CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: halogen oxoacid
Accession: CHEBI:33425
browse the term
Synonyms: related_synonym: halogen oxoacids
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Car1
carbonic anhydrase 1
decreases activity
ISO
chloric acid results in decreased activity of CA1 protein
CTD
PMID:15664814
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
chloric acid results in decreased activity of CA2 protein
CTD
PMID:15664814
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car4
carbonic anhydrase 4
decreases activity
ISO
chloric acid results in decreased activity of CA4 protein
CTD
PMID:15664814
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Car5a
carbonic anhydrase 5A
decreases activity
ISO
chloric acid results in decreased activity of CA5A protein
CTD
PMID:15664814
NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
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Car9
carbonic anhydrase 9
decreases activity
ISO
chloric acid results in decreased activity of CA9 protein
CTD
PMID:15664814
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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Cat
catalase
decreases activity
ISO
chloric acid results in decreased activity of CAT protein
CTD
PMID:21569832
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Gsr
glutathione-disulfide reductase
decreases activity
ISO
chloric acid results in decreased activity of GSR protein
CTD
PMID:21569832
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ABCC1 mRNA
CTD
PMID:19376150
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcd1
ATP binding cassette subfamily D member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABCD1 mRNA
CTD
PMID:19376150
NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115
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Abhd16a
abhydrolase domain containing 16A, phospholipase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABHD16A mRNA
CTD
PMID:19376150
NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927
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Acads
acyl-CoA dehydrogenase short chain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACADS mRNA
CTD
PMID:19376150
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acbd4
acyl-CoA binding domain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACBD4 mRNA
CTD
PMID:19376150
NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500
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Ache
acetylcholinesterase
multiple interactions decreases activity
ISO
[Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein; Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein]
CTD
PMID:12414318 PMID:36924976
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Adrm1
ADRM1 26S proteasome ubiquitin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of ADRM1 mRNA
CTD
PMID:19376150
NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
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Afp
alpha-fetoprotein
increases expression
ISO
Hypochlorous Acid results in increased expression of AFP mRNA
CTD
PMID:19376150
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agrn
agrin
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AGRN mRNA
CTD
PMID:19376150
NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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Akr1a1
aldo-keto reductase family 1 member A1
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1A1 mRNA
CTD
PMID:19376150
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1B1 mRNA
CTD
PMID:19376150
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr7a2
aldo-keto reductase family 7, member A2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AKR7A5 mRNA
CTD
PMID:19376150
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
Hypochlorous Acid results in increased expression of ALDH1A3 mRNA
CTD
PMID:18156441
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Amotl1
angiomotin-like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AMOTL1 mRNA
CTD
PMID:19376150
NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
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Ampd1
adenosine monophosphate deaminase 1
increases activity multiple interactions
ISO
Hypochlorous Acid results in increased activity of AMPD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein]
CTD
PMID:36924976
NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
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Angel2
angel homolog 2
increases expression
ISO
Hypochlorous Acid results in increased expression of ANGEL2 mRNA
CTD
PMID:19376150
NCBI chr13:102,509,111...102,529,501
Ensembl chr13:102,510,589...102,529,493
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Ankib1
ankyrin repeat and IBR domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ANKIB1 mRNA
CTD
PMID:19376150
NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781
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Ankrd11
ankyrin repeat domain containing 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD11 mRNA
CTD
PMID:19376150
NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
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Ankrd13d
ankyrin repeat domain 13D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD13D mRNA
CTD
PMID:19376150
NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933
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Ap1g2
adaptor related protein complex 1 subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP1G2 mRNA
CTD
PMID:19376150
NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004
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Ap3s2
adaptor related protein complex 3 subunit sigma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP3S2 mRNA
CTD
PMID:19376150
NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322
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Apeh
acylaminoacyl-peptide hydrolase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of APEH mRNA
CTD
PMID:19376150
NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
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Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
multiple interactions increases expression increases activity
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein] Hypochlorous Acid results in increased activity of APEX1 protein
CTD
PMID:12231548
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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Api5
apoptosis inhibitor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of API5 mRNA
CTD
PMID:19376150
NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264
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Apoa1
apolipoprotein A1
multiple interactions
ISO
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein; Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]
CTD
PMID:33861588
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Appbp2
amyloid beta precursor protein binding protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of APPBP2 mRNA
CTD
PMID:19376150
NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
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Arcn1
archain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARCN1 mRNA
CTD
PMID:19376150
NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
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Arhgap24
Rho GTPase activating protein 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGAP24 mRNA
CTD
PMID:19376150
NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
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Arhgef1
Rho guanine nucleotide exchange factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGEF1 mRNA
CTD
PMID:19376150
NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
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Arih1
ariadne RBR E3 ubiquitin protein ligase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARIH1 mRNA
CTD
PMID:19376150
NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
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Arl2
ARF like GTPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARL2 mRNA
CTD
PMID:19376150
NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119
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Atxn3
ataxin 3
increases expression
ISO
Hypochlorous Acid results in increased expression of ATXN3 mRNA
CTD
PMID:19376150
NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
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B3gat3
beta-1,3-glucuronyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of B3GAT3 mRNA
CTD
PMID:19376150
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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Bace1
beta-secretase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BACE1 mRNA
CTD
PMID:19376150
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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Bckdk
branched chain ketoacid dehydrogenase kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BCKDK mRNA
CTD
PMID:19376150
NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
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Bclaf1
BCL2-associated transcription factor 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BCLAF1 mRNA
CTD
PMID:19376150
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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Bhlhe40
basic helix-loop-helix family, member e40
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BHLHE40 mRNA
CTD
PMID:19376150
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Blvrb
biliverdin reductase B
increases expression
ISO
Hypochlorous Acid results in increased expression of BLVRB mRNA
CTD
PMID:19376150
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Brd4
bromodomain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD4 mRNA
CTD
PMID:19376150
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
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Brd8
bromodomain containing 8
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD8 mRNA
CTD
PMID:19376150
NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884
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Bri3
brain protein I3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRI3 mRNA
CTD
PMID:19376150
NCBI chr12:10,341,007...10,364,655
Ensembl chr12:10,341,011...10,364,735
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Brms1
