CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: diatomic chlorine
Accession: CHEBI:33435
browse the term
Synonyms: related_synonym: Formula=Cl2
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Abcb1b
ATP-binding cassette, sub-family B member 1B
increases expression multiple interactions
ISO
Chlorine results in increased expression of ABCB1B mRNA [Ozone co-treated with Chlorine] results in decreased expression of ABCB1B mRNA
CTD
PMID:18636392
NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
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Abcc1
ATP-binding cassette, sub-family C member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ABCC1 mRNA
CTD
PMID:18636392
NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
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Acadm
acyl-Coenzyme A dehydrogenase, medium chain
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA
CTD
PMID:18636392
NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
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Ache
acetylcholinesterase
multiple interactions
ISO
[[Chlorine co-treated with Diazinon] results in increased abundance of diazoxon] which results in decreased activity of ACHE protein
CTD
PMID:34374289
NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728
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Acot7
acyl-CoA thioesterase 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ACOT7 mRNA
CTD
PMID:18636392
NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312
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Acsl1
acyl-CoA synthetase long-chain family member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ACSL1 mRNA [Ozone co-treated with Chlorine] affects the expression of ACSL1 mRNA
CTD
PMID:18636392
NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
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Acvr1
activin A receptor, type 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ACVR1 mRNA
CTD
PMID:18636392
NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169
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Adcy2
adenylate cyclase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY2 mRNA
CTD
PMID:18636392
NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660
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Adcy3
adenylate cyclase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADCY3 mRNA
CTD
PMID:18636392
NCBI chr12:4,183,397...4,263,525
Ensembl chr12:4,183,103...4,263,525
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Adcy4
adenylate cyclase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADCY4 mRNA
CTD
PMID:18636392
NCBI chr14:56,006,513...56,021,552
Ensembl chr14:56,006,514...56,021,552
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Adcy5
adenylate cyclase 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY5 mRNA
CTD
PMID:18636392
NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108
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Adcy8
adenylate cyclase 8
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY8 mRNA
CTD
PMID:18636392
NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145
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Adgrl1
adhesion G protein-coupled receptor L1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ADGRL1 mRNA [Ozone co-treated with Chlorine] results in increased expression of ADGRL1 mRNA
CTD
PMID:18636392
NCBI chr 8:84,626,598...84,668,583
Ensembl chr 8:84,626,734...84,668,583
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Adora3
adenosine A3 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADORA3 mRNA
CTD
PMID:18636392
NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242
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Adra2c
adrenergic receptor, alpha 2c
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADRA2C mRNA
CTD
PMID:18636392
NCBI chr 5:35,435,910...35,439,107
Ensembl chr 5:35,435,663...35,439,107
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Adrb2
adrenergic receptor, beta 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA
CTD
PMID:18636392
NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
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Ager
advanced glycosylation end product-specific receptor
decreases expression multiple interactions increases expression
ISO EXP
Chlorine results in decreased expression of AGER mRNA [Ozone co-treated with Chlorine] results in increased expression of AGER mRNA Chlorine results in increased expression of AGER protein
CTD
PMID:18636392 PMID:36690086
NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
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Akr1a1
aldo-keto reductase family 1, member A1
increases expression multiple interactions
ISO
Chlorine results in increased expression of AKR1A1 mRNA [Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA
CTD
PMID:18636392
NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877
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Akt1
thymoma viral proto-oncogene 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA
CTD
PMID:18636392
NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
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Akt2
thymoma viral proto-oncogene 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of AKT2 mRNA
CTD
PMID:18636392
NCBI chr 7:27,290,977...27,340,251
Ensembl chr 7:27,290,977...27,340,251
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Aldoc
aldolase C, fructose-bisphosphate
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ALDOC mRNA
CTD
PMID:18636392
NCBI chr11:78,213,899...78,218,607
Ensembl chr11:78,213,794...78,218,607
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Amacr
alpha-methylacyl-CoA racemase
increases expression multiple interactions
ISO
Chlorine results in increased expression of AMACR mRNA [Ozone co-treated with Chlorine] results in increased expression of AMACR mRNA
CTD
PMID:18636392
NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712
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Amph
amphiphysin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of AMPH mRNA
CTD
PMID:18636392
NCBI chr13:19,132,524...19,335,089
Ensembl chr13:19,132,375...19,335,091
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Anxa2
annexin A2
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA2 mRNA Chlorine results in increased expression of ANXA2 mRNA
CTD
PMID:18636392
NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
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Anxa3
annexin A3
increases expression multiple interactions
ISO
Chlorine results in increased expression of ANXA3 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ANXA3 mRNA
CTD
PMID:18636392
NCBI chr 5:96,941,257...96,993,825
Ensembl chr 5:96,941,198...96,993,825
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Anxa4
annexin A4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA4 mRNA
CTD
PMID:18636392
NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566
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Anxa5
annexin A5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA5 mRNA
CTD
PMID:18636392
NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
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Apc
APC, WNT signaling pathway regulator
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of APC mRNA
CTD
PMID:18636392
NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
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Apex1
apurinic/apyrimidinic endonuclease 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNA
CTD
PMID:18636392
NCBI chr14:51,162,406...51,164,645
Ensembl chr14:51,162,425...51,164,596
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Apoa1
apolipoprotein A-I
multiple interactions affects binding
ISO
[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein
CTD
PMID:33861588
NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
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Apod
apolipoprotein D
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of APOD mRNA
CTD
PMID:18636392
NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626
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Aqp1
aquaporin 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of AQP1 mRNA
CTD
PMID:18636392
NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
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Aqp3
aquaporin 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of AQP3 mRNA [Ozone co-treated with Chlorine] affects the expression of AQP3 mRNA
CTD
PMID:18636392
NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
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Arf1
ARF GTPase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF1 mRNA
CTD
PMID:18636392
NCBI chr11:59,102,237...59,119,042
Ensembl chr11:59,102,238...59,119,096
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Arf3
ARF GTPase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA
CTD
PMID:18636392
NCBI chr15:98,635,505...98,660,999
Ensembl chr15:98,634,515...98,661,095
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Arf4
ARF GTPase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF4 mRNA
CTD
PMID:18636392
NCBI chr14:26,359,289...26,377,997
Ensembl chr14:26,359,229...26,386,239
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Arf5
ARF GTPase 5
increases expression multiple interactions
ISO
Chlorine results in increased expression of ARF5 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ARF5 mRNA
CTD
PMID:18636392
NCBI chr 6:28,423,603...28,426,601
Ensembl chr 6:28,423,559...28,426,601
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Arf6
ARF GTPase 6
increases expression multiple interactions
ISO
Chlorine results in increased expression of ARF6 mRNA [Ozone co-treated with Chlorine] affects the expression of ARF6 mRNA
CTD
PMID:18636392
NCBI chr12:69,418,924...69,422,754
Ensembl chr12:69,418,924...69,420,557
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Arg1
arginase, liver
multiple interactions increases expression
ISO EXP
[Ozone co-treated with Chlorine] affects the expression of ARG1 mRNA Chlorine results in increased expression of ARG1 mRNA; Chlorine results in increased expression of ARG1 protein
CTD
PMID:18636392 PMID:24582687 PMID:30189237
NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382
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Arhgap35
Rho GTPase activating protein 35
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ARHGAP35 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ARHGAP35 mRNA
CTD
PMID:18636392
NCBI chr 7:16,228,398...16,349,313
Ensembl chr 7:16,227,644...16,348,918
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Arrb2
arrestin, beta 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ARRB2 mRNA
CTD
PMID:18636392
NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654
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Atf2
activating transcription factor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATF2 mRNA
CTD
PMID:18636392
NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
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Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNA Chlorine results in decreased expression of ATP1A1 mRNA
