CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: diatomic chlorine
Accession: CHEBI:33435
browse the term
Synonyms: related_synonym: Formula=Cl2
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ABCC1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ABCC1 mRNA
CTD
PMID:18636392
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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ACADM
acyl-CoA dehydrogenase medium chain
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ACADM mRNA
CTD
PMID:18636392
NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
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ACHE
acetylcholinesterase (Yt blood group)
multiple interactions
EXP
[[Chlorine co-treated with Diazinon] results in increased abundance of diazoxon] which results in decreased activity of ACHE protein
CTD
PMID:34374289
NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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ACOT7
acyl-CoA thioesterase 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ACOT7 mRNA
CTD
PMID:18636392
NCBI chr 1:6,264,272...6,393,767
Ensembl chr 1:6,264,269...6,393,767
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ACSL1
acyl-CoA synthetase long chain family member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ACSL1 mRNA [Ozone co-treated with Chlorine] affects the expression of ACSL1 mRNA
CTD
PMID:18636392
NCBI chr 4:184,755,595...184,826,594
Ensembl chr 4:184,755,595...184,826,818
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ACVR1
activin A receptor type 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ACVR1 mRNA
CTD
PMID:18636392
NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330
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ADCY2
adenylate cyclase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY2 mRNA
CTD
PMID:18636392
NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081
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ADCY3
adenylate cyclase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADCY3 mRNA
CTD
PMID:18636392
NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237
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ADCY4
adenylate cyclase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADCY4 mRNA
CTD
PMID:18636392
NCBI chr14:24,318,359...24,335,071
Ensembl chr14:24,318,349...24,335,093
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ADCY5
adenylate cyclase 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY5 mRNA
CTD
PMID:18636392
NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090
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ADCY8
adenylate cyclase 8
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADCY8 mRNA
CTD
PMID:18636392
NCBI chr 8:130,780,301...131,040,909
Ensembl chr 8:130,780,301...131,040,909
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ADGRL1
adhesion G protein-coupled receptor L1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ADGRL1 mRNA [Ozone co-treated with Chlorine] results in increased expression of ADGRL1 mRNA
CTD
PMID:18636392
NCBI chr19:14,147,743...14,206,169
Ensembl chr19:14,147,743...14,206,187
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ADORA3
adenosine A3 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADORA3 mRNA
CTD
PMID:18636392
NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
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ADRA2C
adrenoceptor alpha 2C
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ADRA2C mRNA
CTD
PMID:18636392
NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526
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ADRB2
adrenoceptor beta 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ADRB2 mRNA
CTD
PMID:18636392
NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623
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AGER
advanced glycosylation end-product specific receptor
decreases expression increases expression multiple interactions
ISO
Chlorine results in decreased expression of AGER mRNA Chlorine results in increased expression of AGER protein [Ozone co-treated with Chlorine] results in increased expression of AGER mRNA
CTD
PMID:18636392 PMID:36690086
NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
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AKR1A1
aldo-keto reductase family 1 member A1
increases expression multiple interactions
ISO
Chlorine results in increased expression of AKR1A1 mRNA [Ozone co-treated with Chlorine] results in decreased expression of AKR1A1 mRNA
CTD
PMID:18636392
NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
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AKT1
AKT serine/threonine kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of AKT1 mRNA
CTD
PMID:18636392
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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AKT2
AKT serine/threonine kinase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of AKT2 mRNA
CTD
PMID:18636392
NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536
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ALDOC
aldolase, fructose-bisphosphate C
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ALDOC mRNA
CTD
PMID:18636392
NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
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AMACR
alpha-methylacyl-CoA racemase
increases expression multiple interactions
ISO
Chlorine results in increased expression of AMACR mRNA [Ozone co-treated with Chlorine] results in increased expression of AMACR mRNA
CTD
PMID:18636392
NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104
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AMPH
amphiphysin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of AMPH mRNA
CTD
PMID:18636392
NCBI chr 7:38,383,704...38,631,373
Ensembl chr 7:38,383,704...38,631,420
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ANXA2
annexin A2
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA2 mRNA Chlorine results in increased expression of ANXA2 mRNA
CTD
PMID:18636392
NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
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ANXA3
annexin A3
increases expression multiple interactions
ISO
Chlorine results in increased expression of ANXA3 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ANXA3 mRNA
CTD
PMID:18636392
NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
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ANXA4
annexin A4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA4 mRNA
CTD
PMID:18636392
NCBI chr 2:69,643,808...69,827,112
Ensembl chr 2:69,644,425...69,827,112
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ANXA5
annexin A5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ANXA5 mRNA
CTD
PMID:18636392
NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995
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APC
APC regulator of WNT signaling pathway
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of APC mRNA
CTD
PMID:18636392
NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239
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APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of APEX1 mRNA
CTD
PMID:18636392
NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
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APOA1
apolipoprotein A1
multiple interactions affects binding
EXP
[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein
CTD
PMID:33861588
NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
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APOD
apolipoprotein D
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of APOD mRNA
CTD
PMID:18636392
NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
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AQP1
aquaporin 1 (Colton blood group)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of AQP1 mRNA
CTD
PMID:18636392
NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517
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AQP3
aquaporin 3 (Gill blood group)
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of AQP3 mRNA [Ozone co-treated with Chlorine] affects the expression of AQP3 mRNA
CTD
PMID:18636392
NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
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ARF1
ARF GTPase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF1 mRNA
CTD
PMID:18636392
NCBI chr 1:228,082,708...228,099,212
Ensembl chr 1:228,082,708...228,099,212
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ARF3
ARF GTPase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF3 mRNA
CTD
PMID:18636392
NCBI chr12:48,935,723...48,957,487
Ensembl chr12:48,935,723...48,957,487
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ARF4
ARF GTPase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ARF4 mRNA
CTD
PMID:18636392
NCBI chr 3:57,571,363...57,597,344
Ensembl chr 3:57,571,363...57,598,220
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ARF5
ARF GTPase 5
increases expression multiple interactions
ISO
Chlorine results in increased expression of ARF5 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ARF5 mRNA
CTD
PMID:18636392
NCBI chr 7:127,588,411...127,591,700
Ensembl chr 7:127,588,386...127,591,700
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ARF6
ARF GTPase 6
increases expression multiple interactions
ISO
Chlorine results in increased expression of ARF6 mRNA [Ozone co-treated with Chlorine] affects the expression of ARF6 mRNA
CTD
PMID:18636392
NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,079...49,897,054
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ARG1
arginase 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of ARG1 mRNA Chlorine results in increased expression of ARG1 mRNA; Chlorine results in increased expression of ARG1 protein
CTD
PMID:18636392 PMID:24582687 PMID:30189237
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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ARHGAP35
Rho GTPase activating protein 35
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ARHGAP35 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ARHGAP35 mRNA
CTD
PMID:18636392
NCBI chr19:46,860,997...47,005,077
Ensembl chr19:46,860,997...47,005,077
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ARRB2
arrestin beta 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of ARRB2 mRNA
CTD
PMID:18636392
NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
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ATF2
activating transcription factor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATF2 mRNA
CTD
PMID:18636392
NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382
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ATP1A1
ATPase Na+/K+ transporting subunit alpha 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATP1A1 mRNA Chlorine results in decreased expression of ATP1A1 mRNA
CTD
PMID:18636392 PMID:24218892
NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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ATP2A3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of ATP2A3 mRNA [Ozone co-treated with Chlorine] results in decreased expression of ATP2A3 mRNA
CTD
PMID:18636392
NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,868...3,964,464
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ATP6V0C
ATPase H+ transporting V0 subunit c
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ATP6V0C mRNA
CTD
PMID:18636392
NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
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ATP7B
ATPase copper transporting beta
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ATP7B mRNA
CTD
PMID:18636392
NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
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BAX
BCL2 associated X, apoptosis regulator
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of BAX mRNA
CTD
PMID:18636392
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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BDKRB2