BRMS1, transcriptional repressor and anoikis regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRMS1 mRNA
CTD
PMID:19376150
NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
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Btbd2
BTB domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BTBD2 mRNA
CTD
PMID:19376150
NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344
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Bzw1
basic leucine zipper and W2 domains 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BZW1 mRNA
CTD
PMID:19376150
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
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Cab39
calcium binding protein 39
increases expression
ISO
Hypochlorous Acid results in increased expression of CAB39 mRNA
CTD
PMID:19376150
NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
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Camk1d
calcium/calmodulin-dependent protein kinase ID
increases expression
ISO
Hypochlorous Acid results in increased expression of CAMK1D mRNA
CTD
PMID:19376150
NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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Canx
calnexin
increases expression
ISO
Hypochlorous Acid results in increased expression of CANX mRNA
CTD
PMID:19376150
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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Capn5
calpain 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAPN5 mRNA
CTD
PMID:19376150
NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
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Car12
carbonic anhydrase 12
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAR12 mRNA
CTD
PMID:19376150
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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Cat
catalase
multiple interactions increases activity increases expression
ISO
CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased activity of CAT protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein] Hypochlorous Acid results in increased expression of CAT mRNA
CTD
PMID:17980396 PMID:19376150 PMID:36924976
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccnd3
cyclin D3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CCND3 mRNA
CTD
PMID:19376150
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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Cd47
Cd47 molecule
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CD47 mRNA
CTD
PMID:19376150
NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
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Cdc42
cell division cycle 42
increases expression
ISO
Hypochlorous Acid results in increased expression of CDC42 mRNA
CTD
PMID:19376150
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdca7l
cell division cycle associated 7 like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDCA7L mRNA
CTD
PMID:19376150
NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
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Cdk5rap3
CDK5 regulatory subunit associated protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK5RAP3 mRNA
CTD
PMID:19376150
NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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Cdk6
cyclin-dependent kinase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK6 mRNA
CTD
PMID:19376150
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdk7
cyclin-dependent kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of CDK7 mRNA
CTD
PMID:19376150
NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
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Cds1
CDP-diacylglycerol synthase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDS1 mRNA
CTD
PMID:19376150
NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
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Cds2
CDP-diacylglycerol synthase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of CDS2 mRNA
CTD
PMID:19376150
NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
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Cep43
centrosomal protein 43
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CEP43 mRNA
CTD
PMID:19376150
NCBI chr 1:52,533,418...52,564,025
Ensembl chr 1:52,533,428...52,563,923
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Cep76
centrosomal protein 76
increases expression
ISO
Hypochlorous Acid results in increased expression of CEP76 mRNA
CTD
PMID:19376150
NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504
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Cerk
ceramide kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CERK mRNA
CTD
PMID:19376150
NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759
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Chd3
chromodomain helicase DNA binding protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD3 mRNA
CTD
PMID:19376150
NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
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Chd4
chromodomain helicase DNA binding protein 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD4 mRNA
CTD
PMID:19376150
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
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Chit1
chitinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHIT1 mRNA
CTD
PMID:19376150
NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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Chordc1
cysteine and histidine rich domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CHORDC1 mRNA
CTD
PMID:19376150
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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Clec4d
C-type lectin domain family 4, member D
increases expression
ISO
Hypochlorous Acid results in increased expression of CLEC4D mRNA
CTD
PMID:19376150
NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848
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Cln6
CLN6, transmembrane ER protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLN6 mRNA
CTD
PMID:19376150
NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
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Clta
clathrin, light chain A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLTA mRNA
CTD
PMID:19376150
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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Coro1a
coronin 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CORO1A mRNA
CTD
PMID:19376150
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
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Ctdsp1
CTD small phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTDSP1 mRNA
CTD
PMID:19376150
NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297
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Ctnnbip1
catenin, beta-interacting protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNNBIP1 mRNA
CTD
PMID:19376150
NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
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Ctns
cystinosin, lysosomal cystine transporter
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNS mRNA
CTD
PMID:19376150
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Ctsb
cathepsin B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTSB mRNA
CTD
PMID:19376150
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Cul5
cullin 5
increases expression
ISO
Hypochlorous Acid results in increased expression of CUL5 mRNA
CTD
PMID:19376150
NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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Cyp20a1
cytochrome P450, family 20, subfamily a, polypeptide 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CYP20A1 mRNA
CTD
PMID:19376150
NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123
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Dab2
DAB adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DAB2 mRNA
CTD
PMID:19376150
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Hypochlorous Acid results in increased expression of DDIT3 mRNA
CTD
PMID:19376150
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx10
DEAD-box helicase 10
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX10 mRNA
CTD
PMID:19376150
NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
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Ddx3x
DEAD-box helicase 3, X-linked
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX3X mRNA
CTD
PMID:19376150
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
G
Dennd1a
DENN domain containing 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DENND1A mRNA
CTD
PMID:19376150
NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062
G
Dhx33
DEAH-box helicase 33
increases expression
ISO
Hypochlorous Acid results in increased expression of DHX33 mRNA
CTD
PMID:19376150
NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567
G
Dlst
dihydrolipoamide S-succinyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DLST mRNA
CTD
PMID:19376150
NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
G
Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNAJA2 mRNA
CTD
PMID:19376150
NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
G
Dnmt1
DNA methyltransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DNMT1 mRNA
CTD
PMID:19376150
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
G
Dnmt3l
DNA methyltransferase 3 like
increases expression
ISO
Hypochlorous Acid results in increased expression of DNMT3L mRNA
CTD
PMID:19376150
NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
G
Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNTTIP2 mRNA
CTD
PMID:19376150
NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581
G
Dr1
down-regulator of transcription 1
increases expression
ISO
Hypochlorous Acid results in increased expression of DR1 mRNA
CTD
PMID:19376150
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
G
Dtnb
dystrobrevin, beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTNB mRNA
CTD
PMID:19376150
NCBI chr 6:26,566,418...26,763,467
Ensembl chr 6:26,566,925...26,766,335
G
Dtwd2
DTW domain containing 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DTWD2 mRNA
CTD
PMID:19376150
NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832
G
Dtx3
deltex E3 ubiquitin ligase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTX3 mRNA
CTD
PMID:19376150
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
G