CTD
PMID:18636392 PMID:24218892
NCBI chr 3:101,483,535...101,512,023
Ensembl chr 3:101,483,535...101,512,000
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Atp2a3
ATPase, Ca++ transporting, ubiquitous
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ATP2A3 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ATP2A3 mRNA
CTD
PMID:18636392
NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870
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Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATP6V0C mRNA
CTD
PMID:18636392
NCBI chr17:24,382,839...24,388,652
Ensembl chr17:24,382,840...24,388,676
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Atp7b
ATPase, copper transporting, beta polypeptide
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ATP7B mRNA
CTD
PMID:18636392
NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321
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Bax
BCL2-associated X protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of BAX mRNA
CTD
PMID:18636392
NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
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Bdkrb2
bradykinin receptor, beta 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of BDKRB2 mRNA
CTD
PMID:18636392
NCBI chr12:105,529,431...105,561,503
Ensembl chr12:105,529,485...105,561,496
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Bmp4
bone morphogenetic protein 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA
CTD
PMID:18636392
NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
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C5ar1
complement component 5a receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of C5AR1 mRNA
CTD
PMID:18636392
NCBI chr 7:15,980,668...15,993,465
Ensembl chr 7:15,980,668...15,993,465
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Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CACNA1A mRNA
CTD
PMID:18636392
NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875
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Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CACNA1B mRNA
CTD
PMID:18636392
NCBI chr 2:24,493,872...24,653,210
Ensembl chr 2:24,493,899...24,653,164
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Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CACNB3 mRNA
CTD
PMID:18636392
NCBI chr15:98,526,317...98,542,410
Ensembl chr15:98,528,721...98,542,410
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Car3
carbonic anhydrase 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CA3 mRNA [Ozone co-treated with Chlorine] affects the expression of CA3 mRNA
CTD
PMID:18636392
NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583
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Cartpt
CART prepropeptide
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CARTPT mRNA [Ozone co-treated with Chlorine] affects the expression of CARTPT mRNA
CTD
PMID:18636392
NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
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Casp3
caspase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CASP3 mRNA
CTD
PMID:18636392
NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
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Casr
calcium-sensing receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CASR mRNA
CTD
PMID:18636392
NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503
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Cast
calpastatin
increases expression multiple interactions
ISO
Chlorine results in increased expression of CAST mRNA [Ozone co-treated with Chlorine] affects the expression of CAST mRNA
CTD
PMID:18636392
NCBI chr13:74,840,485...74,956,993
Ensembl chr13:74,840,487...74,956,929
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Cat
catalase
increases expression multiple interactions
ISO EXP
Chlorine results in increased expression of CAT protein Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]
CTD
PMID:35065218 PMID:36690086
NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
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Cckbr
cholecystokinin B receptor
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CCKBR mRNA [Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA
CTD
PMID:18636392
NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105
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Ccl11
C-C motif chemokine ligand 11
increases expression
EXP
Chlorine results in increased expression of CCL11 protein
CTD
PMID:23146759
NCBI chr11:81,948,658...81,953,781
Ensembl chr11:81,948,649...81,953,781
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Ccl12
C-C motif chemokine ligand 12
increases expression
EXP
Chlorine results in increased expression of CCL12 mRNA
CTD
PMID:30189237
NCBI chr11:81,992,671...81,994,225
Ensembl chr11:81,992,671...81,994,226
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Ccl2
C-C motif chemokine ligand 2
increases expression decreases secretion multiple interactions
EXP ISO
Chlorine results in increased expression of CCL2 mRNA; Chlorine results in increased expression of CCL2 protein Chlorine results in decreased secretion of CCL2 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]
CTD
PMID:23146759 PMID:24582687 PMID:30189237 PMID:35065218
NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
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Ccl20
C-C motif chemokine ligand 20
increases expression
EXP
Chlorine results in increased expression of CCL20 mRNA
CTD
PMID:24582687
NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888
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Ccl3
C-C motif chemokine ligand 3
increases expression
EXP
Chlorine results in increased expression of CCL3 protein
CTD
PMID:23146759
NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
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Ccl5
C-C motif chemokine ligand 5
increases expression multiple interactions
EXP
Chlorine results in increased expression of CCL5 protein [Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA
CTD
PMID:23146759 PMID:31066272
NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
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Ccl6
C-C motif chemokine ligand 6
increases expression
EXP
Chlorine results in increased expression of CCL6 mRNA
CTD
PMID:30189237
NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913
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Ccl7
C-C motif chemokine ligand 7
increases expression
EXP
Chlorine results in increased expression of CCL7 mRNA
CTD
PMID:30189237
NCBI chr11:81,936,538...81,938,351
Ensembl chr11:81,936,538...81,938,351
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Ccl8
C-C motif chemokine ligand 8
increases expression
EXP
Chlorine results in increased expression of CCL8 mRNA
CTD
PMID:30189237
NCBI chr11:82,006,011...82,007,625
Ensembl chr11:82,006,011...82,007,625
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Ccnc
cyclin C
increases expression multiple interactions
ISO
Chlorine results in increased expression of CCNC mRNA [Ozone co-treated with Chlorine] results in decreased expression of CCNC mRNA
CTD
PMID:18636392
NCBI chr 4:21,727,705...21,759,917
Ensembl chr 4:21,727,701...21,759,922
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Ccnd1
cyclin D1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCND1 mRNA
CTD
PMID:18636392
NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
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Ccnd3
cyclin D3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA
CTD
PMID:18636392
NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
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Ccng1
cyclin G1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCNG1 mRNA
CTD
PMID:18636392
NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
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Cd4
CD4 antigen
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CD4 mRNA [Ozone co-treated with Chlorine] affects the expression of CD4 mRNA
CTD
PMID:18636392
NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184
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Cd44
CD44 antigen
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA
CTD
PMID:18636392
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
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Cd9
CD9 antigen
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CD9 mRNA
CTD
PMID:18636392
NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754
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Cdc25b
cell division cycle 25B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CDC25B mRNA
CTD
PMID:18636392
NCBI chr 2:131,028,356...131,040,431
Ensembl chr 2:131,028,869...131,040,417
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Cdh22
cadherin 22
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA
CTD
PMID:18636392
NCBI chr 2:164,953,421...165,076,892
Ensembl chr 2:164,953,427...165,076,773
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Cdk4
cyclin dependent kinase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA
CTD
PMID:18636392
NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
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Cdkn1a
cyclin dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
Chlorine results in increased expression of CDKN1A mRNA [Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA
CTD
PMID:18636392
NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
G
Cdkn2b
cyclin dependent kinase inhibitor 2B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CDKN2B mRNA
CTD
PMID:18636392
NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
G
Cfl1
cofilin 1, non-muscle
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CFL1 mRNA
CTD
PMID:18636392
NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
G
Cftr
cystic fibrosis transmembrane conductance regulator
multiple interactions increases transport
ISO
CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]] CFTR protein results in increased transport of Chlorine
CTD
PMID:12612912 PMID:21765217
NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
G
Chil3
chitinase-like 3
increases expression
EXP
Chlorine results in increased expression of CHIL3 mRNA
CTD
PMID:30189237
NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880
G
Chrna1
cholinergic receptor nicotinic alpha 1 subunit
increases expression multiple interactions
ISO
Chlorine results in increased expression of CHRNA1 mRNA [Ozone co-treated with Chlorine] results in increased expression of CHRNA1 mRNA
CTD
PMID:18636392
NCBI chr 2:73,393,625...73,410,682
Ensembl chr 2:73,393,559...73,410,682
G
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CHRNA4 mRNA
CTD
PMID:18636392
NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339
G
Chrnb1
cholinergic receptor nicotinic beta 1 subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CHRNB1 mRNA
CTD
PMID:18636392
NCBI chr11:69,674,862...69,686,742
Ensembl chr11:69,674,862...69,686,769
G
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
affects expression multiple interactions
ISO
Chlorine affects the expression of CKMT1 mRNA [Ozone co-treated with Chlorine] results in increased expression of CKMT1 mRNA
