CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: halogen oxoacid
Accession: CHEBI:33425
browse the term
Synonyms: related_synonym: halogen oxoacids
G
CA1
carbonic anhydrase 1
decreases activity
EXP
chloric acid results in decreased activity of CA1 protein
CTD
PMID:15664814
NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014
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CA2
carbonic anhydrase 2
decreases activity
EXP
chloric acid results in decreased activity of CA2 protein
CTD
PMID:15664814
NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
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CA4
carbonic anhydrase 4
decreases activity
EXP
chloric acid results in decreased activity of CA4 protein
CTD
PMID:15664814
NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899
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CA5A
carbonic anhydrase 5A
decreases activity
EXP
chloric acid results in decreased activity of CA5A protein
CTD
PMID:15664814
NCBI chr16:87,881,549...87,936,529
Ensembl chr16:87,881,546...87,936,580
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CA9
carbonic anhydrase 9
decreases activity
EXP
chloric acid results in decreased activity of CA9 protein
CTD
PMID:15664814
NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159
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CAT
catalase
decreases activity
EXP
chloric acid results in decreased activity of CAT protein
CTD
PMID:21569832
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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GSR
glutathione-disulfide reductase
decreases activity
EXP
chloric acid results in decreased activity of GSR protein
CTD
PMID:21569832
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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ABCC1
ATP binding cassette subfamily C member 1 (ABCC1 blood group)
increases expression
ISO
Hypochlorous Acid results in increased expression of ABCC1 mRNA
CTD
PMID:19376150
NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257
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ABCD1
ATP binding cassette subfamily D member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABCD1 mRNA
CTD
PMID:19376150
NCBI chr X:153,724,856...153,744,755
Ensembl chr X:153,724,856...153,744,755
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ABHD16A
abhydrolase domain containing 16A, phospholipase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABHD16A mRNA
CTD
PMID:19376150
NCBI chr 6:31,686,955...31,703,324
Ensembl chr 6:31,686,955...31,703,356
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ACADS
acyl-CoA dehydrogenase short chain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACADS mRNA
CTD
PMID:19376150
NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008
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ACBD4
acyl-CoA binding domain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACBD4 mRNA
CTD
PMID:19376150
NCBI chr17:45,131,597...45,144,176
Ensembl chr17:45,132,600...45,144,181
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ACHE
acetylcholinesterase (Yt blood group)
multiple interactions decreases activity
EXP
[Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein; Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein]
CTD
PMID:12414318 PMID:36924976
NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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ADRM1
ADRM1 26S proteasome ubiquitin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of ADRM1 mRNA
CTD
PMID:19376150
NCBI chr20:62,302,896...62,308,862
Ensembl chr20:62,302,093...62,308,862
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AFP
alpha fetoprotein
increases expression
ISO
Hypochlorous Acid results in increased expression of AFP mRNA
CTD
PMID:19376150
NCBI chr 4:73,436,221...73,456,174
Ensembl chr 4:73,431,138...73,456,174
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AGRN
agrin
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AGRN mRNA
CTD
PMID:19376150
NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,119
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AKR1A1
aldo-keto reductase family 1 member A1
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1A1 mRNA
CTD
PMID:19376150
NCBI chr 1:45,550,826...45,570,049
Ensembl chr 1:45,550,543...45,570,049
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AKR1B1
aldo-keto reductase family 1 member B
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1B1 mRNA
CTD
PMID:19376150
NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
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AKR7A2
aldo-keto reductase family 7 member A2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AKR7A5 mRNA
CTD
PMID:19376150
NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,301,991...19,312,144
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ALDH1A3
aldehyde dehydrogenase 1 family member A3
increases expression
EXP
Hypochlorous Acid results in increased expression of ALDH1A3 mRNA
CTD
PMID:18156441
NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626
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AMOTL1
angiomotin like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AMOTL1 mRNA
CTD
PMID:19376150
NCBI chr11:94,706,460...94,876,748
Ensembl chr11:94,706,431...94,876,748
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AMPD1
adenosine monophosphate deaminase 1
increases activity multiple interactions
EXP
Hypochlorous Acid results in increased activity of AMPD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein]
CTD
PMID:36924976
NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618
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ANGEL2
angel homolog 2
increases expression
ISO
Hypochlorous Acid results in increased expression of ANGEL2 mRNA
CTD
PMID:19376150
NCBI chr 1:212,992,182...213,015,867
Ensembl chr 1:212,992,182...213,015,867
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ANKIB1
ankyrin repeat and IBR domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ANKIB1 mRNA
CTD
PMID:19376150
NCBI chr 7:92,245,974...92,401,383
Ensembl chr 7:92,245,974...92,401,383
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ANKRD11
ankyrin repeat domain containing 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD11 mRNA
CTD
PMID:19376150
NCBI chr16:89,267,630...89,490,561
Ensembl chr16:89,267,619...89,490,561
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ANKRD13D
ankyrin repeat domain 13D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD13D mRNA
CTD
PMID:19376150
NCBI chr11:67,289,303...67,302,484
Ensembl chr11:67,289,300...67,302,485
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AP1G2
adaptor related protein complex 1 subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP1G2 mRNA
CTD
PMID:19376150
NCBI chr14:23,559,567...23,567,791
Ensembl chr14:23,559,565...23,568,070
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AP3S2
adaptor related protein complex 3 subunit sigma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP3S2 mRNA
CTD
PMID:19376150
NCBI chr15:89,830,599...89,893,994
Ensembl chr15:89,830,599...89,894,638
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APEH
acylaminoacyl-peptide hydrolase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of APEH mRNA
CTD
PMID:19376150
NCBI chr 3:49,673,117...49,683,971
Ensembl chr 3:49,674,014...49,683,971
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APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1
multiple interactions increases activity increases expression
EXP
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein] Hypochlorous Acid results in increased activity of APEX1 protein
CTD
PMID:12231548
NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772
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API5
apoptosis inhibitor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of API5 mRNA
CTD
PMID:19376150
NCBI chr11:43,311,996...43,344,529
Ensembl chr11:43,311,963...43,344,529
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APOA1
apolipoprotein A1
multiple interactions
EXP
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein; Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]
CTD
PMID:33861588
NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622
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APPBP2
amyloid beta precursor protein binding protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of APPBP2 mRNA
CTD
PMID:19376150
NCBI chr17:60,443,158...60,526,242
Ensembl chr17:60,443,158...60,526,242
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ARCN1
archain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARCN1 mRNA
CTD
PMID:19376150
NCBI chr11:118,572,409...118,603,033
Ensembl chr11:118,572,390...118,603,033
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ARHGAP24
Rho GTPase activating protein 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGAP24 mRNA
CTD
PMID:19376150
NCBI chr 4:85,475,150...86,002,666
Ensembl chr 4:85,475,150...86,002,668
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ARHGEF1
Rho guanine nucleotide exchange factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGEF1 mRNA
CTD
PMID:19376150
NCBI chr19:41,883,184...41,930,141
Ensembl chr19:41,883,173...41,930,150
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ARIH1
ariadne RBR E3 ubiquitin protein ligase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARIH1 mRNA
CTD
PMID:19376150
NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
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ARL2
ARF like GTPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARL2 mRNA
CTD
PMID:19376150
NCBI chr11:65,014,160...65,022,184
Ensembl chr11:65,014,160...65,022,184
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ATXN3
ataxin 3
increases expression
ISO
Hypochlorous Acid results in increased expression of ATXN3 mRNA
CTD
PMID:19376150
NCBI chr14:92,044,775...92,106,582
Ensembl chr14:92,044,496...92,106,621
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B3GAT3
beta-1,3-glucuronyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of B3GAT3 mRNA
CTD
PMID:19376150
NCBI chr11:62,615,296...62,621,986
Ensembl chr11:62,615,296...62,622,154
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BACE1
beta-secretase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BACE1 mRNA
CTD
PMID:19376150
NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
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BCKDK
branched chain keto acid dehydrogenase kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BCKDK mRNA
CTD
PMID:19376150
NCBI chr16:31,108,386...31,117,640
Ensembl chr16:31,106,107...31,112,791
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BCLAF1
BCL2 associated transcription factor 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BCLAF1 mRNA
CTD
PMID:19376150
NCBI chr 6:136,256,627...136,289,846
Ensembl chr 6:136,256,627...136,289,851
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BHLHE40
basic helix-loop-helix family member e40
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BHLHE40 mRNA
CTD
PMID:19376150
NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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BLVRB
biliverdin reductase B
increases expression
ISO
Hypochlorous Acid results in increased expression of BLVRB mRNA
CTD
PMID:19376150
NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
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BRD4
bromodomain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD4 mRNA
CTD
PMID:19376150
NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
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BRD8
bromodomain containing 8
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD8 mRNA
CTD
PMID:19376150