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EEFSEC mRNA
CTD
PMID:19376150
NCBI chr 4:120,719,616...120,915,779
Ensembl chr 4:120,707,133...120,915,779
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein
CTD
PMID:18156441
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ehmt2
euchromatic histone lysine methyltransferase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EHMT2 mRNA
CTD
PMID:19376150
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
G
Eif5
eukaryotic translation initiation factor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of EIF5 mRNA
CTD
PMID:19376150
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
G
Eloa
elongin A
increases expression
ISO
Hypochlorous Acid results in increased expression of ELOA mRNA
CTD
PMID:19376150
NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765
G
Eri3
ERI1 exoribonuclease family member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERI3 mRNA
CTD
PMID:19376150
NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:131,016,126...131,143,329
G
Erp29
endoplasmic reticulum protein 29
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERP29 mRNA
CTD
PMID:19376150
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
G
Esco1
establishment of sister chromatid cohesion N-acetyltransferase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ESCO1 mRNA
CTD
PMID:19376150
NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942
G
Esd
esterase D
increases expression
ISO
Hypochlorous Acid results in increased expression of ESD mRNA
CTD
PMID:19376150
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
G
Exosc5
exosome component 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EXOSC5 mRNA
CTD
PMID:19376150
NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
G
Fance
FA complementation group E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FANCE mRNA
CTD
PMID:19376150
NCBI chr20:6,369,416...6,386,631
Ensembl chr20:6,375,573...6,386,631
G
Fastk
Fas-activated serine/threonine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FASTK mRNA
CTD
PMID:19376150
NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430
G
Fbxl3
F-box and leucine-rich repeat protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of FBXL3 mRNA
CTD
PMID:19376150
NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867
G
Fbxw5
F-box and WD repeat domain containing 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW5 mRNA
CTD
PMID:19376150
NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092
G
Fbxw7
F-box and WD repeat domain containing 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW7 mRNA
CTD
PMID:19376150
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FGR mRNA
CTD
PMID:19376150
NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
G
Fktn
fukutin
increases expression
ISO
Hypochlorous Acid results in increased expression of FKTN mRNA
CTD
PMID:19376150
NCBI chr 5:68,339,803...68,396,412
Ensembl chr 5:68,340,028...68,396,409
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of FOS mRNA; Hypochlorous Acid results in increased expression of FOS protein
CTD
PMID:19376150
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxred1
FAD-dependent oxidoreductase domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FOXRED1 mRNA
CTD
PMID:19376150
NCBI chr 8:33,551,010...33,560,227
Ensembl chr 8:33,551,013...33,560,192
G
Ftl1
ferritin light chain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of FTL1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions decreases activity
ISO
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]
CTD
PMID:36924976
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45A mRNA
CTD
PMID:19376150
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45B mRNA
CTD
PMID:19376150
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45G mRNA
CTD
PMID:19376150
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
G
Galk1
galactokinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GALK1 mRNA
CTD
PMID:19376150
NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
G
Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions affects expression increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA] Hypochlorous Acid affects the expression of GCLC mRNA
CTD
PMID:17980396 PMID:18648578
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of GCLM mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gmfb
glia maturation factor, beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GMFB mRNA
CTD
PMID:19376150
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
G
Gnai3
G protein subunit alpha i3
increases expression
ISO
Hypochlorous Acid results in increased expression of GNAI3 mRNA
CTD
PMID:19376150
NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
G
Gnb2
G protein subunit beta 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GNB2 mRNA
CTD
PMID:19376150
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
G
Gopc
golgi associated PDZ and coiled-coil motif containing
increases expression
ISO
Hypochlorous Acid results in increased expression of GOPC mRNA
CTD
PMID:19376150
NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903
G
Gpbp1
GC-rich promoter binding protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of GPBP1 mRNA
CTD
PMID:19376150
NCBI chr 2:43,023,504...43,091,146
Ensembl chr 2:43,023,504...43,090,907
G
Gpx1
glutathione peroxidase 1
decreases expression increases activity multiple interactions
ISO
Hypochlorous Acid results in decreased expression of GPX1 mRNA Hypochlorous Acid results in increased activity of GPX1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx4
glutathione peroxidase 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GPX4 mRNA
CTD
PMID:19376150
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grn
granulin precursor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GRN mRNA
CTD
PMID:19376150
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
G
Gsr
glutathione-disulfide reductase
increases expression multiple interactions decreases activity
ISO
Hypochlorous Acid results in increased expression of GSR mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein]
CTD
PMID:17980396 PMID:36924976
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
ISO
Hypochlorous Acid results in increased expression of GSS mRNA
CTD
PMID:17980396
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
H2bc18
H2B clustered histone 18
increases expression
ISO
Hypochlorous Acid results in increased expression of H2BC18 mRNA
CTD
PMID:19376150
NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529
G
Haghl
hydroxyacylglutathione hydrolase-like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAGHL mRNA
CTD
PMID:19376150
NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665
G
Haus4
HAUS augmin-like complex, subunit 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAUS4 mRNA
CTD
PMID:19376150
NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938
G
Hdac10
histone deacetylase 10
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC10 mRNA
CTD
PMID:19376150
NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
G
Hdac5
histone deacetylase 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC5 mRNA
CTD
PMID:19376150
NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
G
Hdac6
histone deacetylase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC6 mRNA
CTD
PMID:19376150
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
G
Hexd
hexosaminidase D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HEXD mRNA
CTD
PMID:19376150
NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799
G
Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK2 mRNA
CTD
PMID:19376150
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hipk3
homeodomain interacting protein kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK3 mRNA
CTD
PMID:19376150
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
G
Hk1
hexokinase 1
multiple interactions decreases activity
ISO
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein]
CTD
PMID:36924976
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
G
Hmga2
high mobility group AT-hook 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HMGA2 mRNA
CTD
PMID:19376150
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA] [Quercetin co-treated with Hypochlorous Acid] results in increased expression of HMOX1 protein Hypochlorous Acid results in increased expression of HMOX1 mRNA; Hypochlorous Acid results in increased expression of HMOX1 protein
CTD
PMID:17980396 PMID:18156441 PMID:19376150 PMID:24017971
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hpcal1
hippocalcin-like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPCAL1 mRNA
CTD
PMID:19376150
NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
increases mutagenesis
ISO
Hypochlorous Acid results in increased mutagenesis of HPRT1 gene
CTD
PMID:19892774
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPS1 mRNA
CTD
PMID:19376150
NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of HSP90AA1 mRNA
CTD
PMID:19376150
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa13
heat shock protein family A (Hsp70) member 13
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA13 mRNA
CTD
PMID:19376150
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]
CTD
PMID:12231548
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA1B mRNA
CTD
PMID:19376150
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
G
Ifng
interferon gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IFNG mRNA
CTD
PMID:19376150
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IKBKG mRNA
CTD
PMID:19376150
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
G
Il10
interleukin 10
increases expression
ISO
Hypochlorous Acid results in increased expression of IL10 mRNA
CTD
PMID:19376150
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il1b
interleukin 1 beta
increases expression
ISO
Hypochlorous Acid results in increased expression of IL1B mRNA
CTD
PMID:19376150
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of IL6 mRNA
CTD
PMID:19376150
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ing2
inhibitor of growth family, member 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ING2 mRNA
CTD
PMID:19376150
NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
G
Ints7
integrator complex subunit 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of INTS7 mRNA
CTD
PMID:19376150
NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592
G
Ints8
