorine]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]]

PMID:31288001 PMID:33861588

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819

G

mannose receptor, C type 1

increases expression

Chlorine results in increased expression of MRC1 mRNA

NCBI chr17:82,157,725...82,239,411
Ensembl chr17:77,249,187...77,330,857

G

MAS related GPR family member F

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of MRGPRF mRNA

NCBI chr 1:209,893,384...209,902,852
Ensembl chr 1:200,463,973...200,473,660

G

melatonin receptor 1A

decreases expression
multiple interactions

Chlorine results in decreased expression of MTNR1A mRNA
[Ozone co-treated with Chlorine] results in increased expression of MTNR1A mRNA

NCBI chr16:53,876,964...53,896,421
Ensembl chr16:47,144,461...47,163,919

G

major vault protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of MVP mRNA

NCBI chr 1:191,025,259...191,052,866
Ensembl chr 1:181,594,734...181,622,380

G

myosin Ib

increases expression
multiple interactions

Chlorine results in increased expression of MYO1B mRNA
[Ozone co-treated with Chlorine] affects the expression of MYO1B mRNA

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:49,690,086...49,850,798

G

neural EGFL like 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NELL1 mRNA

NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860

G

neural EGFL like 2

increases expression
multiple interactions

Chlorine results in increased expression of NELL2 mRNA
[Ozone co-treated with Chlorine] results in increased expression of NELL2 mRNA

NCBI chr 7:126,343,089...126,662,903
Ensembl chr 7:126,198,851...126,733,503

G

NFKB inhibitor alpha

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of NFKBIA mRNA
Chlorine results in decreased expression of NFKBIA mRNA

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941

G

neuroglobin

affects abundance

NGB protein affects the abundance of Chlorine

NCBI chr 6:112,475,332...112,480,786
Ensembl chr 6:106,744,378...106,749,830

G

NME/NM23 nucleoside diphosphate kinase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NME2 mRNA

NCBI chr10:79,394,999...79,400,418
Ensembl chr10:78,897,770...78,903,538
Ensembl chr20:78,897,770...78,903,538

G

nitric oxide synthase 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NOS1 mRNA

NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945

G

nitric oxide synthase 2

increases expression

Chlorine results in increased expression of NOS2 mRNA

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

decreases activity
decreases expression

Chlorine results in decreased activity of NOS3 protein
Chlorine results in decreased expression of NOS3 protein

NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166

G

natriuretic peptide C

multiple interactions
affects expression

[Ozone co-treated with Chlorine] affects the expression of NPPC mRNA
Chlorine affects the expression of NPPC mRNA

NCBI chr 9:94,767,986...94,772,186
Ensembl chr 9:87,320,051...87,324,251

G

neuronal pentraxin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA

NCBI chr 7:113,217,046...113,235,122
Ensembl chr 7:111,336,664...111,354,802

G

nuclear receptor subfamily 2, group C, member 2

decreases expression
multiple interactions

Chlorine results in decreased expression of NR2C2 mRNA
[Ozone co-treated with Chlorine] affects the expression of NR2C2 mRNA

NCBI chr 4:126,167,350...126,223,942
Ensembl chr 4:124,608,960...124,661,902

G

nuclear receptor subfamily 2, group F, member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA

NCBI chr 2:9,776,179...9,785,924
Ensembl chr 2:8,040,377...8,050,123

G

nuclear receptor subfamily 3, group C, member 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA

NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885

G

nuclear receptor subfamily 4, group A, member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of NR4A1 mRNA
[Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297

G

nuclear receptor subfamily 4, group A, member 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733

G

neuropilin 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of NRP2 mRNA

NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:64,123,132...64,237,958

G

neurexin 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NRXN1 mRNA

NCBI chr 6:8,931,360...10,077,381
Ensembl chr 6:3,177,897...4,322,710

G

neurexin 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NRXN2 mRNA

NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:203,735,753...203,842,297

G

neurotrophic receptor tyrosine kinase 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of NTRK1 mRNA

NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770

G

neurotensin receptor 2

decreases expression
multiple interactions

Chlorine results in decreased expression of NTSR2 mRNA
[Ozone co-treated with Chlorine] affects the expression of NTSR2 mRNA

NCBI chr 6:39,424,297...39,431,015
Ensembl chr 6:39,424,324...39,431,014

G

ornithine decarboxylase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of ODC1 mRNA

