CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: halogen oxoacid
Accession: CHEBI:33425
browse the term
Synonyms: related_synonym: halogen oxoacids
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Car1
carbonic anhydrase 1
decreases activity
ISO
chloric acid results in decreased activity of CA1 protein
CTD
PMID:15664814
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
chloric acid results in decreased activity of CA2 protein
CTD
PMID:15664814
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car4
carbonic anhydrase 4
decreases activity
ISO
chloric acid results in decreased activity of CA4 protein
CTD
PMID:15664814
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Car5a
carbonic anhydrase 5A
decreases activity
ISO
chloric acid results in decreased activity of CA5A protein
CTD
PMID:15664814
NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
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Car9
carbonic anhydrase 9
decreases activity
ISO
chloric acid results in decreased activity of CA9 protein
CTD
PMID:15664814
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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Cat
catalase
decreases activity
ISO
chloric acid results in decreased activity of CAT protein
CTD
PMID:21569832
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Gsr
glutathione-disulfide reductase
decreases activity
ISO
chloric acid results in decreased activity of GSR protein
CTD
PMID:21569832
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ABCC1 mRNA
CTD
PMID:19376150
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Abcd1
ATP binding cassette subfamily D member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABCD1 mRNA
CTD
PMID:19376150
NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115
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Abhd16a
abhydrolase domain containing 16A, phospholipase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ABHD16A mRNA
CTD
PMID:19376150
NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927
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Acads
acyl-CoA dehydrogenase short chain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACADS mRNA
CTD
PMID:19376150
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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Acbd4
acyl-CoA binding domain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ACBD4 mRNA
CTD
PMID:19376150
NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500
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Ache
acetylcholinesterase
multiple interactions decreases activity
ISO
[Hypochlorous Acid co-treated with Sodium Nitrite] results in decreased activity of ACHE protein; Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of ACHE protein]
CTD
PMID:12414318 PMID:36924976
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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Adrm1
ADRM1 26S proteasome ubiquitin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of ADRM1 mRNA
CTD
PMID:19376150
NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195
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Afp
alpha-fetoprotein
increases expression
ISO
Hypochlorous Acid results in increased expression of AFP mRNA
CTD
PMID:19376150
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agrn
agrin
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AGRN mRNA
CTD
PMID:19376150
NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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Akr1a1
aldo-keto reductase family 1 member A1
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1A1 mRNA
CTD
PMID:19376150
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Akr1b1
aldo-keto reductase family 1 member B1
increases expression
ISO
Hypochlorous Acid results in increased expression of AKR1B1 mRNA
CTD
PMID:19376150
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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Akr7a2
aldo-keto reductase family 7, member A2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AKR7A5 mRNA
CTD
PMID:19376150
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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Aldh1a3
aldehyde dehydrogenase 1 family, member A3
increases expression
ISO
Hypochlorous Acid results in increased expression of ALDH1A3 mRNA
CTD
PMID:18156441
NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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Amotl1
angiomotin-like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AMOTL1 mRNA
CTD
PMID:19376150
NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573
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Ampd1
adenosine monophosphate deaminase 1
increases activity multiple interactions
ISO
Hypochlorous Acid results in increased activity of AMPD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of AMPD1 protein]
CTD
PMID:36924976
NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
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Angel2
angel homolog 2
increases expression
ISO
Hypochlorous Acid results in increased expression of ANGEL2 mRNA
CTD
PMID:19376150
NCBI chr13:102,509,111...102,529,501
Ensembl chr13:102,510,589...102,529,493
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Ankib1
ankyrin repeat and IBR domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ANKIB1 mRNA
CTD
PMID:19376150
NCBI chr 4:30,333,678...30,457,781
Ensembl chr 4:30,333,677...30,457,781
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Ankrd11
ankyrin repeat domain containing 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD11 mRNA
CTD
PMID:19376150
NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962
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Ankrd13d
ankyrin repeat domain 13D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ANKRD13D mRNA
CTD
PMID:19376150
NCBI chr 1:201,565,712...201,577,987
Ensembl chr 1:201,565,712...201,577,933
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Ap1g2
adaptor related protein complex 1 subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP1G2 mRNA
CTD
PMID:19376150
NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004
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Ap3s2
adaptor related protein complex 3 subunit sigma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of AP3S2 mRNA
CTD
PMID:19376150
NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322
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Apeh
acylaminoacyl-peptide hydrolase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of APEH mRNA
CTD
PMID:19376150
NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
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Apex1
apurinic/apyrimidinic endodeoxyribonuclease 1
multiple interactions increases activity increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein] Hypochlorous Acid results in increased activity of APEX1 protein
CTD
PMID:12231548
NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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Api5
apoptosis inhibitor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of API5 mRNA
CTD
PMID:19376150
NCBI chr 3:80,378,096...80,403,259
Ensembl chr 3:80,378,096...80,403,264
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Apoa1
apolipoprotein A1
multiple interactions
ISO
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein; Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]
CTD
PMID:33861588
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Appbp2
amyloid beta precursor protein binding protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of APPBP2 mRNA
CTD
PMID:19376150
NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
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Arcn1
archain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARCN1 mRNA
CTD
PMID:19376150
NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
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Arhgap24
Rho GTPase activating protein 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGAP24 mRNA
CTD
PMID:19376150
NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823
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Arhgef1
Rho guanine nucleotide exchange factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARHGEF1 mRNA
CTD
PMID:19376150
NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953
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Arih1
ariadne RBR E3 ubiquitin protein ligase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ARIH1 mRNA
CTD
PMID:19376150
NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
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Arl2
ADP-ribosylation factor like GTPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ARL2 mRNA
CTD
PMID:19376150
NCBI chr 1:203,434,129...203,446,156
Ensembl chr 1:203,434,129...203,446,119
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Atxn3
ataxin 3
increases expression
ISO
Hypochlorous Acid results in increased expression of ATXN3 mRNA
CTD
PMID:19376150
NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
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B3gat3
beta-1,3-glucuronyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of B3GAT3 mRNA
CTD
PMID:19376150
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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Bace1
beta-secretase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BACE1 mRNA
CTD
PMID:19376150
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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Bckdk
branched chain ketoacid dehydrogenase kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BCKDK mRNA
CTD
PMID:19376150
NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
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Bclaf1
BCL2-associated transcription factor 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BCLAF1 mRNA
CTD
PMID:19376150
NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
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Bhlhe40
basic helix-loop-helix family, member e40
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BHLHE40 mRNA
CTD
PMID:19376150
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Blvrb
biliverdin reductase B
increases expression
ISO
Hypochlorous Acid results in increased expression of BLVRB mRNA
CTD
PMID:19376150
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Brd4
bromodomain containing 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD4 mRNA
CTD
PMID:19376150
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
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Brd8
bromodomain containing 8
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRD8 mRNA
CTD
PMID:19376150
NCBI chr18:26,204,892...26,229,999
Ensembl chr18:26,181,732...26,229,884
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Bri3
brain protein I3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRI3 mRNA
CTD
PMID:19376150
NCBI chr12:10,341,007...10,364,655
Ensembl chr12:10,341,011...10,364,735
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Brms1
BRMS1, transcriptional repressor and anoikis regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BRMS1 mRNA
CTD
PMID:19376150
NCBI chr 1:202,345,766...202,355,028
Ensembl chr 1:202,345,704...202,355,028
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Btbd2