integrator complex subunit 8
increases expression
ISO
Hypochlorous Acid results in increased expression of INTS8 mRNA
CTD
PMID:19376150
NCBI chr 5:24,295,542...24,344,642
Ensembl chr 5:24,297,191...24,344,740
G
Itgb5
integrin subunit beta 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ITGB5 mRNA
CTD
PMID:19376150
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
G
Jag1
jagged canonical Notch ligand 1
increases expression
ISO
Hypochlorous Acid results in increased expression of JAG1 mRNA
CTD
PMID:19376150
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
G
Jak3
Janus kinase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of JAK3 mRNA
CTD
PMID:19376150
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
G
Kbtbd8
kelch repeat and BTB domain containing 8
increases expression
ISO
Hypochlorous Acid results in increased expression of KBTBD8 mRNA
CTD
PMID:19376150
NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
G
Keap1
Kelch-like ECH-associated protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KEAP1 mRNA
CTD
PMID:17980396
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Kif1b
kinesin family member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF1B mRNA
CTD
PMID:19376150
NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
G
Kif24
kinesin family member 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of KIF24 mRNA
CTD
PMID:19376150
NCBI chr 5:56,561,019...56,628,040
Ensembl chr 5:56,561,154...56,628,025
G
Kif3c
kinesin family member 3C
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF3C mRNA
CTD
PMID:19376150
NCBI chr 6:26,367,092...26,406,033
Ensembl chr 6:26,366,531...26,406,130
G
Kif5b
kinesin family member 5B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF5B mRNA
CTD
PMID:19376150
NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
G
Kpna1
karyopherin subunit alpha 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA1 mRNA
CTD
PMID:19376150
NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623
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Kpna4
karyopherin subunit alpha 4
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA4 mRNA
CTD
PMID:19376150
NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
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Krr1
KRR1, small subunit processome component homolog
increases expression
ISO
Hypochlorous Acid results in increased expression of KRR1 mRNA
CTD
PMID:19376150
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
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Lcat
lecithin cholesterol acyltransferase
multiple interactions
ISO
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein
CTD
PMID:33861588
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Ldha
lactate dehydrogenase A
increases activity multiple interactions
ISO
Hypochlorous Acid results in increased activity of LDHA protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]
CTD
PMID:36924976
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Limd2
LIM domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LIMD2 mRNA
CTD
PMID:19376150
NCBI chr10:91,090,279...91,092,772
Ensembl chr10:91,090,280...91,092,775
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Lmf1
lipase maturation factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LMF1 mRNA
CTD
PMID:19376150
NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
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Loxl3
lysyl oxidase-like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LOXL3 mRNA
CTD
PMID:19376150
NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
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Lrp1
LDL receptor related protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LRP1 mRNA
CTD
PMID:19376150
NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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Lrrc8d
leucine rich repeat containing 8 VRAC subunit D
increases expression
ISO
Hypochlorous Acid results in increased expression of LRRC8D mRNA
CTD
PMID:19376150
NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877
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Maff
MAF bZIP transcription factor F
increases expression
ISO
Hypochlorous Acid results in increased expression of MAFF mRNA
CTD
PMID:18156441
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
Hypochlorous Acid results in increased expression of MAFG mRNA
CTD
PMID:18156441
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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Man1a2
mannosidase, alpha, class 1A, member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of MAN1A2 mRNA
CTD
PMID:19376150
NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332
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Man1c1
mannosidase, alpha, class 1C, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN1C1 mRNA
CTD
PMID:19376150
NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421
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Man2c1
mannosidase, alpha, class 2C, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN2C1 mRNA
CTD
PMID:19376150
NCBI chr 8:57,537,879...57,549,691
Ensembl chr 8:57,537,321...57,549,690
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Map3k7
mitogen activated protein kinase kinase kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of MAP3K7 mRNA
CTD
PMID:19376150
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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Map4k1
mitogen activated protein kinase kinase kinase kinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAP4K1 mRNA
CTD
PMID:19376150
NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD
PMID:18156441
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk10
mitogen activated protein kinase 10
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK10 protein
CTD
PMID:18156441
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD
PMID:18156441
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk6
mitogen-activated protein kinase 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MAPK6 mRNA
CTD
PMID:19376150
NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD
PMID:18156441
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK9 protein
CTD
PMID:18156441
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Marchf2
membrane associated ring-CH-type finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MARCHF2 mRNA
CTD
PMID:19376150
NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794
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Me1
malic enzyme 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ME1 mRNA
CTD
PMID:19376150
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Mfap1a
microfibrillar-associated protein 1A
increases expression
ISO
Hypochlorous Acid results in increased expression of MFAP1 mRNA
CTD
PMID:19376150
NCBI chr 3:108,440,163...108,456,744
Ensembl chr 3:108,438,845...108,456,750
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Mfsd13a
major facilitator superfamily domain containing 13A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MFSD13A mRNA
CTD
PMID:19376150
NCBI chr 1:245,216,610...245,236,314
Ensembl chr 1:245,217,067...245,236,767
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Miip
migration and invasion inhibitory protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MIIP mRNA
CTD
PMID:19376150
NCBI chr 5:158,292,510...158,299,533
Ensembl chr 5:158,292,511...158,299,694
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Mob1a
MOB kinase activator 1A
increases expression
ISO
Hypochlorous Acid results in increased expression of MOB1A mRNA
CTD
PMID:19376150
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561 Ensembl chr 1:115,831,551...115,848,561
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Mpo
myeloperoxidase
multiple interactions increases abundance increases chemical synthesis
ISO
4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; MitoTEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; TEMPOL-H inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]
CTD
PMID:7772042 PMID:20939553 PMID:34085520 PMID:35575633
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mrpl4
mitochondrial ribosomal protein L4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MRPL4 mRNA
CTD
PMID:19376150
NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
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Msrb1
methionine sulfoxide reductase B1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MSRB1 mRNA
CTD
PMID:19376150
NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
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Mta1
metastasis associated 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA1 mRNA
CTD
PMID:19376150
NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
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Mta3
metastasis associated 1 family, member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA3 mRNA
CTD
PMID:19376150
NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883
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Mtarc2
mitochondrial amidoxime reducing component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTARC2 mRNA
CTD
PMID:19376150
NCBI chr13:96,362,810...96,397,284
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Mtdh
metadherin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTDH mRNA
CTD
PMID:19376150
NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
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Mtmr6
myotubularin related protein 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MTMR6 mRNA
CTD
PMID:19376150
NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
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Mtpn
myotrophin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTPN mRNA
CTD
PMID:19376150
NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
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Muc16
mucin 16, cell surface associated
increases expression
ISO
Hypochlorous Acid results in increased expression of MUC16 mRNA
CTD
PMID:19376150
NCBI chr 8:16,164,531...16,323,126
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MVD mRNA
CTD
PMID:19376150
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Myh9
myosin, heavy chain 9
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYH9 mRNA
CTD
PMID:19376150
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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Myo1f