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:40,329,964...40,336,440

G

opioid receptor, kappa 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNA
Chlorine results in decreased expression of OPRK1 mRNA

NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823

G

p21 (RAC1) activated kinase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PAK1 mRNA

NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:152,111,188...152,226,383

G

proliferating cell nuclear antigen

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PCNA mRNA

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995

G

proprotein convertase subtilisin/kexin type 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PCSK7 mRNA

NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705

G

PDGFA associated protein 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PDAP1 mRNA

NCBI chr12:14,584,414...14,594,641
Ensembl chr12:9,470,574...9,535,374

G

phosphodiesterase 4D

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PDE4D mRNA

NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884

G

platelet derived growth factor receptor beta

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843

G

protein disulfide isomerase family A, member 4

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA
Chlorine results in increased expression of PDIA4 mRNA

NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:76,803,198...76,822,107

G

PDZ and LIM domain 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PDLIM1 mRNA

NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:239,042,385...239,091,076

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA

NCBI chr 8:118,522,371...118,565,478
Ensembl chr 8:109,643,937...109,685,634

G

post-GPI attachment to proteins 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PGAP2 mRNA

NCBI chr 1:166,003,593...166,030,088
Ensembl chr 1:156,591,615...156,618,114

G

prohibitin 1

increases expression
multiple interactions

Chlorine results in increased expression of PHB1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of PHB1 mRNA

NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042

G

phosphatidylinositol 4-kinase alpha

decreases expression
multiple interactions

Chlorine results in decreased expression of PI4KA mRNA
[Ozone co-treated with Chlorine] affects the expression of PI4KA mRNA

NCBI chr11:83,609,148...83,726,876
Ensembl chr11:83,609,069...83,724,080

G

phospholipase A2, group IIC

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PLA2G2C mRNA

NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:150,959,182...150,981,377

G

placenta associated 8

increases expression

Chlorine results in increased expression of PLAC8 mRNA

NCBI chr14:9,356,950...9,378,586
Ensembl chr14:9,063,048...9,074,264

G

plasminogen activator, tissue type

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNA

NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223

G

plectin

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA

NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:107,887,764...107,945,467

G

phospholipid phosphatase 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in decreased expression of PLPP1 mRNA
Chlorine results in decreased expression of PLPP1 mRNA

NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:44,438,994...44,501,268

G

peripheral myelin protein 22

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PMP22 mRNA

NCBI chr10:48,294,932...48,324,941
Ensembl chr10:47,795,709...47,825,714

G

pancreatic lipase

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of PNLIP mRNA

NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:257,798,581...257,811,654

G

protein phosphatase 2 catalytic subunit alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PPP2CA mRNA

NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 2 catalytic subunit beta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PPP2CB mRNA

NCBI chr16:65,261,178...65,282,658
Ensembl chr16:58,558,122...58,579,576

G

peroxiredoxin 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194

G

protein arginine methyltransferase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PRMT1 mRNA

NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:95,458,850...95,468,345

G

proteasome 20S subunit alpha 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA1 mRNA

NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:168,440,936...168,453,472

G

proteasome 20S subunit alpha 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA2 mRNA

NCBI chr17:55,250,054...55,260,441
Ensembl chr17:50,551,924...50,564,938

G

proteasome 20S subunit alpha 3

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of PSMA3L mRNA
Chlorine results in increased expression of PSMA3L mRNA

NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965

G

proteasome 20S subunit alpha 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMA4 mRNA

NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890

G

proteasome 20S subunit beta 3

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 4

increases expression
multiple interactions

Chlorine results in increased expression of PSMB4 mRNA
[Ozone co-treated with Chlorine] affects the expression of PSMB4 mRNA

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

proteasome 20S subunit beta 6

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB6 mRNA

NCBI chr10:55,239,256...55,241,586
Ensembl chr10:55,239,241...55,241,586

G

proteasome 20S subunit beta 8

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,652,159...4,655,283

G

proteasome 26S subunit, ATPase 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNA

NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123

G

proteasome 26S subunit, ATPase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PSMC2 mRNA

NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185

G

proteasome 26S subunit, ATPase 4

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA

NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:83,348,592...83,357,494

G

proteasome 26S subunit, ATPase 5

increases expression
multiple interactions

Chlorine results in increased expression of PSMC5 mRNA
[Ozone co-treated with Chlorine] affects the expression of PSMC5 mRNA

NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135

G

platelet-activating factor receptor

increases expression
multiple interactions

Chlorine results in increased expression of PTAFR mRNA
[Ozone co-treated with Chlorine] affects the expression of PTAFR mRNA

NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:144,765,976...144,795,251

G

prostaglandin-endoperoxide synthase 2

increases expression

Chlorine results in increased expression of PTGS2 mRNA

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188

G

pleiotrophin

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of PTN mRNA
Chlorine results in increased expression of PTN mRNA

NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:65,293,734...65,375,456

G

protein tyrosine phosphatase, non-receptor type 11

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of PTPN11 mRNA

NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925

G

protein tyrosine phosphatase, non-receptor type 7

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of PTPN7 mRNA

NCBI chr13:46,570,904...46,584,048
Ensembl chr13:46,571,712...46,583,308

G

protein tyrosine phosphatase, receptor type, R

decreases expression
multiple interactions

Chlorine results in decreased expression of PTPRR mRNA
[Ozone co-treated with Chlorine] affects the expression of PTPRR mRNA

NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603

G

RAB15, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB15 mRNA
[Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA

NCBI chr 6:95,499,584...95,524,073
Ensembl chr 6:95,499,587...95,523,942

G

RAB1A, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB1A mRNA
[Ozone co-treated with Chlorine] affects the expression of RAB1A mRNA

NCBI chr14:98,623,582...98,648,766
Ensembl chr14:94,415,275...94,448,248

G

RAB2A, member RAS oncogene family

increases expression
multiple interactions

Chlorine results in increased expression of RAB2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of RAB2 mRNA

NCBI chr 5:21,676,017...21,740,035
Ensembl chr 5:21,676,129...21,739,899

G

RAB3B, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA

NCBI chr 5:128,859,034...128,926,087
Ensembl chr 5:123,644,423...123,697,401

G

RAB3D, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA

NCBI chr 8:28,714,706...28,725,379
Ensembl chr 8:20,439,294...20,449,185

G

RAB4A, member RAS oncogene family

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RAB4A mRNA

NCBI chr19:68,692,228...68,720,169
Ensembl chr19:51,795,613...51,822,703

G

RAS like proto-oncogene A

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of RALA mRNA

NCBI chr17:51,787,682...51,840,738
Ensembl chr17:47,092,207...47,144,063

G

ral guanine nucleotide dissociation stimulator

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of RALGDS mRNA
Chlorine results in increased expression of RALGDS mRNA

NCBI chr 3:32,237,644...32,278,045
Ensembl chr 3:11,839,416...11,880,059

G

RAS p21 protein activator 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RASA1 mRNA

NCBI chr 2:17,593,136...17,676,707
Ensembl chr 2:15,857,980...15,940,854

G

regulating synaptic membrane exocytosis 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA

NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631

G

Ras and Rab interactor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RIN1 mRNA

NCBI chr 1:211,785,107...211,789,755
Ensembl chr 1:202,355,890...202,362,729

G

arginyl aminopeptidase

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RNPEP mRNA

NCBI chr13:49,251,259...49,271,440
Ensembl chr13:46,699,463...46,717,998

G

ribosomal protein L10

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNA

NCBI chr X:157,205,850...157,208,057
Ensembl chr X:152,054,452...152,056,761

G

ribosomal protein L11

increases expression
multiple interactions

Chlorine results in increased expression of RPL11 mRNA
[Ozone co-treated with Chlorine] affects the expression of RPL11 mRNA

NCBI chr 5:153,557,592...153,561,230
Ensembl chr 5:148,274,069...148,277,599

G

ribosomal protein L12

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL12 mRNA

NCBI chr 3:36,661,940...36,664,314
Ensembl chr 3:16,264,251...16,266,642

G

ribosomal protein L13

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL13 mRNA

NCBI chr19:68,062,442...68,065,065
Ensembl chr19:51,153,924...51,163,014
Ensembl chr 3:51,153,924...51,163,014

G

ribosomal protein L21

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL21 mRNA

NCBI chr12:8,268,641...8,272,278
Ensembl chr12:8,267,196...8,272,281
Ensembl chr 3:8,267,196...8,272,281
Ensembl chr13:8,267,196...8,272,281