CTD
PMID:18636392
NCBI chr 2:121,188,257...121,194,218
Ensembl chr 2:121,188,195...121,194,218
G
Clec4d
C-type lectin domain family 4, member d
increases expression
EXP
Chlorine results in increased expression of CLEC4D mRNA
CTD
PMID:30189237
NCBI chr 6:123,239,066...123,252,227
Ensembl chr 6:123,239,070...123,252,224
G
Clu
clusterin
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CLU mRNA Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein]
CTD
PMID:18636392 PMID:35065218
NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996
G
Cmklr1
chemerin chemokine-like receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA
CTD
PMID:18636392
NCBI chr 5:113,750,415...113,792,971
Ensembl chr 5:113,750,415...113,788,487
G
Cnn3
calponin 3, acidic
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CNN3 mRNA
CTD
PMID:18636392
NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856
G
Cnr1
cannabinoid receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CNR1 mRNA
CTD
PMID:18636392
NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
G
Cpd
carboxypeptidase D
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CPD mRNA
CTD
PMID:18636392
NCBI chr11:76,668,034...76,737,834
Ensembl chr11:76,669,250...76,737,844
G
Cpt1b
carnitine palmitoyltransferase 1b, muscle
increases expression multiple interactions
ISO
Chlorine results in increased expression of CPT1B mRNA [Ozone co-treated with Chlorine] results in decreased expression of CPT1B mRNA
CTD
PMID:18636392
NCBI chr15:89,300,608...89,310,065
Ensembl chr15:89,300,608...89,310,066
G
Crhr2
corticotropin releasing hormone receptor 2
increases expression multiple interactions
ISO
Chlorine results in increased expression of CRHR2 mRNA [Ozone co-treated with Chlorine] affects the expression of CRHR2 mRNA
CTD
PMID:18636392
NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001
G
Crk
v-crk avian sarcoma virus CT10 oncogene homolog
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CRK mRNA
CTD
PMID:18636392
NCBI chr11:75,570,020...75,599,254
Ensembl chr11:75,570,085...75,597,734
G
Csf1r
colony stimulating factor 1 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CSF1R mRNA
CTD
PMID:18636392
NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221
G
Csf2
colony stimulating factor 2 (granulocyte-macrophage)
increases expression
EXP
Chlorine results in increased expression of CSF2 protein
CTD
PMID:23146759
NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
G
Csf3
colony stimulating factor 3 (granulocyte)
increases expression multiple interactions
ISO EXP
Chlorine results in increased expression of CSF3 mRNA [Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA Chlorine results in increased expression of CSF3 protein
CTD
PMID:18636392 PMID:23146759
NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
G
Csnk1g1
casein kinase 1, gamma 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of CSNK1G1 mRNA Chlorine results in decreased expression of CSNK1G1 mRNA
CTD
PMID:18636392
NCBI chr 9:65,816,235...65,952,297
Ensembl chr 9:65,816,206...65,952,297
G
Csrp3
cysteine and glycine-rich protein 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of CSRP3 mRNA [Ozone co-treated with Chlorine] results in increased expression of CSRP3 mRNA
CTD
PMID:18636392
NCBI chr 7:48,480,146...48,497,799
Ensembl chr 7:48,480,146...48,497,781
G
Ctsb
cathepsin B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNA
CTD
PMID:18636392
NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
G
Ctsl
cathepsin L
increases expression multiple interactions
ISO
Chlorine results in increased expression of CTSL mRNA [Ozone co-treated with Chlorine] results in decreased expression of CTSL mRNA
CTD
PMID:18636392
NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
G
Cxcl10
C-X-C motif chemokine ligand 10
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CXCL10 mRNA [Ozone co-treated with Chlorine] results in increased expression of CXCL10 mRNA
CTD
PMID:18636392
NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
G
Cxcl15
C-X-C motif chemokine ligand 15
decreases secretion multiple interactions
ISO
Chlorine results in decreased secretion of CXCL8 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CXCL8 protein]
CTD
PMID:35065218
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
G
Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions increases expression
EXP
triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein] Chlorine results in increased expression of CXCL1 mRNA; Chlorine results in increased expression of CXCL1 protein
CTD
PMID:20348278 PMID:20819911 PMID:23146759 PMID:24582687
NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459
G
Cxcr4
C-X-C motif chemokine receptor 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CXCR4 mRNA
CTD
PMID:18636392
NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
G
Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CYP11A1 mRNA
CTD
PMID:18636392
NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA Chlorine results in increased expression of CYP19A1 mRNA
CTD
PMID:18636392
NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
G
Cyp2c52-ps
cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CYP2C mRNA [Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA
CTD
PMID:18636392
NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
G
Ddc
dopa decarboxylase
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of DDC mRNA Chlorine results in decreased expression of DDC mRNA
CTD
PMID:18636392
NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144
G
Ddit3
DNA-damage inducible transcript 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of DDIT3 mRNA
CTD
PMID:18636392
NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157 Ensembl chr10:127,126,643...127,132,157
G
Dpp4
dipeptidylpeptidase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of DPP4 mRNA
CTD
PMID:18636392
NCBI chr 2:62,160,417...62,242,635
Ensembl chr 2:62,160,417...62,242,575
G
Dpp6
dipeptidylpeptidase 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of DPP6 mRNA
CTD
PMID:18636392
NCBI chr 5:27,022,355...27,932,498
Ensembl chr 5:27,022,201...27,932,503
G
Drd1
dopamine receptor D1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of DRD1 mRNA
CTD
PMID:18636392
NCBI chr13:54,205,202...54,209,677
Ensembl chr13:54,205,202...54,209,724
G
Eef2
eukaryotic translation elongation factor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA
CTD
PMID:18636392
NCBI chr10:81,012,465...81,018,343
Ensembl chr10:81,012,465...81,018,332
G
Egr1
early growth response 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of EGR1 mRNA
CTD
PMID:18636392
NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
G
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA
CTD
PMID:18636392
NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
G
Eif5
eukaryotic translation initiation factor 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EIF5 mRNA
CTD
PMID:18636392
NCBI chr12:111,504,535...111,513,187
Ensembl chr12:111,504,450...111,513,186
G
F2
coagulation factor II
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of F2 mRNA [Ozone co-treated with Chlorine] affects the expression of F2 mRNA
CTD
PMID:18636392
NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
G
Faah
fatty acid amide hydrolase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of FAAH mRNA
CTD
PMID:18636392
NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123
G
Fabp1
fatty acid binding protein 1, liver
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FABP1 mRNA [Ozone co-treated with Chlorine] affects the expression of FABP1 mRNA
CTD
PMID:18636392
NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
G
Fabp2
fatty acid binding protein 2, intestinal
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of FABP2 mRNA
CTD
PMID:18636392
NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
G
Fabp4
fatty acid binding protein 4, adipocyte
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of FABP4 mRNA
CTD
PMID:18636392
NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
G
Fabp5
fatty acid binding protein 5, epidermal
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA
CTD
PMID:18636392
NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FAS mRNA
CTD
PMID:18636392
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
G
Fgf10
fibroblast growth factor 10
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FGF10 mRNA [Ozone co-treated with Chlorine] affects the expression of FGF10 mRNA
CTD
PMID:18636392
NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651
G
Fgf2
fibroblast growth factor 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of FGF2 mRNA Chlorine results in decreased expression of FGF2 mRNA
CTD
PMID:18636392
NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of FGR mRNA
CTD
PMID:18636392
NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221
G
Fos
FBJ osteosarcoma oncogene
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FOS mRNA [Ozone co-treated with Chlorine] affects the expression of FOS mRNA
CTD
PMID:18636392
NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
G
Fosl1
fos-like antigen 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FOSL1 mRNA
CTD
PMID:18636392
NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
G
Gabbr1
gamma-aminobutyric acid type B receptor subunit 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GABBR1 mRNA [Ozone co-treated with Chlorine] results in increased expression of GABBR1 mRNA
CTD
PMID:18636392
NCBI chr17:37,356,888...37,385,197
Ensembl chr17:37,356,858...37,385,959
G
Galr1
galanin receptor 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GALR1 mRNA [Ozone co-treated with Chlorine] results in increased expression of GALR1 mRNA
CTD
PMID:18636392
NCBI chr18:82,410,621...82,424,902
Ensembl chr18:82,410,505...82,424,902
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA
CTD
PMID:18636392
NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430
G
Gcgr
glucagon receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GCGR mRNA
CTD
PMID:18636392
NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812
G
Gclm
glutamate-cysteine ligase, modifier subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA
CTD
PMID:18636392
NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
G
Gdi1
GDP dissociation inhibitor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GDI1 mRNA
CTD
PMID:18636392
NCBI chr X:73,348,618...73,355,473
Ensembl chr X:73,348,604...73,355,468
G
Gdi2
GDP dissociation inhibitor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GDI2 mRNA
CTD
PMID:18636392
NCBI chr13:3,588,075...3,616,261
Ensembl chr13:3,588,063...3,617,871
G
Ghr
growth hormone receptor
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GHR mRNA Chlorine results in decreased expression of GHR mRNA
CTD
PMID:18636392
NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974
G
Gipr
gastric inhibitory polypeptide receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GIPR mRNA
CTD
PMID:18636392
NCBI chr 7:18,889,988...18,904,173
Ensembl chr 7:18,889,986...18,900,052
G
Gmfb
glia maturation factor, beta
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA
CTD
PMID:18636392
NCBI chr14:47,045,606...47,059,711
Ensembl chr14:47,045,606...47,059,699