bradykinin receptor B2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of BDKRB2 mRNA
CTD
PMID:18636392
NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
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BMP4
bone morphogenetic protein 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of BMP4 mRNA
CTD
PMID:18636392
NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
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C5AR1
complement C5a receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of C5AR1 mRNA
CTD
PMID:18636392
NCBI chr19:47,307,477...47,322,066
Ensembl chr19:47,290,023...47,322,066
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CA3
carbonic anhydrase 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CA3 mRNA [Ozone co-treated with Chlorine] affects the expression of CA3 mRNA
CTD
PMID:18636392
NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040
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CACNA1A
calcium voltage-gated channel subunit alpha1 A
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CACNA1A mRNA
CTD
PMID:18636392
NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,624,489
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CACNA1B
calcium voltage-gated channel subunit alpha1 B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CACNA1B mRNA
CTD
PMID:18636392
NCBI chr 9:137,877,782...138,124,619
Ensembl chr 9:137,877,782...138,124,624
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CACNB3
calcium voltage-gated channel auxiliary subunit beta 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CACNB3 mRNA
CTD
PMID:18636392
NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941
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CARTPT
CART prepropeptide
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CARTPT mRNA [Ozone co-treated with Chlorine] affects the expression of CARTPT mRNA
CTD
PMID:18636392
NCBI chr 5:71,719,275...71,721,045
Ensembl chr 5:71,719,275...71,721,048
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CASP3
caspase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CASP3 mRNA
CTD
PMID:18636392
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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CASR
calcium sensing receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CASR mRNA
CTD
PMID:18636392
NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629
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CAST
calpastatin
increases expression multiple interactions
ISO
Chlorine results in increased expression of CAST mRNA [Ozone co-treated with Chlorine] affects the expression of CAST mRNA
CTD
PMID:18636392
NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595 Ensembl chr 5:96,247,756...96,779,595
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CAT
catalase
increases expression multiple interactions
EXP ISO
Chlorine results in increased expression of CAT protein Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]
CTD
PMID:35065218 PMID:36690086
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CCKBR
cholecystokinin B receptor
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CCKBR mRNA [Ozone co-treated with Chlorine] results in increased expression of CCKBR mRNA
CTD
PMID:18636392
NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
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CCL11
C-C motif chemokine ligand 11
increases expression
ISO
Chlorine results in increased expression of CCL11 protein
CTD
PMID:23146759
NCBI chr17:34,285,742...34,288,334
Ensembl chr17:34,285,742...34,288,334
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CCL13
C-C motif chemokine ligand 13
increases expression
ISO
Chlorine results in increased expression of CCL12 mRNA
CTD
PMID:30189237
NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
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CCL15
C-C motif chemokine ligand 15
increases expression
ISO
Chlorine results in increased expression of CCL6 mRNA
CTD
PMID:30189237
NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553
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CCL2
C-C motif chemokine ligand 2
increases expression decreases secretion multiple interactions
ISO EXP
Chlorine results in increased expression of CCL2 mRNA; Chlorine results in increased expression of CCL2 protein Chlorine results in decreased secretion of CCL2 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]
CTD
PMID:23146759 PMID:24582687 PMID:30189237 PMID:35065218
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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CCL20
C-C motif chemokine ligand 20
increases expression
ISO
Chlorine results in increased expression of CCL20 mRNA
CTD
PMID:24582687
NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
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CCL3
C-C motif chemokine ligand 3
increases expression
ISO
Chlorine results in increased expression of CCL3 protein
CTD
PMID:23146759
NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169
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CCL5
C-C motif chemokine ligand 5
increases expression multiple interactions
ISO
Chlorine results in increased expression of CCL5 protein [Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA
CTD
PMID:23146759 PMID:31066272
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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CCL7
C-C motif chemokine ligand 7
increases expression
ISO
Chlorine results in increased expression of CCL7 mRNA
CTD
PMID:30189237
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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CCL8
C-C motif chemokine ligand 8
increases expression
ISO
Chlorine results in increased expression of CCL8 mRNA
CTD
PMID:30189237
NCBI chr17:34,319,435...34,321,402
Ensembl chr17:34,319,435...34,321,402
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CCNC
cyclin C
increases expression multiple interactions
ISO
Chlorine results in increased expression of CCNC mRNA [Ozone co-treated with Chlorine] results in decreased expression of CCNC mRNA
CTD
PMID:18636392
NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825
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CCND1
cyclin D1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCND1 mRNA
CTD
PMID:18636392
NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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CCND3
cyclin D3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCND3 mRNA
CTD
PMID:18636392
NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
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CCNG1
cyclin G1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CCNG1 mRNA
CTD
PMID:18636392
NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,448,199
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CD4
CD4 molecule
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CD4 mRNA [Ozone co-treated with Chlorine] affects the expression of CD4 mRNA
CTD
PMID:18636392
NCBI chr12:6,789,528...6,820,799
Ensembl chr12:6,786,858...6,820,799
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CD44
CD44 molecule (IN blood group)
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CD44 mRNA
CTD
PMID:18636392
NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402
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CD9
CD9 molecule
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CD9 mRNA
CTD
PMID:18636392
NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271
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CDC25B
cell division cycle 25B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CDC25B mRNA
CTD
PMID:18636392
NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
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CDH22
cadherin 22
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA
CTD
PMID:18636392
NCBI chr20:46,173,739...46,308,498
Ensembl chr20:46,173,739...46,308,498
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CDK4
cyclin dependent kinase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA
CTD
PMID:18636392
NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
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CDKN1A
cyclin dependent kinase inhibitor 1A
increases expression multiple interactions
ISO
Chlorine results in increased expression of CDKN1A mRNA [Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA
CTD
PMID:18636392
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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CDKN2B
cyclin dependent kinase inhibitor 2B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CDKN2B mRNA
CTD
PMID:18636392
NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
G
CFL1
cofilin 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CFL1 mRNA
CTD
PMID:18636392
NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
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CFTR
CF transmembrane conductance regulator
multiple interactions increases transport
ISO EXP
CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]; Nitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]] CFTR protein results in increased transport of Chlorine
CTD
PMID:12612912 PMID:21765217
NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
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CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
increases expression multiple interactions
ISO
Chlorine results in increased expression of CHRNA1 mRNA [Ozone co-treated with Chlorine] results in increased expression of CHRNA1 mRNA
CTD
PMID:18636392
NCBI chr 2:174,747,592...174,764,472
Ensembl chr 2:174,747,592...174,787,935
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CHRNA4
cholinergic receptor nicotinic alpha 4 subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CHRNA4 mRNA
CTD
PMID:18636392
NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401
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CHRNB1
cholinergic receptor nicotinic beta 1 subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CHRNB1 mRNA
CTD
PMID:18636392
NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710
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CKMT1B
creatine kinase, mitochondrial 1B
affects expression multiple interactions
ISO
Chlorine affects the expression of CKMT1 mRNA [Ozone co-treated with Chlorine] results in increased expression of CKMT1 mRNA
CTD
PMID:18636392
NCBI chr15:43,592,857...43,599,406
Ensembl chr15:43,593,054...43,604,901 Ensembl chr15:43,593,054...43,604,901
G
CLEC4D
C-type lectin domain family 4 member D
increases expression
ISO
Chlorine results in increased expression of CLEC4D mRNA
CTD
PMID:30189237
NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366
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CLU
clusterin
multiple interactions increases expression
ISO EXP
[Ozone co-treated with Chlorine] results in decreased expression of CLU mRNA Chlorine results in increased expression of CLU protein Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein]
CTD
PMID:18636392 PMID:35065218
NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
G
CMKLR1
chemerin chemokine-like receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CMKLR1 mRNA
CTD
PMID:18636392
NCBI chr12:108,288,046...108,339,311
Ensembl chr12:108,288,044...108,339,317
G
CNN3
calponin 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CNN3 mRNA
CTD
PMID:18636392
NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223
G
CNR1
cannabinoid receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CNR1 mRNA
CTD
PMID:18636392
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
G
CPD
carboxypeptidase D
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CPD mRNA
CTD
PMID:18636392
NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989
G
CPT1B
carnitine palmitoyltransferase 1B
increases expression multiple interactions
ISO