NCBI chr 5:138,139,770...138,178,630
Ensembl chr 5:138,139,770...138,178,953
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BRI3
brain protein I3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRI3 mRNA
CTD
PMID:19376150
NCBI chr 7:98,281,686...98,323,430
Ensembl chr 7:98,252,379...98,310,441
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BRMS1
BRMS1 transcriptional repressor and anoikis regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRMS1 mRNA
CTD
PMID:19376150
NCBI chr11:66,337,339...66,345,104
Ensembl chr11:66,337,333...66,345,125
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BTBD2
BTB domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BTBD2 mRNA
CTD
PMID:19376150
NCBI chr19:1,985,448...2,015,714
Ensembl chr19:1,985,438...2,034,881
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BZW1
basic leucine zipper and W2 domains 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BZW1 mRNA
CTD
PMID:19376150
NCBI chr 2:200,811,589...200,827,338
Ensembl chr 2:200,810,594...200,827,338
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CA12
carbonic anhydrase 12
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAR12 mRNA
CTD
PMID:19376150
NCBI chr15:63,321,378...63,381,846
Ensembl chr15:63,321,378...63,381,846
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CAB39
calcium binding protein 39
increases expression
ISO
Hypochlorous Acid results in increased expression of CAB39 mRNA
CTD
PMID:19376150
NCBI chr 2:230,712,842...230,821,075
Ensembl chr 2:230,712,842...230,821,075
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CAMK1D
calcium/calmodulin dependent protein kinase ID
increases expression
ISO
Hypochlorous Acid results in increased expression of CAMK1D mRNA
CTD
PMID:19376150
NCBI chr10:12,349,547...12,835,545
Ensembl chr10:12,349,547...12,835,545
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CANX
calnexin
increases expression
ISO
Hypochlorous Acid results in increased expression of CANX mRNA
CTD
PMID:19376150
NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
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CAPN5
calpain 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAPN5 mRNA
CTD
PMID:19376150
NCBI chr11:77,066,971...77,126,155
Ensembl chr11:77,066,961...77,126,155
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CAT
catalase
multiple interactions increases activity increases expression
ISO EXP
CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased activity of CAT protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein] Hypochlorous Acid results in increased expression of CAT mRNA
CTD
PMID:17980396 PMID:19376150 PMID:36924976
NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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CCND3
cyclin D3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CCND3 mRNA
CTD
PMID:19376150
NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
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CD47
CD47 molecule
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CD47 mRNA
CTD
PMID:19376150
NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862
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CDC42
cell division cycle 42
increases expression
ISO
Hypochlorous Acid results in increased expression of CDC42 mRNA
CTD
PMID:19376150
NCBI chr 1:22,052,709...22,101,360
Ensembl chr 1:22,052,627...22,101,360
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CDCA7L
cell division cycle associated 7 like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDCA7L mRNA
CTD
PMID:19376150
NCBI chr 7:21,900,899...21,945,899
Ensembl chr 7:21,900,899...21,945,903
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CDK5RAP3
CDK5 regulatory subunit associated protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK5RAP3 mRNA
CTD
PMID:19376150
NCBI chr17:47,967,904...47,981,781
Ensembl chr17:47,967,810...47,981,781
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CDK6
cyclin dependent kinase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK6 mRNA
CTD
PMID:19376150
NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
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CDK7
cyclin dependent kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of CDK7 mRNA
CTD
PMID:19376150
NCBI chr 5:69,234,795...69,277,430
Ensembl chr 5:69,234,795...69,277,430
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CDS1
CDP-diacylglycerol synthase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDS1 mRNA
CTD
PMID:19376150
NCBI chr 4:84,583,127...84,651,334
Ensembl chr 4:84,583,127...84,651,334
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CDS2
CDP-diacylglycerol synthase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of CDS2 mRNA
CTD
PMID:19376150
NCBI chr20:5,127,008...5,197,887
Ensembl chr20:5,126,879...5,197,887
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CEP43
centrosomal protein 43
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CEP43 mRNA
CTD
PMID:19376150
NCBI chr 6:166,999,397...167,052,718
Ensembl chr 6:166,999,174...167,052,718
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CEP76
centrosomal protein 76
increases expression
ISO
Hypochlorous Acid results in increased expression of CEP76 mRNA
CTD
PMID:19376150
NCBI chr18:12,661,956...12,702,777
Ensembl chr18:12,661,833...12,702,777
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CERK
ceramide kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CERK mRNA
CTD
PMID:19376150
NCBI chr22:46,684,410...46,738,252
Ensembl chr22:46,684,410...46,738,252
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CHD3
chromodomain helicase DNA binding protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD3 mRNA
CTD
PMID:19376150
NCBI chr17:7,884,796...7,912,755
Ensembl chr17:7,884,796...7,912,760
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CHD4
chromodomain helicase DNA binding protein 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD4 mRNA
CTD
PMID:19376150
NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
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CHIT1
chitinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHIT1 mRNA
CTD
PMID:19376150
NCBI chr 1:203,216,079...203,230,099
Ensembl chr 1:203,212,827...203,273,641
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CHORDC1
cysteine and histidine rich domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CHORDC1 mRNA
CTD
PMID:19376150
NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077
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CLEC4D
C-type lectin domain family 4 member D
increases expression
ISO
Hypochlorous Acid results in increased expression of CLEC4D mRNA
CTD
PMID:19376150
NCBI chr12:8,513,503...8,531,696
Ensembl chr12:8,509,475...8,522,366
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CLN6
CLN6 transmembrane ER protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLN6 mRNA
CTD
PMID:19376150
NCBI chr15:68,206,992...68,257,211
Ensembl chr15:68,206,992...68,257,211
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CLTA
clathrin light chain A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLTA mRNA
CTD
PMID:19376150
NCBI chr 9:36,190,874...36,212,059
Ensembl chr 9:36,190,856...36,304,781
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CORO1A
coronin 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CORO1A mRNA
CTD
PMID:19376150
NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076
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CTDSP1
CTD small phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTDSP1 mRNA
CTD
PMID:19376150
NCBI chr 2:218,396,351...218,405,941
Ensembl chr 2:218,397,136...218,405,941
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CTNNBIP1
catenin beta interacting protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNNBIP1 mRNA
CTD
PMID:19376150
NCBI chr 1:9,848,276...9,910,269
Ensembl chr 1:9,848,276...9,910,336
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CTNS
cystinosin, lysosomal cystine transporter
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNS mRNA
CTD
PMID:19376150
NCBI chr17:3,636,459...3,663,103
Ensembl chr17:3,636,459...3,663,103
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CTSB
cathepsin B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTSB mRNA
CTD
PMID:19376150
NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
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CUL5
cullin 5
increases expression
ISO
Hypochlorous Acid results in increased expression of CUL5 mRNA
CTD
PMID:19376150
NCBI chr11:108,008,898...108,107,761
Ensembl chr11:108,008,898...108,107,761
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CYP20A1
cytochrome P450 family 20 subfamily A member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CYP20A1 mRNA
CTD
PMID:19376150
NCBI chr 2:203,239,018...203,306,026
Ensembl chr 2:203,238,977...203,306,026
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DAB2
DAB adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DAB2 mRNA
CTD
PMID:19376150
NCBI chr 5:39,371,677...39,424,980
Ensembl chr 5:39,371,675...39,462,300
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DDIT3
DNA damage inducible transcript 3
increases expression
ISO
Hypochlorous Acid results in increased expression of DDIT3 mRNA
CTD
PMID:19376150
NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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DDX10
DEAD-box helicase 10
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX10 mRNA
CTD
PMID:19376150
NCBI chr11:108,665,069...108,940,927
Ensembl chr11:108,665,058...108,940,999
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DDX3X
DEAD-box helicase 3 X-linked
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX3X mRNA
CTD
PMID:19376150
NCBI chr X:41,333,308...41,364,472
Ensembl chr X:41,333,348...41,364,472
G
DENND1A
DENN domain containing 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DENND1A mRNA
CTD
PMID:19376150
NCBI chr 9:123,379,658...123,930,126
Ensembl chr 9:123,379,654...123,930,152
G
DHX33
DEAH-box helicase 33
increases expression
ISO
Hypochlorous Acid results in increased expression of DHX33 mRNA
CTD
PMID:19376150
NCBI chr17:5,440,917...5,468,982
Ensembl chr17:5,440,917...5,468,982
G
DLST
dihydrolipoamide S-succinyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DLST mRNA
CTD
PMID:19376150
NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743
G
DNAJA2
DnaJ heat shock protein family (Hsp40) member A2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNAJA2 mRNA
CTD
PMID:19376150
NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674
G
DNMT1
DNA methyltransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DNMT1 mRNA
CTD
PMID:19376150
NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
G
DNMT3L
DNA methyltransferase 3 like
increases expression
ISO
Hypochlorous Acid results in increased expression of DNMT3L mRNA
CTD
PMID:19376150
NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216
G
DNTTIP2
deoxynucleotidyltransferase terminal interacting protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNTTIP2 mRNA
CTD
PMID:19376150
NCBI chr 1:93,866,284...93,879,206
Ensembl chr 1:93,866,284...93,879,918
G
DR1
down-regulator of transcription 1
increases expression
ISO
Hypochlorous Acid results in increased expression of DR1 mRNA
CTD
PMID:19376150
NCBI chr 1:93,345,907...93,369,493
Ensembl chr 1:93,345,907...93,369,493
G
DTNB
dystrobrevin beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTNB mRNA
CTD
PMID:19376150
NCBI chr 2:25,377,243...25,673,577
Ensembl chr 2:25,377,198...25,673,647
G
DTWD2
DTW domain containing 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DTWD2 mRNA
CTD
PMID:19376150
NCBI chr 5:118,836,074...118,988,547
Ensembl chr 5:118,836,074...118,988,547
G
DTX3