G
Gnai1
G protein subunit alpha i1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAI1 mRNA
CTD
PMID:18636392
NCBI chr 5:18,470,133...18,565,411
Ensembl chr 5:18,470,133...18,565,353
G
Gnai2
G protein subunit alpha i2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA
CTD
PMID:18636392
NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
G
Gnao1
guanine nucleotide binding protein, alpha O
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GNAO1 mRNA [Ozone co-treated with Chlorine] affects the expression of GNAO1 mRNA
CTD
PMID:18636392
NCBI chr 8:94,537,213...94,696,016
Ensembl chr 8:94,536,594...94,696,016
G
Gnas
GNAS complex locus
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA
CTD
PMID:18636392
NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537
G
Gnaz
guanine nucleotide binding protein, alpha z subunit
increases expression multiple interactions
ISO
Chlorine results in increased expression of GNAZ mRNA [Ozone co-treated with Chlorine] results in increased expression of GNAZ mRNA
CTD
PMID:18636392
NCBI chr10:74,803,009...74,852,739
Ensembl chr10:74,803,009...74,852,739
G
Gnb1
guanine nucleotide binding protein (G protein), beta 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNB1 mRNA
CTD
PMID:18636392
NCBI chr 4:155,575,514...155,643,726
Ensembl chr 4:155,575,818...155,643,726
G
Gpx3
glutathione peroxidase 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of GPX3 mRNA [Ozone co-treated with Chlorine] affects the expression of GPX3 mRNA
CTD
PMID:18636392
NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203
G
Gpx5
glutathione peroxidase 5
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GPX5 mRNA Chlorine results in increased expression of GPX5 mRNA
CTD
PMID:18636392
NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901
G
Grk3
G protein-coupled receptor kinase 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of GRK3 mRNA [Ozone co-treated with Chlorine] results in increased expression of GRK3 mRNA
CTD
PMID:18636392
NCBI chr 5:113,058,344...113,163,518
Ensembl chr 5:113,058,348...113,163,657
G
Gsr
glutathione reductase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GSR mRNA
CTD
PMID:18636392
NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
G
Gss
glutathione synthetase
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA Chlorine results in increased expression of GSS mRNA
CTD
PMID:18636392
NCBI chr 2:155,405,101...155,434,730
Ensembl chr 2:155,405,101...155,434,730
G
Gsta4
glutathione S-transferase, alpha 4
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GSTA4 mRNA Chlorine results in decreased expression of GSTA4 mRNA
CTD
PMID:18636392
NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631
G
Gstk1
glutathione S-transferase kappa 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of GSTK1 mRNA [Ozone co-treated with Chlorine] affects the expression of GSTK1 mRNA
CTD
PMID:18636392
NCBI chr 6:42,222,869...42,227,375
Ensembl chr 6:42,222,869...42,227,381
G
Gstm2
glutathione S-transferase, mu 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNA Chlorine results in decreased expression of GSTM2 mRNA
CTD
PMID:18636392
NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769
G
Gucy2e
guanylate cyclase 2e
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GUCY2D mRNA
CTD
PMID:18636392
NCBI chr11:69,108,943...69,128,083
Ensembl chr11:69,108,943...69,127,862
G
H2ax
H2A.X variant histone
increases expression
EXP
Chlorine results in increased expression of H2AX protein
CTD
PMID:36690086
NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
G
Hmgcs2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of HMGCS2 mRNA [Ozone co-treated with Chlorine] affects the expression of HMGCS2 mRNA
CTD
PMID:18636392
NCBI chr 3:98,187,747...98,218,054
Ensembl chr 3:98,187,751...98,218,054
G
Hmox1
heme oxygenase 1
increases expression
EXP
Chlorine results in increased expression of HMOX1 protein
CTD
PMID:36690086
NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
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Hmox2
heme oxygenase 2
increases expression
ISO
Chlorine results in increased expression of HMOX2 protein
CTD
PMID:35065218
NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
G
Hpcal4
hippocalcin-like 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HPCAL4 mRNA
CTD
PMID:18636392
NCBI chr 4:123,077,297...123,088,492
Ensembl chr 4:123,077,020...123,088,494
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of HPRT1 mRNA Chlorine results in increased expression of HPRT1 mRNA
CTD
PMID:18636392
NCBI chr X:52,076,955...52,110,537
Ensembl chr X:52,077,014...52,110,536
G
Hras
Harvey rat sarcoma virus oncogene
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of HRAS mRNA
CTD
PMID:18636392
NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
G
Hsd3b1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of HSD3B1 mRNA [Ozone co-treated with Chlorine] affects the expression of HSD3B1 mRNA
CTD
PMID:18636392
NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110
G
Hspa5
heat shock protein 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA
CTD
PMID:18636392
NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
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Hspd1
heat shock protein 1 (chaperonin)
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of HSPD1 mRNA Chlorine results in increased expression of HSPD1 protein Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]
CTD
PMID:18636392 PMID:35065218
NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
G
Htr1f
5-hydroxytryptamine (serotonin) receptor 1F
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HTR1F mRNA
CTD
PMID:18636392
NCBI chr16:64,745,092...64,926,147
Ensembl chr16:64,745,092...64,926,217
G
Htr6
5-hydroxytryptamine (serotonin) receptor 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HTR6 mRNA
CTD
PMID:18636392
NCBI chr 4:138,787,017...138,802,881
Ensembl chr 4:138,788,419...138,802,881
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Htt
huntingtin
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of HTT mRNA
CTD
PMID:18636392
NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878
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Id2
inhibitor of DNA binding 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of ID2 mRNA Chlorine results in decreased expression of ID2 mRNA
CTD
PMID:18636392
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
G
Ifi204
interferon activated gene 204
increases expression
EXP
Chlorine results in increased expression of IFI204 mRNA
CTD
PMID:30189237
NCBI chr 1:173,574,859...173,594,606
Ensembl chr 1:173,574,859...173,594,509
G
Ifng
interferon gamma
multiple interactions increases expression
ISO EXP
[Ozone co-treated with Chlorine] affects the expression of IFNG mRNA Chlorine results in increased expression of IFNG protein
CTD
PMID:18636392 PMID:23146759
NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
G
Igfals
insulin-like growth factor binding protein, acid labile subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNA
CTD
PMID:18636392
NCBI chr17:25,096,818...25,100,985
Ensembl chr17:25,084,971...25,100,984
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Igfbp3
insulin-like growth factor binding protein 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of IGFBP3 mRNA [Ozone co-treated with Chlorine] affects the expression of IGFBP3 mRNA
CTD
PMID:18636392
NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
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Il12a
interleukin 12a
increases expression
EXP
Chlorine results in increased expression of IL12A protein
CTD
PMID:23146759
NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
G
Il12b
interleukin 12b
increases expression
EXP
Chlorine results in increased expression of IL12B protein
CTD
PMID:23146759
NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
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Il13
interleukin 13
increases expression
EXP
Chlorine results in increased expression of IL13 protein
CTD
PMID:23146759
NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
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Il18
interleukin 18
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA
CTD
PMID:18636392
NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
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Il1b
interleukin 1 beta
multiple interactions increases expression affects expression
ISO EXP
[Ozone co-treated with Chlorine] results in increased expression of IL1B mRNA Chlorine results in increased expression of IL1B protein Chlorine affects the expression of IL1B mRNA [Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein
CTD
PMID:18636392 PMID:23146759 PMID:24582687 PMID:31066272
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
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Il1rl1
interleukin 1 receptor-like 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of IL1RL1 mRNA Chlorine results in decreased expression of IL1RL1 mRNA
CTD
PMID:18636392
NCBI chr 1:40,444,105...40,504,575
Ensembl chr 1:40,468,730...40,504,575
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Il4ra
interleukin 4 receptor, alpha
increases expression
EXP
Chlorine results in increased expression of IL4RA mRNA
CTD
PMID:30189237
NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
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Il6
interleukin 6
increases expression decreases secretion multiple interactions
EXP ISO
Chlorine results in increased expression of IL6 mRNA; Chlorine results in increased expression of IL6 protein Chlorine results in decreased secretion of IL6 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]
CTD
PMID:23146759 PMID:30189237 PMID:35065218
NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
G
Inhba
inhibin beta-A
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of INHBA mRNA
CTD
PMID:18636392
NCBI chr13:16,178,841...16,206,194
Ensembl chr13:16,186,436...16,206,206
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Insrr
insulin receptor-related receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of INSRR mRNA
CTD
PMID:18636392
NCBI chr 3:87,704,215...87,723,408
Ensembl chr 3:87,704,258...87,723,408
G
Itga1
integrin alpha 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ITGA1 mRNA
CTD
PMID:18636392
NCBI chr13:115,094,615...115,238,500
Ensembl chr13:115,089,632...115,238,500
G
Itgb1
integrin beta 1 (fibronectin receptor beta)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ITGB1 mRNA
CTD
PMID:18636392
NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
G
Itpr3
inositol 1,4,5-triphosphate receptor 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ITPR3 mRNA
CTD
PMID:18636392
NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197
G
Jun
jun proto-oncogene
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of JUN mRNA [Ozone co-treated with Chlorine] affects the expression of JUN mRNA
CTD
PMID:18636392
NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
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Jup
junction plakoglobin
increases expression multiple interactions
ISO
Chlorine results in increased expression of JUP mRNA [Ozone co-treated with Chlorine] results in decreased expression of JUP mRNA