myosin IF
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO1F mRNA
CTD
PMID:19376150
NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911
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Myo9b
myosin IXb
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO9B mRNA
CTD
PMID:19376150
NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126
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Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of NAA15 mRNA
CTD
PMID:19376150
NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756
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Ncaph2
non-SMC condensin II complex, subunit H2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NCAPH2 mRNA
CTD
PMID:19376150
NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938
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Ndufs2
NADH:ubiquinone oxidoreductase core subunit S2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS2 mRNA
CTD
PMID:19376150
NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS7 mRNA
CTD
PMID:19376150
NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
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Nelfe
negative elongation factor complex member E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELFE mRNA
CTD
PMID:19376150
NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
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Nell1
neural EGFL like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELL1 mRNA
CTD
PMID:19376150
NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions increases expression affects response to substance
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased expression of NFE2L2 protein Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] NFE2L2 protein affects the susceptibility to Hypochlorous Acid
CTD
PMID:17980396 PMID:18156441
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nol11
nucleolar protein 11
increases expression
ISO
Hypochlorous Acid results in increased expression of NOL11 mRNA
CTD
PMID:19376150
NCBI chr10:92,119,000...92,141,688
Ensembl chr10:92,121,833...92,141,677
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression affects expression
ISO
Hypochlorous Acid results in increased expression of NQO1 mRNA Hypochlorous Acid affects the expression of NQO1 mRNA
CTD
PMID:17980396 PMID:18156441 PMID:18648578 PMID:19376150
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NR1D1 mRNA
CTD
PMID:19376150
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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Nrp1
neuropilin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of NRP1 mRNA
CTD
PMID:19376150
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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Nup54
nucleoporin 54
increases expression
ISO
Hypochlorous Acid results in increased expression of NUP54 mRNA
CTD
PMID:19376150
NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
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Otud4
OTU deubiquitinase 4
increases expression
ISO
Hypochlorous Acid results in increased expression of OTUD4 mRNA
CTD
PMID:19376150
NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815
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P3h3
prolyl 3-hydroxylase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of P3H3 mRNA
CTD
PMID:19376150
NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035
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Pacsin3
protein kinase C and casein kinase substrate in neurons 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PACSIN3 mRNA
CTD
PMID:19376150
NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811
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Pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PAFAH1B2 mRNA
CTD
PMID:19376150
NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:46,261,064...46,279,833
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Pak1ip1
PAK1 interacting protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PAK1IP1 mRNA
CTD
PMID:19376150
NCBI chr17:23,742,217...23,753,325
Ensembl chr17:23,741,414...23,753,324
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Papola
poly (A) polymerase alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PAPOLA mRNA
CTD
PMID:19376150
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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Parvb
parvin, beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PARVB mRNA
CTD
PMID:19376150
NCBI chr 7:115,360,254...115,445,767
Ensembl chr 7:115,360,261...115,445,766
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Pcdhgc3
protocadherin gamma subfamily C, 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PCDHGC3 mRNA
CTD
PMID:19376150
NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
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Pcgf2
polycomb group ring finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PCGF2 mRNA
CTD
PMID:19376150
NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
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Pex6
peroxisomal biogenesis factor 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PEX6 mRNA
CTD
PMID:19376150
NCBI chr 9:14,258,145...14,270,335
Ensembl chr 9:14,258,145...14,270,303
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Pgrmc2
progesterone receptor membrane component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PGRMC2 mRNA
CTD
PMID:19376150
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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Phka2
phosphorylase kinase regulatory subunit alpha 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKA2 mRNA
CTD
PMID:19376150
NCBI chr X:34,170,959...34,293,498
Ensembl chr X:34,171,323...34,293,466
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Phkg2
phosphorylase kinase catalytic subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKG2 mRNA
CTD
PMID:19376150
NCBI chr 1:182,184,362...182,197,124
Ensembl chr 1:182,184,650...182,197,124
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Phpt1
phosphohistidine phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHPT1 mRNA
CTD
PMID:19376150
NCBI chr 3:8,392,926...8,394,325
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Pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PIK3C2A mRNA
CTD
PMID:19376150
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PKMYT1 mRNA
CTD
PMID:19376150
NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
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Plcb3
phospholipase C beta 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLCB3 mRNA
CTD
PMID:19376150
NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
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Plxnb2
plexin B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLXNB2 mRNA
CTD
PMID:19376150
NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330
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Pnkd
PNKD metallo-beta-lactamase domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PNKD mRNA
CTD
PMID:19376150
NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
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Pold1
DNA polymerase delta 1, catalytic subunit
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLD1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
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Poll
DNA polymerase lambda
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLL mRNA
CTD
PMID:19376150
NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
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Pon1
paraoxonase 1
decreases activity increases oxidation multiple interactions
ISO
Hypochlorous Acid results in decreased activity of PON1 protein Hypochlorous Acid results in increased oxidation of PON1 protein Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]
CTD
PMID:14671042 PMID:15104111
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Ppfia4
PTPRF interacting protein alpha 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPFIA4 mRNA
CTD
PMID:19376150
NCBI chr13:45,753,827...45,802,305
Ensembl chr13:45,753,827...45,802,261
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Ppox
protoporphyrinogen oxidase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPOX mRNA
CTD
PMID:19376150
NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
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Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPP2R1A mRNA
CTD
PMID:19376150
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
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Prdx1
peroxiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PRDX1 mRNA
CTD
PMID:19376150
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx5
peroxiredoxin 5
decreases activity multiple interactions
ISO
Hypochlorous Acid results in decreased activity of PRDX5 protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of PRDX5 protein]
CTD
PMID:36924976
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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Prkar2b
protein kinase cAMP-dependent type II regulatory subunit beta
increases expression
ISO
Hypochlorous Acid results in increased expression of PRKAR2B mRNA
CTD
PMID:19376150
NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
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Procr
protein C receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PROCR mRNA
CTD
PMID:19376150
NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
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Psma7
proteasome 20S subunit alpha 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMA7 mRNA
CTD
PMID:19376150
NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
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Psmb3
proteasome 20S subunit beta 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMB3 mRNA
CTD
PMID:19376150
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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Psmc1
proteasome 26S subunit, ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC1 mRNA
CTD
PMID:19376150
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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Psmc2
proteasome 26S subunit, ATPase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC2 mRNA
CTD
PMID:19376150
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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Psmd1
