CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: cerium
Accession: CHEBI:33369
browse the term
Definition: A lanthanoid atom that has formula Ce.
Synonyms: related_synonym: 58Ce; Ce; Cer; Zer; cerio
xref: CAS:7440-45-1; Gmelin:16275
xref_mesh: MESH:D002563
xref: WebElements:Ce
chemrof_formula: Ce
chemrof_inchikey: GWXLDORMOJMVQZ-UHFFFAOYSA-N
chemrof_inchi: InChI=1S/Ce
chemrof_smiles: [Ce]
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Ahr
aryl hydrocarbon receptor
affects expression
ISO
Cerium affects the expression of AHR mRNA
CTD
PMID:35641671
NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
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Atf4
activating transcription factor 4
affects expression
ISO
Cerium affects the expression of ATF4 mRNA
CTD
PMID:35641671
NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739
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Cacna1g
calcium voltage-gated channel subunit alpha1 G
multiple interactions
ISO
Cerium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD
PMID:12163980
NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,851,896...79,919,634
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Hif1a
hypoxia inducible factor 1 subunit alpha
decreases expression
ISO
Cerium results in decreased expression of HIF1A mRNA
CTD
PMID:35641671
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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Mtf1
metal-regulatory transcription factor 1
decreases expression
ISO
Cerium results in decreased expression of MTF1 mRNA
CTD
PMID:35641671
NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810
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Nfe2l2
NFE2 like bZIP transcription factor 2
decreases expression
ISO
Cerium results in decreased expression of NFE2L2 mRNA
CTD
PMID:35641671
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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Nfkb1
nuclear factor kappa B subunit 1
decreases expression
ISO
Cerium results in decreased expression of NFKB1 mRNA
CTD
PMID:35641671
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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Pparg
peroxisome proliferator-activated receptor gamma
decreases expression
ISO
Cerium results in decreased expression of PPARG mRNA
CTD
PMID:35641671
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
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Stat1
signal transducer and activator of transcription 1
affects expression
ISO
Cerium affects the expression of STAT1 mRNA
CTD
PMID:35641671
NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
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Stat2
signal transducer and activator of transcription 2
affects expression
ISO
Cerium affects the expression of STAT2 mRNA
CTD
PMID:35641671
NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459
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Tp53
tumor protein p53
decreases expression
ISO
Cerium results in decreased expression of TP53 mRNA
CTD
PMID:35641671
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Xbp1
X-box binding protein 1
decreases expression
ISO
Cerium results in decreased expression of XBP1 mRNA
CTD
PMID:35641671
NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706
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Akt1
AKT serine/threonine kinase 1
decreases expression
ISO
ceric oxide analog results in decreased expression of AKT1 mRNA
CTD
PMID:24821434
NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
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Alb
albumin
decreases expression increases secretion affects expression
EXP ISO
ceric oxide results in decreased expression of ALB protein ceric oxide results in increased secretion of ALB protein ceric oxide affects the expression of ALB mRNA
CTD
PMID:22072870 PMID:23726862 PMID:29463257
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Ap3d1
adaptor related protein complex 3 subunit delta 1
decreases expression
ISO
ceric oxide analog results in decreased expression of AP3D1 mRNA
CTD
PMID:24821434
NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:9,620,968...9,656,342
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Apaf1
apoptotic peptidase activating factor 1
increases expression
ISO
ceric oxide results in increased expression of APAF1 protein
CTD
PMID:24987704
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
ceric oxide results in increased expression of BAX protein
CTD
PMID:24987704
NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions
ISO
ceric oxide results in decreased expression of BCL2 protein [Air Pollutants results in increased abundance of ceric oxide] which results in decreased expression of BCL2 protein
CTD
PMID:24987704 PMID:36982514
NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
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Birc5
baculoviral IAP repeat-containing 5
increases expression
EXP
ceric oxide results in increased expression of BIRC5 mRNA
CTD
PMID:29463257
NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
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Brca1
BRCA1, DNA repair associated
decreases expression
EXP
ceric oxide results in decreased expression of BRCA1 mRNA
CTD
PMID:29463257
NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
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Ca9
carbonic anhydrase 9
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of CA9 protein; [Air Pollutants results in increased abundance of ceric oxide] which results in decreased expression of CA9 protein
CTD
PMID:36982514
NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626
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Casp3
caspase 3
increases cleavage increases expression
ISO
ceric oxide results in increased cleavage of CASP3 protein ceric oxide results in increased expression of CASP3 protein
CTD
PMID:24987704 PMID:26028148
NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
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Casp7
caspase 7
affects expression
ISO
ceric oxide analog affects the expression of CASP7 mRNA
CTD
PMID:22960666
NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
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Casp9
caspase 9
increases expression
ISO
ceric oxide results in increased expression of CASP9 protein
CTD
PMID:24987704
Ensembl chr 5:159,391,188...159,409,648
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Cat
catalase
decreases activity multiple interactions affects expression
ISO EXP
ceric oxide results in decreased activity of CAT protein Acetylcysteine inhibits the reaction [ceric oxide results in decreased activity of CAT protein] ceric oxide affects the expression of CAT protein
CTD
PMID:20457660 PMID:23416263
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Ccl11
C-C motif chemokine ligand 11
multiple interactions increases expression
ISO EXP
[Antigens, Dermatophagoides co-treated with ceric oxide] results in decreased expression of CCL11 mRNA; [Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CCL11 protein; ceric oxide promotes the reaction [Antigens, Dermatophagoides results in increased expression of CCL11 mRNA] ceric oxide results in increased expression of CCL11 mRNA
CTD
PMID:29463257 PMID:29792201
NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
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Ccl17