CTD
PMID:18636392
NCBI chr11:100,259,682...100,288,639
Ensembl chr11:100,259,784...100,288,589
G
Kcna4
potassium voltage-gated channel, shaker-related subfamily, member 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNA4 mRNA
CTD
PMID:18636392
NCBI chr 2:107,120,934...107,157,149
Ensembl chr 2:107,120,984...107,128,847
G
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
affects expression multiple interactions
ISO
Chlorine affects the expression of KCNB1 mRNA [Ozone co-treated with Chlorine] affects the expression of KCNB1 mRNA
CTD
PMID:18636392
NCBI chr 2:166,937,889...167,032,088
Ensembl chr 2:166,937,889...167,032,075
G
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of KCND2 mRNA
CTD
PMID:18636392
NCBI chr 6:21,212,101...21,729,804
Ensembl chr 6:21,215,502...21,729,804
G
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of KCNJ4 mRNA [Ozone co-treated with Chlorine] results in decreased expression of KCNJ4 mRNA
CTD
PMID:18636392
NCBI chr15:79,364,427...79,396,712
Ensembl chr15:79,367,915...79,389,442
G
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNJ5 mRNA
CTD
PMID:18636392
NCBI chr 9:32,226,002...32,255,640
Ensembl chr 9:32,226,003...32,255,646
G
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNJ8 mRNA
CTD
PMID:18636392
NCBI chr 6:142,510,563...142,517,340
Ensembl chr 6:142,510,563...142,517,340
G
Klkb1
kallikrein B, plasma 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of KLKB1 mRNA
CTD
PMID:18636392
NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896
G
Kras
Kirsten rat sarcoma viral oncogene homolog
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNA
CTD
PMID:18636392
NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
G
Lcat
lecithin cholesterol acyltransferase
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of LCAT mRNA Chlorine results in decreased expression of LCAT mRNA [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein
CTD
PMID:18636392 PMID:33861588
NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
G
Limk1
LIM domain kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of LIMK1 mRNA
CTD
PMID:18636392
NCBI chr 5:134,684,893...134,718,713
Ensembl chr 5:134,684,893...134,717,452
G
Lipc
lipase, hepatic
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of LIPC mRNA [Ozone co-treated with Chlorine] results in increased expression of LIPC mRNA
CTD
PMID:18636392
NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
G
Lipe
lipase, hormone sensitive
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of LIPE mRNA
CTD
PMID:18636392
NCBI chr 7:25,078,952...25,097,911
Ensembl chr 7:25,078,952...25,098,135
G
Lyn
LYN proto-oncogene, Src family tyrosine kinase
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of LYN mRNA Chlorine results in increased expression of LYN mRNA
CTD
PMID:18636392
NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
G
Mal
myelin and lymphocyte protein, T cell differentiation protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MAL mRNA
CTD
PMID:18636392
NCBI chr 2:127,475,146...127,498,615
Ensembl chr 2:127,475,146...127,498,615
G
Map2k1
mitogen-activated protein kinase kinase 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAP2K1 mRNA Chlorine results in increased expression of MAP2K1 mRNA
CTD
PMID:18636392
NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
G
Mapk1
mitogen-activated protein kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAPK1 mRNA
CTD
PMID:18636392
NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
G
Mapk3
mitogen-activated protein kinase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAPK3 mRNA
CTD
PMID:18636392
NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
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Max
Max protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA
CTD
PMID:18636392
NCBI chr12:76,984,045...77,009,123
Ensembl chr12:76,984,043...77,008,975
G
Mc4r
melanocortin 4 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MC4R mRNA
CTD
PMID:18636392
NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577
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Mecp2
methyl CpG binding protein 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MECP2 mRNA
CTD
PMID:18636392
NCBI chr X:73,070,198...73,129,296
Ensembl chr X:73,070,198...73,129,296
G
Meox2
mesenchyme homeobox 2
affects expression multiple interactions
ISO
Chlorine affects the expression of MEOX2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of MEOX2 mRNA
CTD
PMID:18636392
NCBI chr12:37,158,539...37,229,533
Ensembl chr12:37,158,539...37,229,533
G
Mgmt
O-6-methylguanine-DNA methyltransferase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNA
CTD
PMID:18636392
NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
G
Mgst1
microsomal glutathione S-transferase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of MGST1 mRNA [Ozone co-treated with Chlorine] affects the expression of MGST1 mRNA
CTD
PMID:18636392
NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753
G
Mmp14
matrix metallopeptidase 14 (membrane-inserted)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MMP14 mRNA
CTD
PMID:18636392
NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
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Mmp9
matrix metallopeptidase 9
multiple interactions decreases secretion increases expression
ISO EXP
Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein] Chlorine results in increased expression of MMP9 protein
CTD
PMID:35065218 PMID:36690086
NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
G
Mpo
myeloperoxidase
multiple interactions
ISO
[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein; MPO protein promotes the reaction [chlorodimedone binds to Chlorine]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]]
CTD
PMID:31288001 PMID:33861588
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Mrc1
mannose receptor, C type 1
increases expression
EXP
Chlorine results in increased expression of MRC1 mRNA
CTD
PMID:30189237
NCBI chr 2:14,234,225...14,336,834
Ensembl chr 2:14,234,203...14,336,868
G
Mrgprf
MAS-related GPR, member F
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MRGPRF mRNA
CTD
PMID:18636392
NCBI chr 7:144,854,646...144,863,294
Ensembl chr 7:144,854,565...144,863,294
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Mtnr1a
melatonin receptor 1A
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of MTNR1A mRNA [Ozone co-treated with Chlorine] results in increased expression of MTNR1A mRNA
CTD
PMID:18636392
NCBI chr 8:45,522,144...45,542,270
Ensembl chr 8:45,522,174...45,541,543
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Mvp
major vault protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MVP mRNA
CTD
PMID:18636392
NCBI chr 7:126,586,036...126,613,729
Ensembl chr 7:126,586,032...126,613,793
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Myo1b
myosin IB
increases expression multiple interactions
ISO
Chlorine results in increased expression of MYO1B mRNA [Ozone co-treated with Chlorine] affects the expression of MYO1B mRNA
CTD
PMID:18636392
NCBI chr 1:51,788,915...51,955,143
Ensembl chr 1:51,788,924...51,955,230
G
Nell1
NEL-like 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NELL1 mRNA
CTD
PMID:18636392
NCBI chr 7:49,625,098...50,513,037
Ensembl chr 7:49,624,612...50,516,356
G
Nell2
NEL-like 2
increases expression multiple interactions
ISO
Chlorine results in increased expression of NELL2 mRNA [Ozone co-treated with Chlorine] results in increased expression of NELL2 mRNA
CTD
PMID:18636392
NCBI chr15:95,117,321...95,426,677
Ensembl chr15:94,973,111...95,426,440
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of NFKBIA mRNA Chlorine results in decreased expression of NFKBIA mRNA
CTD
PMID:18636392
NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
G
Ngb
neuroglobin
affects abundance
ISO
NGB protein affects the abundance of Chlorine
CTD
PMID:19154338
NCBI chr12:87,144,305...87,149,313
Ensembl chr12:87,144,305...87,149,313
G
Nme2
NME/NM23 nucleoside diphosphate kinase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NME2 mRNA
CTD
PMID:18636392
NCBI chr11:93,840,640...93,847,082
Ensembl chr11:93,840,640...93,847,085
G
Nos1
nitric oxide synthase 1, neuronal
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NOS1 mRNA
CTD
PMID:18636392
NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905
G
Nos2
nitric oxide synthase 2, inducible
increases expression
ISO
Chlorine results in increased expression of NOS2 mRNA
CTD
PMID:21131444
NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
G
Nos3
nitric oxide synthase 3, endothelial cell
decreases activity decreases expression
ISO
Chlorine results in decreased activity of NOS3 protein Chlorine results in decreased expression of NOS3 protein
CTD
PMID:21131444
NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
G
Nppc
natriuretic peptide type C
multiple interactions affects expression
ISO
[Ozone co-treated with Chlorine] affects the expression of NPPC mRNA Chlorine affects the expression of NPPC mRNA
CTD
PMID:18636392
NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293
G
Nptxr
neuronal pentraxin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA
CTD
PMID:18636392
NCBI chr15:79,670,552...79,688,910
Ensembl chr15:79,670,552...79,688,967
G
Nr2c2
nuclear receptor subfamily 2, group C, member 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NR2C2 mRNA [Ozone co-treated with Chlorine] affects the expression of NR2C2 mRNA
CTD
PMID:18636392
NCBI chr 6:92,068,426...92,150,039
Ensembl chr 6:92,068,371...92,151,275
G
Nr2f1
nuclear receptor subfamily 2, group F, member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA
CTD
PMID:18636392
NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876
G
Nr3c2
nuclear receptor subfamily 3, group C, member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA
CTD
PMID:18636392
NCBI chr 8:77,626,422...77,971,641
Ensembl chr 8:77,626,070...77,971,641
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NR4A1 mRNA [Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA
CTD
PMID:18636392
NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA
CTD
PMID:18636392
NCBI chr 4:48,045,098...48,086,446
Ensembl chr 4:48,045,153...48,086,447
G
Nrp2
neuropilin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NRP2 mRNA
CTD
PMID:18636392
NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854
G
Nrxn1
neurexin I
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NRXN1 mRNA
CTD
PMID:18636392
NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499
G
Nrxn2
neurexin II
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NRXN2 mRNA
CTD
PMID:18636392
NCBI chr19:6,468,786...6,583,247
Ensembl chr19:6,468,761...6,594,199
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Ntrk1
neurotrophic tyrosine kinase, receptor, type 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NTRK1 mRNA
CTD
PMID:18636392
NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469
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Ntsr2
neurotensin receptor 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NTSR2 mRNA [Ozone co-treated with Chlorine] affects the expression of NTSR2 mRNA
CTD
PMID:18636392
NCBI chr12:16,703,477...16,710,223