deltex E3 ubiquitin ligase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTX3 mRNA
CTD
PMID:19376150
NCBI chr12:57,604,824...57,609,802
Ensembl chr12:57,604,622...57,609,804
G
EEFSEC
eukaryotic elongation factor, selenocysteine-tRNA specific
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EEFSEC mRNA
CTD
PMID:19376150
NCBI chr 3:128,153,481...128,426,223
Ensembl chr 3:128,153,481...128,408,646
G
EGFR
epidermal growth factor receptor
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein
CTD
PMID:18156441
NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
G
EHMT2
euchromatic histone lysine methyltransferase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EHMT2 mRNA
CTD
PMID:19376150
NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698
G
EIF5
eukaryotic translation initiation factor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of EIF5 mRNA
CTD
PMID:19376150
NCBI chr14:103,334,237...103,345,025
Ensembl chr14:103,333,544...103,345,025
G
ELOA
elongin A
increases expression
ISO
Hypochlorous Acid results in increased expression of ELOA mRNA
CTD
PMID:19376150
NCBI chr 1:23,743,471...23,762,059
Ensembl chr 1:23,743,448...23,762,059
G
ERI3
ERI1 exoribonuclease family member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERI3 mRNA
CTD
PMID:19376150
NCBI chr 1:44,221,070...44,355,279
Ensembl chr 1:44,221,070...44,355,260
G
ERP29
endoplasmic reticulum protein 29
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERP29 mRNA
CTD
PMID:19376150
NCBI chr12:112,013,426...112,023,449
Ensembl chr12:112,013,348...112,023,449
G
ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ESCO1 mRNA
CTD
PMID:19376150
NCBI chr18:21,529,284...21,600,704
Ensembl chr18:21,529,281...21,600,884
G
ESD
esterase D
increases expression
ISO
Hypochlorous Acid results in increased expression of ESD mRNA
CTD
PMID:19376150
NCBI chr13:46,771,256...46,797,700
Ensembl chr13:46,771,256...46,797,420
G
EXOSC5
exosome component 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EXOSC5 mRNA
CTD
PMID:19376150
NCBI chr19:41,386,374...41,397,359
Ensembl chr19:41,386,371...41,397,362
G
FANCE
FA complementation group E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FANCE mRNA
CTD
PMID:19376150
NCBI chr 6:35,452,338...35,467,102
Ensembl chr 6:35,452,338...35,467,104
G
FASTK
Fas activated serine/threonine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FASTK mRNA
CTD
PMID:19376150
NCBI chr 7:151,076,624...151,080,809
Ensembl chr 7:151,076,624...151,080,866
G
FBXL3
F-box and leucine rich repeat protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of FBXL3 mRNA
CTD
PMID:19376150
NCBI chr13:77,005,260...77,027,159
Ensembl chr13:76,992,598...77,027,195
G
FBXW5
F-box and WD repeat domain containing 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW5 mRNA
CTD
PMID:19376150
NCBI chr 9:136,940,435...136,944,738
Ensembl chr 9:136,940,435...136,944,738
G
FBXW7
F-box and WD repeat domain containing 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW7 mRNA
CTD
PMID:19376150
NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
G
FGR
FGR proto-oncogene, Src family tyrosine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FGR mRNA
CTD
PMID:19376150
NCBI chr 1:27,612,064...27,635,185
Ensembl chr 1:27,612,064...27,635,185
G
FKTN
fukutin
increases expression
ISO
Hypochlorous Acid results in increased expression of FKTN mRNA
CTD
PMID:19376150
NCBI chr 9:105,558,130...105,641,118
Ensembl chr 9:105,558,122...105,653,820
G
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of FOS mRNA; Hypochlorous Acid results in increased expression of FOS protein
CTD
PMID:19376150
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
G
FOXRED1
FAD dependent oxidoreductase domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FOXRED1 mRNA
CTD
PMID:19376150
NCBI chr11:126,269,154...126,278,126
Ensembl chr11:126,269,024...126,278,131
G
FTL
ferritin light chain
increases expression
ISO
Hypochlorous Acid results in increased expression of FTL1 mRNA
CTD
PMID:19376150
NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,967,896
G
G6PD
glucose-6-phosphate dehydrogenase
decreases activity multiple interactions
EXP
Hypochlorous Acid results in decreased activity of G6PD protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]
CTD
PMID:36924976
NCBI chr X:154,531,390...154,547,569
Ensembl chr X:154,517,825...154,547,572
G
GADD45A
growth arrest and DNA damage inducible alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45A mRNA
CTD
PMID:19376150
NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
G
GADD45B
growth arrest and DNA damage inducible beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45B mRNA
CTD
PMID:19376150
NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,805
G
GADD45G
growth arrest and DNA damage inducible gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45G mRNA
CTD
PMID:19376150
NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
G
GALK1
galactokinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GALK1 mRNA
CTD
PMID:19376150
NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
G
GCLC
glutamate-cysteine ligase catalytic subunit
multiple interactions affects expression increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA] Hypochlorous Acid affects the expression of GCLC mRNA
CTD
PMID:17980396 PMID:18648578
NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
G
GCLM
glutamate-cysteine ligase modifier subunit
increases expression
EXP ISO
Hypochlorous Acid results in increased expression of GCLM mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
G
GMFB
glia maturation factor beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GMFB mRNA
CTD
PMID:19376150
NCBI chr14:54,474,485...54,488,980
Ensembl chr14:54,474,484...54,489,025
G
GNAI3
G protein subunit alpha i3
increases expression
ISO
Hypochlorous Acid results in increased expression of GNAI3 mRNA
CTD
PMID:19376150
NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195
G
GNB2
G protein subunit beta 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GNB2 mRNA
CTD
PMID:19376150
NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174
G
GOPC
golgi associated PDZ and coiled-coil motif containing
increases expression
ISO
Hypochlorous Acid results in increased expression of GOPC mRNA
CTD
PMID:19376150
NCBI chr 6:117,560,269...117,602,511
Ensembl chr 6:117,560,269...117,602,542
G
GPBP1
GC-rich promoter binding protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of GPBP1 mRNA
CTD
PMID:19376150
NCBI chr 5:57,174,059...57,264,679
Ensembl chr 5:57,173,948...57,264,679
G
GPX1
glutathione peroxidase 1
decreases expression multiple interactions increases activity
ISO EXP
Hypochlorous Acid results in decreased expression of GPX1 mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
G
GPX4
glutathione peroxidase 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GPX4 mRNA
CTD
PMID:19376150
NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791
G
GRN
granulin precursor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GRN mRNA
CTD
PMID:19376150
NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
G
GSR
glutathione-disulfide reductase
increases expression decreases activity multiple interactions
ISO EXP
Hypochlorous Acid results in increased expression of GSR mRNA Hypochlorous Acid results in decreased activity of GSR protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein]
CTD
PMID:17980396 PMID:36924976
NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
G
GSS
glutathione synthetase
increases expression
ISO
Hypochlorous Acid results in increased expression of GSS mRNA
CTD
PMID:17980396
NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
G
H2BC18
H2B clustered histone 18
increases expression
ISO
Hypochlorous Acid results in increased expression of H2BC18 mRNA
CTD
PMID:19376150
NCBI chr 1:149,782,689...149,812,370
Ensembl chr 1:149,782,689...149,812,373
G
HAGHL
hydroxyacylglutathione hydrolase like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAGHL mRNA
CTD
PMID:19376150
NCBI chr16:727,106...729,715
Ensembl chr16:726,936...735,525
G
HAUS4
HAUS augmin like complex subunit 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAUS4 mRNA
CTD
PMID:19376150
NCBI chr14:22,946,228...22,957,090
Ensembl chr14:22,946,228...22,957,161
G
HDAC10
histone deacetylase 10
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC10 mRNA
CTD
PMID:19376150
NCBI chr22:50,245,183...50,251,265
Ensembl chr22:50,245,183...50,251,405
G
HDAC5
histone deacetylase 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC5 mRNA
CTD
PMID:19376150
NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702
G
HDAC6
histone deacetylase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC6 mRNA
CTD
PMID:19376150
NCBI chr X:48,801,398...48,824,982
Ensembl chr X:48,801,377...48,824,982
G
HEXD
hexosaminidase D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HEXD mRNA
CTD
PMID:19376150
NCBI chr17:82,418,347...82,442,645
Ensembl chr17:82,418,318...82,442,645
G
HIPK2
homeodomain interacting protein kinase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK2 mRNA
CTD
PMID:19376150
NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
G
HIPK3
homeodomain interacting protein kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK3 mRNA
CTD
PMID:19376150
NCBI chr11:33,256,672...33,357,023
Ensembl chr11:33,256,672...33,357,023
G
HK1
hexokinase 1
decreases activity multiple interactions
EXP
Hypochlorous Acid results in decreased activity of HK1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein]
CTD
PMID:36924976
NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884
G
HMGA2
high mobility group AT-hook 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HMGA2 mRNA
CTD
PMID:19376150
NCBI chr12:65,824,460...65,966,291
Ensembl chr12:65,824,460...65,966,291
G
HMOX1
heme oxygenase 1
multiple interactions increases expression
EXP ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA] [Quercetin co-treated with Hypochlorous Acid] results in increased expression of HMOX1 protein Hypochlorous Acid results in increased expression of HMOX1 mRNA; Hypochlorous Acid results in increased expression of HMOX1 protein
CTD
PMID:17980396 PMID:18156441 PMID:19376150 PMID:24017971
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
G
HPCAL1
hippocalcin like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPCAL1 mRNA
CTD
PMID:19376150
NCBI chr 2:10,302,904...10,427,604
Ensembl chr 2:10,302,889...10,427,617
G
HPRT1
hypoxanthine phosphoribosyltransferase 1
increases mutagenesis
EXP
Hypochlorous Acid results in increased mutagenesis of HPRT1 gene
CTD
PMID:19892774
NCBI chr X:134,460,165...134,500,668
Ensembl chr X:134,460,165...134,520,513
G
HPS1
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPS1 mRNA
CTD
PMID:19376150
NCBI chr10:98,413,948...98,446,935
Ensembl chr10:98,410,939...98,446,963
G
HSP90AA1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of HSP90AA1 mRNA
CTD
PMID:19376150
NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
G
HSPA13
heat shock protein family A (Hsp70) member 13
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA13 mRNA
CTD
PMID:19376150
NCBI chr21:14,371,115...14,383,146
Ensembl chr21:14,371,115...14,383,484
G
HSPA1A
heat shock protein family A (Hsp70) member 1A
multiple interactions increases expression
EXP
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]
CTD
PMID:12231548
NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
G
HSPA1B
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA1B mRNA
CTD
PMID:19376150
NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
G
IFNG
interferon gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IFNG mRNA
CTD
PMID:19376150
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
G
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IKBKG mRNA
CTD
PMID:19376150
NCBI chr X:154,541,238...154,565,046