C-C motif chemokine ligand 17
multiple interactions increases expression
ISO EXP
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CCL17 mRNA ceric oxide results in increased expression of CCL17 mRNA
CTD
PMID:29463257 PMID:29792201
NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895
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Ccl2
C-C motif chemokine ligand 2
multiple interactions increases secretion increases expression
ISO EXP
[Antigens, Dermatophagoides co-treated with ceric oxide] results in decreased expression of CCL2 mRNA ceric oxide results in increased secretion of CCL2 protein ceric oxide results in increased expression of CCL2 mRNA
CTD
PMID:29463257 PMID:29792201
NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
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Ccl20
C-C motif chemokine ligand 20
multiple interactions affects expression
ISO EXP
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CCL20 mRNA ceric oxide affects the expression of CCL20 mRNA
CTD
PMID:29463257 PMID:29792201
NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
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Ccl22
C-C motif chemokine ligand 22
increases expression
EXP
ceric oxide results in increased expression of CCL22 mRNA
CTD
PMID:29463257
NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359
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Ccl24
C-C motif chemokine ligand 24
increases expression
EXP
ceric oxide results in increased expression of CCL24 mRNA
CTD
PMID:29463257
NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924
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Ccl26
C-C motif chemokine ligand 26
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CCL26 mRNA
CTD
PMID:29792201
NCBI chr12:26,745,972...26,750,924
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Ccl3
C-C motif chemokine ligand 3
increases expression
EXP
ceric oxide results in increased expression of CCL3 mRNA
CTD
PMID:29463257
NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
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Ccl4
C-C motif chemokine ligand 4
increases expression
EXP
ceric oxide results in increased expression of CCL4 mRNA
CTD
PMID:29463257
NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722
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Ccl7
C-C motif chemokine ligand 7
increases expression
EXP
ceric oxide results in increased expression of CCL7 mRNA
CTD
PMID:29463257
NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947
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Ccl9
C-C motif chemokine ligand 9
increases expression
EXP
ceric oxide results in increased expression of CCL9 mRNA
CTD
PMID:29463257
NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877
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Ccr2
C-C motif chemokine receptor 2
increases expression
EXP
ceric oxide results in increased expression of CCR2 mRNA
CTD
PMID:29463257
NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059
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Cd177
CD177 molecule
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CD177 mRNA
CTD
PMID:29792201
NCBI chr 1:89,467,926...89,488,490
Ensembl chr 1:89,467,926...89,488,443
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Cd40lg
CD40 ligand
decreases expression
EXP
ceric oxide results in decreased expression of CD40LG mRNA
CTD
PMID:29463257
NCBI chr X:140,164,341...140,176,057
Ensembl chr X:140,164,302...140,176,475
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Cd63
Cd63 molecule
increases expression
ISO
ceric oxide results in increased expression of CD63 protein
CTD
PMID:23726862
NCBI chr 7:1,909,538...1,924,937
Ensembl chr 7:1,922,169...1,924,938
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in increased expression of CDKN1A mRNA; [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in increased expression of CDKN1A protein; [Air Pollutants results in increased abundance of ceric oxide] which results in decreased expression of CDKN1A protein; [Air Pollutants results in increased abundance of ceric oxide] which results in increased expression of CDKN1A protein
CTD
PMID:36982514
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of CDKN1B protein
CTD
PMID:36982514
NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
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Clca1
chloride channel accessory 1
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CLCA1 mRNA [Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CLCA1 mRNA; ceric oxide promotes the reaction [Antigens, Dermatophagoides results in increased expression of CLCA1 protein]
CTD
PMID:29792201
NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714
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Clec10a
C-type lectin domain containing 10A
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CLEC10A mRNA
CTD
PMID:29792201
NCBI chr10:55,374,914...55,379,110
Ensembl chr10:55,374,887...55,379,108
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Cx3cl1
C-X3-C motif chemokine ligand 1
increases expression
EXP
ceric oxide results in increased expression of CX3CL1 mRNA
CTD
PMID:29463257
NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999
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Cx3cr1
C-X3-C motif chemokine receptor 1
affects expression
EXP
ceric oxide affects the expression of CX3CR1 mRNA
CTD
PMID:29463257
NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
ceric oxide inhibits the reaction [Antigens, Dermatophagoides results in increased expression of CXCL10 mRNA]
CTD
PMID:29792201
NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261
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Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
EXP
ceric oxide results in decreased expression of CXCL12 mRNA
CTD
PMID:29463257
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
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Cxcl9
C-X-C motif chemokine ligand 9
affects expression
EXP
ceric oxide affects the expression of CXCL9 mRNA
CTD
PMID:29463257
NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299
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Cxcr2
C-X-C motif chemokine receptor 2
increases expression
EXP
ceric oxide results in increased expression of CXCR2 mRNA
CTD
PMID:29463257
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:83,183,808...83,188,602
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Cxcr3
C-X-C motif chemokine receptor 3
increases expression
EXP
ceric oxide results in increased expression of CXCR3 mRNA
CTD
PMID:29463257
NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871
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Cxcr5
C-X-C motif chemokine receptor 5
decreases expression
EXP
ceric oxide results in decreased expression of CXCR5 mRNA
CTD
PMID:29463257
NCBI chr 8:53,738,878...53,756,813
Ensembl chr 8:53,740,197...53,754,816
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in increased expression of CYP1A1 mRNA; [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in increased expression of CYP1A1 protein; [Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of CYP1A1 mRNA
CTD
PMID:29792201 PMID:36982514
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
affects expression
EXP
ceric oxide affects the expression of CYP1B1 mRNA
CTD
PMID:29463257
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