BTB domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of BTBD2 mRNA
CTD
PMID:19376150
NCBI chr 7:9,058,609...9,075,341
Ensembl chr 7:9,060,788...9,075,344
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Bzw1
basic leucine zipper and W2 domains 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BZW1 mRNA
CTD
PMID:19376150
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
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Cab39
calcium binding protein 39
increases expression
ISO
Hypochlorous Acid results in increased expression of CAB39 mRNA
CTD
PMID:19376150
NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544
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Camk1d
calcium/calmodulin-dependent protein kinase ID
increases expression
ISO
Hypochlorous Acid results in increased expression of CAMK1D mRNA
CTD
PMID:19376150
NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556
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Canx
calnexin
increases expression
ISO
Hypochlorous Acid results in increased expression of CANX mRNA
CTD
PMID:19376150
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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Capn5
calpain 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAPN5 mRNA
CTD
PMID:19376150
NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923
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Car12
carbonic anhydrase 12
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CAR12 mRNA
CTD
PMID:19376150
NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
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Cat
catalase
multiple interactions increases expression increases activity
ISO
CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased expression of CAT mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of CAT protein]
CTD
PMID:17980396 PMID:19376150 PMID:36924976
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccnd3
cyclin D3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CCND3 mRNA
CTD
PMID:19376150
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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Cd47
Cd47 molecule
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CD47 mRNA
CTD
PMID:19376150
NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
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Cdc42
cell division cycle 42
increases expression
ISO
Hypochlorous Acid results in increased expression of CDC42 mRNA
CTD
PMID:19376150
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdca7l
cell division cycle associated 7 like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDCA7L mRNA
CTD
PMID:19376150
NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888
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Cdk5rap3
CDK5 regulatory subunit associated protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK5RAP3 mRNA
CTD
PMID:19376150
NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
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Cdk6
cyclin-dependent kinase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDK6 mRNA
CTD
PMID:19376150
NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
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Cdk7
cyclin-dependent kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of CDK7 mRNA
CTD
PMID:19376150
NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383
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Cds1
CDP-diacylglycerol synthase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CDS1 mRNA
CTD
PMID:19376150
NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681
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Cds2
CDP-diacylglycerol synthase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of CDS2 mRNA
CTD
PMID:19376150
NCBI chr 3:119,514,963...119,553,555
Ensembl chr 3:119,515,000...119,553,541
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Cep43
centrosomal protein 43
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CEP43 mRNA
CTD
PMID:19376150
NCBI chr 1:52,533,418...52,564,025
Ensembl chr 1:52,533,428...52,563,923
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Cep76
centrosomal protein 76
increases expression
ISO
Hypochlorous Acid results in increased expression of CEP76 mRNA
CTD
PMID:19376150
NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504
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Cerk
ceramide kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CERK mRNA
CTD
PMID:19376150
NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759
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Chd3
chromodomain helicase DNA binding protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD3 mRNA
CTD
PMID:19376150
NCBI chr10:54,063,629...54,090,030
Ensembl chr10:54,063,629...54,090,047
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Chd4
chromodomain helicase DNA binding protein 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHD4 mRNA
CTD
PMID:19376150
NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541
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Chit1
chitinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CHIT1 mRNA
CTD
PMID:19376150
NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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Chordc1
cysteine and histidine rich domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CHORDC1 mRNA
CTD
PMID:19376150
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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Clec4d
C-type lectin domain family 4, member D
increases expression
ISO
Hypochlorous Acid results in increased expression of CLEC4D mRNA
CTD
PMID:19376150
NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848
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Cln6
CLN6, transmembrane ER protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLN6 mRNA
CTD
PMID:19376150
NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360
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Clta
clathrin, light chain A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CLTA mRNA
CTD
PMID:19376150
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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Coro1a
coronin 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CORO1A mRNA
CTD
PMID:19376150
NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
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Ctdsp1
CTD small phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTDSP1 mRNA
CTD
PMID:19376150
NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297
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Ctnnbip1
catenin, beta-interacting protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNNBIP1 mRNA
CTD
PMID:19376150
NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
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Ctns
cystinosin, lysosomal cystine transporter
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTNS mRNA
CTD
PMID:19376150
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Ctsb
cathepsin B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of CTSB mRNA
CTD
PMID:19376150
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Cul5
cullin 5
increases expression
ISO
Hypochlorous Acid results in increased expression of CUL5 mRNA
CTD
PMID:19376150
NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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Cyp20a1
cytochrome P450, family 20, subfamily a, polypeptide 1
increases expression
ISO
Hypochlorous Acid results in increased expression of CYP20A1 mRNA
CTD
PMID:19376150
NCBI chr 9:61,755,804...61,805,123
Ensembl chr 9:61,755,790...61,805,123
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Dab2
DAB adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DAB2 mRNA
CTD
PMID:19376150
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
Hypochlorous Acid results in increased expression of DDIT3 mRNA
CTD
PMID:19376150
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddx10
DEAD-box helicase 10
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX10 mRNA
CTD
PMID:19376150
NCBI chr 8:53,488,656...53,643,373
Ensembl chr 8:53,488,656...53,643,373
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Ddx3x
DEAD-box helicase 3, X-linked
increases expression
ISO
Hypochlorous Acid results in increased expression of DDX3X mRNA
CTD
PMID:19376150
NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
G
Dennd1a
DENN domain containing 1A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DENND1A mRNA
CTD
PMID:19376150
NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062
G
Dhx33
DEAH-box helicase 33
increases expression
ISO
Hypochlorous Acid results in increased expression of DHX33 mRNA
CTD
PMID:19376150
NCBI chr10:55,708,102...55,724,618
Ensembl chr10:55,705,756...55,724,567
G
Dlst
dihydrolipoamide S-succinyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DLST mRNA
CTD
PMID:19376150
NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
G
Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNAJA2 mRNA
CTD
PMID:19376150
NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
G
Dnmt1
DNA methyltransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DNMT1 mRNA
CTD
PMID:19376150
NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
G
Dnmt3l
DNA methyltransferase 3 like
increases expression
ISO
Hypochlorous Acid results in increased expression of DNMT3L mRNA
CTD
PMID:19376150
NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516
G
Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DNTTIP2 mRNA
CTD
PMID:19376150
NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581
G
Dr1
down-regulator of transcription 1
increases expression
ISO
Hypochlorous Acid results in increased expression of DR1 mRNA
CTD
PMID:19376150
NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638
G
Dtnb
dystrobrevin, beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTNB mRNA
CTD
PMID:19376150
NCBI chr 6:26,566,418...26,763,467
Ensembl chr 6:26,566,925...26,766,335
G
Dtwd2
DTW domain containing 2
increases expression
ISO
Hypochlorous Acid results in increased expression of DTWD2 mRNA
CTD
PMID:19376150
NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832
G
Dtx3
deltex E3 ubiquitin ligase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of DTX3 mRNA
CTD
PMID:19376150
NCBI chr 7:63,013,769...63,018,431
Ensembl chr 7:63,013,371...63,018,522
G
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EEFSEC mRNA
CTD
PMID:19376150
NCBI chr 4:120,719,616...120,915,779
Ensembl chr 4:120,707,133...120,915,779
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein
CTD
PMID:18156441
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ehmt2
euchromatic histone lysine methyltransferase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EHMT2 mRNA
CTD
PMID:19376150
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
G
Eif5
eukaryotic translation initiation factor 5
increases expression
ISO
Hypochlorous Acid results in increased expression of EIF5 mRNA
CTD
PMID:19376150
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
G
Eloa
elongin A
increases expression
ISO
Hypochlorous Acid results in increased expression of ELOA mRNA
CTD
PMID:19376150
NCBI chr 5:148,231,600...148,246,760
Ensembl chr 5:148,231,596...148,246,765
G
Eri3