Ensembl chr12:16,703,383...16,710,228
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Odc1
ornithine decarboxylase, structural 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ODC1 mRNA
CTD
PMID:18636392
NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
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Oprk1
opioid receptor, kappa 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNA Chlorine results in decreased expression of OPRK1 mRNA
CTD
PMID:18636392
NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354
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Pak1
p21 (RAC1) activated kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PAK1 mRNA
CTD
PMID:18636392
NCBI chr 7:97,437,748...97,561,588
Ensembl chr 7:97,437,748...97,561,588
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Pcna
proliferating cell nuclear antigen
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PCNA mRNA
CTD
PMID:18636392
NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
G
Pcsk7
proprotein convertase subtilisin/kexin type 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PCSK7 mRNA
CTD
PMID:18636392
NCBI chr 9:45,817,745...45,843,405
Ensembl chr 9:45,817,795...45,841,024
G
Pdap1
PDGFA associated protein 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PDAP1 mRNA
CTD
PMID:18636392
NCBI chr 5:145,065,580...145,076,835
Ensembl chr 5:145,065,579...145,077,048
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Pde4d
phosphodiesterase 4D, cAMP specific
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PDE4D mRNA
CTD
PMID:18636392
NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
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Pdgfrb
platelet derived growth factor receptor, beta polypeptide
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNA
CTD
PMID:18636392
NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
G
Pdia4
protein disulfide isomerase associated 4
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA Chlorine results in increased expression of PDIA4 mRNA
CTD
PMID:18636392
NCBI chr 6:47,773,075...47,790,446
Ensembl chr 6:47,773,075...47,790,364
G
Pdlim1
PDZ and LIM domain 1 (elfin)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PDLIM1 mRNA
CTD
PMID:18636392
NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286
G
Pfkfb4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA
CTD
PMID:18636392
NCBI chr 9:108,817,336...108,861,302
Ensembl chr 9:108,820,846...108,861,296
G
Pgap2
post-GPI attachment to proteins 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PGAP2 mRNA
CTD
PMID:18636392
NCBI chr 7:101,859,153...101,887,771
Ensembl chr 7:101,859,415...101,887,774
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Phb1
prohibitin 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of PHB1 mRNA [Ozone co-treated with Chlorine] results in increased expression of PHB1 mRNA
CTD
PMID:18636392
NCBI chr11:95,557,783...95,571,599
Ensembl chr11:95,557,783...95,571,599
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Pi4ka
phosphatidylinositol 4-kinase alpha
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of PI4KA mRNA [Ozone co-treated with Chlorine] affects the expression of PI4KA mRNA
CTD
PMID:18636392
NCBI chr16:17,098,215...17,224,178
Ensembl chr16:17,098,215...17,224,178
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Pla2g2c
phospholipase A2, group IIC
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PLA2G2C mRNA
CTD
PMID:18636392
NCBI chr 4:138,452,636...138,471,886
Ensembl chr 4:138,452,103...138,473,443
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Plac8
placenta-specific 8
increases expression
EXP
Chlorine results in increased expression of PLAC8 mRNA
CTD
PMID:30189237
NCBI chr 5:100,699,455...100,720,119
Ensembl chr 5:100,701,591...100,720,111
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Plat
plasminogen activator, tissue
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNA
CTD
PMID:18636392
NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
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Plec
plectin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA
CTD
PMID:18636392
NCBI chr15:76,055,174...76,115,578
Ensembl chr15:76,055,174...76,116,774
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Plpp1
phospholipid phosphatase 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLPP1 mRNA Chlorine results in decreased expression of PLPP1 mRNA
CTD
PMID:18636392
NCBI chr13:112,937,311...113,004,428
Ensembl chr13:112,937,326...113,004,428
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Pmp22
peripheral myelin protein 22
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PMP22 mRNA
CTD
PMID:18636392
NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373
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Pnlip
pancreatic lipase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PNLIP mRNA
CTD
PMID:18636392
NCBI chr19:58,658,797...58,670,231
Ensembl chr19:58,640,930...58,670,220
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Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PPP2CA mRNA
CTD
PMID:18636392
NCBI chr11:51,989,651...52,013,576
Ensembl chr11:51,989,508...52,018,605
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Ppp2cb
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PPP2CB mRNA
CTD
PMID:18636392
NCBI chr 8:34,089,672...34,109,831
Ensembl chr 8:34,089,653...34,109,469
G
Prdx2
peroxiredoxin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA
CTD
PMID:18636392
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Prmt1
protein arginine N-methyltransferase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PRMT1 mRNA
CTD
PMID:18636392
NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
G
Psma1
proteasome subunit alpha 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA1 mRNA
CTD
PMID:18636392
NCBI chr 7:113,863,785...113,875,351
Ensembl chr 7:113,863,841...113,875,353
G
Psma2
proteasome subunit alpha 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA2 mRNA
CTD
PMID:18636392
NCBI chr13:14,787,827...14,800,258
Ensembl chr13:14,787,825...14,848,821
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Psma3
proteasome subunit alpha 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMA3L mRNA [Ozone co-treated with Chlorine] affects the expression of PSMA3L mRNA
CTD
PMID:18636392
NCBI chr12:71,016,082...71,042,651
Ensembl chr12:71,021,395...71,043,121
G
Psma4
proteasome subunit alpha 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA4 mRNA
CTD
PMID:18636392
NCBI chr 9:54,858,074...54,865,316
Ensembl chr 9:54,858,074...54,865,314
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Psmb3
proteasome (prosome, macropain) subunit, beta type 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB3 mRNA
CTD
PMID:18636392
NCBI chr11:97,594,260...97,604,326
Ensembl chr11:97,594,225...97,604,326
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Psmb4
proteasome (prosome, macropain) subunit, beta type 4
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMB4 mRNA [Ozone co-treated with Chlorine] affects the expression of PSMB4 mRNA
CTD
PMID:18636392
NCBI chr 3:94,791,635...94,794,269
Ensembl chr 3:94,791,404...94,794,272
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Psmb6
proteasome (prosome, macropain) subunit, beta type 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB6 mRNA
CTD
PMID:18636392
NCBI chr11:70,416,116...70,418,684
Ensembl chr11:70,416,193...70,418,684
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Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA
CTD
PMID:18636392
NCBI chr17:34,417,169...34,420,428
Ensembl chr17:34,416,695...34,420,428
G
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNA
CTD
PMID:18636392
NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664
G
Psmc2
proteasome (prosome, macropain) 26S subunit, ATPase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMC2 mRNA
CTD
PMID:18636392
NCBI chr 5:21,990,273...22,008,785
Ensembl chr 5:21,990,281...22,008,785
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Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA
CTD
PMID:18636392
NCBI chr 7:27,741,127...27,749,517
Ensembl chr 7:27,741,132...27,749,526
G
Psmc5
protease (prosome, macropain) 26S subunit, ATPase 5
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMC5 mRNA [Ozone co-treated with Chlorine] affects the expression of PSMC5 mRNA
CTD
PMID:18636392
NCBI chr11:106,147,011...106,153,938
Ensembl chr11:106,146,980...106,153,946
G
Ptafr
platelet-activating factor receptor
increases expression multiple interactions
ISO
Chlorine results in increased expression of PTAFR mRNA [Ozone co-treated with Chlorine] affects the expression of PTAFR mRNA
CTD
PMID:18636392
NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
EXP
Chlorine results in increased expression of PTGS2 mRNA
CTD
PMID:24582687
NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
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Ptn
pleiotrophin
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of PTN mRNA Chlorine results in increased expression of PTN mRNA
CTD
PMID:18636392
NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
G
Ptpn11
protein tyrosine phosphatase, non-receptor type 11
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PTPN11 mRNA
CTD
PMID:18636392
NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460
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Ptpn7
protein tyrosine phosphatase, non-receptor type 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PTPN7 mRNA
CTD
PMID:18636392
NCBI chr 1:135,059,577...135,073,064
Ensembl chr 1:135,060,438...135,073,055
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Ptprr
protein tyrosine phosphatase receptor type R
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of PTPRR mRNA [Ozone co-treated with Chlorine] affects the expression of PTPRR mRNA
CTD
PMID:18636392
NCBI chr10:115,854,093...116,110,837
Ensembl chr10:115,854,118...116,110,837
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Rab15
RAB15, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB15 mRNA [Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA
CTD
PMID:18636392
NCBI chr12:76,844,734...76,869,532
Ensembl chr12:76,844,734...76,869,682
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Rab1a
RAB1A, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB1A mRNA [Ozone co-treated with Chlorine] affects the expression of RAB1A mRNA
CTD
PMID:18636392
NCBI chr11:20,151,412...20,176,856
Ensembl chr11:20,151,432...20,176,856
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Rab2a
RAB2A, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of RAB2 mRNA
CTD
PMID:18636392
NCBI chr 4:8,535,661...8,607,708
Ensembl chr 4:8,535,644...8,607,778
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Rab3b
RAB3B, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA
CTD
PMID:18636392
NCBI chr 4:108,736,267...108,800,521
Ensembl chr 4:108,736,260...108,800,521
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Rab3d
RAB3D, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA
CTD
PMID:18636392
NCBI chr 9:21,818,787...21,829,623
Ensembl chr 9:21,818,787...21,829,488
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Rab4a