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Dbnl
drebrin-like
decreases expression
ISO
ceric oxide analog results in decreased expression of DBNL mRNA
CTD
PMID:24821434
NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133
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Dkk4
dickkopf WNT signaling pathway inhibitor 4
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of DKK4 protein
CTD
PMID:36982514
NCBI chr16:76,105,679...76,109,044
Ensembl chr16:76,105,679...76,109,044
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Epas1
endothelial PAS domain protein 1
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of EPAS1 protein; [Air Pollutants results in increased abundance of ceric oxide] which results in decreased expression of EPAS1 protein
CTD
PMID:36982514
NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729
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Epx
eosinophil peroxidase
decreases expression
EXP
ceric oxide results in decreased expression of EPX mRNA
CTD
PMID:29463257
NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180
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Exo1
exonuclease 1
affects expression
EXP
ceric oxide affects the expression of EXO1 mRNA
CTD
PMID:29463257
NCBI chr13:90,341,947...90,366,861
Ensembl chr13:90,342,018...90,366,861
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Fabp4
fatty acid binding protein 4
increases expression
EXP
ceric oxide results in increased expression of FABP4 mRNA
CTD
PMID:29463257
NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
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Gclc
glutamate-cysteine ligase, catalytic subunit
decreases expression
EXP
ceric oxide results in decreased expression of GCLC mRNA
CTD
PMID:29463257
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
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Gclm
glutamate cysteine ligase, modifier subunit
decreases expression
EXP
ceric oxide results in decreased expression of GCLM mRNA
CTD
PMID:29463257
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
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Gpx2
glutathione peroxidase 2
decreases expression
EXP
ceric oxide results in decreased expression of GPX2 mRNA
CTD
PMID:29463257
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
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Hba-a2
hemoglobin alpha, adult chain 2
decreases expression
EXP
ceric oxide results in decreased expression of HBA1 mRNA
CTD
PMID:29463257
NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141
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Hfe
homeostatic iron regulator
decreases expression
ISO
ceric oxide analog results in decreased expression of HFE mRNA
CTD
PMID:24821434
NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of HIF1A protein; [Air Pollutants results in increased abundance of ceric oxide] which results in decreased expression of HIF1A protein
CTD
PMID:36982514
NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
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Hmox1
heme oxygenase 1
affects expression increases expression decreases expression multiple interactions
ISO
ceric oxide analog affects the expression of HMOX1 mRNA ceric oxide results in increased expression of HMOX1 protein ceric oxide results in decreased expression of HMOX1 mRNA ceric oxide inhibits the reaction [potassium bromate results in increased expression of HMOX1 mRNA]
CTD
PMID:19429248 PMID:22960666 PMID:25618551
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
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Id2
inhibitor of DNA binding 2
decreases expression
ISO
ceric oxide analog results in decreased expression of ID2 mRNA
CTD
PMID:24821434
NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961
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Ifit1
interferon-induced protein with tetratricopeptide repeats 1
multiple interactions
ISO
ceric oxide inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IFIT1 mRNA]
CTD
PMID:29792201
NCBI chr 1:241,565,197...241,567,262
Ensembl chr 1:241,543,184...241,568,148
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Il13
interleukin 13
multiple interactions
ISO
ceric oxide inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL13 mRNA]
CTD
PMID:29792201
NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
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Il1a
interleukin 1 alpha
increases expression
EXP
ceric oxide results in increased expression of IL1A mRNA
CTD
PMID:29463257
NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
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Il1b
interleukin 1 beta
increases expression
EXP
ceric oxide results in increased expression of IL1B mRNA; ceric oxide results in increased expression of IL1B protein
CTD
PMID:21624445 PMID:29463257
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il1rn
interleukin 1 receptor antagonist
increases expression
EXP
ceric oxide results in increased expression of IL1RN mRNA
CTD
PMID:29463257
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
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Il2rb
interleukin 2 receptor subunit beta
decreases expression
EXP
ceric oxide results in decreased expression of IL2RB mRNA
CTD
PMID:29463257
NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:111,913,828...111,928,537
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Il2rg
interleukin 2 receptor subunit gamma
increases expression
EXP
ceric oxide results in increased expression of IL2RG mRNA
CTD
PMID:29463257
NCBI chr X:70,435,340...70,439,052
Ensembl chr X:70,435,343...70,439,161
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Il4
interleukin 4
multiple interactions
ISO
ceric oxide promotes the reaction [Antigens, Dermatophagoides results in increased expression of IL4 mRNA]
CTD
PMID:29792201
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il6
interleukin 6
increases expression multiple interactions
EXP ISO
ceric oxide results in increased expression of IL6 protein [Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of IL6 mRNA
CTD
PMID:21624445 PMID:29792201
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Irf7
interferon regulatory factor 7
multiple interactions
ISO
ceric oxide inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IRF7 mRNA]
CTD
PMID:29792201
NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
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Kif13b
kinesin family member 13B
increases expression
ISO
ceric oxide analog results in increased expression of KIF13B mRNA
CTD
PMID:24821434
NCBI chr15:43,084,059...43,241,719
Ensembl chr15:43,080,910...43,241,719
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Kitlg
KIT ligand
increases expression
ISO
ceric oxide analog results in increased expression of KITLG mRNA
CTD
PMID:24821434
NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
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Lig4
DNA ligase 4
affects expression
EXP
ceric oxide affects the expression of LIG4 mRNA
CTD
PMID:29463257
NCBI chr16:86,220,345...86,228,930
Ensembl chr16:86,220,279...86,229,926
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Lpo
lactoperoxidase
increases expression
EXP
ceric oxide results in increased expression of LPO mRNA; ceric oxide results in increased expression of LPO protein
CTD
PMID:29463257
NCBI chr10:73,104,170...73,124,683
Ensembl chr10:73,104,188...73,123,456