Chlorine results in increased expression of CPT1B mRNA [Ozone co-treated with Chlorine] results in decreased expression of CPT1B mRNA
CTD
PMID:18636392
NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465
G
CRHR2
corticotropin releasing hormone receptor 2
increases expression multiple interactions
ISO
Chlorine results in increased expression of CRHR2 mRNA [Ozone co-treated with Chlorine] affects the expression of CRHR2 mRNA
CTD
PMID:18636392
NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129
G
CRK
CRK proto-oncogene, adaptor protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CRK mRNA
CTD
PMID:18636392
NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
G
CSF1R
colony stimulating factor 1 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of CSF1R mRNA
CTD
PMID:18636392
NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
G
CSF2
colony stimulating factor 2
increases expression
ISO
Chlorine results in increased expression of CSF2 protein
CTD
PMID:23146759
NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
G
CSF3
colony stimulating factor 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of CSF3 mRNA Chlorine results in increased expression of CSF3 protein [Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA
CTD
PMID:18636392 PMID:23146759
NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
G
CSNK1G1
casein kinase 1 gamma 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of CSNK1G1 mRNA Chlorine results in decreased expression of CSNK1G1 mRNA
CTD
PMID:18636392
NCBI chr15:64,165,525...64,356,173
Ensembl chr15:64,165,525...64,356,173
G
CSRP3
cysteine and glycine rich protein 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of CSRP3 mRNA [Ozone co-treated with Chlorine] results in increased expression of CSRP3 mRNA
CTD
PMID:18636392
NCBI chr11:19,182,030...19,201,983
Ensembl chr11:19,182,030...19,210,571
G
CTSB
cathepsin B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CTSB mRNA
CTD
PMID:18636392
NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
G
CTSL
cathepsin L
increases expression multiple interactions
ISO
Chlorine results in increased expression of CTSL mRNA [Ozone co-treated with Chlorine] results in decreased expression of CTSL mRNA
CTD
PMID:18636392
NCBI chr 9:87,726,119...87,731,469
Ensembl chr 9:87,724,051...87,731,469
G
CXCL1
C-X-C motif chemokine ligand 1
multiple interactions increases expression
ISO
triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein] Chlorine results in increased expression of CXCL1 mRNA; Chlorine results in increased expression of CXCL1 protein
CTD
PMID:20348278 PMID:20819911 PMID:23146759 PMID:24582687
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
G
CXCL10
C-X-C motif chemokine ligand 10
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CXCL10 mRNA [Ozone co-treated with Chlorine] results in increased expression of CXCL10 mRNA
CTD
PMID:18636392
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
G
CXCL8
C-X-C motif chemokine ligand 8
decreases secretion multiple interactions
EXP
Chlorine results in decreased secretion of CXCL8 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CXCL8 protein]
CTD
PMID:35065218
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
G
CXCR4
C-X-C motif chemokine receptor 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of CXCR4 mRNA
CTD
PMID:18636392
NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
G
CYP11A1
cytochrome P450 family 11 subfamily A member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of CYP11A1 mRNA
CTD
PMID:18636392
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
G
CYP19A1
cytochrome P450 family 19 subfamily A member 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA Chlorine results in increased expression of CYP19A1 mRNA
CTD
PMID:18636392
NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
G
CYP2C18
cytochrome P450 family 2 subfamily C member 18
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of CYP2C mRNA [Ozone co-treated with Chlorine] affects the expression of CYP2C mRNA
CTD
PMID:18636392
NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190
G
DDC
dopa decarboxylase
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of DDC mRNA Chlorine results in decreased expression of DDC mRNA
CTD
PMID:18636392
NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
G
DDIT3
DNA damage inducible transcript 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of DDIT3 mRNA
CTD
PMID:18636392
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
G
DPP4
dipeptidyl peptidase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of DPP4 mRNA
CTD
PMID:18636392
NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
G
DPP6
dipeptidyl peptidase like 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of DPP6 mRNA
CTD
PMID:18636392
NCBI chr 7:153,748,133...154,894,285
Ensembl chr 7:153,748,133...154,894,285
G
DRD1
dopamine receptor D1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of DRD1 mRNA
CTD
PMID:18636392
NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
G
EEF2
eukaryotic translation elongation factor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EEF2 mRNA
CTD
PMID:18636392
NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
G
EGR1
early growth response 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of EGR1 mRNA
CTD
PMID:18636392
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
G
EIF2S1
eukaryotic translation initiation factor 2 subunit alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EIF2S1 mRNA
CTD
PMID:18636392
NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
G
EIF5
eukaryotic translation initiation factor 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of EIF5 mRNA
CTD
PMID:18636392
NCBI chr14:103,334,237...103,345,025
Ensembl chr14:103,333,544...103,345,025
G
F2
coagulation factor II, thrombin
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of F2 mRNA [Ozone co-treated with Chlorine] affects the expression of F2 mRNA
CTD
PMID:18636392
NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506
G
FAAH
fatty acid amide hydrolase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of FAAH mRNA
CTD
PMID:18636392
NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
G
FABP1
fatty acid binding protein 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FABP1 mRNA [Ozone co-treated with Chlorine] affects the expression of FABP1 mRNA
CTD
PMID:18636392
NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062
G
FABP2
fatty acid binding protein 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of FABP2 mRNA
CTD
PMID:18636392
NCBI chr 4:119,317,250...119,322,138
Ensembl chr 4:119,317,250...119,322,138
G
FABP4
fatty acid binding protein 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of FABP4 mRNA
CTD
PMID:18636392
NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
G
FABP5
fatty acid binding protein 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FABP5 mRNA
CTD
PMID:18636392
NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777
G
FAS
Fas cell surface death receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FAS mRNA
CTD
PMID:18636392
NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
G
FGF10
fibroblast growth factor 10
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FGF10 mRNA [Ozone co-treated with Chlorine] affects the expression of FGF10 mRNA
CTD
PMID:18636392
NCBI chr 5:44,300,247...44,389,420
Ensembl chr 5:44,300,247...44,389,706
G
FGF2
fibroblast growth factor 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of FGF2 mRNA Chlorine results in decreased expression of FGF2 mRNA
CTD
PMID:18636392
NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
G
FGR
FGR proto-oncogene, Src family tyrosine kinase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of FGR mRNA
CTD
PMID:18636392
NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
G
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of FOS mRNA [Ozone co-treated with Chlorine] affects the expression of FOS mRNA
CTD
PMID:18636392
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
G
FOSL1
FOS like 1, AP-1 transcription factor subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of FOSL1 mRNA
CTD
PMID:18636392
NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
G
GABBR1
gamma-aminobutyric acid type B receptor subunit 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GABBR1 mRNA [Ozone co-treated with Chlorine] results in increased expression of GABBR1 mRNA
CTD
PMID:18636392
NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976
G
GALR1
galanin receptor 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GALR1 mRNA [Ozone co-treated with Chlorine] results in increased expression of GALR1 mRNA
CTD
PMID:18636392
NCBI chr18:77,249,848...77,277,900
Ensembl chr18:77,249,848...77,277,900
G
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GAPDH mRNA
CTD
PMID:18636392
NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
G
GCGR
glucagon receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GCGR mRNA
CTD
PMID:18636392
NCBI chr17:81,804,150...81,814,008
Ensembl chr17:81,804,132...81,814,008
G
GCLM
glutamate-cysteine ligase modifier subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA
CTD
PMID:18636392
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
G
GDI1
GDP dissociation inhibitor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GDI1 mRNA
CTD
PMID:18636392
NCBI chr X:154,437,154...154,443,467
Ensembl chr X:154,436,913...154,443,467
G
GDI2
GDP dissociation inhibitor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GDI2 mRNA
CTD
PMID:18636392
NCBI chr10:5,765,223...5,813,434
Ensembl chr10:5,765,222...5,842,132
G
GHR
growth hormone receptor
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GHR mRNA Chlorine results in decreased expression of GHR mRNA
CTD
PMID:18636392
NCBI chr 5:42,423,439...42,721,878
Ensembl chr 5:42,423,439...42,721,878
G
GIPR
gastric inhibitory polypeptide receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GIPR mRNA
CTD
PMID:18636392
NCBI chr19:45,668,221...45,683,722
Ensembl chr19:45,668,221...45,683,722
G
GMFB
glia maturation factor beta
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA
CTD
PMID:18636392
NCBI chr14:54,474,485...54,488,980
Ensembl chr14:54,474,484...54,489,025
G
GNAI1
G protein subunit alpha i1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAI1 mRNA
CTD
PMID:18636392
NCBI chr 7:80,134,831...80,226,181
Ensembl chr 7:79,768,028...80,226,181
G
GNAI2
G protein subunit alpha i2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAI2 mRNA
CTD
PMID:18636392
NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362
G
GNAO1
G protein subunit alpha o1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of GNAO1 mRNA [Ozone co-treated with Chlorine] affects the expression of GNAO1 mRNA
CTD
PMID:18636392
NCBI chr16:56,191,489...56,357,444
Ensembl chr16:56,189,660...56,357,444
G
GNAS
GNAS complex locus
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNAS mRNA
CTD
PMID:18636392
NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192
G
GNAZ
G protein subunit alpha z
increases expression multiple interactions
ISO
Chlorine results in increased expression of GNAZ mRNA [Ozone co-treated with Chlorine] results in increased expression of GNAZ mRNA
CTD
PMID:18636392
NCBI chr22:23,070,519...23,125,032
Ensembl chr22:23,070,519...23,125,032
G
GNB1
G protein subunit beta 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GNB1 mRNA
CTD
PMID:18636392
NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
G
GPX3
glutathione peroxidase 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of GPX3 mRNA [Ozone co-treated with Chlorine] affects the expression of GPX3 mRNA
CTD
PMID:18636392
NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
G
GPX5
glutathione peroxidase 5
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GPX5 mRNA Chlorine results in increased expression of GPX5 mRNA
CTD
PMID:18636392
NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955
G
GRK3