Ensembl chr X:154,541,199...154,565,046
G
IL10
interleukin 10
increases expression
ISO
Hypochlorous Acid results in increased expression of IL10 mRNA
CTD
PMID:19376150
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
G
IL1B
interleukin 1 beta
increases expression
ISO
Hypochlorous Acid results in increased expression of IL1B mRNA
CTD
PMID:19376150
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
G
IL6
interleukin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of IL6 mRNA
CTD
PMID:19376150
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
G
ING2
inhibitor of growth family member 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ING2 mRNA
CTD
PMID:19376150
NCBI chr 4:183,505,058...183,512,429
Ensembl chr 4:183,505,058...183,512,429
G
INTS7
integrator complex subunit 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of INTS7 mRNA
CTD
PMID:19376150
NCBI chr 1:211,940,403...212,035,557
Ensembl chr 1:211,940,399...212,035,557
G
INTS8
integrator complex subunit 8
increases expression
ISO
Hypochlorous Acid results in increased expression of INTS8 mRNA
CTD
PMID:19376150
NCBI chr 8:94,823,287...94,881,746
Ensembl chr 8:94,813,311...94,881,746
G
ITGB5
integrin subunit beta 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ITGB5 mRNA
CTD
PMID:19376150
NCBI chr 3:124,761,948...124,901,418
Ensembl chr 3:124,761,948...124,901,418
G
JAG1
jagged canonical Notch ligand 1
increases expression
ISO
Hypochlorous Acid results in increased expression of JAG1 mRNA
CTD
PMID:19376150
NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
G
JAK3
Janus kinase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of JAK3 mRNA
CTD
PMID:19376150
NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
G
KBTBD8
kelch repeat and BTB domain containing 8
increases expression
ISO
Hypochlorous Acid results in increased expression of KBTBD8 mRNA
CTD
PMID:19376150
NCBI chr 3:66,998,307...67,011,210
Ensembl chr 3:66,998,307...67,011,210
G
KEAP1
kelch like ECH associated protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KEAP1 mRNA
CTD
PMID:17980396
NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
G
KIF1B
kinesin family member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF1B mRNA
CTD
PMID:19376150
NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
G
KIF24
kinesin family member 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of KIF24 mRNA
CTD
PMID:19376150
NCBI chr 9:34,252,380...34,333,671
Ensembl chr 9:34,252,380...34,329,268
G
KIF3C
kinesin family member 3C
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF3C mRNA
CTD
PMID:19376150
NCBI chr 2:25,926,598...25,982,497
Ensembl chr 2:25,926,598...25,982,749
G
KIF5B
kinesin family member 5B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF5B mRNA
CTD
PMID:19376150
NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425
G
KPNA1
karyopherin subunit alpha 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA1 mRNA
CTD
PMID:19376150
NCBI chr 3:122,421,902...122,514,939
Ensembl chr 3:122,421,902...122,514,945
G
KPNA4
karyopherin subunit alpha 4
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA4 mRNA
CTD
PMID:19376150
NCBI chr 3:160,495,007...160,565,571
Ensembl chr 3:160,495,007...160,565,571
G
KRR1
KRR1 small subunit processome component homolog
increases expression
ISO
Hypochlorous Acid results in increased expression of KRR1 mRNA
CTD
PMID:19376150
NCBI chr12:75,490,863...75,511,609
Ensembl chr12:75,490,863...75,511,636
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LCAT
lecithin-cholesterol acyltransferase
multiple interactions
EXP
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein
CTD
PMID:33861588
NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131
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LDHA
lactate dehydrogenase A
increases activity multiple interactions
EXP
Hypochlorous Acid results in increased activity of LDHA protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]
CTD
PMID:36924976
NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425
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LIMD2
LIM domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LIMD2 mRNA
CTD
PMID:19376150
NCBI chr17:63,695,888...63,701,155
Ensembl chr17:63,695,888...63,701,172
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LMF1
lipase maturation factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LMF1 mRNA
CTD
PMID:19376150
NCBI chr16:853,634...981,613
Ensembl chr16:853,634...981,318
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LOXL3
lysyl oxidase like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LOXL3 mRNA
CTD
PMID:19376150
NCBI chr 2:74,532,258...74,555,702
Ensembl chr 2:74,532,258...74,555,690
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LRP1
LDL receptor related protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LRP1 mRNA
CTD
PMID:19376150
NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
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LRRC8D
leucine rich repeat containing 8 VRAC subunit D
increases expression
ISO
Hypochlorous Acid results in increased expression of LRRC8D mRNA
CTD
PMID:19376150
NCBI chr 1:89,821,032...89,936,611
Ensembl chr 1:89,821,014...89,936,611
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MAFF
MAF bZIP transcription factor F
increases expression
EXP
Hypochlorous Acid results in increased expression of MAFF mRNA
CTD
PMID:18156441
NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
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MAFG
MAF bZIP transcription factor G
increases expression
EXP
Hypochlorous Acid results in increased expression of MAFG mRNA
CTD
PMID:18156441
NCBI chr17:81,918,270...81,931,244
Ensembl chr17:81,918,270...81,927,735
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MAN1A2
mannosidase alpha class 1A member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of MAN1A2 mRNA
CTD
PMID:19376150
NCBI chr 1:117,367,449...117,528,872
Ensembl chr 1:117,367,449...117,528,872
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MAN1C1
mannosidase alpha class 1C member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN1C1 mRNA
CTD
PMID:19376150
NCBI chr 1:25,616,791...25,784,450
Ensembl chr 1:25,616,791...25,784,450
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MAN2C1
mannosidase alpha class 2C member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN2C1 mRNA
CTD
PMID:19376150
NCBI chr15:75,355,792...75,368,607
Ensembl chr15:75,355,207...75,368,612
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MAP3K7
mitogen-activated protein kinase kinase kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of MAP3K7 mRNA
CTD
PMID:19376150
NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
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MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAP4K1 mRNA
CTD
PMID:19376150
NCBI chr19:38,587,641...38,617,953
Ensembl chr19:38,587,641...38,618,882
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MAPK1
mitogen-activated protein kinase 1
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD
PMID:18156441
NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK10
mitogen-activated protein kinase 10
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK10 protein
CTD
PMID:18156441
NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625
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MAPK3
mitogen-activated protein kinase 3
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD
PMID:18156441
NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK6
mitogen-activated protein kinase 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MAPK6 mRNA
CTD
PMID:19376150
NCBI chr15:51,971,825...52,067,375
Ensembl chr15:51,952,106...52,067,375
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MAPK8
mitogen-activated protein kinase 8
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD
PMID:18156441
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPK9
mitogen-activated protein kinase 9
multiple interactions
EXP
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK9 protein
CTD
PMID:18156441
NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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MARCHF2
membrane associated ring-CH-type finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MARCHF2 mRNA
CTD
PMID:19376150
NCBI chr19:8,413,305...8,439,017
Ensembl chr19:8,413,270...8,439,017
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ME1
malic enzyme 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ME1 mRNA
CTD
PMID:19376150
NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
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MFAP1
microfibril associated protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of MFAP1 mRNA
CTD
PMID:19376150
NCBI chr15:43,804,492...43,824,690
Ensembl chr15:43,804,492...43,824,690
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MFSD13A
major facilitator superfamily domain containing 13A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MFSD13A mRNA
CTD
PMID:19376150
NCBI chr10:102,461,395...102,477,045
Ensembl chr10:102,461,395...102,477,045
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MIIP
migration and invasion inhibitory protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MIIP mRNA
CTD
PMID:19376150
NCBI chr 1:12,019,498...12,032,045
Ensembl chr 1:12,019,466...12,032,045
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MOB1A
MOB kinase activator 1A
increases expression
ISO
Hypochlorous Acid results in increased expression of MOB1A mRNA
CTD
PMID:19376150
NCBI chr 2:74,152,528...74,178,879
Ensembl chr 2:74,152,528...74,178,898
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MPO
myeloperoxidase
multiple interactions increases abundance increases chemical synthesis
EXP
4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; MitoTEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; TEMPOL-H inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]
CTD
PMID:7772042 PMID:20939553 PMID:34085520 PMID:35575633
NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
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MRPL4
mitochondrial ribosomal protein L4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MRPL4 mRNA
CTD
PMID:19376150
NCBI chr19:10,251,951...10,260,055
Ensembl chr19:10,251,901...10,260,055
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MSRB1
methionine sulfoxide reductase B1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MSRB1 mRNA
CTD
PMID:19376150
NCBI chr16:1,938,229...1,943,199
Ensembl chr16:1,938,229...1,943,199
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MTA1
metastasis associated 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA1 mRNA
CTD
PMID:19376150
NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729
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MTA3
metastasis associated 1 family member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA3 mRNA
CTD
PMID:19376150
NCBI chr 2:42,494,110...42,756,946
Ensembl chr 2:42,494,569...42,756,947
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MTARC2
mitochondrial amidoxime reducing component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTARC2 mRNA
CTD
PMID:19376150
NCBI chr 1:220,748,322...220,784,815
Ensembl chr 1:220,748,225...220,784,815
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MTDH
metadherin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTDH mRNA
CTD
PMID:19376150
NCBI chr 8:97,644,184...97,730,260
Ensembl chr 8:97,644,184...97,730,260
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MTMR6
myotubularin related protein 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MTMR6 mRNA
CTD
PMID:19376150
NCBI chr13:25,246,222...25,287,488
Ensembl chr13:25,246,222...25,287,510
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MTPN