G

ribosomal protein L36A like 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPL36AL mRNA

NCBI chr 6:93,390,864...93,392,258
Ensembl chr X:97,766,179...97,768,892
Ensembl chr10:97,766,179...97,768,892
Ensembl chr20:97,766,179...97,768,892

G

ribosomal protein S11

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA

NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:95,605,692...95,607,874

G

ribosomal protein S12

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS12 mRNA

NCBI chr 1:23,499,943...23,502,234
Ensembl chr 1:21,680,852...21,683,014

G

ribosomal protein S17

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS17 mRNA

NCBI chr 1:135,295,920...135,298,506
Ensembl chr 1:135,295,919...135,298,535
Ensembl chr 8:135,295,919...135,298,535

G

ribosomal protein S19

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of RPS19 mRNA
Chlorine results in increased expression of RPS19 mRNA

NCBI chr 1:89,608,408...89,614,390
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508

G

ribosomal protein S29

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of RPS29 mRNA

NCBI chr 6:87,635,229...87,636,627
Ensembl chr 6:87,635,230...87,636,636
Ensembl chr13:87,635,230...87,636,636

G

ribosomal protein S4, X-linked

increases expression
multiple interactions

Chlorine results in increased expression of RPS4X mRNA
[Ozone co-treated with Chlorine] results in decreased expression of RPS4X mRNA

NCBI chr X:71,338,478...71,342,921
Ensembl chr X:67,298,525...67,303,019
Ensembl chr 4:67,298,525...67,303,019

G

sphingosine-1-phosphate receptor 2

decreases expression
multiple interactions

Chlorine results in decreased expression of S1PR2 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of S1PR2 mRNA

NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:19,502,627...19,523,574

G

sodium voltage-gated channel beta subunit 2

decreases expression
multiple interactions

Chlorine results in decreased expression of SCN2B mRNA
[Ozone co-treated with Chlorine] affects the expression of SCN2B mRNA

NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:45,425,629...45,437,765

G

sodium voltage-gated channel alpha subunit 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SCN4A mRNA

NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545

G

sterol carrier protein 2

decreases expression
multiple interactions

Chlorine results in decreased expression of SCP2 mRNA
[Ozone co-treated with Chlorine] affects the expression of SCP2 mRNA

NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287

G

secretin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA

NCBI chr13:33,680,562...33,744,049
Ensembl chr13:31,127,858...31,180,189

G

selectin P

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SELP mRNA

NCBI chr13:79,009,379...79,044,994
Ensembl chr13:76,476,295...76,511,845

G

serpin family B member 2

increases expression

Chlorine results in increased expression of SERPINB2 mRNA

NCBI chr13:24,051,933...24,065,032
Ensembl chr13:23,541,400...23,550,408

G

serpin family B member 5

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SERPINB5 mRNA

NCBI chr13:23,500,203...23,520,401
Ensembl chr13:22,985,557...23,005,756

G

serpin family E member 1

increases expression
multiple interactions

Chlorine results in increased expression of SERPINE1 mRNA
[Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNA

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657

G

surfactant protein B

affects expression

Chlorine affects the expression of SFTPB protein

NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436

G

surfactant protein D

affects expression
increases expression

Chlorine affects the expression of SFTPD protein
Chlorine results in increased expression of SFTPD protein

PMID:24582687 PMID:36690086

NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927

G

serum/glucocorticoid regulated kinase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of SGK1 mRNA
[Ozone co-treated with Chlorine] results in increased expression of SGK1 mRNA

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:22,980,261...23,098,283

G

sialic acid binding Ig like lectin 1

increases expression

Chlorine results in increased expression of SIGLEC1 mRNA

NCBI chr 3:138,740,171...138,759,966
Ensembl chr 3:118,287,988...118,306,850

G

signal-regulatory protein alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SIRPA mRNA

NCBI chr 3:137,272,932...137,311,279
Ensembl chr 3:116,819,726...116,858,098

G

solute carrier family 10 member 1

decreases expression
multiple interactions

Chlorine results in decreased expression of SLC10A1 mRNA
[Ozone co-treated with Chlorine] affects the expression of SLC10A1 mRNA

NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:100,613,045...100,626,670

G

solute carrier family 14 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC14A2 mRNA

NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968

G

solute carrier family 15 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC15A1 mRNA

NCBI chr15:98,537,641...98,582,544
Ensembl chr15:98,537,641...98,582,545

G

solute carrier family 15 member 4

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC15A4 mRNA

NCBI chr12:34,684,583...34,718,429
Ensembl chr12:29,063,015...29,082,480

G

solute carrier family 16 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNA

NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 17 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA

NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,222,049...41,253,304

G

solute carrier family 18 member A1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC18A1 mRNA

NCBI chr16:25,408,485...25,453,786
Ensembl chr16:20,653,508...20,687,051

G

solute carrier family 1 member 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA

NCBI chr 7:11,492,422...11,521,007
Ensembl chr 7:10,841,837...10,870,449

G

solute carrier family 22 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC22A1 mRNA

NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:48,076,666...48,103,678

G

solute carrier family 22 member 12

multiple interactions

[Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluoro-n-nonanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorodecanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorooctanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of perfluorooctanoic acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]

NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555

G

solute carrier family 22 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA

NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:48,121,061...48,163,268

G

solute carrier family 4 member 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC4A2 mRNA

NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:10,736,425...10,752,965

G

solute carrier family 6 member 12

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNA

NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750

G

solute carrier family 6 member 15

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA

NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239

G

solute carrier family 6 member 9

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC6A9 mRNA

NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:131,374,542...131,408,728

G

solute carrier family 7 member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SLC7A1 mRNA

NCBI chr12:11,664,488...11,740,030
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 9 member A2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SLC9A2 mRNA

NCBI chr 9:42,932,001...43,014,447
Ensembl chr 9:42,931,346...43,014,444

G

solute carrier organic anion transporter family, member 1a4

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] results in increased expression of SLCO1A4 mRNA
Chlorine results in decreased expression of SLCO1A4 mRNA

NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:174,710,004...175,254,573

G

secretory leukocyte peptidase inhibitor

increases expression

Chlorine results in increased expression of SLPI mRNA

NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:153,082,369...153,084,453

G

SMAD family member 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SMAD1 mRNA

NCBI chr19:45,417,430...45,477,962
Ensembl chr19:28,513,131...28,573,651

G

survival of motor neuron 1, telomeric

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of SMN1 mRNA

NCBI chr 2:33,224,115...33,235,162
Ensembl chr 2:31,490,015...31,501,060

G

synaptosome associated protein 25

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SNAP25 mRNA

NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:124,041,898...124,123,760

G

spondin 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA

NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:167,928,972...168,228,226

G

structure specific recognition protein 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SSRP1 mRNA

NCBI chr 3:90,531,024...90,541,132
Ensembl chr 3:70,118,655...70,134,482

G

somatostatin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SST mRNA

NCBI chr11:90,461,546...90,462,823
Ensembl chr11:76,956,896...76,958,173

G

somatostatin receptor 3

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of SSTR3 mRNA

NCBI chr 7:111,973,049...111,980,250
Ensembl chr 7:110,092,575...110,099,769

G

syntaxin 1B

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX1B mRNA

NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280

G

syntaxin 5

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX5A mRNA

NCBI chr 1:215,066,532...215,082,685
Ensembl chr 1:205,637,413...205,653,563

G

syntaxin 6

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of STX6 mRNA

NCBI chr13:69,882,647...69,928,895
Ensembl chr13:67,332,314...67,378,576

G

sulfotransferase family 1B member 1

multiple interactions
decreases expression

[Ozone co-treated with Chlorine] affects the expression of SULT1B1 mRNA
Chlorine results in decreased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,492,708...20,505,483

G

synaptic vesicle glycoprotein 2b

multiple interactions
increases expression

[Ozone co-treated with Chlorine] results in increased expression of SV2B mRNA
Chlorine results in increased expression of SV2B mRNA

NCBI chr 1:138,388,268...138,562,635
Ensembl chr 1:128,978,473...129,152,479

G

synaptophysin

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA

NCBI chr X:17,521,348...17,536,449
Ensembl chr X:14,849,444...14,864,745

G

synaptotagmin 11

decreases expression
multiple interactions

Chlorine results in decreased expression of SYT11 mRNA
[Ozone co-treated with Chlorine] results in decreased expression of SYT11 mRNA