ERI1 exoribonuclease family member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERI3 mRNA
CTD
PMID:19376150
NCBI chr 5:131,016,146...131,143,347
Ensembl chr 5:131,016,126...131,143,329
G
Erp29
endoplasmic reticulum protein 29
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ERP29 mRNA
CTD
PMID:19376150
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
G
Esco1
establishment of sister chromatid cohesion N-acetyltransferase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ESCO1 mRNA
CTD
PMID:19376150
NCBI chr18:1,630,560...1,686,803
Ensembl chr18:1,631,954...1,686,942
G
Esd
esterase D
increases expression
ISO
Hypochlorous Acid results in increased expression of ESD mRNA
CTD
PMID:19376150
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
G
Exosc5
exosome component 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of EXOSC5 mRNA
CTD
PMID:19376150
NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265
G
Fance
FA complementation group E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FANCE mRNA
CTD
PMID:19376150
NCBI chr20:6,369,416...6,386,631
Ensembl chr20:6,375,573...6,386,631
G
Fastk
Fas-activated serine/threonine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FASTK mRNA
CTD
PMID:19376150
NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430
G
Fbxl3
F-box and leucine-rich repeat protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of FBXL3 mRNA
CTD
PMID:19376150
NCBI chr15:79,906,795...79,926,678
Ensembl chr15:79,906,795...79,927,867
G
Fbxw5
F-box and WD repeat domain containing 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW5 mRNA
CTD
PMID:19376150
NCBI chr 3:8,322,543...8,327,092
Ensembl chr 3:8,322,543...8,327,092
G
Fbxw7
F-box and WD repeat domain containing 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FBXW7 mRNA
CTD
PMID:19376150
NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941
G
Fgr
FGR proto-oncogene, Src family tyrosine kinase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FGR mRNA
CTD
PMID:19376150
NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
G
Fktn
fukutin
increases expression
ISO
Hypochlorous Acid results in increased expression of FKTN mRNA
CTD
PMID:19376150
NCBI chr 5:68,339,803...68,396,412
Ensembl chr 5:68,340,028...68,396,409
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of FOS mRNA; Hypochlorous Acid results in increased expression of FOS protein
CTD
PMID:19376150
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxred1
FAD-dependent oxidoreductase domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of FOXRED1 mRNA
CTD
PMID:19376150
NCBI chr 8:33,551,010...33,560,227
Ensembl chr 8:33,551,013...33,560,192
G
Ftl1
ferritin light chain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of FTL1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions decreases activity
ISO
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of G6PD protein]
CTD
PMID:36924976
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45A mRNA
CTD
PMID:19376150
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45b
growth arrest and DNA-damage-inducible, beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45B mRNA
CTD
PMID:19376150
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of GADD45G mRNA
CTD
PMID:19376150
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
G
Galk1
galactokinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GALK1 mRNA
CTD
PMID:19376150
NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
G
Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions increases expression affects expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA] Hypochlorous Acid affects the expression of GCLC mRNA
CTD
PMID:17980396 PMID:18648578
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of GCLM mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gmfb
glia maturation factor, beta
increases expression
ISO
Hypochlorous Acid results in increased expression of GMFB mRNA
CTD
PMID:19376150
NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331
G
Gnai3
G protein subunit alpha i3
increases expression
ISO
Hypochlorous Acid results in increased expression of GNAI3 mRNA
CTD
PMID:19376150
NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
G
Gnb2
G protein subunit beta 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GNB2 mRNA
CTD
PMID:19376150
NCBI chr12:19,159,002...19,164,021
Ensembl chr12:19,158,973...19,164,019
G
Gopc
golgi associated PDZ and coiled-coil motif containing
increases expression
ISO
Hypochlorous Acid results in increased expression of GOPC mRNA
CTD
PMID:19376150
NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903
G
Gpbp1
GC-rich promoter binding protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of GPBP1 mRNA
CTD
PMID:19376150
NCBI chr 2:43,023,504...43,091,146
Ensembl chr 2:43,023,504...43,090,907
G
Gpx1
glutathione peroxidase 1
decreases expression multiple interactions increases activity
ISO
Hypochlorous Acid results in decreased expression of GPX1 mRNA Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of GPX1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx4
glutathione peroxidase 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GPX4 mRNA
CTD
PMID:19376150
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grn
granulin precursor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of GRN mRNA
CTD
PMID:19376150
NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
G
Gsr
glutathione-disulfide reductase
increases expression decreases activity multiple interactions
ISO
Hypochlorous Acid results in increased expression of GSR mRNA Hypochlorous Acid results in decreased activity of GSR protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of GSR protein]
CTD
PMID:17980396 PMID:36924976
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gss
glutathione synthetase
increases expression
ISO
Hypochlorous Acid results in increased expression of GSS mRNA
CTD
PMID:17980396
NCBI chr 3:144,047,849...144,078,197
Ensembl chr 3:144,047,850...144,078,198
G
H2bc18
H2B clustered histone 18
increases expression
ISO
Hypochlorous Acid results in increased expression of H2BC18 mRNA
CTD
PMID:19376150
NCBI chr 2:183,838,331...183,842,769
Ensembl chr 2:183,838,334...183,841,529
G
Haghl
hydroxyacylglutathione hydrolase-like
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAGHL mRNA
CTD
PMID:19376150
NCBI chr10:14,804,957...14,809,495
Ensembl chr10:14,804,997...14,807,665
G
Haus4
HAUS augmin-like complex, subunit 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HAUS4 mRNA
CTD
PMID:19376150
NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938
G
Hdac10
histone deacetylase 10
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC10 mRNA
CTD
PMID:19376150
NCBI chr 7:120,199,126...120,205,850
Ensembl chr 7:120,199,129...120,204,228
G
Hdac5
histone deacetylase 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC5 mRNA
CTD
PMID:19376150
NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
G
Hdac6
histone deacetylase 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HDAC6 mRNA
CTD
PMID:19376150
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
G
Hexd
hexosaminidase D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HEXD mRNA
CTD
PMID:19376150
NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799
G
Hipk2
homeodomain interacting protein kinase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK2 mRNA
CTD
PMID:19376150
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
G
Hipk3
homeodomain interacting protein kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of HIPK3 mRNA
CTD
PMID:19376150
NCBI chr 3:90,796,980...90,866,701
Ensembl chr 3:90,800,296...90,867,759
G
Hk1
hexokinase 1
multiple interactions decreases activity
ISO
Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of HK1 protein]
CTD
PMID:36924976
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
G
Hmga2
high mobility group AT-hook 2
increases expression
ISO
Hypochlorous Acid results in increased expression of HMGA2 mRNA
CTD
PMID:19376150
NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
G
Hmox1
heme oxygenase 1
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA] Hypochlorous Acid results in increased expression of HMOX1 mRNA; Hypochlorous Acid results in increased expression of HMOX1 protein [Quercetin co-treated with Hypochlorous Acid] results in increased expression of HMOX1 protein
CTD
PMID:17980396 PMID:18156441 PMID:19376150 PMID:24017971
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hpcal1
hippocalcin-like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPCAL1 mRNA
CTD
PMID:19376150
NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687
G
Hprt1
hypoxanthine phosphoribosyltransferase 1
increases mutagenesis
ISO
Hypochlorous Acid results in increased mutagenesis of HPRT1 gene
CTD
PMID:19892774
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
G
Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of HPS1 mRNA
CTD
PMID:19376150
NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of HSP90AA1 mRNA
CTD
PMID:19376150
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
G
Hspa13
heat shock protein family A (Hsp70) member 13
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA13 mRNA
CTD
PMID:19376150
NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]
CTD
PMID:12231548
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
G
Hspa1b
heat shock protein family A (Hsp70) member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of HSPA1B mRNA
CTD
PMID:19376150
NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 Ensembl chr20:3,856,006...3,873,240
G
Ifng
interferon gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IFNG mRNA
CTD
PMID:19376150
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Ikbkg
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
increases expression
ISO
Hypochlorous Acid results in increased expression of IKBKG mRNA
CTD
PMID:19376150
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
G
Il10
interleukin 10
increases expression
ISO
Hypochlorous Acid results in increased expression of IL10 mRNA
CTD
PMID:19376150
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il1b
interleukin 1 beta
increases expression
ISO
Hypochlorous Acid results in increased expression of IL1B mRNA
CTD
PMID:19376150
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il6
interleukin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of IL6 mRNA
CTD
PMID:19376150
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ing2
inhibitor of growth family, member 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ING2 mRNA
CTD
PMID:19376150
NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
G
Ints7
integrator complex subunit 7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of INTS7 mRNA
CTD
PMID:19376150
NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592
G
Ints8
integrator complex subunit 8
increases expression
ISO
Hypochlorous Acid results in increased expression of INTS8 mRNA
CTD
PMID:19376150
NCBI chr 5:24,295,542...24,344,642
Ensembl chr 5:24,297,191...24,344,740
G
Itgb5
integrin subunit beta 5
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ITGB5 mRNA
CTD
PMID:19376150
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
G
Jag1
jagged canonical Notch ligand 1
increases expression
ISO
Hypochlorous Acid results in increased expression of JAG1 mRNA
CTD
PMID:19376150