proteasome 26S subunit, non-ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD1 mRNA
CTD
PMID:19376150
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd11
proteasome 26S subunit, non-ATPase 11
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD11 mRNA
CTD
PMID:19376150
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
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Psmd5
proteasome 26S subunit, non-ATPase 5
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD5 mRNA
CTD
PMID:19376150
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
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Psmd7
proteasome 26S subunit, non-ATPase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD7 mRNA
CTD
PMID:19376150
NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588
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Ptbp3
polypyrimidine tract binding protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTBP3 mRNA
CTD
PMID:19376150
NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
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Ptges2
prostaglandin E synthase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTGES2 mRNA
CTD
PMID:19376150
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
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Ptges3
prostaglandin E synthase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGES3 mRNA
CTD
PMID:19376150
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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Ptgir
prostaglandin I2 receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGIR mRNA
CTD
PMID:19376150
NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
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Ptov1
PTOV1, extended AT-hook containing adaptor protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTOV1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
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Ptp4a3
protein tyrosine phosphatase 4A3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTP4A3 mRNA
CTD
PMID:19376150
NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919
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Ptpn12
protein tyrosine phosphatase, non-receptor type 12
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN12 mRNA
CTD
PMID:19376150
NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
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Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN14 mRNA
CTD
PMID:19376150
NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
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Pwwp2b
PWWP domain containing 2B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PWWP2B mRNA
CTD
PMID:19376150
NCBI chr 1:194,040,395...194,059,979
Ensembl chr 1:194,041,341...194,059,958
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Rab10
RAB10, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB10 mRNA
CTD
PMID:19376150
NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193
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Rab18
RAB18, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB18 mRNA
CTD
PMID:19376150
NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
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Rab22a
RAB22A, member RAS oncogene family
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RAB22A mRNA
CTD
PMID:19376150
NCBI chr 3:162,459,727...162,506,129
Ensembl chr 3:162,459,726...162,506,137
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Rabep1
rabaptin, RAB GTPase binding effector protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RABEP1 mRNA
CTD
PMID:19376150
NCBI chr10:55,566,156...55,667,595
Ensembl chr10:55,566,185...55,665,973
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Ralgdsl1
ral guanine nucleotide dissociation stimulator like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL1 mRNA
CTD
PMID:19376150
NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191
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Ralgdsl2
ral guanine nucleotide dissociation stimulator like 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL2 mRNA
CTD
PMID:19376150
NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
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Rassf4
Ras association domain family member 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RASSF4 mRNA
CTD
PMID:19376150
NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
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Rbck1
RANBP2-type and C3HC4-type zinc finger containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RBCK1 mRNA
CTD
PMID:19376150
NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
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Rbm18
RNA binding motif protein 18
increases expression
ISO
Hypochlorous Acid results in increased expression of RBM18 mRNA
CTD
PMID:19376150
NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178
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Rbx1
ring-box 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RBX1 mRNA
CTD
PMID:19376150
NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Rdx
radixin
increases expression
ISO
Hypochlorous Acid results in increased expression of RDX mRNA
CTD
PMID:19376150
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
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Reep6
receptor accessory protein 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of REEP6 mRNA
CTD
PMID:19376150
NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
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Ric8a
RIC8 guanine nucleotide exchange factor A
increases expression
ISO
Hypochlorous Acid results in increased expression of RIC8A mRNA
CTD
PMID:19376150
NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467
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Riok3
RIO kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of RIOK3 mRNA
CTD
PMID:19376150
NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
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Rnaseh1
ribonuclease H1
increases expression
ISO
Hypochlorous Acid results in increased expression of RNASEH1 mRNA
CTD
PMID:19376150
NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
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Rnf115
ring finger protein 115
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF115 mRNA
CTD
PMID:19376150
NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823
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Rnf128
ring finger protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF128 mRNA
CTD
PMID:19376150
NCBI chr X:103,183,643...103,298,431
Ensembl chr X:103,183,831...103,298,423
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Rnf157
ring finger protein 157
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF157 mRNA
CTD
PMID:19376150
NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942
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Rnf183
ring finger protein 183
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF183 mRNA
CTD
PMID:19376150
NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
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Rnf26
ring finger protein 26
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF26 mRNA
CTD
PMID:19376150
NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331
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Rnf4
ring finger protein 4
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF4 mRNA
CTD
PMID:19376150
NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
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Rock1
Rho-associated coiled-coil containing protein kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ROCK1 mRNA
CTD
PMID:19376150
NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
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Rpf1
ribosome production factor 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BXDC5 mRNA
CTD
PMID:19376150
NCBI chr 2:235,403,020...235,417,546
Ensembl chr 2:235,403,021...235,417,807
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Rpl35
ribosomal protein L35
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPL35 mRNA
CTD
PMID:19376150
NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243
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Rps6kb2
ribosomal protein S6 kinase B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPS6KB2 mRNA
CTD
PMID:19376150
NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
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Rsl1d1
ribosomal L1 domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RSL1D1 mRNA
CTD
PMID:19376150
NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
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Ruvbl2
RuvB-like AAA ATPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RUVBL2 mRNA
CTD
PMID:19376150
NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
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Rwdd2a
RWD domain containing 2A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RWDD2A mRNA
CTD
PMID:19376150
NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300
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Satb2
SATB homeobox 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SATB2 mRNA
CTD
PMID:19376150
NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
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Sbf1
SET binding factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SBF1 mRNA
CTD
PMID:19376150
NCBI chr 7:120,358,338...120,385,022
Ensembl chr 7:120,358,338...120,384,902
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Scand1
SCAN domain-containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SCAND1 mRNA
CTD
PMID:19376150
NCBI chr 3:144,818,615...144,819,479
Ensembl chr 3:144,818,611...144,820,025
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Sdc3
syndecan 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SDC3 mRNA
CTD
PMID:19376150
NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480
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Sec63
SEC63 homolog, protein translocation regulator
increases expression
ISO
Hypochlorous Acid results in increased expression of SEC63 mRNA
CTD
PMID:19376150
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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Selplg