myotrophin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTPN mRNA
CTD
PMID:19376150
NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
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MUC16
mucin 16, cell surface associated
increases expression
ISO
Hypochlorous Acid results in increased expression of MUC16 mRNA
CTD
PMID:19376150
NCBI chr19:8,848,844...9,065,751
Ensembl chr19:8,848,844...9,010,390
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MVD
mevalonate diphosphate decarboxylase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MVD mRNA
CTD
PMID:19376150
NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161
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MYH9
myosin heavy chain 9
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYH9 mRNA
CTD
PMID:19376150
NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010
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MYO1F
myosin IF
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO1F mRNA
CTD
PMID:19376150
NCBI chr19:8,520,778...8,577,442
Ensembl chr19:8,517,463...8,577,442
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MYO9B
myosin IXB
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO9B mRNA
CTD
PMID:19376150
NCBI chr19:17,075,777...17,213,286
Ensembl chr19:17,075,777...17,214,537
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NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of NAA15 mRNA
CTD
PMID:19376150
NCBI chr 4:139,301,505...139,391,384
Ensembl chr 4:139,301,446...139,420,033
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NCAPH2
non-SMC condensin II complex subunit H2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NCAPH2 mRNA
CTD
PMID:19376150
NCBI chr22:50,508,224...50,524,780
Ensembl chr22:50,508,224...50,524,780
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NDUFS2
NADH:ubiquinone oxidoreductase core subunit S2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS2 mRNA
CTD
PMID:19376150
NCBI chr 1:161,197,417...161,214,395
Ensembl chr 1:161,197,104...161,214,723
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NDUFS7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS7 mRNA
CTD
PMID:19376150
NCBI chr19:1,383,907...1,395,584
Ensembl chr19:1,383,527...1,395,589
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NELFE
negative elongation factor complex member E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELFE mRNA
CTD
PMID:19376150
NCBI chr 6:31,952,087...31,958,971
Ensembl chr 6:31,952,087...31,959,038
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NELL1
neural EGFL like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELL1 mRNA
CTD
PMID:19376150
NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686
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NFE2L2
NFE2 like bZIP transcription factor 2
multiple interactions increases expression affects response to substance
EXP ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased expression of NFE2L2 protein Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] NFE2L2 protein affects the susceptibility to Hypochlorous Acid
CTD
PMID:17980396 PMID:18156441
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NOL11
nucleolar protein 11
increases expression
ISO
Hypochlorous Acid results in increased expression of NOL11 mRNA
CTD
PMID:19376150
NCBI chr17:67,717,936...67,744,531
Ensembl chr17:67,717,931...67,744,531
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NQO1
NAD(P)H quinone dehydrogenase 1
increases expression affects expression
EXP ISO
Hypochlorous Acid results in increased expression of NQO1 mRNA Hypochlorous Acid affects the expression of NQO1 mRNA
CTD
PMID:17980396 PMID:18156441 PMID:18648578 PMID:19376150
NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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NR1D1
nuclear receptor subfamily 1 group D member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NR1D1 mRNA
CTD
PMID:19376150
NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
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NRP1
neuropilin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of NRP1 mRNA
CTD
PMID:19376150
NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262
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NUP54
nucleoporin 54
increases expression
ISO
Hypochlorous Acid results in increased expression of NUP54 mRNA
CTD
PMID:19376150
NCBI chr 4:76,114,664...76,148,397
Ensembl chr 4:76,107,562...76,148,485
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OTUD4
OTU deubiquitinase 4
increases expression
ISO
Hypochlorous Acid results in increased expression of OTUD4 mRNA
CTD
PMID:19376150
NCBI chr 4:145,133,650...145,180,589
Ensembl chr 4:145,110,838...145,180,589
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OVGP1
oviductal glycoprotein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of OVGP1 mRNA
CTD
PMID:19376150
NCBI chr 1:111,414,319...111,427,735
Ensembl chr 1:111,414,319...111,427,735
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P3H3
prolyl 3-hydroxylase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of P3H3 mRNA
CTD
PMID:19376150
NCBI chr12:6,828,407...6,839,847
Ensembl chr12:6,828,407...6,839,847
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PACSIN3
protein kinase C and casein kinase substrate in neurons 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PACSIN3 mRNA
CTD
PMID:19376150
NCBI chr11:47,177,522...47,186,434
Ensembl chr11:47,177,522...47,186,443
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PAFAH1B2
platelet activating factor acetylhydrolase 1b catalytic subunit 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PAFAH1B2 mRNA
CTD
PMID:19376150
NCBI chr11:117,144,287...117,178,173
Ensembl chr11:117,144,284...117,176,894
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PAK1IP1
PAK1 interacting protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PAK1IP1 mRNA
CTD
PMID:19376150
NCBI chr 6:10,690,865...10,709,782
Ensembl chr 6:10,694,972...10,709,782
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PAPOLA
poly(A) polymerase alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PAPOLA mRNA
CTD
PMID:19376150
NCBI chr14:96,502,376...96,567,116
Ensembl chr14:96,501,433...96,567,116
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PARVB
parvin beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PARVB mRNA
CTD
PMID:19376150
NCBI chr22:43,999,211...44,172,939
Ensembl chr22:43,999,211...44,172,939
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PCDHGC3
protocadherin gamma subfamily C, 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PCDHGC3 mRNA
CTD
PMID:19376150
NCBI chr 5:141,475,966...141,512,975
Ensembl chr 5:141,475,947...141,512,977
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PCGF2
polycomb group ring finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PCGF2 mRNA
CTD
PMID:19376150
NCBI chr17:38,733,898...38,749,792
Ensembl chr17:38,733,898...38,749,817
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PEX6
peroxisomal biogenesis factor 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PEX6 mRNA
CTD
PMID:19376150
NCBI chr 6:42,963,865...42,979,181
Ensembl chr 6:42,963,865...42,979,181
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PGRMC2
progesterone receptor membrane component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PGRMC2 mRNA
CTD
PMID:19376150
NCBI chr 4:128,269,242...128,287,813
Ensembl chr 4:128,269,237...128,288,829
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PHKA2
phosphorylase kinase regulatory subunit alpha 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKA2 mRNA
CTD
PMID:19376150
NCBI chr X:18,892,298...18,984,114
Ensembl chr X:18,892,298...18,984,114
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PHKG2
phosphorylase kinase catalytic subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKG2 mRNA
CTD
PMID:19376150
NCBI chr16:30,748,425...30,761,176
Ensembl chr16:30,748,293...30,761,176
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PHPT1
phosphohistidine phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHPT1 mRNA
CTD
PMID:19376150
NCBI chr 9:136,849,409...136,851,024
Ensembl chr 9:136,848,724...136,851,027
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PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PIK3C2A mRNA
CTD
PMID:19376150
NCBI chr11:17,086,575...17,207,986
Ensembl chr11:17,077,730...17,207,986
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PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PKMYT1 mRNA
CTD
PMID:19376150
NCBI chr16:2,972,808...2,980,446
Ensembl chr16:2,968,024...2,980,479
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PLCB3
phospholipase C beta 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLCB3 mRNA
CTD
PMID:19376150
NCBI chr11:64,251,530...64,269,452
Ensembl chr11:64,251,530...64,269,150
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PLXNB2
plexin B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLXNB2 mRNA
CTD
PMID:19376150
NCBI chr22:50,274,979...50,307,646
Ensembl chr22:50,274,979...50,307,646
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PNKD
PNKD metallo-beta-lactamase domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PNKD mRNA
CTD
PMID:19376150
NCBI chr 2:218,270,519...218,346,793
Ensembl chr 2:218,269,651...218,346,793
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POLD1
DNA polymerase delta 1, catalytic subunit
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLD1 mRNA
CTD
PMID:19376150
NCBI chr19:50,384,323...50,418,018
Ensembl chr19:50,384,204...50,418,018
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POLL
DNA polymerase lambda
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLL mRNA
CTD
PMID:19376150
NCBI chr10:101,578,882...101,588,270
Ensembl chr10:101,578,882...101,588,270
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PON1
paraoxonase 1
decreases activity increases oxidation multiple interactions
EXP
Hypochlorous Acid results in decreased activity of PON1 protein Hypochlorous Acid results in increased oxidation of PON1 protein Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]
CTD
PMID:14671042 PMID:15104111
NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
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PPFIA4
PTPRF interacting protein alpha 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPFIA4 mRNA
CTD
PMID:19376150
NCBI chr 1:203,026,491...203,078,736
Ensembl chr 1:203,026,491...203,078,740
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PPOX
protoporphyrinogen oxidase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPOX mRNA
CTD
PMID:19376150
NCBI chr 1:161,165,728...161,178,013
Ensembl chr 1:161,166,056...161,178,013
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PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPP2R1A mRNA
CTD
PMID:19376150
NCBI chr19:52,190,052...52,229,518
Ensembl chr19:52,170,936...52,229,518
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PRDX1
peroxiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PRDX1 mRNA
CTD
PMID:19376150
NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
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PRDX5
peroxiredoxin 5
multiple interactions decreases activity
EXP
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of PRDX5 protein]
CTD
PMID:36924976
NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
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PRKAR2B
protein kinase cAMP-dependent type II regulatory subunit beta
increases expression
ISO
Hypochlorous Acid results in increased expression of PRKAR2B mRNA
CTD
PMID:19376150
NCBI chr 7:107,044,705...107,161,811
Ensembl chr 7:107,044,705...107,161,811
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PROCR
protein C receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PROCR mRNA