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
G
Jak3
Janus kinase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of JAK3 mRNA
CTD
PMID:19376150
NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
G
Kbtbd8
kelch repeat and BTB domain containing 8
increases expression
ISO
Hypochlorous Acid results in increased expression of KBTBD8 mRNA
CTD
PMID:19376150
NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
G
Keap1
Kelch-like ECH-associated protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KEAP1 mRNA
CTD
PMID:17980396
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
G
Kif1b
kinesin family member 1B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF1B mRNA
CTD
PMID:19376150
NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
G
Kif24
kinesin family member 24
decreases expression
ISO
Hypochlorous Acid results in decreased expression of KIF24 mRNA
CTD
PMID:19376150
NCBI chr 5:56,561,019...56,628,040
Ensembl chr 5:56,561,154...56,628,025
G
Kif3c
kinesin family member 3C
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF3C mRNA
CTD
PMID:19376150
NCBI chr 6:26,367,092...26,406,033
Ensembl chr 6:26,366,531...26,406,130
G
Kif5b
kinesin family member 5B
increases expression
ISO
Hypochlorous Acid results in increased expression of KIF5B mRNA
CTD
PMID:19376150
NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508
G
Kpna1
karyopherin subunit alpha 1
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA1 mRNA
CTD
PMID:19376150
NCBI chr11:64,715,844...64,774,647
Ensembl chr11:64,717,563...64,774,623
G
Kpna4
karyopherin subunit alpha 4
increases expression
ISO
Hypochlorous Acid results in increased expression of KPNA4 mRNA
CTD
PMID:19376150
NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081
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Krr1
KRR1, small subunit processome component homolog
increases expression
ISO
Hypochlorous Acid results in increased expression of KRR1 mRNA
CTD
PMID:19376150
NCBI chr 7:47,475,557...47,486,996
Ensembl chr 7:47,475,557...47,486,985
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Lcat
lecithin cholesterol acyltransferase
multiple interactions
ISO
[Hypochlorous Acid results in increased oxidation of [APOA1 protein binds to Lipids]] which results in decreased activity of LCAT protein
CTD
PMID:33861588
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Ldha
lactate dehydrogenase A
increases activity multiple interactions
ISO
Hypochlorous Acid results in increased activity of LDHA protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of LDHA protein]
CTD
PMID:36924976
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
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Limd2
LIM domain containing 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LIMD2 mRNA
CTD
PMID:19376150
NCBI chr10:91,090,279...91,092,772
Ensembl chr10:91,090,280...91,092,775
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Lmf1
lipase maturation factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LMF1 mRNA
CTD
PMID:19376150
NCBI chr10:14,597,726...14,684,071
Ensembl chr10:14,597,594...14,684,119
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Loxl3
lysyl oxidase-like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LOXL3 mRNA
CTD
PMID:19376150
NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
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Lrp1
LDL receptor related protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of LRP1 mRNA
CTD
PMID:19376150
NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
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Lrrc8d
leucine rich repeat containing 8 VRAC subunit D
increases expression
ISO
Hypochlorous Acid results in increased expression of LRRC8D mRNA
CTD
PMID:19376150
NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877
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Maff
MAF bZIP transcription factor F
increases expression
ISO
Hypochlorous Acid results in increased expression of MAFF mRNA
CTD
PMID:18156441
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
Hypochlorous Acid results in increased expression of MAFG mRNA
CTD
PMID:18156441
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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Man1a2
mannosidase, alpha, class 1A, member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of MAN1A2 mRNA
CTD
PMID:19376150
NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332
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Man1c1
mannosidase, alpha, class 1C, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN1C1 mRNA
CTD
PMID:19376150
NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421
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Man2c1
mannosidase, alpha, class 2C, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAN2C1 mRNA
CTD
PMID:19376150
NCBI chr 8:57,537,879...57,549,691
Ensembl chr 8:57,537,321...57,549,690
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Map3k7
mitogen activated protein kinase kinase kinase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of MAP3K7 mRNA
CTD
PMID:19376150
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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Map4k1
mitogen activated protein kinase kinase kinase kinase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MAP4K1 mRNA
CTD
PMID:19376150
NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD
PMID:18156441
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk10
mitogen activated protein kinase 10
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK10 protein
CTD
PMID:18156441
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD
PMID:18156441
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk6
mitogen-activated protein kinase 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MAPK6 mRNA
CTD
PMID:19376150
NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD
PMID:18156441
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Mapk9
mitogen-activated protein kinase 9
multiple interactions
ISO
Hypochlorous Acid results in increased phosphorylation of and results in increased activity of MAPK9 protein
CTD
PMID:18156441
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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Marchf2
membrane associated ring-CH-type finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MARCHF2 mRNA
CTD
PMID:19376150
NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794
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Me1
malic enzyme 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ME1 mRNA
CTD
PMID:19376150
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Mfap1a
microfibrillar-associated protein 1A
increases expression
ISO
Hypochlorous Acid results in increased expression of MFAP1 mRNA
CTD
PMID:19376150
NCBI chr 3:108,440,163...108,456,744
Ensembl chr 3:108,438,845...108,456,750
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Mfsd13a
major facilitator superfamily domain containing 13A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MFSD13A mRNA
CTD
PMID:19376150
NCBI chr 1:245,216,610...245,236,314
Ensembl chr 1:245,217,067...245,236,767
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Miip
migration and invasion inhibitory protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MIIP mRNA
CTD
PMID:19376150
NCBI chr 5:158,292,510...158,299,533
Ensembl chr 5:158,292,511...158,299,694
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Mob1a
MOB kinase activator 1A
increases expression
ISO
Hypochlorous Acid results in increased expression of MOB1A mRNA
CTD
PMID:19376150
NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561
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Mpo
myeloperoxidase
multiple interactions increases chemical synthesis increases abundance
ISO
4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; 4-aminobenzhydrazide inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [[MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of nimesulide metabolite] which results in increased chemical synthesis of nimesulide metabolite; [Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [ethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [MPO protein co-treated with Hypochlorous Acid] results in increased oxidation of and affects the activity of nimesulide metabolite; [MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid; [Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; [trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; Heparin inhibits the reaction [4-amino-TEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[1,6-diaminohexane binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Cadaverine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Putrescine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[Spermine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; Heparin inhibits the reaction [[trimethylenediamine binds to TEMPO] inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]]; MitoTEMPO inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]; TEMPOL-H inhibits the reaction [MPO protein results in increased chemical synthesis of Hypochlorous Acid]
CTD
PMID:7772042 PMID:20939553 PMID:34085520 PMID:35575633
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mrpl4
mitochondrial ribosomal protein L4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MRPL4 mRNA
CTD
PMID:19376150
NCBI chr 8:19,539,593...19,545,608
Ensembl chr 8:19,539,593...19,545,608
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Msrb1
methionine sulfoxide reductase B1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MSRB1 mRNA
CTD
PMID:19376150
NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609
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Mta1
metastasis associated 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA1 mRNA
CTD
PMID:19376150
NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
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Mta3
metastasis associated 1 family, member 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTA3 mRNA
CTD
PMID:19376150
NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883
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Mtarc2
mitochondrial amidoxime reducing component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MTARC2 mRNA
CTD
PMID:19376150
NCBI chr13:96,362,810...96,397,284
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Mtdh
metadherin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTDH mRNA
CTD
PMID:19376150
NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
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Mtmr6
myotubularin related protein 6
increases expression
ISO
Hypochlorous Acid results in increased expression of MTMR6 mRNA
CTD
PMID:19376150
NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
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Mtpn
myotrophin
increases expression
ISO
Hypochlorous Acid results in increased expression of MTPN mRNA
CTD
PMID:19376150
NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724
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Muc16
mucin 16, cell surface associated
increases expression
ISO
Hypochlorous Acid results in increased expression of MUC16 mRNA
CTD
PMID:19376150
NCBI chr 8:16,164,531...16,323,126
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Mvd