selectin P ligand
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SELPLG mRNA
CTD
PMID:19376150
NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
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Sema5a
semaphorin 5A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SEMA5A mRNA
CTD
PMID:19376150
NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
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Sergef
secretion regulating guanine nucleotide exchange factor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SERGEF mRNA
CTD
PMID:19376150
NCBI chr 1:96,949,660...97,152,529
Ensembl chr 1:96,949,661...97,152,496
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Serinc1
serine incorporator 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERINC1 mRNA
CTD
PMID:19376150
NCBI chr20:36,850,062...36,868,999
Ensembl chr20:36,850,076...36,896,691
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Serpinb9
serpin family B member 9
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINB9 mRNA
CTD
PMID:19376150
NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
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Serpine1
serpin family E member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINE1 mRNA
CTD
PMID:19376150
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Setd6
SET domain containing 6, protein lysine methyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SETD6 mRNA
CTD
PMID:19376150
NCBI chr19:9,343,309...9,350,477
Ensembl chr19:9,347,458...9,350,453
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Sh2b2
SH2B adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH2B2 mRNA
CTD
PMID:19376150
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
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Sh3bp1
SH3-domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH3BP1 mRNA
CTD
PMID:19376150
NCBI chr 7:110,457,626...110,470,201
Ensembl chr 7:110,457,710...110,470,201
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Sigirr
single Ig and TIR domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIGIRR mRNA
CTD
PMID:19376150
NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269
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Sipa1l1
signal-induced proliferation-associated 1 like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIPA1L1 mRNA
CTD
PMID:19376150
NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
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Sla
src-like adaptor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLA mRNA
CTD
PMID:19376150
NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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Slc20a1
solute carrier family 20 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC20A1 mRNA
CTD
PMID:19376150
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
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Slc23a2
solute carrier family 23 member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC23A2 mRNA
CTD
PMID:19376150
NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc25a1
solute carrier family 25 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A1 mRNA
CTD
PMID:19376150
NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
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Slc25a12
solute carrier family 25 member 12
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC25A12 mRNA
CTD
PMID:19376150
NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100
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Slc25a28
solute carrier family 25 member 28
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A28 mRNA
CTD
PMID:19376150
NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115
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Slc25a39
solute carrier family 25, member 39
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A39 mRNA
CTD
PMID:19376150
NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260
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Slc35b2
solute carrier family 35 member B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35B2 mRNA
CTD
PMID:19376150
NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
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Slc35c2
solute carrier family 35 member C2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35C2 mRNA
CTD
PMID:19376150
NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488
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Slc39a6
solute carrier family 39 member 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC39A6 mRNA
CTD
PMID:19376150
NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
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Slc40a1
solute carrier family 40 member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC40A1 mRNA
CTD
PMID:19376150
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC7A11 mRNA
CTD
PMID:19376150
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slk
STE20-like kinase
increases expression
ISO
Hypochlorous Acid results in increased expression of SLK mRNA
CTD
PMID:19376150
NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
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Slmap
sarcolemma associated protein
increases expression
ISO
Hypochlorous Acid results in increased expression of SLMAP mRNA
CTD
PMID:19376150
NCBI chr16:1,667,205...1,785,200
Ensembl chr16:1,667,208...1,785,149
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Smarca5
SNF2 related chromatin remodeling ATPase 5
increases expression
ISO
Hypochlorous Acid results in increased expression of SMARCA5 mRNA
CTD
PMID:19376150
NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
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Smarcd2
SWI/SNF related BAF chromatin remodeling complex subunit D2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMARCD2 mRNA
CTD
PMID:19376150
NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341
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Smyd1
SET and MYND domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMYD1 mRNA
CTD
PMID:19376150
NCBI chr 4:103,195,330...103,252,989
Ensembl chr 4:103,200,322...103,311,766
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Smyd4
SET and MYND domain containing 4
increases expression
ISO
Hypochlorous Acid results in increased expression of SMYD4 mRNA
CTD
PMID:19376150
NCBI chr10:60,200,067...60,246,387
Ensembl chr10:60,200,114...60,246,387
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Snrpa
small nuclear ribonucleoprotein polypeptide A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNRPA mRNA
CTD
PMID:19376150
NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
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Snx17
sorting nexin 17
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNX17 mRNA
CTD
PMID:19376150
NCBI chr 6:25,177,528...25,183,001
Ensembl chr 6:25,177,391...25,183,030
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Snx6
sorting nexin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SNX6 mRNA
CTD
PMID:19376150
NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
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Sod1
superoxide dismutase 1
increases expression multiple interactions increases activity
ISO
Hypochlorous Acid results in increased expression of SOD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of SOD1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sqstm1
sequestosome 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SQSTM1 mRNA
CTD
PMID:19376150
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srxn1
sulfiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SRXN1 mRNA
CTD
PMID:19376150
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Ssb
small RNA binding exonuclease protection factor La
increases expression
ISO
Hypochlorous Acid results in increased expression of SSB mRNA
CTD
PMID:19376150
NCBI chr 3:54,616,616...54,626,203
Ensembl chr 3:54,616,619...54,626,203
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St14
ST14 transmembrane serine protease matriptase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST14 mRNA
CTD
PMID:19376150
NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST3GAL3 mRNA
CTD
PMID:19376150
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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Stxbp2
syntaxin binding protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of STXBP2 mRNA
CTD
PMID:19376150
NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
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Taok1
TAO kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TAOK1 mRNA
CTD
PMID:19376150
NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766
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Tbc1d23
TBC1 domain family, member 23
increases expression
ISO
Hypochlorous Acid results in increased expression of TBC1D23 mRNA
CTD
PMID:19376150
NCBI chr11:43,303,355...43,361,507
Ensembl chr11:43,303,355...43,361,503
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Tbcd
tubulin folding cofactor D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBCD mRNA
CTD
PMID:19376150
NCBI chr10:106,717,340...106,874,126
Ensembl chr10:106,717,367...106,874,122
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Tbcel
tubulin folding cofactor E-like
increases expression
ISO
Hypochlorous Acid results in increased expression of TBCEL mRNA
CTD
PMID:19376150
NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552
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Tbrg4
transforming growth factor beta regulator 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBRG4 mRNA
CTD
PMID:19376150
NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756
G
Tfrc
transferrin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of TFRC mRNA
CTD
PMID:19376150
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Tifa
TRAF-interacting protein with forkhead-associated domain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIFA mRNA
CTD
PMID:19376150
NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
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Timm44
translocase of inner mitochondrial membrane 44
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIMM44 mRNA
CTD
PMID:19376150
NCBI chr12:2,612,581...2,629,374
Ensembl chr12:2,612,581...2,629,351
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Tjp3
tight junction protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TJP3 mRNA