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Mapk1
mitogen activated protein kinase 1
increases phosphorylation multiple interactions
ISO
ceric oxide results in increased phosphorylation of MAPK1 protein Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK1 protein]
CTD
PMID:23416263
NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
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Mapk3
mitogen activated protein kinase 3
multiple interactions increases phosphorylation
ISO
Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK3 protein]
CTD
PMID:23416263
NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
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Mmp12
matrix metallopeptidase 12
multiple interactions increases expression
ISO EXP
ceric oxide promotes the reaction [Antigens, Dermatophagoides results in increased expression of MMP12 mRNA] ceric oxide results in increased expression of MMP12 mRNA; ceric oxide results in increased expression of MMP12 protein
CTD
PMID:29463257 PMID:29792201
NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478
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Mmp9
matrix metallopeptidase 9
increases activity increases secretion
ISO
ceric oxide results in increased activity of MMP9 protein ceric oxide results in increased secretion of MMP9 protein
CTD
PMID:23726862
NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
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Mpo
myeloperoxidase
increases secretion increases expression
ISO EXP
ceric oxide results in increased secretion of MPO protein ceric oxide results in increased expression of MPO mRNA
CTD
PMID:23726862 PMID:29463257
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Msh5
mutS homolog 5
increases expression
EXP
ceric oxide results in increased expression of MSH5 mRNA
CTD
PMID:29463257
NCBI chr20:3,779,180...3,797,996
Ensembl chr20:3,781,578...3,797,994
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Muc1
mucin 1, cell surface associated
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of MUC1 mRNA
CTD
PMID:29792201
NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491
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Muc5ac
mucin 5AC, oligomeric mucus/gel-forming
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of MUC5AC mRNA
CTD
PMID:29792201
NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:206,293,869...206,326,006
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Mutyh
mutY DNA glycosylase
decreases expression
EXP
ceric oxide results in decreased expression of MUTYH mRNA
CTD
PMID:29463257
NCBI chr 5:135,510,666...135,522,777
Ensembl chr 5:135,517,695...135,522,776
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Ncf2
neutrophil cytosolic factor 2
increases expression decreases expression
EXP
ceric oxide results in increased expression of NCF2 mRNA ceric oxide results in decreased expression of NCF2 mRNA
CTD
PMID:29463257
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
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Nfe2l2
NFE2 like bZIP transcription factor 2
affects localization
ISO
ceric oxide affects the localization of NFE2L2 protein
CTD
PMID:19429248
NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of NFKB1 protein
CTD
PMID:36982514
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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Ngb
neuroglobin
decreases expression
EXP
ceric oxide results in decreased expression of NGB mRNA
CTD
PMID:29463257
NCBI chr 6:112,475,332...112,480,786
Ensembl chr 6:112,475,332...112,480,786
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Noxo1
NADPH oxidase organizer 1
increases expression
EXP
ceric oxide results in increased expression of NOXO1 mRNA
CTD
PMID:29463257
NCBI chr10:14,226,473...14,230,541
Ensembl chr10:14,228,205...14,230,541
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of NQO1 mRNA
CTD
PMID:29792201
NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
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Opcml
opioid binding protein/cell adhesion molecule-like
increases expression
EXP
ceric oxide results in increased expression of OPCML mRNA
CTD
PMID:29463257
NCBI chr 8:34,451,629...35,562,897
Ensembl chr 8:34,451,500...35,558,966
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Osm
oncostatin M
affects expression
EXP
ceric oxide affects the expression of OSM mRNA
CTD
PMID:29463257
NCBI chr14:83,327,202...83,332,073
Ensembl chr14:83,327,554...83,331,827
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Pf4
platelet factor 4
increases expression
EXP
ceric oxide results in increased expression of PF4 mRNA
CTD
PMID:29463257
NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,582,477...17,583,392
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Pon3
paraoxonase 3
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of PON3 protein
CTD
PMID:36982514
NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244
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Prdx1
peroxiredoxin 1
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased oxidation of PRDX1 protein modified form; [Air Pollutants results in increased abundance of ceric oxide] which results in decreased oxidation of PRDX1 protein modified form
CTD
PMID:36982514
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
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RT1-CE16
RT1 class I, locus CE16
decreases expression
ISO
ceric oxide analog results in decreased expression of HLA-A mRNA
CTD
PMID:24821434
NCBI chr20:3,261,656...3,265,548
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Scd
stearoyl-CoA desaturase
affects expression
EXP
ceric oxide affects the expression of SCD1 mRNA
CTD
PMID:29463257
NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
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Sectm1b
secreted and transmembrane 1B
decreases expression
ISO
ceric oxide analog results in decreased expression of SECTM1 mRNA
CTD
PMID:24821434
NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104
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Sirt2
sirtuin 2
multiple interactions
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of SIRT2 protein
CTD
PMID:36982514
NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
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Slc26a4
solute carrier family 26 member 4
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of SLC26A4 mRNA [Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of SLC26A4 mRNA; ceric oxide promotes the reaction [Antigens, Dermatophagoides results in increased expression of SLC26A4 mRNA]
CTD
PMID:29792201
NCBI chr 6:53,835,102...53,873,968
Ensembl chr 6:53,835,110...53,873,216
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Smug1
single-strand-selective monofunctional uracil-DNA glycosylase 1
increases expression
EXP
ceric oxide results in increased expression of SMUG1 mRNA
CTD
PMID:29463257
NCBI chr 7:136,166,157...136,177,673
Ensembl chr 7:136,167,532...136,170,658
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Sod2
superoxide dismutase 2
multiple interactions increases expression
ISO
[Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in decreased expression of SOD2 protein; ceric oxide inhibits the reaction [potassium bromate results in increased expression of SOD2 mRNA] ceric oxide results in increased expression of SOD2 mRNA
CTD
PMID:25618551 PMID:36982514