mevalonate diphosphate decarboxylase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MVD mRNA
CTD
PMID:19376150
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Myh9
myosin, heavy chain 9
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYH9 mRNA
CTD
PMID:19376150
NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
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Myo1f
myosin IF
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO1F mRNA
CTD
PMID:19376150
NCBI chr 7:14,363,340...14,413,911
Ensembl chr 7:14,363,350...14,413,911
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Myo9b
myosin IXb
decreases expression
ISO
Hypochlorous Acid results in decreased expression of MYO9B mRNA
CTD
PMID:19376150
NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126
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Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
increases expression
ISO
Hypochlorous Acid results in increased expression of NAA15 mRNA
CTD
PMID:19376150
NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756
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Ncaph2
non-SMC condensin II complex, subunit H2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NCAPH2 mRNA
CTD
PMID:19376150
NCBI chr 7:120,422,926...120,439,942
Ensembl chr 7:120,422,956...120,439,938
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Ndufs2
NADH:ubiquinone oxidoreductase core subunit S2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS2 mRNA
CTD
PMID:19376150
NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
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Ndufs7
NADH:ubiquinone oxidoreductase core subunit S7
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NDUFS7 mRNA
CTD
PMID:19376150
NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
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Nelfe
negative elongation factor complex member E
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELFE mRNA
CTD
PMID:19376150
NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355
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Nell1
neural EGFL like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NELL1 mRNA
CTD
PMID:19376150
NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions increases expression affects response to substance
ISO
Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] NFE2L2 protein affects the susceptibility to Hypochlorous Acid Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; CAT protein modified form inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; S-ethyl glutathione inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA] Hypochlorous Acid results in increased expression of NFE2L2 protein
CTD
PMID:17980396 PMID:18156441
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nol11
nucleolar protein 11
increases expression
ISO
Hypochlorous Acid results in increased expression of NOL11 mRNA
CTD
PMID:19376150
NCBI chr10:92,119,000...92,141,688
Ensembl chr10:92,121,833...92,141,677
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression affects expression
ISO
Hypochlorous Acid results in increased expression of NQO1 mRNA Hypochlorous Acid affects the expression of NQO1 mRNA
CTD
PMID:17980396 PMID:18156441 PMID:18648578 PMID:19376150
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1d1
nuclear receptor subfamily 1, group D, member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of NR1D1 mRNA
CTD
PMID:19376150
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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Nrp1
neuropilin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of NRP1 mRNA
CTD
PMID:19376150
NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
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Nup54
nucleoporin 54
increases expression
ISO
Hypochlorous Acid results in increased expression of NUP54 mRNA
CTD
PMID:19376150
NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028
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Otud4
OTU deubiquitinase 4
increases expression
ISO
Hypochlorous Acid results in increased expression of OTUD4 mRNA
CTD
PMID:19376150
NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815
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P3h3
prolyl 3-hydroxylase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of P3H3 mRNA
CTD
PMID:19376150
NCBI chr 4:157,646,242...157,662,035
Ensembl chr 4:157,646,243...157,662,035
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Pacsin3
protein kinase C and casein kinase substrate in neurons 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PACSIN3 mRNA
CTD
PMID:19376150
NCBI chr 3:77,227,187...77,235,820
Ensembl chr 3:77,222,710...77,235,811
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Pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PAFAH1B2 mRNA
CTD
PMID:19376150
NCBI chr 8:46,260,069...46,312,073
Ensembl chr 8:46,261,064...46,279,833
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Pak1ip1
PAK1 interacting protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PAK1IP1 mRNA
CTD
PMID:19376150
NCBI chr17:23,742,217...23,753,325
Ensembl chr17:23,741,414...23,753,324
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Papola
poly (A) polymerase alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PAPOLA mRNA
CTD
PMID:19376150
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
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Parvb
parvin, beta
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PARVB mRNA
CTD
PMID:19376150
NCBI chr 7:115,360,254...115,445,767
Ensembl chr 7:115,360,261...115,445,766
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Pcdhgc3
protocadherin gamma subfamily C, 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PCDHGC3 mRNA
CTD
PMID:19376150
NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
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Pcgf2
polycomb group ring finger 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PCGF2 mRNA
CTD
PMID:19376150
NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
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Pex6
peroxisomal biogenesis factor 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PEX6 mRNA
CTD
PMID:19376150
NCBI chr 9:14,258,145...14,270,335
Ensembl chr 9:14,258,145...14,270,303
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Pgrmc2
progesterone receptor membrane component 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PGRMC2 mRNA
CTD
PMID:19376150
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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Phka2
phosphorylase kinase regulatory subunit alpha 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKA2 mRNA
CTD
PMID:19376150
NCBI chr X:34,170,959...34,293,498
Ensembl chr X:34,171,323...34,293,466
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Phkg2
phosphorylase kinase catalytic subunit gamma 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHKG2 mRNA
CTD
PMID:19376150
NCBI chr 1:182,184,362...182,197,124
Ensembl chr 1:182,184,650...182,197,124
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Phpt1
phosphohistidine phosphatase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PHPT1 mRNA
CTD
PMID:19376150
NCBI chr 3:8,392,926...8,394,325
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Pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
increases expression
ISO
Hypochlorous Acid results in increased expression of PIK3C2A mRNA
CTD
PMID:19376150
NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PKMYT1 mRNA
CTD
PMID:19376150
NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
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Plcb3
phospholipase C beta 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLCB3 mRNA
CTD
PMID:19376150
NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
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Plxnb2
plexin B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PLXNB2 mRNA
CTD
PMID:19376150
NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330
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Pnkd
PNKD metallo-beta-lactamase domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PNKD mRNA
CTD
PMID:19376150
NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124
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Pold1
DNA polymerase delta 1, catalytic subunit
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLD1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
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Poll
DNA polymerase lambda
decreases expression
ISO
Hypochlorous Acid results in decreased expression of POLL mRNA
CTD
PMID:19376150
NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
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Pon1
paraoxonase 1
decreases activity multiple interactions increases oxidation
ISO
Hypochlorous Acid results in decreased activity of PON1 protein Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]] Hypochlorous Acid results in increased oxidation of PON1 protein
CTD
PMID:14671042 PMID:15104111
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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Ppfia4
PTPRF interacting protein alpha 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPFIA4 mRNA
CTD
PMID:19376150
NCBI chr13:45,753,827...45,802,305
Ensembl chr13:45,753,827...45,802,261
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Ppox
protoporphyrinogen oxidase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPOX mRNA
CTD
PMID:19376150
NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805
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Ppp2r1a
protein phosphatase 2 scaffold subunit A alpha
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PPP2R1A mRNA
CTD
PMID:19376150
NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
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Prdx1
peroxiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PRDX1 mRNA
CTD
PMID:19376150
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx5
peroxiredoxin 5
decreases activity multiple interactions
ISO
Hypochlorous Acid results in decreased activity of PRDX5 protein Curcumin inhibits the reaction [Hypochlorous Acid results in decreased activity of PRDX5 protein]
CTD
PMID:36924976
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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Prkar2b
protein kinase cAMP-dependent type II regulatory subunit beta
increases expression
ISO
Hypochlorous Acid results in increased expression of PRKAR2B mRNA
CTD
PMID:19376150
NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933
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Procr
protein C receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PROCR mRNA
CTD
PMID:19376150
NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
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Psma7
proteasome 20S subunit alpha 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMA7 mRNA
CTD
PMID:19376150
NCBI chr 3:167,137,279...167,143,626
Ensembl chr 3:167,137,263...167,143,672
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Psmb3
proteasome 20S subunit beta 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMB3 mRNA
CTD
PMID:19376150
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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Psmc1