CTD
PMID:19376150
NCBI chr20:35,171,096...35,216,259
Ensembl chr20:35,172,072...35,216,240
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PSMA7
proteasome 20S subunit alpha 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMA7 mRNA
CTD
PMID:19376150
NCBI chr20:62,136,733...62,143,394
Ensembl chr20:62,136,733...62,143,440
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PSMB3
proteasome 20S subunit beta 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMB3 mRNA
CTD
PMID:19376150
NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
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PSMC1
proteasome 26S subunit, ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC1 mRNA
CTD
PMID:19376150
NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
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PSMC2
proteasome 26S subunit, ATPase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC2 mRNA
CTD
PMID:19376150
NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
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PSMD1
proteasome 26S subunit, non-ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD1 mRNA
CTD
PMID:19376150
NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,845...231,173,116
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PSMD11
proteasome 26S subunit, non-ATPase 11
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD11 mRNA
CTD
PMID:19376150
NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319
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PSMD5
proteasome 26S subunit, non-ATPase 5
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD5 mRNA
CTD
PMID:19376150
NCBI chr 9:120,816,053...120,842,922
Ensembl chr 9:120,815,496...120,842,951
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PSMD7
proteasome 26S subunit, non-ATPase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD7 mRNA
CTD
PMID:19376150
NCBI chr16:74,296,814...74,306,288
Ensembl chr16:74,296,814...74,306,288
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PTBP3
polypyrimidine tract binding protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTBP3 mRNA
CTD
PMID:19376150
NCBI chr 9:112,217,715...112,379,882
Ensembl chr 9:112,217,716...112,333,664
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PTGES2
prostaglandin E synthase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTGES2 mRNA
CTD
PMID:19376150
NCBI chr 9:128,120,693...128,128,440
Ensembl chr 9:128,120,693...128,128,462
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PTGES3
prostaglandin E synthase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGES3 mRNA
CTD
PMID:19376150
NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
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PTGIR
prostaglandin I2 receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGIR mRNA
CTD
PMID:19376150
NCBI chr19:46,610,687...46,625,089
Ensembl chr19:46,618,550...46,625,089
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PTOV1
PTOV1 extended AT-hook containing adaptor protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTOV1 mRNA
CTD
PMID:19376150
NCBI chr19:49,850,705...49,860,742
Ensembl chr19:49,850,735...49,860,744
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PTP4A3
protein tyrosine phosphatase 4A3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTP4A3 mRNA
CTD
PMID:19376150
NCBI chr 8:141,392,021...141,432,454
Ensembl chr 8:141,391,995...141,432,454
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PTPN12
protein tyrosine phosphatase non-receptor type 12
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN12 mRNA
CTD
PMID:19376150
NCBI chr 7:77,537,295...77,640,069
Ensembl chr 7:77,537,295...77,640,069
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PTPN14
protein tyrosine phosphatase non-receptor type 14
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN14 mRNA
CTD
PMID:19376150
NCBI chr 1:214,348,700...214,551,602
Ensembl chr 1:214,348,700...214,552,449
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PWWP2B
PWWP domain containing 2B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PWWP2B mRNA
CTD
PMID:19376150
NCBI chr10:132,397,200...132,417,859
Ensembl chr10:132,397,168...132,417,859
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RAB10
RAB10, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB10 mRNA
CTD
PMID:19376150
NCBI chr 2:26,033,285...26,137,454
Ensembl chr 2:26,034,084...26,137,454
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RAB18
RAB18, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB18 mRNA
CTD
PMID:19376150
NCBI chr10:27,504,304...27,542,239
Ensembl chr10:27,504,174...27,545,117
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RAB22A
RAB22A, member RAS oncogene family
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RAB22A mRNA
CTD
PMID:19376150
NCBI chr20:58,309,715...58,367,507
Ensembl chr20:58,309,715...58,367,507
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RABEP1
rabaptin, RAB GTPase binding effector protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RABEP1 mRNA
CTD
PMID:19376150
NCBI chr17:5,282,284...5,386,340
Ensembl chr17:5,282,265...5,386,340
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RASSF4
Ras association domain family member 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RASSF4 mRNA
CTD
PMID:19376150
NCBI chr10:44,959,802...44,995,891
Ensembl chr10:44,959,407...44,995,891
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RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RBCK1 mRNA
CTD
PMID:19376150
NCBI chr20:408,299...432,139
Ensembl chr20:407,498...432,139
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RBM18
RNA binding motif protein 18
increases expression
ISO
Hypochlorous Acid results in increased expression of RBM18 mRNA
CTD
PMID:19376150
NCBI chr 9:122,237,622...122,264,840
Ensembl chr 9:122,237,622...122,264,840
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RBX1
ring-box 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RBX1 mRNA
CTD
PMID:19376150
NCBI chr22:40,951,378...40,973,309
Ensembl chr22:40,951,347...40,973,309
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RDX
radixin
increases expression
ISO
Hypochlorous Acid results in increased expression of RDX mRNA
CTD
PMID:19376150
NCBI chr11:110,174,922...110,296,614
Ensembl chr11:109,864,295...110,296,712
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REEP6
receptor accessory protein 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of REEP6 mRNA
CTD
PMID:19376150
NCBI chr19:1,491,181...1,497,927
Ensembl chr19:1,491,166...1,497,927
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RGL1
ral guanine nucleotide dissociation stimulator like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL1 mRNA
CTD
PMID:19376150
NCBI chr 1:183,636,109...183,928,532
Ensembl chr 1:183,636,085...183,928,532
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RGL2
ral guanine nucleotide dissociation stimulator like 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL2 mRNA
CTD
PMID:19376150
NCBI chr 6:33,291,654...33,301,612
Ensembl chr 6:33,291,654...33,298,942
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RIC8A
RIC8 guanine nucleotide exchange factor A
increases expression
ISO
Hypochlorous Acid results in increased expression of RIC8A mRNA
CTD
PMID:19376150
NCBI chr11:207,708...215,113
Ensembl chr11:207,708...215,113
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RIOK3
RIO kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of RIOK3 mRNA
CTD
PMID:19376150
NCBI chr18:23,453,287...23,483,140
Ensembl chr18:23,453,287...23,486,603
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RNASEH1
ribonuclease H1
increases expression
ISO
Hypochlorous Acid results in increased expression of RNASEH1 mRNA
CTD
PMID:19376150
NCBI chr 2:3,531,813...3,558,333
Ensembl chr 2:3,541,430...3,558,333
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RNF115
ring finger protein 115
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF115 mRNA
CTD
PMID:19376150
NCBI chr 1:145,738,868...145,824,095
Ensembl chr 1:145,738,868...145,824,095
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RNF128
ring finger protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF128 mRNA
CTD
PMID:19376150
NCBI chr X:106,693,838...106,797,016
Ensembl chr X:106,693,794...106,797,016
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RNF157
ring finger protein 157
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF157 mRNA
CTD
PMID:19376150
NCBI chr17:76,142,474...76,240,493
Ensembl chr17:76,142,465...76,240,493
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RNF183
ring finger protein 183
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF183 mRNA
CTD
PMID:19376150
NCBI chr 9:113,297,093...113,303,376
Ensembl chr 9:113,297,093...113,303,376
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RNF26
ring finger protein 26
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF26 mRNA
CTD
PMID:19376150
NCBI chr11:119,334,527...119,337,309
Ensembl chr11:119,334,527...119,337,309
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RNF4
ring finger protein 4
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF4 mRNA
CTD
PMID:19376150
NCBI chr 4:2,469,106...2,515,857
Ensembl chr 4:2,462,220...2,515,857
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ROCK1
Rho associated coiled-coil containing protein kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ROCK1 mRNA
CTD
PMID:19376150
NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,944,612...21,111,813
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RPF1
ribosome production factor 1 homolog
increases expression
ISO
Hypochlorous Acid results in increased expression of BXDC5 mRNA
CTD
PMID:19376150
NCBI chr 1:84,479,266...84,498,352
Ensembl chr 1:84,479,259...84,498,352
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RPL35
ribosomal protein L35
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPL35 mRNA
CTD
PMID:19376150
NCBI chr 9:124,857,883...124,861,957
Ensembl chr 9:124,857,880...124,861,981
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RPS6KB2
ribosomal protein S6 kinase B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPS6KB2 mRNA
CTD
PMID:19376150
NCBI chr11:67,428,494...67,435,401
Ensembl chr11:67,428,460...67,435,401
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RSL1D1
ribosomal L1 domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RSL1D1 mRNA
CTD
PMID:19376150
NCBI chr16:11,833,850...11,851,542
Ensembl chr16:11,833,850...11,851,580
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RUVBL2
RuvB like AAA ATPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RUVBL2 mRNA
CTD
PMID:19376150
NCBI chr19:48,993,448...49,015,995
Ensembl chr19:48,993,562...49,015,970
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RWDD2A
RWD domain containing 2A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RWDD2A mRNA
CTD
PMID:19376150
NCBI chr 6:83,193,357...83,198,935
Ensembl chr 6:83,193,357...83,198,935
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SATB2
SATB homeobox 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SATB2 mRNA
CTD
PMID:19376150
NCBI chr 2:199,269,500...199,471,266
Ensembl chr 2:199,269,505...199,471,266
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SBF1
SET binding factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SBF1 mRNA
CTD
PMID:19376150
NCBI chr22:50,445,000...50,475,035
Ensembl chr22:50,443,219...50,483,923
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SCAND1
SCAN domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SCAND1 mRNA
CTD
PMID:19376150
NCBI chr20:35,953,624...35,959,472
Ensembl chr20:35,953,617...35,959,472
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SDC3