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
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Spp1
secreted phosphoprotein 1
decreases expression
EXP
ceric oxide results in decreased expression of SPP1 mRNA
CTD
PMID:29463257
NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
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Tafazzin
tafazzin, phospholipid-lysophospholipid transacylase
decreases expression
ISO
ceric oxide analog results in decreased expression of TAFAZZIN mRNA
CTD
PMID:24821434
NCBI chr X:157,216,826...157,230,524
Ensembl chr X:157,216,554...157,225,287
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Tirap
TIR domain containing adaptor protein
decreases expression
ISO
ceric oxide analog results in decreased expression of TIRAP mRNA
CTD
PMID:24821434
NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:41,791,878...41,796,312
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Tlr6
toll-like receptor 6
decreases expression
ISO
ceric oxide analog results in decreased expression of TLR6 mRNA
CTD
PMID:24821434
NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,698,751...43,740,462
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Tnf
tumor necrosis factor
increases expression
EXP ISO
ceric oxide results in increased expression of TNF protein
CTD
PMID:21624445 PMID:27693598
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Tnfsf4
TNF superfamily member 4
affects expression
EXP
ceric oxide affects the expression of TNFSF4 mRNA
CTD
PMID:29463257
NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133
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Tollip
toll interacting protein
decreases expression
ISO
ceric oxide analog results in decreased expression of TOLLIP mRNA
CTD
PMID:24821434
NCBI chr 1:206,391,120...206,413,809
Ensembl chr 1:206,380,308...206,411,988
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Tp53
tumor protein p53
increases phosphorylation multiple interactions
ISO
ceric oxide results in increased phosphorylation of TP53 protein [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in increased expression of TP53 protein; [Air Pollutants results in increased abundance of ceric oxide] which results in increased expression of TP53 protein
CTD
PMID:24987704 PMID:36982514
NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
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Tslp
thymic stromal lymphopoietin
multiple interactions
ISO
[Antigens, Dermatophagoides co-treated with ceric oxide] results in increased expression of TSLP mRNA
CTD
PMID:29792201
NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420
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Txnip
thioredoxin interacting protein
decreases expression
EXP
ceric oxide results in decreased expression of TXNIP mRNA
CTD
PMID:29463257
NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
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Alb
albumin
affects expression
ISO
cerous chloride affects the expression of ALB mRNA
CTD
PMID:23139204
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
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Alox12
arachidonate 12-lipoxygenase, 12S type
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of ALOX12 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA
CTD
PMID:28954213
NCBI chr10:55,456,923...55,469,239
Ensembl chr10:55,456,928...55,469,199
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Aox1
aldehyde oxidase 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of AOX1 mRNA
CTD
PMID:28954213
NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
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Apoa4
apolipoprotein A4
affects expression
ISO
cerous chloride affects the expression of APOA4 mRNA
CTD
PMID:23139204
NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164
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Apoe
apolipoprotein E
affects expression multiple interactions
ISO
cerous chloride affects the expression of APOE mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of APOE mRNA
CTD
PMID:28954213
NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
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B2m
beta-2 microglobulin
increases expression
ISO
cerous chloride results in increased expression of B2M mRNA
CTD
PMID:28954213
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
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Cat
catalase
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of CAT mRNA cerous chloride results in decreased expression of CAT mRNA
CTD
PMID:28954213
NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
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Ccl5
C-C motif chemokine ligand 5
increases expression multiple interactions
ISO
cerous chloride results in increased expression of CCL5 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of CCL5 mRNA
CTD
PMID:28954213
NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884
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Ccs
copper chaperone for superoxide dismutase
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] affects the expression of CCS mRNA cerous chloride results in decreased expression of CCS mRNA
CTD
PMID:28954213
NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
decreases expression
ISO
cerous chloride results in decreased expression of CDKN1A mRNA
CTD
PMID:23139204
NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
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Cel
carboxyl ester lipase
increases expression
ISO
cerous chloride results in increased expression of CEL mRNA
CTD
PMID:23139204
NCBI chr 3:32,281,518...32,289,019
Ensembl chr 3:32,281,518...32,289,019
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Cfd
complement factor D
affects expression
ISO
cerous chloride affects the expression of CFD mRNA
CTD
PMID:23139204
NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
increases expression
ISO
cerous chloride results in increased expression of CHUK mRNA; cerous chloride results in increased expression of CHUK protein
CTD
PMID:21656643
NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
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Cygb
cytoglobin
affects expression multiple interactions
ISO
cerous chloride affects the expression of CYGB mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of CYGB mRNA
CTD
PMID:28954213
NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
ISO
cerous chloride results in increased expression of CYP1A1
CTD
PMID:23712967
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
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Cyp51
cytochrome P450, family 51
affects expression
ISO
cerous chloride affects the expression of CYP51 mRNA
CTD
PMID:23139204
NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450
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Cyp7b1
cytochrome P450 family 7 subfamily B member 1
increases expression
ISO
cerous chloride results in increased expression of CYP7B1 mRNA
CTD
PMID:23139204
NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804
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Cyp8b1
cytochrome P450 family 8 subfamily B member 1
affects expression
ISO
cerous chloride affects the expression of CYP8B1 mRNA
CTD
PMID:23139204
NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689
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Dhcr24