G protein-coupled receptor kinase 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of GRK3 mRNA [Ozone co-treated with Chlorine] results in increased expression of GRK3 mRNA
CTD
PMID:18636392
NCBI chr22:25,564,675...25,729,294
Ensembl chr22:25,564,675...25,729,294
G
GSR
glutathione-disulfide reductase
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GSR mRNA
CTD
PMID:18636392
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSS
glutathione synthetase
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of GSS mRNA Chlorine results in increased expression of GSS mRNA
CTD
PMID:18636392
NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
G
GSTA4
glutathione S-transferase alpha 4
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GSTA4 mRNA Chlorine results in decreased expression of GSTA4 mRNA
CTD
PMID:18636392
NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304
G
GSTK1
glutathione S-transferase kappa 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of GSTK1 mRNA [Ozone co-treated with Chlorine] affects the expression of GSTK1 mRNA
CTD
PMID:18636392
NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
G
GSTM2
glutathione S-transferase mu 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of GSTM2 mRNA Chlorine results in decreased expression of GSTM2 mRNA
CTD
PMID:18636392
NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
G
GSTT2
glutathione S-transferase theta 2 (gene/pseudogene)
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of GSTT2 mRNA
CTD
PMID:18636392
NCBI chr22:23,980,134...23,983,915
Ensembl chr22:23,980,058...23,983,915
G
GUCY2D
guanylate cyclase 2D, retinal
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of GUCY2D mRNA
CTD
PMID:18636392
NCBI chr17:8,002,615...8,020,342
Ensembl chr17:8,002,615...8,020,342
G
H2AX
H2A.X variant histone
increases expression
ISO
Chlorine results in increased expression of H2AX protein
CTD
PMID:36690086
NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
G
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of HMGCS2 mRNA [Ozone co-treated with Chlorine] affects the expression of HMGCS2 mRNA
CTD
PMID:18636392
NCBI chr 1:119,747,996...119,768,932
Ensembl chr 1:119,748,002...119,768,905
G
HMOX1
heme oxygenase 1
increases expression
ISO
Chlorine results in increased expression of HMOX1 protein
CTD
PMID:36690086
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HMOX2
heme oxygenase 2
increases expression
EXP
Chlorine results in increased expression of HMOX2 protein
CTD
PMID:35065218
NCBI chr16:4,474,736...4,510,347
Ensembl chr16:4,474,690...4,510,347
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HPCAL4
hippocalcin like 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HPCAL4 mRNA
CTD
PMID:18636392
NCBI chr 1:39,678,648...39,691,433
Ensembl chr 1:39,678,648...39,691,485
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HPRT1
hypoxanthine phosphoribosyltransferase 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of HPRT1 mRNA [Ozone co-treated with Chlorine] affects the expression of HPRT1 mRNA
CTD
PMID:18636392
NCBI chr X:134,460,165...134,500,668
Ensembl chr X:134,460,165...134,520,513
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HRAS
HRas proto-oncogene, GTPase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of HRAS mRNA
CTD
PMID:18636392
NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
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HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of HSD3B1 mRNA [Ozone co-treated with Chlorine] affects the expression of HSD3B1 mRNA
CTD
PMID:18636392
NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
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HSPA5
heat shock protein family A (Hsp70) member 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA
CTD
PMID:18636392
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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HSPD1
heat shock protein family D (Hsp60) member 1
multiple interactions increases expression
ISO EXP
[Ozone co-treated with Chlorine] results in decreased expression of HSPD1 mRNA Chlorine results in increased expression of HSPD1 protein Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]
CTD
PMID:18636392 PMID:35065218
NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
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HTR1F
5-hydroxytryptamine receptor 1F
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HTR1F mRNA
CTD
PMID:18636392
NCBI chr 3:87,792,706...87,993,839
Ensembl chr 3:87,792,706...87,993,839
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HTR6
5-hydroxytryptamine receptor 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of HTR6 mRNA
CTD
PMID:18636392
NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966
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HTT
huntingtin
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of HTT mRNA
CTD
PMID:18636392
NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,363...3,243,957
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ID2
inhibitor of DNA binding 2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of ID2 mRNA Chlorine results in decreased expression of ID2 mRNA
CTD
PMID:18636392
NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461
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IFI16
interferon gamma inducible protein 16
increases expression
ISO
Chlorine results in increased expression of IFI204 mRNA
CTD
PMID:30189237
NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155
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IFNG
interferon gamma
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of IFNG mRNA Chlorine results in increased expression of IFNG protein
CTD
PMID:18636392 PMID:23146759
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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IGFALS
insulin like growth factor binding protein acid labile subunit
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of IGFALS mRNA
CTD
PMID:18636392
NCBI chr16:1,790,413...1,794,908
Ensembl chr16:1,790,413...1,794,971
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IGFBP3
insulin like growth factor binding protein 3
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of IGFBP3 mRNA [Ozone co-treated with Chlorine] affects the expression of IGFBP3 mRNA
CTD
PMID:18636392
NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
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IL12A
interleukin 12A
increases expression
ISO
Chlorine results in increased expression of IL12A protein
CTD
PMID:23146759
NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019
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IL12B
interleukin 12B
increases expression
ISO
Chlorine results in increased expression of IL12B protein
CTD
PMID:23146759
NCBI chr 5:159,314,780...159,330,487
Ensembl chr 5:159,314,780...159,330,863
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IL13
interleukin 13
increases expression
ISO
Chlorine results in increased expression of IL13 protein
CTD
PMID:23146759
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
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IL18
interleukin 18
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA
CTD
PMID:18636392
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096
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IL1B
interleukin 1 beta
multiple interactions affects expression increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of IL1B mRNA [Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein Chlorine affects the expression of IL1B mRNA Chlorine results in increased expression of IL1B protein
CTD
PMID:18636392 PMID:23146759 PMID:24582687 PMID:31066272
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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IL1RL1
interleukin 1 receptor like 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of IL1RL1 mRNA Chlorine results in decreased expression of IL1RL1 mRNA
CTD
PMID:18636392
NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037
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IL4R
interleukin 4 receptor
increases expression
ISO
Chlorine results in increased expression of IL4RA mRNA
CTD
PMID:30189237
NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778
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IL6
interleukin 6
increases expression multiple interactions decreases secretion
ISO EXP
Chlorine results in increased expression of IL6 mRNA; Chlorine results in increased expression of IL6 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]
CTD
PMID:23146759 PMID:30189237 PMID:35065218
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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INHBA
inhibin subunit beta A
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of INHBA mRNA
CTD
PMID:18636392
NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834
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INSRR
insulin receptor related receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of INSRR mRNA
CTD
PMID:18636392
NCBI chr 1:156,840,063...156,859,117
Ensembl chr 1:156,840,063...156,859,117
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ITGA1
integrin subunit alpha 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ITGA1 mRNA
CTD
PMID:18636392
NCBI chr 5:52,787,916...52,959,209
Ensembl chr 5:52,787,916...52,959,209
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ITGB1
integrin subunit beta 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ITGB1 mRNA
CTD
PMID:18636392
NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
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ITPR3
inositol 1,4,5-trisphosphate receptor type 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of ITPR3 mRNA
CTD
PMID:18636392
NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of JUN mRNA [Ozone co-treated with Chlorine] affects the expression of JUN mRNA
CTD
PMID:18636392
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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JUP
junction plakoglobin
increases expression multiple interactions
ISO
Chlorine results in increased expression of JUP mRNA [Ozone co-treated with Chlorine] results in decreased expression of JUP mRNA
CTD
PMID:18636392
NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
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KCNA4
potassium voltage-gated channel subfamily A member 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNA4 mRNA
CTD
PMID:18636392
NCBI chr11:30,009,730...30,017,030
Ensembl chr11:30,009,730...30,017,030
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KCNB1
potassium voltage-gated channel subfamily B member 1
affects expression multiple interactions
ISO
Chlorine affects the expression of KCNB1 mRNA [Ozone co-treated with Chlorine] affects the expression of KCNB1 mRNA
CTD
PMID:18636392
NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297
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KCND2
potassium voltage-gated channel subfamily D member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of KCND2 mRNA
CTD
PMID:18636392
NCBI chr 7:120,272,908...120,750,337
Ensembl chr 7:120,273,175...120,750,337
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KCNJ4
potassium inwardly rectifying channel subfamily J member 4
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of KCNJ4 mRNA [Ozone co-treated with Chlorine] results in decreased expression of KCNJ4 mRNA
CTD
PMID:18636392
NCBI chr22:38,426,327...38,455,199
Ensembl chr22:38,426,327...38,455,199
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KCNJ5
potassium inwardly rectifying channel subfamily J member 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNJ5 mRNA
CTD
PMID:18636392
NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
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KCNJ8
potassium inwardly rectifying channel subfamily J member 8
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of KCNJ8 mRNA
CTD
PMID:18636392
NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600
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KLKB1
kallikrein B1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of KLKB1 mRNA
CTD
PMID:18636392
NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471
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KRAS
KRAS proto-oncogene, GTPase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of KRAS mRNA
CTD
PMID:18636392
NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
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LCAT
lecithin-cholesterol acyltransferase
multiple interactions decreases expression
ISO EXP
[Ozone co-treated with Chlorine] affects the expression of LCAT mRNA [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein Chlorine results in decreased expression of LCAT mRNA
CTD
PMID:18636392 PMID:33861588
NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
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LIMK1
LIM domain kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of LIMK1 mRNA
CTD
PMID:18636392
NCBI chr 7:74,083,804...74,122,525
Ensembl chr 7:74,082,933...74,122,525
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LIPC
lipase C, hepatic type
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of LIPC mRNA [Ozone co-treated with Chlorine] results in increased expression of LIPC mRNA
CTD
PMID:18636392
NCBI chr15:58,431,991...58,569,844
Ensembl chr15:58,410,569...58,569,844
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LIPE
lipase E, hormone sensitive type
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of LIPE mRNA
CTD
PMID:18636392
NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,497...42,427,388
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LYN
LYN proto-oncogene, Src family tyrosine kinase
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of LYN mRNA Chlorine results in increased expression of LYN mRNA
CTD
PMID:18636392
NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169
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MAL
mal, T cell differentiation protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MAL mRNA
CTD
PMID:18636392
NCBI chr 2:95,025,708...95,053,992
Ensembl chr 2:95,025,677...95,053,992
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MAP2K1
mitogen-activated protein kinase kinase 1
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAP2K1 mRNA Chlorine results in increased expression of MAP2K1 mRNA
CTD
PMID:18636392
NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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MAPK1
mitogen-activated protein kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAPK1 mRNA
CTD
PMID:18636392
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3
mitogen-activated protein kinase 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAPK3 mRNA
CTD
PMID:18636392
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAX
MYC associated factor X
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MAX mRNA
CTD
PMID:18636392
NCBI chr14:65,006,101...65,102,695
Ensembl chr14:65,006,174...65,102,695
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MC4R
melanocortin 4 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MC4R mRNA
CTD
PMID:18636392
NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775
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MECP2
methyl-CpG binding protein 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MECP2 mRNA
CTD
PMID:18636392
NCBI chr X:154,021,573...154,097,717
Ensembl chr X:154,021,573...154,137,103
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MEOX2
mesenchyme homeobox 2
affects expression multiple interactions
ISO
Chlorine affects the expression of MEOX2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of MEOX2 mRNA
CTD
PMID:18636392
NCBI chr 7:15,611,212...15,686,683
Ensembl chr 7:15,611,212...15,686,683
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MGMT
O-6-methylguanine-DNA methyltransferase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MGMT mRNA
CTD
PMID:18636392
NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
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MGST1
microsomal glutathione S-transferase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of MGST1 mRNA [Ozone co-treated with Chlorine] affects the expression of MGST1 mRNA
CTD
PMID:18636392
NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
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MMP14
matrix metallopeptidase 14
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MMP14 mRNA
CTD
PMID:18636392
NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041
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MMP9
matrix metallopeptidase 9
decreases secretion increases expression multiple interactions
EXP ISO
Chlorine results in decreased secretion of MMP9 protein Chlorine results in increased expression of MMP9 protein Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]
CTD
PMID:35065218 PMID:36690086
NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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MPO
myeloperoxidase
multiple interactions
EXP
[MPO protein binds to and results in increased oxidation of APOA1 protein] promotes the reaction [APOA1 protein binds to Chlorine]; [MPO protein promotes the reaction [APOA1 protein binds to Chlorine]] which results in decreased activity of LCAT protein; MPO protein promotes the reaction [chlorodimedone binds to Chlorine]; Phenolsulfonphthalein promotes the reaction [MPO protein promotes the reaction [chlorodimedone binds to Chlorine]]
CTD
PMID:31288001 PMID:33861588
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MRC1
mannose receptor C-type 1
increases expression
ISO
Chlorine results in increased expression of MRC1 mRNA
CTD
PMID:30189237
NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164
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MRGPRF
MAS related GPR family member F
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of MRGPRF mRNA
CTD
PMID:18636392
NCBI chr11:69,004,398...69,013,633
Ensembl chr11:69,004,398...69,013,246
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MTNR1A
melatonin receptor 1A
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of MTNR1A mRNA [Ozone co-treated with Chlorine] results in increased expression of MTNR1A mRNA
CTD
PMID:18636392
NCBI chr 4:186,533,655...186,555,567
Ensembl chr 4:186,526,792...186,555,567
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MVP
major vault protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of MVP mRNA
CTD
PMID:18636392
NCBI chr16:29,820,394...29,848,039
Ensembl chr16:29,820,394...29,848,039
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MYO1B
myosin IB
increases expression multiple interactions
ISO
Chlorine results in increased expression of MYO1B mRNA [Ozone co-treated with Chlorine] affects the expression of MYO1B mRNA
CTD
PMID:18636392
NCBI chr 2:191,245,404...191,425,386
Ensembl chr 2:191,245,185...191,425,389
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NELL1
neural EGFL like 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NELL1 mRNA
CTD
PMID:18636392
NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
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NELL2
neural EGFL like 2
increases expression multiple interactions
ISO
Chlorine results in increased expression of NELL2 mRNA [Ozone co-treated with Chlorine] results in increased expression of NELL2 mRNA
CTD
PMID:18636392
NCBI chr12:44,508,275...44,921,848
Ensembl chr12:44,508,275...44,921,848
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NFKBIA
NFKB inhibitor alpha
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of NFKBIA mRNA Chlorine results in decreased expression of NFKBIA mRNA
CTD
PMID:18636392
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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NGB
neuroglobin
affects abundance
EXP
NGB protein affects the abundance of Chlorine
CTD
PMID:19154338
NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
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NME2
NME/NM23 nucleoside diphosphate kinase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NME2 mRNA
CTD
PMID:18636392
NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
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NOS1
nitric oxide synthase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NOS1 mRNA
CTD
PMID:18636392
NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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NOS2
nitric oxide synthase 2
increases expression
ISO
Chlorine results in increased expression of NOS2 mRNA
CTD
PMID:21131444
NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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NOS3
nitric oxide synthase 3
decreases activity decreases expression
ISO
Chlorine results in decreased activity of NOS3 protein Chlorine results in decreased expression of NOS3 protein
CTD
PMID:21131444
NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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NPPC
natriuretic peptide C
multiple interactions affects expression
ISO
[Ozone co-treated with Chlorine] affects the expression of NPPC mRNA Chlorine affects the expression of NPPC mRNA
CTD
PMID:18636392
NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396
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NPTXR
neuronal pentraxin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NPTXR mRNA
CTD
PMID:18636392
NCBI chr22:38,818,452...38,844,028
Ensembl chr22:38,818,452...38,844,028
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NR2C2
nuclear receptor subfamily 2 group C member 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NR2C2 mRNA [Ozone co-treated with Chlorine] affects the expression of NR2C2 mRNA
CTD
PMID:18636392
NCBI chr 3:14,947,583...15,049,273
Ensembl chr 3:14,947,583...15,053,600
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NR2F1
nuclear receptor subfamily 2 group F member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NR2F1 mRNA
CTD
PMID:18636392
NCBI chr 5:93,583,222...93,594,611
Ensembl chr 5:93,583,222...93,594,611
G
NR3C2
nuclear receptor subfamily 3 group C member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NR3C2 mRNA
CTD
PMID:18636392
NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698
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NR4A1
nuclear receptor subfamily 4 group A member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NR4A1 mRNA [Ozone co-treated with Chlorine] affects the expression of NR4A1 mRNA
CTD
PMID:18636392
NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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NR4A3
nuclear receptor subfamily 4 group A member 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of NR4A3 mRNA
CTD
PMID:18636392
NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891
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NRP2
neuropilin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of NRP2 mRNA
CTD
PMID:18636392
NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133
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NRXN1
neurexin 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NRXN1 mRNA
CTD
PMID:18636392
NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575
G
NRXN2
neurexin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NRXN2 mRNA
CTD
PMID:18636392
NCBI chr11:64,606,174...64,723,197
Ensembl chr11:64,606,174...64,723,197
G
NTRK1
neurotrophic receptor tyrosine kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of NTRK1 mRNA
CTD
PMID:18636392
NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,636...156,881,850
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NTSR2
neurotensin receptor 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of NTSR2 mRNA [Ozone co-treated with Chlorine] affects the expression of NTSR2 mRNA
CTD
PMID:18636392
NCBI chr 2:11,658,178...11,670,195
Ensembl chr 2:11,658,178...11,670,195