syndecan 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SDC3 mRNA
CTD
PMID:19376150
NCBI chr 1:30,869,466...30,909,735
Ensembl chr 1:30,869,466...30,908,758
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SEC63
SEC63 homolog, protein translocation regulator
increases expression
ISO
Hypochlorous Acid results in increased expression of SEC63 mRNA
CTD
PMID:19376150
NCBI chr 6:107,867,756...107,958,208
Ensembl chr 6:107,867,756...107,958,208
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SELPLG
selectin P ligand
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SELPLG mRNA
CTD
PMID:19376150
NCBI chr12:108,621,895...108,633,894
Ensembl chr12:108,620,413...108,633,894
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SEMA5A
semaphorin 5A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SEMA5A mRNA
CTD
PMID:19376150
NCBI chr 5:9,035,033...9,546,075
Ensembl chr 5:9,035,033...9,546,075
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SERGEF
secretion regulating guanine nucleotide exchange factor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SERGEF mRNA
CTD
PMID:19376150
NCBI chr11:17,788,048...18,013,047
Ensembl chr11:17,788,048...18,013,047
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SERINC1
serine incorporator 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERINC1 mRNA
CTD
PMID:19376150
NCBI chr 6:122,443,351...122,471,807
Ensembl chr 6:122,443,351...122,471,807
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SERPINB9
serpin family B member 9
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINB9 mRNA
CTD
PMID:19376150
NCBI chr 6:2,887,270...2,903,309
Ensembl chr 6:2,887,173...2,903,309
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SERPINE1
serpin family E member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINE1 mRNA
CTD
PMID:19376150
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SETD6
SET domain containing 6, protein lysine methyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SETD6 mRNA
CTD
PMID:19376150
NCBI chr16:58,515,479...58,523,842
Ensembl chr16:58,515,479...58,523,842
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SH2B2
SH2B adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH2B2 mRNA
CTD
PMID:19376150
NCBI chr 7:102,285,141...102,321,711
Ensembl chr 7:102,285,091...102,321,711
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SH3BP1
SH3 domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH3BP1 mRNA
CTD
PMID:19376150
NCBI chr22:37,639,669...37,656,117
Ensembl chr22:37,634,654...37,656,117
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SIGIRR
single Ig and TIR domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIGIRR mRNA
CTD
PMID:19376150
NCBI chr11:405,716...417,397
Ensembl chr11:405,715...417,455
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SIPA1L1
signal induced proliferation associated 1 like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIPA1L1 mRNA
CTD
PMID:19376150
NCBI chr14:71,320,476...71,741,209
Ensembl chr14:71,320,449...71,741,229
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SLA
Src like adaptor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLA mRNA
CTD
PMID:19376150
NCBI chr 8:133,036,728...133,102,602
Ensembl chr 8:133,036,728...133,102,912
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SLC20A1
solute carrier family 20 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC20A1 mRNA
CTD
PMID:19376150
NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825
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SLC23A2
solute carrier family 23 member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC23A2 mRNA
CTD
PMID:19376150
NCBI chr20:4,852,358...5,010,313
Ensembl chr20:4,852,356...5,010,293
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SLC25A1
solute carrier family 25 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A1 mRNA
CTD
PMID:19376150
NCBI chr22:19,175,581...19,178,736
Ensembl chr22:19,175,581...19,178,739
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SLC25A12
solute carrier family 25 member 12
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC25A12 mRNA
CTD
PMID:19376150
NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859
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SLC25A28
solute carrier family 25 member 28
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A28 mRNA
CTD
PMID:19376150
NCBI chr10:99,610,522...99,659,286
Ensembl chr10:99,610,519...99,622,793
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SLC25A39
solute carrier family 25 member 39
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A39 mRNA
CTD
PMID:19376150
NCBI chr17:44,319,628...44,324,823
Ensembl chr17:44,319,625...44,324,870
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SLC35B2
solute carrier family 35 member B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35B2 mRNA
CTD
PMID:19376150
NCBI chr 6:44,254,101...44,257,890
Ensembl chr 6:44,254,096...44,257,890
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SLC35C2
solute carrier family 35 member C2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35C2 mRNA
CTD
PMID:19376150
NCBI chr20:46,345,984...46,364,425
Ensembl chr20:46,345,980...46,364,458
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SLC39A6
solute carrier family 39 member 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC39A6 mRNA
CTD
PMID:19376150
NCBI chr18:36,108,531...36,129,340
Ensembl chr18:36,108,531...36,129,385
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SLC40A1
solute carrier family 40 member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC40A1 mRNA
CTD
PMID:19376150
NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
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SLC7A11
solute carrier family 7 member 11
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC7A11 mRNA
CTD
PMID:19376150
NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SLK
STE20 like kinase
increases expression
ISO
Hypochlorous Acid results in increased expression of SLK mRNA
CTD
PMID:19376150
NCBI chr10:103,967,140...104,029,233
Ensembl chr10:103,967,140...104,029,233
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SLMAP
sarcolemma associated protein
increases expression
ISO
Hypochlorous Acid results in increased expression of SLMAP mRNA
CTD
PMID:19376150
NCBI chr 3:57,756,309...57,930,013
Ensembl chr 3:57,755,450...57,930,003
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SMARCA5
SNF2 related chromatin remodeling ATPase 5
increases expression
ISO
Hypochlorous Acid results in increased expression of SMARCA5 mRNA
CTD
PMID:19376150
NCBI chr 4:143,513,702...143,557,486
Ensembl chr 4:143,513,702...143,557,486
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SMARCD2
SWI/SNF related BAF chromatin remodeling complex subunit D2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMARCD2 mRNA
CTD
PMID:19376150
NCBI chr17:63,832,081...63,842,685
Ensembl chr17:63,832,081...63,843,065
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SMYD1
SET and MYND domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMYD1 mRNA
CTD
PMID:19376150
NCBI chr 2:88,067,825...88,113,384
Ensembl chr 2:88,067,825...88,113,384
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SMYD4
SET and MYND domain containing 4
increases expression
ISO
Hypochlorous Acid results in increased expression of SMYD4 mRNA
CTD
PMID:19376150
NCBI chr17:1,779,485...1,829,902
Ensembl chr17:1,779,485...1,830,634
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SNRPA
small nuclear ribonucleoprotein polypeptide A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNRPA mRNA
CTD
PMID:19376150
NCBI chr19:40,751,203...40,765,389
Ensembl chr19:40,750,637...40,765,389
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SNX17
sorting nexin 17
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNX17 mRNA
CTD
PMID:19376150
NCBI chr 2:27,370,616...27,377,535
Ensembl chr 2:27,370,496...27,377,535
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SNX6
sorting nexin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SNX6 mRNA
CTD
PMID:19376150
NCBI chr14:34,561,093...34,630,148
Ensembl chr14:34,561,093...34,630,160
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SOD1
superoxide dismutase 1
increases expression multiple interactions increases activity
ISO EXP
Hypochlorous Acid results in increased expression of SOD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of SOD1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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SQSTM1
sequestosome 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SQSTM1 mRNA
CTD
PMID:19376150
NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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SRXN1
sulfiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SRXN1 mRNA
CTD
PMID:19376150
NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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SSB
small RNA binding exonuclease protection factor La
increases expression
ISO
Hypochlorous Acid results in increased expression of SSB mRNA
CTD
PMID:19376150
NCBI chr 2:169,798,871...169,812,064
Ensembl chr 2:169,791,933...169,812,064
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ST14
ST14 transmembrane serine protease matriptase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST14 mRNA
CTD
PMID:19376150
NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362
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ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST3GAL3 mRNA
CTD
PMID:19376150
NCBI chr 1:43,707,536...43,931,159
Ensembl chr 1:43,705,824...43,931,165
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STIMATE
STIM activating enhancer
decreases expression
ISO
Hypochlorous Acid results in decreased expression of STIMATE mRNA
CTD
PMID:19376150
NCBI chr 3:52,836,733...52,897,548
Ensembl chr 3:52,836,219...52,897,548
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STXBP2
syntaxin binding protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of STXBP2 mRNA
CTD
PMID:19376150
NCBI chr19:7,629,793...7,647,873
Ensembl chr19:7,636,772...7,647,873
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TAOK1
TAO kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TAOK1 mRNA
CTD
PMID:19376150
NCBI chr17:29,390,363...29,551,903
Ensembl chr17:29,390,363...29,551,903
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TBC1D23
TBC1 domain family member 23
increases expression
ISO
Hypochlorous Acid results in increased expression of TBC1D23 mRNA
CTD
PMID:19376150
NCBI chr 3:100,260,992...100,325,238
Ensembl chr 3:100,260,992...100,325,251
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TBCD
tubulin folding cofactor D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBCD mRNA
CTD
PMID:19376150
NCBI chr17:82,752,065...82,945,914
Ensembl chr17:82,752,042...82,945,914
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TBCEL
tubulin folding cofactor E like
increases expression
ISO
Hypochlorous Acid results in increased expression of TBCEL mRNA
CTD
PMID:19376150
NCBI chr11:121,024,102...121,090,776
Ensembl chr11:121,024,072...121,090,776
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TBRG4
transforming growth factor beta regulator 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBRG4 mRNA
CTD
PMID:19376150
NCBI chr 7:45,100,100...45,111,697
Ensembl chr 7:45,100,100...45,112,047
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TFRC
transferrin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of TFRC mRNA
CTD
PMID:19376150
NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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TIFA
TRAF interacting protein with forkhead associated domain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIFA mRNA
CTD
PMID:19376150
NCBI chr 4:112,274,537...112,285,904