24-dehydrocholesterol reductase
decreases expression
ISO
cerous chloride results in decreased expression of DHCR24 mRNA
CTD
PMID:28954213
NCBI chr 5:126,573,366...126,599,940
Ensembl chr 5:126,573,338...126,599,936
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Dhcr7
7-dehydrocholesterol reductase
affects expression
ISO
cerous chloride affects the expression of DHCR7 mRNA
CTD
PMID:23139204
NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382
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Duox1
dual oxidase 1
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of DUOX1 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX1 mRNA
CTD
PMID:28954213
NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187
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Duox2
dual oxidase 2
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX2 mRNA
CTD
PMID:28954213
NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203
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Dusp1
dual specificity phosphatase 1
multiple interactions affects expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUSP1 mRNA cerous chloride affects the expression of DUSP1 mRNA
CTD
PMID:28954213
NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
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Ebp
EBP, cholestenol delta-isomerase
affects expression
ISO
cerous chloride affects the expression of EBP mRNA
CTD
PMID:23139204
NCBI chr X:16,971,372...16,977,782
Ensembl chr X:16,971,405...16,977,781
G
Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression
ISO
cerous chloride affects the expression of EHHADH mRNA
CTD
PMID:23139204
NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662
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Ephx2
epoxide hydrolase 2
affects expression multiple interactions
ISO
cerous chloride affects the expression of EPHX2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of EPHX2 mRNA
CTD
PMID:28954213
NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160
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Epx
eosinophil peroxidase
decreases expression
ISO
cerous chloride results in decreased expression of EPX mRNA
CTD
PMID:28954213
NCBI chr10:73,164,096...73,175,180
Ensembl chr10:73,164,096...73,175,180
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Foxm1
forkhead box M1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of FOXM1 mRNA cerous chloride results in decreased expression of FOXM1 mRNA
CTD
PMID:28954213
NCBI chr 4:163,325,628...163,338,100
Ensembl chr 4:163,325,614...163,337,172
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Fth1
ferritin heavy chain 1
increases expression
ISO
cerous chloride results in increased expression of FTH1 mRNA
CTD
PMID:28954213
NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of GAPDH mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA
CTD
PMID:28954213
NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377
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Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression multiple interactions
ISO
cerous chloride results in increased expression of GCLC mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of GCLC mRNA
CTD
PMID:28954213
NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
G
Gclm
glutamate cysteine ligase, modifier subunit
decreases expression
ISO
cerous chloride results in decreased expression of GCLM mRNA
CTD
PMID:28954213
NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
G
Gpd2
glycerol-3-phosphate dehydrogenase 2
affects expression
ISO
cerous chloride affects the expression of GPD2 mRNA
CTD
PMID:23139204
NCBI chr 3:62,209,432...62,346,590
Ensembl chr 3:62,210,814...62,346,593
G
Gpx2
glutathione peroxidase 2
decreases expression
ISO
cerous chloride results in decreased expression of GPX2 mRNA
CTD
PMID:28954213
NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862
G
Gpx3
glutathione peroxidase 3
multiple interactions affects expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GPX3 mRNA cerous chloride affects the expression of GPX3 mRNA
CTD
PMID:28954213
NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405
G
Gpx4
glutathione peroxidase 4
affects expression
ISO
cerous chloride affects the expression of GPX4 mRNA
CTD
PMID:28954213
NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
G
Gpx7
glutathione peroxidase 7
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of GPX7 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of GPX7 mRNA
CTD
PMID:28954213
NCBI chr 5:128,373,881...128,381,866
Ensembl chr 5:128,372,875...128,381,725
G
Grb2
growth factor receptor bound protein 2
affects expression
ISO
cerous chloride affects the expression of GRB2 mRNA
CTD
PMID:23139204
NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138
G
Gstp1
glutathione S-transferase pi 1
decreases expression
ISO
cerous chloride results in decreased expression of GSTP1 mRNA
CTD
PMID:28954213
NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
G
Gstz1
glutathione S-transferase zeta 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GSTZ1 mRNA
CTD
PMID:28954213
NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233
G
Gtf2i
general transcription factor II I
decreases expression
ISO
cerous chloride results in decreased expression of GTF2I mRNA
CTD
PMID:28954213
NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677
G
Hmox1
heme oxygenase 1
multiple interactions affects expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of HMOX1 mRNA cerous chloride affects the expression of HMOX1 mRNA
CTD
PMID:28954213
NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
G
Hspa1a
heat shock protein family A (Hsp70) member 1A
decreases expression
ISO
cerous chloride results in decreased expression of HSPA1A mRNA
CTD
PMID:28954213
NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979
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Ifng
interferon gamma
increases expression
ISO
cerous chloride results in increased expression of IFNG
CTD
PMID:23712967
NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
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Ikbkb
inhibitor of nuclear factor kappa B kinase subunit beta
increases expression
ISO
cerous chloride results in increased expression of IKBKB mRNA; cerous chloride results in increased expression of IKBKB protein
CTD
PMID:21656643
NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
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Il10
interleukin 10
increases expression
ISO
cerous chloride results in increased expression of IL10
CTD
PMID:23712967
NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
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Il18
interleukin 18
increases expression
ISO
cerous chloride results in increased expression of IL18
CTD
PMID:23712967
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
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Il1b
interleukin 1 beta
increases expression
ISO
cerous chloride results in increased expression of IL1B
CTD
PMID:23712967
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
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Il2
interleukin 2
decreases expression increases expression
ISO
cerous chloride results in decreased expression of IL2 mRNA; cerous chloride results in decreased expression of IL2 protein cerous chloride results in increased expression of IL2
CTD
PMID:21656643 PMID:23712967
NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
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Il4
interleukin 4
increases expression
ISO
cerous chloride results in increased expression of IL4
CTD
PMID:23712967
NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
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Il6
interleukin 6
multiple interactions increases expression
ISO
IL6 mutant form inhibits the reaction [cerous chloride results in increased expression of SAA protein] cerous chloride results in increased expression of IL6; cerous chloride results in increased expression of IL6 protein
CTD
PMID:16204935 PMID:23712967
NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
affects expression
ISO
cerous chloride affects the expression of JUN mRNA
CTD
PMID:23139204
NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
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Lpo
lactoperoxidase
multiple interactions increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of LPO mRNA cerous chloride results in increased expression of LPO mRNA
CTD
PMID:28954213
NCBI chr10:73,104,170...73,124,683
Ensembl chr10:73,104,188...73,123,456
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
cerous chloride results in increased expression of MAP1LC3B protein
CTD
PMID:38253231
NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358 Ensembl chr16:66,574,407...66,584,358
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Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
increases expression
ISO
cerous chloride results in increased expression of MAP4K4 mRNA; cerous chloride results in increased expression of MAP4K4 protein
CTD
PMID:21656643
NCBI chr 9:49,696,573...49,822,353
Ensembl chr 9:49,696,700...49,822,353
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Mb
myoglobin
increases expression multiple interactions
ISO
cerous chloride results in increased expression of MB mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of MB mRNA
CTD
PMID:28954213
NCBI chr 7:110,640,511...110,647,742
Ensembl chr 7:110,640,512...110,647,958
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Mbl2
mannose binding lectin 2
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of MBL2 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of MBL2 mRNA
CTD
PMID:28954213
NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546
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Mif
macrophage migration inhibitory factor
increases expression
ISO
cerous chloride results in increased expression of MIF
CTD
PMID:23712967
NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121 Ensembl chr20:134,041,774...134,042,121
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Mpo
myeloperoxidase
affects expression
ISO
cerous chloride affects the expression of MPO mRNA
CTD
PMID:28954213
NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
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Mpv17
mitochondrial inner membrane protein MPV17
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MPV17 mRNA cerous chloride results in decreased expression of MPV17 mRNA
CTD
PMID:28954213
NCBI chr 6:30,941,693...30,956,389
Ensembl chr 6:30,943,356...30,956,386
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Msra
methionine sulfoxide reductase A
decreases expression
ISO
cerous chloride results in decreased expression of MSRA mRNA
CTD
PMID:28954213
NCBI chr15:42,514,818...42,853,278
Ensembl chr15:42,527,045...42,853,279
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Mt1a
metallothionein 1A
increases expression multiple interactions
ISO
cerous chloride results in increased expression of MT1 protein cerous chloride promotes the reaction [Zinc binds to MT1 protein]
CTD
PMID:15964310 PMID:16204935
NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200 Ensembl chr X:79,695,809...79,696,200 Ensembl chr19:79,695,809...79,696,200
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Mt2
metallothionein 2
multiple interactions increases expression
ISO
cerous chloride promotes the reaction [Zinc binds to MT2 protein] cerous chloride results in increased expression of MT2 protein
CTD
PMID:15964310 PMID:16204935
NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
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Ncf1
neutrophil cytosolic factor 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF1 mRNA
CTD
PMID:28954213
NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
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Ncf2
neutrophil cytosolic factor 2
affects expression multiple interactions
ISO
cerous chloride affects the expression of NCF2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF2 mRNA
CTD
PMID:28954213
NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
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Nfkb1
nuclear factor kappa B subunit 1
increases expression
ISO
cerous chloride results in increased expression of NFKB1 mRNA; cerous chloride results in increased expression of NFKB1 protein
CTD
PMID:21656643
NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
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Nfkb2
nuclear factor kappa B subunit 2
increases expression
ISO
cerous chloride results in increased expression of NFKB2 mRNA; cerous chloride results in increased expression of NFKB2 protein
CTD
PMID:21656643
NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
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Nfkbib
NFKB inhibitor beta
decreases expression
ISO
cerous chloride results in decreased expression of NFKBIB mRNA; cerous chloride results in decreased expression of NFKBIB protein
CTD
PMID:21656643
NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366
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Nnmt
nicotinamide N-methyltransferase
affects expression
ISO
cerous chloride affects the expression of NNMT mRNA
CTD
PMID:23139204
NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174
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Nos2
nitric oxide synthase 2
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of NOS2 mRNA [cerous chloride co-treated with lanthanum chloride] results in increased expression of NOS2 mRNA
CTD
PMID:28954213
NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
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Npm1
nucleophosmin 1
multiple interactions
ISO
cerous chloride results in decreased expression of and affects the localization of NPM1 protein
CTD
PMID:38253231
NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024 Ensembl chr X:18,245,740...18,256,024
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Nt5e
5' nucleotidase, ecto
decreases expression
ISO
cerous chloride results in decreased expression of NT5E mRNA
CTD
PMID:23139204
NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645
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Nudt1
nudix hydrolase 1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of NUDT1 mRNA cerous chloride results in decreased expression of NUDT1 mRNA
CTD
PMID:28954213
NCBI chr12:19,416,411...19,423,448
Ensembl chr12:19,416,411...19,424,158
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Pcna
proliferating cell nuclear antigen
affects expression multiple interactions
ISO
cerous chloride affects the expression of PCNA protein [cerous chloride co-treated with lanthanum chloride] affects the expression of PCNA protein
CTD
PMID:28954213
NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
