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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:elemental chlorine
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Accession:CHEBI:33431 term browser browse the term


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ammonium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]] CTD PMID:34520801 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SOX5 SRY-box transcription factor 5 multiple interactions EXP Ammonium Chloride inhibits the reaction [SOX5 protein inhibits the reaction [Warfarin results in increased expression of RUNX2 mRNA]] CTD PMID:34520801 NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,504,551...50,161,558 		JBrowse link
calcium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENPEP glutamyl aminopeptidase multiple interactions EXP Calcium Chloride promotes the reaction [ENPEP protein results in increased hydrolysis of Aspartame] CTD PMID:8141778 NCBI chr 8:111,765,839...111,858,349
Ensembl chr 8:111,748,514...111,858,510 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [Sodium Bicarbonate co-treated with Calcium Chloride] results in increased activity of GAPDH protein CTD PMID:26582256 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
cobalt dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 affects binding EXP cobaltous chloride binds to AOC1 protein CTD PMID:16842785 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 increases expression EXP cobaltous chloride results in increased expression of HSP90B1 mRNA CTD PMID:17464326 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP cobaltous chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
colforsin daropate hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 decreases activity EXP Colforsin results in decreased activity of ADCYAP1 protein alternative form CTD PMID:16847435 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294 		JBrowse link
G ATP7B ATPase copper transporting beta multiple interactions EXP Colforsin inhibits the reaction [Copper binds to ATP7B protein] CTD PMID:21084060 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064 		JBrowse link
G CFTR CF transmembrane conductance regulator increases activity EXP Colforsin results in increased activity of CFTR protein CTD PMID:15246976 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation		 EXP N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein] CTD PMID:17680988 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728 		JBrowse link
copper(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOC1 amine oxidase copper containing 1 increases activity EXP cupric chloride results in increased activity of AOC1 protein CTD PMID:16842785 NCBI chr18:6,309,583...6,321,016
Ensembl chr18:6,309,594...6,320,974 		JBrowse link
dichlorine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type decreases expression EXP Chlorine results in decreased expression of ALOX12 mRNA CTD PMID:22533443 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression EXP Chlorine results in increased expression of CCL2 mRNA CTD PMID:22533443 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression EXP Chlorine results in increased expression of CCR1 mRNA CTD PMID:22533443 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression EXP Chlorine results in increased expression of CXCL8 mRNA CTD PMID:22533443 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G EDN1 endothelin 1 increases expression EXP Chlorine results in increased expression of EDN1 protein CTD PMID:16625121 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 decreases expression EXP Chlorine results in decreased expression of FGFR2 mRNA CTD PMID:22533443 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Chlorine results in increased expression of FOS mRNA CTD PMID:22533443 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 increases expression EXP Chlorine results in increased expression of ICAM1 mRNA CTD PMID:22533443 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G IL1A interleukin 1 alpha decreases expression EXP Chlorine results in decreased expression of IL1A mRNA CTD PMID:22533443 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 increases expression EXP Chlorine results in increased expression of IL1R1 mRNA CTD PMID:22533443 NCBI chr 3:52,192,912...52,334,734
Ensembl chr 3:52,192,915...52,288,485 		JBrowse link
G IL6 interleukin 6 increases expression EXP Chlorine results in increased expression of IL6 mRNA CTD PMID:22533443 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP Chlorine results in increased expression of IL1B mRNA CTD PMID:22533443
G SELE selectin E increases expression EXP Chlorine results in increased expression of SELE mRNA CTD PMID:22533443 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G TNFRSF12A TNF receptor superfamily member 12A increases expression EXP Chlorine results in increased expression of TNFRSF12A mRNA CTD PMID:22533443 NCBI chr 3:39,166,288...39,168,294
Ensembl chr 3:39,166,298...39,168,302 		JBrowse link
methoctramine tetrahydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions EXP methoctramine inhibits the reaction [Quinuclidinyl Benzilate binds to CHRM2 protein] CTD PMID:8744975 NCBI chr18:12,455,139...12,600,314
Ensembl chr18:12,455,145...12,600,186 		JBrowse link
zinc dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PSP-I porcine seminal protein I multiple interactions
affects folding		 EXP zinc chloride promotes the reaction [PSP-I protein binds to Heparin]
zinc chloride affects the folding of PSP-I protein		 CTD PMID:16819821 NCBI chr14:132,302,376...132,309,388
Ensembl chr14:132,302,352...132,308,106 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5152
    chemical entity 5152
      molecular entity 5151
        elemental molecular entity 159
          elemental halogen 61
            elemental chlorine 27
              diatomic chlorine + 14
              monoatomic chlorine + 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 5152
    subatomic particle 5143
      composite particle 5143
        hadron 5143
          baryon 5143
            nucleon 5143
              atomic nucleus 5143
                atom 5143
                  main group element atom 5116
                    main group molecular entity 5115
                      p-block molecular entity 5113
                        halogen molecular entity 336
                          chlorine molecular entity 286
                            elemental chlorine 27
                              diatomic chlorine + 14
                              monoatomic chlorine + 13
paths to the root