Ensembl chr 4:112,272,968...112,285,955
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TIMM44
translocase of inner mitochondrial membrane 44
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIMM44 mRNA
CTD
PMID:19376150
NCBI chr19:7,926,718...7,943,666
Ensembl chr19:7,926,718...7,943,667
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TJP3
tight junction protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TJP3 mRNA
CTD
PMID:19376150
NCBI chr19:3,708,384...3,750,813
Ensembl chr19:3,708,362...3,750,813
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TMED2
transmembrane p24 trafficking protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TMED2 mRNA
CTD
PMID:19376150
NCBI chr12:123,584,552...123,598,582
Ensembl chr12:123,584,533...123,598,582
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TMEM128
transmembrane protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM128 mRNA
CTD
PMID:19376150
NCBI chr 4:4,235,542...4,248,223
Ensembl chr 4:4,235,542...4,248,223
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TMEM33
transmembrane protein 33
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM33 mRNA
CTD
PMID:19376150
NCBI chr 4:41,935,137...41,960,803
Ensembl chr 4:41,935,129...41,960,803
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TNRC6A
trinucleotide repeat containing adaptor 6A
increases expression
ISO
Hypochlorous Acid results in increased expression of TNRC6A mRNA
CTD
PMID:19376150
NCBI chr16:24,610,205...24,826,218
Ensembl chr16:24,610,209...24,827,632
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TOPBP1
DNA topoisomerase II binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TOPBP1 mRNA
CTD
PMID:19376150
NCBI chr 3:133,600,238...133,661,941
Ensembl chr 3:133,598,175...133,662,380
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TP53I11
tumor protein p53 inducible protein 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRP53I11 mRNA
CTD
PMID:19376150
NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306
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TPP2
tripeptidyl peptidase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TPP2 mRNA
CTD
PMID:19376150
NCBI chr13:102,596,986...102,679,958
Ensembl chr13:102,596,958...102,679,958
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TRAP1
TNF receptor associated protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRAP1 mRNA
CTD
PMID:19376150
NCBI chr16:3,658,037...3,717,524
Ensembl chr16:3,651,639...3,717,553
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TREML4
triggering receptor expressed on myeloid cells like 4
increases expression
ISO
Hypochlorous Acid results in increased expression of TREML4 mRNA
CTD
PMID:19376150
NCBI chr 6:41,228,349...41,238,882
Ensembl chr 6:41,228,339...41,238,882
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TRIM27
tripartite motif containing 27
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRIM27 mRNA
CTD
PMID:19376150
NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988
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TRPT1
tRNA phosphotransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRPT1 mRNA
CTD
PMID:19376150
NCBI chr11:64,223,799...64,226,257
Ensembl chr11:64,223,799...64,226,254
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TTC1
tetratricopeptide repeat domain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TTC1 mRNA
CTD
PMID:19376150
NCBI chr 5:160,009,139...160,065,543
Ensembl chr 5:160,009,113...160,065,543
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TTLL3
tubulin tyrosine ligase like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TTLL3 mRNA
CTD
PMID:19376150
NCBI chr 3:9,809,727...9,836,365
Ensembl chr 3:9,808,086...9,855,138
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TXNDC9
thioredoxin domain containing 9
increases expression
ISO
Hypochlorous Acid results in increased expression of TXNDC9 mRNA
CTD
PMID:19376150
NCBI chr 2:99,306,184...99,336,333
Ensembl chr 2:99,318,982...99,340,702
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TXNRD1
thioredoxin reductase 1
increases expression
EXP ISO
Hypochlorous Acid results in increased expression of TXNRD1 mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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UBE2D3
ubiquitin conjugating enzyme E2 D3
increases expression
ISO
Hypochlorous Acid results in increased expression of UBE2D3 mRNA
CTD
PMID:19376150
NCBI chr 4:102,794,383...102,868,895
Ensembl chr 4:102,794,383...102,868,896
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UGCG
UDP-glucose ceramide glucosyltransferase
increases expression
ISO
Hypochlorous Acid results in increased expression of UGCG mRNA
CTD
PMID:19376150
NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369
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UNC119
unc-119 lipid binding chaperone
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC119 mRNA
CTD
PMID:19376150
NCBI chr17:28,546,707...28,552,628
Ensembl chr17:28,546,708...28,552,631
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UNC93B1
unc-93 homolog B1, TLR signaling regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC93B1 mRNA
CTD
PMID:19376150
NCBI chr11:67,991,100...68,004,097
Ensembl chr11:67,991,100...68,004,982
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USO1
USO1 vesicle transport factor
increases expression
ISO
Hypochlorous Acid results in increased expression of USO1 mRNA
CTD
PMID:19376150
NCBI chr 4:75,724,577...75,814,286
Ensembl chr 4:75,724,577...75,814,286
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USP12
ubiquitin specific peptidase 12
increases expression
ISO
Hypochlorous Acid results in increased expression of USP12 mRNA
CTD
PMID:19376150
NCBI chr13:27,066,156...27,171,811
Ensembl chr13:27,066,156...27,171,811
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USP15
ubiquitin specific peptidase 15
increases expression
ISO
Hypochlorous Acid results in increased expression of USP15 mRNA
CTD
PMID:19376150
NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
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USP16
ubiquitin specific peptidase 16
increases expression
ISO
Hypochlorous Acid results in increased expression of USP16 mRNA
CTD
PMID:19376150
NCBI chr21:29,024,668...29,054,488
Ensembl chr21:29,024,629...29,054,488
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USP2
ubiquitin specific peptidase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of USP2 mRNA
CTD
PMID:19376150
NCBI chr11:119,355,215...119,381,690
Ensembl chr11:119,355,215...119,381,711
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VAMP2
vesicle associated membrane protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VAMP2 mRNA
CTD
PMID:19376150
NCBI chr17:8,159,147...8,162,948
Ensembl chr17:8,159,149...8,163,546
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VARS2
valyl-tRNA synthetase 2, mitochondrial
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VARS2 mRNA
CTD
PMID:19376150
NCBI chr 6:30,914,238...30,926,459
Ensembl chr 6:30,914,205...30,926,459
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VMP1
vacuole membrane protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of VMP1 mRNA
CTD
PMID:19376150
NCBI chr17:59,707,654...59,842,255
Ensembl chr17:59,707,192...59,842,255
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VPS13D
vacuolar protein sorting 13 homolog D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS13D mRNA
CTD
PMID:19376150
NCBI chr 1:12,230,030...12,512,047
Ensembl chr 1:12,230,030...12,512,047
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VPS16
VPS16 core subunit of CORVET and HOPS complexes
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS16 mRNA
CTD
PMID:19376150
NCBI chr20:2,840,745...2,866,732
Ensembl chr20:2,840,703...2,866,732
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VPS35
VPS35 retromer complex component
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS35 mRNA
CTD
PMID:19376150
NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518
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VPS54
VPS54 subunit of GARP complex
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS54 mRNA
CTD
PMID:19376150
NCBI chr 2:63,892,150...64,019,428
Ensembl chr 2:63,892,146...64,019,428
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WBP1
WW domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WBP1 mRNA
CTD
PMID:19376150
NCBI chr 2:74,458,438...74,460,881
Ensembl chr 2:74,458,400...74,460,891
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WDR62
WD repeat domain 62
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WDR62 mRNA
CTD
PMID:19376150
NCBI chr19:36,054,897...36,111,145
Ensembl chr19:36,054,649...36,105,108
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YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
increases expression
ISO
Hypochlorous Acid results in increased expression of YWHAZ mRNA
CTD
PMID:19376150
NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388
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ZBTB47
zinc finger and BTB domain containing 47
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZBTB47 mRNA
CTD
PMID:19376150
NCBI chr 3:42,652,931...42,667,580
Ensembl chr 3:42,653,697...42,667,580
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ZC3H15
zinc finger CCCH-type containing 15
increases expression
ISO
Hypochlorous Acid results in increased expression of ZC3H15 mRNA
CTD
PMID:19376150
NCBI chr 2:186,486,260...186,509,361
Ensembl chr 2:186,486,253...186,511,929
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ZDHHC14
zinc finger DHHC-type palmitoyltransferase 14
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZDHHC14 mRNA
CTD
PMID:19376150
NCBI chr 6:157,381,190...157,678,157
Ensembl chr 6:157,381,133...157,678,157
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ZFPM1
zinc finger protein, FOG family member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFPM1 mRNA
CTD
PMID:19376150
NCBI chr16:88,451,769...88,537,031
Ensembl chr16:88,453,280...88,537,031
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ZMYM3
zinc finger MYM-type containing 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZMYM3 mRNA
CTD
PMID:19376150
NCBI chr X:71,239,624...71,255,290
Ensembl chr X:71,239,624...71,255,146
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ZNF24
zinc finger protein 24
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP24 mRNA
CTD
PMID:19376150
NCBI chr18:35,332,227...35,344,420
Ensembl chr18:35,332,227...35,345,482
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ZNF316
zinc finger protein 316
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP316 mRNA
CTD
PMID:19376150
NCBI chr 7:6,637,318...6,658,279
Ensembl chr 7:6,637,318...6,658,279
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ZNF414
zinc finger protein 414
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP414 mRNA
CTD
PMID:19376150
NCBI chr19:8,509,678...8,514,167
Ensembl chr19:8,509,678...8,514,167
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ZNF638
zinc finger protein 638
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP638 mRNA
CTD
PMID:19376150
NCBI chr 2:71,331,782...71,435,061
Ensembl chr 2:71,276,561...71,435,069
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ZNF652
zinc finger protein 652
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP652 mRNA
CTD
PMID:19376150
NCBI chr17:49,288,117...49,362,473
Ensembl chr17:49,289,206...49,362,473
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ZWINT
ZW10 interacting kinetochore protein
increases expression
ISO
Hypochlorous Acid results in increased expression of ZWINT mRNA
CTD
PMID:19376150
NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273
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