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Pnkp
polynucleotide kinase 3'-phosphatase
decreases expression
ISO
cerous chloride results in decreased expression of PNKP mRNA
CTD
PMID:28954213
NCBI chr 1:104,476,801...104,483,409
Ensembl chr 1:104,478,088...104,483,408
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Prdx1
peroxiredoxin 1
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PRDX1 mRNA cerous chloride results in decreased expression of PRDX1 mRNA
CTD
PMID:28954213
NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
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Prdx2
peroxiredoxin 2
decreases expression
ISO
cerous chloride results in decreased expression of PRDX2 mRNA
CTD
PMID:28954213
NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
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Prdx5
peroxiredoxin 5
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of PRDX5 mRNA
CTD
PMID:28954213
NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020
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Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PREX1 mRNA
CTD
PMID:28954213
NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:175,726,012...175,875,764
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Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
cerous chloride results in decreased expression of PTGS2 mRNA
CTD
PMID:28954213
NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
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Pxdn
peroxidasin
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PXDN mRNA cerous chloride results in decreased expression of PXDN mRNA
CTD
PMID:28954213
NCBI chr 6:52,308,347...52,385,943
Ensembl chr 6:52,308,364...52,385,942
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Rad51
RAD51 recombinase
multiple interactions
ISO
[cerous chloride co-treated with Cisplatin] results in increased expression of RAD51 protein
CTD
PMID:38253231
NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469
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Rela
RELA proto-oncogene, NF-kB subunit
increases expression
ISO
cerous chloride results in increased expression of RELA mRNA; cerous chloride results in increased expression of RELA protein
CTD
PMID:21656643
NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
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Scara3
scavenger receptor class A, member 3
decreases expression
ISO
cerous chloride results in decreased expression of SCARA3 mRNA
CTD
PMID:28954213
NCBI chr15:44,315,422...44,348,416
Ensembl chr15:44,315,422...44,348,551
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Selenop
selenoprotein P
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SELENOP mRNA
CTD
PMID:28954213
NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019
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Sirt2
sirtuin 2
multiple interactions decreases expression increases expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SIRT2 mRNA cerous chloride results in decreased expression of SIRT2 mRNA cerous chloride results in increased expression of SIRT2 mRNA
CTD
PMID:28954213
NCBI chr 1:93,181,472...93,204,499
Ensembl chr 1:93,181,224...93,204,499
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Sod1
superoxide dismutase 1
decreases activity
ISO
cerous chloride results in decreased activity of SOD1 protein
CTD
PMID:15964310
NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
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Sod2
superoxide dismutase 2
decreases activity multiple interactions
ISO
cerous chloride results in decreased activity of SOD2 protein [cerous chloride co-treated with lanthanum chloride] results in increased expression of SOD2 mRNA
CTD
PMID:15964310 PMID:28954213
NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
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Sqstm1
sequestosome 1
multiple interactions affects expression
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA cerous chloride affects the expression of SQSTM1 mRNA
CTD
PMID:28954213
NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
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Srxn1
sulfiredoxin 1
multiple interactions
ISO
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SRXN1 mRNA
CTD
PMID:28954213
NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
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Stk25
serine/threonine kinase 25
decreases expression multiple interactions
ISO
cerous chloride results in decreased expression of STK25 mRNA [cerous chloride co-treated with lanthanum chloride] results in decreased expression of STK25 mRNA
CTD
PMID:28954213
NCBI chr 9:101,609,218...101,621,458
Ensembl chr 9:101,609,221...101,621,359
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Tgfb1
transforming growth factor, beta 1
increases expression
ISO
cerous chloride results in increased expression of TGFB1
CTD
PMID:23712967
NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
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Tlr2
toll-like receptor 2
increases expression
ISO
cerous chloride results in increased expression of TLR2 mRNA; cerous chloride results in increased expression of TLR2 protein
CTD
PMID:21656643
NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
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Tlr4
toll-like receptor 4
increases expression
ISO
cerous chloride results in increased expression of TLR4 mRNA; cerous chloride results in increased expression of TLR4 protein
CTD
PMID:21656643
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
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Tnf
tumor necrosis factor
increases expression
ISO
cerous chloride results in increased expression of TNF; cerous chloride results in increased expression of TNF mRNA; cerous chloride results in increased expression of TNF protein
CTD
PMID:21656643 PMID:23712967
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
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Txn1
thioredoxin 1
increases expression
ISO
cerous chloride results in increased expression of TXN mRNA
CTD
PMID:28954213
NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
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Txnrd1
thioredoxin reductase 1
increases expression
ISO
cerous chloride results in increased expression of TXNRD1 mRNA
CTD
PMID:28954213
NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
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Txnrd2
thioredoxin reductase 2
decreases expression
ISO
cerous chloride results in decreased expression of TXNRD2 mRNA
CTD
PMID:28954213
NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475
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Ucp2
uncoupling protein 2
multiple interactions decreases expression
ISO
[cerous chloride co-treated with lanthanum chloride] affects the expression of UCP2 mRNA cerous chloride results in decreased expression of UCP2 mRNA
CTD
PMID:28954213
NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
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Zap70
zeta chain of T cell receptor associated protein kinase 70
affects expression
ISO
cerous chloride affects the expression of ZAP70 mRNA
CTD
PMID:23139204
NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:46,485,598...46,509,062
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