CTD
PMID:19376150
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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Tmed2
transmembrane p24 trafficking protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TMED2 mRNA
CTD
PMID:19376150
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Tmem128
transmembrane protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM128 mRNA
CTD
PMID:19376150
NCBI chr14:72,539,530...72,548,623
Ensembl chr14:72,539,532...72,548,550
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Tmem33
transmembrane protein 33
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM33 mRNA
CTD
PMID:19376150
NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715
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Tnrc6a
trinucleotide repeat containing adaptor 6A
increases expression
ISO
Hypochlorous Acid results in increased expression of TNRC6A mRNA
CTD
PMID:19376150
NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
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Topbp1
DNA topoisomerase II binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TOPBP1 mRNA
CTD
PMID:19376150
NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
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Tp53i11
tumor protein p53 inducible protein 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRP53I11 mRNA
CTD
PMID:19376150
NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
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Tpp2
tripeptidyl peptidase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TPP2 mRNA
CTD
PMID:19376150
NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
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Trap1
TNF receptor-associated protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRAP1 mRNA
CTD
PMID:19376150
NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
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Treml4
triggering receptor expressed on myeloid cells-like 4
increases expression
ISO
Hypochlorous Acid results in increased expression of TREML4 mRNA
CTD
PMID:19376150
NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253
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Trim27
tripartite motif-containing 27
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRIM27 mRNA
CTD
PMID:19376150
NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
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Trpt1
tRNA phosphotransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRPT1 mRNA
CTD
PMID:19376150
NCBI chr 1:204,186,295...204,191,294
Ensembl chr 1:204,186,295...204,191,294
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Ttc1
tetratricopeptide repeat domain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TTC1 mRNA
CTD
PMID:19376150
NCBI chr10:28,202,325...28,227,464
Ensembl chr10:28,202,325...28,227,472
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Ttll3
tubulin tyrosine ligase like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TTLL3 mRNA
CTD
PMID:19376150
NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
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Txndc9
thioredoxin domain containing 9
increases expression
ISO
Hypochlorous Acid results in increased expression of TXNDC9 mRNA
CTD
PMID:19376150
NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279 Ensembl chr 9:40,211,412...40,384,279
G
Txnrd1
thioredoxin reductase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TXNRD1 mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Ube2d3
ubiquitin-conjugating enzyme E2D 3
increases expression
ISO
Hypochlorous Acid results in increased expression of UBE2D3 mRNA
CTD
PMID:19376150
NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
G
Ugcg
UDP-glucose ceramide glucosyltransferase
increases expression
ISO
Hypochlorous Acid results in increased expression of UGCG mRNA
CTD
PMID:19376150
NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
G
Unc119
unc-119 lipid binding chaperone
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC119 mRNA
CTD
PMID:19376150
NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339
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Unc93b1
unc-93 homolog B1, TLR signaling regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC93B1 mRNA
CTD
PMID:19376150
NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338
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Uso1
USO1 vesicle transport factor
increases expression
ISO
Hypochlorous Acid results in increased expression of USO1 mRNA
CTD
PMID:19376150
NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171
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Usp12
ubiquitin specific peptidase 12
increases expression
ISO
Hypochlorous Acid results in increased expression of USP12 mRNA
CTD
PMID:19376150
NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656
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Usp15
ubiquitin specific peptidase 15
increases expression
ISO
Hypochlorous Acid results in increased expression of USP15 mRNA
CTD
PMID:19376150
NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
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Usp16
ubiquitin specific peptidase 16
increases expression
ISO
Hypochlorous Acid results in increased expression of USP16 mRNA
CTD
PMID:19376150
NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
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Usp2
ubiquitin specific peptidase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of USP2 mRNA
CTD
PMID:19376150
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Vamp2
vesicle-associated membrane protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VAMP2 mRNA
CTD
PMID:19376150
NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
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Vars2
valyl-tRNA synthetase 2, mitochondrial
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VARS2 mRNA
CTD
PMID:19376150
NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994
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Vmp1
vacuole membrane protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of VMP1 mRNA
CTD
PMID:19376150
NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
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Vps13d
vacuolar protein sorting 13 homolog D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS13D mRNA
CTD
PMID:19376150
NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
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Vps16
VPS16 core subunit of CORVET and HOPS complexes
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS16 mRNA
CTD
PMID:19376150
NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
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Vps35
VPS35 retromer complex component
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS35 mRNA
CTD
PMID:19376150
NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
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Vps54
VPS54 subunit of GARP complex
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS54 mRNA
CTD
PMID:19376150
NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857
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Wbp1
WW domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WBP1 mRNA
CTD
PMID:19376150
NCBI chr 4:115,625,168...115,627,567
Ensembl chr 4:115,625,168...115,627,624
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Wdr62
WD repeat domain 62
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WDR62 mRNA
CTD
PMID:19376150
NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
increases expression
ISO
Hypochlorous Acid results in increased expression of YWHAZ mRNA
CTD
PMID:19376150
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
G
Zbtb47
zinc finger and BTB domain containing 47
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZBTB47 mRNA
CTD
PMID:19376150
NCBI chr 8:121,420,758...121,434,365
Ensembl chr 8:121,423,696...121,433,225
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Zc3h15
zinc finger CCCH-type containing 15
increases expression
ISO
Hypochlorous Acid results in increased expression of ZC3H15 mRNA
CTD
PMID:19376150
NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333
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Zdhhc14
zinc finger DHHC-type palmitoyltransferase 14
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZDHHC14 mRNA
CTD
PMID:19376150
NCBI chr 1:46,069,127...46,340,806
Ensembl chr 1:46,069,127...46,330,488
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Zfp24
zinc finger protein 24
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP24 mRNA
CTD
PMID:19376150
NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799
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Zfp316
zinc finger protein 316
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP316 mRNA
CTD
PMID:19376150
NCBI chr12:11,294,445...11,313,841
Ensembl chr12:11,293,980...11,312,177
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Zfp414
zinc finger protein 414
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP414 mRNA
CTD
PMID:19376150
NCBI chr 7:14,420,232...14,422,939
Ensembl chr 7:14,420,165...14,438,166
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Zfp638
zinc finger protein 638
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP638 mRNA
CTD
PMID:19376150
NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845
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Zfp652
zinc finger protein 652
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP652 mRNA
CTD
PMID:19376150
NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674
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Zfpm1
zinc finger protein, multitype 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFPM1 mRNA
CTD
PMID:19376150
NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
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Zmym3
zinc finger MYM-type containing 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZMYM3 mRNA
CTD
PMID:19376150
NCBI chr X:66,528,585...66,544,234
Ensembl chr X:66,528,585...66,544,782
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Zwint
ZW10 interacting kinetochore protein
increases expression
ISO
Hypochlorous Acid results in increased expression of ZWINT mRNA
CTD
PMID:19376150
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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