RAB4A, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RAB4A mRNA
CTD
PMID:18636392
NCBI chr 8:124,532,748...124,562,030
Ensembl chr 8:124,532,724...124,562,026
G
Rala
v-ral simian leukemia viral oncogene A (ras related)
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of RALA mRNA
CTD
PMID:18636392
NCBI chr13:18,055,160...18,118,802
Ensembl chr13:18,055,156...18,118,824
G
Ralgds
ral guanine nucleotide dissociation stimulator
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of RALGDS mRNA Chlorine results in increased expression of RALGDS mRNA
CTD
PMID:18636392
NCBI chr 2:28,403,037...28,443,085
Ensembl chr 2:28,403,137...28,443,093
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Rasa1
RAS p21 protein activator 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RASA1 mRNA
CTD
PMID:18636392
NCBI chr13:85,362,893...85,437,487
Ensembl chr13:85,362,899...85,437,249
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Retnla
resistin like alpha
increases expression
EXP
Chlorine results in increased expression of RETNLA mRNA; Chlorine results in increased expression of RETNLA protein
CTD
PMID:24582687
NCBI chr16:48,662,972...48,664,824
Ensembl chr16:48,662,914...48,664,824
G
Rims1
regulating synaptic membrane exocytosis 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA
CTD
PMID:18636392
NCBI chr 1:22,356,196...22,845,239
Ensembl chr 1:22,356,475...22,845,203
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Rin1
Ras and Rab interactor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RIN1 mRNA
CTD
PMID:18636392
NCBI chr19:5,100,035...5,107,100
Ensembl chr19:5,100,509...5,107,099
G
Rnpep
arginyl aminopeptidase (aminopeptidase B)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RNPEP mRNA
CTD
PMID:18636392
NCBI chr 1:135,190,447...135,211,765
Ensembl chr 1:135,190,450...135,211,822
G
Rpl10
ribosomal protein L10
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNA
CTD
PMID:18636392
NCBI chr X:73,314,463...73,316,741
Ensembl chr X:73,314,418...73,316,741
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Rpl11
ribosomal protein L11
increases expression multiple interactions
ISO
Chlorine results in increased expression of RPL11 mRNA [Ozone co-treated with Chlorine] affects the expression of RPL11 mRNA
CTD
PMID:18636392
NCBI chr 4:135,776,665...135,780,704
Ensembl chr 4:135,755,576...135,780,739
G
Rpl12
ribosomal protein L12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL12 mRNA
CTD
PMID:18636392
NCBI chr 2:32,851,724...32,854,057
Ensembl chr 2:32,851,571...32,855,357
G
Rpl13
ribosomal protein L13
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL13 mRNA
CTD
PMID:18636392
NCBI chr 8:123,829,089...123,831,983
Ensembl chr 8:123,829,089...123,831,983
G
Rpl21
ribosomal protein L21
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL21 mRNA
CTD
PMID:18636392
NCBI chr 5:146,769,955...146,773,842
Ensembl chr 5:146,769,700...146,773,842
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Rpl36al
ribosomal protein L36A-like
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL36AL mRNA
CTD
PMID:18636392
NCBI chr12:69,229,508...69,230,841
Ensembl chr12:69,229,505...69,230,857
G
Rps11
ribosomal protein S11
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA
CTD
PMID:18636392
NCBI chr 7:44,771,812...44,773,813
Ensembl chr 7:44,771,803...44,773,863
G
Rps12
ribosomal protein S12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS12 mRNA
CTD
PMID:18636392
NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173
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Rps17
ribosomal protein S17
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS17 mRNA
CTD
PMID:18636392
NCBI chr 7:80,992,481...80,994,982
Ensembl chr 7:80,992,480...80,995,002
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Rps19
ribosomal protein S19
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of RPS19 mRNA Chlorine results in increased expression of RPS19 mRNA
CTD
PMID:18636392
NCBI chr 7:24,584,013...24,589,236
Ensembl chr 7:24,583,796...24,589,231
G
Rps29
ribosomal protein S29
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS29 mRNA
CTD
PMID:18636392
NCBI chr12:69,204,495...69,205,891
Ensembl chr12:69,204,496...69,205,960
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Rps4x
ribosomal protein S4, X-linked
increases expression multiple interactions
ISO
Chlorine results in increased expression of RPS4X mRNA [Ozone co-treated with Chlorine] results in decreased expression of RPS4X mRNA
CTD
PMID:18636392
NCBI chr X:101,228,548...101,232,929
Ensembl chr X:101,228,547...101,233,000
G
S1pr2
sphingosine-1-phosphate receptor 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of S1PR2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of S1PR2 mRNA
CTD
PMID:18636392
NCBI chr 9:20,877,248...20,888,089
Ensembl chr 9:20,873,657...20,888,077
G
Scn2b
sodium channel, voltage-gated, type II, beta
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SCN2B mRNA [Ozone co-treated with Chlorine] affects the expression of SCN2B mRNA
CTD
PMID:18636392
NCBI chr 9:45,029,174...45,041,368
Ensembl chr 9:45,029,080...45,041,368
G
Scn4a
sodium channel, voltage-gated, type IV, alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SCN4A mRNA
CTD
PMID:18636392
NCBI chr11:106,208,374...106,256,385
Ensembl chr11:106,209,418...106,244,114
G
Scp2
sterol carrier protein 2, liver
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SCP2 mRNA [Ozone co-treated with Chlorine] affects the expression of SCP2 mRNA
CTD
PMID:18636392
NCBI chr 4:107,901,027...108,002,168
Ensembl chr 4:107,901,036...108,002,195
G
Sctr
secretin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA
CTD
PMID:18636392
NCBI chr 1:119,934,710...119,991,269
Ensembl chr 1:119,934,624...119,991,266
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Selp
selectin, platelet
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SELP mRNA
CTD
PMID:18636392
NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
G
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
increases expression
EXP
Chlorine results in increased expression of SERPINB2 mRNA
CTD
PMID:30189237
NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208
G
Serpinb5
serine (or cysteine) peptidase inhibitor, clade B, member 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SERPINB5 mRNA
CTD
PMID:18636392
NCBI chr 1:106,788,905...106,811,078
Ensembl chr 1:106,788,903...106,811,078
G
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of SERPINE1 mRNA [Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNA
CTD
PMID:18636392
NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
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Sftpb
surfactant associated protein B
affects expression
EXP
Chlorine affects the expression of SFTPB protein
CTD
PMID:24582687
NCBI chr 6:72,281,594...72,291,354
Ensembl chr 6:72,281,594...72,291,354
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Sftpd
surfactant associated protein D
affects expression increases expression
EXP
Chlorine affects the expression of SFTPD protein Chlorine results in increased expression of SFTPD protein
CTD
PMID:24582687 PMID:36690086
NCBI chr14:40,894,169...40,907,155
Ensembl chr14:40,894,171...40,907,106
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Sgk1
serum/glucocorticoid regulated kinase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SGK1 mRNA [Ozone co-treated with Chlorine] results in increased expression of SGK1 mRNA
CTD
PMID:18636392
NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
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Siglec1
sialic acid binding Ig-like lectin 1, sialoadhesin
increases expression
EXP
Chlorine results in increased expression of SIGLEC1 mRNA
CTD
PMID:30189237
NCBI chr 2:130,911,140...130,928,697
Ensembl chr 2:130,911,140...130,928,685
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Sirpa
signal-regulatory protein alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SIRPA mRNA
CTD
PMID:18636392
NCBI chr 2:129,432,962...129,474,148
Ensembl chr 2:129,434,755...129,474,148
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Slc10a1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SLC10A1 mRNA [Ozone co-treated with Chlorine] affects the expression of SLC10A1 mRNA
CTD
PMID:18636392
NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
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Slc14a2
solute carrier family 14 (urea transporter), member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC14A2 mRNA
CTD
PMID:18636392
NCBI chr18:78,189,359...78,640,165
Ensembl chr18:78,189,363...78,640,157
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Slc15a1
solute carrier family 15 (oligopeptide transporter), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC15A1 mRNA
CTD
PMID:18636392
NCBI chr14:121,697,033...121,742,666
Ensembl chr14:121,697,033...121,742,664
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Slc15a4
solute carrier family 15, member 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC15A4 mRNA
CTD
PMID:18636392
NCBI chr 5:127,668,795...127,710,356
Ensembl chr 5:127,672,728...127,709,961
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Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNA
CTD
PMID:18636392
NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
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Slc17a1
solute carrier family 17 (sodium phosphate), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA
CTD
PMID:18636392
NCBI chr13:24,051,607...24,079,713
Ensembl chr13:24,051,733...24,079,713
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Slc18a1
solute carrier family 18 (vesicular monoamine), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC18A1 mRNA
CTD
PMID:18636392
NCBI chr 8:69,490,360...69,547,951
Ensembl chr 8:69,490,363...69,541,887
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Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA
CTD
PMID:18636392
NCBI chr10:78,615,923...78,650,659
Ensembl chr10:78,616,330...78,650,599
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Slc22a1
solute carrier family 22 (organic cation transporter), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC22A1 mRNA
CTD
PMID:18636392
NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
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Slc22a12
solute carrier family 22 (organic anion/cation transporter), member 12
multiple interactions
ISO
[Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluoro-n-nonanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorodecanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorooctanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of perfluorooctanoic acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]
CTD
PMID:20639259
NCBI chr19:6,585,884...6,593,100
Ensembl chr19:6,585,875...6,593,062
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Slc22a2
solute carrier family 22 (organic cation transporter), member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA
CTD
PMID:18636392
NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
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Slc4a2
solute carrier family 4 (anion exchanger), member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC4A2 mRNA
CTD
PMID:18636392
NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
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Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNA
CTD
PMID:18636392
NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
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Slc6a15
solute carrier family 6 (neurotransmitter transporter), member 15
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA
CTD
PMID:18636392
NCBI chr10:103,203,320...103,255,240
Ensembl chr10:103,203,644...103,255,238
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Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC6A9 mRNA
CTD
PMID:18636392
NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
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Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC7A1 mRNA
CTD
PMID:18636392
NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714
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Slc9a2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC9A2 mRNA
CTD
PMID:18636392
NCBI chr 1:40,720,872...40,808,045
Ensembl chr 1:40,719,734...40,808,433
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Slco1a4
solute carrier organic anion transporter family, member 1a4
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLCO1A4 mRNA Chlorine results in decreased expression of SLCO1A4 mRNA
CTD
PMID:18636392
NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
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Slpi
secretory leukocyte peptidase inhibitor
increases expression
EXP
Chlorine results in increased expression of SLPI mRNA
CTD
PMID:30189237
NCBI chr 2:164,195,990...164,231,086
Ensembl chr 2:164,195,990...164,231,015
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Smad1
SMAD family member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SMAD1 mRNA
CTD
PMID:18636392
NCBI chr 8:80,065,024...80,126,057
Ensembl chr 8:80,065,024...80,126,147
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Smn1
survival motor neuron 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SMN1 mRNA
CTD
PMID:18636392
NCBI chr13:100,259,713...100,274,206
Ensembl chr13:100,261,360...100,274,198
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Snap25
synaptosomal-associated protein 25
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SNAP25 mRNA
CTD
PMID:18636392
NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348
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Spon1
spondin 1, (f-spondin) extracellular matrix protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA
CTD
PMID:18636392
NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605
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Ssrp1
structure specific recognition protein 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SSRP1 mRNA
CTD
PMID:18636392
NCBI chr 2:84,867,519...84,877,453
Ensembl chr 2:84,867,578...84,877,453
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Sst
somatostatin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SST mRNA
CTD
PMID:18636392
NCBI chr16:23,708,327...23,710,041
Ensembl chr16:23,708,323...23,709,708
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Sstr3
somatostatin receptor 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SSTR3 mRNA
CTD
PMID:18636392
NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885
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Stx1b
syntaxin 1B
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX1B mRNA
CTD
PMID:18636392
NCBI chr 7:127,403,072...127,423,703
Ensembl chr 7:127,403,072...127,423,721
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Stx5a
syntaxin 5A
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX5A mRNA
CTD
PMID:18636392
NCBI chr19:8,718,788...8,733,006
Ensembl chr19:8,718,777...8,733,433
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Stx6
syntaxin 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX6 mRNA
CTD
PMID:18636392
NCBI chr 1:155,034,374...155,083,405
Ensembl chr 1:155,034,461...155,084,002
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Sult1b1
sulfotransferase family 1B, member 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of SULT1B1 mRNA Chlorine results in decreased expression of SULT1B1 mRNA
CTD
PMID:18636392
NCBI chr 5:87,661,186...87,686,054
Ensembl chr 5:87,661,198...87,686,054
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Sv2b
synaptic vesicle glycoprotein 2b
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of SV2B mRNA Chlorine results in increased expression of SV2B mRNA
CTD
PMID:18636392
NCBI chr 7:74,764,642...74,959,143
Ensembl chr 7:74,764,642...74,959,010
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Syp
synaptophysin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA
CTD
PMID:18636392
NCBI chr X:7,504,819...7,519,495
Ensembl chr X:7,504,710...7,519,495
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Syt11
synaptotagmin XI
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SYT11 mRNA [Ozone co-treated with Chlorine] results in decreased expression of SYT11 mRNA
CTD
PMID:18636392
NCBI chr 3:88,652,006...88,682,466
Ensembl chr 3:88,652,007...88,682,471
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Syt2
synaptotagmin II
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYT2 mRNA
CTD
PMID:18636392
NCBI chr 1:134,574,319...134,680,887
Ensembl chr 1:134,574,415...134,690,331
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Syt4
synaptotagmin IV
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYT4 mRNA
CTD
PMID:18636392
NCBI chr18:31,570,861...31,580,468
Ensembl chr18:31,570,861...31,580,459
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Tacr2
tachykinin receptor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of TACR2 mRNA
CTD
PMID:18636392
NCBI chr10:62,088,217...62,101,769
Ensembl chr10:62,088,217...62,101,769
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Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TAP2 mRNA
CTD
PMID:18636392
NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295
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Tbxa2r
thromboxane A2 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of TBXA2R mRNA
CTD
PMID:18636392
NCBI chr10:81,164,102...81,171,008
Ensembl chr10:81,164,565...81,171,006
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Tfrc
transferrin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TFRC mRNA
CTD
PMID:18636392
NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612
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Tgfbr1
transforming growth factor, beta receptor I
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of TGFBR1 mRNA
CTD
PMID:18636392
NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
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Timp1
tissue inhibitor of metalloproteinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA
CTD
PMID:18636392
NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974
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Tk1
thymidine kinase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of TK1 mRNA [Ozone co-treated with Chlorine] affects the expression of TK1 mRNA
CTD
PMID:18636392
NCBI chr11:117,706,345...117,716,913
Ensembl chr11:117,706,352...117,716,918
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Tnf
tumor necrosis factor
increases expression
EXP
Chlorine results in increased expression of TNF protein
CTD
PMID:23146759
NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
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Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
increases expression
ISO
Chlorine results in increased expression of TNFRSF1A protein
CTD
PMID:35065218
NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
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Top2a
topoisomerase (DNA) II alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TOP2A mRNA
CTD
PMID:18636392
NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
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Tpp2
tripeptidyl peptidase II
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TPP2 mRNA
CTD
PMID:18636392
NCBI chr 1:43,973,130...44,042,160
Ensembl chr 1:43,972,807...44,042,160
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Trp53
transformation related protein 53
increases expression multiple interactions
ISO
Chlorine results in increased expression of TP53 protein modified form Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form]
CTD
PMID:35065218
NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
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Tuba1a
tubulin, alpha 1A
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TUBA1A mRNA
CTD
PMID:18636392
NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584
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Tyms
thymidylate synthase
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of TYMS mRNA [Ozone co-treated with Chlorine] affects the expression of TYMS mRNA
CTD
PMID:18636392
NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
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Unc5b
unc-5 netrin receptor B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of UNC5B mRNA
CTD
PMID:18636392
NCBI chr10:60,598,373...60,667,360
Ensembl chr10:60,598,372...60,667,360
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Vcp
valosin containing protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of VCP mRNA
CTD
PMID:18636392
NCBI chr 4:42,979,964...43,000,507
Ensembl chr 4:42,979,963...43,000,507
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Vhl
von Hippel-Lindau tumor suppressor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VHL mRNA
CTD
PMID:18636392
NCBI chr 6:113,600,955...113,608,595
Ensembl chr 6:113,600,920...113,608,594
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Vipr1
vasoactive intestinal peptide receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VIPR1 mRNA
CTD
PMID:18636392
NCBI chr 9:121,471,782...121,502,020
Ensembl chr 9:121,471,782...121,502,020
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Vipr2
vasoactive intestinal peptide receptor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VIPR2 mRNA
CTD
PMID:18636392
NCBI chr12:116,041,040...116,117,842
Ensembl chr12:116,041,346...116,109,881
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Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of YWHAE mRNA
CTD
PMID:18636392
NCBI chr11:75,620,121...75,656,667
Ensembl chr11:75,623,695...75,656,671
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of YWHAG mRNA Chlorine results in increased expression of YWHAG mRNA
CTD
PMID:18636392
NCBI chr 5:135,937,233...135,963,495
Ensembl chr 5:135,937,263...135,963,470
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Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of YWHAH mRNA
CTD
PMID:18636392
NCBI chr 5:33,176,160...33,185,310
Ensembl chr 5:33,176,160...33,185,310
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
increases expression multiple interactions
ISO
Chlorine results in increased expression of YWHAZ mRNA [Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA
CTD
PMID:18636392
NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
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