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ODC1
ornithine decarboxylase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of ODC1 mRNA
CTD
PMID:18636392
NCBI chr 2:10,439,968...10,448,327
Ensembl chr 2:10,439,968...10,448,327
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OPRK1
opioid receptor kappa 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of OPRK1 mRNA Chlorine results in decreased expression of OPRK1 mRNA
CTD
PMID:18636392
NCBI chr 8:53,225,724...53,251,637
Ensembl chr 8:53,225,724...53,251,637
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PAK1
p21 (RAC1) activated kinase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PAK1 mRNA
CTD
PMID:18636392
NCBI chr11:77,322,017...77,530,009
Ensembl chr11:77,322,017...77,474,635
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PCNA
proliferating cell nuclear antigen
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PCNA mRNA
CTD
PMID:18636392
NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626
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PCSK7
proprotein convertase subtilisin/kexin type 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PCSK7 mRNA
CTD
PMID:18636392
NCBI chr11:117,204,337...117,232,073
Ensembl chr11:117,204,337...117,232,525
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PDAP1
PDGFA associated protein 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PDAP1 mRNA
CTD
PMID:18636392
NCBI chr 7:99,394,673...99,408,597
Ensembl chr 7:99,392,048...99,408,597
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PDE4D
phosphodiesterase 4D
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PDE4D mRNA
CTD
PMID:18636392
NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
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PDGFRB
platelet derived growth factor receptor beta
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PDGFRB mRNA
CTD
PMID:18636392
NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
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PDIA4
protein disulfide isomerase family A member 4
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PDIA4 mRNA Chlorine results in increased expression of PDIA4 mRNA
CTD
PMID:18636392
NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662
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PDLIM1
PDZ and LIM domain 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PDLIM1 mRNA
CTD
PMID:18636392
NCBI chr10:95,237,572...95,291,003
Ensembl chr10:95,237,572...95,291,012
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PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PFKFB4 mRNA
CTD
PMID:18636392
NCBI chr 3:48,517,684...48,563,136
Ensembl chr 3:48,517,684...48,562,015
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PGAP2
post-GPI attachment to proteins 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PGAP2 mRNA
CTD
PMID:18636392
NCBI chr11:3,797,724...3,826,371
Ensembl chr11:3,797,724...3,826,371
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PHB1
prohibitin 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of PHB1 mRNA [Ozone co-treated with Chlorine] results in increased expression of PHB1 mRNA
CTD
PMID:18636392
NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
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PI4KA
phosphatidylinositol 4-kinase alpha
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of PI4KA mRNA [Ozone co-treated with Chlorine] affects the expression of PI4KA mRNA
CTD
PMID:18636392
NCBI chr22:20,707,691...20,858,811
Ensembl chr22:20,707,691...20,859,417
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PLA2G2C
phospholipase A2 group IIC
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PLA2G2C mRNA
CTD
PMID:18636392
NCBI chr 1:20,163,055...20,186,518
Ensembl chr 1:20,161,253...20,186,518
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PLAC8
placenta associated 8
increases expression
ISO
Chlorine results in increased expression of PLAC8 mRNA
CTD
PMID:30189237
NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,059,493...83,137,075
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PLAT
plasminogen activator, tissue type
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNA
CTD
PMID:18636392
NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
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PLEC
plectin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA
CTD
PMID:18636392
NCBI chr 8:143,915,153...143,976,745
Ensembl chr 8:143,915,153...143,976,734
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PLPP1
phospholipid phosphatase 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PLPP1 mRNA Chlorine results in decreased expression of PLPP1 mRNA
CTD
PMID:18636392
NCBI chr 5:55,424,854...55,534,964
Ensembl chr 5:55,424,854...55,534,969
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PMP22
peripheral myelin protein 22
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PMP22 mRNA
CTD
PMID:18636392
NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292
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PNLIP
pancreatic lipase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of PNLIP mRNA
CTD
PMID:18636392
NCBI chr10:116,545,931...116,567,855
Ensembl chr10:116,545,931...116,567,855
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PPP2CA
protein phosphatase 2 catalytic subunit alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PPP2CA mRNA
CTD
PMID:18636392
NCBI chr 5:134,194,332...134,226,073
Ensembl chr 5:134,193,978...134,226,073
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PPP2CB
protein phosphatase 2 catalytic subunit beta
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PPP2CB mRNA
CTD
PMID:18636392
NCBI chr 8:30,785,616...30,812,818
Ensembl chr 8:30,774,457...30,814,314
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PRDX2
peroxiredoxin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PRDX2 mRNA
CTD
PMID:18636392
NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
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PRMT1
protein arginine methyltransferase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PRMT1 mRNA
CTD
PMID:18636392
NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029
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PSMA1
proteasome 20S subunit alpha 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA1 mRNA
CTD
PMID:18636392
NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,211...14,643,635
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PSMA2
proteasome 20S subunit alpha 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA2 mRNA
CTD
PMID:18636392
NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,916,828...42,932,185
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PSMA3
proteasome 20S subunit alpha 3
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMA3L mRNA [Ozone co-treated with Chlorine] affects the expression of PSMA3L mRNA
CTD
PMID:18636392
NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012
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PSMA4
proteasome 20S subunit alpha 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMA4 mRNA
CTD
PMID:18636392
NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417
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PSMB3
proteasome 20S subunit beta 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB3 mRNA
CTD
PMID:18636392
NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
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PSMB4
proteasome 20S subunit beta 4
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMB4 mRNA [Ozone co-treated with Chlorine] affects the expression of PSMB4 mRNA
CTD
PMID:18636392
NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937
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PSMB6
proteasome 20S subunit beta 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB6 mRNA
CTD
PMID:18636392
NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502
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PSMB8
proteasome 20S subunit beta 8
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA
CTD
PMID:18636392
NCBI chr 6:32,840,717...32,844,679
Ensembl chr 6:32,840,717...32,844,679
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PSMC1
proteasome 26S subunit, ATPase 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMC1 mRNA
CTD
PMID:18636392
NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
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PSMC2
proteasome 26S subunit, ATPase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PSMC2 mRNA
CTD
PMID:18636392
NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
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PSMC4
proteasome 26S subunit, ATPase 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PSMC4 mRNA
CTD
PMID:18636392
NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
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PSMC5
proteasome 26S subunit, ATPase 5
increases expression multiple interactions
ISO
Chlorine results in increased expression of PSMC5 mRNA [Ozone co-treated with Chlorine] affects the expression of PSMC5 mRNA
CTD
PMID:18636392
NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026
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PTAFR
platelet activating factor receptor
increases expression multiple interactions
ISO
Chlorine results in increased expression of PTAFR mRNA [Ozone co-treated with Chlorine] affects the expression of PTAFR mRNA
CTD
PMID:18636392
NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936
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PTGS2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Chlorine results in increased expression of PTGS2 mRNA
CTD
PMID:24582687
NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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PTN
pleiotrophin
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of PTN mRNA Chlorine results in increased expression of PTN mRNA
CTD
PMID:18636392
NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
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PTPN11
protein tyrosine phosphatase non-receptor type 11
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of PTPN11 mRNA
CTD
PMID:18636392
NCBI chr12:112,418,947...112,509,918
Ensembl chr12:112,418,351...112,509,918
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PTPN7
protein tyrosine phosphatase non-receptor type 7
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of PTPN7 mRNA
CTD
PMID:18636392
NCBI chr 1:202,147,013...202,161,588
Ensembl chr 1:202,147,012...202,161,588
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PTPRR
protein tyrosine phosphatase receptor type R
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of PTPRR mRNA [Ozone co-treated with Chlorine] affects the expression of PTPRR mRNA
CTD
PMID:18636392
NCBI chr12:70,638,073...70,920,738
Ensembl chr12:70,638,073...70,920,738
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RAB15
RAB15, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB15 mRNA [Ozone co-treated with Chlorine] affects the expression of RAB15 mRNA
CTD
PMID:18636392
NCBI chr14:64,945,816...64,972,336
Ensembl chr14:64,945,814...64,973,226
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RAB1A
RAB1A, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB1A mRNA [Ozone co-treated with Chlorine] affects the expression of RAB1A mRNA
CTD
PMID:18636392
NCBI chr 2:65,086,854...65,130,106
Ensembl chr 2:65,070,696...65,130,331
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RAB2A
RAB2A, member RAS oncogene family
increases expression multiple interactions
ISO
Chlorine results in increased expression of RAB2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of RAB2 mRNA
CTD
PMID:18636392
NCBI chr 8:60,516,910...60,623,644
Ensembl chr 8:60,516,936...60,623,644
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RAB3B
RAB3B, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RAB3B mRNA
CTD
PMID:18636392