proteasome 26S subunit, ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC1 mRNA
CTD
PMID:19376150
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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Psmc2
proteasome 26S subunit, ATPase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMC2 mRNA
CTD
PMID:19376150
NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185
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Psmd1
proteasome 26S subunit, non-ATPase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD1 mRNA
CTD
PMID:19376150
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd11
proteasome 26S subunit, non-ATPase 11
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD11 mRNA
CTD
PMID:19376150
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
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Psmd5
proteasome 26S subunit, non-ATPase 5
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD5 mRNA
CTD
PMID:19376150
NCBI chr 3:18,133,715...18,151,000
Ensembl chr 3:18,133,717...18,151,029
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Psmd7
proteasome 26S subunit, non-ATPase 7
increases expression
ISO
Hypochlorous Acid results in increased expression of PSMD7 mRNA
CTD
PMID:19376150
NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588
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Ptbp3
polypyrimidine tract binding protein 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTBP3 mRNA
CTD
PMID:19376150
NCBI chr 5:74,313,367...74,399,439
Ensembl chr 5:74,315,101...74,399,791
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Ptges2
prostaglandin E synthase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTGES2 mRNA
CTD
PMID:19376150
NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688
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Ptges3
prostaglandin E synthase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGES3 mRNA
CTD
PMID:19376150
NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
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Ptgir
prostaglandin I2 receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of PTGIR mRNA
CTD
PMID:19376150
NCBI chr 1:77,579,596...77,581,979
Ensembl chr 1:77,579,596...77,581,979
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Ptov1
PTOV1, extended AT-hook containing adaptor protein
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTOV1 mRNA
CTD
PMID:19376150
NCBI chr 1:95,347,065...95,354,514
Ensembl chr 1:95,347,068...95,353,613
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Ptp4a3
protein tyrosine phosphatase 4A3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PTP4A3 mRNA
CTD
PMID:19376150
NCBI chr 7:105,650,640...105,660,921
Ensembl chr 7:105,628,029...105,660,919
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Ptpn12
protein tyrosine phosphatase, non-receptor type 12
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN12 mRNA
CTD
PMID:19376150
NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927
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Ptpn14
protein tyrosine phosphatase, non-receptor type 14
increases expression
ISO
Hypochlorous Acid results in increased expression of PTPN14 mRNA
CTD
PMID:19376150
NCBI chr13:101,268,258...101,420,508
Ensembl chr13:101,268,416...101,414,088
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Pwwp2b
PWWP domain containing 2B
decreases expression
ISO
Hypochlorous Acid results in decreased expression of PWWP2B mRNA
CTD
PMID:19376150
NCBI chr 1:194,040,395...194,059,979
Ensembl chr 1:194,041,341...194,059,958
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Rab10
RAB10, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB10 mRNA
CTD
PMID:19376150
NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193
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Rab18
RAB18, member RAS oncogene family
increases expression
ISO
Hypochlorous Acid results in increased expression of RAB18 mRNA
CTD
PMID:19376150
NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
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Rab22a
RAB22A, member RAS oncogene family
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RAB22A mRNA
CTD
PMID:19376150
NCBI chr 3:162,459,727...162,506,129
Ensembl chr 3:162,459,726...162,506,137
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Rabep1
rabaptin, RAB GTPase binding effector protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RABEP1 mRNA
CTD
PMID:19376150
NCBI chr10:55,566,156...55,667,595
Ensembl chr10:55,566,185...55,665,973
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Ralgdsl1
ral guanine nucleotide dissociation stimulator like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL1 mRNA
CTD
PMID:19376150
NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191
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Ralgdsl2
ral guanine nucleotide dissociation stimulator like 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RGL2 mRNA
CTD
PMID:19376150
NCBI chr20:4,948,495...4,956,774
Ensembl chr20:4,948,497...4,969,911
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Rassf4
Ras association domain family member 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RASSF4 mRNA
CTD
PMID:19376150
NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411
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Rbck1
RANBP2-type and C3HC4-type zinc finger containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RBCK1 mRNA
CTD
PMID:19376150
NCBI chr 3:140,789,079...140,806,017
Ensembl chr 3:140,789,080...140,806,005
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Rbm18
RNA binding motif protein 18
increases expression
ISO
Hypochlorous Acid results in increased expression of RBM18 mRNA
CTD
PMID:19376150
NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178
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Rbx1
ring-box 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RBX1 mRNA
CTD
PMID:19376150
NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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Rdx
radixin
increases expression
ISO
Hypochlorous Acid results in increased expression of RDX mRNA
CTD
PMID:19376150
NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
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Reep6
receptor accessory protein 6
decreases expression
ISO
Hypochlorous Acid results in decreased expression of REEP6 mRNA
CTD
PMID:19376150
NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
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Ric8a
RIC8 guanine nucleotide exchange factor A
increases expression
ISO
Hypochlorous Acid results in increased expression of RIC8A mRNA
CTD
PMID:19376150
NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467
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Riok3
RIO kinase 3
increases expression
ISO
Hypochlorous Acid results in increased expression of RIOK3 mRNA
CTD
PMID:19376150
NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343
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Rnaseh1
ribonuclease H1
increases expression
ISO
Hypochlorous Acid results in increased expression of RNASEH1 mRNA
CTD
PMID:19376150
NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236
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Rnf115
ring finger protein 115
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF115 mRNA
CTD
PMID:19376150
NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823
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Rnf128
ring finger protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF128 mRNA
CTD
PMID:19376150
NCBI chr X:103,183,643...103,298,431
Ensembl chr X:103,183,831...103,298,423
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Rnf157
ring finger protein 157
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF157 mRNA
CTD
PMID:19376150
NCBI chr10:101,571,972...101,639,874
Ensembl chr10:101,566,295...101,639,942
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Rnf183
ring finger protein 183
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF183 mRNA
CTD
PMID:19376150
NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191
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Rnf26
ring finger protein 26
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RNF26 mRNA
CTD
PMID:19376150
NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331
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Rnf4
ring finger protein 4
increases expression
ISO
Hypochlorous Acid results in increased expression of RNF4 mRNA
CTD
PMID:19376150
NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566
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Rock1
Rho-associated coiled-coil containing protein kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of ROCK1 mRNA
CTD
PMID:19376150
NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
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Rpf1
ribosome production factor 1
increases expression
ISO
Hypochlorous Acid results in increased expression of BXDC5 mRNA
CTD
PMID:19376150
NCBI chr 2:235,403,020...235,417,546
Ensembl chr 2:235,403,021...235,417,807
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Rpl35
ribosomal protein L35
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPL35 mRNA
CTD
PMID:19376150
NCBI chr 3:22,753,255...22,756,217
Ensembl chr 3:22,753,253...22,756,243
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Rps6kb2
ribosomal protein S6 kinase B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RPS6KB2 mRNA
CTD
PMID:19376150
NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078
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Rsl1d1
ribosomal L1 domain containing 1
increases expression
ISO
Hypochlorous Acid results in increased expression of RSL1D1 mRNA
CTD
PMID:19376150
NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
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Ruvbl2
RuvB-like AAA ATPase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RUVBL2 mRNA
CTD
PMID:19376150
NCBI chr 1:95,902,014...95,915,247
Ensembl chr 1:95,901,701...95,915,342
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Rwdd2a
RWD domain containing 2A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RWDD2A mRNA
CTD
PMID:19376150
NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300
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Satb2
SATB homeobox 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SATB2 mRNA
CTD
PMID:19376150
NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
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Sbf1
SET binding factor 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SBF1 mRNA
CTD
PMID:19376150
NCBI chr 7:120,358,338...120,385,022
Ensembl chr 7:120,358,338...120,384,902
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Scand1
SCAN domain-containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SCAND1 mRNA
CTD
PMID:19376150
NCBI chr 3:144,818,615...144,819,479
Ensembl chr 3:144,818,611...144,820,025
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Sdc3
syndecan 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SDC3 mRNA
CTD
PMID:19376150
NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480
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Sec63
SEC63 homolog, protein translocation regulator
increases expression
ISO