NCBI chr 2:176,503,845...176,530,354
Ensembl chr 2:174,206,191...174,231,964

G

synaptotagmin 2

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYT2 mRNA

NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859

G

synaptotagmin 4

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of SYT4 mRNA

NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332

G

tachykinin receptor 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of TACR2 mRNA

NCBI chr20:30,751,645...30,766,181
Ensembl chr20:30,208,907...30,223,446

G

transporter 2, ATP binding cassette subfamily B member

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TAP2 mRNA

NCBI chr20:4,638,257...4,652,296
Ensembl chr20:4,636,357...4,650,407

G

thromboxane A2 receptor

multiple interactions

[Ozone co-treated with Chlorine] results in increased expression of TBXA2R mRNA

NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:8,383,378...8,388,176

G

transferrin receptor

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor, beta receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of TGFBR1 mRNA

NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:61,653,233...61,710,777

G

TIMP metallopeptidase inhibitor 1

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664

G

thymidine kinase 1

decreases expression
multiple interactions

Chlorine results in decreased expression of TK1 mRNA
[Ozone co-treated with Chlorine] affects the expression of TK1 mRNA

NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,031,521...103,046,920

G

tumor necrosis factor

increases expression

Chlorine results in increased expression of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 1A

increases expression

Chlorine results in increased expression of TNFRSF1A protein

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591

G

DNA topoisomerase II alpha

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TOP2A mRNA

NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874

G

tumor protein p53

multiple interactions
increases expression

Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form]

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524

G

tripeptidyl peptidase 2

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TPP2 mRNA

NCBI chr 9:53,538,788...53,620,253
Ensembl chr 9:46,046,632...46,128,157

G

tubulin, alpha 1A

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of TUBA1A mRNA

NCBI chr 7:131,992,151...131,996,850
Ensembl chr 7:130,081,032...130,196,186

G

thymidylate synthetase

decreases expression
multiple interactions

Chlorine results in decreased expression of TYMS mRNA
[Ozone co-treated with Chlorine] affects the expression of TYMS mRNA

NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536

G

unc-5 netrin receptor B

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of UNC5B mRNA

NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537

G

valosin-containing protein

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of VCP mRNA

NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:57,210,168...57,229,571

G

von Hippel-Lindau tumor suppressor

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VHL mRNA

NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377

G

vasoactive intestinal peptide receptor 1

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VIPR1 mRNA

NCBI chr 8:130,181,219...130,217,098
Ensembl chr 8:121,310,248...121,339,585

G

vasoactive intestinal peptide receptor 2

multiple interactions

[Ozone co-treated with Chlorine] affects the expression of VIPR2 mRNA

NCBI chr 6:143,139,672...143,213,609
Ensembl chr 6:137,001,511...137,070,597

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of YWHAE mRNA

NCBI chr10:61,082,934...61,120,618
Ensembl chr10:60,584,652...60,671,589

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

multiple interactions
increases expression

[Ozone co-treated with Chlorine] affects the expression of YWHAG mRNA
Chlorine results in increased expression of YWHAG mRNA

NCBI chr12:26,381,106...26,409,466
Ensembl chr12:20,744,535...20,772,827

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

multiple interactions

[Ozone co-treated with Chlorine] results in decreased expression of YWHAH mRNA

NCBI chr14:81,920,819...81,930,202
Ensembl chr14:77,696,333...77,705,741

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

increases expression
multiple interactions

Chlorine results in increased expression of YWHAZ mRNA
[Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA

NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:67,940,017...67,963,668

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19899
chemical entity	19897
molecular entity	19896
elemental molecular entity	17207
elemental halogen	9902
elemental chlorine	9025
diatomic chlorine	380
dichloride(.1-)	0
dichlorine	380
dichlorine(.1+)	0
Path 2
Term	Annotations
CHEBI ontology	19899
subatomic particle	19897
composite particle	19897
hadron	19897
baryon	19897
nucleon	19897
atomic nucleus	19897
atom	19897
main group element atom	19836
main group molecular entity	19836
p-block molecular entity	19836
halogen molecular entity	18710
chlorine molecular entity	18488
elemental chlorine	9025
diatomic chlorine	380
dichloride(.1-)	0
dichlorine	380
dichlorine(.1+)	0

paths to the root