NCBI chr 1:51,907,956...51,990,700
Ensembl chr 1:51,907,956...51,990,700
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RAB3D
RAB3D, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RAB3D mRNA
CTD
PMID:18636392
NCBI chr19:11,322,068...11,339,657
Ensembl chr19:11,322,068...11,346,270
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RAB4A
RAB4A, member RAS oncogene family
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RAB4A mRNA
CTD
PMID:18636392
NCBI chr 1:229,271,111...229,305,894
Ensembl chr 1:229,271,062...229,305,894
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RALA
RAS like proto-oncogene A
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of RALA mRNA
CTD
PMID:18636392
NCBI chr 7:39,623,572...39,708,120
Ensembl chr 7:39,623,565...39,708,120
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RALGDS
ral guanine nucleotide dissociation stimulator
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of RALGDS mRNA Chlorine results in increased expression of RALGDS mRNA
CTD
PMID:18636392
NCBI chr 9:133,097,722...133,149,210
Ensembl chr 9:133,097,720...133,149,334
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RASA1
RAS p21 protein activator 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RASA1 mRNA
CTD
PMID:18636392
NCBI chr 5:87,267,883...87,391,916
Ensembl chr 5:87,267,883...87,391,931
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RIMS1
regulating synaptic membrane exocytosis 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of RIMS1 mRNA
CTD
PMID:18636392
NCBI chr 6:71,886,550...72,403,145
Ensembl chr 6:71,886,550...72,403,150
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RIN1
Ras and Rab interactor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RIN1 mRNA
CTD
PMID:18636392
NCBI chr11:66,330,241...66,336,774
Ensembl chr11:66,330,241...66,336,840
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RNPEP
arginyl aminopeptidase
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RNPEP mRNA
CTD
PMID:18636392
NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147
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RPL10
ribosomal protein L10
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL10 mRNA
CTD
PMID:18636392
NCBI chr X:154,398,065...154,402,339
Ensembl chr X:154,389,955...154,409,168
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RPL11
ribosomal protein L11
increases expression multiple interactions
ISO
Chlorine results in increased expression of RPL11 mRNA [Ozone co-treated with Chlorine] affects the expression of RPL11 mRNA
CTD
PMID:18636392
NCBI chr 1:23,691,779...23,696,835
Ensembl chr 1:23,691,742...23,696,835
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RPL12
ribosomal protein L12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL12 mRNA
CTD
PMID:18636392
NCBI chr 9:127,447,674...127,451,406
Ensembl chr 9:127,447,674...127,451,406
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RPL13
ribosomal protein L13
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL13 mRNA
CTD
PMID:18636392
NCBI chr16:89,560,657...89,566,829
Ensembl chr16:89,560,677...89,567,834
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RPL21
ribosomal protein L21
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL21 mRNA
CTD
PMID:18636392
NCBI chr13:27,251,558...27,256,568
Ensembl chr13:27,251,362...27,259,609
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RPL36AL
ribosomal protein L36a like
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPL36AL mRNA
CTD
PMID:18636392
NCBI chr14:49,618,530...49,620,626
Ensembl chr14:49,618,530...49,620,626
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RPS11
ribosomal protein S11
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS11 mRNA
CTD
PMID:18636392
NCBI chr19:49,496,434...49,499,708
Ensembl chr19:49,496,365...49,499,708
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RPS12
ribosomal protein S12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS12 mRNA
CTD
PMID:18636392
NCBI chr 6:132,814,569...132,817,564
Ensembl chr 6:132,814,569...132,817,564
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RPS17
ribosomal protein S17
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS17 mRNA
CTD
PMID:18636392
NCBI chr15:82,536,750...82,540,457
Ensembl chr15:82,536,750...82,540,459
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RPS19
ribosomal protein S19
increases expression multiple interactions
ISO
Chlorine results in increased expression of RPS19 mRNA [Ozone co-treated with Chlorine] affects the expression of RPS19 mRNA
CTD
PMID:18636392
NCBI chr19:41,860,255...41,872,925
Ensembl chr19:41,860,255...41,872,925
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RPS29
ribosomal protein S29
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of RPS29 mRNA
CTD
PMID:18636392
NCBI chr14:49,570,988...49,598,710
Ensembl chr14:49,570,984...49,599,164
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RPS4X
ribosomal protein S4 X-linked
increases expression multiple interactions
ISO
Chlorine results in increased expression of RPS4X mRNA [Ozone co-treated with Chlorine] results in decreased expression of RPS4X mRNA
CTD
PMID:18636392
NCBI chr X:72,272,042...72,277,248
Ensembl chr X:72,255,679...72,277,248
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S1PR2
sphingosine-1-phosphate receptor 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of S1PR2 mRNA [Ozone co-treated with Chlorine] results in decreased expression of S1PR2 mRNA
CTD
PMID:18636392
NCBI chr19:10,221,433...10,231,331
Ensembl chr19:10,221,433...10,231,331
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SCN2B
sodium voltage-gated channel beta subunit 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SCN2B mRNA [Ozone co-treated with Chlorine] affects the expression of SCN2B mRNA
CTD
PMID:18636392
NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
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SCN4A
sodium voltage-gated channel alpha subunit 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SCN4A mRNA
CTD
PMID:18636392
NCBI chr17:63,938,554...63,972,918
Ensembl chr17:63,938,554...63,972,918
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SCP2
sterol carrier protein 2
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SCP2 mRNA [Ozone co-treated with Chlorine] affects the expression of SCP2 mRNA
CTD
PMID:18636392
NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
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SCTR
secretin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SCTR mRNA
CTD
PMID:18636392
NCBI chr 2:119,439,843...119,524,483
Ensembl chr 2:119,439,843...119,525,301
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SELP
selectin P
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SELP mRNA
CTD
PMID:18636392
NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193
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SERPINB2
serpin family B member 2
increases expression
ISO
Chlorine results in increased expression of SERPINB2 mRNA
CTD
PMID:30189237
NCBI chr18:63,887,705...63,903,888
Ensembl chr18:63,871,692...63,903,888
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SERPINB5
serpin family B member 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SERPINB5 mRNA
CTD
PMID:18636392
NCBI chr18:63,476,958...63,505,085
Ensembl chr18:63,476,958...63,505,085
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SERPINE1
serpin family E member 1
increases expression multiple interactions
ISO
Chlorine results in increased expression of SERPINE1 mRNA [Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNA
CTD
PMID:18636392
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SFTPB
surfactant protein B
affects expression
ISO
Chlorine affects the expression of SFTPB protein
CTD
PMID:24582687
NCBI chr 2:85,657,307...85,668,741
Ensembl chr 2:85,657,314...85,668,741
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SFTPD
surfactant protein D
affects expression increases expression
ISO
Chlorine affects the expression of SFTPD protein Chlorine results in increased expression of SFTPD protein
CTD
PMID:24582687 PMID:36690086
NCBI chr10:79,937,740...79,982,383
Ensembl chr10:79,937,467...79,982,614
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SGK1
serum/glucocorticoid regulated kinase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SGK1 mRNA [Ozone co-treated with Chlorine] results in increased expression of SGK1 mRNA
CTD
PMID:18636392
NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112
G
SIGLEC1
sialic acid binding Ig like lectin 1
increases expression
ISO
Chlorine results in increased expression of SIGLEC1 mRNA
CTD
PMID:30189237
NCBI chr20:3,686,970...3,712,600
Ensembl chr20:3,686,970...3,712,600
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SIRPA
signal regulatory protein alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SIRPA mRNA
CTD
PMID:18636392
NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592
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SLC10A1
solute carrier family 10 member 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SLC10A1 mRNA [Ozone co-treated with Chlorine] affects the expression of SLC10A1 mRNA
CTD
PMID:18636392
NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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SLC14A2
solute carrier family 14 member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC14A2 mRNA
CTD
PMID:18636392
NCBI chr18:45,167,963...45,683,688
Ensembl chr18:45,212,995...45,683,688
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SLC15A1
solute carrier family 15 member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC15A1 mRNA
CTD
PMID:18636392
NCBI chr13:98,683,801...98,752,672
Ensembl chr13:98,683,801...98,752,672
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SLC15A4
solute carrier family 15 member 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC15A4 mRNA
CTD
PMID:18636392
NCBI chr12:128,793,194...128,823,958
Ensembl chr12:128,793,194...128,823,958
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SLC16A1
solute carrier family 16 member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC16A1 mRNA
CTD
PMID:18636392
NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
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SLC17A1
solute carrier family 17 member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC17A1 mRNA
CTD
PMID:18636392
NCBI chr 6:25,723,743...25,832,052
Ensembl chr 6:25,782,915...25,832,052
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SLC18A1
solute carrier family 18 member A1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC18A1 mRNA
CTD
PMID:18636392
NCBI chr 8:20,144,855...20,183,136
Ensembl chr 8:20,144,855...20,183,206
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SLC1A6
solute carrier family 1 member 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SLC1A6 mRNA
CTD
PMID:18636392
NCBI chr19:14,950,033...15,010,643
Ensembl chr19:14,950,033...15,022,990
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SLC22A1
solute carrier family 22 member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC22A1 mRNA
CTD
PMID:18636392
NCBI chr 6:160,121,815...160,158,718
Ensembl chr 6:160,121,815...160,158,718
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SLC22A12
solute carrier family 22 member 12
multiple interactions
EXP
[Chlorine co-treated with perfluoro-n-heptanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluoro-n-nonanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorodecanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; [Chlorine co-treated with perfluorooctanoic acid] inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of perfluorooctanoic acid]; Chlorine inhibits the reaction [SLC22A12 protein results in increased import of Uric Acid]
CTD
PMID:20639259
NCBI chr11:64,591,220...64,602,344
Ensembl chr11:64,590,641...64,602,353
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SLC22A2