Hypochlorous Acid results in increased expression of SEC63 mRNA
CTD
PMID:19376150
NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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Selplg
selectin P ligand
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SELPLG mRNA
CTD
PMID:19376150
NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585
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Sema5a
semaphorin 5A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SEMA5A mRNA
CTD
PMID:19376150
NCBI chr 2:83,309,843...83,741,084
Ensembl chr 2:83,309,843...83,741,084
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Sergef
secretion regulating guanine nucleotide exchange factor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SERGEF mRNA
CTD
PMID:19376150
NCBI chr 1:96,949,660...97,152,529
Ensembl chr 1:96,949,661...97,152,496
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Serinc1
serine incorporator 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERINC1 mRNA
CTD
PMID:19376150
NCBI chr20:36,850,062...36,868,999
Ensembl chr20:36,850,076...36,896,691
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Serpinb9
serpin family B member 9
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINB9 mRNA
CTD
PMID:19376150
NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230
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Serpine1
serpin family E member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SERPINE1 mRNA
CTD
PMID:19376150
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Setd6
SET domain containing 6, protein lysine methyltransferase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SETD6 mRNA
CTD
PMID:19376150
NCBI chr19:9,343,309...9,350,477
Ensembl chr19:9,347,458...9,350,453
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Sh2b2
SH2B adaptor protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH2B2 mRNA
CTD
PMID:19376150
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
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Sh3bp1
SH3-domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SH3BP1 mRNA
CTD
PMID:19376150
NCBI chr 7:110,457,626...110,470,201
Ensembl chr 7:110,457,710...110,470,201
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Sigirr
single Ig and TIR domain containing
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIGIRR mRNA
CTD
PMID:19376150
NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269
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Sipa1l1
signal-induced proliferation-associated 1 like 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SIPA1L1 mRNA
CTD
PMID:19376150
NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
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Sla
src-like adaptor
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLA mRNA
CTD
PMID:19376150
NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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Slc20a1
solute carrier family 20 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC20A1 mRNA
CTD
PMID:19376150
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
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Slc23a2
solute carrier family 23 member 2
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC23A2 mRNA
CTD
PMID:19376150
NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc25a1
solute carrier family 25 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A1 mRNA
CTD
PMID:19376150
NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
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Slc25a12
solute carrier family 25 member 12
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC25A12 mRNA
CTD
PMID:19376150
NCBI chr 3:56,097,166...56,191,841
Ensembl chr 3:56,097,269...56,192,100
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Slc25a28
solute carrier family 25 member 28
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A28 mRNA
CTD
PMID:19376150
NCBI chr 1:242,530,877...242,542,140
Ensembl chr 1:242,530,899...242,542,115
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Slc25a39
solute carrier family 25, member 39
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC25A39 mRNA
CTD
PMID:19376150
NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260
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Slc35b2
solute carrier family 35 member B2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35B2 mRNA
CTD
PMID:19376150
NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
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Slc35c2
solute carrier family 35 member C2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SLC35C2 mRNA
CTD
PMID:19376150
NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488
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Slc39a6
solute carrier family 39 member 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC39A6 mRNA
CTD
PMID:19376150
NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
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Slc40a1
solute carrier family 40 member 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC40A1 mRNA
CTD
PMID:19376150
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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Slc50a1
solute carrier family 50 member 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of RAG1AP1 mRNA
CTD
PMID:19376150
NCBI chr 2:174,677,985...174,680,366
Ensembl chr 2:174,677,708...174,680,366
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Hypochlorous Acid results in increased expression of SLC7A11 mRNA
CTD
PMID:19376150
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slk
STE20-like kinase
increases expression
ISO
Hypochlorous Acid results in increased expression of SLK mRNA
CTD
PMID:19376150
NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
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Slmap
sarcolemma associated protein
increases expression
ISO
Hypochlorous Acid results in increased expression of SLMAP mRNA
CTD
PMID:19376150
NCBI chr16:1,667,205...1,785,200
Ensembl chr16:1,667,208...1,785,149
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Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
increases expression
ISO
Hypochlorous Acid results in increased expression of SMARCA5 mRNA
CTD
PMID:19376150
NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
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Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMARCD2 mRNA
CTD
PMID:19376150
NCBI chr10:91,193,752...91,202,817
Ensembl chr10:91,193,752...91,204,341
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Smyd1
SET and MYND domain containing 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SMYD1 mRNA
CTD
PMID:19376150
NCBI chr 4:103,195,330...103,252,989
Ensembl chr 4:103,200,322...103,311,766
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Smyd4
SET and MYND domain containing 4
increases expression
ISO
Hypochlorous Acid results in increased expression of SMYD4 mRNA
CTD
PMID:19376150
NCBI chr10:60,200,067...60,246,387
Ensembl chr10:60,200,114...60,246,387
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Snrpa
small nuclear ribonucleoprotein polypeptide A
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNRPA mRNA
CTD
PMID:19376150
NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
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Snx17
sorting nexin 17
decreases expression
ISO
Hypochlorous Acid results in decreased expression of SNX17 mRNA
CTD
PMID:19376150
NCBI chr 6:25,177,528...25,183,001
Ensembl chr 6:25,177,391...25,183,030
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Snx6
sorting nexin 6
increases expression
ISO
Hypochlorous Acid results in increased expression of SNX6 mRNA
CTD
PMID:19376150
NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911
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Sod1
superoxide dismutase 1
increases expression increases activity multiple interactions
ISO
Hypochlorous Acid results in increased expression of SOD1 protein Hypochlorous Acid results in increased activity of SOD1 protein Curcumin inhibits the reaction [Hypochlorous Acid results in increased activity of SOD1 protein]
CTD
PMID:19376150 PMID:36924976
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sqstm1
sequestosome 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SQSTM1 mRNA
CTD
PMID:19376150
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srxn1
sulfiredoxin 1
increases expression
ISO
Hypochlorous Acid results in increased expression of SRXN1 mRNA
CTD
PMID:19376150
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Ssb
small RNA binding exonuclease protection factor La
increases expression
ISO
Hypochlorous Acid results in increased expression of SSB mRNA
CTD
PMID:19376150
NCBI chr 3:54,616,616...54,626,203
Ensembl chr 3:54,616,619...54,626,203
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St14
ST14 transmembrane serine protease matriptase
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST14 mRNA
CTD
PMID:19376150
NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
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St3gal3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ST3GAL3 mRNA
CTD
PMID:19376150
NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810
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Stxbp2
syntaxin binding protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of STXBP2 mRNA
CTD
PMID:19376150
NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
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Taok1
TAO kinase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TAOK1 mRNA
CTD
PMID:19376150
NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766
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Tbc1d23
TBC1 domain family, member 23
increases expression
ISO
Hypochlorous Acid results in increased expression of TBC1D23 mRNA
CTD
PMID:19376150
NCBI chr11:43,303,355...43,361,507
Ensembl chr11:43,303,355...43,361,503
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Tbcd
tubulin folding cofactor D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBCD mRNA
CTD
PMID:19376150
NCBI chr10:106,717,340...106,874,126
Ensembl chr10:106,717,367...106,874,122
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Tbcel
tubulin folding cofactor E-like
increases expression
ISO
Hypochlorous Acid results in increased expression of TBCEL mRNA
CTD
PMID:19376150
NCBI chr 8:42,795,648...42,854,552
Ensembl chr 8:42,796,730...42,854,552
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Tbrg4
transforming growth factor beta regulator 4
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TBRG4 mRNA
CTD
PMID:19376150
NCBI chr14:81,481,977...81,490,781
Ensembl chr14:81,481,981...81,490,756
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Tfrc
transferrin receptor
increases expression
ISO
Hypochlorous Acid results in increased expression of TFRC mRNA
CTD
PMID:19376150
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Tifa
TRAF-interacting protein with forkhead-associated domain
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIFA mRNA
CTD
PMID:19376150
NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
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Timm44
translocase of inner mitochondrial membrane 44
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TIMM44 mRNA