solute carrier family 22 member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC22A2 mRNA
CTD
PMID:18636392
NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
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SLC4A2
solute carrier family 4 member 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC4A2 mRNA
CTD
PMID:18636392
NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526
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SLC6A12
solute carrier family 6 member 12
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC6A12 mRNA
CTD
PMID:18636392
NCBI chr12:183,848...214,157
Ensembl chr12:190,077...214,570
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SLC6A15
solute carrier family 6 member 15
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC6A15 mRNA
CTD
PMID:18636392
NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629
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SLC6A9
solute carrier family 6 member 9
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC6A9 mRNA
CTD
PMID:18636392
NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
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SLC7A1
solute carrier family 7 member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SLC7A1 mRNA
CTD
PMID:18636392
NCBI chr13:29,509,414...29,595,688
Ensembl chr13:29,509,414...29,595,688
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SLC9A2
solute carrier family 9 member A2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLC9A2 mRNA
CTD
PMID:18636392
NCBI chr 2:102,619,553...102,711,355
Ensembl chr 2:102,619,553...102,711,355
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SLCO1A2
solute carrier organic anion transporter family member 1A2
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of SLCO1A4 mRNA Chlorine results in decreased expression of SLCO1A4 mRNA
CTD
PMID:18636392
NCBI chr12:21,264,600...21,419,634
Ensembl chr12:21,264,600...21,419,594
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SLPI
secretory leukocyte peptidase inhibitor
increases expression
ISO
Chlorine results in increased expression of SLPI mRNA
CTD
PMID:30189237
NCBI chr20:45,252,239...45,254,564
Ensembl chr20:45,252,239...45,254,564
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SMAD1
SMAD family member 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SMAD1 mRNA
CTD
PMID:18636392
NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176
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SMN1
survival of motor neuron 1, telomeric
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of SMN1 mRNA
CTD
PMID:18636392
NCBI chr 5:70,924,941...70,966,375
Ensembl chr 5:70,925,030...70,953,942 Ensembl chr 5:70,925,030...70,953,942
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SNAP25
synaptosome associated protein 25
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SNAP25 mRNA
CTD
PMID:18636392
NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258
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SPON1
spondin 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA
CTD
PMID:18636392
NCBI chr11:13,962,723...14,268,133
Ensembl chr11:13,962,723...14,268,133
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SSRP1
structure specific recognition protein 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SSRP1 mRNA
CTD
PMID:18636392
NCBI chr11:57,325,988...57,335,892
Ensembl chr11:57,325,986...57,335,892
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SST
somatostatin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SST mRNA
CTD
PMID:18636392
NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394
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SSTR3
somatostatin receptor 3
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of SSTR3 mRNA
CTD
PMID:18636392
NCBI chr22:37,204,237...37,220,548
Ensembl chr22:37,204,237...37,212,477
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STX1B
syntaxin 1B
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX1B mRNA
CTD
PMID:18636392
NCBI chr16:30,989,256...31,010,638
Ensembl chr16:30,989,256...31,010,638
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STX5
syntaxin 5
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX5A mRNA
CTD
PMID:18636392
NCBI chr11:62,806,860...62,832,051
Ensembl chr11:62,806,860...62,832,051
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STX6
syntaxin 6
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of STX6 mRNA
CTD
PMID:18636392
NCBI chr 1:180,972,725...181,022,870
Ensembl chr 1:180,972,712...181,023,121
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SULT1B1
sulfotransferase family 1B member 1
multiple interactions decreases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of SULT1B1 mRNA Chlorine results in decreased expression of SULT1B1 mRNA
CTD
PMID:18636392
NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961
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SV2B
synaptic vesicle glycoprotein 2B
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] results in increased expression of SV2B mRNA Chlorine results in increased expression of SV2B mRNA
CTD
PMID:18636392
NCBI chr15:91,099,588...91,302,565
Ensembl chr15:91,099,950...91,302,565
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SYP
synaptophysin
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYP mRNA
CTD
PMID:18636392
NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
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SYT11
synaptotagmin 11
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of SYT11 mRNA [Ozone co-treated with Chlorine] results in decreased expression of SYT11 mRNA
CTD
PMID:18636392
NCBI chr 1:155,859,567...155,885,199
Ensembl chr 1:155,859,567...155,885,199
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SYT2
synaptotagmin 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYT2 mRNA
CTD
PMID:18636392
NCBI chr 1:202,590,596...202,710,454
Ensembl chr 1:202,590,596...202,710,454
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SYT4
synaptotagmin 4
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of SYT4 mRNA
CTD
PMID:18636392
NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
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TACR2
tachykinin receptor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of TACR2 mRNA
CTD
PMID:18636392
NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918
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TAP2
transporter 2, ATP binding cassette subfamily B member
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TAP2 mRNA
CTD
PMID:18636392
NCBI chr 6:32,821,831...32,838,739
Ensembl chr 6:32,821,833...32,838,739
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TBXA2R
thromboxane A2 receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in increased expression of TBXA2R mRNA
CTD
PMID:18636392
NCBI chr19:3,594,507...3,606,875
Ensembl chr19:3,594,507...3,606,875
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TFRC
transferrin receptor
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TFRC mRNA
CTD
PMID:18636392
NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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TGFBR1
transforming growth factor beta receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of TGFBR1 mRNA
CTD
PMID:18636392
NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
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TIMP1
TIMP metallopeptidase inhibitor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA
CTD
PMID:18636392
NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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TK1
thymidine kinase 1
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of TK1 mRNA [Ozone co-treated with Chlorine] affects the expression of TK1 mRNA
CTD
PMID:18636392
NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233
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TNF
tumor necrosis factor
increases expression
ISO
Chlorine results in increased expression of TNF protein
CTD
PMID:23146759
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF1A
TNF receptor superfamily member 1A
increases expression
EXP
Chlorine results in increased expression of TNFRSF1A protein
CTD
PMID:35065218
NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
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TOP2A
DNA topoisomerase II alpha
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TOP2A mRNA
CTD
PMID:18636392
NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
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TP53
tumor protein p53
multiple interactions increases expression
EXP
Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form]
CTD
PMID:35065218
NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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TPP2
tripeptidyl peptidase 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TPP2 mRNA
CTD
PMID:18636392
NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958
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TUBA1A
tubulin alpha 1a
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of TUBA1A mRNA
CTD
PMID:18636392
NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,324
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TYMS
thymidylate synthetase
decreases expression multiple interactions
ISO
Chlorine results in decreased expression of TYMS mRNA [Ozone co-treated with Chlorine] affects the expression of TYMS mRNA
CTD
PMID:18636392
NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
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UNC5B
unc-5 netrin receptor B
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of UNC5B mRNA
CTD
PMID:18636392
NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864
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VCP
valosin containing protein
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of VCP mRNA
CTD
PMID:18636392
NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
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VHL
von Hippel-Lindau tumor suppressor
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VHL mRNA
CTD
PMID:18636392
NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676
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VIPR1
vasoactive intestinal peptide receptor 1
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VIPR1 mRNA
CTD
PMID:18636392
NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573
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VIPR2
vasoactive intestinal peptide receptor 2
multiple interactions
ISO
[Ozone co-treated with Chlorine] affects the expression of VIPR2 mRNA
CTD
PMID:18636392
NCBI chr 7:159,028,175...159,144,867
Ensembl chr 7:159,028,175...159,144,867
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YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of YWHAE mRNA
CTD
PMID:18636392
NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222
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YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
multiple interactions increases expression
ISO
[Ozone co-treated with Chlorine] affects the expression of YWHAG mRNA Chlorine results in increased expression of YWHAG mRNA
CTD
PMID:18636392
NCBI chr 7:76,326,799...76,358,991
Ensembl chr 7:76,326,799...76,358,991
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YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
multiple interactions
ISO
[Ozone co-treated with Chlorine] results in decreased expression of YWHAH mRNA
CTD
PMID:18636392
NCBI chr22:31,944,535...31,957,603
Ensembl chr22:31,944,522...31,957,603
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YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
increases expression multiple interactions
ISO
Chlorine results in increased expression of YWHAZ mRNA [Ozone co-treated with Chlorine] results in decreased expression of YWHAZ mRNA
CTD
PMID:18636392
NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
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