CTD
PMID:19376150
NCBI chr12:2,612,581...2,629,374
Ensembl chr12:2,612,581...2,629,351
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Tjp3
tight junction protein 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TJP3 mRNA
CTD
PMID:19376150
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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Tmed2
transmembrane p24 trafficking protein 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TMED2 mRNA
CTD
PMID:19376150
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Tmem128
transmembrane protein 128
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM128 mRNA
CTD
PMID:19376150
NCBI chr14:72,539,530...72,548,623
Ensembl chr14:72,539,532...72,548,550
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Tmem33
transmembrane protein 33
increases expression
ISO
Hypochlorous Acid results in increased expression of TMEM33 mRNA
CTD
PMID:19376150
NCBI chr14:40,888,485...40,910,715
Ensembl chr14:40,885,712...40,910,715
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Tnrc6a
trinucleotide repeat containing adaptor 6A
increases expression
ISO
Hypochlorous Acid results in increased expression of TNRC6A mRNA
CTD
PMID:19376150
NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
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Topbp1
DNA topoisomerase II binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TOPBP1 mRNA
CTD
PMID:19376150
NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
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Tp53i11
tumor protein p53 inducible protein 11
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRP53I11 mRNA
CTD
PMID:19376150
NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
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Tpp2
tripeptidyl peptidase 2
increases expression
ISO
Hypochlorous Acid results in increased expression of TPP2 mRNA
CTD
PMID:19376150
NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157
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Trap1
TNF receptor-associated protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRAP1 mRNA
CTD
PMID:19376150
NCBI chr10:11,464,882...11,498,931
Ensembl chr10:11,464,821...11,498,981
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Treml4
triggering receptor expressed on myeloid cells-like 4
increases expression
ISO
Hypochlorous Acid results in increased expression of TREML4 mRNA
CTD
PMID:19376150
NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253
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Trim27
tripartite motif-containing 27
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRIM27 mRNA
CTD
PMID:19376150
NCBI chr17:43,538,282...43,550,633
Ensembl chr17:43,538,285...43,550,643
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Trpt1
tRNA phosphotransferase 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TRPT1 mRNA
CTD
PMID:19376150
NCBI chr 1:204,186,295...204,191,294
Ensembl chr 1:204,186,295...204,191,294
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Ttc1
tetratricopeptide repeat domain 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TTC1 mRNA
CTD
PMID:19376150
NCBI chr10:28,202,325...28,227,464
Ensembl chr10:28,202,325...28,227,472
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Ttll3
tubulin tyrosine ligase like 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of TTLL3 mRNA
CTD
PMID:19376150
NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
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Txndc9
thioredoxin domain containing 9
increases expression
ISO
Hypochlorous Acid results in increased expression of TXNDC9 mRNA
CTD
PMID:19376150
NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279 Ensembl chr 9:40,211,412...40,384,279
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
Hypochlorous Acid results in increased expression of TXNRD1 mRNA
CTD
PMID:18156441 PMID:19376150
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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Ube2d3
ubiquitin-conjugating enzyme E2D 3
increases expression
ISO
Hypochlorous Acid results in increased expression of UBE2D3 mRNA
CTD
PMID:19376150
NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
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Ugcg
UDP-glucose ceramide glucosyltransferase
increases expression
ISO
Hypochlorous Acid results in increased expression of UGCG mRNA
CTD
PMID:19376150
NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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Unc119
unc-119 lipid binding chaperone
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC119 mRNA
CTD
PMID:19376150
NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339
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Unc93b1
unc-93 homolog B1, TLR signaling regulator
decreases expression
ISO
Hypochlorous Acid results in decreased expression of UNC93B1 mRNA
CTD
PMID:19376150
NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338
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Uso1
USO1 vesicle transport factor
increases expression
ISO
Hypochlorous Acid results in increased expression of USO1 mRNA
CTD
PMID:19376150
NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171
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Usp12
ubiquitin specific peptidase 12
increases expression
ISO
Hypochlorous Acid results in increased expression of USP12 mRNA
CTD
PMID:19376150
NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656
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Usp15
ubiquitin specific peptidase 15
increases expression
ISO
Hypochlorous Acid results in increased expression of USP15 mRNA
CTD
PMID:19376150
NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
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Usp16
ubiquitin specific peptidase 16
increases expression
ISO
Hypochlorous Acid results in increased expression of USP16 mRNA
CTD
PMID:19376150
NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
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Usp2
ubiquitin specific peptidase 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of USP2 mRNA
CTD
PMID:19376150
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Vamp2
vesicle-associated membrane protein 2
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VAMP2 mRNA
CTD
PMID:19376150
NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
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Vars2
valyl-tRNA synthetase 2, mitochondrial
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VARS2 mRNA
CTD
PMID:19376150
NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994
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Vmp1
vacuole membrane protein 1
increases expression
ISO
Hypochlorous Acid results in increased expression of VMP1 mRNA
CTD
PMID:19376150
NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
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Vps13d
vacuolar protein sorting 13 homolog D
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS13D mRNA
CTD
PMID:19376150
NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891
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Vps16
VPS16 core subunit of CORVET and HOPS complexes
decreases expression
ISO
Hypochlorous Acid results in decreased expression of VPS16 mRNA
CTD
PMID:19376150
NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
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Vps35
VPS35 retromer complex component
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS35 mRNA
CTD
PMID:19376150
NCBI chr19:21,765,771...21,801,620
Ensembl chr19:21,765,749...21,801,618
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Vps54
VPS54 subunit of GARP complex
increases expression
ISO
Hypochlorous Acid results in increased expression of VPS54 mRNA
CTD
PMID:19376150
NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857
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Wbp1
WW domain binding protein 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WBP1 mRNA
CTD
PMID:19376150
NCBI chr 4:115,625,168...115,627,567
Ensembl chr 4:115,625,168...115,627,624
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Wdr62
WD repeat domain 62
decreases expression
ISO
Hypochlorous Acid results in decreased expression of WDR62 mRNA
CTD
PMID:19376150
NCBI chr 1:85,491,531...85,530,643
Ensembl chr 1:85,491,533...85,530,637
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
increases expression
ISO
Hypochlorous Acid results in increased expression of YWHAZ mRNA
CTD
PMID:19376150
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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Zbtb47
zinc finger and BTB domain containing 47
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZBTB47 mRNA
CTD
PMID:19376150
NCBI chr 8:121,420,758...121,434,365
Ensembl chr 8:121,423,696...121,433,225
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Zc3h15
zinc finger CCCH-type containing 15
increases expression
ISO
Hypochlorous Acid results in increased expression of ZC3H15 mRNA
CTD
PMID:19376150
NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333
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Zdhhc14
zinc finger DHHC-type palmitoyltransferase 14
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZDHHC14 mRNA
CTD
PMID:19376150
NCBI chr 1:46,069,127...46,340,806
Ensembl chr 1:46,069,127...46,330,488
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Zfp24
zinc finger protein 24
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP24 mRNA
CTD
PMID:19376150
NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799
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Zfp316
zinc finger protein 316
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP316 mRNA
CTD
PMID:19376150
NCBI chr12:11,294,445...11,313,841
Ensembl chr12:11,293,980...11,312,177
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Zfp414
zinc finger protein 414
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP414 mRNA
CTD
PMID:19376150
NCBI chr 7:14,420,232...14,422,939
Ensembl chr 7:14,420,165...14,438,166
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Zfp638
zinc finger protein 638
increases expression
ISO
Hypochlorous Acid results in increased expression of ZFP638 mRNA
CTD
PMID:19376150
NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845
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Zfp652
zinc finger protein 652
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFP652 mRNA
CTD
PMID:19376150
NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674
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Zfpm1
zinc finger protein, multitype 1
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZFPM1 mRNA
CTD
PMID:19376150
NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
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Zmym3
zinc finger MYM-type containing 3
decreases expression
ISO
Hypochlorous Acid results in decreased expression of ZMYM3 mRNA
CTD
PMID:19376150
NCBI chr X:66,528,585...66,544,234
Ensembl chr X:66,528,585...66,544,782
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Zwint
ZW10 interacting kinetochore protein
increases expression
ISO
Hypochlorous Acid results in increased expression of ZWINT mRNA
CTD
PMID:19376150
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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